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| Product | Description | |
|---|---|---|
| FPPQ | FPPQ is a dual-acting 5-HT3 (Ki = 0.9 nM) and 5-HT6 (Ki = 3 nM) receptor antagonist that exhibits antipsychotic and procognitive properties. CAS No. 1648745-46-3. Molecular formula: C21H19FN4O2S. Mole weight: 410.46. |  |
| FPPS-IN-11 | FPPS-IN-11 is a novel allosteric non-bisphosphonate inhibitor of farnesyl pyrophosphate synthase (FPPS). Synonyms: 1-(Carboxymethyl)-1H-benzo[g]indole-2-carboxylic acid. Grade: >98%. CAS No. 1250273-31-4. Molecular formula: C15H11NO4. Mole weight: 269.25. | |
| FPR1 antagonist 1 | FPR1 antagonist 1 (compound 24a) is a formyl peptide receptor 1 (FPR1) antagonist with an IC50 of 25 nM. FPR1 antagonist 1 inhibits cell growth through a combined effect on cell proliferation and apoptosis and reduces cell migration, while inducing an increase in angiogenesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3053980-28-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156293. |  |
| FPR1 antagonist 3 | FPR1 antagonist 3 (compound 10) is a potent and selective FPR1 antagonist. FPR1 antagonist 3 inhibits superoxide anion generation and elastase release with IC50s of 0.33 and 0.84 μM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3058943-53-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176403. | |
| FPR2 agonist 3 | FPR2 agonist 3 (compound CMC23) can limit the lactate dehydrogenase release in LPS (HY-D1056) -stimulated cultures and decrease the levels of pro-inflammatory IL-1β and IL-6. FPR2 agonist 3 decrease the level of phosphor-STAT3 via the STAT3/SOCS3 signaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2829263-19-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155335. | |
| FPR A14 | FPR A14. Group: Biochemicals. Grades: Purified. CAS No. 329691-12-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| FPR A14 | FPR A14 is a formyl peptide receptor (FPR) agonist that potently activates neutrophils in vitro (EC50 = 42 and 630 nM for neutrophil chemotaxis and Ca2+ mobilization, respectively). Synonyms: AG 14; AG14; AG-14; 1,3-Benzodioxolane-5-carboxylic acid 4'-benzyloxy-3'-methoxybenzylidene hydrazide. Grade: ≥99% by HPLC. CAS No. 329691-12-5. Molecular formula: C23H20N2O5. Mole weight: 404.42. | |
| FPR Agonist 43 | FPR Agonist 43 (compound 43) is a dual formyl peptide receptor 1 (FPR1) and formyl peptide receptor 2 (FPR2)/ALX agonist[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 903895-98-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19574. | |
| FPS-ZM1 | FPS-ZM1 is a high-affinity and BBB-permeable RAGE inhibitor with a Ki of 25 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 945714-67-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-19370. | |
| FPS-ZM1 | FPS-ZM1 is a high-affinity RAGE-specific blocker that inhibits amyloid-β binding to the V domain of RAGE with Ki of 25 ± 5 nM in RAGE-transfected CHO cells. It binds exclusively to RAGE and inhibits β-secretase activity and Aβ production. It also suppresses microglia activation and the neuroinflammatory response in brain. It penetrates the blood-brain barrier and binds to RAGE, thus reducing the protein levels of various cytokines. It inhibits RAGE-mediated influx of circulating Aβ40 and Aβ42 into the brain. It is not toxic to mice and can easily cross the blood-brain barrier in vivo. It might be a novel therapeutic agent to treat AD patients. Uses: Fps-zm1 might be a novel therapeutic agent to treat ad patients. Synonyms: FPS-ZM1; FPS ZM1; FPSZM1; FPS-ZM 1; FPS ZM-1; FPSZM 1; N-benzyl-4-chloro-N-cyclohexylbenzaMide; 4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide. Grade: >98 %. CAS No. 945714-67-0. Molecular formula: C20H22ClNO. Mole weight: 327.85. | |
| FPTQ | FPTQ is a potent mGluR1 antagonist and has anti-oxidant and anti-inflammatory effects in vitro and in vivo. Synonyms: 6-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl)quinoline. Grade: 99%. CAS No. 864863-72-9. Molecular formula: C17H12FN5. Mole weight: 305.31. | |
| FP-TZTP | FP-TZTP. Group: Biochemicals. Alternative Names: 3-[4-[(3-Fluoropropyl)thio]-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine. Grades: Highly Purified. CAS No. 424829-90-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C11H16FN3S2. US Biological Life Sciences. | Worldwide |
| FQI 1 | FQI 1 is a cell-permeable and reversible inhibitor of α-globin transcription factor CP2 (LSF; IC50 = 2.1 μM) and an antiproliferative. FQI 1 induces apoptosis in LSF-overexpressing cells, including Hepatocellular carcinoma (HCC cells). FQI 1 acts via inhibiting LSF-DNA binding. Uses: Antiproliferative. Synonyms: FQI 1; FQI1; FQI-1; 8-(2-ethoxyphenyl)-7,8-dihydro[1,3]dioxolo[4,5-g]quinolin-6(5H)-one; 8-(2-Ethoxy-phenyl)-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one. Grade: 99%. CAS No. 599151-35-6. Molecular formula: C18H17NO4. Mole weight: 311.33. | |
| FR054 | FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 35954-65-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-124909A. | |
| FR 110302 | This active molecular is a potent 5-lipoxygenase inhibitor which was originated by Fujisawa company for treating asthma. No-Development was reported for asthma in Japan. Synonyms: FR 110302; FR110302; FR-110302. 2,2-dibutyl-1,2,3,4-tetrahydro-5-(2-quinolinylmethoxy)-1-Naphthalenol. Grade: 98%. CAS No. 119256-94-9. Molecular formula: C28H35NO2. Mole weight: 417.58. | |
| FR 113680 | FR 113680 is a novel tripeptide substance P antagonist with NK1 receptor selectivity originated by Fujisawa for the treatment of Asthma. But no development are reported yet. Uses: Asthma. Synonyms: FR 113680; FR113680; FR-113680; Ac-Thr-trp(cho)-phe-N-mebzl. Ac-Thr-trp(cho)-phe-N-mebzl; N-acetyl-L-threonyl-1-formyl-D-tryptophyl-N-methyl-N-(phenylmethyl)-L-Phenylalaninamide. Grade: 98%. CAS No. 126088-92-4. Molecular formula: C35H39N5O6. Mole weight: 625.72. | |
| FR 121196 | FR 121196 is a potential antidementia drug originated by Fujisawa. Mechanism of Action is not undefined. FR 121196 can ameliorate the impaired memory of rat in the Morris water maze. No development was reported for Cognition disorders in Japan. Uses: Cognition disorders. Synonyms: FR 121196; FR 121196; FR 121196. N-(4-acetylpiperazin-1-yl)-4-fluorobenzenesulfonamide. Grade: 98%. CAS No. 133920-65-7. Molecular formula: C12H16FN3O3S. Mole weight: 301.34. | |
| Fr 122047 hydrochloride | Fr 122047 hydrochloride. CAS No. 130717-51-0. Purity: >98 %. Product ID: ACM130717510. Molecular formula: C23H25N3O3S.HCl. Mole weight: 459.99. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| FR 122047 hydrochloride | FR 122047 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 130717-51-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR 122047 hydrochloride | FR-122047 is a selective cyclooxygenase-1 (COX-1) inhibitor with IC50 values is 0.028μM for COX-1 and 65 μM for COX-2. FR-122047 displays 2300 fold greater selectivity towards inhibition of COX-1 over COX-2. It shows analgesic, anti-platelet and anti-inflammatory properties. No development was reported for the treatment of Pain, Rheumatoid arthritis and Thrombosis. Uses: Pain; rheumatoid arthritis; thrombosis. Synonyms: FR 122047 hydrochloride; 1-[[4,5-bis-(4-Methoxyphenyl)-2-thiazolyl]carbonyl]-4-methylpiperazine hydrochloride. Grade: >98 %. CAS No. 130717-51-0. Molecular formula: C23H25N3O3S.HCl. Mole weight: 459.99. | |
| FR122047 hydrochloride hydrate | FR122047 is a selective inhibitor of COX-1 with an IC50 value of 0.028 μM. Synonyms: 1-[[4,5-bis(4-methoxyphenyl)-2-thiazolyl]carbonyl]-4-methyl-piperazine, monohydrochloride, monohydrate. Grade: ≥98%. Molecular formula: C23H25N3O3S·HCl·H2O. Mole weight: 478. | |
| FR 139317 | FR 139317 is a selective Endothelin A receptor antagonist originated by Fujisawa. (Ki values are 1 nM and 7.3 μM at ETA and ETB subtypes respectively). No development was reported for the treatment of Cerebrovascular disorders, Coronary disorders, Diabetic nephropathies, Heart failure, Hypertension, Ischaemic heart disorders, Myocardial infarction and Renal failure. Uses: Cerebrovascular disorders; coronary disorders; diabetic nephropathies; heart failure; hypertension; ischaemic heart disorders; myocardial infarction; renal failure. Synonyms: FR 139317; FR139317; FR139317; PD 147953; PD147953; PD-147953; 2-((1-(Hexahydro-1H-azepinyl)carbonyl)amino-4-methylpentanoyl)-3-(-(1-methyl-1H-indolyl)propionyl)amino-3-(2-pyridyl)propionic acid. Grade: 98 %. CAS No. 142375-60-8. Molecular formula: C33H44N6O5. Mole weight: 604.75. | |
| FR 139317 | FR 139317. Group: Biochemicals. Grades: Purified. CAS No. 142375-60-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR-167356 | FR-167356, a benzofuran derivative, has been found to be an acuolar ATPase inhibitor and could probablye be useful in studies of some lytic bone diseases. Synonyms: FR-167356; FR167356; FR 167356; UNII-XF02B1HC8R. DSSTox_CID_28148; DSSTox_RID_82712; 2,6-dichloro-N-[3-(2-hydroxypropan-2-yl)-2-methyl-1-benzofuran-7-yl]benzamide. Grade: 98%. CAS No. 174185-16-1. Molecular formula: C19H17Cl2NO3. Mole weight: 378.25. | |
| FR-167653 | FR-167653 is a p38 mitogen-activated protein kinase inhibitor, which suppresses the development of endometriosis in a murine model. FR-167653 meliorates murine bleomycin-induced pulmonary fibrosis. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: FR-167653; FR 167653; FR167653. CAS No. 158876-66-5. Molecular formula: C24H20FN5O6S. Mole weight: 525.51. | |
| FR-167653 Free base | FR-167653, a pyrazolo?triazin derivative, has been found to be a cytokine inhibitor as well as P38 mitogen-activated protein kinase inhibitor and was once studied as an anticoagulant. Synonyms: FR167653; FR-167653; FR 167653; 1,?2-Ethanedione, 1-[7-(4-fluorophenyl)?-3,?4-dihydro-8-(4-pyridinyl)?pyrazolo[5,?1-c]?[1,?2,?4]?triazin-2(1H)?-yl]?-2-phenyl-. Grade: 98%. CAS No. 158876-65-4. Molecular formula: C24H18FN5O2. Mole weight: 427.43. | |
| FR-168888 | FR-168888, a guanidine compound, has been found to be a sodium hydrogen antiporter inhibitor that was once studied in myocardial ischaemia therapy. Synonyms: FR-168888; FR 168888; FR168888; Benzamide, N-(aminoiminomethyl)-3-(hydroxymethyl)-5-(1H-pyrrol-1-yl)-, methanesulfonate (1:1). Grade: 98%. CAS No. 168620-46-0. Molecular formula: C14H18N4O5S. Mole weight: 354.38. | |
| FR-168888 Free Base | The free base of FR-168888, a guanidine compound, has been found to be a sodium hydrogen antiporter inhibitor that was once studied in myocardial ischaemia therapy. Synonyms: FR-168888 free base; FR 168888 free base; FR168888 free base; SCHEMBL1388039; SCHEMBL8300855; Benzamide, N-(aminoiminomethyl)-3-(hydroxymethyl)-5-(1H-pyrrol-1-yl)-. Grade: 98%. CAS No. 168620-45-9. Molecular formula: C13H14N4O2. Mole weight: 258.28. | |
| FR 171113 | FR 171113 is a protease-activated receptor 1 (PAR1) antagonist displaying significant antiplatelet activity in vitro. It inhibits thrombin TRAP-6-induced platelet aggregation (IC50 = 2.5 μM) with no effect on coagulation time. Synonyms: FR 171113; FR171113; FR-171113; 2-[3-(4-Chlorophenyl)-2-[(2,4-dichlorobenzoyl)imino]-4-oxo-5-thiazolidinylidene]-acetic acid methyl ester. Grade: ≥98% by HPLC. CAS No. 173904-50-2. Molecular formula: C19H11Cl3N2O4S. Mole weight: 469.73. | |
| FR 171113 | FR 171113. Group: Biochemicals. Grades: Purified. CAS No. 173904-50-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR 179642 | FR 179642 is an impurity of Micafungin, which is an antifungal agent. Synonyms: FR-179642; FR179642; Pneumocandin M1; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; CMICA; FR 133303. Grade: ≥95%. CAS No. 168110-44-9. Molecular formula: C35H52N8O20S. Mole weight: 936.89. | |
| FR-179642 | FR-179642. Group: Biochemicals. Grades: Highly Purified. CAS No. 168110-44-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C35H52N8O20S. US Biological Life Sciences. | Worldwide |
| FR 180204 | FR 180204. Group: Biochemicals. Grades: Purified. CAS No. 865362-74-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR 180204 | FR180204 is a novel and selective inhibitor of extracellular signal-regulated kinase (ERK), which may be a potential new therapy for rheumatoid arthritis.FR180204 showed activity to inhibit ERKs (IC50 values are 0.14 and 0.31 μM for ERK2 and ERK1 respectively). Synonyms: 865362-74-9; FR 180204; FR-180204; ERK inhibitor II; 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE; 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-2H-pyrazolo[3,4-c]pyridazin-3-amine; 4C7X7GV82C; CHEMBL259551; 1H-Pyrazolo(3,4-C)pyridazin-3-amine, 5-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-; 5-(2-Phenylpyrazolo(1,5-a)pyridin-3-yl)-2H-pyrazolo(3,4-C)pyridazin-3-amine; 5-{2-phenyl. Grade: 0.98. CAS No. 865362-74-9. Molecular formula: C9H11N5O4. Mole weight: 253.22. | |
| FR 180204 | FR 180204 is an ATP-competitive and selective ERK inhibitor. FR 180204 inhibits ERK1 and ERK2 with IC50s of 0.51 μM (Ki=0.31 μM) and 0.33 μM (Ki=0.14 μM), respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 865362-74-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12275. | |
| FR-181074 | FR-181074 may be a bio-active chemical to treat Male Sexual Dysfunction. Synonyms: 1-[(2-chlorophenyl)methyl]-3-(2-methylpropanoyl)-2-propylindole-6-carboxamide; FR-181074; FR181074; FR 181074; UNII-D3C5RV093V. Grade: >98%. CAS No. 184147-65-7. Molecular formula: C23H25ClN2O2. Mole weight: 396.91. | |
| FR-181157 | FR-181157, an oxazol derivative, has been found to be a prostaglandin mimetic and could have potential biological activities as a IP receptor agonist. Synonyms: FR-181157; FR 181157; FR181157; FR-181157 Free Base. (S)-FR-181157; SCHEMBL8057380; sodium; 2-[3-[[(1S)-2-(4,5-diphenyl-1,3-oxazol-2-yl)cyclohex-2-en-1-yl]methyl]phenoxy]acetate. Grade: 98%. CAS No. 171046-15-4. Molecular formula: C30H26NNaO4. Mole weight: 487.52. | |
| FR-181157 Free base | FR-181157 is an orally active prostacyclin mimetic that shows high potency and agonist efficacy at the IP receptor. Synonyms: sodium; 2-[3-[[(1S)-2-(4,5-diphenyl-1,3-oxazol-2-yl)cyclohex-2-en-1-yl]methyl]phenoxy]acetate; FR 181157; FR181157; 200433-03-0 (FR-181157 Free Base). Grade: >98%. CAS No. 200433-03-0. Molecular formula: C30H26NNaO4. Mole weight: 487.52. | |
| FR-181877 | FR-181877, an oxopyridazin derivative, has been found to be a nonprostanoid PGI2 agonist and could restrain the aggregation of human platelets induced by ADP. IC50: 0.081μM. Synonyms: FR-181877; FR 181877; FR181877. (-)-FR-181877; 2-[[(6S)-6-[(3-benzhydryl-6-oxopyridazin-1-yl)methyl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acid. Grade: 98%. CAS No. 172936-99-1. Molecular formula: C30H28N2O4. Mole weight: 480.56. | |
| FR-182024 | FR-182024, an azabicyclo derivative, has been found to have potential activity as an anti-Helicobacter pylori agent and was once stuied against helicobacter infections. Synonyms: FR-182024; FR 182024; FR182024. 9031SV3FWE; (6R,7R)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Grade: 98%. CAS No. 179034-83-4. Molecular formula: C18H16N4O4S3. Mole weight: 448.53. | |
| FR-182877 | FR-182877 is produced by the strain of Streptomyces sp. No. 9885. It has a strong effect on rat ascites and solid tumors in vivo, and has no antibacterial activity. Molecular formula: C24H32O5. Mole weight: 400.51. | |
| FR-182980 | FR-182980, a pyridine derivative, has been found to be a sterol O-acyltransferase inhibitor and was once studied in hypercholesterolaemia. Synonyms: FR-182980; FR182980; FR 182980; 1-cycloheptyl-1-[[4-(4-fluorophenoxy)phenyl]methyl]-3-[6-methyl-2,4-bis(methylsulfanyl)pyridin-3-yl]urea. Grade: 98%. CAS No. 179054-51-4. Molecular formula: C29H34FN3O2S2. Mole weight: 539.73. | |
| FR183998 | FR183998 is a Na+/H+ exchanger inhibitor. Inhibition of the Na+/H+ exchanger improves heart and brain injuries induced by I/R. Synonyms: FR-183998. Grade: 98%. CAS No. 239440-20-1. Molecular formula: C17H19Cl2N5O2S. Mole weight: 428.34. | |
| FR-186054 | FR-186054, a pyridine derivative, has been found to be a sterol O-acyltransferase inhibitor and was once studied in hyperlipidaemia. Synonyms: FR-186054; FR 186054; FR186054; 1-benzyl-3-[6-methyl-2,4-bis(methylsulfanyl)pyridin-3-yl]-1-[[3-(1H-pyrazol-5-yl)phenyl]methyl]urea. Grade: 98%. CAS No. 179053-90-8. Molecular formula: C26H27N5OS2. Mole weight: 489.66. | |
| FR-188582 | FR-188582, with anti-inflammatory and ulcerogenic properties, is a highly selective inhibitor of COX-2 with IC50=0.017 microM. Synonyms: 3-chloro-5-(4-methylsulfonylphenyl)-1-phenylpyrazole; FR 188582; FR188582; FR-188582. Grade: >98%. CAS No. 189699-82-9. Molecular formula: C16H13ClN2O2S. Mole weight: 332.8. | |
| FR-190809 | FR-190809 is a potent and orally efficacious ACAT inhibitor potentially for the treatment of Lipoprotein Disorders. Synonyms: 1-cycloheptyl-1-[[4-(4-fluorophenoxy)phenyl]methyl]-3-[6-methyl-2,4-bis(methylsulfonyl)pyridin-3-yl]urea; FR-190809; FR 190809; FR190809.N-cycloheptyl-N-(4-(4-fluorophenoxy)-benzyl)-N'-(2,4-bis(methylsulfonyl)-6-methylpyridin-3-yl)urea. Grade: >98%. CAS No. 215589-63-2. Molecular formula: C29H34FN3O6S2. Mole weight: 603.73. | |
| FR-191512 | It is a polyphenolic compound with anti-influenza A virus effect. Synonyms: FR191512. Molecular formula: C38H38O16. Mole weight: 750.70. | |
| FR-193262 | FR-193262 is a designed prostacyclin mimetic without PG skeleton which exhibits potent PGI2 agonistic activity with good selectivity for IP receptor and bioavailability. Synonyms: FR-193262; FR 193262; FR193262; sodium; 2-[[(5R)-5-[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetate; FR-193262; 187992-22-9(FR-193262); 314289-63-9 (FR-193262 Free Base). Grade: >98%. CAS No. 187992-22-9. Molecular formula: C31H29N2NaO4. Mole weight: 516.56. | |
| FR-193262 Free base | A bio-active organic chemical. Uses: A bio-active organic chemical. Synonyms: FR-193262; FR 193262; FR193262; 2-[[(5R)-5-[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acid. Grade: ≥98%. CAS No. 314289-63-9. Molecular formula: C31H30N2O4. Mole weight: 494.59. | |
| FR-193879 | FR-193879, a cephem derivative, is an efficacious anti-Helicobacter pylori cephalosporin. Synonyms: (6R,7R)-3-[[4-(2-amino-2-oxoethyl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; FR-193879; FR193879; FR 193879. Grade: >98%. CAS No. 194928-82-0. Molecular formula: C20H18N4O5S3. Mole weight: 490.58. | |
| FR194738 | FR194738 is a squalene epoxidase inhibitor. FR194738 inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 204067-52-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100303A. | |
| FR194921 | FR194921 is a potent, selective and orally active and cross the blood-brain barrier Adenosine A1 antagonist with Ki value of 6.6, 5400 nM for A1, A2A, respectively. FR194921 shows cognitive-enhancing and anxiolytic activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 202646-80-8. Pack Sizes: 5 mg. Product ID: HY-116800. | |
| FR-194921 | FR-194921 is a potent, selective and orally active antagonist for central adenosine A1 receptors that displays high affinity and selectivity for the adenosine A1 receptor (Ki= 2.9 nM) and did not show species differences in binding affinity. Synonyms: 2-(1-methylpiperidin-4-yl)-6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)pyridazin-3-one; FR-194921; FR 194921; FR194921; 2-(1-methyl-4-piperidinyl)-6-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-3(2H)-pyridazinone. Grade: >98%. CAS No. 202646-80-8. Molecular formula: C23H23N5O. Mole weight: 385.46. | |
| FR198248 | FR-198248, a new type of hydroxyl benzaldehyde compound, was isolated from the cultured broth of a fungal strain identified as Aspergillus terreus from morphological characteristics. FR-198248 exhibited anti-influenza virus activity in Madin-Darby canine kidney (MDCK) cells in vitro. Synonyms: FR-198248; 1,5,6,7-Isobenzofurantetrol, 1,3-dihydro-4-methyl-; 197316-54-4; 1-O-Demethyl-FR-202306; 6ZL0C9ER7N; 2,3,4-trihydroxy-6-(hydroxymethyl)-5-methylbenzaldehyde; 364342-83-6; UNII-6ZL0C9ER7N; SCHEMBL1527081; Q27265782. Grade: >98%. CAS No. 197316-54-4. Molecular formula: C9H10O5. Mole weight: 198.17. | |
| FR-202306 | FR-202306 is a synthetic peptide deformylase (PDF) inhibitor. Uses: Peptide deformylase (pdf) inhibitor. Synonyms: FR-202306; FR 202306; FR202306. 3-methoxy-7-methyl-1,3-dihydro-2-benzofuran-4,5,6-triol. Grade: ≥98%. CAS No. 342785-41-5. Molecular formula: C10H12O5. Mole weight: 212.20. | |
| FR-217840 | FR-217840 is a matrix metalloproteinase inhibitor. It can suppress joint destruction. FR217840 may have potential as a novel anti-rheumatic drug. Uses: Anti-rheumatic agent. Synonyms: FR-217840; FR217840; FR 217840. (2S)-1-((5-(4-fluorophenyl)-2-thienyl)sulfonyl)-N-hydroxy-4-(methylsulfonyl)-2-Piperazinecarboxamide. Grade: 98%. CAS No. 848444-16-6. Molecular formula: C16H18FN3O6S3. Mole weight: 463.52. | |
| FR-218944 | FR-218944 is a vasopressin antagonist compound. Synonyms: methanesulfonic acid; 2-methoxy-N-(2-methyl-1H-benzimidazol-4-yl)-4-(2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)benzamide; FR-218944; FR 218944; FR218944. Grade: >98%. CAS No. 233264-02-3. Molecular formula: C28H30N4O6S. Mole weight: 550.63. | |
| FR-221647 | FR-221647 is a non-nucleoside adenosine deaminase inhibitor. Synonyms: 1-(1-hydroxy-4-phenylbutan-2-yl)imidazole-4-carboxamide; FR-221647; FR 221647; FR221647. Grade: >98%. CAS No. 256461-28-6. Molecular formula: C14H17N3O2. Mole weight: 259.3. | |
| FR225659 | FR225659 is originally isolated from Helicomyces sp. No. 19353. It can suppress the gluconeogenesis induced by Glucagon in Primary hepatocytes of rats. Molecular formula: C36H42ClN7O8. Mole weight: 736.21. | |
| FR-229934 | FR-229934 is a Type 5 cyclic nucleotide phosphodiesterase inhibitor. In Feb 2008, preclinical for Erectile dysfunction in Japan was discontinued. Uses: Erectile dysfunction. Synonyms: FR-229934; FR229934; FR 229934. 1-((3,4-dichlorophenyl)methyl)-2-methyl-N-(pentylsulfonyl)-1H-Benzimidazole-6-carboxamide. Grade: 98%. CAS No. 799841-02-4. Molecular formula: C21H23Cl2N3O3S. Mole weight: 468.40. | |
| FR-234938 | FR-234938, with anti-inflammatory property, is a non-nucleoside recombinant human adenosine deaminase enzyme inhibitor. Synonyms: 1-[(3R,4S)-4-hydroxy-1-naphthalen-1-ylpentan-3-yl]imidazole-4-carboxamide; FR-234938; FR 234938; FR234938. Grade: >98%. CAS No. 256461-79-7. Molecular formula: C19H21N3O2. Mole weight: 323.39. | |
| FR-235222 | FR-235222 is an immunosuppressive substance that inhibits mammalian histone deacetylase (HDAC). It is produced by the strain of Acremonium sp. No. 27082. Synonyms: FR 235222; FR235222. Molecular formula: C30H44N4O6. Mole weight: 556.69. | |
| FR236913 | FR236913 is a compoundused in studying chronic lymphocytic leukemia (CLL) and other hematologic malignancies. This targeted therapy inhibits Bruton's tyrosine kinase (BTK) is a key enzyme in the B-cell receptor signaling pathway. By disrupting abnormal B-cell signaling, FR236913 helps control the progression of CLL. Synonyms: 1-[(2R)-4-{6-[(Benzylcarbamoyl)amino]-1H-indol-1-yl}-1-hydroxybutan-2-yl]-1H-imidazole-4-carboxamide. Molecular formula: C24H26N6O3. Mole weight: 446.5. | |
| FR 236924 | FR 236924. Group: Biochemicals. Grades: Purified. CAS No. 28399-31-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| FR 236924 | FR 236924 is a selective PKCε activator with > 7-fold selectivity over other PKC isozymes. FR 236924 promotes glutamate release via presynaptic α7 nicotinic receptors on glutamatergic terminals in vitro and enhances cognition in vivo. It has the potential for the treatment of Alzheimer disease. Synonyms: FR 236924; FR236924; FR-236924; Dcp-LA; 2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid. Grade: ≥99% by HPLC. CAS No. 28399-31-7. Molecular formula: C20H36O2. Mole weight: 308.5. | |
| FR-245 | FR-245. CAS No. 25713-60-4. Molecular formula: C21H6Br9N3O3. Mole weight: 1067.4g/mol. IUPAC Name: 2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine. SMILES: C1=C(C=C(C(=C1Br)OC2=NC(=NC(=N2)OC3=C(C=C(C=C3Br)Br)Br)OC4=C(C=C(C=C4Br)Br)Br)Br)Br. InChI: InChI=1S/C21H6Br9N3O3/c22-7-1-10(25)16(11(26)2-7)34-19-31-20(35-17-12(27)3-8(23)4-13(17)28)33-21(32-19)36-18-14(29)5-9(24)6-15(18)30/h1-6H. |  |
| FR252384 | FR252384 is novel potent antagonists of human neuropeptide Y-Y5 receptor (IC50= 2.3 nM). Synonyms: FR252384; FR 252384; FR-252384; 9-methyl-2-pyridin-3-yl-3,4,5,6-tetrahydrobenzo[2,3]cyclohepta[2,4-b]imidazole; Benzo[3,4]cyclohept[1,2-d]imidazole, 1,4,5,6-tetrahydro-9-methyl-2-(3-pyridinyl)-. CAS No. 447405-11-0. Molecular formula: C18H17N3. Mole weight: 275.35. | |
| FR 252921 | FR 252921 is produced by the strain of Pseudomonas fluorenscens No. 408813. It shows immunosuppressive effect in mice in vivo and in vitro, and has synergistic effect with FK-506. Molecular formula: C29H44N2O5. Mole weight: 500.67. | |
| FR-252922 | FR-252922 is produced by the strain of Pseudomonas fluorenscens No. 408813. It shows immunosuppressive effect in mice in vivo and in vitro, and has synergistic effect with FK-506. Molecular formula: C31H48N2O5. Mole weight: 528.72. | |
| FR-29038 | It is originally isolated from Nocardia uniformis subsp. tsuyamanensis. FR-29038 has anti-Bacillus, Escherichia, Klebsiella, Pseudomonas, Salmonella, Shigella and other family bacteria activities. Synonyms: Antibiotic FR 29038; BRN 3578863; O-{4-[1-Amino-2-({1-[carboxy(4-hydroxyphenyl)methyl]-2-oxoazetidin-3-yl}imino)-2-hydroxyethyl]phenyl}homoserine. CAS No. 59511-12-5. Molecular formula: C23H26N4O8. Mole weight: 486.47. | |
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