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Fexofenadine EP Impurity G is an impurity of Fexofenadine, which is a histamine H1 receptor antagonist used for the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria. Synonyms: Fexofenadine Hydrochloride EP impurity G; 2-[4-[(1RS)-4-[4-(diphenylmethylidene)piperidin-1-yl]-1-hydroxybutyl]phenyl]-2-methylpropanoic acid; Fexofenadine Impurity G; 4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid; Benzeneacetic acid, 4-[4-[4-(diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-. Grade: ≥95%. CAS No. 1187954-57-9. Molecular formula: C32H37NO3. Mole weight: 483.66.
Fexofenadine hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 153439-40-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Fexofenadine hydrochloride
Fexofenadine hydrochloride. CAS No. 138452-21-8. Product ID: ACM138452218. Molecular formula: C32H40ClNO4. Mole weight: 538.1173. Alfa Chemistry - ISO 9001:32057 Certified.
Fexofenadine hydrochloride
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C32H39NO4 · HCl. CAS No. 153439-40-8. Prepack ID 41698981-1g. Molecular Weight 538.12. See USA prepack pricing.
A metabolite of of terfenadine, a H1-Histamine receptor antagonist. Group: Biochemicals. Alternative Names: Carboxyterfenadine, Terfenadinecarboxyl ate. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Fexofenadine Impurity 11
Fexofenadine Impurity 11. Uses: For analytical and research use. CAS No. 169280-21-1. Molecular formula: C14H17ClO3. Mole weight: 268.74. Catalog: APB169280211.
Fexofenadine Impurity 12
Fexofenadine Impurity 12. Uses: For analytical and research use. CAS No. 1038-06-8. Molecular formula: C18H20N2O2. Mole weight: 296.37. Catalog: APB1038068.
Fexofenadine Impurity 13
Fexofenadine Impurity 13. Uses: For analytical and research use. Molecular formula: C16H21ClO3. Mole weight: 296.79. Catalog: APB07930.
Fexofenadine Impurity 14
Fexofenadine Impurity 14. Uses: For analytical and research use. CAS No. 192885-13-5. Molecular formula: C14H19ClO3. Mole weight: 270.75. Catalog: APB192885135.
Fexofenadine Impurity 15
Fexofenadine Impurity 15. Uses: For analytical and research use. CAS No. 169280-25-5. Molecular formula: C14H19ClO2. Mole weight: 254.75. Catalog: APB169280255.
Fexofenadine Impurity 16
Fexofenadine Impurity 16. Uses: For analytical and research use. Molecular formula: C14H21ClO2. Mole weight: 256.77. Catalog: APB07944.
Fexofenadine Impurity 17
Fexofenadine Impurity 17. Uses: For analytical and research use. Molecular formula: C14H20O2. Mole weight: 220.31. Catalog: APB07945.
Fexofenadine Impurity 18
Fexofenadine Impurity 18. Uses: For analytical and research use. Molecular formula: C14H18O3. Mole weight: 234.3. Catalog: APB07941.
Fexofenadine Impurity 19
Fexofenadine Impurity 19. Uses: For analytical and research use. Molecular formula: C15H20O3. Mole weight: 248.32. Catalog: APB07942.
Fexofenadine Impurity 20
Fexofenadine Impurity 20. Uses: For analytical and research use. Molecular formula: C15H21ClO3. Mole weight: 284.78. Catalog: APB07943.
Fexofenadine Impurity 21
Fexofenadine Impurity 21. Uses: For analytical and research use. Molecular formula: C33H41NO4. Mole weight: 515.69. Catalog: APB07940.
Fexofenadine Impurity 22
Fexofenadine Impurity 22. Uses: For analytical and research use. Molecular formula: C21H29NO5. Mole weight: 375.47. Catalog: APB07939.
Fexofenadine Impurity 8
Fexofenadine Impurity 8. Uses: For analytical and research use. Alternative Names: 2-(4-(4-chlorobutanoyl)phenyl)-2-methylpropanenitrile. CAS No. 169032-17-1. Molecular formula: C14H16ClNO. Mole weight: 249.74. Catalog: APB169032171.
Fexofenadine impurity D
An impurity of Fexofenadine. Fexofenadine is a non-sedating antihistamine that selectively antagonizes the histamine H1 receptor with a Ki value of 11 nM and exhibits anti-inflammatory effects. Synonyms: 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-butyn-1-yl]-α,α-dimethyl-benzeneacetic Acid. Grade: > 95%. CAS No. 832088-68-3. Molecular formula: C32H35NO3. Mole weight: 481.64.
Fexofenadine impurity L
An impurity of Fexofenadine. Fexofenadine is a non-sedating antihistamine that selectively antagonizes the histamine H1 receptor with a Ki value of 12 nM and exhibits anti-inflammatory effects. Synonyms: (Z)-4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-buten-1-yl]-α,α-dimethyl-benzeneacetic Acid. Grade: > 95%. Molecular formula: C32H37NO3. Mole weight: 483.66.
Fexofenadine,methyl ester. Alternative Names: FEXOFENADINE, METHYL ESTER. CAS No. 154825-96-4. Product ID: ACM154825964. Molecular formula: C33H41NO4. Mole weight: 515.68. Alfa Chemistry - ISO 9001:32057 Certified.
Fexofenadine N-oxide
An impurity of Fexofenadine, which is a histamine H1 receptor antagonist used for the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria. Synonyms: 4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-oxido-1-piperidinyl]butyl]-α,α-dimethylbenzeneacetic acid. Grade: ≥95%. CAS No. 1422515-52-3. Molecular formula: C32H39NO5. Mole weight: 517.67.
Fexofenadine Related Compound A
Fexofenadine Related Compound A. Uses: For analytical and research use. CAS No. 76811-98-8. Mole weight: 499.64. Catalog: AP76811988.
Fexofenadine Related Compound C
Fexofenadine Related Compound C. Uses: For analytical and research use. CAS No. 185066-37-9 (free base). Mole weight: 494.11. Catalog: ALP185066379.
Fexofenadine USP Related Compound B
Fexofenadine USP Related Compound B is an impurity of Fexofenadine, which is a histamine H1 receptor antagonist used for the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria. Synonyms: USP Fexofenadine Related Compound B; 3-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl benzeneacetic acid hydrochloride monohydrate; 2-(3-{1-Hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid hydrochloride monohydrate; Fexofenadine EP impurity B hydrochloride monohydrate; Benzeneacetic acid, 3-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-, hydrochloride, hydrate (1:1:1); 2-[3-[(1RS)-1-Hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl]phenyl]-2-methylpropanoic Acid Hydrochloride Monohydrate; 2-[3-(1-Hydroxy-4-{4-[hydroxy(diphenyl)methyl]-1-piperidinyl}butyl)phenyl]-2-methylpropanoic acid hydrochloride hydrate. Grade: ≥95%. Molecular formula: C32H39NO4.HCl.H2O. Mole weight: 556.13.
Fezagepras sodium
Fezagepras sodium is an orally active GPR40 agonist, as well as an antagonist or inverse agonist of GPR84, with anti-fibrotic, anti-inflammatory and anti-proliferative effects. It reduces fibrosis in the renal, liver and pancreas. Synonyms: Setogepram sodium; PBI-4050 sodium; 3-Pentylbenzenacetic acid sodium salt; Benzeneacetic acid, 3-pentyl-, sodium salt (1:1). Grade: ≥95%. CAS No. 1254472-97-3. Molecular formula: C13H17NaO2. Mole weight: 228.26.
Fezagepras sodium
Fezagepras (Setogepram) sodium acts as an orally active agonist for GPR40 and as an antagonist or inverse agonist for GPR84[1]. Fezagepras sodium decreases renal, liver and pancreatic fibrosis[1][2]. Fezagepras sodium exerts anti-fibrotic, anti-inflammatory and anti-proliferative actions[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Setogepram sodium; PBI-4050 sodium. CAS No. 1254472-97-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100775.
Fezakinumab
Fezakinumab (ILV 094) is an anti-IL-22 monoclonal antibody. Fezakinumab inhibits IL-22 signal transduction, and regulates the JAK1/STAT3 pathway as well as apoptotic proteins. Fezakinumab alleviates airway remodeling, alveolar enlargement and inflammatory cell infiltration in lung tissues. Fezakinumab reduces the levels of neutrophils, lymphocytes, eosinophils and macrophages in lung tissues. Fezakinumab can be used in the research of chronic obstructive pulmonary disease and skin diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ILV 094. CAS No. 1007106-86-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99244.
Fezakinumab
Fezakinumab is a human monoclonal antibody that targets interleukin-22. Fezakinumab has been developed for the treatment of psoriasis and rheumatoid arthritis. Synonyms: ILV 094; ILV-094; ILV094. CAS No. 1007106-86-6.
Fezolinetant is a neurokinin 3 receptor (NK3R) antagonist used to treat sex hormone-related diseases. Synonyms: Fezolinetant; 1629229-37-3; ESN364ESN-364; UNII-83VNE45KXX. Grade: ≥98% by HPLC. CAS No. 1629229-37-3. Molecular formula: C16H15FN6OS. Mole weight: 358.4.
Fezolinetant
Fezolinetant is an antagonist of the neurokinin 3 receptor (NK3R), used for the treatment of menopausal hot flushes. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ESN-364. CAS No. 1629229-37-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19632.
Fezolinetant
Fezolinetant is an antagonist of the neurokinin 3 receptor (NK3R), used for the treatment of menopausal hot flushes. Category: Active pharmaceutical ingredients. Synonyms: ESN-364. CAS No. 1629229-37-3. Product ID: API1629229373. Molecular formula: C16H15FN6OS. Mole weight: 358.39.
FF-10101
FF-10101 is a FLT3 inhibitor that shows excellent efficacy against AML cells with FLT3 mutations. Uses: Protein kinase inhibitors. Synonyms: FF-10101; 1472797-69-5; (S,E)-N-(1-((5-(2-((4-Cyanophenyl)amino)-4-(propylamino)pyrimidin-5-yl)pent-4-yn-1-yl)amino)-1-oxopropan-2-yl)-4-(dimethylamino)-N-methylbut-2-enamide; 7V7IHI0SYG; UNII-7V7IHI0SYG; Ff-10101-01; 2-Butenamide, N-((1S)-2-((5-(2-((4-cyanophenyl)amino)-4-(propylamino)-5-pyrimidinyl)-4-pentyn-1-yl)amino)-1-methyl-2-oxoethyl)-4-(dimethylamino)-N-methyl-, (2E)-; CHEMBL4650283; SCHEMBL15584726; SCHEMBL16443760; BDBM397428; BCP23613; s8899; AKOS040733173; US9987278, Compound Reference 38; HY-109584; CS-0032038; FF 10101; FF10101; D87147; (E)-N-[(2S)-1-[5-[2-(4-cyanoanilino)-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxopropan-2-yl]-4-(dimethylamino)-N-methylbut-2-enamide. CAS No. 1472797-69-5. Molecular formula: C29H38N8O2. Mole weight: 530.66.
FF-10102-01
FF-10102-01 is a novel and selective inhibitor of spleen tyrosine kinase (Syk). Syk plays a role in downstream pathways in signaling from B-cell receptor (BCR) in B cells and Fc-gamma receptors in macrophages. FF-10102-01 exhibits an inhibitory effect on the phosphorylation of SLP76 and ERK1/2 in THP-1 cells, and on inflammation as well as thrombocytopenia. FF-10102-01 is promisingly to be a drug used for the treatment of autoimmune disease. Uses: The potential treatment of autoimmune disease.
FF-10502
FF-10502 is a pyrimidine nucleoside antimetabolite and a structural analog of Gemcitabine. This compound effectively inhibits DNA polymerase α and β, demonstrating potent anticancer activity by targeting dormant cells. Category: Active pharmaceutical ingredients. CAS No. 184302-49-6. Product ID: API184302496. Molecular formula: C9H12FN3O3S. Mole weight: 261.27.
FFAGLDD amine salt
FFAGLDD amine salt is an MMP9 selective cleavage peptide, which was used for cytosolic delivery of Doxorubi-cin (DOX). CAS No. 2703745-71-3. Molecular formula: C37H52N8O12. Mole weight: 800.85.
FFN 102 mesylate
FFN 102 mesylate is a selective dopamine transporter (DAT) and VMAT2 substrate with no significant binding to a panel of 38 CNS receptors. Synonyms: FFN 102 mesylate; FFN102 mesylate; FFN-102 mesylate; 4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one methanesulfonate. Grade: ≥99% by HPLC. CAS No. 1883548-92-2. Molecular formula: C11H11N2ClO3.CH3SO3H. Mole weight: 335.76.
FFN 200 dihydrochloride
FFN 200 dihydrochloride is a selective fluorescent VMAT2 substrate that traces exocytosis in dopaminergic neuronal cell culture and brain tissue. Synonyms: FFN 200 dihydrochloride; FFN200 dihydrochloride; FFN-200 dihydrochloride; 4-(2-Aminoethyl)-7-amino-2H-1-benzopyran-2-one dihydrochloride. Grade: ≥98% by HPLC. CAS No. 2080306-27-8. Molecular formula: C11H14Cl2N2O2. Mole weight: 277.15.
FFN 206 dihydrochloride
FFN 206 dihydrochloride is a fluorescent VMAT2 substrate (IC50 app = 1.15 μM) that detects VMAT2 activity in intact cells. Synonyms: FFN 206 dihydrochloride; FFN206 dihydrochloride; FFN-206 dihydrochloride; 4-(2-Aminoethyl)-7-(methylamino)-2H-1-benzopyran-2-one dihydrochloride. Grade: ≥99% by HPLC. CAS No. 1883548-88-6. Molecular formula: C12H14N2O2.2HCl. Mole weight: 291.17.
FFN 206 dihydrochloride
FFN 206 dihydrochloride, a fluorescent probe, is used as an excellent Vesicular Monoamine Transporter 2 (VMAT2) substrate with an apparent Km of 1.16 μM. FFN 206 dihydrochloride is capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1883548-88-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-110334.
FFN246
FFN246 is a fluorescent, dual substrate of serotonin transporter (SERT) probe and vesicular monoamine transporter 2 (VMAT2) with excitation and emission spectra 392/427 nm. FFN246 can be used for labeling serotonergic neurons in mouse brain tissue through SERT-dependent accumulation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2210244-83-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149170.
FFN511
FFN511 is a potent fluorescent false neurotransmitters (FFNs) that targets neuronal vesicular monoamine transporter 2 (VMA T2). FFN511 inhibits serotonin binding to VMA T2-containing membranes with an IC50 of 1 μM. FFN511 directly images the dynamics of release during exocytosis, can be used to label dopamine terminals in live cortical-striatalacute slices[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1004548-96-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103465.
FFN 511
FFN 511 is a fluorescent false neurotransmitter (FFN) targeting neuronal vesicular monoamine transporter (VMAT) 2 to inhibit serotonin binding to VMAT2 (IC50 = 1 μM). Synonyms: FFN 511; FFN511; FFN-511; 9-(2-Aminoethyl)-2,3,6,7-tetrahydro-1H,5H,11H-[1]-benzopyrano[6,7,8-ij]quinolizin-11-one. Grade: ≥99% by HPLC. CAS No. 1004548-96-2. Molecular formula: C17H20N2O2. Mole weight: 284.35.
FG-2216
FG-2216, also known as YM311, is an orally bioavailable HIF-prolyl hydroxylase inhibitor. FG-2216 induced significant and reversible Epo induction in vivo. Synonyms: FG 2216; FG2216; YM311; YM-311; YM 311; N-[(1-Chloro-4-hydroxyisoquinolin-3-YL)carbonyl]glycine. Grade: 98%. CAS No. 223387-75-5. Molecular formula: C12H9ClN2O4. Mole weight: 280.66.
FG-2216
FG-2216 (IOX3) is a potent and orally active inhibitor of HIF prolyl hydroxylase-2 (PHD2), with an IC50 of 3.9 μM. FG-2216 induces robust erythropoietin and modest fetal hemoglobin in vivo[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IOX3; YM311. CAS No. 223387-75-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15641.
FG-3019
FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pamrevlumab; Anti-Human CTGF Recombinant Antibody. CAS No. 946415-13-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99288.
FG 7142
FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 (ZK 39106; LSU-65) can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZK 39106; LSU-65. CAS No. 78538-74-6. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-100991.
FG 7142
FG 7142 is a benzodiazepine inverse agonist and anxiogenic agent. FG 7142 increases tyrosine hydroxylation and upregulates β-adrenoceptors in mouse cerebral cortex. Uses: Anxiogenic agent. Synonyms: FG 7142; FG7142; FG-7142; N-Methyl-β-carboline-3-carboxamide. Grade: ≥99% by HPLC. CAS No. 78538-74-6. Molecular formula: C13H11N3O. Mole weight: 225.25.
FG 7142
FG 7142. Group: Biochemicals. Grades: Purified. CAS No. 78538-74-6. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
FG8119
FG8119 is a novel benzodiazepine agonist. Synonyms: 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one; 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6-dihydro-5-methyl-6-oxo-4H-imidazo(1,5a)(1,4)benzodiazepine; COMeIB; FG 8119; FG-8119. CAS No. 106447-61-4. Molecular formula: C17H15N5O2. Mole weight: 321.33.
FGF-401
FGF-401 is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4) (IC50 = 1.9 nM) developed for the treatment of solid tumor. Synonyms: FGF401; FGF-401; FGF 401; roblitinib; N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide. CAS No. 1708971-55-4. Molecular formula: C25H30N8O4. Mole weight: 506.56.
FGFR1/DDR2 inhibitor 1 is an orally active fibroblast growth factor receptor 1 (FGFR1) and discoindin domain receptor 2 (DDR2) inhibitor, with IC50s of 31.1 and 3.2 nM, respectively. It has antitumor activity. Synonyms: 3-(3-(1-Cyclopropyl-1H-pyrazol-4-yl)-1H-indazol-6-yl)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide; Benzamide, 3-[3-(1-cyclopropyl-1H-pyrazol-4-yl)-1H-indazol-6-yl]-4-methyl-N-[3-(trifluoromethyl)phenyl]-. Grade: ≥95%. CAS No. 2308497-58-5. Molecular formula: C28H22F3N5O. Mole weight: 501.50.
FGFR1 inhibitor-2
FGFR1 inhibitor-2, an inhibitor of FGFR1 (IC50 = 4.55 μM in MDA-MB-231 cells), is used in the study of metastatic triple-negative breast cancer. Synonyms: Urea, N-[5,5-bis(4-fluorophenyl)pentyl]-N'-[4-nitro-3-(trifluoromethyl)phenyl]-. CAS No. 2410612-08-5. Molecular formula: C25H22F5N3O3. Mole weight: 507.45.
FGFR2-IN-2
FGFR2-IN-2 (Compound 38) is a selective FGFR2 inhibitor with IC50s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2677709-81-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145231.
FGFR3-IN-5
FGFR3-IN-5 is a potent and selective FGFR3 inhibitor with IC50 values of 3, 44, and 289 nM for FGFR3, FGFR2, and FGFR1, respectively. FGFR3-IN-5 can be used in research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2446664-72-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148779.
FGFR4-IN-1
FGFR4-IN-1 is a potent and selective FGFR4 inhibitor with potential for the treatment of gastric cancer. Synonyms: N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((3-oxomorpholino)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide; FGFR4-IN-1; FGFR4-IN1; FGFR4-IN 1. CAS No. 1708971-72-5. Molecular formula: C24H27N7O5. Mole weight: 493.52.
FGFR4-IN-4
FGFR4-IN-4 is an inhibitor of FGFR4 with antitumor activity. (Extracted from patent WO2018113584A1). Synonyms: N-((3R,4S)-4-((6-(2,6-Dichloro-3,5-dimethoxyphenyl)-8-(4-methoxypiperidin-1-yl)pyrido[3,4-d]pyrimidin-2-yl)amino)tetrahydrofuran-3-yl)acrylamide; 2-Propenamide, N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(4-methoxy-1-piperidinyl)pyrido[3,4-d]pyrimidin-2-yl]amino]tetrahydro-3-furanyl]-. Grade: ≥95%. CAS No. 2230973-67-6. Molecular formula: C28H32Cl2N6O5. Mole weight: 603.50.
FGFR4-IN-5
FGFR4-IN-5, a potent and selective covalent FGFR4 inhibitor (IC50 = 6.5 nM), has strong antitumor activity in vivo and can be used in hepatocellular carcinoma studies. Synonyms: 2-Propenamide, N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-7,8-dihydro-8-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]tetrahydro-3-furanyl]-; N-[(3R,4S)-4-{[6-(2,6-Dichloro-3,5-dimethoxyphenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}tetrahydro-3-furanyl]acrylamide. Grade: ≥98%. CAS No. 1628793-01-0. Molecular formula: C23H23Cl2N5O5. Mole weight: 520.37.
FGFR-IN-1
FGFR-IN-1 is a potent inhibitor of FGFR with IC50s of <100 nM for FGFR1, FGFR2 and FGFR3, respectively. (Extracted from patent US20130338134A1, example 219). Synonyms: 2H-Pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one, 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-1,3,4,7-tetrahydro-8-(hydroxymethyl)-7-(phenylsulfonyl)-; 3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(hydroxymethyl)-7-(phenylsulfonyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one. Grade: ≥95%. CAS No. 1513860-41-7. Molecular formula: C26H24F2N4O6S. Mole weight: 558.55.
FGF@-STAB - Skin Care Active Ingredient / Anti-Wrinkle
Enantis’ FGF2-STAB® – Stabilized Fibroblast Growth Factor 2 Polypeptide. FGF2-STAB® is a next-generation, patented growth factor developed by Enantis to address one of formulation’s greatest challenges — instability. Unlike traditional FGF2, which rapidly degrades, FGF2-STAB® features a novel peptide sequence engineered for outstanding thermal and biological stability, ensuring longer shelf life, easier formulation, and superior performance. FGF2-STAB® enhances the stability of native FGF2, a key signaling peptide involved in skin regeneration pathways. While isolated FGF2 loses efficacy over time, Enantis’ HYPERSTABLE Growth Factors deliver sustained activity and reliability for advanced cosmetic applications.
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FGH10019
FGH10019 is a novel sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM, 5-10 times lower than the IC50 of fatostatin (~10 μM). Synonyms: FGH10019; FGH 10019; FGH-10019. Grade: >98%. CAS No. 1046045-61-7. Molecular formula: C18H19N3O2S2. Mole weight: 373.49.
FGH96 Alloy Powder
FGH96 alloy has good corrosion resistance and oxidation resistance below 980 °C, high strength below 800 °C, and good relaxation resistance below 540 °C.
FGI-106
FGI-106, a potent and broad-spectrum inhibitor, has inhibitory activity against a variety of viruses with EC50s of 100, 800 and 400-900 nM against Ebola, Rift Valley and Dengue Fever viruses, respectively. It also inhibits non-hemorrhagic fever viruses HCV and HIV-1 with EC50s of 200 and 150 nM, respectively. Synonyms: Quino[8,7-h]quinoline-1,7-diamine, N1,N7-bis[3-(dimethylamino)propyl]-3,9-dimethyl-; N,N'-Bis[3-(dimethylamino)propyl]-3,9-dimethylquinolino[8,7-h]quinoline-1,7-diamine; NSC-306365; N1,N7-Bis[3-(dimethylamino)propyl]-3,9-dimethylquino[8,7-h]quinoline-1,7-diamine. Grade: ≥95%. CAS No. 501081-38-5. Molecular formula: C28H38N6. Mole weight: 458.64.
FGIN 1-27
FGIN 1-27, an indoleacetamide, is a specific peripheral benzodiazepine receptor (PBR) ligand with a Ki of 5.0 nM. FGIN 1-27 can penetrate the blood brain barrier (BBB). FGIN 1-27 inhibits the onset of Isoniazid-induced convulsions[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 142720-24-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101059.
FGIN-1-27
FGIN-1-27 is a high affinity agonist of mitochondrial benzodiazepine receptors (PBR) binding to benzodiazepine receptors on mitochondrial membranes. FGIN-1-27 indirectly potentiates GABAA receptor signaling to exhibit anticonvulsant, anxiolytic, and sedative activity in both animal and clinical models. Synonyms: FGIN-1-27; FGIN 1 27; FGIN-1 27; FGIN 1-27; FGIN127; N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide; 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide. Grade: ≥98% by HPLC. CAS No. 142720-24-9. Molecular formula: C28H37FN2O. Mole weight: 436.61.
FGIN-1-27
FGIN-1-27. Group: Biochemicals. Grades: Purified. CAS No. 142720-24-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.