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| Product | Description | |
|---|---|---|
| Ezetimibe Impurity 49 | Ezetimibe Impurity 49. Uses: For analytical and research use. Alternative Names: dihydro-2H-pyran-2,6(3H)-dione. CAS No. 108-55-4. Molecular formula: C5H6O3. Mole weight: 114.1. Catalog: APB108554. |  |
| Ezetimibe Impurity 5 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L20) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)azetidin-2-one. Grade: > 95%. Molecular formula: C31H27F2NO3. Mole weight: 499.56. |  |
| Ezetimibe Impurity 51 | Ezetimibe Impurity 51. Uses: For analytical and research use. Alternative Names: tert-butyldimethylsilanol. CAS No. 18173-64-3. Molecular formula: C6H16OSi. Mole weight: 132.28. Catalog: APB18173643. | |
| Ezetimibe Impurity 52 | Ezetimibe Impurity 52. Uses: For analytical and research use. Alternative Names: 4-(((tert-butyldimethylsilyl)(4-fluorophenyl)amino)methylene)cyclohexa-2,5-dienone. Molecular formula: C19H24FNOSi. Mole weight: 329.48. Catalog: APB05293. | |
| Ezetimibe Impurity 53 | Ezetimibe Impurity 53. Uses: For analytical and research use. Alternative Names: (S)-3-((2R,5S)-5-((tert-butyldimethylsilyl)oxy)-5-(4-fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)pentanoyl)-4-phenyloxazolidin-2-one. Molecular formula: C39H44F2N2O5Si. Mole weight: 686.86. Catalog: APB05373. | |
| Ezetimibe Impurity 54 | Ezetimibe Impurity 54. Uses: For analytical and research use. Alternative Names: (S)-3-((2R,5S)-2-((S)-(4-((tert-butyldimethylsilyl)oxy)phenyl)((4-fluorophenyl)amino)methyl)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one. CAS No. 1185883-46-8. Molecular formula: C39H44F2N2O5Si. Mole weight: 686.86. Catalog: APB1185883468. | |
| Ezetimibe Impurity 55 | Ezetimibe Impurity 55. Uses: For analytical and research use. Alternative Names: (3R,4S)-4-(4-((tert-butyldimethylsilyl)oxy)phenyl)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)azetidin-2-one. CAS No. 942485-60-1. Molecular formula: C30H35F2NO3Si. Mole weight: 523.69. Catalog: APB942485601. | |
| Ezetimibe Impurity 56 | Ezetimibe Impurity 56. Uses: For analytical and research use. Alternative Names: (3R,4S)-3-((S)-3-((tert-butyldimethylsilyl)oxy)-3-(4-fluorophenyl)propyl)-1-(4-fluorophenyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 795306-57-9. Molecular formula: C30H35F2NO3Si. Mole weight: 523.69. Catalog: APB795306579. | |
| Ezetimibe Impurity 57 | Ezetimibe Impurity 57. Uses: For analytical and research use. Alternative Names: (S)-3-(5-(4-fluorophenyl)pentanoyl)-4-phenyloxazolidin-2-one. Molecular formula: C20H20FNO3. Mole weight: 341.38. Catalog: APB05372. | |
| Ezetimibe Impurity 59 | Ezetimibe Impurity 59. Uses: For analytical and research use. Alternative Names: (S)-1-(2-fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione. Molecular formula: C20H18FNO4. Mole weight: 355.36. Catalog: APB05371. | |
| Ezetimibe Impurity 60 | Ezetimibe Impurity 60. Uses: For analytical and research use. Alternative Names: 4-((2S,3R)-3-((S)-3-acetoxy-3-(4-fluorophenyl)propyl)-1-(4-fluorophenyl)-4-oxoazetidin-2-yl)phenyl acetate. CAS No. 163380-20-9. Molecular formula: C28H25F2NO5. Mole weight: 493.5. Catalog: APB163380209. | |
| Ezetimibe Impurity 61 | Ezetimibe Impurity 61. Uses: For analytical and research use. Alternative Names: (S)-3-((2R,5S)-5-(4-fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one. CAS No. 272778-12-8. Molecular formula: C39H46F2N2O5Si2. Mole weight: 716.96. Catalog: APB272778128. | |
| Ezetimibe Impurity 62 | Ezetimibe Impurity 62. Uses: For analytical and research use. Alternative Names: 4-((2S,3R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-oxoazetidin-2-yl)phenyl acetate. Molecular formula: C26H23F2NO4. Mole weight: 451.46. Catalog: APB05370. | |
| Ezetimibe Impurity 63 | Ezetimibe Impurity 63. Uses: For analytical and research use. Alternative Names: (S)-3-((2R,5S)-5-(4-fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one. CAS No. 1185883-40-2. Molecular formula: C33H30F2N2O5. Mole weight: 572.60. Catalog: APB1185883402. | |
| Ezetimibe Impurity 64 | Ezetimibe Impurity 64. Uses: For analytical and research use. Alternative Names: (3R,6S)-6-(4-fluorophenyl)-3-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)tetrahydro-2H-pyran-2-one. Molecular formula: C24H21F2NO3. Mole weight: 409.43. Catalog: APB05369. | |
| Ezetimibe Impurity 65 | Ezetimibe Impurity 65. Uses: For analytical and research use. Alternative Names: (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-ol. Molecular formula: C24H23F2NO3. Mole weight: 411.44. Catalog: APB05368. | |
| Ezetimibe Impurity 66 | Ezetimibe Impurity 66. Uses: For analytical and research use. Alternative Names: (3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)propyl)azetidin-2-one. CAS No. 204589-96-8. Molecular formula: C31H27F2NO2. Mole weight: 483.55. Catalog: APB204589968. | |
| Ezetimibe Impurity 8 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L42) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (S)-1-(4-fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione. Grade: > 95%. CAS No. 189028-93-1. Molecular formula: C20H18FNO4. Mole weight: 355.37. | |
| Ezetimibe Impurity 8 Enantiomer | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L46) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4R-phenyl-2-oxazolidinone. Grade: > 95%. CAS No. 404874-93-7. Molecular formula: C20H18FNO4. Mole weight: 355.37. | |
| Ezetimibe Impurity 9 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L43) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (S)-3-((2R,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one; 3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl(amino)]][4-[trimethylsilyl]-oxy]phenyl]methyl]-1-oxo-5-[(trimethylsily)-oxy]pentyl]-4-phenyl-(4S)-2-oxazolidinone. Grade: > 95%. CAS No. 272778-12-8. Molecular formula: C39H46F2N2O5Si2. Mole weight: 716.98. | |
| Ezetimibe Impurity A | Ezetimibe Impurity A. Uses: For analytical and research use. Alternative Names: (3R,4S)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 191330-56-0. Molecular formula: C24H19F2NO3. Mole weight: 407.41. Catalog: APB191330560. | |
| Ezetimibe Impurity B | Ezetimibe Impurity B. Uses: For analytical and research use. Alternative Names: (2R,5S)-N,5-bis(4-fluorophenyl)-5-hydroxy-2-(4-hydroxybenzyl)pentanamide. CAS No. 1197811-72-5. Molecular formula: C24H23F2NO3. Mole weight: 411.44. Catalog: APB1197811725. | |
| Ezetimibe Impurity B | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L14) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: methyl 5-(4-fluorophenyl)-5-hydroxypentanoate. Grade: > 95%. CAS No. 870634-36-9. Molecular formula: C12H15FO3. Mole weight: 226.25. | |
| Ezetimibe Impurity C | Ezetimibe Impurity C. Uses: For analytical and research use. Alternative Names: (2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide. CAS No. 1296129-15-1. Molecular formula: C24H21F2NO3. Mole weight: 409.43. Catalog: APB1296129151. | |
| Ezetimibe Impurity D | Ezetimibe Impurity D. Uses: For analytical and research use. Alternative Names: (3R,4S)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 204589-58-2. Molecular formula: C24H21F2NO2. Mole weight: 393.43. Catalog: APB204589582. | |
| Ezetimibe Impurity E | Ezetimibe Impurity E. Uses: For analytical and research use. Alternative Names: (3R,4S)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one. CAS No. 302781-98-2. Molecular formula: C24H22FNO3. Mole weight: 391.43. Catalog: APB302781982. | |
| Ezetimibe Impurity F | Ezetimibe Impurity F. Uses: For analytical and research use. Alternative Names: (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 190595-66-5. Molecular formula: C24H22FNO3. Mole weight: 391.43. Catalog: APB190595665. | |
| Ezetimibe Impurity G | Ezetimibe Impurity G. Uses: For analytical and research use. Alternative Names: (3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 1700622-06-5. Molecular formula: C24H21F2NO3. Mole weight: 409.43. Catalog: APB1700622065. | |
| Ezetimibe Impurity H | Ezetimibe Impurity H. Uses: For analytical and research use. Alternative Names: 1798008-25-9 (racemic); (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(2-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 2743547-96-6. Molecular formula: C24H21F2NO3. Mole weight: 409.43. Catalog: APB2743547966. | |
| Ezetimibe Impurity I | Ezetimibe Impurity I. Uses: For analytical and research use. Alternative Names: (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 1700622-07-6. Molecular formula: C25H24FNO3. Mole weight: 405.46. Catalog: APB1700622076. | |
| Ezetimibe Impurity J | Ezetimibe Impurity J. Uses: For analytical and research use. Alternative Names: (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 1700622-08-7. Molecular formula: C24H21ClFNO3. Mole weight: 425.88. Catalog: APB1700622087. | |
| Ezetimibe Impurity L | Ezetimibe Impurity L. Uses: For analytical and research use. Alternative Names: (R)-N,5-bis(4-fluorophenyl)-2-(4-hydroxybenzyl)pentanamide. CAS No. 1510820-22-0. Molecular formula: C24H23F2NO2. Mole weight: 395.44. Catalog: APB1510820220. | |
| Ezetimibe Impurity M | Ezetimibe Impurity M. Uses: For analytical and research use. Alternative Names: (S)-3-((S)-5-hydroxy-5-phenylpentanoyl)-4-phenyloxazolidin-2-one. Molecular formula: C20H21NO4. Mole weight: 339.39. Catalog: APB05462. | |
| Ezetimibe Impurity N | Ezetimibe Impurity N. Uses: For analytical and research use. Alternative Names: (R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one. CAS No. 404874-94-8. Molecular formula: C20H20FNO4. Mole weight: 357.38. Catalog: APB404874948. | |
| Ezetimibe Impurity O | Ezetimibe Impurity O. Uses: For analytical and research use. Alternative Names: (R)-3-((R)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one. CAS No. 1612153-32-8. Molecular formula: C20H20FNO4. Mole weight: 357.38. Catalog: APB1612153328. | |
| Ezetimibe Impurity P | Ezetimibe Impurity P. Uses: For analytical and research use. Alternative Names: 5-(4-fluorophenyl)-5-oxopentanoic acid. CAS No. 149437-76-3. Molecular formula: C11H11FO3. Mole weight: 210.2. Catalog: APB149437763. | |
| Ezetimibe Impurity Q1 | Ezetimibe Impurity Q1. Uses: For analytical and research use. Alternative Names: (S)-3-((2R,5R)-5-(4-fluorophenyl)-5-hydroxy-2-((S)-hydroxy(4-hydroxyphenyl)methyl)pentanoyl)-4-phenyloxazolidin-2-one. Molecular formula: C27H26FNO6. Mole weight: 479.5. Catalog: APB05460. | |
| Ezetimibe Impurity Q2 | Ezetimibe Impurity Q2. Uses: For analytical and research use. Alternative Names: (S)-3-((2R,5R)-5-(4-fluorophenyl)-5-hydroxy-2-((R)-hydroxy(4-hydroxyphenyl)methyl)pentanoyl)-4-phenyloxazolidin-2-one. Molecular formula: C27H26FNO6. Mole weight: 479.5. Catalog: APB05461. | |
| Ezetimibe Impurity R | Ezetimibe Impurity R. Uses: For analytical and research use. Alternative Names: (S)-3-((R,E)-5-(4-fluorophenyl)-5-hydroxy-2-(4-hydroxybenzylidene)pentanoyl)-4-phenyloxazolidin-2-one. Molecular formula: C27H24FNO5. Mole weight: 461.48. Catalog: APB05459. | |
| Ezetimibe Impurity S | Ezetimibe Impurity S. Uses: For analytical and research use. Alternative Names: (S)-3-((R)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one. CAS No. 528565-93-7. Molecular formula: C20H20FNO4. Mole weight: 357.38. Catalog: APB528565937. | |
| Ezetimibe Impurity (Tetrahydro-pyran-2-one) | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L35) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,6R)-6-(4-fluorophenyl)-3-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)tetrahydro-2H-pyran-2-one. Grade: > 95%. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezetimibe ketone | Ezetimibe, a compound known as a Niemann-Pick C1-like1 (NPC1L1) inhibitor and a potent Nrf2 activator, effectively inhibits cholesterol absorption. Additionally, Ezetimibe ketone (EZM-K) represents a phase-I metabolite of Ezetimibe. Category: Active pharmaceutical ingredients. Synonyms: EZM-K. CAS No. 191330-56-0. Product ID: API191330560. Molecular formula: C24H19F2NO3. Mole weight: 407.41. |  |
| Ezetimibe ketone | Ezetimibe ketone. Group: Biochemicals. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone; EZM-K. Grades: Highly Purified. CAS No. 191330-56-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C24H19F2NO3. US Biological Life Sciences. |  Worldwide |
| Ezetimibe ketone | Ezetimibe ketone. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 191330-56-0. Purity: 0.9851. Product ID: ALC-FP-191330560. Molecular formula: C24H19F2NO3. Mole weight: 407.41. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Ezetimibe ketone | Ezetimibe ketone is an orall active Nrf2 activator and ROS inhibitor. Ezetimibe ketone attenuates H2O2-induced reactive oxygen species production and reduces H2O2-induced apoptosis in renal tubular epithelial cells. Ezetimibe ketone suppresses renal tubular injury and inflammation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EZM-K. CAS No. 191330-56-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-133114. |  |
| Ezetimibe Ketone | A metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one; (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone; EZM-K; Ezetimibe 3-Oxo Impurity; 2-Azetidinone, 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-, (3R-trans)-. Grade: >95%. CAS No. 191330-56-0. Molecular formula: C24H19F2NO3. Mole weight: 407.42. | |
| Ezetimibe Lactam Cleaved Alcohol | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L23) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3'-Anhydro Ezetimibe Alcohol Impurity; (βR,γS)-γ-[(4-Fluorophenyl)amino]-β-[3-(4-fluorophenyl)-2-propen-1-yl]-4-hydroxybenzenepropanol. Grade: > 95%. CAS No. 1374250-07-3. Molecular formula: C24H23F2NO2. Mole weight: 395.45. | |
| Ezetimibe-[N-(4-fluorophenyl-d4)] | Ezetimibe-[N-(4-fluorophenyl-d4)] is the labelled analogue of Ezetimibe, which is a cholesterol absorption inhibitor. Synonyms: Ezetimibe-d4 [N-(4-fluorophenyl-d4)]; Ezetimibe-d4; Ezetimibe D4 (Fluoroaniline-d4); (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone-d4; (3R,4S)-1-(4-fluorophenyl-2,3,5,6-d4)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grade: ≥95%. CAS No. 1093659-90-5. Molecular formula: C24H17D4F2NO3. Mole weight: 413.45. | |
| Ezetimibe phenoxy glucuronide | Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe, demonstrating antihyperlipoproteinemic activity. Category: Active pharmaceutical ingredients. Synonyms: Ezetimibe β-D-glucuronide,Ezetimibe glucuronide. CAS No. 190448-57-8. Product ID: API190448578. Molecular formula: C30H29F2NO9. Mole weight: 585.55. | |
| Ezetimibe phenoxy glucuronide | A metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 4-[(2S,3R)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-2-azetidinyl]phenyl β-D-glucopyranosiduronic acid; Ezetimibe glucuronide; Sch 58235 glucuronide; Sch 60663; Ezetimibe β-D-Glucuronide; Ezetimibe phenoxy-β-D-glucuronide. Grade: >95%. CAS No. 190448-57-8. Molecular formula: C30H29F2NO9. Mole weight: 585.55. | |
| Ezetimibe phenoxy glucuronide | Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ezetimibe glucuronide; Ezetimibe β-D-glucuronide. CAS No. 190448-57-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-135391. | |
| Ezetimibe Phenoxy Glucuronide-[d4] | Ezetimibe Phenoxy Glucuronide-[d4] is the labelled analogue of Ezetimibe Phenoxy Glucuronide, which is a metabolite of Ezetimibe. Ezetimibe is a medication used to treat high blood cholesterol and certain other lipid abnormalities. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe D4 Phenoxy Glucuronide. Grade: 95% by HPLC; 98% atom D. CAS No. 1426174-41-5. Molecular formula: C30H25D4F2NO9. Mole weight: 589.57. | |
| Ezetimibe Phenoxy tert-Butyldiphenylsilyl Ether | Ezetimibe Phenoxy tert-butyldiphenylsilyl ether is a substituted Ezetimibe. Group: Biochemicals. Alternative Names: (3R, 4S) -1- (4-Fluorophenyl ) -3- [ (3S) -3- (4-fluorophenyl ) -3- hydroxypropyl ] -4- (4-tert-butyl diphenyl silyl oxyphenyl ) -2-azetidinone. Grades: Highly Purified. CAS No. 1042722-66-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ezetimibe Related Impurity 6 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L40) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-1-(3-fluorophenyl)-3-((S)-3-(3-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grade: > 95%. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezetimibe Related Impurity 7 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L41) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-1-(3-fluorophenyl)-3-((E)-3-(3-fluorophenyl)allyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grade: > 95%. CAS No. 204589-68-4. Molecular formula: C24H19F2NO2. Mole weight: 391.42. | |
| Ezetimibe Ring-Open Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L15) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 2-(4-Hydroxybenzyl)-N,5-bis-(4-fluorophenyl)-5-hydroxypentanamide. Grade: > 95%. CAS No. 1197811-72-5. Molecular formula: C24H23FNO3. Mole weight: 411.45. | |
| Ezetimibe ring-opening dehydrate impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L31) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (αR,βS)-β-[(4-Fluorophenyl)amino]-α-[3-(4-fluorophenyl)-2-propen-1-yl]-4-hydroxybenzenepropanoic Acid. Grade: > 95%. CAS No. 1292292-63-7. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezetimibe (Standard) | Ezetimibe (Standard) is the analytical standard of Ezetimibe. This product is intended for research and analytical applications. Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SCH 58235 (Standard). CAS No. 163222-33-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17376R. | |
| Ezetimibe tetrahydropyran analog | An impurity of Ezetimibe. Ezetimibe is a cholesterol absorption inhibitor used to reduce low-density lipoprotein (LDL) cholesterol levels in the blood. It is commonly used alone or in combination with other cholesterol-lowering medications, such as statins, to manage hypercholesterolemia and related conditions. Synonyms: N,6-Bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide; Ezetimibe Tetrahydropyran Impurity; Ezetimibe THP analog; Ezetimibe Cyclized Impurity; Ezetimibe Cyclic ether; Ezetimibe Cyclic Ether Impurity; N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxamide. Grade: ≥95%. CAS No. 1050631-82-7. Molecular formula: C24H21F2NO3. Mole weight: 409.43. | |
| Ezetimibe Triol Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L48) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R,5R)-3-(4-fluorophenyl)-5-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-((S)-2-hydroxy-1-phenylethyl)-4-(4-hydroxyphenyl)piperidine-2,6-dione. Grade: > 95%. Molecular formula: C33H30F2N2OS. Mole weight: 572.61. | |
| Ezh2 Antibody [M10N8] | Ezh2,KMT6 / EZH2. Group: Antibodies. Alternative Names: Ezh2,KMT6 / EZH2. Pack Sizes: 20ul. Product ID: F0281. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| EZH2-IN-14 | EZH2-IN-14 is a selective EZH2 (Histone Methyltransferase) inhibitor with an IC50 of 12 nM. EZH2-IN-14 inhibits the methyltransferase activity of EZH2/PRC2 (that is, reducing H3K27me3). EZH2-IN-14 shows >200-fold selective for EZH2 over the highly homologous H3K27 methyltransferase EZH1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1979157-17-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148458. | |
| EZH2-IN-15 | EZH2-IN-15 is a EZH2 inhibitor. EZH2-IN-15 has anti-tumor activity, and can be used for research of H3K27me3-dependent tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2098545-98-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153191. | |
| EZH2-IN-17 | EZH2-IN-17 (compound 28) is a potent and orally active EZH2 inhibitor with an IC50 value of 0.95 nM. EZH2-IN-17 exhibits high anti-proliferation activity against different lymphoma cell lines including WSU-DLCL2, Pfeiffer and Karpas-422 (IC50 values of 2.36 nM, 1.73 nM, and 1.82 nM, respectively)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2489672-09-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-149726. | |
| EZH2-IN-2 | EZH2-IN-2 (Example 69) is a EZH2 inhibitor with an IC50 and a TR-FRET IC50 of 64 nM and 20 nM. EZH2-IN-2 can be used for the research of cancer or precancerous condition related to EZH2 activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2238821-31-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0298. | |
| EZH2-IN-5 | EZH2-IN-5 is a potent inhibitor of EZH2 with IC50s of 1.52 and 4.07 nM for wild-type and mutant Tyr641 EZH2, respectively. Synonyms: Benzamide, 5-bromo-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-[[trans-4-(dimethylamino)cyclohexyl]ethylamino]-2-methyl-. CAS No. 1403258-69-4. Molecular formula: C26H37BrN4O2. Mole weight: 517.50. | |
| EZH2-IN-6 | EZH2-IN-6, an inhibitor of EZH2, has enhanced antitumor activity. Synonyms: 1H-Pyrrolo[2,3-b]pyridine-3-carboxamide, 1-[(1R)-1-[trans-4-[3-(cyclopropyloxy)-1-azetidinyl]cyclohexyl]ethyl]-N-[[1,2-dihydro-6-methyl-4-(methylthio)-2-oxo-3-pyridinyl]methyl]-2-methyl-. CAS No. 2702269-27-8. Molecular formula: C31H41N5O3S. Mole weight: 563.75. | |
| EZ HDL CHOLESTEROL KIT | EZ HDL CHOLESTEROL KIT. Product ID: ACMA00005204. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Ezlopitant | Ezlopitant, also known as CJ-11,974, is a NK1 receptor antagonist. It has antiemetic and antinociceptive effects. Synonyms: CJ 11,974; CJ-11974; CJ11974; (7S,8S)-7-[di(phenyl)methyl]-N-[(2-methoxy-5-propan-2-ylphenyl)methyl]-1-azabicyclo[2.2.2]octan-8-amine. CAS No. 147116-64-1. Molecular formula: C31H38N2O. Mole weight: 454.66. | |
| EZM0414 | EZM0414 is a first-in-class and oral SETD2 inhibitor, which is under research for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). Synonyms: EZM0414; 2411748-50-8; KCY37T9RXU; EZM-0414; UNII-KCY37T9RXU; N-[(1R,3S)-3-(4-acetylpiperazin-1-yl)cyclohexyl]-4-fluoro-7-methyl-1H-indole-2-carboxamide; 1H-Indole-2-carboxamide, N-((1R,3S)-3-(4-acetyl-1-piperazinyl)cyclohexyl)-4-fluoro-7-methyl-; N-((1R,3S)-3-(4-Acetylpiperazin-1-yl)cyclohexyl)-4-fluoro-7-methyl-1H-indole-2-carboxamide; CHEMBL5095235; SCHEMBL21739955; GLXC-25885; BDBM50594406; NSC841441; AKOS040760023; AT34570; NSC-841441; MS-26809; CS-0435622; KS6. Molecular formula: C22H29FN4O2. Mole weight: 400.49. | |
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