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| Product | Description | |
|---|---|---|
| GYKI-16638 | GYKI-16638 is Potassium channel and Sodium channel antagonist originated by Nonindustrial source. It is a novel antiarrhythmic agent. Uses: Arrhythmias. Synonyms: GYKI-16638; GYKI 16638; GYKI16638; N-(4-(2-((1-(2,6-dimethoxyphenoxy)propan-2-yl)(methyl)amino)ethyl)phenyl)methanesulfonamide. Grade: 98%. CAS No. 778564-77-5. Molecular formula: C21H30N2O5S. Mole weight: 422.54. |  |
| GYKI-16638 HCl | GYKI-16638 is a novel antiarrhythmic agent, shows combined Class IB and Class III antiarrhythmic properties, resembling the electrophysiological manifestation seen after chronic amiodarone treatment. Uses: A novel antiarrhythmic agent. Synonyms: GYKI-16638 HCl; GYKI 16638 HCl; GYKI16638 HCl; N-[4-[2-[1-(2,6-dimethoxyphenoxy)propan-2-yl-methylamino]ethyl]phenyl]methanesulfonamide; hydrochloride. Grade: ≥98%. CAS No. 307556-59-8. Molecular formula: C21H31ClN2O5S. Mole weight: 458.998. | |
| GYKI-20238 | GYKI-20238 is a thiazolidine compound with anti-amnesic activity. Uses: Anti-amnesic. Synonyms: GYKI-20238; GYKI20238; GYKI 20238; GYKI-20,238; GYKI20,238; GYKI 20,238. 2-Methylimino-3-(2,6-dichlorophenyl)-4-methylthiazolidine. Grade: ≥96%. CAS No. 30725-74-7. Molecular formula: C11H12Cl2N2S. Mole weight: 274.01. | |
| GYKI-23107 | GYKI-23107 is an antiarrhythmic agent with local anaesthetic activity. Uses: Antiarrhythmic agent. Synonyms: N1-(2,6-dimethylphenyl)-N2,N2-dimethylpropane-1,2-diamine; GYKI-23107; GYKI 23107; GYKI23107. Grade: 98%. CAS No. 83843-49-6. Molecular formula: C13H22N2. Mole weight: 206.33. | |
| GYKI-23107 dihydrochloride | GYKI-23107 is an antiarrhythmic agent with local anaesthetic activity. Uses: Antiarrhythmic agent. Synonyms: GYKI-23107 dihydrochloride; GYKI 23107 dihydrochloride; GYKI23107 dihydrochloride; 83843-49-6 (free base); N1-(2,6-dimethylphenyl)-N2,N2-dimethylpropane-1,2-diamine dihydrochloride. Grade: 98%. CAS No. 83843-39-4. Molecular formula: C13H24Cl2N2. Mole weight: 279.25. | |
| GYKI-46903 HCl | GYKI-46903 is a Muscarinic M3 receptor and Serotonin 3 receptor antagonist. In displacement studies, the pIC50 values of GYKI-46903 against [3H]granisetron binding to rat cerebral cortex membranes were 6.91. No development was reported for the treatment of Cognition disorders, Nausea and vomiting. Uses: Cognition disorders; nausea and vomiting. Synonyms: GYKI-46903; GYKI 46903; GYKI46903; GYKI-46,903; GYKI 46,903; GYKI46,903; (4R,5R)-6-(4-fluorophenyl)-1-azabicyclo[3.3.1]non-6-en-4-yl propionate hydrochloride. Grade: 98%. CAS No. 142999-59-5. Molecular formula: C17H21ClFNO2. Mole weight: 325.81. | |
| GYKI-47261 | GYKI-47261 is a non-competitive AMPA receptor antagonist (IC50 = 2.5 μM) and a CYP2E1 inducer. GYKI-47261 shows broad spectrum anticonvulsive activity and neuroprotective effects in vivo. Synonyms: 4-(8-chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-yl)aniline; GYKI 47261; GYKI47261; GYKI-47261. Grade: >99 %. CAS No. 220445-20-5. Molecular formula: C18H15ClN4. Mole weight: 322.796. | |
| Gyki 47261 dihydrochloride | Gyki 47261 dihydrochloride. Alternative Names: GYKI 47261 DIHYDROCHLORIDE, GYKI 47261, CTK8E9492, (Z)-4-(8-chloro-2-methyl-11H-benzo[e]imidazo[1,2-b][1,2]diazepin-6-yl)aniline dihydrochloride, 220445-20-5. CAS No. 1217049-32-5. Purity: >99 %. Product ID: ACM1217049325. Molecular formula: C18H15ClN4.2HCl. Mole weight: 395.71. IUPAC Name: 4-(8-chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-yl)aniline;dihydrochloride. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| GYKI 47261 dihydrochloride | This active molecular is Non-competitiv a AMPA antagonist with IC50 value of 2.5 μM. GYKI-47261 is also a CYP2E1 inducer. GYKI-47261 showed broad spectrum of anticonvulsive and really good neuroprotective effect in vivo. AMPA and NMDA receptors have been implicated in the regulation of corticostriatal synaptic efficacy which abundantly expressed on striatal medium spiny neurons. In 2000, preclinical development for Epilepsy in Hungar was on-going, but no development was reported yet. Uses: Epilepsy; parkinson's disease; stroke. Synonyms: GYKI 47261 dihydrochloride; GYKI47261 dihydrochloride; GYKI-47261 dihydrochloride; 4-(8-chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-yl)aniline; dihydrochloride; 220445-20-5 (free base). Grade: 98%. CAS No. 1217049-32-5. Molecular formula: C18H17Cl3N4. Mole weight: 395.71. | |
| GYKI 47261 dihydrochloride | GYKI 47261 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1217049-32-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| GYKI-52466 | GYKI-52466 is a non-competitive AMPA receptor antagonist. It belongs to 2,3-benzodiazepine that acts as an ionotropic glutamate receptor antagonist. It has anticonvulsant and neuroprotective properties. It is an orally-active anticonvulsant and skeletal muscle relaxant. It also was found to have therapeutic potential for cocaine addiction treatment. Uses: Gyki-52466 is an orally-active anticonvulsant and skeletal muscle relaxant. it also was found to have therapeutic potential for cocaine addiction treatment. Synonyms: 4-(8-Methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline; GYKI-52466; GYKI52466; GYKI 52466; GYKI-5,2466; GYKI52,466; GYKI 52,466. Grade: >99 %. CAS No. 102771-26-6. Molecular formula: C17H15N3O2. Mole weight: 293.33. | |
| GYKI 52466 dihydrochloride | GYKI 52466 dihydrochloride, a muscle relaxant and anticonvulsant agent with good blood-brain barrier permeability, is a potent, selective, orally active and non-competitive antagonist of kainate- and AMPA-activated currents with IC50s of 7.5 and 11 μM, respectively. It has no activity against N-methyl-D-aspartate (NMDA) or γ-aminobutyric acid responses. Synonyms: 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-benzenamine dihydrochloride; Benzenamine, 4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-, hydrochloride (1:2). Grade: ≥95%. CAS No. 2319722-40-0. Molecular formula: C17H17Cl2N3O2. Mole weight: 366.24. | |
| GYKI 52466 dihydrochloride | GYKI 52466 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 102771-26-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GYKI 52466 dihydrochloride | GYKI 52466 dihydrochloride is an orally active, highly selective and noncompetitive AMPA/kainate receptor antagonist with the IC50 values of 7.5 and 11μM, respectively. GYKI 52466 dihydrochloride has good blood brain barrier permeability and anticonvulsant effect. GYKI 52466 dihydrochloride can be used in Parkinson's disease research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2319722-40-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103234A. |  |
| GYKI 52466 hydrochloride | GYKI 52466 hydrochloride, a muscle relaxant and anticonvulsant agent with good blood-brain barrier permeability, is a potent, selective, orally active and non-competitive antagonist of kainate- and AMPA-activated currents with IC50s of 7.5 and 11 μM, respectively. It has no activity against N-methyl-D-aspartate (NMDA) or γ-aminobutyric acid responses. Synonyms: 4-(8-Methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline hydrochloride; 1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride; Benzenamine, 4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-, hydrochloride (1:1). Grade: ≥95%. CAS No. 192065-56-8. Molecular formula: C17H16ClN3O2. Mole weight: 329.78. | |
| GYKI 52466 Hydrochloride (1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine Hydrochloride, GYKI-52,466, GYK I52466) | A potent negative allosteric modulator selective for AMPA glutamate receptors (IC50 = 10-20uM) over kainate (IC50 ~450uM) and nMDA (IC50 >> 50uM) receptors. Commonly used as neuroprotectant, anticonvulsant, and skeletal muscle relaxant. Biologically viable admitted orally or systematically. Group: Biochemicals. Grades: Highly Purified. CAS No. 102771-26-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GYKI 53655 | GYKI 53655 is a selective AMPA receptor antagonist with anticonvulsant activity. Synonyms: GYKI 53655; GYKI53655; GYKI-53655; 5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide. Grade: 99%. CAS No. 143692-18-6. Molecular formula: C19H20N4O3. Mole weight: 352.39. | |
| GYKI 53655 hydrochloride | GYKI 53655 hydrochloride is a non-competitive AMPA and kainate receptor antagonist displaying anticonvulsant activity. It also acts as a blocker of GluK3 homomeric receptors (IC50 = 63 μM) and GluK2b(R)/GluK3 heteroreceptors (IC50 = 32 μM) at high concentrations. GYKI 53655 prolongs the survival time after MgCl2- induced global cerebral ischemia. Synonyms: GYKI53655 Hydrochloride; GYKI53655 HCl; GYKI53655; GYKI 53655; GYKI-53655. LY 300168 hydrochloride; LY300168 hydrochloride; LY-300168 hydrochloride; 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride; 5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide hydrochloride. Grade: ≥99% by HPLC. CAS No. 143692-48-2. Molecular formula: C19H20N4O3.HCl. Mole weight: 388.85. | |
| GYKI 53655 Hydrochloride | A potent negative allosteric modulator selective for AMPA glutamate receptors (IC50 = 6 and 5uM for GluA1 and GluA4, respectively) over kainate receptors (IC50 = 63 and 32uM for GluK3 and GluK2b/GluK3 receptors. Used as neuroprotectant and anticonvulsant, and a valuable tool for the study of AMPA receptor-mediated processes in vivo. Group: Biochemicals. Alternative Names: LY 300168, GYKI-53655 Hydrochloride, AMPA Glutamate Receptor Antagonist, GYKI 53655 Hydrochloride, 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine Hydrochloride. Grades: Highly Purified. CAS No. 143692-48-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GYKI 53784 | GYKI-53784, a dioxolbenzene derivative, has been found to be a AMPA receptor antagonist that could block excitotoxicity and decrease auditory nerve activity at some extent. Synonyms: GYKI-53784; GYKI53784; GYKI 53784; LY 303070; LY-303070; LY303070; 7H-1,3-Dioxolo(4,5-h)(2,3)benzodiazepine-7-carboxamide, 8,9-dihydro-5-(4-aminophenyl)-N,8-dimethyl-, (R)-; UNII-91N8O25H4L; AC1MIO7T. Grade: 98%. CAS No. 161832-71-9. Molecular formula: C19H20N4O3. Mole weight: 352.39. | |
| Gymnema Extract (Ratio) | Gymnema Extract (Ratio). Group: Others. Purity: 4:1~20:1. Gymnema Extract (Ratio). Cat No: EXTW-070. |  |
| Gymnema Extract (Standard) | Gymnema (Gymnema sylvestre) is an herb native to the tropical forests of southern and central India and Sri Lanka. Applications: Gymnema extract is one of the major botanicals being administered for those suffering from diabetes, in boosting insulin levels and controlling healthy blood sugar levels. it has unique property to directly mask the tongue's ability to taste sweet foods, at the same time suppresses glucose absorption from the intestine. Group: Others. CAS No. 122168-40-5. Purity: 25.0% 75.0% Gymnemic acid HPLC. Mole weight: 806.445257 g/mol. Gymnema Extract (Standard); 122168-40-5; C43H66O14. Cat No: EXTW-004. | |
| Gymnemagenin | Gymnemagenin. Group: Biochemicals. Grades: Plant Grade. CAS No. 22467-07-8. Pack Sizes: 10mg. Molecular Formula: C30H50O6, Molecular Weight: 506.72. US Biological Life Sciences. | Worldwide |
| Gymnemagenin | Gymnemagenin is a triterpenoid isolated from G. sylvestre. Gymnemagenin is an agent for diabetes and obesity and also possesses antiviral properties[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 22467-07-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2268. | |
| Gymnema Sylvestre Extract | Gymnema Sylvestre Extract. Applications: Used for health care products, dietary supplements, reduce hypoglycemic activity. Group: Others. Synonyms: Gymnema Sylvestre Extract; 1399-64-0; Gymnema sylvestre ?Retz.? Schult. CAS No. 1399-64-0. Purity: 25%, 75% Gymnemic Acid By UV. Appearance: Brown yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Leaf. Species: Gymnema sylvestre ?Retz.? Schult. Gymnema Sylvestre Extract; 1399-64-0; Gymnema sylvestre ?Retz.? Schult.; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-098. | |
| Gymnema Sylvestre Extract | Gymnema Sylvestre Extract. CAS No. 90045-47-9. Purity: 25% gymnemic acid. Product ID: CI-NAT-90045479. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Gymnema Sylvestre Extract 75% | Gymnema Sylvestre Extract 75%. |  CA, FL & NJ |
| Gymnemic acid | Gymnemic acid Inhibitor. Uses: Scientific use. Product Category: TN1718. CAS No. 122168-40-5. |  |
| Gymnemic acid I | Gymnemic acid I is a bioactive triterpene saponin found in Gymnema sylvestre. Gymnemic acid I is an antisweetness inhibitor via human sweet receptor type 1 receptor 2 (T1R2) and T1R3. Gymnemic acid I is a ribosomal protein biosynthesis inhibitor. Gymnemic acid I has antidiabetic effects. Gymnema acid I induces autophagy-protected MIN-6 cells from apoptosis under high glucose stress by inhibiting the phosphorylation activity of mTOR[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 122168-40-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2541. | |
| Gymnemic acid I | Gymnemic acid I. Alternative Names: (+)-Gymnemic Acid I. CAS No. 122168-40-5. Purity: >95.0%. Product ID: FFC-AR-122168405. Molecular formula: C43H66O14. Mole weight: 806.98. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Gymnemic Acid I | Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 122168-40-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Gymnestrogenin | Gymnestrogenin. Group: Biochemicals. Grades: Plant Grade. CAS No. 19942-02-0. Pack Sizes: 5mg. Molecular Formula: C30H50O5, Molecular Weight: 490.73. US Biological Life Sciences. | Worldwide |
| Gymnin | Gymnin is a potent defensin-like antifungal peptide from the Yunnan bean (Gymnocladus chinensis Baill). Gymnin exerts antifungal activity against F.oxysporum and M.arachidicola, with an IC50 of 2 μM for the former fungus and 10 μM, respectively. It inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase. | |
| Gymnoside I | Gymnoside I (compound 1) is a glycosidoxybenzyl 2-isobutylmalic acid. Gymnoside I shows antiallergic activity in passive cutaneous allergic reaction (PCA) in mice. Gymnoside I can be used in research to research asthma, neurasthenia and chronic hepatitis[1]. Uses: Scientific research. Category: Natural products. CAS No. 899430-01-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N12127. | |
| Gym Rubber | Gym rubber is a high-density closed-cell foam with a medium feel and good resistance to oils and fuels. It is technically known as polyvinyl chloride/nitrile rubber/neoprene (PVC/NBR/CR) and is formally known as Ensolite IG2 by Armacell. |  |
| Gynostemma Extract | Gynostemma extract is prepared from the leaf of Gynostemma, a cucurbitaceous plant belongs to perennial grass nature lianas grows in the southeastern regions of China. Gynostemma pentaphyllum extract contains more than 80 different saponins, so is also known as southern ginseng. Gynostemma extract gypenoside is widely used as an anti aging supplement, or a tonic to treat bronchitis, strengthen the body, reduce fatigue, and reinforce overall health. Group: Others. Gynostemma Extract; Gynostemma Pentaphyllum Thunb. Cat No: EXTC-023. | |
| Gynostemma Pentaphyllum Extract (Ratio) | Gynostemma Pentaphyllum Extract (Ratio). Group: Others. Purity: 4:1~20:1. Gynostemma Pentaphyllum Extract (Ratio). Cat No: EXTW-037. | |
| Gypenoside I | Gypenoside I is an intricate phytochemical abundantly occurring in the plant known as Gynostemma Pentaphyllum. The multifaceted potential of Gypenoside I resides in its astonishingly promising capacity to potentially study a diverse array of maladies, which encompass the realms of cancer, diabetes, inflammation, as well as cardiovascular disorders. Synonyms: (3β,12β)-20-[(6-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→6)-O-[β-D-glucopyranosyl-(1→2)]-β-D-glucopyranoside. CAS No. 85889-20-9. Molecular formula: C60H102O27. Mole weight: 1255.44. | |
| Gypenoside L | Gypenoside L is a saponin that can be found in Gynostemma pentaphyllum. Gypenoside L increases the SA-β-galactosidase activity, promotes the production of senescence-associated secretory cytokines. Gypenoside L also can activate p38 and ERK MAPK pathways and NF-κB pathway to induce senescence. Gypenoside L exhibits anti-tumor and anti-inflammatory activities[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 94987-09-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N8211. | |
| Gypenoside XLIX | Gypenoside XLIX. Group: Biochemicals. Grades: Plant Grade. CAS No. 94987-08-3. Pack Sizes: 20mg. Molecular Formula: C52H86O21, Molecular Weight: 1047.23. US Biological Life Sciences. | Worldwide |
| Gypenoside XLIX | Gypenoside XLIX is a multifunctional bioactive compound that can be isolated from Gynostemma pentaphyllum, with a Ka value of 1.58 μM for its binding to SIRT1. Gypenoside XLIX acts as a PPAR-α agonist. It inhibits the activation of TLR4-mediated NF-κB signaling pathway by activating the Sirt1/Nrf2 signaling pathway, reduces ROS accumulation, and alleviates hepatic inflammatory injury in mice with sepsis-induced liver disease. Gypenoside XLIX targets SIRT1 to block YAP-NLRP3 activation and improve sepsis-induced cardiomyopathy. Gypenoside XLIX inhibits apoptosis (Apoptosis), pyroptosis (Pyroptosis), autophagy (Autophagy), lipid peroxidation, pro-inflammatory cytokines and anti-inflammatory cytokines. Gypenoside XLIX alleviates sepsis-induced splenic injury by inhibiting inflammation and oxidative stress, and mitigates sepsis-associated encephalopathy by targeting PPAR-α. Gypenoside XLIX prevents acute kidney injury by inhibiting IGFBP7/IGF1R-mediated programmed cell death and inflammation. Gypenoside XLIX inhibits the expression and activity of vascular cell adhesion molecule-1 in cytokine-induced human endothelial cells. Gypenoside XLIX is applicable to research related to acute liver injury, lung injury, cardiomyopathy, acute splenic injury, sepsis-associated encephalopathy, acute kidney injury, atherosclerosis and chronic inflammation[1][2][3][4][5][6][7]. Uses: Scientific research. Category: SignalÂ… | |
| Gypenoside XLVI | Gypenoside XLVI. Group: Biochemicals. Grades: Plant Grade. CAS No. 94705-70-1. Pack Sizes: 10mg. Molecular Formula: C48H82O19, Molecular Weight: 963.16. US Biological Life Sciences. | Worldwide |
| Gypenoside XVII | Gypenoside XVII. Group: Biochemicals. Alternative Names: Gynosaponin S. Grades: Plant Grade. CAS No. 80321-69-3. Pack Sizes: 20mg. Molecular Formula: C48H82O18, Molecular Weight: 947.154. US Biological Life Sciences. | Worldwide |
| Gypsetin | It is produced by the strain of Nannizzia gypsea var. incurvata IFO 9228. It can inhibit acylcoenzyme A, cholesterol acyltransferase (ACAT) activity, inhibit rat liver microbody ACAT with IC50 of 18 μmol/L, and its action is competitive with oleoyl-COA substrate, Ki value is 5.5 μmol/L. It also inhibits [14C] oleic acid from forming cholesterol esters with IC50 of 0.65 μmol/L. Synonyms: Gypsetine; (-)-Gypsetin; 8a,16a-Dihydroxy-5a,13a-bis(1,1-dimethylallyl)-(1)-benzazolidine-(3''',2''':4'',5'')azolidino-(1'',2'':4',5')(1,4)perhydrodiazin-(1',2':1,5)azolidino-(2,3-b)-(1)-benzazolidine-7,15-dione; Pyrazino(1'',2'':1,5; 4'',5'':1',5')dipyrrolo(2,3-b:2',3'-b')diindole-7,15(5H,7aH)-dione,5a,13a-bis(1,1-dimethyl-2-propenyl)-5a,8,8a,13,13a,15a,16,16a-octahydro-8a,16a-dihydroxy-, (5aalpha,7aalpha,8abeta,13abeta,15aalpha,16aalpha)-. CAS No. 155114-38-8. Molecular formula: C32H36N4O4. Mole weight: 540.66. | |
| Gypsogenic acid | Gypsogenic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 5143-5-5. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| Gypsogenin 3-O- β-D-glucuronopyranoside | Gypsogenin 3-O- β-D-glucuronopyranoside. Group: Biochemicals. Grades: Plant Grade. CAS No. 96553-02-5. Pack Sizes: 10mg. Molecular Formula: C36H54O10, Molecular Weight: 646.82. US Biological Life Sciences. | Worldwide |
| Gypsum Submicron | Gypsum Submicron. Molecular formula: CaSO4 2H2O. Purity: 99.9%. | |
| Gyrane | Gyrane. CAS No. 24237-00-1. VIGON Item # 503223. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| Gyrophoric acid | Gyrophoric acid isolated from the herbs of Parmelia tinctorum Despr. Uses: Anti-tumor; anti-cancer; antibacterial; antimicrobial; anti-proliferative/cytotoxic effect. Synonyms: triorsellinic acid; 4-[4-(2,4-dihydroxy-6-methylbenzoyl)oxy-2-hydroxy-6-methylbenzoyl]oxy-2-hydroxy-6-methylbenzoic acid. Grade: 0.98. CAS No. 548-89-0. Molecular formula: C24H20O10. Mole weight: 468.4. | |
| GYY4137 | GY4137 is a sustained-release H2S donor possessing vasodilatory, antihypertensive, and anti-inflammatory activities. GY4137 can inhibit cell growth, induce apoptosis, and cause cell cycle arrest by blocking the STAT3 pathway, demonstrating potent anticancer activity[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 106740-09-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107632. | |
| GYY 4137 | Water-soluble, slow-releasing hydrogen sulfide (H2S) donor. Exhibits vasodilator and antihypertensive activity. Anti-inflammatory. Inhibits LPS-induced release of proinflammatory mediators (IL-1beta, IL-6, TNF-alpha, nitric oxide (NO) and PGE2) and increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-kappaB, ATF-2 and HSP27 dependent pathways. Causes stomatal opening and reduces nitric oxide accumulation in plants. Oxidative stress-induced cell death inhibitor. Shows novel anti-cancer effects in vitro and in vivo. Anti-thrombotic via p-selectin dependent mechanism. Group: Biochemicals. Grades: Highly Purified. CAS No. 106740-09-4. Pack Sizes: 10mg, 50mg. Molecular Formula: C11H16NO2PS2 C4H9NO. US Biological Life Sciences. | Worldwide |
| GYY 4137 morpholine salt | GYY 4137 morpholine salt. Group: Biochemicals. Grades: Purified. CAS No. 106740-09-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GYY-4137 Morpholine salt | GYY-4137 Morpholine salt is a novel water-soluble and slow releasing Hydrogen sulfide(H2S) donor. It protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis in rats. It inhibits the inflammatory response by suppressing the activation of nuclear factor-kappa B and mitogen-activated protein kinases in Coxsackie virus B3-infected rat cardiomyocytes. It exhibits potent anti-cancer activity. It exhibits vasodilator and antihypertensive activity in rats, in either the acute or chronic hypertension models. It does not influence vascular smooth muscle cell viability in culture. It also protects against endotoxic shock in rats, inhibiting tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 production and reducing NF-κB activation, iNOS and cyclooxygenase-2 expression, and NO and prostaglandin E2 generation. Uses: Gyy-4137 morpholine salt inhibits the inflammatory response. it exhibits potent anti-cancer activity. it exhibits vasodilator and antihypertensive activity. Synonyms: GYY4137; GYY-4137; GYY 4137; GYY 4137 morpholine salt; ZYJ1122; ZYJ 1122; ZYJ-1122. GYY4137 Morpholine salt; (4-Methoxyphenyl)morpholino-phosphinodithioic acid compound with morpholine; ZYJ1122 morpholine salt; ZYJ-1122 morpholine salt. Grade: ≥95%. CAS No. 106740-09-4. Molecular formula: C15H25N2O3PS2. Mole weight: 376.47. | |
| GZD824 | GZD824 potently suppressed proliferation of Bcr-Abl-positive K562 and Ku812 human CML cells with IC(50) values of 0.2 and 0.13 nM, respectively. It also displayed good oral bioavailability (48.7%), a reasonable half-life (10.6 h), and promising in vivo antitumor efficacy. GZD824 induced tumor regression in mouse xenograft tumor models driven by Bcr-Abl(WT) or the mutants and significantly improved the survival of mice bearing an allograft leukemia model with Ba/F3 cells harboring Bcr-Abl(T315I). Synonyms: GZD824; GZD 824; GZD-824. Grade: >98%. CAS No. 1257628-77-5. Molecular formula: C29H27F3N6O. Mole weight: 532.56. | |
| GZD824 Dimesylate | GZD824 Dimesylate is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC50 of 0.34 nM and 0.68 nM, respectively. Synonyms: Olverembatinib dimesylate; HQP1351 dimesylate; GZD 824 Dimesylate; GZD-824 Dimesylate; 3-((1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide dimethanesulfonate; Benzamide, 4-methyl-N-(4-((4-methyl-1-piperazinyl)methyl)-3-(trifluoromethyl)phenyl)-3-(2-(1H-pyrazolo(3,4-b)pyridin-5-yl)ethynyl)-, methanesulfonate (1:2). Grade: ≥99%. CAS No. 1421783-64-3. Molecular formula: C29H27F3N6O.2CH4O3S. Mole weight: 724.77. | |
| GZD856 | GZD856 is a potent and orally active inhibitor of PDGFRα/β with IC50s of 68.6 and 136.6 nM, respectively. It is also a Bcr-AblT315I inhibitor with IC50s of 19.9 and 15.4?nM for native Bcr-Abl and the T315I mutant. GZD856 has antitumor activity. Synonyms: GZD-856; 4-Methyl-N-{4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl}-3-(pyrazolo[1,5-a]pyrimidin-6-ylethynyl)benzamide; Benzamide, 4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-(2-pyrazolo[1,5-a]pyrimidin-6-ylethynyl)-. Grade: ≥98%. CAS No. 1257628-64-0. Molecular formula: C29H27F3N6O. Mole weight: 532.56. | |
| GZD856 formic | GZD856 formic is a potent and orally active inhibitor of PDGFRα/β with IC50s of 68.6 and 136.6 nM, respectively. It is also a Bcr-AblT315I inhibitor with IC50s of 19.9 and 15.4?nM for native Bcr-Abl and the T315I mutant. GZD856 formic has antitumor activity. Synonyms: Benzamide, 4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-(2-pyrazolo[1,5-a]pyrimidin-6-ylethynyl)-, formic acid. Grade: ≥98%. Molecular formula: C30H29F3N6O3. Mole weight: 578.58. | |
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