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| Product | Description | |
|---|---|---|
| Futibatinib | Futibatinib is an orally bioavailable, selective and irreversible inhibitor of fibroblast growth factor receptors (FGFRs), displaying antineoplastic activity. It inhibits FGFR-mediated signal transduction and tumor cell proliferation. Synonyms: 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1-pyrazolo[3,4-d]pyrimidinyl]-1-pyrrolidinyl]-2-propen-1-one; 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one. Grade: ≥ 98 %. CAS No. 1448169-71-8. Molecular formula: C22H22N6O3. Mole weight: 418.45. |  |
| Futuximab | Futuximab is a chimeric monoclonal antibody directed against EGFR. Futuximab has been used in the research of cancer therapy. Grade: 95%. CAS No. 1310460-85-5. Molecular formula: C6468H10002N1724O2055S46. Mole weight: 146.3 kDa. | |
| Futuximab | Futuximab is a chimeric monoclonal antibody targeting non-overlapping epitopes on EGFR. Futuximab has antineoplastic activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1310460-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99628. |  |
| Fuziline | Fuziline. Group: Biochemicals. Alternative Names: 15-Hydroxyneoline; 15-Epinagarine; Senbusine C. Grades: Plant Grade. CAS No. 80665-72-1. Pack Sizes: 20mg. Molecular Formula: C24H39NO7, Molecular Weight: 453.569. US Biological Life Sciences. |  Worldwide |
| Fuzuloparib | Fuzuloparib is a poly (ADP-ribose) polymerase (PARP) inhibitor potentially for the treatment of solid tumours. Synonyms: 4-({4-fluoro-3-[2-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[1,5-a]pyrazine-7(8H)-carbonyl]phenyl}methyl)phthalazin-1(2H)-one; 1(2H)-Phthalazinone, 4-[[3-[[5,6-dihydro-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl]carbonyl]-4-fluorophenyl]methyl]-; Fuzuopali; SHR-3162; Fuzuloparibum. Grade: ≥98%. CAS No. 1358715-18-0. Molecular formula: C22H16F4N6O2. Mole weight: 472.40. | |
| FW1256 | FW1256 is a phenyl analogue and a slow-releasing hydrogen sulfide (H2S) donor. FW1256 inhibits NF-κB activity and induces cell apoptosis. FW1256 exerts potent anti-inflammatory effects and has the potential for cancer and cardiovascular disease treatment[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 117089-08-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-121955. | |
| FW1256 | Exogenous H2S, as we know, has anti-inflammatory effects both in macrophages and in animal models. FW1256 is a slow release H2S dononr and it is much more potent in cells. FW1256 may be useful for studies of H2S in biology and could also have future therapeutic value in inflammatory conditions. Uses: Anti-inflammation. Synonyms: FW1256; FW-1256; FW 1256. 2-phenyl-3H-benzo[d][1,3,2]oxazaphosphole 2-sulfide. Grade: 98%. CAS No. 117089-08-4. Molecular formula: C12H10NOPS. Mole weight: 247.25. | |
| FX1 | FX1 is a selective inhibitor of B cell lymphoma 6 (BCL6) (IC50 = 35 μM in reporter assays), which can disrupt formation of the BCL6 repression complex, reactivate BCL6 target genes and mimick the phenotype of mice engineered to express BCL6 with corepressor binding site mutations. FX1 also inhibits ABC-DLBCL cells. Synonyms: FX1; FX-1; FX 1. SCHEMBL16323186; CHEBI:133537; AKOS015865677; CS-7688; HY-102027; 3-[(5Z)-5-(5-chloro-2-oxo-1H-indol-3-ylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid. Grade: 99.75 %. CAS No. 1426138-42-2. Molecular formula: C14H9ClN2O4S2. Mole weight: 368.82. | |
| FX-11 | FX-11 is a potent, selective, reversible and competitive lactate dehydrogenase A (LDHA) inhibitor, with a Ki of 8 μM. FX-11 reduces ATP levels and induces oxidative stress, ROS production and cell death. FX-11 shows antitumor activity in lymphoma and pancreatic cancer xenografts[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LDHA Inhibitor FX11. CAS No. 213971-34-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16214. | |
| FX-909 | FX-909 is a covalent peroxisome proliferator-activated receptor gamma (PPARG) inverse agonist. FX-909 can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2924573-90-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153344. | |
| FXR/TGR5 agonist 1 | FXR/TGR5 agonist 1, a dual agonist of FXR and TGR5, can be used to treat fatty liver disease. Synonyms: N-(3-chloro-5-methoxyphenyl)-N-((4-(3-cyano-4-methoxyphenyl)bicyclo[2.2.2]octan-1-yl)methyl)-3-methylisonicotinamide. CAS No. 2677689-72-2. Molecular formula: C31H32ClN3O3. Mole weight: 530.06. | |
| FY26 (complex) | This active moleculr is a Os(II) anticancer drug candidate. It can generate reactive oxygen species and disrupt the redox balance in cancer cells. Using FY26 and nontoxic doses of L-BSO together allows the potentiation of its anticancer activity and inpartantly, it improves the selectivity for cancer cells versus normal fibroblasts. FY26 can shut down a cancer cell by exploiting weaknesses inherent in their energy generation. Uses: Anti-cancer. Synonyms: FY26; FY-26; FY 26. Osmium(1+)?, [N,?N-dimethyl-4-[2-(2-pyridinyl-κN)?diazenyl-κN1]?benzenamine]?iodo[(1,?2,?3,?4,?5,?6-η)?-1-methyl-4-(1-methylethyl)?benzene]?-, hexafluorophosphate(?1-) (1:1). Grade: 98%. CAS No. 1255143-82-8. Molecular formula: C23H28F6IN4OsP. Mole weight: 822.60. | |
| Fz7-21 | Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) is a potent peptide antagonist of FZD7 receptors , selectively binds to FZD7 CRD subclass and alters the conformation of the CRD and the architecture of its lipid-binding groove. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. Fz7-21 impairs the function of FZD7 in Wnt-β-catenin signalling and stem cell function in intestinal organoids[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ac-LPSDDLEFWCHVMY-NH2. CAS No. 2247635-23-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P1454. | |
| Fz7-21 | Fz7-21, a peptide antagonist of Frizzled 7 receptor, selectively binds to Frizzled 7 CRD subclass. Synonyms: FZD7 binding peptide; Ac-Leu-Pro-Ser-Asp-Asp-Leu-Glu-Phe-Trp-Cys-His-Val-Met-Tyr-NH2. Grade: ≥97% by HPLC. CAS No. 2247635-23-8. Molecular formula: C83H114N18O23S2. Mole weight: 1796.05. | |
| FzM1 | FzM1 is a negative allosteric modulator (NAM) of Frizzled receptor FZD4. FzM1 reduces WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=?6.2). FzM1 binds to an allosteric binding site located in intracellular loop 3 (ICL3) of FZD4 and alters the conformation of the receptor, ultimately inhibiting the WNT/β-catenin cascade[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1680196-54-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116553. | |
| FzM1.8 | FzM1.8, derives from FzM1, is an allosteric agonist of FZD4 with pEC50 of 6.4. FzM1.8 binds to FZD4 and activates the WNT/β-catenin pathway, by promoting TCF/LEF transcriptional activity in the absence of any WNT ligand. FzM1.8 stabilizes FZD4 with an increased affinity for heterotrimeric G protein and stimulates the release of the Gβγ subunit that in turn activates PI3K[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2204290-85-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117163. | |
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