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| Product | Description | |
|---|---|---|
| Exemestane | Exemestane is an irreversible, steroidal aromatase inhibitor used in the treatment of estrogen receptor-positive (ER+) breast cancer in postmenopausal women. As a mechanism-based inactivator of aromatase (CYP19), it reduces estrogen synthesis by permanently binding to the active site of the enzyme, thereby depriving hormone-sensitive tumor cells of estrogen-driven growth stimulation. Applications: Exemestane is indicated for the adjuvant treatment of estrogen receptor-positive early breast cancer in postmenopausal women following initial adjuvant tamoxifen therapy, and for the treatment of advanced estrogen receptor-positive breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy. Category: Active pharmaceutical ingredients. Synonyms: 1,4-Androstadien-3,17-dione-6-Methylene-d2;(8R,9S,10R,13S,14S)-10,13-Dimethyl-6-methylene-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17(10H,14H)-dione;ExeMestine. CAS No. 107868-30-4. Product ID: API107868304. Molecular formula: C20H24O2. Mole weight: 296.4. EINECS: 643-090-2. InChIKey: BFYIZQONLCFLEV-DAELLWKTSA-N. Appearance: White to off-white powder. |  |
| Exemestane | Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FCE 24304; EXE. CAS No. 107868-30-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13632. |  |
| Exemestane-[d2] | Exemestane-[d2] is a deuterium labelled analogue of Exemestane. Exemestane is a medication used for the treatment of certain types of breast cancer. It acts via inhibiting estrogen essential for some breast cancers' growth. Synonyms: 6-Methyleneandrosta-1,4-diene-3,17-dione-16,16-D2; Exemestane D2; (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylene-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione-16,16-d2; Aromasin-d2; Aromasine-d2; Exemestano-d2. Grade: 99.6% by HPLC; 99% atom D. Molecular formula: C20H22D2O2. Mole weight: 298.38. |  |
| Exemestane-d3 | One of the isotopic labelled form of Exemestane, which is a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Methyleneandrosta-1,4-diene-3,17-dione-d3. Molecular formula: C20H21O2D3. Mole weight: 299.43. | |
| Exemestane-d5 | One of the isotopic labelled form of Exemestane, which is a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Methyleneandrosta-1,4-diene-3,17-dione-d5. Molecular formula: C20H19O2D5. Mole weight: 301.44. | |
| Exemestane EP Impurity B | Exemestane EP Impurity B. Uses: For analytical and research use. CAS No. 184972-09-6. Molecular formula: C20H26O3. Mole weight: 314.43. Catalog: APB184972096. |  |
| Exemestane EP Impurity C | Exemestane EP Impurity C. Uses: For analytical and research use. CAS No. 2130745-60-5. Molecular formula: C21H24O2. Mole weight: 308.42. Catalog: APB2130745605. | |
| Exemestane EP Impurity E | Exemestane EP Impurity E. Uses: For analytical and research use. CAS No. 19457-55-7. Molecular formula: C20H26O2. Mole weight: 298.43. Catalog: APB19457557. | |
| Exemestane EP Impurity F | Exemestane EP Impurity F. Uses: For analytical and research use. Alternative Names: (8R,9S,10R,13S,14S)-10,13-Dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,6,17-trione. CAS No. 72648-46-5. Molecular formula: C19H22O3. Mole weight: 298.38. Catalog: APB72648465. | |
| Exemestane EP Impurity H | Exemestane EP Impurity H. Uses: For analytical and research use. CAS No. 122370-91-6. Molecular formula: C20H26O2. Mole weight: 298.43. Catalog: APB122370916. | |
| Exemestane EP Impurity I | Exemestane EP Impurity I. Uses: For analytical and research use. Molecular formula: C21H26O3. Mole weight: 326.44. Catalog: APB07754. | |
| Exemestane EP Impurity J | Exemestane EP Impurity J. Uses: For analytical and research use. CAS No. 1160599-91-6. Molecular formula: C22H28O3. Mole weight: 340.46. Catalog: APB1160599916. | |
| Exemestane Impurity 1 | Exemestane Impurity 1. Uses: For analytical and research use. CAS No. 159354-61-7. Molecular formula: C20H24O3. Mole weight: 312.41. Catalog: APB159354617. | |
| Exemestane Impurity 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 1,2-α-Epoxy Exemestane; (1α,2α)-1,2-Epoxy-6-methyleneandrost-4-ene-3,17-dione. Grade: > 95%. CAS No. 159354-61-7. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Impurity 10 | Exemestane Impurity 10. Uses: For analytical and research use. CAS No. 881896-95-3. Molecular formula: C21H28O3. Mole weight: 328.45. Catalog: APB881896953. | |
| Exemestane Impurity 10 | Exemestane Impurity 10. Uses: For analytical and research use. Alternative Names: ((8R,9S,10R,13S,14S)-10,13-dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-6-yl)methyl 4-methylbenzenesulfonate. Molecular formula: C27H32O5S. Mole weight: 468.6. Catalog: APB05409. | |
| Exemestane Impurity 11 | Exemestane Impurity 11. Uses: For analytical and research use. Alternative Names: (8R,9S,10R,13S,14S)-6-(ethoxymethyl)-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)-dione. Molecular formula: C22H32O3. Mole weight: 344.49. Catalog: APB05407. | |
| Exemestane Impurity 11 | Exemestane Impurity 11. Uses: For analytical and research use. CAS No. 107868-36-0. Molecular formula: C20H23ClO2. Mole weight: 330.85. Catalog: APB107868360. | |
| Exemestane Impurity 12 | Exemestane Impurity 12. Uses: For analytical and research use. Alternative Names: ((8R,9S,10R,13S,14S)-10,13-dimethyl-3,17-dioxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-6-yl)methyl 4-methylbenzenesulfonate. Molecular formula: C27H34O5S. Mole weight: 470.62. Catalog: APB05408. | |
| Exemestane Impurity 13 | Exemestane Impurity 13. Uses: For analytical and research use. Alternative Names: (4aR,4bS,6aS,9aS,9bR)-4a,6a-dimethyl-11-methylene-4b,5,6,6a,8,9,9a,9b,10,11-decahydrocyclopenta[7,8]phenanthro[1,10a-b]oxirene-2,7(1aH,4aH)-dione. Molecular formula: C20H24O3. Mole weight: 312.4. Catalog: APB05406. | |
| Exemestane Impurity 13 | Exemestane Impurity 13. Uses: For analytical and research use. CAS No. 152764-29-9. Molecular formula: C20H26O3. Mole weight: 314.43. Catalog: APB152764299. | |
| Exemestane Impurity 14 | Exemestane Impurity 14. Uses: For analytical and research use. Alternative Names: (3S,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5,6-dimethylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol. Molecular formula: C28H48O. Mole weight: 400.68. Catalog: APB05405. | |
| Exemestane Impurity 15 | Exemestane Impurity 15. Uses: For analytical and research use. Alternative Names: (3S,8S,9S,10R,13R,14S,17R)-17-((2R,5S,E)-5-ethyl-6-methylhept-3-en-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol. Molecular formula: C29H48O. Mole weight: 412.69. Catalog: APB05404. | |
| Exemestane Impurity 15 | Exemestane Impurity 15. Uses: For analytical and research use. CAS No. 67737-88-6. Molecular formula: C27H40N2O. Mole weight: 408.63. Catalog: APB67737886. | |
| Exemestane Impurity 16 | Exemestane Impurity 16. Uses: For analytical and research use. Alternative Names: (3S,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol. CAS No. 83-46-5. Molecular formula: C29H50O. Mole weight: 414.71. Catalog: APB83465. | |
| Exemestane Impurity 16 | Exemestane Impurity 16. Uses: For analytical and research use. CAS No. 184972-11-0. Molecular formula: C20H26O4. Mole weight: 300.42. Catalog: APB184972110. | |
| Exemestane Impurity 2 | Exemestane Impurity 2. Uses: For analytical and research use. CAS No. 2467590-81-2. Molecular formula: C20H24O2. Mole weight: 296.41. Catalog: APB2467590812. | |
| Exemestane Impurity 3 | Exemestane Impurity 3. Uses: For analytical and research use. CAS No. 1012054-48-6. Molecular formula: C20H28O3. Mole weight: 316.44. Catalog: APB1012054486. | |
| Exemestane Impurity 3 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6,16-Dimethylideneandrosta-1,4-diene-3,17-dione. Grade: > 95%. Molecular formula: C21H24O2. Mole weight: 308.42. | |
| Exemestane Impurity 4 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 16-methylideneandrosta-1,4-diene-3,17-dione. Grade: > 95%. Molecular formula: C20H24O2. Mole weight: 296.41. | |
| Exemestane Impurity 5 | Exemestane Impurity 5. Uses: For analytical and research use. Molecular formula: C20H24O2. Mole weight: 296.41. Catalog: APB07755. | |
| Exemestane Impurity 6 | Exemestane Impurity 6. Uses: For analytical and research use. CAS No. 1331732-05-8. Molecular formula: C20H26O3. Mole weight: 314.43. Catalog: APB1331732058. | |
| Exemestane Impurity 8 (Testosterone Impurity 6) | Exemestane Impurity 8 (Testosterone Impurity 6). Uses: For analytical and research use. CAS No. 1035-69-4. Molecular formula: C19H24O2. Mole weight: 284.4. Catalog: APB1035694. | |
| Exemestane Impurity E | Exemestane Impurity E. Uses: For analytical and research use. Alternative Names: (2'R,8R,9S,10R,13S,14S)-10,13-dimethyl-7,8,9,11,12,13,15,16-octahydrospiro[cyclopenta[a]phenanthrene-6,2'-oxirane]-3,17(10H,14H)-dione. CAS No. 152764-24-4. Molecular formula: C20H24O3. Mole weight: 312.4. Catalog: APB152764244. | |
| Exemestane Impurity G | Exemestane Impurity G. Uses: For analytical and research use. Alternative Names: (2'S,8R,9S,10R,13S,14S)-10,13-dimethyl-7,8,9,11,12,13,15,16-octahydrospiro[cyclopenta[a]phenanthrene-6,2'-oxirane]-3,17(10H,14H)-dione. CAS No. 152764-31-3. Molecular formula: C20H24O3. Mole weight: 312.4. Catalog: APB152764313. | |
| Exemestane Impurity H | Exemestane Impurity H. Uses: For analytical and research use. Alternative Names: (8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-6-methylene-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one. Molecular formula: C20H26O2. Mole weight: 298.42. Catalog: APB05414. | |
| Exemestane Impurity I | Exemestane Impurity I. Uses: For analytical and research use. Alternative Names: (8R,9S,10R,13S,14S,17S)-10,13-dimethyl-6-methylene-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl formate. Molecular formula: C21H26O3. Mole weight: 326.43. Catalog: APB05412. | |
| Exemestane Impurity J | Exemestane Impurity J. Uses: For analytical and research use. Alternative Names: (8R,9S,10R,13S,14S,17S)-10,13-dimethyl-6-methylene-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl acetate. Molecular formula: C22H28O3. Mole weight: 340.46. Catalog: APB05413. | |
| Exemestane Impurity JQ | Exemestane Impurity JQ. Uses: For analytical and research use. Alternative Names: (8R,9S,10R,13S,14S)-6-hydroxy-6,10,13-trimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione. Molecular formula: C20H26O3. Mole weight: 314.42. Catalog: APB05411. | |
| Exemestane Impurity SHY | Exemestane Impurity SHY. Uses: For analytical and research use. Alternative Names: (2aS,3aS,3bR,3cS,5aS,8aS,8bR)-3b,5a-dimethyl-3b,3c,4,5,5a,7,8,8a,8b,9-decahydrospiro[cyclopenta[7,8]phenanthro[3,4-b]oxirene-10,2'-oxirane]-2,6(2aH,3aH)-dione. Molecular formula: C20H24O4. Mole weight: 328.4. Catalog: APB05410. | |
| Exemestane Metabolite 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17β-Hydroxy Exemestane Sulfamate; (17β)-17-[(Aminosulfonyl)oxy]-6-methyleneandrosta-1,4-dien-3-one. Grade: > 95%. Molecular formula: C20H27NO4S. Mole weight: 377.51. | |
| Exemestane Metabolite 2 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Hydroxy-6-(methoxymethyl)-androsta-1,4-diene-3,17-dione. Grade: > 95%. Molecular formula: C21H28O4. Mole weight: 344.45. | |
| Exemestane Related Compound | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6α-(Methoxymethyl)androsta-1,4-dien-3,17-dione. Grade: > 95%. CAS No. 881896-95-3. Molecular formula: C21H28O3. Mole weight: 328.46. | |
| Exemestane Related Compound 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6β-(Formyl)androsta-1,4-dien-3,17-dione. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 | Exemestane Related Compound 2. Uses: For analytical and research use. CAS No. 121021-51-0. Molecular formula: C20H26O3. Mole weight: 314.43. Catalog: APB121021510. | |
| Exemestane Related Compound 2 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 (17-alpha isomer) | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-alpha-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 (17-beta isomer) | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-beta-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 3 | Exemestane Related Compound 3. Uses: For analytical and research use. CAS No. 933455-73-3. Molecular formula: C21H28O3. Mole weight: 328.45. Catalog: APB933455733. | |
| Exemestane Related Compound A | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 1,2-Dihydro Exemestane; 6-Methyleneandrost-4-ene-3,17-dione; 6-Methyleneandrost-4-en-3,17-dione. Grade: > 95%. CAS No. 19457-55-7. Molecular formula: C20H26O2. Mole weight: 298.43. | |
| Exemestane Related Compound A | Exemestane Related Compound A. Uses: For analytical and research use. CAS No. 19457-55-7. Mole weight: 298.42. Catalog: AP19457557. | |
| Exemestane Related Compound B | Isotope labelled Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: Androsta-1,4-diene-3,17-dione, 6-(hydroxymethyl). Grade: > 95%. CAS No. 184972-09-6. Molecular formula: C20H26O3. Mole weight: 314.43. | |
| Exemestane Related Compound B | Exemestane Related Compound B. Uses: For analytical and research use. CAS No. 184972-09-6. Mole weight: 314.42. Catalog: AP184972096. | |
| Exenatide | Exenatide, naturally occured in the saliva of the Gila monster, an incretin mimetic that has glucoregulatory effect. As a glucagon-like peptide-1 (GLP-1) receptor agonist, it stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways. Uses: Hypoglycemic agents. Synonyms: L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-; L-. CAS No. 141758-74-9. Molecular formula: C184H282N50O60S. Mole weight: 4186.56. | |
| Exenatide acetate | Exenatide acetate is a potent peptide agonist of the glucagon-like peptide 1 (GLP-1) receptor with Ki value of 136 pM. It is a 39 amino acid peptide, which increases intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors. It was first isolated from the venom of H. horridum and consequently synthesized. It stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways via a GLP-1 receptor-dependent mechanism. It also stimulates glucose-induced insulin secretion in isolated rat islets and proinsulin expression in mouse insulinoma βTC-1 cells. It protects hippocampal neurons against glutamate-induced apoptosis, suggesting utility in neurodegenerative diseases. It also has anxiolytic and anti-depressant effects and induces satiety. It is an incretin mimetic approved for type 2 diabetes mellitus treatment. It also has neurotrophic/protective activity in cellular and animal models of stroke, Alzheimer's and Parkinson's diseases. Synonyms: L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-, ac. Grade: >9 | |
| Exenatide acetate | Exenatide acetate. Group: Biochemicals. Alternative Names: Exendin-4. Grades: Highly Purified. CAS No. 141732-76-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C184H282N50O60S·C2H4O2. US Biological Life Sciences. |  Worldwide |
| Exendin-3 | Exendin-3 is a bioactive peptide isolated from venoms of the Gila monster lizards, Heloderma horridurn. Synonyms: H-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2; L-histidyl-L-seryl-L-alpha-aspartyl-glycyl-L-allothreonyl-L-phenylalanyl-L-allothreonyl-L-seryl-L-alpha-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparagyl-glycyl-glycyl-L-prolyl-L-seryl-L-seryl-glycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-L-serinamide. Grade: ≥95%. CAS No. 130357-25-4. Molecular formula: C184H282N50O61S. Mole weight: 4202.57. | |
| Exendin 3 (9-39) | Exendin (9-39) is a specific and competitive glucagon-like peptide-1receptor antagonist (Kd = 1.7 nM at cloned human GLP-1 receptors). Exendin (9-39) inhibits insulin release and cAMP production caused by GLP-1 (7-36), exendin-3, and exendin-4. Synonyms: Exendin 9-39; Exendin 9 39; H-DL-Asp-DL-Leu-DL-Ser-DL-Lys-DL-Gln-DL-Met-DL-Glu-DL-Glu-DL-Glu-DL-Ala-DL-Val-DL-Arg-DL-Leu-DL-Phe-DL-xiIle-DL-Glu-DL-Trp-DL-Leu-DL-Lys-DL-Asn-Gly-Gly-DL-Pro-DL-Ser-DL-Ser-Gly-DL-Ala-DL-Pro-DL-Pro-DL-Pro-DL-Ser-NH2; DL-alpha-aspartyl-DL-leucyl-DL-seryl-DL-lysyl-DL-glutaminyl-DL-methionyl-DL-alpha-glutamyl-DL-alpha-glutamyl-DL-alpha-glutamyl-DL-alanyl-DL-valyl-DL-arginyl-DL-leucyl-DL-phenylalanyl-DL-isoleucyl-DL-alpha-glutamyl-DL-tryptophyl-DL-leucyl-DL-lysyl-DL-asparagyl-glycyl-glycyl-DL-prolyl-DL-seryl-DL-seryl-glycyl-DL-alanyl-DL-prolyl-DL-prolyl-DL-prolyl-DL-serinamide. Grade: ≥95%. CAS No. 133514-43-9. Molecular formula: C149H234N40O47S. Mole weight: 3369.76. | |
| Exendin-3 (9-39) amide | Exendin-3 (9-39) amide. Group: Biochemicals. Grades: Purified. CAS No. 133514-43-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Exendin-4 | Exendin-4. Group: Biochemicals. Grades: Highly Purified. CAS No. 141758-74-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Exendin-4 | Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Exenatide. CAS No. 141758-74-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13443. | |
| Exendin-4 (1-8) | Exendin-4 (1-8). Synonyms: H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-NH2; L-Histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-serinamide. Grade: ≥95%. CAS No. 1802078-29-0. Molecular formula: C35H51N11O13. Mole weight: 833.84. | |
| EXENDIN-4 (3-39) | Exendin-4 (3-39) is a potent glucagon-like peptide 1 (GLP-1) receptor antagonist. Synonyms: H-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Grade: 95%. CAS No. 196109-31-6. Molecular formula: C176H272N46O58S. Mole weight: 3992.44. | |
| Exendin-4 (5-39) | Exendin-4 (5-39) is a potent Glucagon-Like Peptide 1 (GLP-1) receptor antagonist. Synonyms: H-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. CAS No. 196109-27-0. Molecular formula: C169H262N44O54S. Mole weight: 3806.30. | |
| Exendin-4 acetate | Exendin-4 acetate (Exenatide acetate), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Exenatide acetate. CAS No. 914454-01-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-13443A. | |
| Exendin(9-39) amide | Exendin(9-39) amide (Avexitide) is a glucagon-like peptide-1 (GLP-1) antagonist that competes with endogenous GLP-1 for binding to GLP-1 receptors, thereby antagonizing the effects of excess GLP-1 secretion. Exendin(9-39) amide can be used to study postoperative hypoglycemia (PBH)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Avexitide. CAS No. 133514-43-9. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0264. | |
| Exendin(9-39) amide acetate | Exendin(9-39) amide (Avexitide) acetate is a glucagon-like peptide-1 (GLP-1) antagonist that competes with endogenous GLP-1 for the GLP-1R, counteracting the effects of excessive GLP-1 secretion. Exendin(9-39) amide acetate can be utilized in Postbariatric hypoglycemia (PBH) research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Avexitide acetate. CAS No. 2051593-46-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0264A. | |
| Exendin derivative 1 | Exendin derivative 1 is a peptide consisting of 39 amino acids. Synonyms: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-OH; L-histidyl-alanyl-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparagyl-glycyl-glycyl-L-prolyl-L-seryl-L-seryl-glycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-L-serine. Grade: ≥95%. Molecular formula: C184H281N49O61S. Mole weight: 4187.56. | |
| Exeporfinium chloride | Exepor?nium is an anti-microbial that works via weakening bacteria cell walls. It can be used for the treatment for MRSA (methicillin-resistant Staphylococcus aureus) and possibly Clostridium difficile. In Apr 2016, Destiny Pharma completed a phase I/II trial in Staphylococcal infections in USA. Uses: Staphylococcal infections. Synonyms: XF73; XF 73; XF-73; 3,3'-((porphyrin-5,15-diylbis(4,1-phenylene))bis(oxy))bis(N,N,N-trimethylpropan-1-aminium) chloride; 756818-36-7 (XF-73 Free). Grade: 98%. CAS No. 718638-68-7. Molecular formula: C44H50Cl2N6O2. Mole weight: 765.82. | |
| Exfoliamycin | Exfoliamycin is a naphthoquinone antibiotic produced by Streptomyces exfoliamycin Tu 1424. Activity against gram-positive bacteria. Synonyms: 1H-Naphtho(2,3-c)pyran-6,9-dione, 3,4-dihydro-3,10-dihydroxy-3-methyl-8-pentofuranosyl-1-propyl-. CAS No. 148084-37-1. Molecular formula: C22H26O9. Mole weight: 434.44. | |
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