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| Product | Description | |
|---|---|---|
| Chrysospermin A | It is produced by the strain of Apiocrea chrysosperma Ap101. Chrysospermin A has antibacterial activities against individual gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis), Klebsiella pneumoniae and individual yeasts (Ocher echinoderma, saccharomyces cerevisiae). CAS No. 160824-57-7. Molecular formula: C90H140N22O23. Mole weight: 1898.20. |  |
| Chrysospermin B | It is produced by the strain of Apiocrea chrysosperma Ap101. Chrysospermin B has antibacterial activities against individual gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis), Klebsiella pneumoniae and individual yeasts (Ocher echinoderma, saccharomyces cerevisiae). Molecular formula: C91H142N22O23. Mole weight: 1912.23. | |
| Chrysospermin C | It is produced by the strain of Apiocrea chrysosperma Ap101. Chrysospermin C has antibacterial activities against individual gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis), Klebsiella pneumoniae and individual yeasts (Ocher echinoderma, saccharomyces cerevisiae). Molecular formula: C91H142N22O23. Mole weight: 1912.23. | |
| Chrysospermin D | It is produced by the strain of Apiocrea chrysosperma Ap101. Chrysospermin D has antibacterial activities against individual gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis), Klebsiella pneumoniae and individual yeasts (Ocher echinoderma, saccharomyces cerevisiae). Molecular formula: C91H144N22O23. Mole weight: 1914.24. | |
| Chrysosplenetin | Chrysosplenetin is a flavonoid isolated from the herbs of Laggera pterodonta, which is a metabolic inhibitor of artemisinin. Uses: Anti-enterovirus 71. Synonyms: Chrysosplenetin B; 3,6,7,3'-Tetramethylquercetagetin; 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one; EMD-20940; 4H-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxy-. Grade: 99%. CAS No. 603-56-5. Molecular formula: C19H18O8. Mole weight: 374.4. | |
| Chrysosplenetin | Chrysosplenetin is an orally active polymethoxyflavone. Chrysosplenetin exerts anticancer effects by inhibiting topoisomerase, protecting DNA and inducing apoptosis. Chrysosplenetin acts as an antimalarial sensitizer, reverses Artemisinin (HY-B0094) resistance by inhibiting and downregulating P-glycoprotein, and enhances the efficacy of Artemisinin. Chrysosplenetin promotes bone formation by activating the Wnt/β-catenin pathway and exerts anti-osteoporotic effects[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 603-56-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-N1457. |  |
| Chrysosplenol C | Chrysosplenol C is a trimethoxyflavone that is the 3,7,3'-trimethyl ether derivative of quercetagetin. It has a role as an antineoplastic agent and an antiviral agent. Synonyms: Quercetagetin 3,7,3'-trimethyl ether; 3,7,3'-trimethylquercetagetin. Grade: 98%. CAS No. 23370-16-3. Molecular formula: C18H16O8. Mole weight: 360.32. | |
| CHRYSOSPLENOLD | Chrysosplenol D isolated from the herbs of Artemisia annua L. Uses: Antibiotics and antimalarials. Synonyms: 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,6,7-trimethoxychromen-4-one. Grade: 98.5%. CAS No. 14965-20-9. Molecular formula: C18H16O8. Mole weight: 360.3. | |
| CHS-828 | CHS-828 is a synthetic guanidine-based small anticancer molecule. CHS 828 was found to exert potent cytotoxic effects in human breast and lung cancer cell lines, with lesser effects on normal fibroblasts and endothelial cells. In nude mice bearing human tumor xenografts, CHS 828, at doses from 20 to 50 mg/kg/day p.o., inhibited the growth of MCF-7 breast cancer tumors and caused regression of NYH small cell lung cancer tumors. Oral administration of CHS 828 once weekly improved efficacy without increasing toxicity. CHS 828 was found to compare favorably with established chemotherapeutic agents such as cyclophosphamide, etoposide, methotrexate, and paclitaxel. In mice with NYH tumors, long-term survival (>6 months) was observed after treatment with CHS 828 was stopped. CHS 828 is an effective new antitumor agent, with a potentially new mechanism of action. CHS-828 appeared to kill cancer cells by depleting NAD. CHS 828 is presently being tested in Phase I clinical trials in collaboration with the European Organization for Research and Treatment of Cancer. Synonyms: CHS 828; CHS828; CHS-828; GMX-1778; GMX1778; GMX 1778. CAS No. 200484-11-3. Molecular formula: C19H22ClN5O. Mole weight: 371.869. | |
| CHS-828 | Antitumor compound. Programmed cell death inducer. Cytotoxic. Antiproliferative. p53 activator. IkappaB kinase inhibitor. NF-kappaB inhibitor. Nampt/visfatin inhibitor. Group: Biochemicals. Alternative Names: GMX1778, (E)-1--2-cyano-3-(pyridin-4-yl)guanidine. Grades: Highly Purified. CAS No. 200484-11-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C19H22ClN5O. US Biological Life Sciences. |  Worldwide |
| CHS-828 | CHS-828 (GMX1778) is a competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), with an IC50 less than 25 nM. CHS-828 (GMX1778) exerts a cytotoxic effect by decreasing the cellular level of NAD+ and exhibits a potent anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GMX1778. CAS No. 200484-11-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10079. | |
| Chst15-IN-1 | Chst15-IN-1 is a potent reversible covalent Chst15 inhibitor. Chst15-IN-1 effectively inhibits chondroitin sulfate-E (CS-E) sulfation levels and other closely related glycosaminoglycans (GAG) sulfotransferases. Chst15-IN-1, as a selective sulfotransferase inhibitor, can diminish the inhibitory effects of chondroitin sulfate proteoglycans (CSPGs), and can be used for the stimulation of neuronal repair[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2158198-77-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124704. | |
| Chuangxinmycin | Chuangxinmycin is produced by the strain of Actinoplanes jinanensis. It has activities against Staphylococcus aureus, Haemophilus influenzae, Escherichia coli and Shigella laminae. Synonyms: Chuanghsinmycin; (-)-chuangxinmycin; cis-(-)-3,5-Dihydro-3-methyl-2H-thiopyrano(4,3,2-cd)indole-2-carboxylic acid. CAS No. 63339-68-4. Molecular formula: C12H11NO2S. Mole weight: 233.29. | |
| Chuchuhuasi Bark Powder (Peru) | Chuchuhuasi Bark Powder (Peru). |  CA, FL & NJ |
| CHU N6 VITAMIN SOL. (1000x) | CHU N6 VITAMIN SOL. (1000x). Product ID: ACMA00011419. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| CHU N6 VITAMIN SOLUTION (1000X) | CHU N6 VITAMIN SOLUTION (1000X). Product ID: ACMA00011318. Alfa Chemistry - ISO 9001:32057 Certified. | |
| CHU'S N6 BASAL MED. W/ VITAMIN | CHU'S N6 BASAL MED. W/ VITAMIN. Product ID: ACMA00011418. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Chute Lining | Chute Lining. |  |
| ChX710 | ChX710 efficiently primed cellular response to transfected plasmid DNA as assessed by potent synergistic effects on IFN-β secretion and ISG expression levels. This cellular response was dependent on STING. Synonyms: N-(1-(Dimethylamino)propan-2-yl)-2-(pyridin-4-yl)-1H-benzo[d]imidazole-7-carboxamide. Grade: 98%. CAS No. 2438721-44-7. Molecular formula: C18H21N5O. Mole weight: 323.39. | |
| chymase | In mast cell granules. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase, chymase; skeletal muscle (SK) protease. Enzyme Commission Number: EC 3.4.21.39. CAS No. 97501-92-3. CMA1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4133; chymase; EC 3.4.21.39; 97501-92-3; mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase, chymase; skeletal muscle (SK) protease. Cat No: EXWM-4133. |  |
| Chymase from Human, Recombinant | Chymases are a family of serine proteases found primarily in mast cells, though also present in basophil granulocytes (e.g. alpha chymase mcpt8). They show broad peptidolytic activity and are involved in a variety of functions. For example, chymases are released by mucosal mast cells upon challenge with parasites and parasite antigens promoting an inflammatory response. Chymases are also known to convert angiotensin I to angiotensin II and thus play a role in hypertension and atherosclerosis. Because of its role in inflammation it has been investigated as a target in the treatment of asthma. Applications: Chymase has been implicated in generation of angiotensin ii and cleavag. Synonyms: mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase, chymase; skeletal muscle (SK) protease; chymase; EC 3.4.21.39; 97501-92-3. Enzyme Commission Number: EC 3.4.21.39. CAS No. 97501-92-3. Purity: >90% (SDS-PAGE). CMA1. Mole weight: ~30 kDa. Activity: >40 units/mg protein. Storage: Store at -20°C. Form: Supplied as a solution in 20 mM Tris, 0.8 M NaCl and 25% glycerol, pH 7.6. Source: Pichia pastoris. Species: Human. mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase, chymase; skeletal muscle (SK) protease; chymase; EC 3.4.21.39; 97501-92-3. Cat No: NATE-0817. | |
| Chymase-IN-1 | Chymase-IN-1 is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase with an IC50 of 29 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 862090-74-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-100269. | |
| chymopapain | The major endopeptidase of papaya (Carica papaya) latex. It has multiple chromatographic forms. In peptidase family C1 (papain family). Group: Enzymes. Synonyms: chymopapain A; chymopapain B; chymopapain S. Enzyme Commission Number: EC 3.4.22.6. CAS No. 9001-9-6. Chymopapain. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4235; chymopapain; EC 3.4.22.6; 9001-09-6; chymopapain A; chymopapain B; chymopapain S. Cat No: EXWM-4235. | |
| chymosin | Neonatal gastric enzyme with high milk clotting and weak general proteolytic activity, formed from prochymosin. Found among mammals with postnatal uptake of immunoglobulins. In peptidase family A1(pepsin A family). Group: Enzymes. Synonyms: rennin (but this should be avoided since it leads to confusion with renin). Enzyme Commission Number: EC 3.4.23.4. CAS No. 9001-98-3. Rennin. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4276; chymosin; EC 3.4.23.4; 9001-98-3; rennin (but this should be avoided since it leads to confusion with renin). Cat No: EXWM-4276. | |
| Chymostatin | Chymostatin is a bioactive peptide that acts as a protease inhibitor with selectivity for chymotryptase-like serine proteases. It potently inhibits chymotrypsin and chymase, but it cannot block the activity of cathepsins, papain, and leukocyte elastase effectively. It doesn't have effect on trypsin, thrombin, plasmin, pepsin, and kallikrein. Uses: Serine proteinase inhibitors. Synonyms: [(S)-1-Carboxy-2-phenylethyl]-carbamoyl-a-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A= Leu B=Val C=Ile]-phenylalaninal (Mixture). Grade: ≥95% (a mixture of A, B, C). CAS No. 9076-44-2. Molecular formula: CxHyN7O6. Mole weight: 607.7. | |
| Chymostatin | Chymostatin is a SARS-CoV-2 Mpro inhibitor. Chymostatin up-regulates endocan and inhibits NF-κBp65 activity. Chymostatin reduces proinflammatory cytokines (IL-1β and IL-6) and HMGB1. Chymostatin shows protective effects against Paraquat-induced acute lung injury. Chymostatin exhibits anticancer activity against lung cancer[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9076-44-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P3042. | |
| Chymostatin A | It is produced by the strain of Streptomyces hygroscopicus and Str.lavendulae. Chymostatin A can be used to inhibit chymotrypsin, papain and other serine/cysteine endopeptidase. Molecular formula: C31H41N7O6. Mole weight: 607.70. | |
| Chymotrypsin | Chymotrypsin is a proteolytic enzyme. It can priority hydrolyze tyrosine containing l-isomer, phenylalanine and the peptide bond of tryptophan, the best effective condition is pH 8.0. Its activity can be restrained by heavy metal or natural trypsin inhibitor in some degrees. Applications: Practically used to heal cicatrisation caused by injuries, inflammation and it is also used for avoiding part dropsy, blood-gathering, haematoma caused by wrick, breast dropsy after operation, tympanitis and rhinitis brief introduction of production: the high purity chymotrypsin is extracted from bovine or porcine pancreas and purified by affinity chromatography in order to avoid being polluted by other protease. Group: Enzymes. Synonyms: Chymotrypsin; Alpha-chymotrypsin; Chymotrypsin A; Chymotrypsin B. CAS No. 9004-7-3. Chymotrypsin. Appearance: inquire. Chymotrypsin; Alpha-chymotrypsin; Chymotrypsin A; Chymotrypsin B. Pack: inquire. Cat No: BIO-1012. | |
| Chymotrypsin | Chymotrypsin (EC 3.4.21.1; Chymotrypsin A) is an orally effective inhibitor targeting molecules such as TLR4, NF-κB, MMP-1, TNF-α, IL-1β, and IL-6. Chymotrypsin downregulates the TLR4/NF-κB signaling pathway, inhibiting the release of inflammatory factors, reducing cell infiltration and tissue damage. It also reduces the expression of tumor cell adhesion molecules (such as CD44 and CD54) and can be specifically detected by fluorescent probes (such as NBD-3). Chymotrypsin has anti-inflammatory, hepatoprotective, joint damage-reducing, liver protection against lipotoxicity, and anti-tumor metastasis functions. It can be used in research on diseases such as rheumatoid arthritis, non-alcoholic fatty liver disease, and melanoma metastasis. Chymotrypsin can be used in studies of inflammation, edema, and expectoration[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EC 3.4.21.1; Chymotrypsin A. CAS No. 9004-7-3. Pack Sizes: 500 mg; 1 g. Product ID: HY-108910. | |
| Chymotrypsin 1000usp-E/m | Chymotrypsin 1000usp-E/m. | CA, FL & NJ |
| chymotrypsin C | Formed from pig chymotrypsinogen C, and from cattle subunit II of procarboxypeptidase A. Reacts more readily with Tos-Leu-CH2Cl than Tos-Phe-CH2Cl in contrast to chymotrypsin. In peptidase family S1 (trypsin family). Group: Enzymes. Enzyme Commission Number: EC 3.4.21.2. CAS No. 9036-9-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4119; chymotrypsin C; EC 3.4.21.2; 9036-09-3. Cat No: EXWM-4119. | |
| Chymotrypsin from Human, Recombinant | Chymotrypsin is a recombinant serine endopeptidase expressed in E.coli, purified with HPLC, the gene sequence is the same as human chymotrypsin. Recombinant chymotrypsin hydrolyzes at the carboxyl side of aromatic amino acids residues: Tyr, Phe and Trp. Cleavage may also be observed, but at a lower rate, at Leu and Met. Chymotrypsin activity is optimal in pH 7.0-9.0. Applications: Hydrolysis of proteins by chymotrypsin alone or in combination with other proteases. suitable for peptide mapping, fingerprinting, and sequence analysis. Group: Enzymes. Synonyms: EC 3.4.21.1; chymotrypsins A and B; alpha-chymar ophth; avazyme; chymar; chymotest; enzeon; quimar; quimotrase; alpha-chymar; alpha-chymotrypsin A; alpha-chymotrypsin; Chymotrypsin; &alpha. Enzyme Commission Number: EC 3.4.21.1. CAS No. 9004-7-3. Purity: > 95% by HPLC. Chymotrypsin. Mole weight: 26,950 Da. Activity: >1000 unit/mg protein. Storage: Recombinant Chymotrypsin lyophilized should be stored under 2°C-8°C in sealed container. It is stable within 24 months. After dissolved, it should be stored under -20°C. Form: White lyophilized. Source: E. coli. Species: Human. EC 3.4.21.1; chymotrypsins A and B; alpha-chymar ophth; avazyme; chymar; chymotest; enzeon; quimar; quimotrase; alpha-chymar; alpha-chymotrypsin A; alpha-chymotrypsin; Chymotrypsin; α-Chymotrypsin. Cat No: NATE-1890. | |
| Chymotrypsin (MS grade) | Chymotrypsin (EC 3.4.21.1; Chymotrypsin A) (MS grade) is an orally effective inhibitor targeting molecules such as TLR4, NF-κB, MMP-1, TNF-α, IL-1β, and IL-6. Chymotrypsin (MS grade) downregulates the TLR4/NF-κB signaling pathway, inhibits the release of inflammatory factors, reduces cell infiltration and tissue damage, and also reduces the expression of tumor cell adhesion molecules (such as CD44 and CD54). It can also be specifically detected by fluorescent probes (such as NBD-3). Chymotrypsin (MS grade) has anti-inflammatory, hepatoprotective, joint damage-reducing, liver protection against lipotoxicity, and anti-tumor metastasis functions, and can be used in the research of diseases such as rheumatoid arthritis, non-alcoholic fatty liver disease, and melanoma metastasis. Chymotrypsin (MS grade) can be used in studies of inflammation, edema, and expectoration[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EC 3.4.21.1 (MS grade); Chymotrypsin A (MS grade). CAS No. 9004-7-3. Pack Sizes: 50 μg. Product ID: HY-108910A. | |
| Chymotrypsin-polyethylene glycol | Enzyme PEG conjugate was made from by the covalent attachment of PEG 5000 to the enzyme molecule via its amino grops. Conjugate is provided in lyophilized powder form. Group: Enzymes. Synonyms: Chymotrypsin PEG Conjugate; Chymotrypsin-PEG; PEG-Chymotrypsin; Chymotrypsin-polyethylene glycol. Chymotrypsin. Storage: Store at -20°C. Form: Lyophilized powder. Chymotrypsin PEG Conjugate; Chymotrypsin-PEG; PEG-Chymotrypsin; Chymotrypsin; PEG; Chymotrypsin-polyethylene glycol. Cat No: NATE-1581. | |
| CHZ868 | CHZ868 is a type II JAK2 inhibitor with an IC50 of 0.17 μM in EPOR JAK2 WT Ba/F3 cell. Uses: Scientific research. Category: Signaling pathways. CAS No. 1895895-38-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-18960. | |
| CHZ868 | CHZ868 is a potent and selective type II JAK2 inhibitor (IC50 = 0.17 μM in EPOR JAK2 WT Ba/F3 cell). CHZ868 potently inhibited proliferation of cells expressing the JAK2V617F mutation or the TEL-JAK2 fusion. Synonyms: Acetamide, N-[4-[[2-[(2,4-difluorophenyl)amino]-1,4-dimethyl-1H-benzimidazol-5-yl]oxy]-2-pyridinyl]-; N-(4-{[2-(2,4-difluoroanilino)-1,4-dimethyl-1H-benzimidazol-5-yl]oxy}pyridin-2-yl)acetamide; N-[4-[2-[[2,4-bis(fluoranyl)phenyl]amino]-1,4-dimethyl-benzimidazol-5-yl]oxypyridin-2-yl]ethanamide. Grade: 98%. CAS No. 1895895-38-1. Molecular formula: C22H19F2N5O2. Mole weight: 423.42. | |
| CI 1002 | CI 1002, an azepinoquinazoline derivative, has been found to be an acetylcholinesterase inhibitor that could probably be effective against cognitive dysfunction in Alzheimer's disease. It has already been discontinued by Pfizer. Synonyms: UNII-7U374ZW3YB; CI-1002; CI 1002; CI1002; 1,3-Dichloro-6,7,8,9,10,12-hexahydroazepino(2,1-b)quinazoline; 1,3-dichloro-6,7,8,9,10,12-hexahydroazepino[2,1-b]quinazoline; PD-142676; PD 142676; PD142676. Grade: 98%. CAS No. 149028-28-4. Molecular formula: C13H14Cl2N2. Mole weight: 269.17. | |
| CI-1002 hydrochloride | The hydrochloride salt form of CI 1002, an azepinoquinazoline derivative, has been found to be an acetylcholinesterase inhibitor that could probably be effective against cognitive dysfunction in Alzheimer's disease. Synonyms: CI-1002 hydrochloride; CI 1002 hydrochloride; CI1002 hydrochloride; UNII-I77CZ53Y9M; PharmaGSID_47259; 149062-75-9; 1,3-Dichloro-6,7,8,9,10,12-hexahydroazepino(2,1-b)quinazoline hydrochloride; CI-1002 hydrochloride; 1,3-dichloro-6,7,8,9,10,12-hexahydroazepino[2,1-b]quinazoline hydrochloride. Grade: 98%. CAS No. 149062-75-9. Molecular formula: C13H15Cl3N2. Mole weight: 305.63. | |
| CI-1018 | CI-1018 is a selective type 4 phosphodiesterase inhibitor associated with vasculitis. CI-1018 has been in development to suppress inflammation. Synonyms: 4-Pyridinecarboxamide, N-(3,4,6,7-tetrahydro-9-methyl-4-oxo-1-phenylpyrrolo(3,2,1-jk)(1,4)benzodiazepin-3-yl)-; CI-1018; CI-1018; CI-1018; UNII-05127JZ9KQ. Grade: >98%. CAS No. 245329-99-1. Molecular formula: C24H20N4O2. Mole weight: 396.44. | |
| CI 1020 | CI 1020 has been found to be a novel endothelin-A receptor antagonist and could be used as an antihypertensive agent. Synonyms: CI 1020; CI1020; CI-1020; 3-(1,3-Benzodioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]-2(5H)-furanone. Grade: ≥98% by HPLC. CAS No. 162256-50-0. Molecular formula: C28H26O9. Mole weight: 506.50. | |
| CI 1020 | CI 1020. Group: Biochemicals. Alternative Names: 3- (1, 3-Benzodioxol-5-yl) -5-hydroxy-5- (4-methoxyphenyl) -4-[ (3, 4, 5-trimethoxyphenyl) methyl]-2 (5H) -furanone; PD 156707. Grades: Highly Purified. CAS No. 162256-50-0. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C28H26O9. US Biological Life Sciences. | Worldwide |
| CI-1029 | CI-1029 is a nonpeptidic inhibitor of HIV protease, potenat against mutant HIV protease and resistant HIV strains. Synonyms: CI-1029; CI 1029; CI1029; UNII-VDH375TRL9; PD178390; PD 178390; PD0178390; (2S)-2-[2-(4-aminophenyl)ethyl]-5-[2-tert-butyl-4-(hydroxymethyl)-5-methylphenyl]sulfanyl-4-hydroxy-2-propan-2-yl-3H-pyran-6-one. Grade: >98%. CAS No. 207736-05-8. Molecular formula: C28H37NO4S. Mole weight: 483.66. | |
| CI-1040 | CI-1040 is a MEK inhibitor, which demonstrated in vivo activity in preclinical animal models and subsequently became the first MEK inhibitor to enter clinical trial. CI-1040 suffered however from poor exposure due to its poor solubility and rapid clearance, and as a result, development of the compound was terminated. Synonyms: CI1040; CI-1040; CI 1040; PD184352; PD 184352; PD-184352. CAS No. 212631-79-3. Molecular formula: C17H14ClF2IN2O2. Mole weight: 478.662. | |
| CI-1040 | CI-1040 (PD 184352) is an orally active, highly specific, small-molecule inhibitor of MEK with an IC50 of 17 nM for MEK1. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PD 184352. CAS No. 212631-79-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 1 g. Product ID: HY-50295. | |
| CI-1044 | CI-1044, a selective PDE4 inhibitor, inhibits in vitro LPS-induced TNF-alpha release in whole blood from COPD patients better than rolipram and cilomilast and suggested that it could be a useful anti-inflammatory therapy in COPD. Synonyms: CI-1044; CI 1044; CI1044; UNII-O4T475XIIY; PD-189659; PD 189659; PD189659; N-(9-amino-4-oxo-1-phenyl-3,4,6,7-tetrahydro(1,4)diazepino(6,7,1-hi)indol-3-yl)nicotinamide. Grade: >98%. CAS No. 197894-84-1. Molecular formula: C23H19N5O2. Mole weight: 397.43. | |
| CI 600 | CI 600 is a bio-active chemical, but no detailed information has been published yet. Synonyms: CI 600; CI600; CI-600; Methylaminopropyldibenzodiazepinone; 5,10-Dihydro-5-(3-(methylamino)propyl)-11H-dibenzo(b,e)(1,4)diazepin-11-one; 5,10-Dihydro-5-[3-(methylamino)propyl]-11H-dibenzo[b,e][1,4]diazepin-11-one; AC1L2DG1; 63915-70-8 (hydrochloride.monohydrate). Grade: 95%. CAS No. 13450-70-9. Molecular formula: C17H20ClN3O. Mole weight: 317.81. | |
| CI 750 | CI-750 is a novel antidiarrheal agent. Uses: Antidiarrheal. Synonyms: CI 750; CI750; CI750. 1-(((2-Chloro-3-methoxyphenyl)methyl)methylamino)-N,N-diethyl-2,3-dihydro-3-phenyl-1H-indole-3-ethanamine. Grade: ≥98%. CAS No. 47739-68-4. Molecular formula: C29H36ClN3O. Mole weight: 478.07. | |
| CI-898 hydrochloride | CI-898 is a lipophilic antifolate inhibitor of dihydrofolate reductase (DHFR). The presence of the cofactor NADPH enhances bind of CI-898 and DHFR. CI-898 inhibits growth and halts the cell cycle at the G1/S phase in L1210 mouse lymphocytic leukemia cells and is active against methotrexate-resistant cancer cell lines. It also inhibits the growth of S. faecalis and S. aureus when used at concentrations less than 0.25 μg/ml. It also enhances the activity of doxorubicin, cyclophosphamide, and 6-thioguanine in mice with advanced stage P338 leukemia. Synonyms: Trimetrexate; CI 898 trihydrochloride; Trimetrexate trihydrochloride; TMTX. Grade: ≥98%. CAS No. 1658520-97-8. Molecular formula: C19H23N5O3·3HCl. Mole weight: 478.80. | |
| CI 898 trihydrochloride | CI 898 trihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 82952-64-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CI 924 | CI 924 is hypolipidemic agent. It can elevate anti-atherogenic HDL and lower VLDL. Uses: Hypolipidemic agent. Synonyms: CI 924; CI924; CI-924; EINECS 279-174-7. 5,5'-((1,1'-Biphenyl)-2,5-diylbis(oxy))bis(2,2-dimethylpentanoic acid). Grade: 98%. CAS No. 79520-77-7. Molecular formula: C26H34O6. Mole weight: 442.54. | |
| CI-949 | CI-949 is an allergic mediator release inhibitor. It inhibits histamine, leukotriene C4/D4 (LTC4/LTD4), and thromboxane B2 (TXB2) release with IC50s of 11.4 μM, 0.5 μM and 0.1 μM, respectively. Synonyms: 5-methoxy-3-(1-methylethoxy)-1-phenyl-N-1H-tetrazol-5-yl-1H-indole-2-carboxamide. CAS No. 104961-19-5. Molecular formula: C20H20N6O3. Mole weight: 392.41. | |
| CI 951 | CI 951 is a dihydronaphthyridine Ca2+ channel antagonist and it may be applicated for the treatment of focal cerebral ischemia. CI 951 has potential as a cerebral vasodilator. Uses: Focal cerebral ischemia. Synonyms: CI 951; CI-951; CI951. 1,6-Naphthyridine-3-carboxylic acid, 1,4-dihydro-2-methyl-5-(1-methylethoxy)-4-(2-(trifluoromethyl)phenyl)-, ethyl ester. Grade: 98%. CAS No. 126661-07-2. Molecular formula: C22H23F3N2O3. Mole weight: 420.42. | |
| CI-959 free acid | CI-959 free acid is an orally effective inhibitor of cellular activation in both in vitro and animal models. It has antiallergic and anti-inflammatory properties. Uses: Ci-959 free acid has antiallergic and anti-inflammatory properties. Synonyms: CI-959 free acid; CI 959 free acid; CI959 free acid; UNII-Y8M8A93SU8. 3-(1-Methylethoxy)-5-methoxy-N-(1H-tetrazol-5-yl)benzo[b]thiophene-2-carboxamide; 5-Methoxy-3-isopropoxy-N-(1H-tetrazole-5-yl)benzo[b]thiophene-2-carboxamide; Benzo[b]thiophene-2-carboxamide,5-methoxy-3-(1-methylethoxy)-N-2H-tetrazol-5-yl-. Grade: >98 %. CAS No. 104795-66-6. Molecular formula: C14H15N5O3S. Mole weight: 333.37. | |
| CI966 | CI966 is a highly potent and selective blocker of the GABA transporter 1 (GAT-1) with IC50 value of 0.26 μM acting as a central nervous system depressant. It has potential as a potential anxiolytic, anticonvulsant and neuroprotective therapeutic but was discontinued during clinical development due to the incidence of severe adverse effects at higher doses and hence was never marketed. In a phase I human clinical trial it was developed for the treatment of epilepsy. Uses: Ci966 it has potential as a potential anxiolytic, anticonvulsant and neuroprotective therapeutic. it was developed for the treatment of epilepsy. Synonyms: CI-966; CI 966; CI966; CHEMBL77287; CHEMBL542207; 1-(2-(Bis(4-(trifluoromethyl)phenyl)methox)ethyl)-1,2,5,6-tetrahydro-3-pyrdinecarboxylic acid. Grade: >98%. CAS No. 110283-79-9. Molecular formula: C23H21F6NO3. Mole weight: 473.41. | |
| Ci 966 hydrochloride | Ci 966 hydrochloride. CAS No. 110283-66-4. Purity: >98 %. Product ID: ACM110283664. Molecular formula: C23H21F6NO3.HCl. Mole weight: 509.87. Alfa Chemistry - ISO 9001:32057 Certified. | |
| CI 966 hydrochloride | CI 966 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 110283-66-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CI 966 hydrochloride | The hydrochloride salt form of CI 966, which is an inhibitor of the GABA transporter and could be used as anticonvulsive as well as neuroprotective agent. Synonyms: CI 966 hydrochloride; CI966 hydrochloride; CI-966 hydrochloride; 1-[2-[bis[4-(Trifluoromethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydropyridine-3-carboxylic acid hydrochloride. Grade: ≥98% by HPLC. CAS No. 110283-66-4. Molecular formula: C23H21F6NO3.HCl. Mole weight: 509.87. | |
| CI-966 hydrochloride | CI-966 hydrochloride is a potent, selective, orally active and brain-penetrant inhibitor of the GABA transporter GAT-1, with IC50s of 0.26 μM and 1.2 μM for hGAT-1, rGAT-1, respectively. CI-966 hydrochloride shows more than 200-fold selectivity over GAT-2, GAT-3, and BGT-3. CI-966 hydrochloride exhibits anticonvulsant and neuroprotective activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 110283-66-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103534. | |
| CI 969 | This active molecular is a muscarinic agonist agent. Synonyms: CI 969; CI969; CI-969; (Z)-1-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)ethanone O-acetyl oxime hydrochloride. Grade: 98%. CAS No. 113590-49-1. Molecular formula: C10H17ClN2O2. Mole weight: 232.71. | |
| CI 972 | This active molecular is a potent purine nucleoside phosphorylase inhibitor and a T cell-selective immunosuppressive agent. CI-972 inhibited proliferation of human MOLT-4 (T cell) and not MGL-8 (B cell) lymphoblasts with respective IC50s of 3.0 and greater than 50 microM when tested with 10 microM 2'-deoxyguanosine. In Apr 1996, Immunological Disorders section added to drug profile and Immunological disorders in USA was discontinued. Uses: Immunological disorders; transplant rejection. Synonyms: CI 972; CI972; CI-972. 4H-Pyrrolo(3,2-d)pyrimidin-4-one, 2,6-diamino-1,5-dihydro-7-(3-thienylmethyl)-, monohydrochloride. Grade: 98%. CAS No. 115787-68-3. Molecular formula: C11H12ClN5OS. Mole weight: 297.76. | |
| CI 976 | CI 976 has been found to be a selective inhibitor of Acyl-coenzyme A and could probably lower non-high density lipoprotein (HDL)-cholesterol. Uses: Enzyme inhibitors. Synonyms: CI 976; CI-976; CI976; 2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide. Grade: ≥98% by HPLC. CAS No. 114289-47-3. Molecular formula: C23H39NO4. Mole weight: 393.57. | |
| CI 976 | CI 976. Group: Biochemicals. Grades: Purified. CAS No. 114289-47-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CI 986 | CI 986 is a nonulcerogenic anti-inflammatory agent as a Arachidonic acid inhibitor originated by Pfizer. In 1994, Preclinical for Inflammation was discontinued. Uses: Inflammation. Synonyms: CI 986; CI-986; CI986. 2-hydroxy-N,N,N-trimethylethanaminium 2,6-di-tert-butyl-4-(5-thioxo-4,5-dihydro-1,3,4-thiadiazol-2-yl)phenolate. Grade: 98%. CAS No. 130116-16-4. Molecular formula: C21H35N3O2S2. Mole weight: 425.66. | |
| CI 988 | CI 988 has been found to be a CCK-2 receptor antagonist and could exhibit anxiolytic activity. Uses: Anti-anxiety agents. Synonyms: CI 988; CI988; CI-988; PD 134308, PD-134,308, PD-134308; 4-[[(1R)-2-[[(2R)-3-(1H-indol-3-yl)-2-methyl-1-oxo-2-[[(tricyclo[3.3.1.13,7]dec-2-yloxy)carbonyl]amino]propyl]amino]-1-phenylethyl]amino]-4-oxobutanoic acid. Grade: ≥99% by HPLC. CAS No. 130332-27-3. Molecular formula: C35H42N4O6. Mole weight: 614.73. | |
| CI 988 | CI 988. Group: Biochemicals. Grades: Purified. CAS No. 130332-27-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CI-988 | CI-988. Group: Biochemicals. Alternative Names: 4- [ [ (1R) -2- [ [ (2R) -3- (1H-Indol-3-yl) -2-methyl-1-oxo-2- [ [ (tricyclo [3. 3. 1. 13, 7] dec-2-yloxy) carbonyl] amino] propyl] amino] -1-phenylethyl] amino] -4-oxobutanoic acid; CI 988; [R- (R*, R*) ] -4- [ [2- [ [3- (1H-Indol-3-yl) -2-methyl-1-oxo-2- [ [ (tricyclo [3. 3. 1. 13, 7] dec-2-yloxy) carbonyl] amino] propyl] amino] -1-phenylethyl] amino] -4-oxobutanoic acid. Grades: Highly Purified. CAS No. 130332-27-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C35H42N4O6. US Biological Life Sciences. | Worldwide |
| CI 992 | CI 992 is a renin inhibitor originated by Pfizer. Preclinical trials for Hypertension in USA was discontinued in 1994. Uses: Hypertension. Synonyms: CI 992; CI992; CI-992. N-(4-morpholinylsulfonyl)-L-phenylalanyl-3-(2-amino-4-thiazolyl)-N-[(1S,2R,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-alaninamide; [1S-(1R*,2S*,3R*)]- N-(4-morpholinylsulfonyl)-L-phenylalanyl-3-(2-amino-4-thiazolyl)-N-[1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-alaninamide; PD 134672; PD134672; PD-134672. Grade: 98%. CAS No. 135704-06-2. Molecular formula: C33H52N6O7S2. Mole weight: 708.94. | |
| CI 994 | CI 994. Group: Biochemicals. Grades: Purified. CAS No. 112522-64-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CIAC001 | CIAC001 is a novel inhibitor of Pyruvate Kinase with anti-neuroinflammatory activity. CIAC001 inhibits LPS-induced proinflammatory nitric oxide (NO) production and protects immunologically active BV-2 cells (IC50=2.5 μM). Synonyms: (1'R,2'R)-4-(1-(2H-1,2,3-Triazol-2-yl)ethyl)-5'-methyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydro-[1,1'-biphenyl]-2,6-diol. CAS No. 2649154-82-3. Molecular formula: C20H25N3O2. Mole weight: 339.43. | |
| C.I. Acid Black 169(8CI,9CI) | C.I. Acid Black 169(8CI,9CI). CAS No. 12238-88-9. Product ID: ACM12238889. Alfa Chemistry - ISO 9001:32057 Certified. | |
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