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| Product | Description | |
|---|---|---|
| Erinacine E | Erinacine E is a k opioid receptor agonist produced by Hericium ramosum CL24240. Synonyms: (-)-Erinacine E. Molecular formula: C25H36O6. Mole weight: 432.55. |  |
| Eriobrucinol methyl ether | Eriobrucinol methyl ether. Synonyms: 1H,7H-4,6-Dioxacyclobut[1,7]indeno[5,6-b]naphthalen-7-one, 1a,2,3,3a,10b,10c-hexahydro-10-methoxy-1,1,3a-trimethyl-, [1aR-(1aα,3aα,10bα,10cα)]-. CAS No. 42259-10-9. Molecular formula: C20H22O4. Mole weight: 326.39. | |
| Eriocalyxin B | Eriocalyxin B, isolated from the herbs of Isodon eriocalyx, is a potent NF-kappaB inhibitor. Eriocalyxin B inhibited the NF-kappaB transcriptional activity but not that of cAMP response element-binding protein. eriocalyxin B reversibly interfered with the binding of p65 and p50 subunits to the DNA in a noncompetitive manner. Eriocalyxin B exerts potent antiinflammatory effects through selective modulation of pathogenic Th1 and Th17 cells by targeting critical signaling pathways. Besides, Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways. Eriocalyxin B should be considered a candidate for pancreatic cancer treatment. Uses: Antiinflammatory. Synonyms: Rabdosianone. Grade: >98%. CAS No. 84745-95-9. Molecular formula: C20H24O5. Mole weight: 344.4. | |
| Eriochrome Black A | Eriochrome Black A. Group: Biochemicals. Alternative Names: 1-Naphthalene sulfonic acid. Grades: Highly Purified. CAS No. 3618-58-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences. |  Worldwide |
| Eriochrome Black T | Eriochrome Black T. Uses: For analytical and research use. Alternative Names: 1-(1-Hydroxy-2-naphthylazo)-6-nitro-2-naphthol-4-sulfonic Acid Sodium Salt; Mordant Black 11. CAS No. 1787-61-7. Molecular formula: C20H12N3NaO7S. Mole weight: 461.38. Catalog: APB1787617. |  |
| Eriochrome Black T (C.I. 14645) | 25g Pack Size. Group: Stains & Indicators. Formula: C20H12N3NaO7S. CAS No. 1787-61-7. Prepack ID 51499212-25g. Molecular Weight 461.38. See USA prepack pricing. |  |
| Eriochrome Blue Black R | Eriochrome Blue Black R. Group: Biochemicals. Alternative Names: Mordant Black 17; CI 1575. Grades: Highly Purified. CAS No. 2538-85-4. Pack Sizes: 1kg. US Biological Life Sciences. | Worldwide |
| Eriochrome Blue Black R ≥72% (Dye content) | Eriochrome Blue Black R ≥72% (Dye content). Group: Biochemicals. Grades: Reagent Grade. CAS No. 2538-85-4. Pack Sizes: 25g, 100g, 1Kg. US Biological Life Sciences. | Worldwide |
| Eriochrome cyanine R | 100g Pack Size. Group: Stains & Indicators. Formula: C23H15Na3O9S. CAS No. 3564-18-9. Prepack ID 53361433-100g. Molecular Weight 536.4. See USA prepack pricing. | |
| Eriochrome Cyanine R | Eriochrome Cyanine R. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Eriochrome® Cyanine R | Eriochrome® Cyanine R. Group: Biochemicals. Grades: Highly Purified. CAS No. 3564-18-9. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C23H15Na3O9S. US Biological Life Sciences. | Worldwide |
| Eriocitrin | Eriocitrin is a flavonoid isolated from lemons that is a powerful antioxidant. Eriocitrin inhibits the proliferation of liver cancer cells by arresting the cell cycle in the S phase by upregulating p53, cyclin A, cyclin D3 and CDK6. Eriocitrin triggers apoptosis by activating intrinsic signaling pathways involving mitochondria[1][1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Eriodictyol 7-rutinoside; Eriodictyol 7-O-rutinoside. CAS No. 13463-28-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0636. |  |
| Eriodermin | It is a dichlorodepsidone from the lichen erioderma physcioides. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-4-carboxaldehyde, 2,7-dichloro-3-hydroxy-8-methoxy-1,6-dimethyl-11-oxo-; 2,8-dichloro-9-hydroxy-3-methoxy-1,7-dimethyl-6-oxobenzo[b][1,4]benzodioxepine-10-carbaldehyde; 4-formyl-2,7-dichloro-3-hydroxy-8-methoxy-1,6-dimethyldi-benzo[b,e][1,4]dioxepin-11-one; Eriodermine. CAS No. 92070-80-9. Molecular formula: C17H12Cl2O6. Mole weight: 383.18. | |
| Eriodictyol | Eriodictyol is a flavanone characteristic of lime, found mainly in juice. The glycosylated forms are eriocitrin (bound to a rutinoside) and neoeriocitrin (bound to a neohesperidose). Eriodictyol prevents some secondary effects of diabetes, such as diabetic retinopathy and biochemical changes in plasma (study in rats) (Bucolo et al., 2012). In addition, it has been reported that in in vitro studies, eriodictyol decreases insulin resistance and glucose absorption.Eriodictyol is used in biological studies as natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation. Eriodictyl is extracted from Yerba santa, an herb. The leaf is used to make medicine.Yerba santa is used for respiratory conditions including coughs, colds, tuberculosis, asthma, and chronic bronchitis. It is also used for fever and dry mouth. Some people use it to relieve muscle spasms, to loosen phlegm, and as a tonic. Group: Biochemicals. Alternative Names: (2S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one; (2S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one; 3',4',5,7-tetrahydroxy-flavanone; (+)-Eriodictyol; (2S)-Eriodictyol; (S)-3',4',5,7-Tetrahydroxyflavanone; 3',4',5,7-Tetrahydroxyflavanone; Huazhongilexone. Grades: Highly Purified. CAS No. 552-58-9. Pack Sizes: 10mg, 20mg, 50mg, 100mg. Molecular Formula: C15H12O6, Molecular Weight: 288.25. US Biological | Worldwide |
| Eriodictyol | Eriodictyol. CAS No. 552-58-9/4049-38-1. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  |
| Eriodictyol | Eriodictyol is a natural flavonoid found in the fruits of Citrus sinensis (L.) Osbeck. Eriodictyol exhibits activities of antidiabetic, anti-inflammatory and antioxidant. Eriodictyol can increases glucose uptake and improves insulin resistance. Synonyms: (S)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4-benzopyrone; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one; 3',4',5,7-tetrahydroxyflavanone; 4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-. Grade: >97%. CAS No. 552-58-9. Molecular formula: C15H12O6. Mole weight: 288.25. | |
| Eriodictyol | Eriodictyol ((±)-Huazhongilexone; Dihydroluteolin) is an orally active TRPV1 receptor antagonist (IC50=44-47 nM, rTRPV1) with antioxidant and anti-inflammatory activities. Eriodictyol effectively inhibits lipid peroxidation and the release of proinflammatory cytokines by specifically antagonizing the TRPV1 receptor and activating the Nrf2 signaling pathway. Eriodictyol reduces the levels of ICAM-1, VEGF, eNOS and TNF-α in the retina and maintains the integrity of the blood-retinal barrier. Eriodictyol alleviates oxidative stress-induced apoptosis and hyperalgesia, enhances the activity and cytotoxicity of immune cells (such as B lymphocytes, NK cells and macrophages), and increases the levels of antioxidant enzymes simultaneously. Eriodictyol can be used in the research of diabetic retinopathy, acute lung injury and various pain-related diseases[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Huazhongilexone. CAS No. 552-58-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0637. | |
| Eriodictyol 7,3'-dimethyl ether | Eriodictyol 7,3'-dimethyl ether is a natural compound isolated from the herbs of Blumea balsamifera. Synonyms: (2S)-5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-2,3-dihydrochromen-4-one. Grade: 98.0%. CAS No. 54352-60-2. Molecular formula: C17H16O6. Mole weight: 316.30. | |
| Eriodictyol 7-O-glucoside | Eriodictyol 7-O-glucoside is isolated from the herbs of Dracocephalum rupestre. It has protective effect on cisplatin-induced toxicity. Synonyms: (S)-2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-4H-1-benzopyran-4-one; eriodictyol-7-glucoside. Grade: 95%. CAS No. 38965-51-4. Molecular formula: C21H22O11. Mole weight: 450.39. | |
| Eriodictyol-7-O-glucoside | Eriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is an Nrf2 activator. Eriodictyol-7-O-glucoside exhibits significant scavenging effects on both hydroxyl radicals and superoxide anions, with IC50 values of 0.28 mM and 0.30 mM, respectively. Eriodictyol-7-O-glucoside increases the nuclear localization of Nrf2 and induces the expression of the Nrf2/ARE-dependent genes. Eriodictyol-7-O-glucoside provides protection against oxygen and glucose deprivation (OGD)-induced oxidative insult. Eriodictyol-7-O-glucoside demonstrates neuroprotective efficacy in a rat model of focal cerebral ischemia (MCAO). Eriodictyol-7-O-glucoside can be used for the study of stroke[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Eriodictyol 7-O-β-D-glucoside. CAS No. 38965-51-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N3847. | |
| Eriodictyol chalcone | Eriodictyol chalcone possesses both anti-aromatase and anti-17β-HSD activity. Synonyms: 2',3,4,4',6'-Pentahydroxychalcone; 3,4,2',4',6'-Pentahydroxychalcone. CAS No. 14917-41-0. Molecular formula: C15H12O6. Mole weight: 288.25. | |
| Eriosema Psoraleoides Powder | Eriosema Psoraleoides Powder. |  CA, FL & NJ |
| Eriostemoic acid | Eriostemoic acid. Synonyms: 2H,8H-Benzo[1,2-b:3,4-b']dipyran-6-propionic acid, 5-methoxy-2,2,8,8-tetramethyl- (7CI,8CI); 5-Methoxy-2,2,8,8-tetramethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-6-propanoic acid. CAS No. 26535-36-4. Molecular formula: C20H24O5. Mole weight: 344.4. | |
| Erismodegib | Erismodegib. Group: Biochemicals. Alternative Names: rel-N-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)-1,1'-biphenyl]-3-carboxamide; LDE 225; NVP-LDE 225. Grades: Highly Purified. CAS No. 956697-53-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C26H26F3N3O3. US Biological Life Sciences. | Worldwide |
| Eritadenine | Hypocholesterolemic isolated from shiitake mushrooms, effecting phospholipid and linoleic acid metabolisms. Specifically, Eritadenine is a potent inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH), decreasing total cholesterol levels in plasma. Group: Biochemicals. Alternative Names: (αR, βR)-6-Amino-α, β-dihydroxy-9H-purine-9-butanoic Acid; 4-(6-Amino-9H-purin-9-yl)-4-deoxy-D-erythronic Acid; 4-(6-Aminopurin-9-yl)-4-deoxy-D-erythronic Acid; Lentinacin; Lentysine; 4-(9-Adenyl)-D-erythro-2,3-dihydroxybutyric Acid; D-Eritadenine. Grades: Highly Purified. CAS No. 23918-98-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Eritadenine Acetonide | Eritadenine Acetonide is an intermediate in the synthesis of Eritadenine, which is an inhibitor of S-adenosine-L-homocysteine hydrolase (SAHH) with hypocholesterolemic activity. Synonyms: (4R-cis)-5-[(6-Amino-9H-purin-9-yl)methyl]-2,2-dimethyl-1,3-dioxolane-4-carboxylic Acid; D-4-(6-Amino-9H-purin-9-yl)-4-deoxy-2,3-O-isopropylidene-erythronic Acid; 4-(6-Amino-9H-purin-9-yl)-4-deoxy-2,3-O-isopropylidene-D-erythronic Acid; 4-(6-Aminopurin-9-yl)-4-deoxy-2,3-O-isopropylidene-D-erythronic Acid; 1,3-Dioxolane-4-carboxylic acid, 5-[(6-amino-9H-purin-9-yl)methyl]-2,2-dimethyl-, (4R-cis)-. CAS No. 29031-25-2. Molecular formula: C12H15N5O4. Mole weight: 293.28. | |
| Eritoran | Eritoran is a TLR4 antagonist that is developed for the treatment of severe sepsis. Synonyms: ERITORAN; 185955-34-4; Eritoran [INN]; E5564; CHEMBL501259; [(2R,3R,4R,5S,6R)-4-decoxy-5-hydroxy-6-[[(2R,3R,4R,5S,6R)-4-[(3R)-3-methoxydecoxy]-6-(methoxymethyl)-3-[[(Z)-octadec-11-enoyl]amino]-5-phosphonooxyoxan-2-yl]oxymethyl]-3-(3-oxotetradecanoylamino)oxan-2-yl] dihydrogen phosphate; CHEBI:68609; 551541VI0Y; 3-O-decyl-2-deoxy-6-O-(2-deoxy-3-O-(3-methoxydecyl)-6-O-methyl-2-((1-oxo-11-octadecenyl. Grade: 95%. CAS No. 185955-34-4. Molecular formula: C66H126N2O19P2. Mole weight: 1313.66. | |
| ERK1/2 inhibitor 1 | ERK1/2 inhibitor 1 is a potent and orally bioavailable ERK1/2 inhibitor, inhibiting ERK1 up to 60% at 1 nM and inhibiting ERK2 with an IC50 of 3.0 nM. Synonyms: 2H-Isoindole-2-acetamide, 6-[5-chloro-2-[(tetrahydro-2H-pyran-4-yl)amino]-4-pyrimidinyl]-1,3-dihydro-N-[(1S)-2-hydroxy-1-(3-methylphenyl)ethyl]-α-methyl-1-oxo-, (αR)-; (2R)-2-{6-[5-Chloro-2-(tetrahydro-2H-pyran-4-ylamino)-4-pyrimidinyl]-1-oxo-1,3-dihydro-2H-isoindol-2-yl}-N-[(1S)-2-hydroxy-1-(3-methylphenyl)ethyl]propanamide. Grade: ≥95%. CAS No. 2095719-90-5. Molecular formula: C29H32ClN5O4. Mole weight: 550.05. | |
| ERK1/2 inhibitor 1 | ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2095719-90-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112287. | |
| ERK1/2 inhibitor 3 | ERK1/2 inhibitor 3, a potent ERK1/2 inhibitor, has the potential to study or prevent cancer, inflammation, or other proliferative diseases. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of MAPK family. (Extracted from patent WO2021218912A1, compound 1). Synonyms: (S)-2-(6-(5-chloro-2-((tetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)-1,1-dioxidobenzo[d]isothiazol-2(3H)-yl)-N-((S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl)propanamide. CAS No. 2737294-99-2. Molecular formula: C28H31ClFN5O6S. Mole weight: 620.09. | |
| ERK1/2 inhibitor 4 | ERK1/2 inhibitor 5, a potent ERK1/2 inhibitor, has the potential to study or prevent cancer, inflammation, or other proliferative diseases. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of MAPK family. (Extracted from patent WO2020238776A1). Synonyms: Thieno[3,2-c]pyridine-5(4H)-acetamide, 2-[5-chloro-2-[(tetrahydro-2H-pyran-4-yl)amino]-4-pyrimidinyl]-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]-6,7-dihydro-α-methyl-4-oxo-, (αR)-. CAS No. 2490396-99-9. Molecular formula: C28H31ClFN5O5S. Mole weight: 604.09. | |
| ERK1/2 inhibitor 6 | ERK1/2 inhibitor 6, a potent ERK1/2 inhibitor, has the potential to study or prevent cancer, inflammation, or other proliferative diseases. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of MAPK family. (Extracted from patent WO2021063335A1, compound 1). Synonyms: (R)-2-(6-(5-chloro-2-((tetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)-4-oxopyrrolo[2,1-f][1,2,4]triazin-3(4H)-yl)-N-((S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl)propanamide. CAS No. 2634816-13-8. Molecular formula: C27H29ClFN7O5. Mole weight: 586.01. | |
| ERK2 IN-1 | ERK2 IN-1 is a selective inhibitor of ERK2 with an IC50 of 7 nM. Synonyms: (3S)-N-[3-(4-Fluorophenyl)-1H-indazol-5-yl]-3-(methylsulfanyl)-1-(2-oxo-2-{4-[4-(2-pyrimidinyl)phenyl]-3,6-dihydro-1(2H)-pyridinyl}ethyl)-3-pyrrolidinecarboxamide; 3-Pyrrolidinecarboxamide, 1-[2-[3,6-dihydro-4-[4-(2-pyrimidinyl)phenyl]-1(2H)-pyridinyl]-2-oxoethyl]-N-[3-(4-fluorophenyl)-1H-indazol-5-yl]-3-(methylthio)-, (3S)-. Grade: ≥95%. CAS No. 1093061-47-2. Molecular formula: C36H34FN7O2S. Mole weight: 647.76. | |
| ERK5-IN-1 | ERK5-IN-1 is a potent ERK5 inhibitor with an IC50 of 87±7 nM. ERK5-IN-1 also inhibits LRRK2[G2019S] with an IC50 of 26 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1234479-76-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14403. | |
| ERK5-IN-2 | ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively. ERK5-IN-2 does not interact with the BRD4 bromodomain. ERK5-IN-2 suppresses both tumor xenograft growth and basic fibroblast growth factor (bFGF) driven Matrigel plug angiogenesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1888305-96-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128341. | |
| ERK5-IN-2 | ERK5-IN-2 is a submicromolar selective ERK5 inhibitor with oral activity, which can inhibit tumor xenograft growth and basic fibroblast growth factor (bFGF)-driven Matrigel plug angiogenesis. Synonyms: 4-(2-Bromanyl-6-Fluoranyl-Phenyl)Carbonyl-{N}-Pyridin-3-Yl-1{H}-Pyrrole-2-Carboxamide; SCHEMBL17607180; BCP32587; EX-A4938. Grade: 98%. CAS No. 1888305-96-1. Molecular formula: C17H11BrFN3O2. Mole weight: 388.2. | |
| ERK-IN-2 | ERK-IN-2, an ERK2 inhibitor probe (IC50 = 1.8 nM), may cause off-target toxicity and/or off-target activity at doses >10 μM. Synonyms: 1-[4-(Hydroxymethyl)-1H-pyrazolo[4,3-c]pyridin-6-yl]-3-[(1R)-1-phenylethyl]urea hydrochloride (1:1); Urea, N-[4-(hydroxymethyl)-1H-pyrazolo[4,3-c]pyridin-6-yl]-N'-[(1R)-1-phenylethyl]-, hydrochloride (1:1). Grade: ≥95%. Molecular formula: C16H18ClN5O2. Mole weight: 347.80. | |
| ERK-IN-3 | ERK-IN-3 is a potent and orally active ERK inhibitor that can be used in cancer research caused by RAS mutations. It inhibits ERK1/2 with low single-digit nM IC50 values. Synonyms: N-[(1S)-2-amino-1-(3-chloro-5-fluorophenyl)ethyl]-1-{5-methyl-2-[(oxan-4-yl)amino]pyrimidin-4-yl}-1H-imidazole-4-carboxamide; ASN007 free base; NSC-828319; N-[(1S)-2-Amino-1-(3-chloro-5-fluorophenyl)ethyl]-1-[5-methyl-2-(tetrahydro-2H-pyran-4-ylamino)-4-pyrimidinyl]-1H-imidazole-4-carboxamide. Grade: ≥99%. CAS No. 2055597-12-9. Molecular formula: C22H25ClFN7O2. Mole weight: 473.93. | |
| ERK-IN-3 benzenesulfonate | ERK-IN-3 benzenesulfonate is a potent and orally active ERK inhibitor that can be used in cancer research caused by RAS mutations. It inhibits ERK1/2 with low single-digit nM IC50 values. Synonyms: 1H-Imidazole-4-carboxamide, N-[(1S)-2-amino-1-(3-chloro-5-fluorophenyl)ethyl]-1-[5-methyl-2-[(tetrahydro-2H-pyran-4-yl)amino]-4-pyrimidinyl]-, compd. with benzenesulfonate (1:1). Grade: ≥98%. CAS No. 2055597-39-0. Molecular formula: C28H31ClFN7O5S. Mole weight: 632.11. | |
| ERK Inhibitor | ERK inhibitor, a reversible thiazolidinedione compound, is a cell-permeable inhibitor that binds ERK2 near its docking domain with a KD of 5 μM and prevents its interaction with protein substrates. Synonyms: Extracellular Regulated Kinase Inhibitor; 3-(2-aminoethyl)-5-[(4-ethoxyphenyl)methylene]-2,4-thiazolidinedione, monohydrochloride. Grade: ≥95%. CAS No. 1049738-54-6. Molecular formula: C14H16N2O3S·HCl. Mole weight: 328.8. | |
| ER-Laurdan | ER-Laurdan is a derivative of the membrane-permeable fluorescent probe Laurdan (HY-D0080) that targets the endoplasmic reticulum (ER). As a membrane fluidity reporter, ER-Laurdan specifically localizes to the ER luminal membrane, and exhibits a prominent solvatochromic response to fluidity changes caused by membrane packing and exogenous saturated fatty acid stress. ER-Laurdan shows no overlapping localization with mitochondria, enables quantitative analysis of ER membrane fluidity via generalized polarization ratio measurement, and allows automatic signal masking with the help of ER markers. With high specificity and quantitative capability, ER-Laurdan serves as an important tool for investigating metabolic disorders and associated changes in the physical properties of cell membranes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3091879-77-2. Pack Sizes: 1 mg. Product ID: HY-N16308. | |
| Erlizumab | Erlizumab is a humanized monoclonal antibody that targets CD18. Erlizumab has been investigated as a therapy for hemorrhagic shock. Synonyms: rhuMAb. Grade: 95%. CAS No. 211323-03-4. | |
| Erlizumab | Erlizumab (rhuMAb) is a monoclonal antibody against the Integrin b2/ITGB2/CD18 subunit of the Mac-1 receptor. Erlizumab can reduce reperfusion injury in myocardial infarction[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: rhuMAb. CAS No. 211323-03-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99946. | |
| Erlose | Erlose is a widely utilized pharmaceutical in the biomedical sector, serving as a prominent role for studying Type 2 diabetes. Its mechanism of action entails augmenting glycemic regulation while concurrently amplifying the responsiveness of cells towards insulin. Synonyms: a-D-Glc-(1→4)-a-D-Glc-(1→2)-b-D-Fru; a-Maltosyl b-fructofuranoside; β-D-Fructofuranosyl O-α-D-glucopyranosyl-(1→4)-α-D-glucopyranoside; Fructomaltose. CAS No. 13101-54-7. Molecular formula: C18H32O16. Mole weight: 504.44. | |
| Erlose | Erlose. CAS No. 13101-54-7. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. | |
| Erlosiban | Erlosiban, an iminopyrrolidin derivative, has been found to be a nonpeptide oxytocin receptor antagonist that could probably be used in the treatment of female infertility and preterm labour. It is still under Phase II clinical trail in Preterm labour. Synonyms: UOBE-001; OBE001; OBE001; NII-3765U8A1EC; CHEMBL1254025; 3765U8A1EC; Erlosiban; Erlosiban [INN]; [(2S,4Z)-2-(hydroxymethyl)-4-methoxyiminopyrrolidin-1-yl]-[4-(2-methylphenyl)phenyl]methanone. Grade: 98%. CAS No. 1477482-19-1. Molecular formula: C20H22N2O3. Mole weight: 338.41. | |
| Erlotinib | Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer[1]. Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP-358774; NSC 718781; OSI-774. CAS No. 183321-74-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-50896. | |
| Erlotinib | Erlotinib. Uses: For analytical and research use. Alternative Names: N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine. CAS No. 183321-74-6. Molecular formula: C22H23N3O4. Mole weight: 393.44. Catalog: APB183321746. | |
| Erlotinib | Erlotinib is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Erlotinib has been indicated for non-small cell lung cancer (NSCLC) and pancreatic cancer therapy. Synonyms: CP358774; CP 358774; CP-358774; NSC 718781; NSC718781; NSC-718781. Grade: >98%. CAS No. 183321-74-6. Molecular formula: C22H23N3O4. Mole weight: 393.44. | |
| Erlotinib-[13C6] Hydrochloride | Erlotinib-[13C6] Hydrochloride is the labelled salt of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Erlotinib is a medication used to treat non-small cell lung cancer and pancreatic cancer. Synonyms: Erlotinib-13C6 Hydrochloride; N-[3-ethynyl(1,2,3,4,5,6-13C6)phenyl]-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride; Tarceva-13C6. Grade: 95% by HPLC; 98% atom 13C. CAS No. 1210610-07-3. Molecular formula: C16[13C]6H23N3O4.HCl. Mole weight: 435.82. | |
| Erlotinib-3-vinyl Hydrochloride | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 6,7-Bis(2-methoxyethoxy)-N-(3-vinylphenyl)quinazolin-4-amine hydrochloride; 4-Quinazolinamine, N-(3-ethenylphenyl)-6,7-bis(2-methoxyethoxy)-, hydrochloride (1:1). Grade: 95%. CAS No. 1624294-38-7. Molecular formula: C22H26ClN3O4. Mole weight: 431.91. | |
| Erlotinib Carboxylic Acid | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Erlotinib Metabolite M6; Erlotinib Acid. Grade: > 95%. Molecular formula: C22H25N3O6. Mole weight: 427.46. | |
| Erlotinib (CP-358774) | Erlotinib is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Erlotinib induces autophagy. Group: Inhibitors. Alternative Names: CP358774, NSC 718781,OSI-774. CAS No. 183321-74-6. Pack Sizes: 50mg. Product ID: S7786. Formula: C22H23N3O4. Smiles: COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Erlotinib-d6 | Erlotinib-d6 (CP-358774 D6) is a deuterium labeled Erlotinib (CP-358774). Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR[1]. Erlotinib-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP-358774-d6; NSC 718781-d6; OSI-774-d6. CAS No. 1034651-23-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-50896S. | |
| Erlotinib-[d6] | Erlotinib-[d6] is the labelled analogue of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Erlotinib is a medication used to treat non-small cell lung cancer and pancreatic cancer. Synonyms: Erlotinib D6. Grade: 95% by HPLC; 98% atom D. CAS No. 1034651-23-4. Molecular formula: C22H17D6N3O4. Mole weight: 399.48. | |
| Erlotinib-[d6] Hydrochloride | Erlotinib-[d6] Hydrochloride is the labelled analogue of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Erlotinib is a medication used to treat non-small cell lung cancer and pancreatic cancer. Synonyms: N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy-d3)-4-quinazolinamine Hydrochloride; 6,7-Bis(2-methoxyethoxy-d3)-4-(3-ethynylanilino)quinazoline Hydrochloride; [6,7-Bis(2-methoxyethoxy-d3)quinazolin-4-yl]-(3-ethynylphenyl)amine Hydrochloride; Erlotinib D6 Hydrochloride. Grade: 98% by CP; 98% atom D. CAS No. 1189953-78-3. Molecular formula: C22H18D6ClN3O4. Mole weight: 435.93. | |
| Erlotinib hydrochloride | Erlotinib HCl potently inhibits EGFR activation in intact cells including HNS human head and neck tumor cells (IC50 = 20 nM), DiFi humancolon cancer cells and MDA MB-468 human breast cancer cells. Uses: Antineoplastic agents. Synonyms: OSI-744; OSI744; OSI 744; Tarceva; 4-(m-Ethynylanilino)-6,7-bis(2-methoxyethoxy)quinazoline monohydrochloride; 6,7-bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride. Grade: >98%. CAS No. 183319-69-9. Molecular formula: C22H23N3O4.HCl. Mole weight: 429.90. | |
| Erlotinib hydrochloride | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H24ClN3O4. CAS No. 183319-69-9. Prepack ID 82977875-1g. Molecular Weight 429.9. See USA prepack pricing. | |
| Erlotinib Hydrochloride | Erlotinib hydrochloride is a small-molecule tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR). It is available as oral tablets and represents a targeted therapy for certain non-small cell lung cancers and pancreatic cancer. The drug reversibly binds to the intracellular kinase domain of EGFR, blocking downstream signaling pathways critical for tumor cell proliferation and survival. Applications: It is indicated for the first-line treatment of metastatic non-small cell lung cancer harboring egfr exon 19 deletions or exon 21 (l858r) substitution mutations, as detected by an fda-approved test. it is also indicated for maintenance therapy in patients with locally advanced or metastatic nsclc following stabilization after first-line platinum-based chemotherapy. additionally, it is approved in combination with gemcitabine for the first-line treatment of locally advanced, unresectable, or metastatic pancreatic cancer. rash and diarrhea are the most common dose-limiting toxicities. Category: Anti-tumor apis. Synonyms: erlotinib HCl; Tarceva; OSI-774; CP 358774; DA87705X9K; CP-358. CAS No. 183319-69-9. Product ID: API183319699. Molecular formula: C22H24ClN3O4. Mole weight: 429.9. EINECS: 620-491-0. InChIKey: GTTBEUCJPZQMDZ-UHFFFAOYSA-N. Appearance: White to off-white powder. |  |
| Erlotinib Hydrochloride | Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP-358774 hydrochloride; NSC 718781 hydrochloride; OSI-774 hydrochloride. CAS No. 183319-69-9. Pack Sizes: 50 mg; 100 mg; 500 mg; 1 g; 10 g. Product ID: HY-12008. | |
| Erlotinib, Hydrochloride, Free Base, EGFR Inhibitor (CP-358774, OSI-774, Ro 50-8231) | A free base form of the EGFR inhibitor Erlotinib Hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 183321-74-6. Pack Sizes: 100mg, 1g. US Biological Life Sciences. | Worldwide |
| Erlotinib Hydroxy Metabolite | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Hydroxy Erlotinib; N-(3-Ethynyl-4-hydroxy-phenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl] amine hydrochloride. Grade: > 95%. CAS No. 882420-22-6. Molecular formula: C22H23N3O5. Mole weight: 409.45. | |
| Erlotinib impurity 1 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N-(3-(1-chlorovinyl)phenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine. Grade: > 95%. Molecular formula: C22H24ClN3O4. Mole weight: 429.91. | |
| Erlotinib impurity 1 | Erlotinib impurity 1. Uses: For analytical and research use. CAS No. 1809951-10-7. Molecular formula: C28H34N4O9. Mole weight: 570.6. Catalog: APB1809951107. | |
| Erlotinib Impurity 1 | Erlotinib Impurity 1. Uses: For analytical and research use. Alternative Names: 4-chloro-6,7-bis(2-chloroethoxy)quinazoline. CAS No. 183322-21-6. Molecular formula: C12H11Cl3N2O2. Mole weight: 319.99. Catalog: APB183322216. | |
| Erlotinib Impurity 10 | Erlotinib Impurity 10. Uses: For analytical and research use. Alternative Names: N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine. CAS No. 183319-69-9. Molecular formula: C22H23N3O4. Mole weight: 393.17. Catalog: APB183319699. | |
| Erlotinib Impurity 11 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: N'-[2-Cyano-4,5-bis(2-methoxyethoxy)phenyl]-N,N-dimethylimidoformamide. Grade: > 95%. CAS No. 950596-59-5. Molecular formula: C16H23N3O4. Mole weight: 321.38. | |
| Erlotinib Impurity 12 | A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: (E)-2-(((dimethylamino)methylene)amino)-4,5-bis(2-methoxyethoxy)benzamide. Grade: > 95%. Molecular formula: C16H25N3O5. Mole weight: 339.39. | |
| Erlotinib Impurity 12 | Erlotinib Impurity 12. Uses: For analytical and research use. Alternative Names: 2-amino-4,5-bis(2-methoxyethoxy)benzamide. CAS No. 236750-62-2. Molecular formula: C13H20N2O5. Mole weight: 284.14. Catalog: APB236750622. | |
| Erlotinib Impurity 13 | Erlotinib Impurity 13. Uses: For analytical and research use. Alternative Names: 6,7-bis(2-methoxyethoxy)quinazolin-4(3H)-one. CAS No. 179688-29-0. Molecular formula: C14H18N2O5. Mole weight: 294.12. Catalog: APB179688290. | |
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