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| Product | Description | |
|---|---|---|
| Ezetimibe Azetidinone (Ring-opened Impurity) | A degradation product of the antihyperlipoproteinem ic Ezetimibe. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Ezetimibe Azetidinone Ring-opened Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L8) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe Azetidinone Ring-opened Sodium Salt Impurity (Technical Grade, >75%). Grade: > 95%. CAS No. 1391053-63-6. Molecular formula: C24H23F2NO4. Mole weight: 427.45. |  |
| Ezetimibe b-D-Glucuronide (Ezetimibe Phenoxy Glucuronide) | A metabolite of Ezetimibe, an antihyperlipoproteinem ic. A Cholesterol absorption inhibitor. Group: Biochemicals. Alternative Names: Ezetimibe Phenoxy Glucuronide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ezetimibe Benzyl Impurity (MBZT-2) | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L32) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-3-(3-(benzyloxy)-3-(4-fluorophenyl)propyl)-1-(3-fluorophenyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grade: > 95%. CAS No. 851860-29-2. Molecular formula: C31H27F2NO3. Mole weight: 499.56. | |
| Ezetimibe-d4 | Ezetimibe-d 4 is the deuterium labeled Ezetimibe. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: SCH 58235-d4. CAS No. 1093659-90-5. Pack Sizes: 1 mg. Product ID: HY-17376S. |  |
| Ezetimibe-[d4] | Ezetimibe-[d4] is the labelled analogue of Ezetimibe. Ezetimibe is a cholesterol absorption inhibitor. Synonyms: Ezetimibe D4; (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl-d4)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone; Sch-58235-d4. Grade: >98% by HPLC; >98% atom D. CAS No. 1093659-89-2. Molecular formula: C24H17D4F2NO3. Mole weight: 413.45. | |
| Ezetimibe-d4 ((3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone-d4) | Labeled Ezetimibe, an antihyperlipoproteinem ic. A Cholesterol absorption inhibitor. Group: Biochemicals. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ezetimibe-d4 β-D-Glucuronide | Phase-II labeled metabolite of Ezetimibe, an antihyperlipoproteinem ic. A cholesterol absorption inhibitor. Group: Biochemicals. Alternative Names: 4-[(2S,3R)-1-(4-Fluorophenyl-d4)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid; Ezetimibe-d4 Phenoxy Glucuronide; Sch 58235-d4 Glucuronide; Sch 60663-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ezetimibe-d4 Diacetate | A derivative of 2-azetidinone with antihyperlipoproteinem ic properties. Group: Biochemicals. Alternative Names: (3R,4S)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ezetimibe-d4 phenolic glucuronide | One of the isotope labelled impurities of Ezetimibe, which could be used as an antihyperlipoproteinemic agent. Synonyms: 4-[(2S,3R)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid-d4. Molecular formula: C30H25D4F2NO9. Mole weight: 589.58. | |
| Ezetimibe Dehydoxy Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L16) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3-Dehydroxy Ezetimibe; (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)propyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grade: > 95%. CAS No. 204589-58-2. Molecular formula: C24H21F2NO2. Mole weight: 393.44. | |
| Ezetimibe Deprotected Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L13) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (S)-3-((2R,5S)-5-(4-fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one. Grade: 95%. CAS No. 1185883-40-2. Molecular formula: C33H30F2N2O5. Mole weight: 572.61. | |
| Ezetimibe Desfluoro Chloro Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L29) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: N-Des(4-Fluorophenyl)-N-(3-chlorophenyl)-ezetimibe; (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grade: > 95%. Molecular formula: C24H21ClFNO3. Mole weight: 425.89. | |
| Ezetimibe Desfluoro Dehydoxy Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L45) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-3-((S)-3-(benzyloxy)-3-(4-fluorophenyl)propyl)-1-(3-fluorophenyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grade: > 95%. Molecular formula: C24H22FNO2. Mole weight: 375.45. | |
| Ezetimibe Desfluoro Methyl Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L30) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 4"DeFluoro-4"methyl-ezetimibe; (3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grade: > 95%. CAS No. 1700622-07-6. Molecular formula: C25H24FNO3. Mole weight: 405.47. | |
| Ezetimibe-D-glucuronide-[d4] | Ezetimibe-D-glucuronide-[d4] is an esteemed compound in the biomedical field, aiding in the research of hypercholesterolemia and familial hypercholesterolemia. Manifesting as a remarkable cholesterol absorption inhibitor, it deftly curtails cholesterol levels through the hindrance of intestinal cholesterol assimilation and associated phytosterol uptake. Synonyms: Ezetimibe-d4 β-D-Glucuronide; Ezetimibe-D-glucuronide D4. Molecular formula: C30H25D4F2NO9. Mole weight: 589.57. | |
| Ezetimibe Diacetate | Protected Ezetimibe derivative. Group: Biochemicals. Alternative Names: (3R,4S)-. Grades: Highly Purified. CAS No. 163380-20-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ezetimibe Diacetate | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L5) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-3-[(3S)-3-(Acetyloxy)-3-(4-fluorophenyl)propyl]-4-[4-(acetyloxy)phenyl]-1-(4-fluorophenyl)-2-azetidinone. Grade: > 95%. CAS No. 163380-20-9. Molecular formula: C28H25F2NO5. Mole weight: 493.51. | |
| Ezetimibe (Diacid Impurity) | An open-ringed diacid impurity of Ezetimibe. Group: Biochemicals. Alternative Names: (2R) -2- [ (S) - [ (4-Fluorophenyl) amino] [4- (phenylmethoxy) phenyl] methyl] pentanedioic Acid. Grades: Highly Purified. CAS No. 1013025-04-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ezetimibe Diacid Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: ((2R,3S)-2-[(4-Benzyloxyphenyl)-4-(4-Fluorophenylamino)methyl]pentanedioic acid). Grade: > 95%. CAS No. 1013025-04-1. Molecular formula: C25H24FNO5. Mole weight: 437.47. | |
| Ezetimibe diastereomers | An impurity of Ezetimibe. Ezetimibe is a selective cholesterol absorption inhibitor that targets the Niemann-Pick C1-Like 1 (NPC1L1) protein in the small intestine, blocking dietary and biliary cholesterol uptake. Synonyms: Ezetimibe R,R,R- and S,S,S-isomer; R,R,R-Ezetimibe and S,S,S-Ezetimibe; (3S,4S)-1-(4-Fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one and (3R,4R)-1-(4-Fluorophenyl)-3-[(R)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one; S,S,S-Ezetimibe and R,R,R-Ezetimibe. Grade: ≥95%. Molecular formula: C24H21F2NO3. Mole weight: 409.43. | |
| Ezetimibe Diol | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L22) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (1S,4R)-1-(4-Fluorophenyl)-4-[(S)-[(4-fluorophenyl)amino](4-hydroxyphenyl)methyl]-1,5-pentanediol. Grade: > 95%. CAS No. 1374250-08-4. Molecular formula: C24H25F2NO3. Mole weight: 413.47. | |
| Ezetimibe Fluoro Isomer | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L9) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-1-(4-Fluorophenyl)-3-[(S)-3-(2-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one; 2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-(2-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)-; (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(2-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone; Ezetimibe o-Fluorobenzene isomer; O-Fluorobenzene ezetimibe; Ezetimibe ortho-Fluorobenzene Isomer; 3'-(2-Fluorophenyl) Ezetimibe. Grade: ≥95%. CAS No. 2743547-96-6. Molecular formula: C24H21F2NO3. Mole weight: 409.43. | |
| Ezetimibe hydroxy-D-glucuronide-[d4] | Ezetimibe hydroxy-D-glucuronide-[d4] is a metabolite of stable isotope-labeled Ezetimibe, playing a profound role in illuminating the intricate mechanisms of Ezetimibe metabolism, pharmacokinetics and elimination pathways. Synonyms: Ezetimibe hydroxy-D-glucuronide D4. Molecular formula: C30H25D4F2NO9. Mole weight: 589.57. | |
| Ezetimibe Hydroxy Glucuronide | A metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe Hydroxy β-D-Glucuronide; (1S)-1-(4-Fluorophenyl)-3-[(2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxo-3-azetidinyl]propyl β-D-Glucopyranosiduronic Acid. Grade: > 95%. CAS No. 536709-33-8. Molecular formula: C30H29F2NO9. Mole weight: 585.55. | |
| Ezetimibe Hydroxy tert-Butyldiphenylsilyl Ether | Ezetimibe Hydroxy tert-butyldiphenylsilyl ether is a substituted Ezetimibe. Group: Biochemicals. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-tert-butyldiphenylsilyloxy-3-(4-fluorophenyl)propyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grades: Highly Purified. CAS No. 1217748-67-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ezetimibe Impuriry 66 | Ezetimibe Impuriry 66. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1044664-24-5. Molecular formula: C26H23F2NO4. Mole weight: 451.47. Catalog: APB1044664245. |  |
| Ezetimibe Impuriry 74 | Ezetimibe Impuriry 74. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1683564-73-9. Molecular formula: C31H27F2NO3. Mole weight: 499.56. Catalog: APB1683564739. | |
| Ezetimibe Impuriry 75 | Ezetimibe Impuriry 75. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1416263-36-9. Molecular formula: C31H27F2NO3. Mole weight: 499.56. Catalog: APB1416263369. | |
| Ezetimibe Impuriry 82 | Ezetimibe Impuriry 82. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1683564-75-1. Molecular formula: C31H27F2NO3. Mole weight: 499.56. Catalog: APB1683564751. | |
| Ezetimibe Impurity 10 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L44) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grade: > 95%. Molecular formula: C18H18FNO3. Mole weight: 315.35. | |
| Ezetimibe Impurity 2 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L17) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-oxo-3-phenylpropyl)azetidin-2-one. Grade: > 95%. Molecular formula: C31H26FNO3. Mole weight: 479.56. | |
| Ezetimibe Impurity 3 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L18) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-4-(4-(benzyloxy)phenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)-1-phenylazetidin-2-one. Grade: > 95%. Molecular formula: C31H26FNO3. Mole weight: 479.56. | |
| Ezetimibe impurity (3-[5-(4-Fluoro-phenyl)-5-(R)-hydroxy-pentanoyl]-4-(R)-phenyl-oxazolidin-2-one) | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L38) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (4R)-4-Phenyl-3-[(5R)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one. Grade: > 95%. Molecular formula: C20H20FNO4. Mole weight: 357.39. | |
| Ezetimibe impurity (3-[5-(4-Fluoro-phenyl)-5-(R)-hydroxy-pentanoyl]-4-(S)-phenyl-oxazolidin-2-one) | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L36) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (S)-3-((R)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one. Grade: > 95%. CAS No. 528565-93-7. Molecular formula: C20H20FNO4. Mole weight: 357.39. | |
| Ezetimibe impurity (3-[5-(4-Fluoro-phenyl)-5-(S)-hydroxy-pentanoyl]-4-(R)-phenyl-oxazolidin-2-one) | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L37) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (4R)-4-Phenyl-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one. Grade: > 95%. CAS No. 189028-95-3. Molecular formula: C20H20FNO4. Mole weight: 357.39. | |
| Ezetimibe impurity (3-[5-(4-Fluoro-phenyl)-5-(S)-hydroxy-pentanoyl]-4-(S)-phenyl-oxazolidin-2-one) | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L39) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (4S)-4-Phenyl-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one. Grade: > 95%. Molecular formula: C20H20FNO4. Mole weight: 357.39. | |
| Ezetimibe Impurity 38 | Ezetimibe Impurity 38. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-3-((2R,5S)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-(4-((tert-butyldimethylsilyl)oxy)phenyl)((4-fluorophenyl)amino)methyl)-5-(4-fluorophenyl)pentanoyl)-4-phenyloxazolidin-2-one. CAS No. 1701462-59-0. Molecular formula: C45H58F2N2O5Si2. Mole weight: 801.12. Catalog: APB1701462590. | |
| Ezetimibe Impurity 39 | Ezetimibe Impurity 39. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-hydroxybenzaldehyde. CAS No. 123-08-0. Molecular formula: C7H6O2. Mole weight: 122.12. Catalog: APB123080. | |
| Ezetimibe Impurity 4 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L19) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3S,4R)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one. Grade: > 95%. Molecular formula: C31H25F2NO3. Mole weight: 497.55. | |
| Ezetimibe Impurity 49 | Ezetimibe Impurity 49. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: dihydro-2H-pyran-2,6(3H)-dione. CAS No. 108-55-4. Molecular formula: C5H6O3. Mole weight: 114.1. Catalog: APB108554. | |
| Ezetimibe Impurity 5 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L20) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)azetidin-2-one. Grade: > 95%. Molecular formula: C31H27F2NO3. Mole weight: 499.56. | |
| Ezetimibe Impurity 8 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L42) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (S)-1-(4-fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione. Grade: > 95%. CAS No. 189028-93-1. Molecular formula: C20H18FNO4. Mole weight: 355.37. | |
| Ezetimibe Impurity 8 Enantiomer | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L46) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4R-phenyl-2-oxazolidinone. Grade: > 95%. CAS No. 404874-93-7. Molecular formula: C20H18FNO4. Mole weight: 355.37. | |
| Ezetimibe Impurity 9 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L43) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (S)-3-((2R,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one; 3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl(amino)]][4-[trimethylsilyl]-oxy]phenyl]methyl]-1-oxo-5-[(trimethylsily)-oxy]pentyl]-4-phenyl-(4S)-2-oxazolidinone. Grade: > 95%. CAS No. 272778-12-8. Molecular formula: C39H46F2N2O5Si2. Mole weight: 716.98. | |
| Ezetimibe Impurity B | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L14) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: methyl 5-(4-fluorophenyl)-5-hydroxypentanoate. Grade: > 95%. CAS No. 870634-36-9. Molecular formula: C12H15FO3. Mole weight: 226.25. | |
| Ezetimibe Impurity G | Ezetimibe Impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 1700622-06-5. Molecular formula: C24H21F2NO3. Mole weight: 409.43. Catalog: APB1700622065. | |
| Ezetimibe Impurity I | Ezetimibe Impurity I. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 1700622-07-6. Molecular formula: C25H24FNO3. Mole weight: 405.46. Catalog: APB1700622076. | |
| Ezetimibe Impurity J | Ezetimibe Impurity J. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 1700622-08-7. Molecular formula: C24H21ClFNO3. Mole weight: 425.88. Catalog: APB1700622087. | |
| Ezetimibe Impurity L | Ezetimibe Impurity L. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-N,5-bis(4-fluorophenyl)-2-(4-hydroxybenzyl)pentanamide. CAS No. 1510820-22-0. Molecular formula: C24H23F2NO2. Mole weight: 395.44. Catalog: APB1510820220. | |
| Ezetimibe Impurity (Tetrahydro-pyran-2-one) | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L35) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,6R)-6-(4-fluorophenyl)-3-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)tetrahydro-2H-pyran-2-one. Grade: > 95%. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezetimibe ketone | Ezetimibe ketone. Group: Biochemicals. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone; EZM-K. Grades: Highly Purified. CAS No. 191330-56-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C24H19F2NO3. US Biological Life Sciences. | Worldwide |
| Ezetimibe ketone | Ezetimibe ketone (EZM-K) is a phase-I metabolite of Ezetimibe. Ezetimibe is a Niemann-Pick C1-like1 ( NPC1L1 ) inhibitor, and is a potent Nrf2 activator. Ezetimibe is a potent cholesterol absorption inhibitor [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EZM-K. CAS No. 191330-56-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-133114. | |
| Ezetimibe Ketone | A metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one; (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone; EZM-K; Ezetimibe 3-Oxo Impurity; 2-Azetidinone, 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-, (3R-trans)-. Grade: >95%. CAS No. 191330-56-0. Molecular formula: C24H19F2NO3. Mole weight: 407.42. | |
| Ezetimibe Lactam Cleaved Alcohol | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L23) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3'-Anhydro Ezetimibe Alcohol Impurity; (βR,γS)-γ-[(4-Fluorophenyl)amino]-β-[3-(4-fluorophenyl)-2-propen-1-yl]-4-hydroxybenzenepropanol. Grade: > 95%. CAS No. 1374250-07-3. Molecular formula: C24H23F2NO2. Mole weight: 395.45. | |
| Ezetimibe-[N-(4-fluorophenyl-d4)] | Ezetimibe-[N-(4-fluorophenyl-d4)] is the labelled analogue of Ezetimibe, which is a cholesterol absorption inhibitor. Synonyms: Ezetimibe-d4 [N-(4-fluorophenyl-d4)]; Ezetimibe-d4; Ezetimibe D4 (Fluoroaniline-d4); (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone-d4; (3R,4S)-1-(4-fluorophenyl-2,3,5,6-d4)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grade: ≥95%. CAS No. 1093659-90-5. Molecular formula: C24H17D4F2NO3. Mole weight: 413.45. | |
| Ezetimibe phenoxy glucuronide | Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity [1]. Ezetimibe is a potent cholesterol absorption inhibitor [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ezetimibe glucuronide; Ezetimibe β-D-glucuronide. CAS No. 190448-57-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-135391. | |
| Ezetimibe phenoxy glucuronide | A metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 4-[(2S,3R)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-2-azetidinyl]phenyl β-D-glucopyranosiduronic acid; Ezetimibe glucuronide; Sch 58235 glucuronide; Sch 60663; Ezetimibe β-D-Glucuronide; Ezetimibe phenoxy-β-D-glucuronide. Grade: >95%. CAS No. 190448-57-8. Molecular formula: C30H29F2NO9. Mole weight: 585.55. | |
| Ezetimibe Phenoxy Glucuronide-[d4] | Ezetimibe Phenoxy Glucuronide-[d4] is the labelled analogue of Ezetimibe Phenoxy Glucuronide, which is a metabolite of Ezetimibe. Ezetimibe is a medication used to treat high blood cholesterol and certain other lipid abnormalities. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe D4 Phenoxy Glucuronide. Grade: 95% by HPLC; 98% atom D. CAS No. 1426174-41-5. Molecular formula: C30H25D4F2NO9. Mole weight: 589.57. | |
| Ezetimibe Phenoxy tert-Butyldiphenylsilyl Ether | Ezetimibe Phenoxy tert-butyldiphenylsilyl ether is a substituted Ezetimibe. Group: Biochemicals. Alternative Names: (3R, 4S) -1- (4-Fluorophenyl ) -3- [ (3S) -3- (4-fluorophenyl ) -3- hydroxypropyl ] -4- (4-tert-butyl diphenyl silyl oxyphenyl ) -2-azetidinone. Grades: Highly Purified. CAS No. 1042722-66-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ezetimibe Related Impurity 6 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L40) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-1-(3-fluorophenyl)-3-((S)-3-(3-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grade: > 95%. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezetimibe Related Impurity 7 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L41) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-1-(3-fluorophenyl)-3-((E)-3-(3-fluorophenyl)allyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grade: > 95%. CAS No. 204589-68-4. Molecular formula: C24H19F2NO2. Mole weight: 391.42. | |
| Ezetimibe Ring-Open Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L15) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 2-(4-Hydroxybenzyl)-N,5-bis-(4-fluorophenyl)-5-hydroxypentanamide. Grade: > 95%. CAS No. 1197811-72-5. Molecular formula: C24H23FNO3. Mole weight: 411.45. | |
| Ezetimibe ring-opening dehydrate impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L31) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (αR,βS)-β-[(4-Fluorophenyl)amino]-α-[3-(4-fluorophenyl)-2-propen-1-yl]-4-hydroxybenzenepropanoic Acid. Grade: > 95%. CAS No. 1292292-63-7. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezetimibe System Suitability Mixture | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Ezetimibe tetrahydropyran analog | An impurity of Ezetimibe. Ezetimibe is a cholesterol absorption inhibitor used to reduce low-density lipoprotein (LDL) cholesterol levels in the blood. It is commonly used alone or in combination with other cholesterol-lowering medications, such as statins, to manage hypercholesterolemia and related conditions. Synonyms: N,6-Bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide; Ezetimibe Tetrahydropyran Impurity; Ezetimibe THP analog; Ezetimibe Cyclized Impurity; Ezetimibe Cyclic ether; Ezetimibe Cyclic Ether Impurity; N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxamide. Grade: ≥95%. CAS No. 1050631-82-7. Molecular formula: C24H21F2NO3. Mole weight: 409.43. | |
| Ezetimibe Triol Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L48) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R,5R)-3-(4-fluorophenyl)-5-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-((S)-2-hydroxy-1-phenylethyl)-4-(4-hydroxyphenyl)piperidine-2,6-dione. Grade: > 95%. Molecular formula: C33H30F2N2OS. Mole weight: 572.61. | |
| EZH1/EED/SUZ12 human | recombinant, expressed in baculovirus infected insect cells. Group: Fluorescence/luminescence spectroscopy. | |
| EZH1/EED/SUZ12/RbAp48/AEBP2 human | recombinant, expressed in baculovirus infected insect cells, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| EZH2/EED inactive human | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
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