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| Product | Description | |
|---|---|---|
| Eltrombopag Impurity 85 | Eltrombopag Impurity 85. Uses: For analytical and research use. Molecular formula: C26H25N5O4. Mole weight: 471.52. Catalog: APB07870. |  |
| Eltrombopag Impurity 86 | Eltrombopag Impurity 86. Uses: For analytical and research use. Molecular formula: C26H25N5O4. Mole weight: 471.52. Catalog: APB07871. | |
| Eltrombopag Impurity 87 | Eltrombopag Impurity 87. Uses: For analytical and research use. Molecular formula: C27H27N5O4. Mole weight: 485.54. Catalog: APB07766. | |
| Eltrombopag Impurity 88 | Eltrombopag Impurity 88. Uses: For analytical and research use. CAS No. 2587607-84-7. Molecular formula: C27H27N5O4. Mole weight: 485.54. Catalog: APB2587607847. | |
| Eltrombopag Impurity 9 (Hydrochloride) | Eltrombopag Impurity 9 (Hydrochloride). Uses: For analytical and research use. Alternative Names: 3'-amino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid hydrochloride. Molecular formula: C13H11NO3·HCl. Mole weight: 265.53. Catalog: APB05636. | |
| Eltrombopag Impurity C | Eltrombopag Impurity C. Uses: For analytical and research use. Molecular formula: C25H21N5O5. Mole weight: 471.47. Catalog: APB07760. | |
| Eltrombopag Methyl Ester | Eltrombopag Methyl Ester. Group: Biochemicals. Alternative Names: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 1246929-01-0. Pack Sizes: 5mg. Molecular Formula: C26H24N4O4, Molecular Weight: 456.49. US Biological Life Sciences. |  Worldwide |
| Eltrombopag Methyl Ester | Eltrombopag Methyl Ester is a metabolite of Eltrombopag. Synonyms: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxylic Acid Methyl Ester. Grade: > 95%. CAS No. 1246929-01-0. Molecular formula: C26H24N4O4. Mole weight: 456.49. |  |
| Eltrombopag N-Nitrosamine Impurity | Eltrombopag N-Nitrosamine Impurity. Uses: For analytical and research use. Alternative Names: (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-5'-nitroso-[1,1'-biphenyl]-3-carboxylic acid. Molecular formula: C25H21N5O5. Mole weight: 471.46. Catalog: APB05610. | |
| Eltrombopag Olamine | Eltrombopag is a is an agonist of the c-mpl (TpoR) receptor used as treatment for thrombocytopenia.It has been developed for certain conditions that lead to thrombocytopenia (abnormally low platelet counts). Uses: C-mpl agonist. Synonyms: SB-497115-GR; 2-mainoethan-1-ol hemi((Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate). Grade: ≥98%. CAS No. 496775-62-3. Molecular formula: C29H36N6O6. Mole weight: 564.64. | |
| Eltrombopag Olamine | Eltrombopag Olamine (Eltrombopag diethanolamine salt) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag Olamine owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag Olamine can be used for the research of cardiovascular. Eltrombopag Olamine also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag Olamine can induce apoptosis in hepatocellular carcinomab (HCC) as well[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Eltrombopag diethanolamine salt; SB-497115GR. CAS No. 496775-62-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15306A. |  |
| Eltrombopag Olamine | Eltrombopag Olamine. Uses: For analytical and research use. Alternative Names: (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid, 2-aminoethan-1-ol (1:2). CAS No. 496775-62-3. Molecular formula: C25H22N4O4· 2C2H7NO. Mole weight: 564.6. Catalog: APB496775623. | |
| Eltrombopag Olamine | Eltrombopag is a is an agonist of the c-mpl (TpoR) receptor used as treatment for thrombocytopenia.It has been developed for certain conditions that lead to thrombocytopenia (abnormally low platelet counts). Category: Other apis. Synonyms: Promacta. Revolade. UNII-4U07F515LG. CAS No. 496775-62-3. Product ID: API496775623. Molecular formula: C29H36N6O6. Mole weight: 564.6. SMILES: CC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)N=NC3=CC=CC(=C3O)C4=CC(=CC=C4)C(=O)O)C.C(CO)N.C(CO)N. Appearance: White solid powder. |  |
| Elubrixin | Elubrixin is a interleukin 8 inhibitor and CXCR2 selective antagonist. It is potentially useful for Inflammatory bowel disease therapies. It inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans. It may be an effective agent in neutrophil-predominant diseases. It was developed by GlaxoSmithKline and was in clinic phase 2 trials, but now it is terminated. Uses: Elubrixin is potentially useful for inflammatory bowel disease therapies. it may be an effective agent in neutrophil-predominant diseases. Synonyms: 1-(2-Chloro-3-fluorophenyl)-3-(4-chloro-2-hydroxy-3-piperazin-1-ylsulfonylphenyl)urea; SB-656933; SB656933; SB-656933-AAF; SB-656933-AAA; SB656933AAA; SB656933AAF; 1-(4-Chloro-2-hydroxy-3-(piperazin-1-ylsulfonyl)phenyl)-3-(2-chloro-3-fluorophenyl)urea. Grade: 98%. CAS No. 688763-64-6. Molecular formula: C17H17Cl2FN4O4S. Mole weight: 463.30. | |
| Elubrixin tosylate | Elubrixin tosylate, a potent, selective, competitive, reversible and orally active antagonist of CXCR2 and IL-8 receptor, inhibits neutrophil CD11b upregulation (IC50 = 260.7 nM) and shape change (IC50 = 310.5 nM). It has potential in the study of inflammatory diseases, such as inflammatory bowel disease and airway inflammation. Synonyms: SB-656933 tosylate; N-[4-Chloro-2-hydroxy-3-[(piperazin-1-yl)sulfonyl]phenyl]-N'-(2-chloro-3-fluorophenyl)urea p-toluenesulfonate; 1-(2-Chloro-3-fluorophenyl)-3-[4-chloro-2-hydroxy-3-(1-piperazinylsulfonyl)phenyl]urea 4-methylbenzenesulfonate (1:1); Urea, N-(2-chloro-3-fluorophenyl)-N'-[4-chloro-2-hydroxy-3-(1-piperazinylsulfonyl)phenyl]-, 4-methylbenzenesulfonate (1:1). Grade: ≥95%. CAS No. 960495-43-6. Molecular formula: C24H25Cl2FN4O7S2. Mole weight: 635.51. | |
| Elucaine | Elucaine is a muscarinic acetylcholine receptor antagonist. It has anti-ulcerative activity. Synonyms: Elucaina; Benzenemethanol, alpha-((diethylamino)methyl)-, benzoate (ester). CAS No. 25314-87-8. Molecular formula: C19H23NO2. Mole weight: 297.40. | |
| Eluent 3: 0.5M Na2CO3 | Eluent 3: 0.5M Na2CO3. Uses: For analytical and research use. Alternative Names: Carbonic Acid Disodium Salt, Carbonic Acid Sodium Salt, Calcined Soda, Sodium carbonate, Anhydrous, V 20N, Disodium Carbonate, Bisodium Carbonate, V Soda, Dense Ash, Snowlite 1. CAS No. 497-19-8. Molecular formula: CO3.2Na. Mole weight: 105.99. IUPAC Name: disodium;carbonate. Catalog: APS497198. | |
| Elunetirom | Elunetirom (MA-JD21 )is a TR-β selective CNS-penetrant TR-β agonist prodrug and can be used for study of major depressive disorder (MDD)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MA-JD21; ABX-002. CAS No. 2156649-32-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160207. | |
| Elunonavir | Elunonavir is an antiviral. Synonyms: dimethyl (3S,8S,9S,12S)-6-({4-[1-(difluoromethyl)-1H-pyrazol-3-yl]-2,6-difluorophenyl}methyl)-8-hydroxy-9-{[4-({2-[8-(oxetan-3-yl)-3,8-diazabicyclo[3.2.1]octan-3-yl]pyrimidin-5-yl}ethynyl)phenyl]methyl}-4,11-dioxo-3,12-bis(1,1,1-trifluoro-2-methylpropan-2-yl)-2,5,6,10,13-pentaazatetradecane-1,14-dioate; methyl ((5S,8S,9S,14S)-11-(4-(1-(difluoromethyl)-1H-pyrazol-3-yl)-2,6-difluorobenzyl)-16,16,16-trifluoro-9-hydroxy-15,15-dimethyl-8-(4-((2-(8-(oxetan-3-yl)-3,8-diazabicyclo[3.2.1]octan-3-yl)pyrimidin-5-yl)ethynyl)benzyl)-3,6,13-trioxo-5-(1,1,1-trifluoro-2-methylpropan-2-yl)-2-oxa-4,7,11,12-tetraazahexadecan-14-yl)carbamate. CAS No. 2242428-57-3. Molecular formula: C52H59F10N11O8. Mole weight: 1156.09. | |
| Eluvixtamab | Eluvixtamab (AMG-330) is a bispecific T-cell engager. Eluvixtamab binds to CD33 and CD3 on T cells, thereby promoting T cell-mediated cytotoxicity against CD33+ cells. Eluvixtamab can be used in the research of tumors such as relapsed/refractory acute myeloid leukemia[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMG-330. CAS No. 1679391-73-1. Pack Sizes: 100 μg; 250 μg; 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P99910. | |
| Elvitegravir | A novel inhibitor of human immunodeficiency virus type 1 integrase. Group: Biochemicals. Alternative Names: 6-[(3-Chloro-2-fluorophenyl)methyl]-1,4-dihydro-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-3-quinolinecarboxylic Acid; GS 9137; JTK 303. Grades: Highly Purified. CAS No. 697761-98-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Elvitegravir | Elvitegravir is an HIV-1 integrase strand transfer inhibitor (INSTI) for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively. Uses: Anti-retroviral agents. Synonyms: GS-9137; GS 9137; GS9137; JTK-303; JTK 303; JTK303; EVG; D06677; D 06677; D-06677. Grade: ≥98%. CAS No. 697761-98-1. Molecular formula: C23H23ClFNO5. Mole weight: 447.88. | |
| Elvitegravir | Elvitegravir (GS-9137; JTK-303; D06677) is an HIV integrase inhibitor for HIV-1IIIB, HIV-2EHO and HIV-2ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS-9137; JTK-303; D06677. CAS No. 697761-98-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14740. | |
| Elvitegravir-[d5] | Elvitegravir-[d5] is the labelled analogue of Elvitegravir, which is a novel inhibitor of human immunodeficiency virus type 1 integrase. Synonyms: Elvitegravir D5; (S)-6-(3-chloro-2-fluorobenzyl)-1-(1-hydroxy-3-methylbutan-2-yl-1,1-d2)-7-(methoxy-d3)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 6-[(3-Chloro-2-fluorophenyl)methyl]-1,4-dihydro-1-[(1S)-1-(hydroxymethyl-d2)-2-methylpropyl]-7-(methoxy-d3)-4-oxo-3-quinolinecarboxylic Acid. Grade: 95%. CAS No. 1131640-69-1. Molecular formula: C23H18D5ClFNO5. Mole weight: 452.92. | |
| Elvitegravir Impurity 1 | Elvitegravir Impurity 1. Uses: For analytical and research use. Molecular formula: C24H24ClF3N2O5. Mole weight: 512.91. Catalog: APB12185. | |
| Elzasonan | Elzasonan is a selective 5-hydroxytryptamine 1B receptor antagonist that was developed by Pfizer (and then later discontinued in 2008) to treat patients with major depressive disorder and obsessive compulsive disorder. Group: Biochemicals. Grades: Highly Purified. CAS No. 361343-19-3. Pack Sizes: 50mg, 500mg. Molecular Formula: C22H23Cl2N3OS, Molecular Weight: 448.41. US Biological Life Sciences. | Worldwide |
| Elzasonan citrate | Elzasonan citrate is a selective 5-hydroxytryptamine 1B receptor antagonist for treat patients with major depressive disorder and obsessive compulsive disorder. Uses: Serotonin 1b receptor antagonists; serotonin 1d receptor antagonists. Synonyms: (2Z)-4-(3,4-dichlorophenyl)-2-[[2-(4-methylpiperazin-1-yl)phenyl]methylidene]thiomorpholin-3-one; 2-hydroxypropane-1,2,3-tricarboxylic acid. Grade: ≥98%. CAS No. 361343-20-6. Molecular formula: C28H31Cl2N3O8S. Mole weight: 640.53. | |
| Elzasonan hydrochloride | Elzasonan, also called as CP 448187, exhibits potent and selective antagonism of 5-HT1B receptors in vitro, and preclinical in vivo studies demonstrate enhanced 5-HT neurotransmission. Elzasonan is able to improve signaling to limbic regions like the hippocampus and prefrontal cortex and ultimately resulting in antidepressant effects. Synonyms: (2Z)-4-(3,4-dichlorophenyl)-2-[[2-(4-methylpiperazin-1-yl)phenyl]methylidene]thiomorpholin-3-one; hydrochloride; Elzasonan hydrochloride; Elzasonan HCl; UNII-X38F62RR8L. Grade: >98%. CAS No. 220322-05-4. Molecular formula: C22H24Cl3N3OS. Mole weight: 484.86. | |
| Elzovantinib | Elzovantinib is a potent and orally available inhibitor of MET, CSF1R (colony stimulating factor 1 receptor) and SRC kinases. The simultaneous inhibition of MET, SRC and CSF1R kinases is a promising strategy for the treatment of MET-driven solid tumors. Synonyms: CSF1R-IN-2; TPX-0022. CAS No. 2271119-26-5. Molecular formula: C20H20FN7O2. Mole weight: 409.42. | |
| Elzovantinib | Elzovantinib (TPX-0022) is an oral-active inhibitor of SRC, MET and c-FMS, with IC50 values of 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TPX-0022; CSF1R-IN-2. CAS No. 2271119-26-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111787. | |
| EM12-FS | EM12-FS is a cereblon (CRBN) ligand that binds CRBN at His353 and a molecular glue degrader of NTAQ1. EM12-FS has a human plasma half-life of 196 min[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2839138-44-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164891. | |
| EM12-SO2F | EM12-SO2F is a powerful covalent inhibitor of CRBN through binding at His353. EM12-SO2F is a useful chemical probe to investigate the CRBN. EM12-SO2F inhibits the degradation of IKZF1 by lenalidomide (HY-A0003) in MOLT4 cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2803819-61-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W760183. | |
| EM2487 | EM2487 is produced by the strain of Streptomyces sp. Mer-2487. It inhibited HLV-1 replication in both chronically and acutely infected cells. The action occurs during the post-integration phase of the HIV-1 provirus DNA in the HIV-1 replication cycle. Molecular formula: C32H57N5O16P2. Mole weight: 829.76. | |
| EM574 | Shows strong gastrointestinal motor stimulating (GMS) activity. Motilin receptor agonist. Stimulates smooth muscle cell contraction. Stimulates cholinergic neurons in a non-vagal pathway. Enhances gastrointestinal contractile activity and accelerates gastric emptying. Shows orexigenic activity with affinity for the growth-hormone secretagogue receptor (GHS-R, ghrelin receptor). Group: Biochemicals. Grades: Highly Purified. CAS No. 110480-13-2. Pack Sizes: 250ug, 1mg. Molecular Formula: C39H69NO12. US Biological Life Sciences. | Worldwide |
| EM574 | EM574 is an agonist of motilin receptor with an IC50 value of 6.17 nM which binds to rabbit gastric antral smooth muscle homogenates in a radioligand binding assay. Synonyms: Idremcinal; 8,9-didehydro-N-demethyl-9-deoxo-6-deoxy-6,9-epoxy-N-(1-methylethyl)-erythromycin. Grade: ≥98%. CAS No. 110480-13-2. Molecular formula: C39H69NO12. Mole weight: 743.96. | |
| EM-651 | EM-651 is the enantiomer form of EM-652 which is an orally active pure antiestrogen and selective estrogen receptor antagonist with IC50=0.44nM. Synonyms: 2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, (2R)-. CAS No. 182167-58-4. Molecular formula: C29H31NO4. Mole weight: 457.56. | |
| EMA401 | EMA401 is an orally bioavailable, potent and highly selective antagonist of the angiotensin II type 2 receptor (AT2; IC50s = 39.5 and 408,000 nM for rat recombinant AT2 and AT1, respectively). It inhibits capsaicin-induced calcium influx in cultured human dorsal root ganglion (hDRG) neurons (IC50 = 10 nM) and reduces neurite density and length in rat DRG neuronal cultures. Synonyms: EMA 401; EMA-401; Olodanrigan; (3S)-2-(2,2-diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-(phenylmethoxy)-3-isoquinolinecarboxylic acid. Grade: ≥ 95 %. CAS No. 1316755-16-4. Molecular formula: C32H29NO5. Mole weight: 507.6. | |
| Emactuzumab | Emactuzumab(RG 7155) is a specific monoclonal antibody that inhibits colonystimulating factor 1 receptor (CSF1R) activation. Emactuzumab has high affinity for CSF-1R with Ki value of 0.2 nM to blocks CSF-1R dimerization. Emactuzumab can be used for the research of several diseases, such as diffuse-type tenosynovial giant cell tumour (dt-GCT) [1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RG 7155; RO 5509554. CAS No. 1448221-67-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99245. | |
| e-Maleimidocaproic acid hydrazide trifluoroacetic acid 99+% (NMR) | e-Maleimidocaproic acid hydrazide trifluoroacetic acid 99+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Emamectin | Emamectin, also called as Proclaim, is widely used as an insecticide because of its chloride channel activation property. Synonyms: (4''R)-4''-Deoxy-4''-(methylamino)avermectin B1; emamectin B1a. CAS No. 119791-41-2. Molecular formula: C49H75NO13. Mole weight: 886.133. | |
| Emamectin B1a | It is a semi-synthetic 4''-epimethylamino analogue of avermectin B1a prepared by oxidation of the 4''-hydroxy moiety and reductive amination. It has strong insecticidal efficacy. Synonyms: L 656748; (4''R)-5-O-Demethyl-4''-deoxy-4''-(methylamino)avermectin A1a; 4''-Deoxy-4''-epi-(methylamino)avermectin B1a. Grade: >99% by HPLC. CAS No. 121124-29-6. Molecular formula: C49H75NO13. Mole weight: 886.12. | |
| Emamectin B1b | It is a semi-synthetic 4-epimethylamino analogue of avermectin B1b. It is prepared by oxidation of the 4-hydroxy moiety and reductive amination. It has strong insecticidal efficacy. Synonyms: Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-4''-deoxy-4''-(methylamino)-25-(1-methylethyl)-, (4''R)-. Grade: >99% by HPLC. CAS No. 121424-52-0. Molecular formula: C48H73NO13. Mole weight: 872.09. | |
| Emamectin Benzoate | Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-244. CAS No. 155569-91-8. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0837. | |
| Emamectin Benzoate | A mixture of semi-synthetic Avermectins. Exists as the anhydrous and various hydrated forms having different crystal morphologies. Insecticide. Group: Biochemicals. Alternative Names: 4''-Deoxy-4''-epi-N- (methylamino) avermectin B1 Benzoate; MK 244; Methylamino abamectin benzoate; Proclaim; Proclaim 5SG; Sch 58854; Shot-Wan; Slice. Grades: Highly Purified. CAS No. 155569-91-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Emamectin Benzoate | Emamectin Benzoate is the Emamectin derivative. Emamectin, also called as Proclaim, is widely used as an insecticide because of its chloride channel activation properties. Uses: Antiparasitic agents. Synonyms: Proclaim; Proclaim 5SG; Denim; Methylamino abamectin benzoate; Shot Wan; Denim (pesticide); Sch 58854; MK 244. Grade: 95.0% (sum of isomers, including Benzoate). CAS No. 155569-91-8. Molecular formula: C56H81NO15. Mole weight: 1008.24. | |
| Emapalumab | Emapalumab (NI-0501) is a human monoclonal IgG1 antibody that noncompetitively inhibits IFN-γ. Emapalumab binds with high affinity (Kd= 1.4 pM) to both free IFN-γ as well as IFN-γ bound to its receptor. Emapalumab can be used in research of hemophagocytic lymphohistiocytosis (HLH)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NI-0501. CAS No. 1709815-23-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P99191. | |
| Emapalumab | Emapalumab is an anti-interferon-gamma (IFNγ) monoclonal antibody approved for the treatment of primary hemophagocytic lymphohistiocytosis (HLH). Synonyms: Gamifant; NI-0501; NI 0501; NI0501. CAS No. 1709815-23-5. | |
| Emapunil | Emapunil (AC-5216), an orally active and selective TSPO (a mitochondrial benzodiazepine receptor) ligand, produces anti-anxiety and antidepressant-like effects in various animal models[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AC-5216; XBD-173. CAS No. 226954-04-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15527. | |
| Emapunil | Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively). Displays no noticeable binding to a number of other receptors, transporters or ion channels. Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects. Synonyms: AC-5216; AC 5216; AC5216; XBD-173; XBD 173; XBD173; Emapunil. Grade: >98%. CAS No. 226954-04-7. Molecular formula: C23H23N5O2. Mole weight: 401.46. | |
| Emavusertib | Emavusertib is an orally active inhibitor for IRAK4 (IC50=57 nM) and FLT3. Emavusertib inhibits NF-κB and MyD88 signaling pathways, reduces the generation of pro-inflammatory cytokines like IL-6 and IL-10, thereby exhibiting anti-inflammatory and anti-proliferative activities against cancer cells, leading to cell apoptosis. Emavusertib exhibits antitumor activity in mouse model. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CA-4948. CAS No. 1801344-14-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135317. | |
| Emavusertib | Emavusertib is an orally bioavailable inhibitor of interleukin-1 receptor-associated kinase 4/FMS-like Tyrosine Kinase 3 (IRAK4/FLT3). Synonyms: CA-4948; CA 4948; CA4948. CAS No. 1801344-14-8. Molecular formula: C24H25N7O5. Mole weight: 491.50. | |
| Embelin | Embelin is a natural benzoquinone found in plants of the Myrsinaceae family. Embelin has a wide range of biological activity as it inhibits the growth of bacteria, fungi, protozoa and parasites. Embelin also displays contraceptive and pro-apoptotic properties. Group: Biochemicals. Alternative Names: 2,5-Dihydroxy-3-undecyl-p-benzoquinone; 2,5-Dihydroxy-3-undecyl-1,4-benzoquinone; Embelic acid; Emberine; NSC 91874; 2,5-Dihydroxy-3-undecyl-2,5-cyclohexadiene-1,4-dione. Grades: Highly Purified. CAS No. 550-24-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Embelin | Embelin, a quinone isolated from the Japanese Ardisia herb, is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 uM. Synonyms: NSC91874; NSC91874; NSC 91874; Embelin; Emberine; Embelic acid. Grade: >98%. CAS No. 550-24-3. Molecular formula: C17H26O4. Mole weight: 294.39. | |
| Embelin | Embelin (Embelic acid), a potent, nonpeptidic XIAP inhibitor (IC50=4.1 μM), inhibits cell growth, induces apoptosis, and activates caspase-9 in prostate cancer cells with high levels of XIAP. Embelin blocks NF-kappaB signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. Embelin also induces autophagic and apoptotic cell death in human oral squamous cell carcinoma cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Embelic acid; Emberine; NSC 91874. CAS No. 550-24-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17473. | |
| EMBONIC ACID | EMBONIC ACID. CAS No. 130-85-8. Product ID: DS130858. Mole weight: 388.37. ECNumber: 204-998-0. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Embramine hydrochloride | Embramine hydrochloride. Alternative Names: embramine hydrochloride;2-[1-(4-Bromophenyl)-1-phenylethoxy]-N,N-dimethylethylamine hydrochloride;Mebrophenhydramine hydrochloride;Bromadryl. CAS No. 13977-28-1. Product ID: ACM13977281. Molecular formula: C18H23BrClNO. Mole weight: 384.73832. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Embusartan | Embusartan, an oxopyridine derivative, has been found to be an angiotensin II receptor antagonist that was once studied against hypertension by Bayer. Synonyms: Embusartan; UNII-4MY73645XA; Embusartan [INN]; Bay 10-6734; Bay-10-6734; methyl 2-butyl-1-[[2-fluoro-4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-6-oxopyridine-4-carboxylate. Grade: 98%. CAS No. 156001-18-2. Molecular formula: C25H24FN5O3. Mole weight: 461.49. | |
| EMCH | EMCH. Pack Sizes: Milligram Quantities: 50 mg. Order Number: CL224. |  www.prochemonline.com |
| EMD 281014 hydrochloride | EMD 281014 hydrochloride is a selective 5-HT2A antagonist with preference for human 5-HT2A over 5-HT2C receptors (Ki = 0.87 and 557 nM, respectively). EMD 281014 has the potential to treat insomnia. Uses: Potential treatment of insomnia. Synonyms: EMD 281014 hydrochloride; EMD281014 hydrochloride; EMD-281014 hydrochloride; Pruvanserin hydrochloride; Pruvanserin HCl; 7-[[4-[2-(4-Fluorophenyl)ethyl]-1-piperazinyl]carbonyl]-1H-indole-3-carbonitrile hydrochloride. Grade: ≥98% by HPLC. CAS No. 443144-27-2. Molecular formula: C22H21FN4O.HCl. Mole weight: 412.89. | |
| EMD 386088 | EMD 386088 is a potent 5-HT6 receptor partial agonist (Ki = 1 nM) used as an antidepressant. EMD-386088 is also a dopamine reuptake inhibitor. Synonyms: 1H-Indole, 5-chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-; 5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole; EMD-386088; EMD386088. Grade: ≥95%. CAS No. 54635-62-0. Molecular formula: C14H15ClN2. Mole weight: 246.74. | |
| EMD 386088 hydrochloride | EMD 386088 hydrochloride is a potent and selective 5-HT6 receptor agonist (EC50 = 1.0 nM) (IC50 = 7.4, 110, 180, 240, 450, 620, 660 and 3000 nM for 5-HT6, 5-HT1D, 5-HT1B, 5-HT2A, 5-HT2C, 5-HT4, 5-HT1A and 5-HT7 receptors, respectively) used as an antidepressant. Synonyms: 1H-Indole, 5-chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-, hydrochloride (1:1); EMD386088 hydrochloride; EMD-386088 hydrochloride; 5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole hydrochloride. Grade: ≥99% by HPLC. CAS No. 1171123-46-8. Molecular formula: C14H15N2Cl.HCl. Mole weight: 283.20. | |
| EMD 386088 hydrochloride | EMD 386088 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1171123-46-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| EMD527040 | EMD527040 is a potent and highly selective αvβ6 antagonist with antifibrotic activities. EMD527040 can be used for carcinoma and liver fibrosis research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 851333-14-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101473. | |
| EMD534085 | EMD534085 is a potent and selective mitotic kinesin-5 inhibitor with an IC50 of 8 nM. Synonyms: 1-(2-(Dimethylamino)ethyl)-3-(((2R,4aS,5R,10bS)-5-phenyl-9-(trifluoromethyl)-3,4,4a,5,6,10b-hexahydro-2H-pyrano(3,2-C)quinolin-2-yl)methyl)urea; EMD-534085; EMD 534085; N-[2-(Dimethylamino)ethyl]-N'-[[(2R,4aS,5R,10bS)-3,4,4a,5,6,10b-hexahydro-5-phenyl-9-(trifluoromethyl)-2H-pyrano[3,2-c]quinolin-2-yl]methyl]urea. Grade: ≥95%. CAS No. 858668-07-2. Molecular formula: C25H31F3N4O2. Mole weight: 476.53. | |
| EMD534085 | EMD534085 is a potent and selective inhibitor of the mitotic kinesin-5 with an IC50 of 8 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 858668-07-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15000. | |
| EMD 53998 | EMD 53998 is a cardiotonic agent that increases myocardial contractility as an inhibitor for phosphodiesterase III (PDE III) and a calcium sensitizer. EMD 53998 increases myocardial contractility, reduces energy consumption and the risk of inducing arrhythmias[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 120223-04-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-106844. | |
| EMD638683 | EMD638683 is an orally active SGK1 inhibitor with an IC50 of 3 μM. EMD638683 exhibits strong inhibition against SGK1, moderate inhibition against SGK2 and SGK3, and shows excellent selectivity for other AGC kinase family members. EMD638683 has antihypertensive activity by inhibiting SGK1, and independently of the blood pressure-lowering effect, it effectively prevents heart inflammation and fibrosis caused by hypertension by inhibiting the cardiac NLRP3 inflammation body/ IL-1β axis. EMD638683 promotes apoptosis of colon cancer cells and sensitizes radiotherapy. EMD638683 (S-Form) can be used in research related to hypertension, hypertensive heart damage, and colon cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1181770-72-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15193. | |
| EMD638683 | EMD638683 is a potent SGK1 inhibitor with an IC50 of 3 μM. Synonyms: EMD638683; EMD 638683; EMD-638683. Grade: >98%. CAS No. 1181770-72-8. Molecular formula: C18H18F2N2O4. Mole weight: 364.34. | |
| EMD638683 R-Form | EMD638683 (R-Form) is a SGK1 inhibitor with an IC50 of < 300 nM. Synonyms: EMD 638683 (R-Form); EMD638683 (R-Form); EMD-638683 (R-Form). Grade:>98%. CAS No. 1184940-47-3. Molecular formula: C18H18F2N2O4. Mole weight: 364.34. | |
| EMD638683 S-Form | EMD638683 (S-Form) is a SGK1 inhibitor with an IC50 of >300 nM. Synonyms: EMD 638683 (S-Form); EMD638683 (S-Form); EMD-638683 (S-Form). Grade: >98%. CAS No. 1184940-46-2. Molecular formula: C18H18F2N2O4. Mole weight: 364.34. | |
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