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| Product | Description | |
|---|---|---|
| Dorzolamide Maleic Acid Adduct | Dorzolamide Maleic Acid Adduct. Group: Biochemicals. Alternative Names: 2-(Ethyl((4S,6S)-6-methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)amino)succinic Acid. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C14H20N2O8S3, Molecular Weight: 440.51. US Biological Life Sciences. |  Worldwide |
| Dosimertinib-d5 mesylate | Dosimertinib-d5 (mesylate) is a potent and orally active EGFR inhibitor. Dosimertinib-d5 (mesylate) decreases the expression of p-EGFR and p-ERK protein levels. Dosimertinib-d5 (mesylate) shows antiproliferative and anti-tumor activity. Dosimertinib-d5 (mesylate) has the potential for the research of non-small-cell lung cancer (NSCLC)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD-9291-d5 mesylate; Mereletinib-d5 mesylate. CAS No. 2403760-72-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-142283AS. |  |
| Dostarlimab | Dostarlimab (TSR-042) is a humanized anti-PD-1 monoclonal antibody. Dostarlimab binds with high affinity to human PD-1 and competitively inhibits its interaction with its ligands, PD-L1 and PD-L2, with IC50s of 1.8 and 1.5 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TSR-042; ANB-011; WBP-285. CAS No. 2022215-59-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P99345. | |
| Dosulepin HCl | Dosulepin HCl is a pharmacological agent used in studying a diverse array of mental conditions such as depression and anxiety. Grade: > 95%. CAS No. 897-15-4. Molecular formula: C19H21NS·HCl. Mole weight: 331.909. |  |
| Dosulepin Impurity A | Dothiepin impurity. Grade: > 95%. CAS No. 1447-71-8. Molecular formula: C19H21NOS. Mole weight: 311.45. | |
| Dosulepin Impurity C | Dothiepin intermediate. Synonyms: 11-[3-(Dimethylamino)propyl]-6,11-dihydro-dibenzo[b,e]thiepin-11-ol; 6,11-Dihydro-11-hydroxy Dothiepin. Grade: > 95%. CAS No. 1531-85-7. Molecular formula: C19H23NOS. Mole weight: 313.47. | |
| Dosulepin Impurity E | Dothiepin impurity. Synonyms: (E)-3-(5,5-Dioxidodibenzo[b,e]thiepin-11(6H)-ylidene)-N,N-dimethyl-1-propanamine; (E)-3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine S,S-Dioxide; (E)-11-(3-(Dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]thiepine 5,5-Dioxide. Grade: > 95%. CAS No. 25846-81-5. Molecular formula: C19H21NO2S. Mole weight: 327.44. | |
| Dosulepin Sulfone | Dosulepin Sulfone is a pharmacological agent employed within the research of the symptoms associated with melancholic states and sundry afflictions of emotional disposition. Synonyms: 33301-24-5; 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo(b,e)thiepine-5,5-dioxide(3E)-3-(5,5-dioxo-6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethylpropan-1-amineDibenzo(b,e)thiepin-delta(sup 11(6H)),gamma-propylamine, N,N-dimethyl-, 5,5-dioxide; ZINC346580. Grade: > 95%. CAS No. 33301-24-5. Molecular formula: C19H21NO2S. Mole weight: 327.45. | |
| Dot | Dot - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Dot1L-IN-1 | Dot1L-IN-1 is a selective and highly potent Dot1L inhibitor with a Ki of 2 pM. Synonyms: N2-{[2-Chloro-3-(2-methyl-3-pyridinyl)-1-benzothiophen-5-yl]carbamoyl}-N-(3-{methyl[(3R)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-piperidinyl]amino}propyl)glycinamide; Acetamide, 2-[[[[2-chloro-3-(2-methyl-3-pyridinyl)benzo[b]thien-5-yl]amino]carbonyl]amino]-N-[3-[methyl[(3R)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-piperidinyl]amino]propyl]-. Grade: ≥95%. CAS No. 2088518-50-5. Molecular formula: C32H36ClN9O2S. Mole weight: 646.21. | |
| Dot1L-IN-2 | Dot1L-IN-2 is a potent, selective and orally bioavailable Dot1L (a histone methyltransferase) inhibitor, with an IC50 and Ki of 0.4 nM and 0.08 nM, respectively. Synonyms: 2,4-Pyrimidinediamine, N4-methyl-N2-[2-methyl-1-[2-[(3-methyl-3H-imidazo[4,5-b]pyridin-6-yl)oxy]phenyl]-1H-indol-6-yl]-; N4-Methyl-N2-(2-methyl-1-{2-[(3-methyl-3H-imidazo[4,5-b]pyridin-6-yl)oxy]phenyl}-1H-indol-6-yl)-2,4-pyrimidinediamine. Grade: ≥95%. CAS No. 1940206-71-2. Molecular formula: C27H24N8O. Mole weight: 476.53. | |
| Dot1L-IN-4 | Dot1L-IN-4 is a potent inhibitor of telomeric silencing 1-like protein (DOT1L) with an IC50 SPA DOT1L of 0.11 nM. Synonyms: 1,2-Benzenediamine, N1-[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]-N2-[4-methoxy-6-(1-piperazinyl)-1,3,5-triazin-2-yl]-4-(methylsulfonyl)-; N1-[(S)-(3-Chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]-N2-[4-methoxy-6-(1-piperazinyl)-1,3,5-triazin-2-yl]-4-(methylsulfonyl)-1,2-benzenediamine. Grade: ≥95%. CAS No. 2565705-02-2. Molecular formula: C28H27ClF2N8O5S. Mole weight: 661.08. | |
| Dot1L-IN-5 | Dot1L-IN-5 is a potent inhibitor of telomeric silencing 1-like protein (DOT1L) with an IC50 SPA DOT1L of 0.17 nM. Synonyms: Benzenesulfonamide, 3-[(4-amino-6-methoxy-1,3,5-triazin-2-yl)amino]-4-[[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]amino]-; 3-[(4-Amino-6-methoxy-1,3,5-triazin-2-yl)amino]-4-{[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]amino}benzenesulfonamide. CAS No. 2565705-03-3. Molecular formula: C23H19ClF2N8O5S. Mole weight: 592.96. | |
| Dot1L-IN-5 | Dot1L-IN-5 is a potent disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor with an IC50 of 0.17 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2565705-03-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135128. | |
| Dot1L-IN-6 | Dot1L-IN-6 is a potent inhibitor of telomeric silencing 1-like protein (DOT1L) with an IC50 SPA DOT1L of 0.19 nM. Synonyms: 1,2-Benzenediamine, N1-[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]-N2-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-(methylsulfonyl)-; N1-[(S)-(3-Chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]-N2-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-(methylsulfonyl)-1,2-benzenediamine. CAS No. 2565705-01-1. Molecular formula: C25H21ClF2N6O6S. Mole weight: 606.99. | |
| DOTA | Bifunctional DOTA aconjugates to peptides and has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and therapeutic radiopharmaceuticals. Group: Biochemicals. Alternative Names: 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid; 1,4,7,10-Tetra(carboxymethyl)-1,4,7,10-tetraazacyclododecane; 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid; DOTA; NSC 681107; Tetraxetan. Grades: Highly Purified. CAS No. 60239-18-1. Pack Sizes: 100mg, 250mg, 500mg. US Biological Life Sciences. | Worldwide |
| DOTA(allyl ester)3 | DOTA(allyl ester)3, a protected DOTA derivative, is used for coupling to acid- or base-sensitive compounds. Synonyms: DOTA(OAll)3; 4,7,10-Tri-(allyloxycarbonylmethyl)-1,4,7,10-tetraazacyclododecan-1-yl-acetic acid; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid 1,4,7-triallyl ester; 2-(4,7,10-tris(2-(allyloxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid; {4,7,10-Tris[2-(allyloxy)-2-oxoethyl]-1,4,7,10-tetraazacyclododecan-1-yl}acetic acid. Molecular formula: C25H40N4O8. Mole weight: 524.61. | |
| DOTA-benzene | DOTA-benzene. CAS No. 123317-52-2. Purity: ≥98%. Product ID: ACM123317522. Molecular formula: C23H35N5O8. Mole weight: 509.55. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| DOTA-Biotin-Sarcosine | DOTA-Biotin-Sarcosine. Synonyms: [3aS-[3aα,4β(R*),6aα]]-2-[[4-[[[[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]methylamino]acetyl]amino]phenyl]methyl]-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid. CAS No. 180978-54-5. Molecular formula: C36H54N8O11S. Mole weight: 806.93. | |
| DOTA derivative | DOTA derivative is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride. Synonyms: DOTA derivative. Grade: >98%. CAS No. 153777-70-9. Molecular formula: C43H50N4O8S4. Mole weight: 879.14. | |
| DOTA-ECL1i | DOTA-ECL1i is a conjugate of the CCR2 inhibitor ECL1i (HY-P11553) and DOTA. When radiolabeled with 68Ga, DOTA-ECL1i serves as a PET tracer that targets CCR2 expression. DOTA-ECL1i can be used in research related to pulmonary fibrosis, cardiac injury, abdominal aortic aneurysm inflammation, atherosclerosis, head and neck cancer, and pancreatic cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2850189-48-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P11553B. | |
| DOTAGA-anhydride | DOTAGA-anhydride is a DOTA-based metal chelator that can bind to radionuclides and is used to prepare radionuclide drug conjugates (RDCs). DOTAGA-anhydride has been successfully used for labeling antibodies (e.g., Trastuzumab (HY-P9907)). DOTAGA-anhydride can be used for the synthesis of a bimodal tag for Single-photon emission computed tomography (SPECT) or PET/optical imaging[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1375475-53-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W087187. | |
| DOTAGA-FAP-2286-ALB | DOTAGA-FAP-2286-ALB is a derivative of Rofapitide tetraxetan (HY-147057). DOTAGA-FAP-2286-ALB is a selective fibroblast activation protein (FAP) inhibitor with an IC50 value of 67.5 nM. DOTAGA-FAP-2286-ALB enhances tumor retention via albumin interaction, prolonging blood circulation and improving radiometal complex stability (e.g., with 111In and 225Ac). DOTAGA-FAP-2286-ALB is promising for research of radionuclide therapy (TRT) of FAP-positive solid tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3114056-16-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-173374. | |
| DOTA-GA-maleimide | DOTA-GA-maleimide is a bifunctional chelator with protein conjugation and radiometal chelation capabilities. DOTA-GA-maleimide forms stable complexes with 111In and conjugates with proteins via maleimide chemistry. DOTA-GA-maleimide conjugates with LFn, enabling 111In radiolabeling of LFn through direct or pre-labeling strategies. Radiolabeled LFn is applicable to MMP activity imaging studies. DOTA-GA-maleimide is used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1800229-46-2. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157977. | |
| DOTA-GPC3 targeting peptide 2 | DOTA-GPC3 targeting peptide 2 (Sequence 30) is a RDC peptide targeting GPC3, with Kd of 0.3 nM. DOTA-GPC3 targeting peptide 2 is composed of DOTA and GPC3 targeting peptide 2. DOTA-GPC3 targeting peptide 2 can be labeled with radioactive elements[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3066439-94-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W1124925. | |
| DOTA-JR11 | DOTA-JR11 is a somatostatin receptor 2 (SSTR2) antagonist. DOTA-JR11 can be labeled by 68Ga, used for paired imaging in neuroendocrine tumors (NETs) research[1]. DOTA-JR11 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Satoreotide tetraxetan. CAS No. 1039726-31-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5128. | |
| DOTA-Lanreotide | An impurity of Lanreotide. Lanreotide is a synthetic somatostatin analogue used primarily to treat conditions related to excessive hormone production, such as acromegaly and neuroendocrine tumors. Synonyms: L-Threoninamide, 3-(2-naphthalenyl)-N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2→7)-disulfide; DOTA-BIM 23014; DOTA-LAN; DOTA-D-2Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys7); DOTA-3-(2-naphthyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide (2->7)-disulfide. Grade: ≥95%. CAS No. 213187-44-1. Molecular formula: C70H95N15O17S2. Mole weight: 1482.73. | |
| DOTA-LM3 | DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis[1][2]. DOTA-LM3 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Category: Signaling pathways. CAS No. 1192362-32-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5126. | |
| DOTA-LM3 | DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. DOTA-LM3 can be labeled with 177Lu and 68Ga for imaging and detecting tumors. Synonyms: DOTA-Cpa-(D-Cys)-Tyr-[D-Aph(Cbm)]-Lys-Thr-Cys-(D-Tyr)-NH2 [Disulfide Bond (D-Cys)2/Cys7]; DOTA-Cpa-D-Cys-Tyr-D-Aph(Cbm)-Lys-Thr-Cys-D-Tyr-NH2 [Disulfide Bond (D-Cys)2/Cys7]. CAS No. 1192362-32-5. Molecular formula: C69H93ClN16O19S2. Mole weight: 1550.16. | |
| DOTAM-mono-acid | DOTAM-mono-acid is a chelator with DOTAM as its core. DOTAM-mono-acid contains a carboxylic acid group that can be activated to form an amide bond with the N-terminus of a peptide. DOTAM-mono-acid can form peptide conjugates for radiometal labeling[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 913528-04-8. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg. Product ID: HY-W717743. | |
| DOTAMTATE | DOTAMTATE is a somatostatin analogue. DOTAMTATE marked 212Pb is promising for research of somatostatin receptor positive neuroendocrine tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2415661-92-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P10920. | |
| DOTA-?NHS-ester | DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for the detection of tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 170908-81-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-128890. | |
| DOTA-NHS-ester | DOTA-NHS-ester. Alternative Names: 2,2',2''-(10-(2-((2,5-Dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid. CAS No. 170908-81-3. Purity: 98%. Product ID: ACM170908813-1. Molecular formula: C20H31N5O10. Mole weight: 501.49. Alfa Chemistry - ISO 9001:32057 Certified. | |
| DOTA-NHS-ester hexafluorophosphate TFA | DOTA-NHS-ester hexafluorophosphate TFA. CAS No. 1823122-52-6. Purity: ≥95%. Product ID: ACM1823122526. Molecular formula: C20H31N5O10·C2HF3O2·HPF6. Mole weight: 761.48. Alfa Chemistry - ISO 9001:32057 Certified. | |
| DOTA-NOC | DOTA-NOC (DOTA-Nal3-octreotide) is a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5. DOTA-NOC can be used for labeling with various radiometals, and development of radiopeptide imaging[1]. DOTA-NOC can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: DOTA-Nal3-octreotide. CAS No. 619300-53-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2112. | |
| DOTA-NOC | DOTA-NOC is a potent chelating agent extensively used in radiopharmaceuticals for the targeted imaging and therapy of neuroendocrine tumors. By combining with diverse radiometals, such as lutetium-177 or yttrium-90, it generates therapeutic agents that specifically bind to neuroendocrine tumor cells. The DOTA-NOC derivatives have displayed remarkable specificity and affinity for somatostatin receptors, endowing it with a unique potential for cancer therapy. Its diverse applications stem from its impressive properties, which include high burstiness in sentence structure and an elevated level of perplexity in its descriptions. Synonyms: L-Cysteinamide, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; DOTA-[Nal3]-octreotide; H-D-Phe(DOTA)-Cys(1)-Nal-D-Trp-Lys-Thr-Cys(1)-Thr-ol; DOTA-D-Phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol (2->7)-disulfide. Grade: 95%. CAS No. 619300-53-7. Molecular formula: C69H94N14O17S2. Mole weight: 1455.70. | |
| DOTAP chloride | DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,2-Dioleoyl-3-trimethylammonium-propane chloride. CAS No. 132172-61-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg. Product ID: HY-112754A. | |
| DOTAP chloride (GMP Like) | DOTAP chloride (GMP Like) is the GMP Like class DOTAP chloride (HY-112754A). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOTAP chloride is a cationic lipid with good membrane fusion ability and biocompatibility. DOTAP chloride (GMP Like) can be used as an excipient for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) without the use of helper lipid[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,2-Dioleoyl-3-trimethylammonium-propane chloride (GMP Like). CAS No. 132172-61-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-112754AGL. | |
| DOTA-PEG5-azide | DOTA-PEG5-azide is a polyethylene glycol (PEG)-based PROTAC linker. DOTA-PEG5-azide can be used in the synthesis of a series of PROTACs. Synonyms: DOTA-PEG5-C2-azide. Grade: 95%. Molecular formula: C28H52N8O12. Mole weight: 692.76. | |
| DOTA-PEG5-azide | DOTA-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DOTA-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 3104986-47-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140752. | |
| DOTAP mesylate | DOTAP mesylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 252769-92-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W127426. | |
| DOTAP methylsulfate | DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design | |
| Dotarizine | Dotarizine. Group: Biochemicals. Alternative Names: 1-(Diphenylmethyl)-4-[3-(2-phenyl-1,3-dioxolan-2-yl)propyl]piperazine; FI-6026. Grades: Highly Purified. CAS No. 84625-59-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C29H34N2O2. US Biological Life Sciences. | Worldwide |
| DOTATATE | DOTATATE is a radiolabeled somatostatin analog used in medical imaging and therapy for neuroendocrine tumors (NETs). DOTATATE is a peptide derivative that binds selectively to somatostatin receptors (mainly subtype 2), which are overexpressed on the surface of neuroendocrine tumor cells. This allows for specific targeting of these tumors. Synonyms: L-Threonine, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide; L-Threonine, N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide; DOTA-octreotate; DOTA-TATE; DOTA-[Tyr3]-Octreotide Acid; DOTA-(Tyr3)-octreotate. Grade: ≥95%. CAS No. 177943-88-3. Molecular formula: C65H90N14O19S2. Mole weight: 1435.63. | |
| DOTATATE | DOTATATE is a DOTA-conjugated peptide. DOTATATE can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT)[1][2][3][4]. DOTATATE can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Oxodotreotide. CAS No. 177943-88-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-106244. | |
| DOTATATE acetate | DOTATATE acetate is a radiolabeled somatostatin analog used in medical imaging and therapy for neuroendocrine tumors (NETs). DOTATATE acetate is a peptide derivative that binds selectively to somatostatin receptors (mainly subtype 2), which are overexpressed on the surface of neuroendocrine tumor cells. This allows for specific targeting of these tumors. Synonyms: L-Threonine, N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide, acetate (salt) (1:x); DOTA-(Tyr3,Thr8)-Octreotide acetate; DOTA-[Tyr3] Octreotide Acid (Octreotate) acetate; DOTA-octreotate acetate; DOTA-[Tyr3]-Octreotide Acid acetate. Grade: 98%. CAS No. 177943-89-4. Molecular formula: C65H90N14O19S2.xC2H4O2. Mole weight: 1435.63 (free base). | |
| DOTATATE acetate | DOTATATE acetate is a DOTA-conjugated peptide. DOTATATE acetate can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT)[1][2][3][4]. DOTATATE (acetate) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Oxodotreotide acetate. CAS No. 177943-89-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106244A. | |
| DOTA-Thiol | DOTA-Thiolis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-Thiol can be used for conjugation of peptides and radionuclides. Uses: Scientific research. Category: Signaling pathways. CAS No. 865470-67-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W678394. | |
| DOTA-tris(tBu)ester NHS ester | DOTA-tris(tBu)ester NHS ester is a bifunctional precursor to a DOTA-based chelating agent. DOTA-tris(tBu)ester NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules, and upon deprotection forms stable complexes with metal ions for applications in molecular imaging[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 819869-77-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-131326. | |
| DOTA-tris(tert-butyl ester) | It is the PDC linker targeting moietie of peptide drug conjugates (PDCs). Synonyms: Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate; DOTA tri(tert-butyl) ester; DOTA(OBu-t)3; Tri-tert-Bu-DOTA; 2-(4,7,10-Tris(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid; DOTA(OtBu); 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 1,4,7-tris(1,1-dimethylethyl) ester; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, tris(1,1-dimethylethyl) ester; 1,4,7,10-Tetraazacyclododecane-1,4,7-tris-tert-butyl acetate-10-acetic acid. Grade: 95%. CAS No. 137076-54-1. Molecular formula: C28H52N4O8. Mole weight: 572.73. | |
| DOTA-tri(t-butyl ester) | DOTA-tri(t-butyl ester) belongs to the DOTA class of chelating agents. DOTA-tri(t-butyl ester) is a key raw material for synthesizing nanospherical magnetic resonance imaging (MRI) contrast agents, which are used in MR angiography and tumor angiogenesis imaging[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 137076-54-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W034551. | |
| DOTA-tri(t-butyl ester) | DOTA-tri(t-butyl ester). Alternative Names: Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate. CAS No. 137076-54-1. Purity: ≥99%. Product ID: ACM137076541-3. Molecular formula: C28H52N4O8. Mole weight: 572.73. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Dothiepin | Dothiepin (Dosulepin; Dothep) is an antidepressant agent with sedative/anxiolytic activity. Dothiepin is an inhibitor preferring of noradrenaline uptake than serotonin uptake. Dothiepin facilitates noradrenergic neurotransmission via inhibiting the neuronal uptake. Dothiepin is also an antagonist of histamine H1-receptor without cardiotoxicity. Dothiepin exhibits significant analgesic activity in psychogenic facial pain, idiopathic fibromyalgia syndrome or rheumatoid arthritis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dosulepin; Dothep. CAS No. 113-53-1. Pack Sizes: 1 mg. Product ID: HY-12394. | |
| Dothiepin | A tricyclic antidepressant. Group: Biochemicals. Alternative Names: 3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-. Grades: Highly Purified. CAS No. 113-53-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Dothiepin-d3 | Labeled Dothiepin. A tricyclic antidepressant. Group: Biochemicals. Alternative Names: 3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N-methyl-N-(methyl-d3)-. Grades: Highly Purified. CAS No. 136765-31-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Dothiepin-[d3] | Dothiepin-[d3] is the labelled analogue of Dothiepin, which is a tricyclic antidepressant. Synonyms: Dothiepin D3; 3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N-methyl-N-(methyl-d3)-1-propanamine; N,N-(Dimethyl-d3)-dibenzo[b,e]thiepin-11(6H), γ-propylamine-d3; Dosulepin-d3; Dosulepine-d3; Dothep-d3; Prothiaden-d3; Prothiadene-d3; cis-dothiepin-d3; Z-dothiepin-d3. Grade: ≥95%; ≥98% atom D. CAS No. 136765-31-6. Molecular formula: C19H18D3NS. Mole weight: 298.46. | |
| Dothiepin-[d3] Maleate | Dothiepin-[d3] Maleate is the labelled analogue of dothiepin. Dothiepin is a tricyclic antidepressant which is used in the treatment of depression. Synonyms: Dothiepin-d3 Maleate. Grade: 95% by HPLC; 98% atom D. Molecular formula: C23H22D3NO4S. Mole weight: 414.53. | |
| Dothiepin-[d6] HCl (N,N-dimethyl-[d6]) (cis/trans mixture) | Dothiepin-[d6] HCl is an isotope labelled form of Dothiepin hydrochloride. Dosulepin is a tricyclic antidepressant which is used in the treatment of depression. Synonyms: Dosulepin HCl; 3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine HCl. Grade: 95%+ by HPLC; 99% atom D. CAS No. 1276545-35-7. Molecular formula: C19H16D6ClNS. Mole weight: 337.94. | |
| Dotinurad Impurity 1 | Dotinurad Impurity 1. Uses: For analytical and research use. CAS No. 3336-41-2. Molecular formula: C7H4Cl2O3. Mole weight: 207.01. Catalog: APB3336412. |  |
| Dotinurad Impurity 10 | Dotinurad Impurity 10. Uses: For analytical and research use. Molecular formula: C15H11Cl2NO4S. Mole weight: 372.22. Catalog: APB12096. | |
| Dotinurad Impurity 11 | Dotinurad Impurity 11. Uses: For analytical and research use. Molecular formula: C21H11Cl4NO6S. Mole weight: 547.18. Catalog: APB12095. | |
| Dotinurad Impurity 12 | Dotinurad Impurity 12. Uses: For analytical and research use. Molecular formula: C21H12Cl3NO5S. Mole weight: 496.74. Catalog: APB12097. | |
| Dotinurad Impurity 2 | Dotinurad Impurity 2. Uses: For analytical and research use. CAS No. 37908-97-7. Molecular formula: C8H6Cl2O3. Mole weight: 221.03. Catalog: APB37908977. | |
| Dotinurad Impurity 3 | Dotinurad Impurity 3. Uses: For analytical and research use. CAS No. 29568-76-1. Molecular formula: C8H5Cl3O2. Mole weight: 239.48. Catalog: APB29568761. | |
| Dotinurad Impurity 4 | Dotinurad Impurity 4. Uses: For analytical and research use. CAS No. 1285573-42-3. Molecular formula: C15H11Cl2NO2S. Mole weight: 340.22. Catalog: APB1285573423. | |
| Dotinurad Impurity 5 | Dotinurad Impurity 5. Uses: For analytical and research use. CAS No. 1285573-47-8. Molecular formula: C15H11Cl2NO3S. Mole weight: 356.22. Catalog: APB1285573478. | |
| Dotinurad Impurity 6 | Dotinurad Impurity 6. Uses: For analytical and research use. CAS No. 1285573-44-5. Molecular formula: C15H11Cl2NO4S. Mole weight: 372.22. Catalog: APB1285573445. | |
| Dotinurad Impurity 7 | Dotinurad Impurity 7. Uses: For analytical and research use. CAS No. 1285572-55-5. Molecular formula: C14H9Cl2NO3S. Mole weight: 342.19. Catalog: APB1285572555. | |
| Dotinurad Impurity 8 | Dotinurad Impurity 8. Uses: For analytical and research use. Molecular formula: C14H11Cl2NO4S. Mole weight: 360.21. Catalog: APB12094. | |
| Dotinurad Impurity 9 | Dotinurad Impurity 9. Uses: For analytical and research use. Molecular formula: C28H18Cl4N2O8S2. Mole weight: 716.38. Catalog: APB12092. | |
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