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Potency: Group: Biochemicals. Alternative Names: Vitamin D3. Grades: Highly Purified. CAS No. 67-97-0. Pack Sizes: 500g, 1kg, 2kg, 5kg, 10kg. US Biological Life Sciences.
Worldwide
CHOLECALCIFEROL-CHOLESTEROL
CHOLECALCIFEROL-CHOLESTEROL. Product ID: ACMA00005139. Alfa Chemistry - ISO 9001:32057 Certified.
Cholecalciferol-[d6]
Cholecalciferol-[d6] is the labelled analogue of Cholecalciferol (Vitamin D3), which is the vitamin that mediates intestinal calcium absorption, bone calcium metabolism and probably, muscle activity. Synonyms: Cholecalciferol D6; VD3-D6; Vitamin D3 (26,26,26,27,27,27-d6); Vitamin D3-d6; Cholecalciferol-26,26,26,27,27,27-d6; (3S,5Z,7E)-(26,26,26,27,27,27-d6)-9,10-Secocholesta-5,7,10-trien-3-ol; (3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol-d6; Cholecalciferol-d6; Delsterol-d6; Deparal-d6; Ebivit-d6; Oleovitamin D3-d6; Provitina-d6; Ricketon-d6; Videkhol-d6; Vigorsan-d6. Grade: >95%. CAS No. 118584-54-6. Molecular formula: C27H38D6O. Mole weight: 390.67.
Cholecalciferol EP Impurity A
5,6-trans-Vitamin D3 is the major photoisomer of Vitamin D3 analog. Vitamin D3 is a type of vitamin D found to be effective in mediating intestinal calcium absorbtion and bone calcium metabolism. Vitamin D3 is used for the prevention and treatment of vitamin D deficiency and associated disease including rickets, and also used for familial hypophosphatemia, hypoparathyroidism and Fanconi syndrome. Synonyms: (5E,7E)-9,10-secocholesta-5,7,10(19)-trien-3β-ol; trans-cholecalciferol; trans-vitamin D3. Grade: > 95%. CAS No. 22350-41-0. Molecular formula: C27H44O. Mole weight: 384.64.
Cholecalciferol EP Impurity A
Cholecalciferol EP Impurity A. Uses: For analytical and research use. Alternative Names: Vitamin D3 EP Impurity A. CAS No. 22350-41-0. Molecular formula: C27H44O. Mole weight: 384.65. Catalog: APB22350410.
Cholecalciferol EP Impurity B
Cholecalciferol EP Impurity B. Uses: For analytical and research use. Alternative Names: Vitamin D3 EP Impurity B. CAS No. 434-16-2. Molecular formula: C27H44O. Mole weight: 384.65. Catalog: APB434162.
Cholecalciferol EP Impurity C
Cholecalciferol EP Impurity C. Uses: For analytical and research use. Alternative Names: Vitamin D3 EP Impurity C. CAS No. 5226-1-7. Molecular formula: C27H44O. Mole weight: 384.65. Catalog: APB5226017.
Cholecalciferol EP Impurity C
An isomer of Vitamin D3. Cholecalciferol EP Impurity C can used in the preparation of vitamin D analogs. Synonyms: lumisterol 3; (3β,9β,10α)-Cholesta-5,7-dien-3-ol; 9β,10α-Cholesta-5,7-dien-3β-ol. Grade: > 95%. CAS No. 5226-1-7. Molecular formula: C27H44O. Mole weight: 384.64.
Cholecalciferol EP Impurity D
A degradation product of Vitamin D3. It has been shown to stimulate intestinal Ca transport and bone Ca mobilization in anephric rats. Synonyms: iso-Tachysterol 3; Isotachysterol 3; (3β,6E)-9,10-Secocholesta-5(10),6,8(14)-trien-3-ol; (E)-9,10-Secocholesta-5(10),6,8(14)-trien-3β-ol. Grade: 98%. CAS No. 22350-43-2. Molecular formula: C27H44O. Mole weight: 384.64.
Cholecalciferol EP Impurity D (iso-Tachysterol 3)
Cholecalciferol EP Impurity D (iso-Tachysterol 3). Uses: For analytical and research use. Alternative Names: (S)-4-methyl-3-((E)-2-((1R,7aR)-7a-methyl-1-((R)-6-methylheptan-2-yl)-2,3,5,6,7,7a-hexahy dro-1H-inden-4-yl)vinyl)cyclohex-3-en-1-ol. CAS No. 22350-43-2. Molecular formula: C27H44O. Mole weight: 384.64. Catalog: APB22350432.
Cholecalciferol EP Impurity E (Vitamin D3 EP Impurity E)
Cholecalciferol EP Impurity E (Vitamin D3 EP Impurity E). Uses: For analytical and research use. CAS No. 17592-07-3. Molecular formula: C27H44O. Mole weight: 384.65. Catalog: APB17592073.
Cholecalciferol glucuronide
A metabolite of Vitamin D3. Synonyms: (3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-yl β-D-glucopyranosiduronic acid; Vitamin D3 glucosiduronate; Vitamin D3 b-D-Glucuronide. Grade: >95%. CAS No. 57918-08-8. Molecular formula: C33H52O7. Mole weight: 560.76.
Cholecalciferol Impurity 13 (Previtamin D3 )
Cholecalciferol Impurity 13 (Previtamin D3 ). Uses: For analytical and research use. CAS No. 1173-13-3. Molecular formula: C27H44O. Mole weight: 384.65. Catalog: APB1173133.
Cholecalciferol Impurity 14
Cholecalciferol Impurity 14. Uses: For analytical and research use. CAS No. 927822-16-0. Molecular formula: C35H58O2. Mole weight: 510.85. Catalog: APB927822160.
Cholecalciferol Impurity 15
Cholecalciferol Impurity 15. Uses: For analytical and research use. CAS No. 158180-04-2. Molecular formula: C37H62O2. Mole weight: 538.9. Catalog: APB158180042.
Cholecalciferol Impurity 16
Cholecalciferol Impurity 16. Uses: For analytical and research use. Molecular formula: C27H44O. Mole weight: 384.65. Catalog: APB07197.
Cholecalciferol Impurity 18
Cholecalciferol Impurity 18. Uses: For analytical and research use. Molecular formula: C27H44. Mole weight: 368.65. Catalog: APB07198.
Cholecalciferol Impurity 19
Cholecalciferol Impurity 19. Uses: For analytical and research use. CAS No. 89231-90-3. Molecular formula: C27H44O2. Mole weight: 400.65. Catalog: APB89231903.
Cholecalciferol Impurity 21 (Vitamin D3 Impurity 21). Uses: For analytical and research use. CAS No. 156965-15-0. Molecular formula: C32H48O5. Mole weight: 512.73. Catalog: APB156965150.
Cholecalciferol sulfate Sodium Salt
The main metabolite of Vitamin D3. It has potent biological activity. Vitamin D3-sulfate had <5% of the activity of vitamin D3 to mobilize Ca from bone and.apprx.1% of the ability of Vitamin D3 to stimulate Ca transport, elevate serum P, or support bone calcification. Synonyms: Vitamin D3 Sulfate Sodium Salt; (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-Dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylenecyclohexanol Sodium Salt; (3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol Ηydrogen Sulfate Sodium Salt. Grade:> 95%. CAS No. 78392-27-5. Molecular formula: C27H44O4S`Na. Mole weight: 464.71 23.
Vitamin D3 is cholecalciferol, one of the vitamin D family. Vitamin D3 has been used to prevent and treat breast cancer, prostate and possibly other cancers and Vitamin D3 is essential to maintain bone density. Vitamin D3 is necessary for the ultilization of Calcium and Phosphorus, and for the assimilation of Vitamin A. It also has a strong immune enhancing effect. In many ways vitamin D acts as a hormone and is potent in minute quantities. One microgram of cholecalciferol has 40 IU of vitamin D activity. Vitamin D is necessary for utilization of calcium and phosphorus. Activated 7-dehydrocholesterol, cholecalciferol, also called activated 7-dehydrocholesterol, cholecalciferol. The biologically active form of Vitamin D. It is transported by the blood and the liver converts it to 25-Hydroxycholecalciferol (25-Hydroxyvitamin D, Calcidiol) which is converted in the kidneys to 1, 25-Di hydroxycholecalciferol (1,25-Dihydroxyvitamin D, Calcitriol). Group: Biochemicals. Alternative Names: Vitamin D3; Activated 7-dehydrocholesterol. Grades: Cell Culture Grade. CAS No. 67-97-0. Pack Sizes: 1g, 5x1g. US Biological Life Sciences.
Cholecystokinin is a peptide hormone. Cholecystokinin, as a hunger suppressant, inhibits food intake and stimulates the digestion of fat and protein. Cholecystokinin can be used for the research of gastrointestinal system[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cholecystokinin-33(human); CCK-33(human). CAS No. 9011-97-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2932.
Cholecystokinin-33 (human)
Cholecystokinin-33 (human) is a peptide hormone, holding great significance in biomedical research as it enables exploration into the intricacies of cholecystokinin receptors. Synonyms: CCK-39 (7-39) (human); H-Lys-Ala-Pro-Ser-Gly-Arg-Met-Ser-Ile-Val-Lys-Asn-Leu-Gln-Asn-Leu-Asp-Pro-Ser-His-Arg-Ile-Ser-Asp-Arg-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2; L-lysyl-L-alanyl-L-prolyl-L-seryl-glycyl-L-arginyl-L-methionyl-L-seryl-L-isoleucyl-L-valyl-L-lysyl-L-asparagyl-L-leucyl-L-glutaminyl-L-asparagyl-L-leucyl-L-alpha-aspartyl-L-prolyl-L-seryl-L-histidyl-L-arginyl-L-isoleucyl-L-seryl-L-alpha-aspartyl-L-arginyl-L-alpha-aspartyl-O4-sulfo-L-tyrosyl-L-methionyl-glycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamide. Grade: ≥90%. CAS No. 96827-04-2. Molecular formula: C167H263N51O52S4. Mole weight: 3945.44.
Cholenic acid
Cholenic acid. Alternative Names: 3β-hydroxychol-5-en-24-oic acid. CAS No. 5255-17-4. Purity: >99%. Product ID: ALCFA5255174. Molecular formula: C24H38O3. Mole weight: 374.56. Alfa Chemistry - ISO 9001:32057 Certified.
cholenic acid-d4
cholenic acid-d4. Alternative Names: 5β-hydroxychol-5-en-24-oic acid-d4. CAS No. 2770684-32-5. Purity: >99%. Product ID: ALCFA2770684325. Molecular formula: C24H34D4O3. Mole weight: 378.59. Alfa Chemistry - ISO 9001:32057 Certified.
Cholera autoinducer 1
Cholera autoinducer 1 is Vibrio cholerae autoinducer (S)-3-hydroxytridecan-4-one. Cholera autoinducer 1 influences chemotaxis in C. elegans[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CAI-1. CAS No. 1004296-82-5. Pack Sizes: 1 mg. Product ID: HY-145376.
Cholera toxin B subunit, from vibrio cholerae
Cholera toxin B subunit, from vibrio cholerae (CTB, from vibrio cholerae) is non-toxic to cells and possesses no intrinsic adenylate cyclase activity. Cholera toxin B subunit, from vibrio cholerae attaches to cells by binding to ganglioside GM1.8 CTB has been shown to be a good label for microglial cells (due to the enrichment of ganglioside GM1 on their cell surface), but not for oligodendrocytes or astrocytes. Cholera toxin B subunit, from vibrio cholerae has been reported to be an excellent tracer for the study of axonal transport using immunohistochemical methods. Cholera toxin B subunit, from vibrio cholerae has been widely used as a marker of membrane lipid rafts[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CTB, from vibrio cholerae. CAS No. 131096-89-4. Pack Sizes: 500 μg; 1 mg. Product ID: HY-P3394.
Cholessteryl Oleyl Carbonate
Viscous, white liquid or mass, 99%. CAS No. 17110-51-9. Pack Sizes: Typically in stock: 25g, 100g. Mole weight: 681.14. MP/BP: M.P. 18 (Ch), 32 (I). Order No: FR-0423.
This enzyme, found in several bacterial pathogens, is involved in degradation of the host cholesterol. It catalyses the hydroxylation of the C-26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate, initiating the degradation of the alkyl side-chain of cholesterol. The products are exclusively in the (25R) conformation. The enzyme also accepts cholesterol as a substrate. cf. EC 1.14.13.141, cholest-4-en-3-one 26-monooxygenase. The enzyme can receive electrons from ferredoxin reductase in vitro, its natural electron donor is not known yet. Group: Enzymes. Synonyms: CYP142. Enzyme Commission Number: EC 1.14.13.221. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0824; cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming]; EC 1.14.13.221; CYP142. Cat No: EXWM-0824.
This enzyme, found in several bacterial pathogens, is involved in degradation of the host's cholesterol. It catalyses the hydroxylation of the C-26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate, initiating the degradation of the alkyl side-chain of cholesterol. The products are exclusively in the (25S) configuration. It is a two-component system consisting of a P-450 (heme thiolate) oxygenase (Cyp125) and a ferredoxin reductase (most likely KshB, which is also a part of EC 1.14.13.142, 3-ketosteroid 9α-monooxygenase). The enzyme also accepts cholesterol as a substrate. cf. EC 1.14.13.221, cholest-4-en-3-one 27-monooxygenase. Group: Enzymes. Synonyms: CYP125; CYP125A1; cholest-4-en-3-one 27-monooxygenase (misleading); cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxyl. Enzyme Commission Number: EC 1.14.13.141. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0741; cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]; EC 1.14.13.141; CYP125; CYP125A1; cholest-4-en-3-one 27-monooxygenase (misleading); cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxylating); cholest-4-en-3-one 26-monooxygenase (ambiguous). Cat No: EXWM-0741.
Cholest-5-en-3-b-yl octadecanoate. Group: Biochemicals. Alternative Names: Cholesteryl stearate. Grades: Highly Purified. CAS No. 35602-69-8. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C45H80O2. US Biological Life Sciences.
Worldwide
Cholest-5-en-3-ol, 3-CEphosphoramidite
Cholest-5-en-3-ol, 3-CEphosphoramidite, a versatile phosphoramidite reagent, is vital for modifying RNA and DNA analogs. Its immense value lies in its ability to assist in the treatment of varied afflictions including cancer, HIV, and genetic defects, making it a pivotal cog in the biomedical industry. Respected chemical suppliers globally procure and make it available. CAS No. 143723-63-1.
cholest-5-ene-3β,7α-diol 3β-dehydrogenase
Highly specific for 3β-hydroxy-C27-steroids with Δ5-double bond. Group: Enzymes. Synonyms: 3β-hydroxy-Δ5-C27-steroid oxidoreductase. Enzyme Commission Number: EC 1.1.1.181. CAS No. 56626-16-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0084; cholest-5-ene-3β,7α-diol 3β-dehydrogenase; EC 1.1.1.181; 56626-16-5; 3β-hydroxy-Δ5-C27-steroid oxidoreductase. Cat No: EXWM-0084.
Cholesta-3,5-diene
Cholesta-3,5-diene is an inflammatory modulator that targets immune cells such as neutrophils and accelerates wound healing by promoting neutrophil chemotaxis and fibroblast migration. Cholesta-3,5-diene enhances immune cell recruitment and extracellular matrix deposition by activating chemokine receptor-mediated signaling pathways such as PI3K/Akt. Cholesta-3,5-diene can be applied topically to wound repair and has potential therapeutic value in chronic ulcers or skin lesions[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: delta-3,5-Cholestadiene. CAS No. 747-90-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W127575.
cholestanetriol 26-monooxygenase
This mitochondrial cytochrome P-450 enzyme requires adrenodoxin. It catalyses the first three sterol side chain oxidations in bile acid biosynthesis via the neutral (classic) pathway. Can also act on cholesterol, cholest-5-ene-3β,7α-diol, 7α-hydroxycholest-4-en-3-one, and 5β-cholestane-3α,7α-diol. The enzyme can also hydroxylate cholesterol at positions 24 and 25. The initial source of the electrons is NADPH, which transfers the electrons to the adrenodoxin via EC 1.18.1.6, adrenodoxin-NADP+ reductase. Group: Enzymes. Synonyms: 5β-cholestane-3α,7α,12α-triol 26-hydroxylase; 5β-cholestane-3α,7α,12α-triol hydroxylase; cholestanetriol 26-hydroxylase; sterol 27-hydroxylase; sterol 26-hydroxylase; cholesterol 27-hydroxyla. Enzyme Commission Number: EC 1.14.15.15. CAS No. 52227-77-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0940; cholestanetriol 26-monooxygenase; EC 1.14.15.15; 52227-77-7; 5β-cholestane-3α,7α,12α-triol 26-hydroxylase; 5β-cholestane-3α,7α,12α-triol hydroxylase; cholestanetriol 26-hydroxylase; sterol 27-hydroxylase; sterol 26-hydroxylase; cholesterol 27-hydroxylase; CYP27A; CYP27A1; cytochrome P450 27A1'. Cat No: EXWM-0940.
cholestenoic acid-d5. Alternative Names: 3β-hydroxy-5-cholestenoic acid-d5. CAS No. 1620239-03-3. Purity: >99%. Product ID: ALCFA1620239033. Molecular formula: C27H39D5O3. Mole weight: 421.667. Alfa Chemistry - ISO 9001:32057 Certified.
cholestenol Δ-isomerase
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. This enzyme participates in biosynthesis of steroids. Group: Enzymes. Enzyme Commission Number: EC 5.3.3.5. CAS No. 52410-46-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5502; cholestenol Δ-isomerase; EC 5.3.3.5; 52410-46-5. Cat No: EXWM-5502.
Cholestenone
Cholestenone (4-cholesten-3-one) is an orally available antimicrobial agent that is metabolized primarily in the liver as an intermediate oxidation product of cholesterol. Cholestenone inhibits human dermal fibroblast migration and fights Helicobacter pylori infection in vitro and in mouse models by inhibiting cholesterol-α-D-glucopyranoside (CGL). Cholestenone also alleviates metabolic disorders caused by obesity in db/db mice[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Cholesten-3-one. CAS No. 601-57-0. Pack Sizes: 250 mg; 500 mg. Product ID: HY-113365.
Cholestenone-d5
Cholestenone-d5 is the deuterium labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Cholesten-3-one-d5. CAS No. 72560-60-2. Pack Sizes: 1 mg; 5 mg; 25 mg. Product ID: HY-113365S.
Cholesterol(Cholesterin) is the principal sterol of all higher animals required to build and maintain membranes. Group: Inhibitors. Alternative Names: Cholesterin. CAS No. 57-88-5. Pack Sizes: 50mg. Product ID: S4154. Formula: C27H46O. Smiles: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Cholesterol
Cholesterol is a natural waxy substance that is found in human skin and is also commonly used in cosmetics and skincare products. In cosmetics, cholesterol is used as a moisturizer and emollient to help soften and smooth the skin, as well as to improve the appearance of fine lines and wrinkles. It is also believed to help strengthen the skin's barrier function and protect against environmental damage. The chemical formula of cholesterol is C27H46O, and it typically appears as a white or off-white powder or solid. It is also available in liquid form, often in combination with other ingredients. Alternative Names: 3β-Hydroxycholest-5-ene. CAS No. 57-88-5. Purity: 98%. Product ID: CI-SC-0563. Molecular formula: C27H46O. Mole weight: 386.66 g/mol. IUPAC Name: (3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol. Canonical SMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C. Alfa Chemistry - ISO 9001:32057 Certified.
100g Pack Size. Group: Biochemicals. Formula: C27H46O. CAS No. 57-88-5. Prepack ID 13575167-100g. Molecular Weight 386.65. See USA prepack pricing.
Cholesterol
500g Pack Size. Group: Biochemicals. Formula: C27H46O. CAS No. 57-88-5. Prepack ID 13575167-500g. Molecular Weight 386.65. See USA prepack pricing.
Cholesterol
Cholesterol occurs as white or faintly yellow, almost odorless, pearly leaflets, needles, powder, or granules. On prolonged exposure to light and air, cholesterol acquires a yellow to tan color. Synonyms: Cholesterin; cholesterolum. CAS No. 57-88-5. Product ID: PE-0519. Molecular formula: C27H46O. Mole weight: 386.67. Category: Emollient; Emulsifying Agents. Product Keywords: Excipients for Liquid Dosage Form; Emulsifier Excipients; PE-0519; Cholesterol; Emollient; Emulsifying Agents; C27H46O; 57-88-5. UNII: 97C5T2UQ7J. Chemical Name: Cholest-5-en-3β-ol. Grade: Pharmceutical Excipients. Administration route: Injections; ophthalmic, topical, and vaginal. Dosage Form: Injections; ophthalmic, topical, and vaginal preparations. Stability and Storage Conditions: Cholesterol is stable and should be stored in a well-closed container, protected from light. Source and Preparation: The commercial material is normally obtained from the spinal cord of cattle by extraction with petroleum ethers, but it may also be obtained from wool fat. Purification is normally accomplished by repeated bromination. Cholesterol may also be produced by entirely synthetic means. Cholesterol produced from animal organs will always contain cholestanol and other saturated sterols. Applications: Cholesterol is used in cosmetics and topical pharmaceutical formulations at concentrations of 0.3-5.0% w/w as an emulsifying agent. It imparts water-absorbi
Cholesterol-13C2 is the 13C labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins[1][2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 78887-48-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0322S5.
Cholesterol-13C5
Cholesterol-13C5. Alternative Names: Cholesterol-13C5;[23,24,25,26,27-13C5]Cholesterol. CAS No. 150044-24-9. Product ID: ACM150044249. Molecular formula: C27H46O. Mole weight: 391.62. Alfa Chemistry - ISO 9001:32057 Certified.
Cholesterol-[13C5]
Cholesterol-[13C5], is the labeled analogue of Cholesterol. Cholesterol is biosynthesized by all animal cells and is an essential structural component of animal cell membranes. Uses: [13c] cholesterol can be used as a practical tracer for studies of cholesterol metabolism in humans. Synonyms: Cholesterol-13C5; Cholesterol-23,24,25,26,27-13C5; (3β)-Cholest-5-en-3-ol-13C5; (-)-Cholesterol-13C5; 3β-Hydroxycholest-5-ene-13C5; Cholest-5-en-3β-ol-13C5; Cholesterin-13C5; Cholesteryl-13C5 alcohol; Dythol-13C5; Lidinite-13C5; NSC 8798-13C5; Provitamin D-13C5; 5-Cholesten-3β-ol-13C5. Grade: ≥98% by CP; ≥99% atom 13C. CAS No. 150044-24-9. Molecular formula: C22[13C]5H46O. Mole weight: 391.62.
Cholesterol-[2,2,3,4,4,6-d6] is the labelled analogue of Cholesterol. Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especially in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones. Synonyms: Cholesterol-2,2,3,4,4,6-d6; Cholesterol-d6; (3β)-Cholest-5-en-3-ol-d6; (-)-Cholesterol-d6; 3β-Hydroxycholest-5-ene-d6; 5:6-Cholesten-3β-ol-d6; Cholest-5-en-3β-ol-d6; Cholesterin-d6; Cholesteryl-d6 Alcohol; Dythol-d6; Lidinit-d6; Lidinite-d6; NSC 8798-d6; Provitamin D-d6; 5-Cholesten-3β-ol-d6. Grade: 98% by CP; 97% atom D. CAS No. 92543-08-3. Molecular formula: C27H40D6O. Mole weight: 392.69.
Cholesterol-2,2,3,4,4,6-d6
Cholesterol-2,2,3,4,4,6-d6. Group: Biochemicals. Grades: Highly Purified. CAS No. 92543-08-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C27D6H40O. US Biological Life Sciences.
Worldwide
Cholesterol-2,2,4,4,6-D5
Cholesterol-2,2,4,4,6-D5. Product ID: ACMA00005202. Alfa Chemistry - ISO 9001:32057 Certified.
A P-450 heme-thiolate protein. The enzyme can also produce 25-hydroxycholesterol. In addition, it can further hydroxylate the product to 24,25-dihydroxycholesterol and 24,27-dihydroxycholesterol. This reaction is the first step in the enzymic degradation of cholesterol in the brain as hydroxycholesterol can pass the blood-brain barrier whereas cholesterol cannot. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: cholesterol 24-monooxygenase; CYP46; CYP46A1; cholesterol 24S-hydroxylase; cytochrome P450 46A1. Enzyme Commission Number: EC 1.14.14.25. CAS No. 50812-30-1, 213327-78-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0922; cholesterol 24-hydroxylase; EC 1.14.14.25; 50812-30-1, 213327-78-7; cholesterol 24-monooxygenase; CYP46; CYP46A1; cholesterol 24S-hydroxylase; cytochrome P450 46A1. Cat No: EXWM-0922.
Cholesterol 24-hydroxylase-IN-1
Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective cholesterol 24-hydroxylase (CH24H or CYP46A1) inhibitor (IC50=8.5 nM). Cholesterol 24-hydroxylase-IN-1 can cross blood-brain barrier[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1613480-70-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144309.
Cholesterol-[25,26,26,26,27,27,27-d7]
Cholesterol-[25,26,26,26,27,27,27-d7] is the labelled analogue of Cholesterol. Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especially in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones. Synonyms: Cholesterol-25,26,26,26,27,27,27-d7; Cholesterol-d7; (3β)-Cholest-5-en-3-ol-d7; (-)-Cholesterol-d7; 3β-Hydroxycholest-5-ene-d7; 5:6-Cholesten-3β-ol-d7; Cholest-5-en-3β-ol-d7; Cholesterin-d7; Cholesteryl-d7 alcohol-d7; Dythol-d7; Lidinit-d7; NSC 8798-d7; Provitamin D-d7; 5-Cholesten-3β-ol-d7. Grade: 98% by CP; 97% atom D. CAS No. 83199-47-7. Molecular formula: C27H39D7O. Mole weight: 393.71.
Cholesterol-[25,26,27-13C3]
Cholesterol-[25,26,27-13C3], is the labelled analogue of Cholesterol. Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especially in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones. Synonyms: Cholesterol-25,26,27-13C3. Grade: 99% by CP; 99% atom 13C. CAS No. 335080-97-2. Molecular formula: C24[13C]3H46O. Mole weight: 389.63.
cholesterol 25-hydroxylase
Unlike most other sterol hydroxylases, this enzyme is not a cytochrome P-450. Instead, it uses diiron cofactors to catalyse the hydroxylation of hydrophobic substrates. The diiron cofactor can be either Fe-O-Fe or Fe-OH-Fe and is bound to the enzyme through interactions with clustered histidine or glutamate residues. In cell cultures, this enzyme down-regulates cholesterol synthesis and the processing of sterol regulatory element binding proteins (SREBPs). Group: Enzymes. Synonyms: cholesterol 25-monooxygenase. Enzyme Commission Number: EC 1.14.99.38. CAS No. 60202-07-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1049; cholesterol 25-hydroxylase; EC 1.14.99.38; 60202-07-5; cholesterol 25-monooxygenase. Cat No: EXWM-1049.
Cholesterol-[26,26,26,27,27,27-d6], is the labelled analogue of Cholesterol. Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especially in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones. Synonyms: Cholesterol-26,26,26,27,27,27-d6; (26,26,26,27,27,27-2H6)Cholesterol. Grade: 97% by CP; 98% atom D. CAS No. 60816-17-3. Molecular formula: C27H40D6O. Mole weight: 392.69.