A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Evenamide is a selective voltage-gated sodium and?/or calcium channel modulator, including subtypes Nav1.3, Nav1.7, and Nav1.8. It may be potentia useful in preventing, alleviating and curing a wide range of pathologies, including neurol., cognitive, psychiatric, inflammatory, urogenital and gastrointestinal diseases. It has shown efficacy in animal models of psychosis, mania, depression, and aggression. It was under development by Newron Pharmaceuticals as an add-on therapy for the treatment of schizophrenia. It is in phase II clinical trials. Uses: Evenamide may be potentia useful in preventing, alleviating and curing a wide range of pathologies, including neurol., cognitive, psychiatric, inflammatory, urogenital and gastrointestinal diseases. it is used as an add-on therapy for the treatment of schizophrenia. Synonyms: 2-[2-(3-Butoxyphenyl)ethylamino]-N,N-dimethylacetamide; NW-3509; NW 3509; NW3509; NW-3509A; Evenamide. Grade: >98%. CAS No. 1092977-61-1. Molecular formula: C16H26N2O2. Mole weight: 278.40.
Evenamide
Evenamide (NW-3509) is an orally available voltage-gated sodium channel (VGSC) blocker (Ki=0.4 μM) for the research of schizophrenia. Evenamide shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NW-3509. CAS No. 1092977-61-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17612.
Evening primrose oil
Evening primrose oil. Alternative Names: Oenotherabiennisextractus. CAS No. 65546-85-2. Purity: 0.98. Product ID: CI-EO-0013. Alfa Chemistry - ISO 9001:32057 Certified.
Evening primrose oil microencapsulated powder
Evening primrose oil microencapsulated powder. Product ID: CDF4-0206. Molecular formula: NA. Category: Nutrient supplements. Product Keywords: Food Ingredients; Nutrients; CDF4-0206; Evening primrose oil microencapsulated powder; Nutrient supplements. Appearance: White to light yellow powder. Color: White to light yellow. Physical State: powder. Source and Preparation: evening primrose. Applications: Dietary supplements, nutritional supplements, cosmetic raw materials, etc.
Evernic acid is a secondary metabolite produced by some species of lichen. It is an inhibitor of two key plasmodial FAS-II enzymes PfFabZ and PfFabI (IC50 = 10.7 and 36.1 μM, respectively). Synonyms: NSC 81164; 2-hydroxy-4-(2-hydroxy-4-methoxy-6-methylbenzoyl)oxy-6-methylbenzoic acid. Grade: ≥98%. CAS No. 537-09-7. Molecular formula: C17H16O7. Mole weight: 332.3.
Evernimicin
Evernimicin is an antibiotic that belongs to the orthosomycin class of antimicrobial agents. It was initially derived from the fermentation products of the soil bacterium Micromonospora carbonacea. Evernimicin is effective against a broad range of Gram-positive bacteria, including multidrug-resistant strains. It has shown activity against pathogens such as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and Streptococcus pneumoniae. Synonyms: Ziracin; SCH 27899; SCH27899; SCH-27899; Flambamycin, 56-deacetyl-57-demethyl-45-O-de(2-methyl-1-oxopropyl)-12-O-(2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitro-α-L-arabino-hexopyranosyl)-, 56-(2,4-dihydroxy-6-methylbenzoate); O-(1R)-4-O-(2,4-Dihydroxy-6-methylbenzoyl)-2,3-O-methylene-D-xylopyranosylidene-(1→3-4)-α-L-lyxopyranosyl O-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitro-α-L-arabino-hexopyranosyl-(1→3)-O-2,6-dideoxy-4-O-(3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoyl)-β-D-arabino-hexopyranosyl-(1→4)-O-(1R)-2,6-dideoxy-D-arabino-hexopyranosylidene-(1→3-4)-O-6-deoxy-3-C-methyl-β-D-mannopyranosyl-(1→3)-O-6-deoxy-4-O-methyl-β-D-galactopyranosyl-(1→4)-2,6-di-O-methyl-β-D-mannopyranoside; Antibiotic 13-384-1; Everninomicin; Everninomicin 13384-1; Everninomycin; Sch 27899. Grade: 95%. CAS No. 109545-84-8. Molecular formula: C70H97Cl2NO38. Mole weight: 1631.41.
Everninomicin B is a carbohydrate antibiotic produced by Micromonospora carbonacea var. carbonacea. It has anti-gram-positive bacteria and mycobacterial activity. Synonyms: Everninomycin-B; R-451-B. CAS No. 53296-30-3. Molecular formula: C66H99Cl2NO36. Mole weight: 1553.38.
Everninomicin C
Everninomicin C is a carbohydrate antibiotic produced by Micromonospora carbonacea var. CAS No. 53296-29-0. Molecular formula: C63H93Cl2NO34. Mole weight: 1479.30.
Everninomicin D
Everninomicin D is a carbohydrate antibiotic produced by Micromonospora carbonacea var. carbonacea. It has anti-gram-positive bacteria and mycobacterial activity. Synonyms: Flambamycin, 57-demethyl-45-O-de(2-methyl-1-oxopropyl)-59-deoxo-23-deoxy-59-methoxy-45-O-methyl-12-O-(2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitro-alpha-L-arabino-hexopyranosyl)-, (59S)-. CAS No. 39340-46-0. Molecular formula: C66H99Cl2NO35. Mole weight: 1537.38.
Everolimus is an inhibitor of mammalian target of rapamycin (mTOR) with an immunosuppressive activity which is comparable to that of rapamycin. It inhibits cytokine-mediated lymphocyte proliferation. Everolimus can be used as an immunosuppressant in the treatment of renal cell cancer and other cancers. Uses: Immunosuppressant. Synonyms: RAD-001; RAD001; RAD 001; Afinitor; Certican; Zortress; RAD001; SDZ-RAD. Grade: >98%. CAS No. 159351-69-6. Molecular formula: C53H83NO14. Mole weight: 958.24.
Everolimus
Everolimus (RAD001) is a Rapamycin (HY-10219) derivative and a potent, selective, orally active, blood-brain barrier-permeable mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RAD001; SDZ-RAD. CAS No. 159351-69-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-10218.
Everolimus
Everolimus is an immunosuppressant analog of rapamycin (sirolimus) and inhibits growth factor-mediated proliferation of hematopoietic and nonhematopoietic cells. Everolimus shows a potent inhibitory effect on posttransplant lymphoproliferative disorder (PTLD)-derived cells in vitro and in vivo, in a dose range that can prevent allograft rejection, and may demonstrate activity in both the prevention and treatment of PTLDs in transplant patients. Group: Biochemicals. Alternative Names: Afinitor, Certican, RAD-001, Zortress; 40-O- (2-Hydroxyethyl) rapamycin; 42-O-(2-Hydroxy)ethyl Rapamycin; RAD; RAD 001; SDZ-RAD; XIENCE V. Grades: Highly Purified. CAS No. 159351-69-6. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
Macrolide immunosuppressant; derivative of Rapamycin. Inhibits cytokine-mediated lymphocyte proliferation. Group: Biochemicals. Alternative Names: 40-O-(2-Hydroxyethyl-d4)rapamycin; 42-O-(2-Hydroxy)ethyl-d4 Rapamycin; Afinitor-d4; Certican-d4; RAD-d4; RAD 001-d4; SDZ-RAD-d4; XIENCE V-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Everolimus-d4
Everolimus-d4 is the deuterium labeled Everolimus. Everolimus (RAD001) is a Rapamycin derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RAD001-d4; SDZ-RAD-d4. CAS No. 1338452-54-2. Pack Sizes: 500 μg; 1 mg. Product ID: HY-10218S.
Everolimus-[d4]
Everolimus-[d4] is the labelled analogue of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Everolimus D4; 40-O-(2-Hydroxyethyl-d4)rapamycin; 42-O-(2-Hydroxy)ethyl-d4 Rapamycin; Afinitor-d4; Certican-d4; RAD-d4; RAD 001-d4; SDZ-RAD-d4; XIENCE V-d4. Grade: 95% by HPLC; 95% atom D. CAS No. 1338452-54-2. Molecular formula: C53H79D4NO14. Mole weight: 962.25.
An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Synonyms: Everolimus 19-Ene Open-Ring Impurity; Everolimus Related Compound 2; seco Everolimus; (19E/Z)-seco-[4-O-(2-Hydroxyethyl)] Rapamycin. CAS No. 1062122-63-7. Molecular formula: C53H83NO14. Mole weight: 958.22.
Everolimus EP Impurity B
Everolimus EP Impurity B. Uses: For analytical and research use. CAS No. 1062122-63-7. Molecular formula: C53H83NO14. Mole weight: 958.24. Catalog: APB1062122637.
Everolimus EP Impurity B (19-Z-Isomer)
Everolimus EP Impurity B (19-Z-Isomer). Uses: For analytical and research use. CAS No. 763911-41-7. Molecular formula: C53H83NO14. Mole weight: 958.24. Catalog: APB763911417.
Everolimus EP Impurity C
Everolimus EP Impurity C. Uses: For analytical and research use. Molecular formula: C52H81NO14. Mole weight: 944.21. Catalog: APB07747.
Everolimus EP Impurity C
An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Synonyms: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18,19-trihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-30-methoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone; 19-O-demethyl everolimus. Molecular formula: C52H81NO14. Mole weight: 944.2.
Everolimus EP Impurity D
An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Synonyms: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1-hydroxy-18-(2-hydroxyethoxy)-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone; 18-O-hydroxyethyl sirolimus. Molecular formula: C53H83NO14. Mole weight: 958.22.
Everolimus EP Impurity D
Everolimus EP Impurity D. Uses: For analytical and research use. Molecular formula: C53H83NO14. Mole weight: 958.24. Catalog: APB07748.
Everolimus EP Impurity E
Everolimus EP Impurity E. Uses: For analytical and research use. Alternative Names: Everolimus EP Impurity E. CAS No. 1237826-25-3. Molecular formula: C52H79NO14. Mole weight: 942.18. Catalog: APB1237826253.
Everolimus EP Impurity E
An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Synonyms: (1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexylformate. CAS No. 1237826-25-3. Molecular formula: C52H79NO14. Mole weight: 942.18.
Everolimus EP Impurity F
An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Synonyms: (1R,9S,12S,15R,16E,18R,19S,20R,21R,23S,24S,25E,27Ξ,28E,30S,32S,35R)-27-ethoxy-1,18,20-trihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36,37-trioxa-4-azatetracyclo[30.3.1.120,24.04,9]heptatriaconta-16,25,28-triene-2,3,10,14-tetrone. Molecular formula: C55H89NO16. Mole weight: 1020.29.
Everolimus EP Impurity F
Everolimus EP Impurity F. Uses: For analytical and research use. Alternative Names: Everolimus EP Impurity F. Molecular formula: C55H89NO16. Mole weight: 1020.29. Catalog: APB05420.
Everolimus Hydrolized Impurity
An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: seco Everolimus B; (2S)-1-[2-[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,20S,21R)-14,20-Dihydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15-docosatetraen-1-yl]tetrahydro-. Grade: > 95%. CAS No. 769905-89-7. Molecular formula: C53H85NO15. Mole weight: 976.27.
Everolimus Impurity 003-09
Everolimus Impurity 003-09. Uses: For analytical and research use. Alternative Names: Everolimus Impurity 003-09. Molecular formula: C107H167N2O28. Mole weight: 1929.47. Catalog: APB05415.
Everolimus Impurity 005-98
Everolimus Impurity 005-98. Uses: For analytical and research use. Alternative Names: (1R,9S,12S,15R,16Z,18R,19R,21R,23S,24Z,26Z,28Z,30S,32S,35R)-1,18,30-Trihydroxy-12-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2-propanyl}-19-methoxy-15,17,21,23,29,35-hexamethyl-11,36 ; -dioxa-4-azatricyclo[30.3.1.0]hexatriaconta-16,24,26. CAS No. 745779-75-3. Molecular formula: C52H81NO14. Mole weight: 944.2. Catalog: APB745779753.
Everolimus Impurity 008-96
Everolimus Impurity 008-96. Uses: For analytical and research use. Alternative Names: Everolimus Impurity 008-96. Molecular formula: C54H85NO14. Mole weight: 972.25. Catalog: APB02224.
Everolimus Impurity 012-99
Everolimus Impurity 012-99. Uses: For analytical and research use. Alternative Names: (S)-(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-2,6,8-trimethyl-5,9-dioxonon-7-en-3-yl 1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2. CAS No. 1708118-13-1. Molecular formula: C53H83NO14. Mole weight: 958.22. Catalog: APB1708118131.
Everolimus Impurity 013-99
Everolimus Impurity 013-99. Uses: For analytical and research use. Alternative Names: (S)-1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic acid. CAS No. 147438-30-0. Molecular formula: C32H49NO9. Mole weight: 591.73. Catalog: APB147438300.
Everolimus Impurity 11
Everolimus Impurity 11. Uses: For analytical and research use. Alternative Names: 2-((tert-butyldimethylsilyl)oxy)ethyl trifluoromethanesulfonate. Molecular formula: C9H19F3O4SSi. Mole weight: 308.39. Catalog: APB05419.
EverolimusImpurity12
EverolimusImpurity12. Uses: For analytical and research use. Alternative Names: Everolimus Impurity 12. Molecular formula: C55H87NO15. Mole weight: 1002.28. Catalog: APB05418.
Everolimus Impurity 13
Everolimus Impurity 13. Uses: For analytical and research use. Alternative Names: Everolimus Impurity 13. Molecular formula: C53H83NO14. Mole weight: 958.22. Catalog: APB05417.
Everolimus Impurity 14
Everolimus Impurity 14. Uses: For analytical and research use. Alternative Names: Everolimus Impurity 14. Molecular formula: C53H83NO14. Mole weight: 958.22. Catalog: APB05416.
Everolimus Impurity 16
Everolimus Impurity 16. Uses: For analytical and research use. Molecular formula: C53H83NO14. Mole weight: 958.22. Catalog: APB02225.
Everolimus Impurity 211-97
Everolimus Impurity 211-97. Uses: For analytical and research use. Alternative Names: Everolimus Impurity 211-97. Molecular formula: C52H81NO14. Mole weight: 944.2. Catalog: APB05422.
Everolimus Impurity 23 (Everolimus-13C2-D4)
Everolimus Impurity 23 (Everolimus-13C2-D4). Uses: For analytical and research use. CAS No. 1661009-29-5. Molecular formula: C5113C2H79D4NO14. Mole weight: 964.25. Catalog: APB1661009295.
Everolimus Impurity 24 (Everolimus-D4)
Everolimus Impurity 24 (Everolimus-D4). Uses: For analytical and research use. CAS No. 1338452-54-2. Molecular formula: C53H79D4NO14. Mole weight: 962.26. Catalog: APB1338452542.
Everolimus Impurity 25
Everolimus Impurity 25. Uses: For analytical and research use. Molecular formula: C53H83NO14. Mole weight: 958.24. Catalog: APB07749.
Everolimus Impurity 26
Everolimus Impurity 26. Uses: For analytical and research use. Molecular formula: C32H49NO9. Mole weight: 591.74. Catalog: APB07750.
Everolimus Impurity 27
Everolimus Impurity 27. Uses: For analytical and research use. Molecular formula: C54H85NO14. Mole weight: 972.27. Catalog: APB07751.
Everolimus Impurity 28
Everolimus Impurity 28. Uses: For analytical and research use. Molecular formula: C54H85NO14. Mole weight: 972.27. Catalog: APB07752.
Everolimus Impurity 501-95
Everolimus Impurity 501-95. Uses: For analytical and research use. Alternative Names: Everolimus Impurity 501-95. Molecular formula: C53H83NO14. Mole weight: 958.22. Catalog: APB05421.
Everolimus Impurity 6
Everolimus Impurity 6. Uses: For analytical and research use. CAS No. 1704711-12-5. Molecular formula: C54H85NO14. Mole weight: 972.27. Catalog: APB1704711125.
Everolimus Impurity 7
Everolimus Impurity 7. Uses: For analytical and research use. CAS No. 2402744-97-0. Molecular formula: C53H83NO14. Mole weight: 958.24. Catalog: APB2402744970.
Everolimus Impurity 9-O-Hydroxyethyl sirolimus (009-96). Uses: For analytical and research use. Alternative Names: Everolimus Impurity 9-O-Hydroxyethyl sirolimus(009-96). Molecular formula: C53H83NO14. Mole weight: 958.22. Catalog: APB05424.
Everolimus Impurity Everolimus-19-ene open ring (804-95)
Everolimus Impurity Everolimus-19-ene open ring (804-95). Uses: For analytical and research use. Alternative Names: (S)-1-(2-((2R,3R,6S)-2-hydroxy-6-((2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19E,21R)-14-hydroxy-22-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15,19-pentaen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic acid. Molecular formula: C53H83NO14. Mole weight: 958.22. Catalog: APB05423.
Everolimus Isomer C
An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 9,14-Deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-42-O-(2-hydroxyethyl)-14-oxorapamycin. Grade: 80%. CAS No. 908340-97-6. Molecular formula: C53H83NO14. Mole weight: 958.25.
Everolimus O-Desmethyl Impurity (Mixture of Diastereomers)
An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: (2S)-1-[2-[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,20S,21R)-14,20-Dihydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15-docosatetraen-1-yl]tetrahydro-2-hydroxy-3-methyl-. Grade: > 95%. Molecular formula: C57H91NO16. Mole weight: 1046.36.
Everolimus Related Compound 5
An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Di-tert-butyl-4-methylene-2,5-cyclohexadienone; 2,6-Di-t-butyl-4-methylene-2,5-cyclohexadienone. Grade: > 95%. CAS No. 2607-52-5. Molecular formula: C15H22O. Mole weight: 218.34.
Everolimus Related Compound 5
Everolimus Related Compound 5. Uses: For analytical and research use. CAS No. 2607-52-5. Molecular formula: C15H22O. Mole weight: 218.34. Catalog: APB2607525.
Everolimus Ring-Opening Impurity
An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Everolimus Retroaldol Degradation Product. Grade: 90% (Mixture of isomers). CAS No. 1708118-13-1. Molecular formula: C53H83NO14. Mole weight: 958.25.
Evexomostat
Evexomostat is a methionine aminopeptidase 2 (MetAP2) inhibitor. Synonyms: poly({N-[(2RS)-2-hydroxypropyl]methacrylamide}-co-[N-methacryloylgly-cyl-L-phenylalanyl-L-leucyl-N1-(trans-4-{[({(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]-octan-6-yl}oxy)carbonyl]amino}cyclohexyl)glycinamide (~0.91:0.09 x)]); poly([N-(2-hydroxypropyl)methacrylamide]-co-{methacryloyl-Gly-Phe-Leu-Gly amide with O-[(trans-4-aminocyclohexyl)carbamoyl]fumagillol}). CAS No. 2416263-67-5. Molecular formula: [(C7H13NO2)n(C46H68N6O10)]m.
Evifacotrep
Evifacotrep is a short transient receptor potential channel 5 (TRPC5) antagonist. Synonyms: 4-chloro-5-{4-[4-fluoro-2-(trifluoromethyl)phenoxy]-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl}pyridazin-3(2H)-one. CAS No. 2413739-88-3. Molecular formula: C18H12ClF4N5O2. Mole weight: 441.77.
Evinacumab
Evinacumab is a humanized anti-ANGPTL3 monoclonal antibody. Evinacumab has the potential therapeutic activity against homozygous familial hypercholesterolemia. Synonyms: Evkeeza; REGN1500. CAS No. 1446419-85-7.
Evinacumab
Evinacumab (REGN1500) is a human anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: REGN1500. CAS No. 1446419-85-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99194.