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Danusertib is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity. Aurora kinase inhibitor PHA-739358 binds to and inhibits the Aurora kinases, which may result in cell growth arrest and apoptosis in tumor cells in which Aurora kinases are overexpressed. This agent may preferentially bind to and inhibit Aurora B kinase. Aurora kinases, a family of serine-threonine kinases, are important regulators of cellular proliferation and division. Synonyms: PHA739358; PHA-739358; PHA 739358; Danusertib. CAS No. 827318-97-8. Molecular formula: C26H30N6O3. Mole weight: 474.55.
Danusertib
An Aurora kinase inhibitor, used to treat patients with chromic myeloid leukemia. Group: Biochemicals. Alternative Names: 4- (4-Methyl-1-piperazinyl) -N- [1, 4, 5, 6-tetrahydro-5- [ (2R) -2-methoxy-2-phenylacetyl]pyrrolo [3, 4-c]pyrazol-3-yl]benzamide; PHA 739358. Grades: Highly Purified. CAS No. 827318-97-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Danusertib
Danusertib is a pyrrolo-pyrazole and aurora kinase inhibitor with IC50 of 13, 79, and 61 nM for Aurora A, B, and C, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PHA-739358. CAS No. 827318-97-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10179.
Danvatirsen
Danvatirsen (AZD9150) is an antisense oligonucleotide targeting STAT3. Danvatirsen reduces the viability and promotes apoptosis of leukemia cell lines. Danvatirsen inhibits the expression of endogenous STAT3 and its downstream target genes, and reduces the proliferation and tumorigenicity of neuroblastoma and lymphoma cells. Danvatirsen inhibited tumor growth in mouse models of neuroblastoma, lymphoma, and non-small cell lung cancer. Danvatirsen achieves STAT3 mRNA and protein depletion in a mouse model of epidermoid carcinoma. Danvatirsen can be used in research related to lymphoma, myelodysplastic syndrome, acute myeloid leukemia, neuroblastoma and non-small cell lung cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD9150. CAS No. 1402357-06-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-145729.
DAO-IN-1
DAO-IN-1 is a potent inhibitor of D-amino acid oxidase (DAO) with an IC50 value of 269 nM. DAO is an enzyme responsible for D-serine metabolism, D-serine is a co-agonist of NMDA receptors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 51856-25-8. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-W037417.
DAOS
DAOS, a Trinder's reagent, is a novel highly water-soluble aniline derivative; are widely used in diagnostic tests and biochemical tests. Uses: Scientific research. Category: Signaling pathways. CAS No. 83777-30-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-15913.
1g Pack Size. Group: Biochemicals, Research Organics & Inorganics. Formula: C13H20NO6S ·Na. CAS No. 83777-30-4. Prepack ID 30235305-1g. Molecular Weight 341.36. See USA prepack pricing.
dAP2 (Nic)
dAP2 (Nic) presents itself as a worthy consideration in cholinergic signaling modulation. Its focus on targeting the nicotinic acetylcholine receptor exhibits prospects for application in treating perturbed signaling ailments like Alzheimer's disease and schizophrenia. Synonyms: P1-[5'-(2'-Deoxy-adenosyl)] P2-[5'-(1-β D-Ribofuranosyl-nicotinamide)] diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C21H27N7O13P2 (free acid). Mole weight: 647.43 (free acid).
D-AP4
D-AP4 has been found to be an excitatory amino acid receptor antagonist as well as an agonist at the quisqualate-sensitized AP6 site. Synonyms: D-AP4; D AP4; DAP4; D-(-)-2-Amino-4-phosphonobutyric acid. Grade: ≥98% by HPLC. CAS No. 78739-01-2. Molecular formula: C4H10NO5P. Mole weight: 183.10.
D-AP4
D-AP4. Group: Biochemicals. Grades: Purified. CAS No. 78739-01-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
D-AP5
D-AP5, a more active form of AP5, has been found to be an NMDA antagonist. Synonyms: D-(-)-2-Amino-5-phosphonopentanoic acid. Grade: ≥99% by HPLC. CAS No. 79055-68-8. Molecular formula: C5H12NO5P. Mole weight: 197.13.
D-AP5
D-AP5 (D-APV) is a selective and competitive NMDA receptor antagonist with a Kd of 1.4 μM. D-AP5 (D-APV) inhibits the glutamate binding site of NMDA receptors[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-APV; D-2-Amino-5-phosphonovaleric acid. CAS No. 79055-68-8. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100714A.
D-AP5
D-AP5. Group: Biochemicals. Grades: Purified. CAS No. 79055-68-8. Pack Sizes: 1mg, 10mg, 50mg, 100mg. US Biological Life Sciences.
Worldwide
D-AP7
D-AP7 is a selective NMDA receptor antagonist that inhibits the glutamate binding site and activation of NMDA receptor. It is the 8-Bromo-cGMP and the more active form of DL-AP7. It shows anticonvulsant and anxiogenic-like effects. Synonyms: Heptanoic acid, 2-amino-7-phosphono-, (2R)-; D-AP7; D(-)-2-Amino-7-phosphonoheptanoic acid; (2R)-2-amino-7-phosphonoheptanoic acid. CAS No. 81338-23-0. Molecular formula: C7H16NO5P. Mole weight: 225.181.
D-AP7
D-AP7. Group: Biochemicals. Grades: Purified. CAS No. 81338-23-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
DAP-81
DAP-81 is a diaminopyrimidine derivative that targets PLKs, destabilizing kinetochore microtubules. Other spindle tubules are stabilized, resulting in monopolar mitotic spindles. In vitro, DAP-81 inhibits Plk1 at an IC50 of 0.9 nM. DAP-81 is currently in ongoing preclinical evaluations. Synonyms: DAP81; DAP 81; DAP-81. N-(4-((4-((2-benzoylphenyl)amino)-5-nitropyrimidin-2-yl)amino)phenyl)acetamide. Grade: 98%. CAS No. 794466-17-4. Molecular formula: C25H20N6O4. Mole weight: 468.464.
dA(PAc)-3'-Methoxy Phosphoramidite
dA(PAc)-3'-Methoxy Phosphoramidite is a modified phosphoramidite designed for oligonucleotide synthesis. The adenine base is protected with a phenoxyacetyl (PAc) group at the N6 position, providing stability and preventing undesired side reactions during synthesis. The 3'-hydroxyl group is substituted with a methoxy group, enhancing the chemical stability and altering the structural properties of the resulting oligonucleotides. The phosphoramidite functionality at the 3' position ensures efficient coupling during automated oligonucleotide synthesis. This modification is particularly useful in applications requiring oligonucleotides with increased stability and resistance to enzymatic degradation, such as in therapeutic nucleic acids, antisense technologies, and advanced molecular biology research. Synonyms: DMT-dA(PAc)-3'-Methoxy Phosphoramidite; 5'-O-DMTr-2'-deoxy-A(PAc)-3'-Methoxy-phosphoramidite; N6-Phenoxyacetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-adenosine-3'-Methoxy-phosphoramidite; dA(PAc) OMe-amidite. Grade: ≥95%. Molecular formula: C46H53N6O8P. Mole weight: 848.94.
Dapaconazole
Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1269726-67-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16719.
Dapagliflozin
Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; BMS 512148. Grade: >98%. CAS No. 461432-26-8. Molecular formula: C21H25ClO6. Mole weight: 408.87.
Dapagliflozin
A sodium-glucose transporter 2 inhibitor. Group: Biochemicals. Alternative Names: (1S) -1, 5-Anhydro-1-C-[4-chloro-3-[ (4-ethoxyphenyl) methyl]phenyl]-D-glucitol; BMS 512148. Grades: Highly Purified. CAS No. 461432-26-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Dapagliflozin
Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine[1]. Dapagliflozin induces HIF1 expression and attenuates renal IR injury[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-512148. CAS No. 461432-26-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-10450.
Dapagliflozin
Used (in the form of its propanediol monohydrate) to improve glycemic control, along with diet and exercise, in adults with type 2 diabetes. It has a role as a hypoglycemic agent and a sodium-glucose transport protein subtype 2 inhibitor. Category: Active pharmaceutical ingredients. Synonyms: BMS-512148;Forxiga;BMS 512148. Grades: USMF/DMF/China DMF/CDE. CAS No. 461432-26-8. Product ID: API461432268. Molecular formula: C21H25ClO6. Mole weight: 408.9. EINECS: 639-683-0. SMILES: CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)CO)O)O)O)Cl. Appearance: White to Pale Yellow Solid. Standard: In-house Facility GMP.
Dapagliflozin 2-O-β-D-glucuronide
Dapagliflozin 2-O-β-D-Glucuronide is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-2-O-β-D-glucopyranuronosyl-D-glucitol. Grade: >95%. CAS No. 2078003-84-4. Molecular formula: C27H33ClO12. Mole weight: 585.00.
Dapagliflozin ((2S)-1,2-propanediol, hydrate)
Dapagliflozin ((2S)-1,2-propanediol, hydrate) is the S-enantiomer of Dapagliflozin 1,2-propanediol, hydrate. Dapagliflozin ((2S)-1,2-propanediol, hydrate), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine[1]. Dapagliflozin ((2S)-1,2-propanediol, hydrate) induces HIF1 expression and attenuates renal IR injury[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-512148 (2S)-1,2-propanediol, hydrate. CAS No. 960404-48-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10450A.
Dapagliflozin-3-O-β-D-glucuronide
Dapagliflozin-3-O-β-D-glucuronide (BMS-801576) is the metabolite of Dapagliflozin (HY-10450), and is formed in the liver and kidney by uridine diphosphate glucuronosyltransferase-1A9 (UGT1A9). Dapagliflozin is a selective inhibitor for SGLT2, that can be used to improve glycemic control and attenuate type 2 diabetes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-801576. CAS No. 1351438-75-9. Pack Sizes: 500 μg; 1 mg. Product ID: HY-125156.
Dapagliflozin 3-O-β-D-Glucuronide
Dapagliflozin 3-O-β-D-Glucuronide is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-3-O-β-D-glucopyranuronosyl-D-glucitol; D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-3-O-β-D-glucopyranuronosyl-, (1S)-; (2S,3S,4S,5R,6R)-6-(((2S,3S,4R,5R,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid; Dapagliflozin M-15 metabolite; Dapagliflozin 3-O-glucuronide. Grade: ≥95%. CAS No. 1351438-75-9. Molecular formula: C27H33ClO12. Mole weight: 585.00.
Dapagliflozin (BMS-512148)
Dapagliflozin is a potent and selective hSGLT2 inhibitor with EC50 of 1.1 nM, exhibiting 1200-fold selectivity over hSGLT1. Phase 4. Group: Inhibitors. Alternative Names: BMS-512148. CAS No. 461432-26-8. Pack Sizes: 50mg. Product ID: S1548. Formula: C21H25ClO6. Smiles: CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)CO)O)O)O)Cl. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Dapagliflozin C1,C2 Epimer
Dapagliflozin C1,C2 Epimer is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Molecular formula: C21H25ClO6. Mole weight: 408.87.
Dapagliflozin C1,C2 Epimer Tetraacetate
Dapagliflozin C1,C2 Epimer Tetraacetate is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Molecular formula: C29H33ClO10. Mole weight: 577.02.
Dapagliflozin C2 Epimer Tetraacetate
Dapagliflozin C2 Epimer Tetraacetate is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Molecular formula: C29H33ClO10. Mole weight: 577.02.
Dapagliflozin-d5
Dapagliflozin-d5 is a deuterium labeled Dapagliflozin (HY-10450). Dapagliflozin is a competitive SGLT2 inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-512148-d5. CAS No. 1204219-80-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-10450S.
Dapagliflozin-[d5]
Dapagliflozin-[d5] is a labelled analogue of Dapagliflozin. Dapagliflozin is a selective sodium-glucose cotransporter-2 inhibitor that reduces renal glucose reabsorption and is used to treat patients with type 2 diabetes. Synonyms: Dapagliflozin D5. Grade: 95% by HPLC; 95% atom D. CAS No. 1204219-80-6. Molecular formula: C21H20D5ClO6. Mole weight: 413.90.
Dapagliflozin Dimer
Dapagliflozin Dimer is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin Sugar Dimer. CAS No. 2452300-79-5. Molecular formula: C42H48Cl2O12. Mole weight: 815.73.
Dapagliflozin Furanose Isomer
Dapagliflozin Furanose Isomer is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin 1,4-Anhydro impurity; (1S)-1,4-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol. Grade: >95%. CAS No. 1469910-70-0. Molecular formula: C21H25ClO6. Mole weight: 408.87.
Dapagliflozin Hydroperoxide Impurity
Dapagliflozin Hydroperoxide Impurity. Uses: For analytical and research use. Alternative Names: (2S,3R,4R,5S,6R)-2-(4-chloro-3-((4-ethoxyphenyl)(hydroperoxy)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 2452300-94-4. Molecular formula: C21H25ClO8. Mole weight: 440.87. Catalog: APB2452300944.
Dapagliflozin impurity
Dapagliflozin impurity is an enantiomer of Dapagliflozin which is a sodium-glucose transporter 2 inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 960404-86-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-128723.
Dapagliflozin Impurity 1
Dapagliflozin Impurity 1 is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin Bromo Keto Impurity; (5-Bromo-2-Chlorophenyl)(2-Ethoxyphenyl)Methanone. Grade: > 95%. CAS No. 1404477-10-6. Molecular formula: C15H12BrClO2. Mole weight: 339.61.
Dapagliflozin Impurity 10
Dapagliflozin Impurity 10. Uses: For analytical and research use. Alternative Names: (3R,4R,5R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol. CAS No. 2271248-78-1. Molecular formula: C21H25ClO6. Mole weight: 408.87. Catalog: APB2271248781.
Dapagliflozin Impurity 10
Dapagliflozin Impurity 10 is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin Hydroxy Impurity; 1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-α-D-glucopyranose. Grade: >90%. CAS No. 960404-86-8. Molecular formula: C21H25ClO7. Mole weight: 424.87.
Dapagliflozin Impurity 100
Dapagliflozin Impurity 100. Uses: For analytical and research use. Alternative Names: (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol. Molecular formula: C20H23ClO7. Mole weight: 410.85. Catalog: APB04945.
Dapagliflozin Impurity 101
Dapagliflozin Impurity 101. Uses: For analytical and research use. Alternative Names: (2S,3R,4S,5R,6R)-6-(acetoxymethyl)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triyl triacetate. CAS No. 714269-58-6. Molecular formula: C30H35ClO11. Mole weight: 607.05. Catalog: APB714269586.
Dapagliflozin Impurity 102
Dapagliflozin Impurity 102. Uses: For analytical and research use. Alternative Names: 4-chloro-3-(4-ethoxybenzyl)phenol. CAS No. 1408077-50-8. Molecular formula: C15H15ClO2. Mole weight: 262.73. Catalog: APB1408077508.
Dapagliflozin Impurity 102
Dapagliflozin Impurity 102. Uses: For analytical and research use. CAS No. 2770409-19-1. Molecular formula: C31H37ClO10. Mole weight: 605.08. Catalog: APB2770409191.
Dapagliflozin Impurity 11
Dapagliflozin Impurity 11 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin Dimer. Molecular formula: C42H48Cl2O12. Mole weight: 815.73.
Dapagliflozin Impurity 11
Dapagliflozin Impurity 11. Uses: For analytical and research use. Alternative Names: (2S,3R,4R,5R)-1-(4-chloro-3-(4-ethoxybenzyl)phenyl)hexane-1,2,3,4,5,6-hexaol. CAS No. 2100872-88-4. Molecular formula: C21H27ClO7. Mole weight: 426.89. Catalog: APB2100872884.
Dapagliflozin Impurity 12
Dapagliflozin Impurity 12 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Molecular formula: C18H42O6Si4. Mole weight: 466.86.
Dapagliflozin Impurity 12
Dapagliflozin Impurity 12. Uses: For analytical and research use. Alternative Names: (2-chloro-5-iodophenyl)(4-ethoxyphenyl)methanone. CAS No. 1103738-26-6. Molecular formula: C15H12ClIO2. Mole weight: 386.61. Catalog: APB1103738266.
Dapagliflozin Impurity 13
Dapagliflozin Impurity 13 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Molecular formula: C21H25ClO6. Mole weight: 408.88.
Dapagliflozin Impurity 13
Dapagliflozin Impurity 13. Uses: For analytical and research use. CAS No. 1938090-31-3. Molecular formula: C21H27ClO7. Mole weight: 426.89. Catalog: APB1938090313.
Dapagliflozin Impurity 14
Dapagliflozin Impurity 14. Uses: For analytical and research use. Alternative Names: (2R,3R,4R,5S,6R)-2-(4-chloro-3-(2-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Molecular formula: C21H25ClO6. Mole weight: 408.87. Catalog: APB04836.
Dapagliflozin Impurity 14
Dapagliflozin Impurity 14 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Ent-Dapagliflozin. Molecular formula: C21H25ClO6. Mole weight: 408.87.
Dapagliflozin Impurity 16
Dapagliflozin Impurity 16 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 1α-Methyl Dapagliflozin; Dapagliflozin Methoxy Pyranose Impurity; (2S,3R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol; Methyl 1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-α-D-glucopyranoside; α-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-; Methoxy Dapagliflozin. Grade: >95%. CAS No. 714269-57-5. Molecular formula: C22H27ClO7. Mole weight: 438.90.
Dapagliflozin Impurity 16
Dapagliflozin Impurity 16. Uses: For analytical and research use. Alternative Names: (2-chloro-5-iodophenyl)(4-ethoxyphenyl)methanol. Molecular formula: C15H14ClIO2. Mole weight: 388.63. Catalog: APB04837.
Dapagliflozin Impurity 17
Dapagliflozin Impurity 17 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 1,4-Dibromo-2-[(4-ethoxyphenyl)methyl]benzene. Grade: >95%. CAS No. 1807632-93-4. Molecular formula: C15H14Br2O. Mole weight: 370.08.
Dapagliflozin Impurity 17
Dapagliflozin Impurity 17. Uses: For analytical and research use. CAS No. 103-73-1. Molecular formula: C8H10O. Mole weight: 122.16. Catalog: APB103731.
Dapagliflozin Impurity 17
Dapagliflozin Impurity 17. Uses: For analytical and research use. Alternative Names: (3R,4R,5R)-5-((R)-1,2-dihydroxyethyl)-3,4-dihydroxydihydrofuran-2(3H)-one. CAS No. 1198-69-2. Molecular formula: C6H10O6. Mole weight: 178.14. Catalog: APB1198692.
Dapagliflozin Impurity 18
Dapagliflozin Impurity 18. Uses: For analytical and research use. Alternative Names: (3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-one. Molecular formula: C6H10O6. Mole weight: 178.14. Catalog: APB04835.
Dapagliflozin Impurity 19
Dapagliflozin Impurity 19. Uses: For analytical and research use. CAS No. 2262460-67-1. Molecular formula: C20H21ClO7. Mole weight: 408.83. Catalog: APB2262460671.
Dapagliflozin Impurity 19
Dapagliflozin Impurity 19. Uses: For analytical and research use. Alternative Names: (3R,4S,5R,6R)-3,4,5-tris((trimethylsilyl)oxy)-6-(((trimethylsilyl)oxy)methyl)tetrahydro-2H-pyran-2-one. CAS No. 32384-65-9. Molecular formula: C18H42O6Si4. Mole weight: 466.86. Catalog: APB32384659.
Dapagliflozin Impurity 2
Dapagliflozin Impurity 2 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 4-bromo-1-chloro-2-(2-ethoxybenzyl)benzene. Grade: >95%. CAS No. 1830346-16-1. Molecular formula: C15H14BrClO. Mole weight: 325.63.
Dapagliflozin Impurity 20
Dapagliflozin Impurity 20. Uses: For analytical and research use. Alternative Names: (2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate. CAS No. 461432-25-7. Molecular formula: C29H33ClO10. Mole weight: 577.02. Catalog: APB461432257.
Dapagliflozin Impurity 20
Dapagliflozin Impurity 20. Uses: For analytical and research use. CAS No. 2040305-09-5. Molecular formula: C29H33ClO10. Mole weight: 577.02. Catalog: APB2040305095.
Dapagliflozin Impurity 20
Dapagliflozin Impurity 20 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 4-Bromo-1-chloro-2-(4-methoxybenzyl)benzene; 2-(4-methoxybenzyl)-4-bromo-1-chlorobenzene. Grade: >95%. CAS No. 333361-51-6. Molecular formula: C14H12BrClO. Mole weight: 311.6.
Dapagliflozin Impurity 21
Dapagliflozin Impurity 21 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin Dibromo compound. Molecular formula: C29H33ClO10. Mole weight: 577.02.
Dapagliflozin Impurity 21
Dapagliflozin Impurity 21. Uses: For analytical and research use. CAS No. 1443341-94-3. Molecular formula: C27H31ClO9. Mole weight: 534.99. Catalog: APB1443341943.
Dapagliflozin Impurity 21
Dapagliflozin Impurity 21. Uses: For analytical and research use. Alternative Names: (2S,3R,4R,5S,6R)-2-(4-chloro-3-(2-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 2040305-05-1. Molecular formula: C21H25ClO6. Mole weight: 408.87. Catalog: APB2040305051.
Dapagliflozin Impurity 22
Dapagliflozin Impurity 22. Uses: For analytical and research use. Alternative Names: (1S,2S,3R,4R,5R)-1-(4-chloro-3-(4-ethoxybenzyl)phenyl)hexane-1,2,3,4,5,6-hexaol. Molecular formula: C21H27ClO7. Mole weight: 426.89. Catalog: APB04978.
Dapagliflozin Impurity 23
Dapagliflozin Impurity 23. Uses: For analytical and research use. CAS No. 1079083-63-8. Molecular formula: C27H29ClO10. Mole weight: 548.97. Catalog: APB1079083638.
Dapagliflozin Impurity 23
Dapagliflozin Impurity 23. Uses: For analytical and research use. Alternative Names: ((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl acetate. CAS No. 1632287-34-3. Molecular formula: C23H27ClO7. Mole weight: 450.91. Catalog: APB1632287343.
Dapagliflozin Impurity 24
Dapagliflozin Impurity 24 is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (1S)-1,5-anhydro-1-C-[4-Chloro-3-[(4-ethoxyphenyl)hydroxymethyl]phenyl]-D-glucitol; BMS-639432. Grade: >95%. CAS No. 1204222-85-4. Molecular formula: C21H25ClO7. Mole weight: 424.87.