A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Dansyl-(D)phenylalanine. Uses: Used for the preparation of n-sulfonylamino acid derivatives as metalloproteinase inhibitors. Alternative Names: N-[[5-(Dimethylamino)-1-naphthalenyl]sulfonyl]-D-phenylalanine; D-Dansylphenylalanine; Dansyl-(R)-phenylalanine; Dansyl-D-Phe; Dansyl-D-phenylalanine; N-Dansyl-D-phenylalanine. Grades: 95%. CAS No. 56176-31-9. Molecular formula: C21H22N2O4S. Mole weight: 398.481.
DANSYL Fluoride is a fluorescent serine probe that acts as an inhibitor of serine-type proteases. Alternative Names: DNSF. CAS No. 34523-28-9. Molecular formula: C12H12FNO2S. Mole weight: 253.30.
Dansyl-Glu-Gly-Arg-chloromethylketone
Dansyl-Glu-Gly-Arg-chloromethylketone, an irreversible inhibitor of plasminogen activator, Factor Xa and urokinase, allows direct monitoring of labeled enzyme interactions. Uses: Fluorescent dyes. Alternative Names: dansylglutamyl-glycyl-arginine chloromethyl ketone; Dns-EGR-CMK; 1,5-Dansyl-L-glutamylglycyl-L-arginine chloromethyl ketone; Dns-Glu-Gly-Arg chloromethyl ketone; Glycinamide, N-((5-(dimethylamino)-1-naphthalenyl)sulfonyl)-L-alpha-glutamyl-N-(4-((aminoiminomethyl)amino)-1-(chloroacetyl)butyl)-, (S)-. Grades: ≥95%. CAS No. 69024-84-6. Molecular formula: C26H36ClN7O7S. Mole weight: 626.13.
Dansyl glutathione
Dansyl glutathione. Alternative Names: N-α-{[5-(dimethylamino)-1-naphthalenyl]sulfonyl}-L-γ-glutamyl-L-cysteinylglycine; Dansyl-GSH; Dns-Glu(Cys-Gly-OH)-OH. CAS No. 75017-02-6. Molecular formula: C32H43N7O14S3. Mole weight: 540.62.
Dansyl glutathione
Dansyl glutathione is a trapping agent for the quantitative estimation and identification of reactive metabolites. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DNS-glutathione. CAS No. 75017-02-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101131.
Dansyl-Gly-Cys-Val-Leu-Ser-OH
Dansyl-Gly-Cys-Val-Leu-Ser-OH is a fluorogenic substrate for farnesyl diphosphate farnesyltransferase (FTase). Alternative Names: Dansyl-GCVLS; N-dansyl-glycyl-L-cysteinyl-L-valyl-L-leucyl-L-serine; N-{[5-(Dimethylamino)-1-naphthyl]sulfonyl}glycyl-L-cysteinyl-L-valyl-L-leucylserine; L-Serine, N-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]glycyl-L-cysteinyl-L-valyl-L-leucyl-. Grades: ≥95% by HPLC. CAS No. 143744-88-1. Molecular formula: C31H46N6O9S2. Mole weight: 710.86.
Dansyl-NECA. Group: Biochemicals. Grades: Purified. CAS No. 219982-12-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Dansyl sarcosine piperidinium salt
Dansyl sarcosine piperidinium salt, a chemical compound utilized in biochemical research, holds a pivotal position in the study of NMDA receptors. Owing to its proficiency in fluorescence detection of glutamate or glycine binding sites on these receptors, it may have the potential to augment the therapeutic treatment of prevalent neurological disorders such as Alzheimer's and Parkinson's. Its multifaceted uses offer researchers the versatility to investigate a host of biological phenomena related to the aforementioned conditions. Alternative Names: Dansylsarcosine piperidinium salt; Piperidin-1-ium 2-(5-(dimethylamino)-N-methylnaphthalene-1-sulfonamido)acetate. Grades: ≥95%. CAS No. 72517-44-3. Molecular formula: C20H29N3O4S. Mole weight: 407.53.
Dansyltryptamine
Dansyltryptamine. CAS No. 13285-17-1. Product ID: ACM13285171. Molecular formula: C22H23N3O2S. Mole weight: 393.5. Alfa Chemistry - ISO 9001:32057 Certified.
Dansyl-Tyr-Val-Gly
Dansyl-Tyr-Val-Gly is a substrate of peptidylglycine monooxygenase (PHM), with a KD of 22 μM for PHM. Dansyl-Tyr-Val-Gly can be used to investigate the catalytic mechanism, kinetics and inactivation characteristics of PHM[1][2]. Uses: Scientific research. Category: Peptides. CAS No. 113527-49-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-138126.
Danthron
1,8-Dihydroxyanthraquinone, an anthraquinone derivative, could be widely used as antioxidant, dye intermediate and a raw material to synthesise sorts of products. Uses: 1,8-dihydroxyanthraquinone could be widely used as antioxidant, dye intermediate and a raw material to synthesise sorts of products. Alternative Names: danthron;1,8-Dihydroxyanthraquinone;117-10-2;Chrysazin;Dantron;Dorbane;Istizin;Antrapurol;Laxanthreen;Diaquone;Laxanorm;Altan;1,8-Dihydroxyanthracene-9,10-dione;Laxipurin;Zwitsalax;Danivac;Dionone;Duolax;Laxipur;9,10-Anthracenedione, 1,8-dihydroxy-;danthrone;Prugol;Roydan;1,8-Dihydroxy-9,10-anthraquinone;1,8-Dihydroxyanthrachinon;Usaf nd-59;Dioxyanthrachinonum;Chrysazine;Dantrone;Dorbanex;1,8-Dihy. Grades: ≥95%. CAS No. 117-10-2. Molecular formula: C14H8O4. Mole weight: 240.21.
Dantocol DHE
100g Pack Size. Group: Building Blocks, Organics. Formula: C9H16N2O4. CAS No. 26850-24-8. Prepack ID 90023172-100g. Molecular Weight 216. See USA prepack pricing.
Dantrolene
Dantrolene is an orally active, non-competitive glutathione reductase inhibitor with a Ki of 111.6 μM and an IC50 of 52.3 μM. Dantrolene is also a calcium channel protein inhibitor. Dantrolene inhibits the release of Ca2+ from RyR1 and RyR3, which can be beneficial in a variety of pathologies caused by disruptions in calcium homeostasis (e.g., stroke, ischemia/reperfusion injury, and neurodegenerative diseases). Dantrolene offers relief of muscle spasms, malignant hyperthermia, and antitoxic, antipyretic, and anti-inflammatory properties[1][2][3][4][5][6][7][8][9][10][11]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: F 368. CAS No. 7261-97-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-12542.
Dantrolene-13C3
A labeled muscle relaxant (skeletal). Used in the treatment of malignant hyperthermia. Group: Biochemicals. Alternative Names: 1- [ [ [5- (4-Nitrophenyl) -2-furanyl] methylene] amino] -2, 4-imidazolidinedione-13C3; Dantrium-13C3. Grades: Highly Purified. CAS No. 1185234-99-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Dantrolene Impurity 1
Dantrolene Impurity 1. Uses: For analytical and research use. Alternative Names: ethyl 2-(1-carbamoyl-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazinyl)acetate. CAS No. 55227-60-6. Molecular formula: C16H16N4O6. Mole weight: 360.11. Catalog: APB55227606.
Dantrolene Impurity 2
5-(4-Nitrophenyl)-2-furaldehyde-(2-carboxymethyl) Semicarbazone is an impurity in the synthesis of Dantrolene, a muscle relaxant (skeletal). Dantrolene is used in the treatment of malignant hyperthermia. Alternative Names: 5-(4-Nitrophenyl)-2-furaldehyde-(2-carboxymethyl) Semicarbazone; [(Aminocarbonyl)[[5-(4-nitrophenyl)-2-furanyl]methylene]hydrazino]acetic Acid; Dantrolene Impurity. Grades: > 95%. CAS No. 57268-33-4. Molecular formula: C14H12N4O6. Mole weight: 332.27.
Dantrolene Impurity 2
Dantrolene Impurity 2. Uses: For analytical and research use. Alternative Names: 2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazinecarboxamide. CAS No. 58136-76-8. Molecular formula: C12H10N4O4. Mole weight: 274.07. Catalog: APB58136768.
Dantrolene Related Compound A
Dantrolene Related Compound A. Uses: For analytical and research use. CAS No. 301359-05-7. Mole weight: 430.37. Catalog: AP301359057.
Dantrolene Related Compound B
Dantrolene Related Compound B. Uses: For analytical and research use. CAS No. 57268-33-4. Mole weight: 332.27. Catalog: AP57268334.
Dantrolene Related Compound C
Dantrolene Related Compound C. Uses: For analytical and research use. CAS No. 7147-77-5. Mole weight: 217.18. Catalog: AP7147775.
Dantrolene sodium
Dantrolene sodium is an orally active, non-competitive glutathione reductase inhibitor with a Ki of 111.6 μM and an IC50 of 52.3 μM. Dantrolene sodium is also a calcium channel protein inhibitor. Dantrolene sodium inhibits the release of Ca2+ from RyR1 and RyR3, which can be beneficial in a variety of pathologies caused by disruptions in calcium homeostasis (e.g., stroke, ischemia/reperfusion injury, and neurodegenerative diseases). Dantrolene sodium offers relief of muscle spasms, malignant hyperthermia, and antitoxic, antipyretic, and anti-inflammatory properties[1][2][3][4][5][6][7][8][9][10][11]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: F 440. CAS No. 14663-23-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-14657.
Dantrolene Sodium
Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It suppresses the release of calcium previously sequestered by skeletal, but not cardiac, muscle sarcoplasmic reticulum. Alternative Names: Dantrolene sodium salt; Dantrium; Sodium 3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-2-oxo-4H-imidazol-5-olate. Grades: 98.0%~102.0%. CAS No. 14663-23-1. Molecular formula: C14H9N4NaO5. Mole weight: 336.239.
Dantrolene sodium hemiheptahydrate
Dantrolene sodium hemiheptahydrate is an orally active, non-competitive glutathione reductase inhibitor with a Ki of 111.6 μM and an IC50 of 52.3 μM. Dantrolene sodium hemiheptahydrate is also a calcium channel protein inhibitor. Dantrolene sodium hemiheptahydrate inhibits the release of Ca2+ from RyR1 and RyR3, which can be beneficial in a variety of pathologies caused by disruptions in calcium homeostasis (e.g., stroke, ischemia/reperfusion injury, and neurodegenerative diseases). Dantrolene sodium hemiheptahydrate offers relief of muscle spasms, malignant hyperthermia, and antitoxic, antipyretic, and anti-inflammatory properties[1][2][3][4][5][6][7][8][9][10][11]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dantrolene sodium hydrate. CAS No. 24868-20-0. Pack Sizes: 100 mg; 500 mg. Product ID: HY-12542A.
Dantrolene Sodium Salt, Anhydrous
Dantrolene sodium is a skeletal muscle relaxant, which inhibits intracellular Ca 2+release from the sarcoplasmic reticulum. Group: Biochemicals. Alternative Names: 1- [ [ [5- (4-Nitrophenyl) -2-furanyl] methylene] amino] -2, 4-imidazolinedione Sodium Salt; Dantrium; Dantrium; F 440; Sodium Dantrolene. Grades: Highly Purified. CAS No. 14663-23-1. Pack Sizes: 5g, 10g, 25g. Molecular Formula: C??H?N?NaO?, Molecular Weight: 336.23. US Biological Life Sciences.
Worldwide
Dantrolene sodium salt hemiheptahydrate
Dantrolene sodium salt hemiheptahydrate. Group: Biochemicals. Alternative Names: 1- [ [ [5- (4-Nitrophenyl) -2-furanyl] methylene] amino] -2, 4-imidazolidinedione sodium salt hemiheptahydrate; Dantrium; Dantrolene sodium hemiheptahydrate. Grades: Highly Purified. CAS No. 24868-20-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C14H9N4NaO5·3.5H2O. US Biological Life Sciences.
A muscle relazant (sketal). Used in the treatment of malignant hyperthermia. Group: Biochemicals. Alternative Names: Dantrium, 1- [ [ [5- (4-Nitrophenyl) -2-furanyl] methylene] amino] -2, 4-imidazolidinedione. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Danuglipron
Danuglipron is an orally small-molecule glucagon-like peptide 1 receptor (GLP-1R) agonist. Danuglipron is undergoing clinical trials for the treatment of diabetes. Alternative Names: PF-06882961; PF 06882961; PF06882961. Grades: 98% by HPLC. CAS No. 2230198-02-2. Molecular formula: C31H30FN5O4. Mole weight: 555.6.
Danuglipron
Danuglipron (PF-06882961) is an orally active glucagon-like peptide-1 receptor (GLP-1R) agonist. Danuglipron has the potential for type 2 diabetes research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-06882961. CAS No. 2230198-02-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125824.
Danuglipron tromethamine
PF-06882961 is a potent, orally bioavailable agonist of the glucagon-like peptide-1 receptor agonist (GLP-1R). Alternative Names: PF-06882961 tromethamine; PF-06882961 Tris; Danuglipron Tris; 2-((4-(6-(4-cyano-2-fluorobenzyloxy)pyridin-2-yl)piperidin-1-yl)methyl)-1-((2S)-oxetan-2-ylmethyl)-1H-benzimidazole-6-carboxylic acid, (1:1) salt with 2-amino-2-(hydroxymethyl)propane-1,3-diol. CAS No. 2230198-03-3. Molecular formula: C35H41FN6O7. Mole weight: 676.75.
Danusertib
Danusertib is a pyrrolo-pyrazole and aurora kinase inhibitor with IC50 of 13, 79, and 61 nM for Aurora A, B, and C, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PHA-739358. CAS No. 827318-97-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10179.
Danusertib
An Aurora kinase inhibitor, used to treat patients with chromic myeloid leukemia. Group: Biochemicals. Alternative Names: 4- (4-Methyl-1-piperazinyl) -N- [1, 4, 5, 6-tetrahydro-5- [ (2R) -2-methoxy-2-phenylacetyl]pyrrolo [3, 4-c]pyrazol-3-yl]benzamide; PHA 739358. Grades: Highly Purified. CAS No. 827318-97-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Danvatirsen
Danvatirsen (AZD9150) is an antisense oligonucleotide targeting STAT3. Danvatirsen reduces the viability and promotes apoptosis of leukemia cell lines. Danvatirsen inhibits the expression of endogenous STAT3 and its downstream target genes, and reduces the proliferation and tumorigenicity of neuroblastoma and lymphoma cells. Danvatirsen inhibited tumor growth in mouse models of neuroblastoma, lymphoma, and non-small cell lung cancer. Danvatirsen achieves STAT3 mRNA and protein depletion in a mouse model of epidermoid carcinoma. Danvatirsen can be used in research related to lymphoma, myelodysplastic syndrome, acute myeloid leukemia, neuroblastoma and non-small cell lung cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD9150. CAS No. 1402357-06-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-145729.
DAO-IN-1
DAO-IN-1 is a potent inhibitor of D-amino acid oxidase (DAO) with an IC50 value of 269 nM. DAO is an enzyme responsible for D-serine metabolism, D-serine is a co-agonist of NMDA receptors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 51856-25-8. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-W037417.
DAOS
DAOS, a Trinder's reagent, is a novel highly water-soluble aniline derivative; are widely used in diagnostic tests and biochemical tests. Uses: Scientific research. Category: Signaling pathways. CAS No. 83777-30-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-15913.
1g Pack Size. Group: Biochemicals, Research Organics & Inorganics. Formula: C13H20NO6S ·Na. CAS No. 83777-30-4. Prepack ID 30235305-1g. Molecular Weight 341.36. See USA prepack pricing.
dAP2 (Nic)
dAP2 (Nic) presents itself as a worthy consideration in cholinergic signaling modulation. Its focus on targeting the nicotinic acetylcholine receptor exhibits prospects for application in treating perturbed signaling ailments like Alzheimer's disease and schizophrenia. Alternative Names: P1-[5'-(2'-Deoxy-adenosyl)] P2-[5'-(1-β D-Ribofuranosyl-nicotinamide)] diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C21H27N7O13P2 (free acid). Mole weight: 647.43 (free acid).
D-AP4
D-AP4. Group: Biochemicals. Grades: Purified. CAS No. 78739-01-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
D-AP5
D-AP5. Group: Biochemicals. Grades: Purified. CAS No. 79055-68-8. Pack Sizes: 1mg, 10mg, 50mg, 100mg. US Biological Life Sciences.
Worldwide
D-AP5
D-AP5 (D-APV) is a selective and competitive NMDA receptor antagonist with a Kd of 1.4 μM. D-AP5 (D-APV) inhibits the glutamate binding site of NMDA receptors[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-APV; D-2-Amino-5-phosphonovaleric acid. CAS No. 79055-68-8. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100714A.
D-AP7
D-AP7. Group: Biochemicals. Grades: Purified. CAS No. 81338-23-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
DAP-81
DAP-81 is a diaminopyrimidine derivative that targets PLKs, destabilizing kinetochore microtubules. Other spindle tubules are stabilized, resulting in monopolar mitotic spindles. In vitro, DAP-81 inhibits Plk1 at an IC50 of 0.9 nM. DAP-81 is currently in ongoing preclinical evaluations. Alternative Names: DAP81; DAP 81; DAP-81. N-(4-((4-((2-benzoylphenyl)amino)-5-nitropyrimidin-2-yl)amino)phenyl)acetamide. Grades: 98%. CAS No. 794466-17-4. Molecular formula: C25H20N6O4. Mole weight: 468.464.
dA(PAc)-3'-Methoxy Phosphoramidite
dA(PAc)-3'-Methoxy Phosphoramidite is a modified phosphoramidite designed for oligonucleotide synthesis. The adenine base is protected with a phenoxyacetyl (PAc) group at the N6 position, providing stability and preventing undesired side reactions during synthesis. The 3'-hydroxyl group is substituted with a methoxy group, enhancing the chemical stability and altering the structural properties of the resulting oligonucleotides. The phosphoramidite functionality at the 3' position ensures efficient coupling during automated oligonucleotide synthesis. This modification is particularly useful in applications requiring oligonucleotides with increased stability and resistance to enzymatic degradation, such as in therapeutic nucleic acids, antisense technologies, and advanced molecular biology research. Alternative Names: DMT-dA(PAc)-3'-Methoxy Phosphoramidite; 5'-O-DMTr-2'-deoxy-A(PAc)-3'-Methoxy-phosphoramidite; N6-Phenoxyacetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-adenosine-3'-Methoxy-phosphoramidite; dA(PAc) OMe-amidite. Grades: ≥95%. Molecular formula: C46H53N6O8P. Mole weight: 848.94.
Dapaconazole
Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1269726-67-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16719.
Dapagliflozin
Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine[1]. Dapagliflozin induces HIF1 expression and attenuates renal IR injury[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-512148. CAS No. 461432-26-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-10450.
Dapagliflozin
A sodium-glucose transporter 2 inhibitor. Group: Biochemicals. Alternative Names: (1S) -1, 5-Anhydro-1-C-[4-chloro-3-[ (4-ethoxyphenyl) methyl]phenyl]-D-glucitol; BMS 512148. Grades: Highly Purified. CAS No. 461432-26-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Dapagliflozin
Used (in the form of its propanediol monohydrate) to improve glycemic control, along with diet and exercise, in adults with type 2 diabetes. It has a role as a hypoglycemic agent and a sodium-glucose transport protein subtype 2 inhibitor. Category: Active pharmaceutical ingredients. Synonyms: BMS-512148;Forxiga;BMS 512148. Grades: USMF/DMF/China DMF/CDE. CAS No. 461432-26-8. Product ID: API461432268. Molecular formula: C21H25ClO6. Mole weight: 408.9. EINECS: 639-683-0. SMILES: CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)CO)O)O)O)Cl. Appearance: White to Pale Yellow Solid. Standard: In-house Facility GMP.
Dapagliflozin
Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Alternative Names: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; BMS 512148. Grades: >98%. CAS No. 461432-26-8. Molecular formula: C21H25ClO6. Mole weight: 408.87.
Dapagliflozin ((2S)-1,2-propanediol, hydrate)
Dapagliflozin ((2S)-1,2-propanediol, hydrate) is the S-enantiomer of Dapagliflozin 1,2-propanediol, hydrate. Dapagliflozin ((2S)-1,2-propanediol, hydrate), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine[1]. Dapagliflozin ((2S)-1,2-propanediol, hydrate) induces HIF1 expression and attenuates renal IR injury[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-512148 (2S)-1,2-propanediol, hydrate. CAS No. 960404-48-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10450A.
Dapagliflozin-3-O-β-D-glucuronide
Dapagliflozin-3-O-β-D-glucuronide (BMS-801576) is the metabolite of Dapagliflozin (HY-10450), and is formed in the liver and kidney by uridine diphosphate glucuronosyltransferase-1A9 (UGT1A9). Dapagliflozin is a selective inhibitor for SGLT2, that can be used to improve glycemic control and attenuate type 2 diabetes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-801576. CAS No. 1351438-75-9. Pack Sizes: 500 μg; 1 mg. Product ID: HY-125156.
Dapagliflozin 3-O-β-D-Glucuronide
Dapagliflozin 3-O-β-D-Glucuronide is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Alternative Names: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-3-O-β-D-glucopyranuronosyl-D-glucitol; D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-3-O-β-D-glucopyranuronosyl-, (1S)-; (2S,3S,4S,5R,6R)-6-(((2S,3S,4R,5R,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid; Dapagliflozin M-15 metabolite; Dapagliflozin 3-O-glucuronide. Grades: ≥95%. CAS No. 1351438-75-9. Molecular formula: C27H33ClO12. Mole weight: 585.00.
Dapagliflozin (BMS-512148)
Dapagliflozin is a potent and selective hSGLT2 inhibitor with EC50 of 1.1 nM, exhibiting 1200-fold selectivity over hSGLT1. Phase 4. Group: Inhibitors. Alternative Names: BMS-512148. CAS No. 461432-26-8. Pack Sizes: 50mg. Product ID: S1548. Formula: C21H25ClO6. Smiles: CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)CO)O)O)O)Cl. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Dapagliflozin-d5
Dapagliflozin-d5 is a deuterium labeled Dapagliflozin (HY-10450). Dapagliflozin is a competitive SGLT2 inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-512148-d5. CAS No. 1204219-80-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-10450S.
Dapagliflozin-[d5]
Dapagliflozin-[d5] is a labelled analogue of Dapagliflozin. Dapagliflozin is a selective sodium-glucose cotransporter-2 inhibitor that reduces renal glucose reabsorption and is used to treat patients with type 2 diabetes. Alternative Names: Dapagliflozin D5. Grades: 95% by HPLC; 95% atom D. CAS No. 1204219-80-6. Molecular formula: C21H20D5ClO6. Mole weight: 413.90.
Dapagliflozin Dimer
Dapagliflozin Dimer is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Alternative Names: Dapagliflozin Sugar Dimer. CAS No. 2452300-79-5. Molecular formula: C42H48Cl2O12. Mole weight: 815.73.
Dapagliflozin Furanose Isomer
Dapagliflozin Furanose Isomer is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Alternative Names: Dapagliflozin 1,4-Anhydro impurity; (1S)-1,4-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol. Grades: >95%. CAS No. 1469910-70-0. Molecular formula: C21H25ClO6. Mole weight: 408.87.
Dapagliflozin Hydroperoxide Impurity
Dapagliflozin Hydroperoxide Impurity. Uses: For analytical and research use. Alternative Names: (2S,3R,4R,5S,6R)-2-(4-chloro-3-((4-ethoxyphenyl)(hydroperoxy)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 2452300-94-4. Molecular formula: C21H25ClO8. Mole weight: 440.87. Catalog: APB2452300944.
Dapagliflozin impurity
Dapagliflozin impurity is an enantiomer of Dapagliflozin which is a sodium-glucose transporter 2 inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 960404-86-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-128723.
Dapagliflozin Impurity 10
Dapagliflozin Impurity 10. Uses: For analytical and research use. Alternative Names: (3R,4R,5R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol. CAS No. 2271248-78-1. Molecular formula: C21H25ClO6. Mole weight: 408.87. Catalog: APB2271248781.
Dapagliflozin Impurity 100
Dapagliflozin Impurity 100. Uses: For analytical and research use. Alternative Names: (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol. Molecular formula: C20H23ClO7. Mole weight: 410.85. Catalog: APB04945.
Dapagliflozin Impurity 101
Dapagliflozin Impurity 101. Uses: For analytical and research use. Alternative Names: (2S,3R,4S,5R,6R)-6-(acetoxymethyl)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triyl triacetate. CAS No. 714269-58-6. Molecular formula: C30H35ClO11. Mole weight: 607.05. Catalog: APB714269586.
Dapagliflozin Impurity 102
Dapagliflozin Impurity 102. Uses: For analytical and research use. CAS No. 2770409-19-1. Molecular formula: C31H37ClO10. Mole weight: 605.08. Catalog: APB2770409191.
Dapagliflozin Impurity 102
Dapagliflozin Impurity 102. Uses: For analytical and research use. Alternative Names: 4-chloro-3-(4-ethoxybenzyl)phenol. CAS No. 1408077-50-8. Molecular formula: C15H15ClO2. Mole weight: 262.73. Catalog: APB1408077508.
Dapagliflozin Impurity 11
Dapagliflozin Impurity 11. Uses: For analytical and research use. Alternative Names: (2S,3R,4R,5R)-1-(4-chloro-3-(4-ethoxybenzyl)phenyl)hexane-1,2,3,4,5,6-hexaol. CAS No. 2100872-88-4. Molecular formula: C21H27ClO7. Mole weight: 426.89. Catalog: APB2100872884.