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Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 25316-40-9. Molecular formula: C27H30ClNO11. Purity: 0.9958. Product ID: ACM25316409-1. Alfa Chemistry ISO 9001:2015 Certified.
Doxorubicin hydrochloride
25mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Organics, Research Organics & Inorganics. Formula: C27H29NO11 ·HCl. CAS No. 25316-40-9. Prepack ID 57489114-25mg. Molecular Weight 579.98. See USA prepack pricing.
Doxorubicin hydrochloride
100mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Organics, Research Organics & Inorganics. Formula: C27H29NO11 ·HCl. CAS No. 25316-40-9. Prepack ID 57489114-100mg. Molecular Weight 579.98. See USA prepack pricing.
Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride; ADR), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC 50 s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Hydroxydaunorubicin hydrochloride; ADR. CAS No. 25316-40-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15142.
Doxorubicin Hydrochloride
Used as an antineoplastic. Group: Biochemicals. Alternative Names: (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione Hydrochloride; Adriacin; Adriblastina; Adriamycin; Caelyx. Grades: Highly Purified. CAS No. 25316-40-9. Pack Sizes: 25mg. US Biological Life Sciences.
The hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids; the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects. Group: Biochemicals. Alternative Names: Adriacin, Adriblastina, Adriamycin, Caelyx. Grades: Highly Purified. CAS No. 25316-40-9. Pack Sizes: 25mg, 100mg, 250mg. US Biological Life Sciences.
Worldwide
Doxorubicin Impurity 1
Doxorubicin Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6,8,11-trihydroxy-1-methoxytetracene-5,12-dione. CAS No. 64845-67-6. Molecular Formula: C19H12O6. Mole Weight: 336.06. Catalog: APB64845676.
Doxorubicin Impurity 1
Doxorubicin Impurity 1 is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: Doxorubicin Impurity; 6,8,10,11-Tetrahydroxy-1-methoxy-5,12-naphthacenedione; 7,8-Desacetyl-9,10-dehydro Daunorubicinone; 5,12-Naphthacenedione, 6,8,10,11-tetrahydroxy-1-methoxy-; Xanthone Impurity 13. Grades: > 95%. CAS No. 1159977-24-8. Molecular formula: C19H12O7. Mole weight: 352.29.
Doxorubicin Impurity 10
Doxorubicin Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (8R,10S)-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-hydroperoxy-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione. CAS No. 2183522-37-2. Molecular Formula: C25H27NO11. Mole Weight: 517.16. Catalog: APB2183522372.
Doxorubicin Impurity 14
Doxorubicin Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 92999-26-3. Molecular Formula: C26H30ClNO9. Mole Weight: 535.97. Catalog: APB92999263.
Doxorubicin Impurity 18
Doxorubicin Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 80948-70-5. Molecular Formula: C21H16O8. Mole Weight: 396.35. Catalog: APB80948705.
Doxorubicin Impurity 19
Doxorubicin Impurity 19. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H16O8. Mole Weight: 396.35. Catalog: APB07589.
Doxorubicin Impurity 2
Doxorubicin Impurity 2 is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: Doxorubicin Impurity-?; 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione; 5,12-Naphthacenedione, 6,8,11-trihydroxy-1-methoxy-; 7,8-Dehydro-9,10-desacetyldoxorubicinone; 7,8-Dhda-DR; 1-Methoxy-6,8,11-trihydroxynaphthacene-5,12-dione. Grades: >95%. CAS No. 64845-67-6. Molecular formula: C19H12O6. Mole weight: 336.30.
Doxorubicin Impurity 20
Doxorubicin Impurity 20. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H27NO11. Mole Weight: 529.5. Catalog: APB07590.
Doxorubicin Impurity 21
Doxorubicin Impurity 21. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H25NO10. Mole Weight: 511.48. Catalog: APB07591.
Doxorubicin Impurity 22
Doxorubicin Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 69429-21-6. Molecular Formula: C26H27NO11. Mole Weight: 529.5. Catalog: APB69429216.
Doxorubicin Impurity 23
Doxorubicin Impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 80996-23-2. Molecular Formula: C27H27NO10. Mole Weight: 525.51. Catalog: APB80996232.
Doxorubicin Impurity 26
Doxorubicin Impurity 26. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C28H31NO12. Mole Weight: 573.55. Catalog: APB07592.
Doxorubicin Impurity 27
Doxorubicin Impurity 27. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C28H29NO12. Mole Weight: 571.54. Catalog: APB07593.
Doxorubicin Impurity 28
Doxorubicin Impurity 28. Uses: For analytical and research use. Group: Impurity standards. CAS No. 286010-07-9. Molecular Formula: C29H36ClNO12. Mole Weight: 626.05. Catalog: APB286010079.
Doxorubicin Impurity 29
Doxorubicin Impurity 29. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C54H58N2O22. Mole Weight: 1087.05. Catalog: APB07595.
Doxorubicin Impurity 3
Doxorubicin Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C20H12O7. Mole Weight: 364.31. Catalog: APB07586.
Doxorubicin Impurity 30
Doxorubicin Impurity 30. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C64H74N2O24. Mole Weight: 1255.29. Catalog: APB07594.
Doxorubicin Impurity 31
Doxorubicin Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C33H37NO13. Mole Weight: 655.65. Catalog: APB07596.
Doxorubicin Impurity 32
Doxorubicin Impurity 32. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C31H35NO12. Mole Weight: 613.62. Catalog: APB07598.
Doxorubicin Impurity 33
Doxorubicin Impurity 33. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C32H35NO12. Mole Weight: 625.63. Catalog: APB07597.
Doxorubicin Impurity 35
Doxorubicin Impurity 35. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C74H90N2O26. Mole Weight: 1423.52. Catalog: APB07599.
Doxorubicin Impurity 36
Doxorubicin Impurity 36. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C34H43NO13. Mole Weight: 673.71. Catalog: APB07600.
Doxorubicin Impurity 37
Doxorubicin Impurity 37. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H26O10. Mole Weight: 498.48. Catalog: APB07602.
Doxorubicin Impurity 38
Doxorubicin Impurity 38. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H26O10. Mole Weight: 498.48. Catalog: APB07601.
Doxorubicin Impurity 39
Doxorubicin Impurity 39. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C32H37NO12. Mole Weight: 627.64. Catalog: APB07603.
Doxorubicin Impurity 4
Doxorubicin Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H18O9. Mole Weight: 414.37. Catalog: APB07587.
Doxorubicin Impurity 40
Doxorubicin Impurity 40. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C32H37NO12. Mole Weight: 627.64. Catalog: APB07604.
Doxorubicin Impurity 41
Doxorubicin Impurity 41. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C54H58N2O22. Mole Weight: 1087.5. Catalog: APB07605.
Doxorubicin Impurity 42
Doxorubicin Impurity 42. Uses: For analytical and research use. Group: Impurity standards. CAS No. 71800-89-0. Molecular Formula: C27H29NO10. Mole Weight: 527.53. Catalog: APB71800890.
Doxorubicin Impurity 43
Doxorubicin Impurity 43. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C20H12O7. Mole Weight: 364.31. Catalog: APB07607.
Doxorubicin Impurity 44
Doxorubicin Impurity 44. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C54H56N2O21. Mole Weight: 1069.04. Catalog: APB07606.
Doxorubicin Impurity 45
Doxorubicin Impurity 45. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C27H27Cl2NO10. Mole Weight: 596.41. Catalog: APB07608.
Doxorubicin Impurity 46
Doxorubicin Impurity 46. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C19H10O8. Mole Weight: 366.28. Catalog: APB07610.
Doxorubicin Impurity 47
Doxorubicin Impurity 47. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C27H29NO12. Mole Weight: 559.52. Catalog: APB07609.
Doxorubicin Impurity 49
Doxorubicin Impurity 49. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C27H28ClNO11. Mole Weight: 577.97. Catalog: APB07611.
Doxorubicin Impurity 5
Doxorubicin Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C20H12O7. Mole Weight: 364.31. Catalog: APB07588.
Doxorubicin Impurity50
Doxorubicin Impurity50. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C55H60N2O21. Mole Weight: 1085.08. Catalog: APB07612.
Doxorubicin Impurity51
Doxorubicin Impurity51. Uses: For analytical and research use. Group: Impurity standards. CAS No. 73952-94-0. Molecular Formula: C27H30ClNO10. Mole Weight: 563.98. Catalog: APB73952940.
Doxorubicin Impurity52
Doxorubicin Impurity52. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C54H58N2O22. Mole Weight: 1087.05. Catalog: APB07613.
Doxorubicin Impurity53
Doxorubicin Impurity53. Uses: For analytical and research use. Group: Impurity standards. CAS No. 201278-93-5. Molecular Formula: C54H54N2O21. Mole Weight: 1067.02. Catalog: APB201278935.
Doxorubicin Impurity 54
Doxorubicin Impurity 54. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H25NO10. Mole Weight: 511.48. Catalog: APB07615.
Doxorubicin Impurity 55
Doxorubicin Impurity 55. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H26ClNO10. Mole Weight: 547.94. Catalog: APB07614.
Doxorubicin Impurity 56
Doxorubicin Impurity 56. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C54H56N2O21. Mole Weight: 1069.04. Catalog: APB07618.
Doxorubicin Impurity 57
Doxorubicin Impurity 57. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C54H54N2O21. Mole Weight: 1067.02. Catalog: APB07617.
Doxorubicin Impurity 58
Doxorubicin Impurity 58. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C54H56N2O21. Mole Weight: 1069.04. Catalog: APB07616.
Doxorubicin Impurity 59
Doxorubicin Impurity 59. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C54H58N2O22. Mole Weight: 1087.05. Catalog: APB07619.
Doxorubicin Impurity 6
Doxorubicin Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 58199-98-7. Molecular Formula: C20H16O9. Mole Weight: 400.34. Catalog: APB58199987.
Doxorubicin Impurity 6
Doxorubicin Impurity 6 is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: 9-Carboxy Doxorubicin Impurity; (2S,4S)-4-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-2-carboxylic acid; (2S,4S)-4-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenecarboxylic Acid; 2-Naphthacenecarboxylic acid, 4-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-, (2S-cis)-; 8-Desacetyl-8-carboxy Daunorubicin. Grades: > 95%. CAS No. 69429-21-6. Molecular formula: C26H27NO11. Mole weight: 529.49.
Doxorubicin Impurity 7
Doxorubicin Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6,11-dihydroxy-8-(2-hydroxyacetyl)-1-methoxytetracene-5,12-dione. CAS No. 105612-58-6. Molecular Formula: C21H14O7. Mole Weight: 378.07. Catalog: APB105612586.
Doxorubicin Impurity 7
Doxorubicin Impurity 7 is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: 7,8,9,10-Dehydro Doxorubicinone; 8-Glycoloyl-6,10,11-trihydroxy-1-methoxy-5,12-tetracenedione; 5,12-Naphthacenedione, 6,10,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-; 6,10,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxytetracene-5,12-dione. Grades: > 95%. CAS No. 1159977-23-7. Molecular formula: C21H14O8. Mole weight: 394.33.
Doxorubicin Impurity 8
Doxorubicin Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5,12-dihydroxy-7-methoxy-3,4-dihydrotetracene-2,6,11(1H)-trione. CAS No. 59325-97-2. Molecular Formula: C19H14O6. Mole Weight: 338.08. Catalog: APB59325972.
Doxorubicin Impurity 9
Doxorubicin Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-7-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,9,11-trihydroxy-4-methoxy-7,8-dihydrotetracene-5,12-dione. CAS No. 2183522-38-3. Molecular Formula: C25H25NO9. Mole Weight: 483.15. Catalog: APB2183522383.
Doxorubicin Impurity B
Cas No. 106401-68-7.
Doxorubicin Liposome (PEGylated)
This formulation of doxorubicin liposome is PEGylated, which is only for research purposes and for the injection to laboratory animals. Doxorubicin drug is encapsulated into the liposome using remote loading by ammonium sulfate gradient. The formulation is ready for injection. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes.
Doxorubicinol
Doxorubicinol. Uses: For analytical and research use. Group: Impurity standards. CAS No. 54193-28-1. Molecular Formula: C27H31NO11. Mole Weight: 545.54. Catalog: APB54193281.
Doxorubicinol Citrate (Mixture of Diastereomers)
A metabolite of Doxorubicin as neoplasm inhibitor. Group: Biochemicals. Alternative Names: (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-[1,2-dihydroxyethyl]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Citrate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Doxorubicinol hydrochloride
Doxorubicinol hydrochloride (13-Dihydroadriamycin hydrochloride) is a secondary alcohol metabolite of Doxorubicin [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 13-Dihydroadriamycin hydrochloride. CAS No. 63950-05-0. Pack Sizes: 1 mg. Product ID: HY-G0022.
Doxorubicinol hydrochloride
Doxorubicinol is the major metabolite of doxorubicin, which inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. Synonyms: (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-[(1S)-1,2-dihydroxyethyl]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Hydrochloride; Adriamycinol Hydrochloride; 13-Dihydrodoxorubicin Hydrochloride; (1S,3S)-3-[(1S)-1,2-Dihydroxyethyl]-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride (1:1); 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-[(1S)-1,2-dihydroxyethyl]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S)-, hydrochloride (1:1). Grades: ≥90%. CAS No. 63950-05-0. Molecular formula: C27H31NO11.HCl. Mole weight: 582.00.
Doxorubicinol Hydrochloride (>90%)(Mixture of diastereomers)
Doxorubicinol Hydrochloride. (Mixture of diastereomers).
Doxorubicinol Hydrochloride(Mixture of diastereomers). Group: Biochemicals. Grades: Highly Purified. CAS No. 63950-05-0. Pack Sizes: 2mg. US Biological Life Sciences.
Worldwide
Doxorubicinolone (Mixture of Diastereomers)
Doxorubicinolone (Mixture of Diastereomers) is a metabolite of Epirubicin, which is an anthracycline topoisomerase inhibitor used as an antineoplastic agent. Synonyms: (8S,10S)-8-(1,2-Dihydroxyethyl)-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione; (8S,10S)-8-(1,2-Dihydroxyethyl)-6,8,10,11-tetrahydroxy-1-methoxy-7,8,9,10-tetrahydro-5,12-tetracenedione; 5,12-Naphthacenedione, 8-(1,2-dihydroxyethyl)-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-, (8S,10S)-. Grades: ≥95%. CAS No. 210837-88-0. Molecular formula: C21H20O9. Mole weight: 416.39.
Doxorubicinolone (Mixture of Diastereomers)
A metabolite of Epirubicin. Group: Biochemicals. Alternative Names: (8S,10S)-. Grades: Highly Purified. CAS No. 56149-23-6. Pack Sizes: 500ug. US Biological Life Sciences.