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| Product | Description | |
|---|---|---|
| Doripenem hydrate | 1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C15H24N4O6S2 · H2O. CAS No. 364622-82-2. Prepack ID 36359573-1g. Molecular Weight 438.52. See USA prepack pricing. |  |
| Doripenem Impurity 1 | Doripenem Impurity 1 is an impurity of Doripenem, a powerful antibiotic for the therapy of various bacterial infections. Synonyms: (4-nitrophenyl)methyl (5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-3-{[(3S,5S)-1-{[(4-nitrophenyl)methoxy]carbonyl}-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl}-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate. Grade: > 95%. CAS No. 491878-07-0. Molecular formula: C30H34N6O12S2. Mole weight: 734.77. |  |
| Doripenem Impurity 11 | Doripenem Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1233517-79-7. Molecular formula: C29H27N2O10P. Mole weight: 594.51. Catalog: APB1233517797. |  |
| Doripenem Impurity 5 (Methyl Acetoacetate) | Doripenem Impurity 5 (Methyl Acetoacetate). Uses: For analytical and research use. Group: Impurity standards. CAS No. 105-45-3. Molecular formula: C5H8O3. Mole weight: 116.12. Catalog: APB105453. | |
| Doripenem Impurity MAP-alfa isomer (Meropenem Related Compound 1) | Doripenem Impurity MAP-alfa isomer is a Meropenem intermediate. Synonyms: 4-Nitrobenzyl (4S,5R,6S)-3-[(diphenylphosphono)oxy]-6-[(R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate. Grade: > 95%. CAS No. 189188-38-3. Molecular formula: C29H27N2O10P. Mole weight: 594.51. | |
| Doripenem monohydrate | Doripenem (S 4661) monohydrate, a 1β-methyl parenteral carbapenem, has very broad-spectrum activity against Gram-positive and Gram-negative aerobic bacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S 4661 monohydrate. CAS No. 364622-82-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0187A. |  |
| Doripenem side-chain | Doripenem side-chain. Group: Biochemicals. Alternative Names: 4-Nitrobenzyl (2S, 4S) -4-acetylthio-2- [ [N-sulfamoyl-N- (tert-butoxycarbonyl) amino] methyl] pyrrolidine-1-carboxylate. Grades: Highly Purified. CAS No. 491878-06-9. Pack Sizes: 1g, 2g, 5g. US Biological Life Sciences. |  Worldwide |
| Dornase alfa | Dornase alfa (rhDNase) is a recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. Dornase alfa hydrolyzes the DNA present in sputum/mucus and reduces viscosity in the lungs, promoting improved clearance of secretions. Dornase alfa plays an important role in cystic fibrosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: rhDNase. CAS No. 143831-71-4. Pack Sizes: 500 μg. Product ID: HY-108858. | |
| D-Ornithine | D-Ornithine. Synonyms: (R)-ornithine. CAS No. 348-66-3. Molecular formula: C5H12N2O2. Mole weight: 132.16. | |
| D-ornithine 4,5-aminomutase | A pyridoxal-phosphate protein that requires a cobamide coenzyme for activity. Group: Enzymes. Synonyms: D-α-ornithine 5,4-aminomutase; D-ornithine aminomutase. Enzyme Commission Number: EC 5.4.3.5. CAS No. 62213-30-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5537; D-ornithine 4,5-aminomutase; EC 5.4.3.5; 62213-30-3; D-α-ornithine 5,4-aminomutase; D-ornithine aminomutase. Cat No: EXWM-5537. |  |
| D-Ornithine hydrochloride | D-Ornithine ((R)-Ornithine) hydrochloride is a constituent of bacterial cell wall. D-Ornithine hydrochloride promotes the production of L-arginine (HY-N0455). D-Ornithine hydrochloride enhances the expression of pyrrolysine-containing proteins [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-Ornithine hydrochloride. CAS No. 16682-12-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-34516. | |
| D-Ornithine hydrochloride | D-Ornithine hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: D(-)-2,5-DIAMINOPENTANOIC ACID HYDROCHLORIDE;D-2,5-DIAMINOPENTANOIC ACID HYDROCHLORIDE;D-ORNITHINE-OH HCL;D-ORTHININE MONOHYDROCHLORIDE;D(-)-ORNITHINE HYDROCHLORIDE;D-ORNITHINE HYDROCHLORIDE;D-ORNITHINE HCL;D-ORN, HCL. Product Category: Heterocyclic Organic Compound. CAS No. 99815-05-1. Molecular formula: C5H13ClN2O2. Mole weight: 168.62. Product ID: ACM99815051. Alfa Chemistry ISO 9001:2015 Certified. Categories: (R)-Ornithine hydrochloride. |  |
| D-Ornithine hydrochloride | D-Ornithine hydrochloride. Group: Biochemicals. Alternative Names: (R)-Ornithine hydrochloride; (R)-2,5-Diaminopentanoic acid hydrochloride; D-Ornithine monohydrochloride. Grades: Highly Purified. CAS No. 16682-12-5. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C5H13ClN2O2. US Biological Life Sciences. | Worldwide |
| D-Ornithine hydrochloride 99+% | D-Ornithine hydrochloride 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| D-Ornithine monohydrochloride | D-Ornithine monohydrochloride. Synonyms: D-Ornithine, hydrochloride (1:1); D-Ornithine, hydrochloride; Ornithine, monohydrochloride, D-; (2R)-2,5-Diaminopentanoic acid monohydrochloride; (R)-Ornithine hydrochloride; D-Orn-OH HCl; (R)-2,5-diaminopentanoic acid monohydrochloride. Grade: ≥95%. CAS No. 16682-12-5. Molecular formula: C5H12N2O2.HCl. Mole weight: 168.62. | |
| D-Ornithine,n2-[(1,1-dimethylethoxy)carbonyl]-n5-[imino[[(4-methylphenyl)sulfonyl]amino]methyl]-n2-methyl- | D-Ornithine,n2-[(1,1-dimethylethoxy)carbonyl]-n5-[imino[[(4-methylphenyl)sulfonyl]amino]methyl]-n2-methyl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Boc-D-Me-Arg(Tos)-OH, AKOS015909388, AK-88936, I14-32643, I14-34128, 136642-84-7. Product Category: Heterocyclic Organic Compound. CAS No. 136642-84-7. Molecular formula: C19H30N4O6S. Mole weight: 442.54. Purity: 0.96. IUPACName: (2R)-5-[[amino-[(4-methylphenyl)sulfonylamino]methylidene]amino]-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]pentanoic acid. Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(=NCCCC(C(=O)O)N(C)C(=O)OC(C)(C)C)N. Product ID: ACM136642847. Alfa Chemistry ISO 9001:2015 Certified. | |
| Dorrigocin A | It is produced by the strain of Streptomyces platensis subsp. rosaceus AB-1981F-75. It has weak anti-tumor cell activity and moderate anti-aspergillus and fusarium activity, but has no effect on yeast. Dorrigocin B has stronger antitumor and antifungal activities than Dorrigocin A. It can restore the morphology of RAS-deformed NIH/3T3 cells from the deformed phenotype to the normal phenotype. CAS No. 158446-29-8. Molecular formula: C27H41NO8. Mole weight: 507.61. | |
| Dorrigocin B | It is produced by the strain of Streptomyces platensis subsp. rosaceus AB-1981F-75. It has weak anti-tumor cell activity and moderate anti-aspergillus and fusarium activity, but has no effect on yeast. Dorrigocin B has stronger antitumor and antifungal activities than Dorrigocin A. It can restore the morphology of RAS-deformed NIH/3T3 cells from the deformed phenotype to the normal phenotype. CAS No. 158446-30-1. Molecular formula: C27H41NO8. Mole weight: 507.61. | |
| Dorsomorphin | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Dorsomorphin | Dorsomorphin (Compound C) is a selective and ATP-competitive AMPK inhibitor ( K i =109 nM in the absence of AMP). Dorsomorphin (BML-275) selectively inhibits BMP type I receptors ALK2 , ALK3 , and ALK6. Dorsomorphin can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Compound C; BML-275. CAS No. 866405-64-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13418A. | |
| Dorsomorphin | Dorsomorphin is a potent and selective inhibitor of AMPK (AMP-activated protein kinase) (Ki = 109 nM), induced by AICAR and metformin. It also inhibits bone morphogenetic protein (BMP) receptors including BMPR-IA (ALK3) and BMPR-IB (ALK6). Dorsomorphin can induce myocardial differentiation in mouse embryonic stem cells (mESCs). Uses: Protein kinase inhibitors. Synonyms: 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine; Compound C; AMPK Inhibitor, Compound C; BML-275. Grade: >98%. CAS No. 866405-64-3. Molecular formula: C24H25N5O. Mole weight: 399.49. | |
| Dorsomorphin | Dorsomorphin Inhibitor. Uses: Scientific use. Product Category: T1977. CAS No. 866405-64-3. |  |
| Dorsomorphin | Dorsomorphin. Group: Biochemicals. Alternative Names: Compound C, AMPK Inhibitor, BML-275, 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine. Grades: Highly Purified. CAS No. 866405-64-3. Pack Sizes: 10mg, 50mg. Molecular Formula: C24 H25 N5, Molecular Weight: 399.5. US Biological Life Sciences. | Worldwide |
| Dorsomorphin 2HCl | Dorsomorphin (hydrochloride) is a potent, reversible inhibitor of AMP kinase (AMPK; Ki = 109 nM) that does not exhibit significant activity on structurally related kinases, including ZAPK, SYK, PKCθ, PKA, and JAK3. CAS No. 1219168-18-9. Molecular formula: C24H25N5O.2HCl. Mole weight: 472.414. | |
| Dorsomorphin dihydrochloride | Dorsomorphin (Compound C) dihydrochloride is a potent, selective and ATP-competitive AMPK inhibitor, with a K i of 109 nM. Dorsomorphin dihydrochloride inhibits BMP pathway by targeting the type I receptors ALK2 , ALK3 , and ALK6. Dorsomorphin dihydrochloride can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Compound C dihydrochloride; BML-275 dihydrochloride. CAS No. 1219168-18-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13418. | |
| Dorzagliatin | Dorzagliatin is a dual-acting glucokinase (GK) activator that improves glycaemic control and pancreatic β-cell function in patients with type 2 diabetes. Synonyms: HMS-5552; RO-5305552; Sinogliatin. CAS No. 1191995-00-2. Molecular formula: C22H27ClN4O5. Mole weight: 462.93. | |
| Dorzagliatin | Dorzagliatin (HMS5552), a dual-acting glucokinase (GK) activator, improves glycaemic control and pancreatic β-cell function in type 2 diabetes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HMS5552. CAS No. 1191995-00-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109030. | |
| Dorzolamide | Carbonic anhydrase inhibitor. Antiglaucoma agent. Group: Biochemicals. Alternative Names: (4S,6S)-. Grades: Highly Purified. CAS No. 130693-82-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Dorzolamide | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Dorzolamide-[d5] | Dorzolamide-[d5] is the labelled analogue of Dorzolamide. Dorzolamide is a carbonic anhydrase inhibitor used to lower the pressure of eyes with glaucoma. Synonyms: Dorzolamide D5; (4S,6S)-4-[(2H5)Ethylamino]-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide. Grade: 95% by HPLC; 95% atom D. CAS No. 1227097-70-2. Molecular formula: C10H11D5N2O4S3. Mole weight: 329.47. | |
| Dorzolamide-d5 hydrochloride | Dorzolamide-d5 is used as an internal standard for the quantification of dorzolamide by GC- or LC-MS. Dorzolamide is an inhibitor of carbonic anhydrase (CA), including CAII, CAV, CAVI, CAIX, CAXII, CAXIII, and CAXIV. Synonyms: L-671,152-d5; MK-507-d5; Trusopt-d5; (4S,6S)-4-((ethyl-d5)amino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide, monohydrochloride. Grade: ≥99% atom D. Molecular formula: C10H11D5N2O4S3·HCl. Mole weight: 365.93. | |
| Dorzolamide EP Impurity A (Hydrochloride) | Dorzolamide EP Impurity A (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4R,6R)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride. CAS No. 122028-36-8. Molecular formula: C10H17ClN2O4S3. Mole weight: 360.90. Catalog: APB122028368. | |
| Dorzolamide HCl | Dorzolamide HCl. Group: Biochemicals. Grades: Highly Purified. CAS No. 130693-82-2. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C10H16N2O4S3·ClH. US Biological Life Sciences. | Worldwide |
| Dorzolamide HCL USP | Dorzolamide HCL USP. |  CA, FL & NJ |
| Dorzolamide hydrochloride | Dorzolamide (L671152) hydrochloride is a potent carbonic anhydrase II inhibitor, with IC 50 values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. Dorzolamide possesses anti-tumor activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: L671152 hydrochloride; MK507 hydrochloride. CAS No. 130693-82-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 100 mg; 250 mg. Product ID: HY-B0109A. | |
| Dorzolamide Hydrochloride | Dorzolamide hydrochloride is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent and topically applied in the form of eye drops. Dorzolamide hydrochloride is used to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension. Synonyms: Dorzolamide HCl; TRUSOPT; (2S,4S)-2-Ethylamino-4-methyl-5,5-dioxo-5,7-dithiabicyclo[4.3.0]nona-8,10-diene-8-sulfonamide hydrochloride; (4S-trans)-4-(ethylamino)-5,6-dihydro-6-methyl4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide monohydrochloride. Grade: >98%. CAS No. 130693-82-2. Molecular formula: C10H17ClN2O4S3. Mole weight: 360.886. | |
| Dorzolamide Impurity A | Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonic anhydrase II in vitro. It has been found to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension. Uses: Carbonic anhydrase inhibitors. Synonyms: L671152; MK507; L 671152; MK 507; L-671152; MK-507; Trusopt. Grade: >98%. CAS No. 120279-96-1. Molecular formula: C10H16N2O4S3. Mole weight: 324.44. | |
| Dorzolamide Impurity B | Dorzolamide Impurity. Synonyms: (4R,6S)-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-Dioxide; (4R-cis)-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-Dioxide. Grade: > 95%. CAS No. 149249-72-9. Molecular formula: C10H16N2O4S3. Mole weight: 324.44. | |
| Dorzolamide Impurity D HCl (N-Desethyl Dorzolamide HCl) | N-Deethyl Dorzolamide Hydrochloride is a metabolite of Dorzolamide. Synonyms: (4S-trans)-4-amino-5,6-dihydro-6-methyl-4H-Thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide Monohydrochloride. Grade: > 95%. CAS No. 164455-27-0. Molecular formula: C8H12N2O4S3·HCl. Mole weight: 332.85. | |
| Dorzolamide Maleic Acid Adduct | Dorzolamide Maleic Acid Adduct. Group: Biochemicals. Alternative Names: 2-(Ethyl((4S,6S)-6-methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)amino)succinic Acid. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C14H20N2O8S3, Molecular Weight: 440.51. US Biological Life Sciences. | Worldwide |
| Dorzolamide Maleic Acid Adduct | An impurity of Dorzolamide. Dorzolamide is a carbonic anhydrase inhibitor primarily used to lower intraocular pressure in conditions such as glaucoma and ocular hypertension. Synonyms: N-Ethyl-N-((4S,6S)-6-methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)aspartic acid; 2-(Ethyl((4S,6S)-6-methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)amino)succinic Acid; Dorzolamide Maleic Acid. Grade: ≥95%. Molecular formula: C14H20N2O8S3. Mole weight: 440.51. | |
| Dosimertinib mesylate | Dosimertinib-d 5 (mesylate) is a potent and orally active EGFR inhibitor. Dosimertinib-d 5 (mesylate) decreases the expression of p-EGFR and p-ERK protein levels. Dosimertinib-d 5 (mesylate) shows antiproliferative and anti-tumor activity. Dosimertinib-d 5 (mesylate) has the potential for the research of non-small-cell lung cancer (NSCLC)[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 2403760-72-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-142283AS. | |
| DOSPA | DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 282533-23-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-142997. | |
| Dostarlimab | Dostarlimab (TSR-042) is a humanized anti- PD-1 monoclonal antibody. Dostarlimab binds with high affinity to human PD-1 and competitively inhibits its interaction with its ligands, PD-L1 and PD-L2, with IC 50 s of 1.8 and 1.5 nM, respectively [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TSR-042. CAS No. 2022215-59-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99345. | |
| Dosulepin | Dosulepin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3E)-3-Dibenzo[b,E]thiepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine;11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo(b,e)thiepin;1-Propanamine, 3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-;3-Dibenzo(b,e)thiepin-11(6H)-ylidene-N,N-dimethyl-1-pro. Product Category: Heterocyclic Organic Compound. Appearance: Pale Yellow Low Melting Solid. CAS No. 113-53-1. Molecular formula: C19H21NS. Mole weight: 295.4416. Density: 1.148 g/cm³. Product ID: ACM113531. Alfa Chemistry ISO 9001:2015 Certified. | |
| Dosulepin HCl | Dosulepin HCl is a pharmacological agent used in studying a diverse array of mental conditions such as depression and anxiety. Grade: > 95%. CAS No. 897-15-4. Molecular formula: C19H21NS·HCl. Mole weight: 331.909. | |
| Dosulepin hydrochloride | Dosulepin hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DOTHIEPIN HCL;DOTHIEPIN HYDROCHLORIDE;DOSULEPIN HCL;11-(3-dimethylaminopropylidene)-6,11-dihydrodibenzo(b,e)thiepinehydrochlorid;3-dibenzo(b,e)thiepin-11(6h)-ylidene-n,n-dimethyl-1-propanaminhydrochlor;dosulepinchloride;dosulepinhydrochloride;n,n-dimethy. Product Category: Heterocyclic Organic Compound. CAS No. 897-15-4. Molecular formula: C19H21NS. Mole weight: 295.44. Product ID: ACM897154. Alfa Chemistry ISO 9001:2015 Certified. | |
| Dosulepin Impurity A | Dothiepin impurity. Grade: > 95%. CAS No. 1447-71-8. Molecular formula: C19H21NOS. Mole weight: 311.45. | |
| Dosulepin Impurity C | Dothiepin intermediate. Synonyms: 11-[3-(Dimethylamino)propyl]-6,11-dihydro-dibenzo[b,e]thiepin-11-ol; 6,11-Dihydro-11-hydroxy Dothiepin. Grade: > 95%. CAS No. 1531-85-7. Molecular formula: C19H23NOS. Mole weight: 313.47. | |
| Dosulepin Impurity E | Dothiepin impurity. Synonyms: (E)-3-(5,5-Dioxidodibenzo[b,e]thiepin-11(6H)-ylidene)-N,N-dimethyl-1-propanamine; (E)-3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine S,S-Dioxide; (E)-11-(3-(Dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]thiepine 5,5-Dioxide. Grade: > 95%. CAS No. 25846-81-5. Molecular formula: C19H21NO2S. Mole weight: 327.44. | |
| Dosulepin Sulfone | Dosulepin Sulfone is a pharmacological agent employed within the research of the symptoms associated with melancholic states and sundry afflictions of emotional disposition. Synonyms: 33301-24-5; 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo(b,e)thiepine-5,5-dioxide(3E)-3-(5,5-dioxo-6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethylpropan-1-amineDibenzo(b,e)thiepin-delta(sup 11(6H)),gamma-propylamine, N,N-dimethyl-, 5,5-dioxide; ZINC346580. Grade: > 95%. CAS No. 33301-24-5. Molecular formula: C19H21NO2S. Mole weight: 327.45. | |
| Dot | Dot - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Dot1L human | recombinant, expressed in E. coli, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Dot1L-IN-1 | Dot1L-IN-1 is a selective and highly potent Dot1L inhibitor with a Ki of 2 pM. Synonyms: N2-{[2-Chloro-3-(2-methyl-3-pyridinyl)-1-benzothiophen-5-yl]carbamoyl}-N-(3-{methyl[(3R)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-piperidinyl]amino}propyl)glycinamide; Acetamide, 2-[[[[2-chloro-3-(2-methyl-3-pyridinyl)benzo[b]thien-5-yl]amino]carbonyl]amino]-N-[3-[methyl[(3R)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-piperidinyl]amino]propyl]-. Grade: ≥95%. CAS No. 2088518-50-5. Molecular formula: C32H36ClN9O2S. Mole weight: 646.21. | |
| Dot1L-IN-2 | Dot1L-IN-2 is a potent, selective and orally bioavailable Dot1L (a histone methyltransferase) inhibitor, with an IC50 and Ki of 0.4 nM and 0.08 nM, respectively. Synonyms: 2,4-Pyrimidinediamine, N4-methyl-N2-[2-methyl-1-[2-[(3-methyl-3H-imidazo[4,5-b]pyridin-6-yl)oxy]phenyl]-1H-indol-6-yl]-; N4-Methyl-N2-(2-methyl-1-{2-[(3-methyl-3H-imidazo[4,5-b]pyridin-6-yl)oxy]phenyl}-1H-indol-6-yl)-2,4-pyrimidinediamine. Grade: ≥95%. CAS No. 1940206-71-2. Molecular formula: C27H24N8O. Mole weight: 476.53. | |
| Dot1L-IN-4 | Dot1L-IN-4 is a potent disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor with an IC50 SPA DOT1L of 0.11 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2565705-02-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135127. | |
| Dot1L-IN-4 | Dot1L-IN-4 is a potent inhibitor of telomeric silencing 1-like protein (DOT1L) with an IC50 SPA DOT1L of 0.11 nM. Synonyms: 1,2-Benzenediamine, N1-[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]-N2-[4-methoxy-6-(1-piperazinyl)-1,3,5-triazin-2-yl]-4-(methylsulfonyl)-; N1-[(S)-(3-Chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]-N2-[4-methoxy-6-(1-piperazinyl)-1,3,5-triazin-2-yl]-4-(methylsulfonyl)-1,2-benzenediamine. Grade: ≥95%. CAS No. 2565705-02-2. Molecular formula: C28H27ClF2N8O5S. Mole weight: 661.08. | |
| Dot1L-IN-5 | Dot1L-IN-5 is a potent inhibitor of telomeric silencing 1-like protein (DOT1L) with an IC50 SPA DOT1L of 0.17 nM. Synonyms: Benzenesulfonamide, 3-[(4-amino-6-methoxy-1,3,5-triazin-2-yl)amino]-4-[[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]amino]-; 3-[(4-Amino-6-methoxy-1,3,5-triazin-2-yl)amino]-4-{[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]amino}benzenesulfonamide. CAS No. 2565705-03-3. Molecular formula: C23H19ClF2N8O5S. Mole weight: 592.96. | |
| Dot1L-IN-6 | Dot1L-IN-6 is a potent inhibitor of telomeric silencing 1-like protein (DOT1L) with an IC50 SPA DOT1L of 0.19 nM. Synonyms: 1,2-Benzenediamine, N1-[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]-N2-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-(methylsulfonyl)-; N1-[(S)-(3-Chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]-N2-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-(methylsulfonyl)-1,2-benzenediamine. CAS No. 2565705-01-1. Molecular formula: C25H21ClF2N6O6S. Mole weight: 606.99. | |
| DOTA | Bifunctional DOTA aconjugates to peptides and has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and therapeutic radiopharmaceuticals. Group: Biochemicals. Alternative Names: 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid; 1,4,7,10-Tetra(carboxymethyl)-1,4,7,10-tetraazacyclododecane; 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid; DOTA; NSC 681107; Tetraxetan. Grades: Highly Purified. CAS No. 60239-18-1. Pack Sizes: 100mg, 250mg, 500mg. US Biological Life Sciences. | Worldwide |
| DOTA(allyl ester)3 | DOTA(allyl ester)3, a protected DOTA derivative, is used for coupling to acid- or base-sensitive compounds. Synonyms: DOTA(OAll)3; 4,7,10-Tri-(allyloxycarbonylmethyl)-1,4,7,10-tetraazacyclododecan-1-yl-acetic acid; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid 1,4,7-triallyl ester; 2-(4,7,10-tris(2-(allyloxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid; {4,7,10-Tris[2-(allyloxy)-2-oxoethyl]-1,4,7,10-tetraazacyclododecan-1-yl}acetic acid. Molecular formula: C25H40N4O8. Mole weight: 524.61. | |
| DOTA-Biotin-Sarcosine | DOTA-Biotin-Sarcosine. Synonyms: [3aS-[3aα,4β(R*),6aα]]-2-[[4-[[[[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]methylamino]acetyl]amino]phenyl]methyl]-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid. CAS No. 180978-54-5. Molecular formula: C36H54N8O11S. Mole weight: 806.93. | |
| DOTA derivative | DOTA derivative is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride. Synonyms: DOTA derivative. Grade: >98%. CAS No. 153777-70-9. Molecular formula: C43H50N4O8S4. Mole weight: 879.14. | |
| DOTA-Lanreotide | An impurity of Lanreotide. Lanreotide is a synthetic somatostatin analogue used primarily to treat conditions related to excessive hormone production, such as acromegaly and neuroendocrine tumors. Synonyms: L-Threoninamide, 3-(2-naphthalenyl)-N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2→7)-disulfide; DOTA-BIM 23014; DOTA-LAN; DOTA-D-2Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys7); DOTA-3-(2-naphthyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide (2->7)-disulfide. Grade: ≥95%. CAS No. 213187-44-1. Molecular formula: C70H95N15O17S2. Mole weight: 1482.73. | |
| DOTA-LM3 | DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. DOTA-LM3 can be labeled with 177Lu and 68Ga for imaging and detecting tumors. Synonyms: DOTA-Cpa-(D-Cys)-Tyr-[D-Aph(Cbm)]-Lys-Thr-Cys-(D-Tyr)-NH2 [Disulfide Bond (D-Cys)2/Cys7]; DOTA-Cpa-D-Cys-Tyr-D-Aph(Cbm)-Lys-Thr-Cys-D-Tyr-NH2 [Disulfide Bond (D-Cys)2/Cys7]. CAS No. 1192362-32-5. Molecular formula: C69H93ClN16O19S2. Mole weight: 1550.16. | |
| DOTA-LM3 | DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis[1][2]. DOTA-LM3 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 1192362-32-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5126. | |
| DOTA-NHS-ester | DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for the detection of tumors[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 170908-81-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-128890. DOTA-?NHS-ester | |
| DOTA-NOC | DOTA-NOC is a potent chelating agent extensively used in radiopharmaceuticals for the targeted imaging and therapy of neuroendocrine tumors. By combining with diverse radiometals, such as lutetium-177 or yttrium-90, it generates therapeutic agents that specifically bind to neuroendocrine tumor cells. The DOTA-NOC derivatives have displayed remarkable specificity and affinity for somatostatin receptors, endowing it with a unique potential for cancer therapy. Its diverse applications stem from its impressive properties, which include high burstiness in sentence structure and an elevated level of perplexity in its descriptions. Synonyms: L-Cysteinamide, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; DOTA-[Nal3]-octreotide; H-D-Phe(DOTA)-Cys(1)-Nal-D-Trp-Lys-Thr-Cys(1)-Thr-ol; DOTA-D-Phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol (2->7)-disulfide. Grade: 95%. CAS No. 619300-53-7. Molecular formula: C69H94N14O17S2. Mole weight: 1455.70. | |
| DOTAP chloride | ?98% (TLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| DOTAP chloride | DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 1,2-Dioleoyl-3-trimethylammonium-propane chloride. CAS No. 132172-61-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-112754A. | |
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