A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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| Product | Description | |
|---|---|---|
| Chrysin | Chrysin is a flavonoid with anti-inflammatory, antioxidant and antitumor effects. Chrysin is a central benzodiazepine receptor ligand that has potential anxiolytic activity. It blocks COX-2 gene expression, PGE2 production, and hydroxyl radical formation in LPS-induced RAW 264.7 cells. Chrysin is a natural compound found in the barks of Oroxylum indicum, it can be used in cosmetics material. Uses: Ingredient of health care products. Synonyms: 57Dihydroxyflavone; NP005901; NP 005901; NP-005901; Galangin flavanone. 5,7-Dihydroxyflavone; Chrysine; 5,7-Dihydroxy-2-phenyl-4H-chromen-4-one; Crysin. Grade: ≥ 98%. CAS No. 480-40-0. Molecular formula: C15H10O4. Mole weight: 254.241. |  |
| Chrysin | Chrysin is one of the most well known estrogen blockers. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5,7-Dihydroxyflavone. CAS No. 480-40-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-14589. |  |
| Chrysin | 25g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C15H10O4. CAS No. 480-40-0. Prepack ID 90027484-25g. Molecular Weight 254.24. See USA prepack pricing. |  |
| Chrysin | Chrysin. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100g, 250g, 25g, 1Kg. US Biological Life Sciences. |  Worldwide |
| Chrysin 7-glucuronide | Formula: Group: Biochemicals. Grades: Plant Grade. CAS No. 35775-49-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Chrysocauloflavone I | Chrysocauloflavone I, an unfrequent biflavonoid, is purified from Selaginella doederleinii. Grade: 98.0%. CAS No. 899789-51-6. Molecular formula: C30H20O10. Mole weight: 540.48. | |
| Chrysoeriol | Chrysoeriol is a natural compound isolated from the herbs of Medicago sativa. Chrysoeriol can potently inhibit the induction of nitric oxide synthase by blocking activator protein 1 (AP-1) activation and its anti-inflammatory effects. Chrysoeriol can induce nod genes in rhizobium meliloti. Chrysoeriol can inhibit the downstream signal transduction pathways of platelet-derived growth factor (PDGF)-Rbeta, including ERK1/2, p38, and Akt phosphorylation, which suggests that chrysoeriol may be used for the prevention and treatment of vascular diseases during restenosis after coronary angioplasty. Synonyms: 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; 4',5,7-Trihydroxy-3'-methoxyflavone; 3'-Methoxy-4',5,7-trihydroxyflavone; 3'-Methoxyapigenin; 3'-O-Methylluteolin; 5,7,4'-Trihydroxy-3'-methoxyflavone; Chrysoriol; Luteolin 3'-Methyl Ether; Scoparol; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-. Grade: 98.0%. CAS No. 491-71-4. Molecular formula: C16H12O6. Mole weight: 300.27. | |
| Chrysoeriol | Chrysoeriol Inhibitor. Uses: Scientific use. Product Category: TN1490. CAS No. 491-71-4. |  |
| Chrysoeriol | Chrysoeriol is a kind of natural yellow ash, which can be used for heating plants Coronopus didymus. Chrysoeriol suppresses the JAK2/STAT3, IκB/p65, and NF-κB pathways, and has strong anti-inflammatory activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 491-71-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-121471. | |
| Chrysoeriol | A methoxyflavonoid that selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cells. A metabolite of Luteolin. Group: Biochemicals. Alternative Names: 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; 4',5,7-Trihydroxy-3'-methoxyflavone; 3'-Methoxy-4',5,7-trihydroxyflavone; 3'-Methoxyapigenin; 3'-O-Methylluteolin; 5,7,4'-Trihydroxy-3'-methoxyflavone; Chrysoriol; Luteolin 3'-Methyl Ether. Grades: Highly Purified. CAS No. 491-71-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??O?, Molecular Weight: 300.26. US Biological Life Sciences. | Worldwide |
| Chrysoeriol-7-O-beta-D-glucopyranoside | Botanical Source: Group: Biochemicals. Alternative Names: Thermopsoside. Grades: Plant Grade. CAS No. 19993-32-9. Pack Sizes: 5mg, 10mg. US Biological Life Sciences. | Worldwide |
| Chrysoidine-[13C6] | Chrysoidine-[13C6] is the labelled analogue of Chrysoidine, which is a yellow-orange crystalline dye. Synonyms: Chrysoidine-13C6; 4-Phenyl-13C6-azo-1,3-phenylenediamine; Chrysoidine G-13C6; Chrysoidine Y-13C6; Solvent Orange 3-13C6; Basic Orange 2-13C6; Basic Orange 2100-13C6. Grade: 95% by HPLC; 98% atom 13C. Molecular formula: C6[13C]6H13ClN4. Mole weight: 254.71. | |
| Chrysomycin A | Chrysomycin A is a C-glycoside antitumor antibiotic isolated from Streptomyces, and it is an inhibitor of the catalytic activity of human topoisomerase II. It has effective antibacterial, antifungal, antiviral and antitumor activities. It may act as a light-activated cross-linking agent between DNA and histones. Synonyms: Chrysomycin V; Virenomycin V; Albacarcin V. Grade: >99% by HPLC. CAS No. 82196-88-1. Molecular formula: C28H28O9. Mole weight: 508.51. | |
| Chrysomycin B | Chrysomycin B is a minor analogue in a complex of C-glycoside antitumor active substances isolated from Streptomyces. Its activity is lower than that of its vinyl analogue (Chrysomycin A), but it still has strong anti-tumor activity and is an inhibitor of the catalytic activity of human topoisomerase II. It can be used as a light-activated cross-linking agent for DNA and histones. Synonyms: Chrysomycin M; Virenomycin M; Albacarcin M. Grade: >98% by HPLC. CAS No. 83852-56-6. Molecular formula: C27H28O9. Mole weight: 496.50. | |
| Chrysophanein | Chrysophanein is a chrysophanol glycoside from leaves and roots of Aloe hijazensis. Chrysophanein shows a moderate cytotoxic activity against several carcinoma cells lines[1]. Uses: Scientific research. Category: Natural products. CAS No. 4839-60-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N4151. | |
| Chrysophanic acid | Chrysophanic acid. Group: Biochemicals. Alternative Names: 1,8-Dihydroxy-3-methyl-9,10-anthracenedione; 1,8-Dihydroxy-3-methylanthraquinone; 3-Methylchrysazin. Grades: Highly Purified. CAS No. 481-74-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C15H10O4. US Biological Life Sciences. | Worldwide |
| Chrysophanol | Chrysophanol. Group: Biochemicals. Alternative Names: Chrysophanic acid; 1,8-Dihydroxy-3-methylanthraquinone. Grades: Plant Grade. CAS No. 481-74-3. Pack Sizes: 20mg. Molecular Formula: C15H10O4, Molecular Weight: 254.238. US Biological Life Sciences. | Worldwide |
| Chrysophanol | Chrysophanic acid (Chrysophanol) is a natural anthraquinone with anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells. Chrysophanic acid preferentially blocked proliferation in SNU-C5 cells but not in other cell lines (HT7, HT29, KM12C, SW480, HCT116 and SNU-C4) with low levels of EGFR expression. Chrysophanic acid treatment in SNU-C5 cells inhibited EGF-induced phosphorylation of EGFR and suppressed activation of downstream signaling molecules, such as AKT, extracellular signal-regulated kinase (ERK) and the mammalian target of rapamycin (mTOR)/ribosomal protein S6 kinase (p70S6K). Chrysophanic acid (80 and 120 μm) significantly blocked cell proliferation when combined with the mTOR inhibitor, rapamycin. These findings offer the first evidence of anticancer activity for chrysophanic acid via EGFR/mTOR mediated signaling transduction pathway. Chrysophanol is a natural compound found in the roots and rhizomes of Rheum palmatum L. It can be used in cosmetics material. Uses: Anti-inflammatory. Synonyms: 1,8-dihydroxy-3-methylanthracene-9,10-dione. Grade: ≥ 98 %. CAS No. 481-74-3. Molecular formula: C15H10O4. Mole weight: 254.24. | |
| Chrysophanol | Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Chrysophanic acid. CAS No. 481-74-3. Pack Sizes: 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-13595. | |
| Chrysophanol 1-O-glucoside | Chrysophanol 1-O-glucoside, an inherent component of diverse botanical species, boasts of paramount attention for its noteworthy anti-inflammatory and anti-tumor potentialities that have long been professed in traditional medicine. Its multifaceted pharmacological abilities have been under the researchers' radar, warranting potential deployment in treating metabolic maladies, liver afflictions, and obesity. Besides, this natural compound may stimulate the food and cosmetics industries with its remarkable antioxidant traits. Synonyms: 8-hydroxy-3-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanthracene-9,10-dione; Chrysophanol 1-glucoside. Grade: >98%. CAS No. 4839-60-5. Molecular formula: C21H20O9. Mole weight: 416.382. | |
| Chrysophenine | Chrysophenine. Group: Biochemicals. Alternative Names: Direct Yellow 12; CI 24895. Grades: Highly Purified. CAS No. 2870-32-8. Pack Sizes: 100g, 250g, 500g, 1kg. US Biological Life Sciences. | Worldwide |
| Chrysophsin-1 | Chrysophsin-1 is from Pagrus major. It has antibacterial activity against Gram-positive bacteria B.subtilis, L.garvieae and S.iniae F-8502, and Gram-negative bacteria E.coli WT-2, V.anguillarum, V.penaeicida KHA, V.harveyi, V.vulnificus, A.salmonicida NCMB 1102 and P.putida. Chrysophsin-1 also has hemolytic activity against human red blood cells. | |
| Chrysophsin-2 | Chrysophsin-2 is from Pagrus major. It has antibacterial activity against Gram-positive bacteria B.subtilis, L.garvieae and S.iniae F-8502, and Gram-negative bacteria E.coli WT-2, V.anguillarum, V.penaeicida KHA, V.harveyi, V.vulnificus and A.salmonicida NCMB 1102. Chrysophsin-2 also has hemolytic activity against human red blood cells. | |
| Chrysophsin-3 | Chrysophsin-3 is from Pagrus major. It has antibacterial activity against Gram-positive bacteria B. subtilis, L. garvieae and S. iniae F-8502, and Gram-negative bacteria E. coli WT-2, V. anguillarum, V. penaeicida KHA, V. harveyi, V. vulnificus, A. salmonicida NCMB 1102 and P. putida. Chrysophsin-3 has hemolytic activity against human red blood cells. | |
| Chrysospermin A | It is produced by the strain of Apiocrea chrysosperma Ap101. Chrysospermin A has antibacterial activities against individual gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis), Klebsiella pneumoniae and individual yeasts (Ocher echinoderma, saccharomyces cerevisiae). CAS No. 160824-57-7. Molecular formula: C90H140N22O23. Mole weight: 1898.20. | |
| Chrysospermin B | It is produced by the strain of Apiocrea chrysosperma Ap101. Chrysospermin B has antibacterial activities against individual gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis), Klebsiella pneumoniae and individual yeasts (Ocher echinoderma, saccharomyces cerevisiae). Molecular formula: C91H142N22O23. Mole weight: 1912.23. | |
| Chrysospermin C | It is produced by the strain of Apiocrea chrysosperma Ap101. Chrysospermin C has antibacterial activities against individual gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis), Klebsiella pneumoniae and individual yeasts (Ocher echinoderma, saccharomyces cerevisiae). Molecular formula: C91H142N22O23. Mole weight: 1912.23. | |
| Chrysospermin D | It is produced by the strain of Apiocrea chrysosperma Ap101. Chrysospermin D has antibacterial activities against individual gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis), Klebsiella pneumoniae and individual yeasts (Ocher echinoderma, saccharomyces cerevisiae). Molecular formula: C91H144N22O23. Mole weight: 1914.24. | |
| Chrysosplenetin | Chrysosplenetin is a flavonoid isolated from the herbs of Laggera pterodonta, which is a metabolic inhibitor of artemisinin. Uses: Anti-enterovirus 71. Synonyms: Chrysosplenetin B; 3,6,7,3'-Tetramethylquercetagetin; 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one; EMD-20940; 4H-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxy-. Grade: 99%. CAS No. 603-56-5. Molecular formula: C19H18O8. Mole weight: 374.4. | |
| Chrysosplenetin | Chrysosplenetin is an orally active polymethoxyflavone. Chrysosplenetin exerts anticancer effects by inhibiting topoisomerase, protecting DNA and inducing apoptosis. Chrysosplenetin acts as an antimalarial sensitizer, reverses Artemisinin (HY-B0094) resistance by inhibiting and downregulating P-glycoprotein, and enhances the efficacy of Artemisinin. Chrysosplenetin promotes bone formation by activating the Wnt/β-catenin pathway and exerts anti-osteoporotic effects[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 603-56-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-N1457. | |
| Chrysosplenol C | Chrysosplenol C is a trimethoxyflavone that is the 3,7,3'-trimethyl ether derivative of quercetagetin. It has a role as an antineoplastic agent and an antiviral agent. Synonyms: Quercetagetin 3,7,3'-trimethyl ether; 3,7,3'-trimethylquercetagetin. Grade: 98%. CAS No. 23370-16-3. Molecular formula: C18H16O8. Mole weight: 360.32. | |
| CHRYSOSPLENOLD | Chrysosplenol D isolated from the herbs of Artemisia annua L. Uses: Antibiotics and antimalarials. Synonyms: 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,6,7-trimethoxychromen-4-one. Grade: 98.5%. CAS No. 14965-20-9. Molecular formula: C18H16O8. Mole weight: 360.3. | |
| CHS-828 | CHS-828 (GMX1778) is a competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), with an IC50 less than 25 nM. CHS-828 (GMX1778) exerts a cytotoxic effect by decreasing the cellular level of NAD+ and exhibits a potent anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GMX1778. CAS No. 200484-11-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10079. | |
| CHS-828 | Antitumor compound. Programmed cell death inducer. Cytotoxic. Antiproliferative. p53 activator. IkappaB kinase inhibitor. NF-kappaB inhibitor. Nampt/visfatin inhibitor. Group: Biochemicals. Alternative Names: GMX1778, (E)-1--2-cyano-3-(pyridin-4-yl)guanidine. Grades: Highly Purified. CAS No. 200484-11-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C19H22ClN5O. US Biological Life Sciences. | Worldwide |
| CHS-828 | CHS-828 is a synthetic guanidine-based small anticancer molecule. CHS 828 was found to exert potent cytotoxic effects in human breast and lung cancer cell lines, with lesser effects on normal fibroblasts and endothelial cells. In nude mice bearing human tumor xenografts, CHS 828, at doses from 20 to 50 mg/kg/day p.o., inhibited the growth of MCF-7 breast cancer tumors and caused regression of NYH small cell lung cancer tumors. Oral administration of CHS 828 once weekly improved efficacy without increasing toxicity. CHS 828 was found to compare favorably with established chemotherapeutic agents such as cyclophosphamide, etoposide, methotrexate, and paclitaxel. In mice with NYH tumors, long-term survival (>6 months) was observed after treatment with CHS 828 was stopped. CHS 828 is an effective new antitumor agent, with a potentially new mechanism of action. CHS-828 appeared to kill cancer cells by depleting NAD. CHS 828 is presently being tested in Phase I clinical trials in collaboration with the European Organization for Research and Treatment of Cancer. Synonyms: CHS 828; CHS828; CHS-828; GMX-1778; GMX1778; GMX 1778. CAS No. 200484-11-3. Molecular formula: C19H22ClN5O. Mole weight: 371.869. | |
| Chst15-IN-1 | Chst15-IN-1 is a potent reversible covalent Chst15 inhibitor. Chst15-IN-1 effectively inhibits chondroitin sulfate-E (CS-E) sulfation levels and other closely related glycosaminoglycans (GAG) sulfotransferases. Chst15-IN-1, as a selective sulfotransferase inhibitor, can diminish the inhibitory effects of chondroitin sulfate proteoglycans (CSPGs), and can be used for the stimulation of neuronal repair[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2158198-77-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124704. | |
| Chuangxinmycin | Chuangxinmycin is produced by the strain of Actinoplanes jinanensis. It has activities against Staphylococcus aureus, Haemophilus influenzae, Escherichia coli and Shigella laminae. Synonyms: Chuanghsinmycin; (-)-chuangxinmycin; cis-(-)-3,5-Dihydro-3-methyl-2H-thiopyrano(4,3,2-cd)indole-2-carboxylic acid. CAS No. 63339-68-4. Molecular formula: C12H11NO2S. Mole weight: 233.29. | |
| Chuchuhuasi Bark Powder (Peru) | Chuchuhuasi Bark Powder (Peru). |  CA, FL & NJ |
| CHU N6 VITAMIN SOL. (1000x) | CHU N6 VITAMIN SOL. (1000x). Product ID: ACMA00011419. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| CHU N6 VITAMIN SOLUTION (1000X) | CHU N6 VITAMIN SOLUTION (1000X). Product ID: ACMA00011318. Alfa Chemistry - ISO 9001:32057 Certified. | |
| CHU'S N6 BASAL MED. W/ VITAMIN | CHU'S N6 BASAL MED. W/ VITAMIN. Product ID: ACMA00011418. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Chute Lining | Chute Lining. |  |
| ChX710 | ChX710 efficiently primed cellular response to transfected plasmid DNA as assessed by potent synergistic effects on IFN-β secretion and ISG expression levels. This cellular response was dependent on STING. Synonyms: N-(1-(Dimethylamino)propan-2-yl)-2-(pyridin-4-yl)-1H-benzo[d]imidazole-7-carboxamide. Grade: 98%. CAS No. 2438721-44-7. Molecular formula: C18H21N5O. Mole weight: 323.39. | |
| chymase | In mast cell granules. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase, chymase; skeletal muscle (SK) protease. Enzyme Commission Number: EC 3.4.21.39. CAS No. 97501-92-3. CMA1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4133; chymase; EC 3.4.21.39; 97501-92-3; mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase, chymase; skeletal muscle (SK) protease. Cat No: EXWM-4133. |  |
| Chymase from Human, Recombinant | Chymases are a family of serine proteases found primarily in mast cells, though also present in basophil granulocytes (e.g. alpha chymase mcpt8). They show broad peptidolytic activity and are involved in a variety of functions. For example, chymases are released by mucosal mast cells upon challenge with parasites and parasite antigens promoting an inflammatory response. Chymases are also known to convert angiotensin I to angiotensin II and thus play a role in hypertension and atherosclerosis. Because of its role in inflammation it has been investigated as a target in the treatment of asthma. Applications: Chymase has been implicated in generation of angiotensin ii and cleavag. Synonyms: mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase, chymase; skeletal muscle (SK) protease; chymase; EC 3.4.21.39; 97501-92-3. Enzyme Commission Number: EC 3.4.21.39. CAS No. 97501-92-3. Purity: >90% (SDS-PAGE). CMA1. Mole weight: ~30 kDa. Activity: >40 units/mg protein. Storage: Store at -20°C. Form: Supplied as a solution in 20 mM Tris, 0.8 M NaCl and 25% glycerol, pH 7.6. Source: Pichia pastoris. Species: Human. mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase, chymase; skeletal muscle (SK) protease; chymase; EC 3.4.21.39; 97501-92-3. Cat No: NATE-0817. | |
| Chymase-IN-1 | Chymase-IN-1 is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase with an IC50 of 29 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 862090-74-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-100269. | |
| chymopapain | The major endopeptidase of papaya (Carica papaya) latex. It has multiple chromatographic forms. In peptidase family C1 (papain family). Group: Enzymes. Synonyms: chymopapain A; chymopapain B; chymopapain S. Enzyme Commission Number: EC 3.4.22.6. CAS No. 9001-9-6. Chymopapain. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4235; chymopapain; EC 3.4.22.6; 9001-09-6; chymopapain A; chymopapain B; chymopapain S. Cat No: EXWM-4235. | |
| chymosin | Neonatal gastric enzyme with high milk clotting and weak general proteolytic activity, formed from prochymosin. Found among mammals with postnatal uptake of immunoglobulins. In peptidase family A1(pepsin A family). Group: Enzymes. Synonyms: rennin (but this should be avoided since it leads to confusion with renin). Enzyme Commission Number: EC 3.4.23.4. CAS No. 9001-98-3. Rennin. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4276; chymosin; EC 3.4.23.4; 9001-98-3; rennin (but this should be avoided since it leads to confusion with renin). Cat No: EXWM-4276. | |
| Chymostatin | Chymostatin is a bioactive peptide that acts as a protease inhibitor with selectivity for chymotryptase-like serine proteases. It potently inhibits chymotrypsin and chymase, but it cannot block the activity of cathepsins, papain, and leukocyte elastase effectively. It doesn't have effect on trypsin, thrombin, plasmin, pepsin, and kallikrein. Uses: Serine proteinase inhibitors. Synonyms: [(S)-1-Carboxy-2-phenylethyl]-carbamoyl-a-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A= Leu B=Val C=Ile]-phenylalaninal (Mixture). Grade: ≥95% (a mixture of A, B, C). CAS No. 9076-44-2. Molecular formula: CxHyN7O6. Mole weight: 607.7. | |
| Chymostatin | Chymostatin is a SARS-CoV-2 Mpro inhibitor. Chymostatin up-regulates endocan and inhibits NF-κBp65 activity. Chymostatin reduces proinflammatory cytokines (IL-1β and IL-6) and HMGB1. Chymostatin shows protective effects against Paraquat-induced acute lung injury. Chymostatin exhibits anticancer activity against lung cancer[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9076-44-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P3042. | |
| Chymostatin A | It is produced by the strain of Streptomyces hygroscopicus and Str.lavendulae. Chymostatin A can be used to inhibit chymotrypsin, papain and other serine/cysteine endopeptidase. Molecular formula: C31H41N7O6. Mole weight: 607.70. | |
| Chymotrypsin | Chymotrypsin (EC 3.4.21.1; Chymotrypsin A) is an orally effective inhibitor targeting molecules such as TLR4, NF-κB, MMP-1, TNF-α, IL-1β, and IL-6. Chymotrypsin downregulates the TLR4/NF-κB signaling pathway, inhibiting the release of inflammatory factors, reducing cell infiltration and tissue damage. It also reduces the expression of tumor cell adhesion molecules (such as CD44 and CD54) and can be specifically detected by fluorescent probes (such as NBD-3). Chymotrypsin has anti-inflammatory, hepatoprotective, joint damage-reducing, liver protection against lipotoxicity, and anti-tumor metastasis functions. It can be used in research on diseases such as rheumatoid arthritis, non-alcoholic fatty liver disease, and melanoma metastasis. Chymotrypsin can be used in studies of inflammation, edema, and expectoration[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EC 3.4.21.1; Chymotrypsin A. CAS No. 9004-7-3. Pack Sizes: 500 mg; 1 g. Product ID: HY-108910. | |
| Chymotrypsin | Chymotrypsin is a proteolytic enzyme. It can priority hydrolyze tyrosine containing l-isomer, phenylalanine and the peptide bond of tryptophan, the best effective condition is pH 8.0. Its activity can be restrained by heavy metal or natural trypsin inhibitor in some degrees. Applications: Practically used to heal cicatrisation caused by injuries, inflammation and it is also used for avoiding part dropsy, blood-gathering, haematoma caused by wrick, breast dropsy after operation, tympanitis and rhinitis brief introduction of production: the high purity chymotrypsin is extracted from bovine or porcine pancreas and purified by affinity chromatography in order to avoid being polluted by other protease. Group: Enzymes. Synonyms: Chymotrypsin; Alpha-chymotrypsin; Chymotrypsin A; Chymotrypsin B. CAS No. 9004-7-3. Chymotrypsin. Appearance: inquire. Chymotrypsin; Alpha-chymotrypsin; Chymotrypsin A; Chymotrypsin B. Pack: inquire. Cat No: BIO-1012. | |
| Chymotrypsin 1000usp-E/m | Chymotrypsin 1000usp-E/m. | CA, FL & NJ |
| chymotrypsin C | Formed from pig chymotrypsinogen C, and from cattle subunit II of procarboxypeptidase A. Reacts more readily with Tos-Leu-CH2Cl than Tos-Phe-CH2Cl in contrast to chymotrypsin. In peptidase family S1 (trypsin family). Group: Enzymes. Enzyme Commission Number: EC 3.4.21.2. CAS No. 9036-9-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4119; chymotrypsin C; EC 3.4.21.2; 9036-09-3. Cat No: EXWM-4119. | |
| Chymotrypsin from Human, Recombinant | Chymotrypsin is a recombinant serine endopeptidase expressed in E.coli, purified with HPLC, the gene sequence is the same as human chymotrypsin. Recombinant chymotrypsin hydrolyzes at the carboxyl side of aromatic amino acids residues: Tyr, Phe and Trp. Cleavage may also be observed, but at a lower rate, at Leu and Met. Chymotrypsin activity is optimal in pH 7.0-9.0. Applications: Hydrolysis of proteins by chymotrypsin alone or in combination with other proteases. suitable for peptide mapping, fingerprinting, and sequence analysis. Group: Enzymes. Synonyms: EC 3.4.21.1; chymotrypsins A and B; alpha-chymar ophth; avazyme; chymar; chymotest; enzeon; quimar; quimotrase; alpha-chymar; alpha-chymotrypsin A; alpha-chymotrypsin; Chymotrypsin; &alpha. Enzyme Commission Number: EC 3.4.21.1. CAS No. 9004-7-3. Purity: > 95% by HPLC. Chymotrypsin. Mole weight: 26,950 Da. Activity: >1000 unit/mg protein. Storage: Recombinant Chymotrypsin lyophilized should be stored under 2°C-8°C in sealed container. It is stable within 24 months. After dissolved, it should be stored under -20°C. Form: White lyophilized. Source: E. coli. Species: Human. EC 3.4.21.1; chymotrypsins A and B; alpha-chymar ophth; avazyme; chymar; chymotest; enzeon; quimar; quimotrase; alpha-chymar; alpha-chymotrypsin A; alpha-chymotrypsin; Chymotrypsin; α-Chymotrypsin. Cat No: NATE-1890. | |
| Chymotrypsin (MS grade) | Chymotrypsin (EC 3.4.21.1; Chymotrypsin A) (MS grade) is an orally effective inhibitor targeting molecules such as TLR4, NF-κB, MMP-1, TNF-α, IL-1β, and IL-6. Chymotrypsin (MS grade) downregulates the TLR4/NF-κB signaling pathway, inhibits the release of inflammatory factors, reduces cell infiltration and tissue damage, and also reduces the expression of tumor cell adhesion molecules (such as CD44 and CD54). It can also be specifically detected by fluorescent probes (such as NBD-3). Chymotrypsin (MS grade) has anti-inflammatory, hepatoprotective, joint damage-reducing, liver protection against lipotoxicity, and anti-tumor metastasis functions, and can be used in the research of diseases such as rheumatoid arthritis, non-alcoholic fatty liver disease, and melanoma metastasis. Chymotrypsin (MS grade) can be used in studies of inflammation, edema, and expectoration[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EC 3.4.21.1 (MS grade); Chymotrypsin A (MS grade). CAS No. 9004-7-3. Pack Sizes: 50 μg. Product ID: HY-108910A. | |
| Chymotrypsin-polyethylene glycol | Enzyme PEG conjugate was made from by the covalent attachment of PEG 5000 to the enzyme molecule via its amino grops. Conjugate is provided in lyophilized powder form. Group: Enzymes. Synonyms: Chymotrypsin PEG Conjugate; Chymotrypsin-PEG; PEG-Chymotrypsin; Chymotrypsin-polyethylene glycol. Chymotrypsin. Storage: Store at -20°C. Form: Lyophilized powder. Chymotrypsin PEG Conjugate; Chymotrypsin-PEG; PEG-Chymotrypsin; Chymotrypsin; PEG; Chymotrypsin-polyethylene glycol. Cat No: NATE-1581. | |
| CHZ868 | CHZ868 is a type II JAK2 inhibitor with an IC50 of 0.17 μM in EPOR JAK2 WT Ba/F3 cell. Uses: Scientific research. Category: Signaling pathways. CAS No. 1895895-38-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-18960. | |
| CHZ868 | CHZ868 is a potent and selective type II JAK2 inhibitor (IC50 = 0.17 μM in EPOR JAK2 WT Ba/F3 cell). CHZ868 potently inhibited proliferation of cells expressing the JAK2V617F mutation or the TEL-JAK2 fusion. Synonyms: Acetamide, N-[4-[[2-[(2,4-difluorophenyl)amino]-1,4-dimethyl-1H-benzimidazol-5-yl]oxy]-2-pyridinyl]-; N-(4-{[2-(2,4-difluoroanilino)-1,4-dimethyl-1H-benzimidazol-5-yl]oxy}pyridin-2-yl)acetamide; N-[4-[2-[[2,4-bis(fluoranyl)phenyl]amino]-1,4-dimethyl-benzimidazol-5-yl]oxypyridin-2-yl]ethanamide. Grade: 98%. CAS No. 1895895-38-1. Molecular formula: C22H19F2N5O2. Mole weight: 423.42. | |
| CI 1002 | CI 1002, an azepinoquinazoline derivative, has been found to be an acetylcholinesterase inhibitor that could probably be effective against cognitive dysfunction in Alzheimer's disease. It has already been discontinued by Pfizer. Synonyms: UNII-7U374ZW3YB; CI-1002; CI 1002; CI1002; 1,3-Dichloro-6,7,8,9,10,12-hexahydroazepino(2,1-b)quinazoline; 1,3-dichloro-6,7,8,9,10,12-hexahydroazepino[2,1-b]quinazoline; PD-142676; PD 142676; PD142676. Grade: 98%. CAS No. 149028-28-4. Molecular formula: C13H14Cl2N2. Mole weight: 269.17. | |
| CI-1002 hydrochloride | The hydrochloride salt form of CI 1002, an azepinoquinazoline derivative, has been found to be an acetylcholinesterase inhibitor that could probably be effective against cognitive dysfunction in Alzheimer's disease. Synonyms: CI-1002 hydrochloride; CI 1002 hydrochloride; CI1002 hydrochloride; UNII-I77CZ53Y9M; PharmaGSID_47259; 149062-75-9; 1,3-Dichloro-6,7,8,9,10,12-hexahydroazepino(2,1-b)quinazoline hydrochloride; CI-1002 hydrochloride; 1,3-dichloro-6,7,8,9,10,12-hexahydroazepino[2,1-b]quinazoline hydrochloride. Grade: 98%. CAS No. 149062-75-9. Molecular formula: C13H15Cl3N2. Mole weight: 305.63. | |
| CI-1018 | CI-1018 is a selective type 4 phosphodiesterase inhibitor associated with vasculitis. CI-1018 has been in development to suppress inflammation. Synonyms: 4-Pyridinecarboxamide, N-(3,4,6,7-tetrahydro-9-methyl-4-oxo-1-phenylpyrrolo(3,2,1-jk)(1,4)benzodiazepin-3-yl)-; CI-1018; CI-1018; CI-1018; UNII-05127JZ9KQ. Grade: >98%. CAS No. 245329-99-1. Molecular formula: C24H20N4O2. Mole weight: 396.44. | |
| CI 1020 | CI 1020 has been found to be a novel endothelin-A receptor antagonist and could be used as an antihypertensive agent. Synonyms: CI 1020; CI1020; CI-1020; 3-(1,3-Benzodioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]-2(5H)-furanone. Grade: ≥98% by HPLC. CAS No. 162256-50-0. Molecular formula: C28H26O9. Mole weight: 506.50. | |
| CI 1020 | CI 1020. Group: Biochemicals. Alternative Names: 3- (1, 3-Benzodioxol-5-yl) -5-hydroxy-5- (4-methoxyphenyl) -4-[ (3, 4, 5-trimethoxyphenyl) methyl]-2 (5H) -furanone; PD 156707. Grades: Highly Purified. CAS No. 162256-50-0. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C28H26O9. US Biological Life Sciences. | Worldwide |
| CI-1029 | CI-1029 is a nonpeptidic inhibitor of HIV protease, potenat against mutant HIV protease and resistant HIV strains. Synonyms: CI-1029; CI 1029; CI1029; UNII-VDH375TRL9; PD178390; PD 178390; PD0178390; (2S)-2-[2-(4-aminophenyl)ethyl]-5-[2-tert-butyl-4-(hydroxymethyl)-5-methylphenyl]sulfanyl-4-hydroxy-2-propan-2-yl-3H-pyran-6-one. Grade: >98%. CAS No. 207736-05-8. Molecular formula: C28H37NO4S. Mole weight: 483.66. | |
| CI-1040 | CI-1040 is a MEK inhibitor, which demonstrated in vivo activity in preclinical animal models and subsequently became the first MEK inhibitor to enter clinical trial. CI-1040 suffered however from poor exposure due to its poor solubility and rapid clearance, and as a result, development of the compound was terminated. Synonyms: CI1040; CI-1040; CI 1040; PD184352; PD 184352; PD-184352. CAS No. 212631-79-3. Molecular formula: C17H14ClF2IN2O2. Mole weight: 478.662. | |
| CI-1040 | CI-1040 (PD 184352) is an orally active, highly specific, small-molecule inhibitor of MEK with an IC50 of 17 nM for MEK1. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PD 184352. CAS No. 212631-79-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 1 g. Product ID: HY-50295. | |
| CI-1044 | CI-1044, a selective PDE4 inhibitor, inhibits in vitro LPS-induced TNF-alpha release in whole blood from COPD patients better than rolipram and cilomilast and suggested that it could be a useful anti-inflammatory therapy in COPD. Synonyms: CI-1044; CI 1044; CI1044; UNII-O4T475XIIY; PD-189659; PD 189659; PD189659; N-(9-amino-4-oxo-1-phenyl-3,4,6,7-tetrahydro(1,4)diazepino(6,7,1-hi)indol-3-yl)nicotinamide. Grade: >98%. CAS No. 197894-84-1. Molecular formula: C23H19N5O2. Mole weight: 397.43. | |
| CI 600 | CI 600 is a bio-active chemical, but no detailed information has been published yet. Synonyms: CI 600; CI600; CI-600; Methylaminopropyldibenzodiazepinone; 5,10-Dihydro-5-(3-(methylamino)propyl)-11H-dibenzo(b,e)(1,4)diazepin-11-one; 5,10-Dihydro-5-[3-(methylamino)propyl]-11H-dibenzo[b,e][1,4]diazepin-11-one; AC1L2DG1; 63915-70-8 (hydrochloride.monohydrate). Grade: 95%. CAS No. 13450-70-9. Molecular formula: C17H20ClN3O. Mole weight: 317.81. | |
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