A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Everninomicin B is a carbohydrate antibiotic produced by Micromonospora carbonacea var. carbonacea. It has anti-gram-positive bacteria and mycobacterial activity. Alternative Names: Everninomycin-B; R-451-B. CAS No. 53296-30-3. Molecular formula: C66H99Cl2NO36. Mole weight: 1553.38.
Everninomicin C
Everninomicin C is a carbohydrate antibiotic produced by Micromonospora carbonacea var. CAS No. 53296-29-0. Molecular formula: C63H93Cl2NO34. Mole weight: 1479.30.
Everninomicin D
Everninomicin D is a carbohydrate antibiotic produced by Micromonospora carbonacea var. carbonacea. It has anti-gram-positive bacteria and mycobacterial activity. Alternative Names: Flambamycin, 57-demethyl-45-O-de(2-methyl-1-oxopropyl)-59-deoxo-23-deoxy-59-methoxy-45-O-methyl-12-O-(2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitro-alpha-L-arabino-hexopyranosyl)-, (59S)-. CAS No. 39340-46-0. Molecular formula: C66H99Cl2NO35. Mole weight: 1537.38.
Everolimus is an immunosuppressant analog of rapamycin (sirolimus) and inhibits growth factor-mediated proliferation of hematopoietic and nonhematopoietic cells. Everolimus shows a potent inhibitory effect on posttransplant lymphoproliferative disorder (PTLD)-derived cells in vitro and in vivo, in a dose range that can prevent allograft rejection, and may demonstrate activity in both the prevention and treatment of PTLDs in transplant patients. Group: Biochemicals. Alternative Names: Afinitor, Certican, RAD-001, Zortress; 40-O- (2-Hydroxyethyl) rapamycin; 42-O-(2-Hydroxy)ethyl Rapamycin; RAD; RAD 001; SDZ-RAD; XIENCE V. Grades: Highly Purified. CAS No. 159351-69-6. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
Worldwide
Everolimus
Everolimus (RAD001) is a Rapamycin (HY-10219) derivative and a potent, selective, orally active, blood-brain barrier-permeable mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RAD001; SDZ-RAD. CAS No. 159351-69-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-10218.
Everolimus
Everolimus is an inhibitor of mammalian target of rapamycin (mTOR) with an immunosuppressive activity which is comparable to that of rapamycin. It inhibits cytokine-mediated lymphocyte proliferation. Everolimus can be used as an immunosuppressant in the treatment of renal cell cancer and other cancers. Uses: Immunosuppressant. Alternative Names: RAD-001; RAD001; RAD 001; Afinitor; Certican; Zortress; RAD001; SDZ-RAD. Grades: >98%. CAS No. 159351-69-6. Molecular formula: C53H83NO14. Mole weight: 958.24.
Everolimus-d4
Everolimus-d4 is the deuterium labeled Everolimus. Everolimus (RAD001) is a Rapamycin derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RAD001-d4; SDZ-RAD-d4. CAS No. 1338452-54-2. Pack Sizes: 500 μg; 1 mg. Product ID: HY-10218S.
Everolimus-d4
Macrolide immunosuppressant; derivative of Rapamycin. Inhibits cytokine-mediated lymphocyte proliferation. Group: Biochemicals. Alternative Names: 40-O-(2-Hydroxyethyl-d4)rapamycin; 42-O-(2-Hydroxy)ethyl-d4 Rapamycin; Afinitor-d4; Certican-d4; RAD-d4; RAD 001-d4; SDZ-RAD-d4; XIENCE V-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Everolimus-[d4]
Everolimus-[d4] is the labelled analogue of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Alternative Names: Everolimus D4; 40-O-(2-Hydroxyethyl-d4)rapamycin; 42-O-(2-Hydroxy)ethyl-d4 Rapamycin; Afinitor-d4; Certican-d4; RAD-d4; RAD 001-d4; SDZ-RAD-d4; XIENCE V-d4. Grades: 95% by HPLC; 95% atom D. CAS No. 1338452-54-2. Molecular formula: C53H79D4NO14. Mole weight: 962.25.
Everolimus EP Impurity B
An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Alternative Names: Everolimus 19-Ene Open-Ring Impurity; Everolimus Related Compound 2; seco Everolimus; (19E/Z)-seco-[4-O-(2-Hydroxyethyl)] Rapamycin. CAS No. 1062122-63-7. Molecular formula: C53H83NO14. Mole weight: 958.22.
Everolimus EP Impurity B
Everolimus EP Impurity B. Uses: For analytical and research use. CAS No. 1062122-63-7. Molecular formula: C53H83NO14. Mole weight: 958.24. Catalog: APB1062122637.
Everolimus EP Impurity B (19-Z-Isomer)
Everolimus EP Impurity B (19-Z-Isomer). Uses: For analytical and research use. CAS No. 763911-41-7. Molecular formula: C53H83NO14. Mole weight: 958.24. Catalog: APB763911417.
Everolimus EP Impurity C
An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Alternative Names: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18,19-trihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-30-methoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone; 19-O-demethyl everolimus. Molecular formula: C52H81NO14. Mole weight: 944.2.
Everolimus EP Impurity C
Everolimus EP Impurity C. Uses: For analytical and research use. Molecular formula: C52H81NO14. Mole weight: 944.21. Catalog: APB07747.
Everolimus EP Impurity D
An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Alternative Names: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1-hydroxy-18-(2-hydroxyethoxy)-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone; 18-O-hydroxyethyl sirolimus. Molecular formula: C53H83NO14. Mole weight: 958.22.
Everolimus EP Impurity D
Everolimus EP Impurity D. Uses: For analytical and research use. Molecular formula: C53H83NO14. Mole weight: 958.24. Catalog: APB07748.
Everolimus EP Impurity E
An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Alternative Names: (1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexylformate. CAS No. 1237826-25-3. Molecular formula: C52H79NO14. Mole weight: 942.18.
Everolimus EP Impurity E
Everolimus EP Impurity E. Uses: For analytical and research use. Alternative Names: Everolimus EP Impurity E. CAS No. 1237826-25-3. Molecular formula: C52H79NO14. Mole weight: 942.18. Catalog: APB1237826253.
Everolimus EP Impurity F
Everolimus EP Impurity F. Uses: For analytical and research use. Alternative Names: Everolimus EP Impurity F. Molecular formula: C55H89NO16. Mole weight: 1020.29. Catalog: APB05420.
Everolimus EP Impurity F
An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Alternative Names: (1R,9S,12S,15R,16E,18R,19S,20R,21R,23S,24S,25E,27Ξ,28E,30S,32S,35R)-27-ethoxy-1,18,20-trihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36,37-trioxa-4-azatetracyclo[30.3.1.120,24.04,9]heptatriaconta-16,25,28-triene-2,3,10,14-tetrone. Molecular formula: C55H89NO16. Mole weight: 1020.29.
Everolimus Impurity 003-09
Everolimus Impurity 003-09. Uses: For analytical and research use. Alternative Names: Everolimus Impurity 003-09. Molecular formula: C107H167N2O28. Mole weight: 1929.47. Catalog: APB05415.
Everolimus Impurity 005-98
Everolimus Impurity 005-98. Uses: For analytical and research use. Alternative Names: (1R,9S,12S,15R,16Z,18R,19R,21R,23S,24Z,26Z,28Z,30S,32S,35R)-1,18,30-Trihydroxy-12-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2-propanyl}-19-methoxy-15,17,21,23,29,35-hexamethyl-11,36 ; -dioxa-4-azatricyclo[30.3.1.0]hexatriaconta-16,24,26. CAS No. 745779-75-3. Molecular formula: C52H81NO14. Mole weight: 944.2. Catalog: APB745779753.
Everolimus Impurity 008-96
Everolimus Impurity 008-96. Uses: For analytical and research use. Alternative Names: Everolimus Impurity 008-96. Molecular formula: C54H85NO14. Mole weight: 972.25. Catalog: APB02224.
Everolimus Impurity 012-99
Everolimus Impurity 012-99. Uses: For analytical and research use. Alternative Names: (S)-(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-2,6,8-trimethyl-5,9-dioxonon-7-en-3-yl 1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2. CAS No. 1708118-13-1. Molecular formula: C53H83NO14. Mole weight: 958.22. Catalog: APB1708118131.
Everolimus Impurity 013-99
Everolimus Impurity 013-99. Uses: For analytical and research use. Alternative Names: (S)-1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic acid. CAS No. 147438-30-0. Molecular formula: C32H49NO9. Mole weight: 591.73. Catalog: APB147438300.
Everolimus Impurity 11
Everolimus Impurity 11. Uses: For analytical and research use. Alternative Names: 2-((tert-butyldimethylsilyl)oxy)ethyl trifluoromethanesulfonate. Molecular formula: C9H19F3O4SSi. Mole weight: 308.39. Catalog: APB05419.
EverolimusImpurity12
EverolimusImpurity12. Uses: For analytical and research use. Alternative Names: Everolimus Impurity 12. Molecular formula: C55H87NO15. Mole weight: 1002.28. Catalog: APB05418.
Everolimus Impurity 13
Everolimus Impurity 13. Uses: For analytical and research use. Alternative Names: Everolimus Impurity 13. Molecular formula: C53H83NO14. Mole weight: 958.22. Catalog: APB05417.
Everolimus Impurity 14
Everolimus Impurity 14. Uses: For analytical and research use. Alternative Names: Everolimus Impurity 14. Molecular formula: C53H83NO14. Mole weight: 958.22. Catalog: APB05416.
Everolimus Impurity 16
Everolimus Impurity 16. Uses: For analytical and research use. Molecular formula: C53H83NO14. Mole weight: 958.22. Catalog: APB02225.
Everolimus Impurity 211-97
Everolimus Impurity 211-97. Uses: For analytical and research use. Alternative Names: Everolimus Impurity 211-97. Molecular formula: C52H81NO14. Mole weight: 944.2. Catalog: APB05422.
Everolimus Impurity 23 (Everolimus-13C2-D4)
Everolimus Impurity 23 (Everolimus-13C2-D4). Uses: For analytical and research use. CAS No. 1661009-29-5. Molecular formula: C5113C2H79D4NO14. Mole weight: 964.25. Catalog: APB1661009295.
Everolimus Impurity 24 (Everolimus-D4)
Everolimus Impurity 24 (Everolimus-D4). Uses: For analytical and research use. CAS No. 1338452-54-2. Molecular formula: C53H79D4NO14. Mole weight: 962.26. Catalog: APB1338452542.
Everolimus Impurity 25
Everolimus Impurity 25. Uses: For analytical and research use. Molecular formula: C53H83NO14. Mole weight: 958.24. Catalog: APB07749.
Everolimus Impurity 26
Everolimus Impurity 26. Uses: For analytical and research use. Molecular formula: C32H49NO9. Mole weight: 591.74. Catalog: APB07750.
Everolimus Impurity 27
Everolimus Impurity 27. Uses: For analytical and research use. Molecular formula: C54H85NO14. Mole weight: 972.27. Catalog: APB07751.
Everolimus Impurity 28
Everolimus Impurity 28. Uses: For analytical and research use. Molecular formula: C54H85NO14. Mole weight: 972.27. Catalog: APB07752.
Everolimus Impurity 501-95
Everolimus Impurity 501-95. Uses: For analytical and research use. Alternative Names: Everolimus Impurity 501-95. Molecular formula: C53H83NO14. Mole weight: 958.22. Catalog: APB05421.
Everolimus Impurity 6
Everolimus Impurity 6. Uses: For analytical and research use. CAS No. 1704711-12-5. Molecular formula: C54H85NO14. Mole weight: 972.27. Catalog: APB1704711125.
Everolimus Impurity 7
Everolimus Impurity 7. Uses: For analytical and research use. CAS No. 2402744-97-0. Molecular formula: C53H83NO14. Mole weight: 958.24. Catalog: APB2402744970.
Everolimus Impurity 9-O-Hydroxyethyl sirolimus (009-96). Uses: For analytical and research use. Alternative Names: Everolimus Impurity 9-O-Hydroxyethyl sirolimus(009-96). Molecular formula: C53H83NO14. Mole weight: 958.22. Catalog: APB05424.
Everolimus Impurity Everolimus-19-ene open ring (804-95)
Everolimus Impurity Everolimus-19-ene open ring (804-95). Uses: For analytical and research use. Alternative Names: (S)-1-(2-((2R,3R,6S)-2-hydroxy-6-((2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19E,21R)-14-hydroxy-22-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15,19-pentaen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic acid. Molecular formula: C53H83NO14. Mole weight: 958.22. Catalog: APB05423.
Everolimus Isomer C
An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Alternative Names: 9,14-Deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-42-O-(2-hydroxyethyl)-14-oxorapamycin. Grades: 80%. CAS No. 908340-97-6. Molecular formula: C53H83NO14. Mole weight: 958.25.
Everolimus O-Ethyl Impurity
An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Alternative Names: 7-O-Desmethyl-7-O-ethyl Everolimus. Grades: > 95%. CAS No. 1704711-12-5. Molecular formula: C54H85NO14. Mole weight: 972.28.
Everolimus Open-Ring Acid Impurity
Everolimus Open-Ring Acid Impurity. Uses: For analytical and research use. CAS No. 769905-89-7. Molecular formula: C53H85NO15. Mole weight: 976.25. Catalog: APB769905897.
Everolimus Related Compound 1
An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Alternative Names: O-Desmethyl Everolimus. Grades: > 95%. CAS No. 745779-75-3. Molecular formula: C52H81NO14. Mole weight: 944.22.
An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Alternative Names: Di-tert-butyl-4-methylene-2,5-cyclohexadienone; 2,6-Di-t-butyl-4-methylene-2,5-cyclohexadienone. Grades: > 95%. CAS No. 2607-52-5. Molecular formula: C15H22O. Mole weight: 218.34.
Everolimus Related Compound 5
Everolimus Related Compound 5. Uses: For analytical and research use. CAS No. 2607-52-5. Molecular formula: C15H22O. Mole weight: 218.34. Catalog: APB2607525.
Everolimus Ring-Opening Impurity
An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Alternative Names: Everolimus Retroaldol Degradation Product. Grades: 90% (Mixture of isomers). CAS No. 1708118-13-1. Molecular formula: C53H83NO14. Mole weight: 958.25.
Evinacumab
Evinacumab (REGN1500) is a human anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: REGN1500. CAS No. 1446419-85-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99194.
Evixapodlin
Evixapodlin is a human programmed cell death ligand 1 (PD-1/PD-L1) protein / protein interaction inhibitor with an IC50 of 0.213 nM. It has anticancer and antiviral functions. Alternative Names: (12S,122S)-62,72-dichloro-53,86-dimethoxy-3,10-diaza-5,8(2,5)-dipyrazina-1,12(2)-dipyrrolidina-6,7(1,3)-dibenzenadodecaphane-15,125-dione; (5S,5'S)-5,5'-((((5,5'-(2,2'-dichloro-[1,1'-biphenyl]-3,3'-diyl)bis(3-methoxypyrazine-5,2-diyl))bis(methylene))bis(azanediyl))bis(methylene))bis(pyrrolidin-2-one); 2-Pyrrolidinone, 5,5'-[(2,2'-dichloro[1,1'-biphenyl]-3,3'-diyl)bis[(3-methoxy-5,2-pyrazinediyl)methyleneiminomethylene]]bis-, (5S,5'S)-; PD-1/PD-L1-IN 7. Grades: ≥98%. CAS No. 2374856-75-2. Molecular formula: C34H36Cl2N8O4. Mole weight: 691.61.
Evixapodlin
Evixapodlin (GS-4224) is a human PD-1/PD-L1 protein/protein interaction inhibitor with an IC50 of 0.213 nM. Evixapodlin has anticancer and antiviral functions[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS-4224; PD-1/PD-L1-IN 7. CAS No. 2374856-75-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138407.
Evobrutinib
Evobrutinib (M2951) is an orally active, potent, highly selective and irreversibly covalent BTK inhibitor, with an IC50 of 8.9 nM. Evobrutinib (M2951) can be used for the research of autoimmune diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: M2951; MSC2364447C. CAS No. 1415823-73-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101215.
Evocalcet
Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KHK7580. CAS No. 870964-67-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17613.
Evodenoson
Evodenoson is a selective agonist of the A2A adenosine receptor. Evodenosons primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenosons protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ATL 313; DE 112. CAS No. 844873-47-8. Pack Sizes: 1 mg. Product ID: HY-105017.
Evodiamine
Evodiamine. Alternative Names: [13bS,(+)]-8,13,13b,14-Tetrahydro-14-methylindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one. CAS No. 518-17-2. Purity: >98.0%. Product ID: FFC-AR-518172. Molecular formula: C19H17N3O. Mole weight: 303.36. IUPAC Name: (1S)-21-methyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,15,17,19-heptaen-14-one. Alfa Chemistry - ISO 9001:32057 Certified.
Evodiamine
Evodiamine (Isoevodiamine), an alkaloid extract from the fruit of Evodiae Fructus exhibits antitumor activities against the human tumor cells. Evodiamine is a natural compound used in cosmetics material. Uses: Anti-oxidation; anti-inflammatory; anti-cancer. Alternative Names: Isoevodiamine; Evodiamine; Q-100579; Q100579; Q 100579; SC-16015; SC16015; SC 16015. Grades: >98%. CAS No. 518-17-2. Molecular formula: C19H17N3O. Mole weight: 303.36.
Evodiamine
A chemical extracted from Evodia plants, and has been shown to reduce fat uptake. Group: Biochemicals. Alternative Names: (13bS)-8, 13, 13b-14-Tetrahydro-14-methyl-indolo[2', 3':3, 4]pyrido[2, 1-b]quinazolin-5(7H)-one; d-Evodiamine; (+)-Evodiamine. Grades: Highly Purified. CAS No. 518-17-2. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Evodiamine
Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor. Uses: Scientific research. Category: Natural products. Alternative Names: (+)-Evodiamine; d-Evodiamine. CAS No. 518-17-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg. Product ID: HY-N0114.
Evodiamine 98% HPLC
Evodiamine 98% HPLC.
CA, FL & NJ
Evofosfamide
Evofosfamide (TH-302) is a hypoxia-activated proagent with IC50 of 10 μM and 1000 μM in hypoxia (N2) and normoxia (21% O2), respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TH-302. CAS No. 918633-87-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10535.
Evofosfamide
Evofosfamide is a hypoxia-activated prodrug consisting of a 2-nitroimidazole phosphoramidate conjugate with potential antineoplastic activity. The 2-nitroimidazole moiety of hypoxia-activated prodrug TH-302 acts as a hypoxic trigger, releasing the DNA-alkylating dibromo isophosphoramide mustard moiety within hypoxic regions of tumors. Normoxic tissues may be spared due to the hypoxia-specific activity of this agent, potentially reducing systemic toxicity. Alternative Names: TH-302; TH 302; TH302; 2-bromo-N-[(2-bromoethylamino)-[(3-methyl-2-nitroimidazol-4-yl)methoxy]phosphoryl]ethanamine. Grades: > 98%. CAS No. 918633-87-1. Molecular formula: C9H16Br2N5O4P. Mole weight: 449.04.
Evogliptin
Evogliptin (DA-1229) is a DPP4 inhibitor with oral activity. Evogliptin has significant and lasting hypoglycemic effect in mouse model. Evogliptin inhibits the production of the fibrosis and inflammatory in hepatocytes signals by inducing autophagy. Evogliptin can be used to study type 2 diabetes, chronic liver inflammation, osteoporosis and renal impairment. Category: Active pharmaceutical ingredients. CAS No. 1222102-29-5. Product ID: API1222102295. Molecular formula: C19H26F3N3O3. Mole weight: 401.42.
Evogliptin HCl
Evogliptin(DA-1229) is a potent and selective DPP4 inhibitor (dipeptidyl peptidase 4 inhibitor) that can improve insulin resistance and delays the onset of diabetes. Evogliptin delays the onset of diabetes in young db/db mice and improves insulin sensitiv. Category: Active pharmaceutical ingredients. CAS No. 1246960-27-9. Product ID: API1246960279. Molecular formula: C19H27ClF3N3O3. Mole weight: 437.88.
Evogliptin tartrate
Evogliptin tartrate has potential for anti-atherosclerosis therapy that targets arterial inflammation. Evogliptin tartrate is a potent, orally bioavailable and selective dipeptidyl peptidase-4 (DPP-4) inhibitor, with antidiabetic activity. Category: Active pharmaceutical ingredients. Synonyms: DA-1229 tartrate. CAS No. 1222102-51-3. Product ID: API1222102513. Molecular formula: C23H32F3N3O9. Mole weight: 551.51.
Evogliptin tartrate
Evogliptin (DA-1229) tartrate is an orally active DPP4 inhibitor with significant and sustained hypoglycaemic effects in mouse models. Evogliptin tartrate also inhibits the production of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin tartrate can be used in studies of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DA-1229 tartrate. CAS No. 1222102-51-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117985B.
Evolitrine
Evolitrine is an alkaloid isolated from Fructus Evodiae. Alternative Names: Evolitrin; 4,7-dimethoxyfuro[2,3-b]quinoline. Grades: 98%. CAS No. 523-66-0. Molecular formula: C13H11NO3. Mole weight: 229.23.