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| Product | Description | |
|---|---|---|
| Lucidin | Botanical Source: Group: Biochemicals. Alternative Names: 1,3-Dihydroxy-2-hydroxymethyl-9,10-anthracenedione, 9CI. Grades: Plant Grade. CAS No. 478-08-0. Pack Sizes: 10mg. Molecular Formula: C15H10O5, Molecular Weight: 270.24. US Biological Life Sciences. |  Worldwide |
| Lucidin | Lucidin is a natural component of Rubia tinctorum L. It exhibits antibacterial activity. Alternative Names: Henine; NSC 30546; NSC30546; NSC-30546. Grades: >98%. CAS No. 478-08-0. Molecular formula: C15H10O5. Mole weight: 270.24. |  |
| Lucidone | Lucidone, coming from the root of Lindera strychnifolia, may possess antioxidant and anti-inflammatory properties and may be useful for the prevention of free radical-induced skin damage. The anti-inflammatory activity of lucidone might cause by the inhibition of iNOS and COX-2 expressions through the down-regulation of NF-κB and AP-1 binding activity. Besides, the effects of lucidone on tyrosinase and antimelanogenic activity were investigated, lucidone strongly inhibits the activity of mushroom tyrosinase. The antimelanogenic activity of lucidone is probably due to its inhibition of tyrosinase activity and the suppression of tyrosinase and MITF expression. Uses: Antimelanogenic / antioxidant / anti-inflammatory. Alternative Names: Lucidone;19956-53-7;3-hydroxy-4-methoxy-2-[(E)-3-phenylprop-2-enoyl]cyclopenta-2,4-dien-1-one;4-Cyclopentene-1,3-dione, 2-(1-hydroxy-3-phenyl-2-propenylidene)-4-methoxy-, (Z,E)-;SCHEMBL6846053;CHEBI:183569;LMPK12120439;AKOS032948482;AKOS040744744;FS-9524;4-Cyclopentene-1,3-dione, 2-[(2E)-1-hydroxy-3-phenyl-2-propenylidene]-4-methoxy-, (2Z)-;DA-65101;(2Z)-2-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-4-methoxycyclopent-4-ene-1,3-dione;4-Cyclopentene-1,3-dione, 2-(-hydroxycinnamylidene)-4-methoxy- (8CI); (2Z)-2-[(2E)-1-Hydroxy-3-phenyl-2-propenylidene]-4-methoxy-4-cyclopentene-1,3-dione. Grades: >98%. CAS No. 19956-53-7. Molecular formula: C30H46O5. Mole weight: 486.7. | |
| Lucifensin | Lucifensin is the key antimicrobial peptide of the green bottle fly larvae Lucilia sericata. This defensin protects the larvae when they are exposed to the infectious environment of a wound during maggot therapy and it also contributes as a disinfectant and healing factor. | |
| Luciferase | Luciferase is an analytical enzyme used as a component of lysis solution to measure luminescence signals. It has been used to investigate the sensitivity of dark mutants of various luminescent bacterial strains to reactive oxygen species. Alternative Names: EC 1.14.14.3; Bacterial Luciferase; Luciferase from Photobacterium fischeri. Grades: >95%. CAS No. 9014-00-0. Molecular formula: H14. Mole weight: 14.11. | |
| Luciferase (bacterial) | Luciferase (bacterial) catalyzes the oxidation of a long-chain aldehyde and reduced flavin mononucleotide. Luciferase (bacterial) protection against oxidative stress for bacterial luminescence[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9014-00-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1004. |  |
| Luciferase, firefly | Luciferase, firefly is a bioluminescent enzyme responsible for bioluminescence in fireflies and click beetles. Alternative Names: Luciferase from Photinus pyralis (firefly). Grades: >98%. CAS No. 61970-00-1. Molecular formula: C18H19N5O. Mole weight: 321.4. | |
| Luciferase, firefly | Luciferase, firefly is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles. Luciferase, firefly catalytic substrate is D-luciferin (HY-12591B)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 61970-00-1. Pack Sizes: 1 mg. Product ID: HY-P1004A. | |
| Luciferase from E. coli, Recombinant | Luciferase is an enzyme that catalyzes production of light from luciferin in the presence of Mg2+-ATP and oxygen. The reaction of this enzyme with luciferin, ATP, and O2 results in the emission of light. Luciferase activity can be inhibited by general anesthetics including isoflurane and ketamine/medetomidine thereby affecting the sensitivity of bioluminescence imaging. Group: Enzymes. Synonyms: Photinus-luciferin 4-monooxygenase (ATP-hydrolysing); firefly luciferase; luciferase (firefly luciferin); Photinus luciferin 4-monooxygenase (adenosine triphosphate-hydrolyzing); firefly luciferin luciferase; Photinus pyralis luciferase; EC 1.13.12.7; 61970-00-1. Enzyme Commission Number: EC 1.13.12.7. Luciferase. Mole weight: ca. 60 kDa. Activity: > 1.0 x 10^9 relative light units (RLU)/mg lyophilizate Specific activity: 1.4 x 10^11 RLU/mg purified protein. Stability: stable at 25°C for at least 5 days (liquid form). Appearance: White lyophilizate. Storage: at -20°C. Source: E. coli. Species: E. coli. Photinus-luciferin 4-monooxygenase (ATP-hydrolysing); firefly luciferase; luciferase (firefly luciferin); Photinus luciferin 4-monooxygenase (adenosine triphosphate-hydrolyzing); firefly luciferin luciferase; Photinus pyralis luciferase; EC 1.13.12.7; 61970-00-1. Cat No: NATE-1253. |  |
| Luciferase from Photinus pyralis (firefly) | Luciferase from Photinus pyralis (firefly). Uses: For analytical and research use. CAS No. 61970-00-1. Catalog: AP61970001. |  |
| Luciferase from Photinus pyralis (firefly), Recombinant | Firefly luciferase is an enzyme that catalyzes production of light from luciferin in the presence of Mg2+-ATP and oxygen. The reaction of this enzyme with luciferin, ATP, and O2 results in the emission of light. Luciferase activity can be inhibited by general anesthetics including isoflurane and ketamine/medetomidine thereby affecting the sensitivity of bioluminescence imaging. Applications: The reaction of this enzyme with luciferin, atp, and o2 results in the emission of light. luciferase can be used to detect trace amounts of atp. firefly luciferase is also one of the most commonly utilized reporter genes for the study of gene expression. the bioluminescent rea.pe I , > 5 ,000 ,000 units/mg protein; Type II, 15-30×106 light units/mg protein. Storage: -70°C. Form: Type I, Supplied as a solution in 50 mM Tris HCl pH 8.0, 1 mM dithiothreitol, 1 mM EDTA, and 10% (v/v) glycerol; Type II, Lyophilized powder approximately 20% protein; balance is primarily NaCl, HEPES buffer salts, and carbohydrate. Source: E. coli. Species: Photinus pyralis (firefly). Photinus-luciferin 4-monooxygenase (ATP-hydrolysing); firefly luciferase; luciferase (firefly luciferin); Photinus luciferin 4-monooxygenase (adenosine triphosphate-hydrolyzing); firefly luciferin luciferase; Photinus pyralis luciferase; EC 1.13.12.7; 61970-00-1. Cat No: NATE-0424. | |
| Luciferase from Vibrio fischeri (Photobacterium f) | Luciferase from Vibrio fischeri (Photobacterium f). Uses: For analytical and research use. CAS No. 9014-00-0. EC Number: 232-751-7. Catalog: AP9014000. | |
| Luciferase-IN-1 | Luciferase-IN-1 is a luciferase inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10205-56-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136706. | |
| Luciferase-IN-3 | Luciferase-IN-3 (compound 5h) is an inhibitor of ATP-dependent luciferase (Firefly luciferase), the major light-emitting enzyme in fireflies and kowtow bugs. Firefly luciferase-IN-2 inhibits P. pyralis luciferase with an IC50 of 3.2 μM, while the inhibitory potency against R. reniformis is not significant[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 690987-97-4. Pack Sizes: 1 mg. Product ID: HY-158256. | |
| Lucifer Yellow CH dipotassium salt | Lucifer Yellow CH dipotassium is a high-intensity fluorescent probe containing free hydrazyl groups. Lucifer Yellow CH can react with fatty aldehydes at room temperature. Lucifer Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Lucifer yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 71206-95-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W127715. | |
| Lucifer yellow iodoacetamide dipotassium salt | Lucifer yellow iodoacetamide dipotassium salt is a thiol-reactive fluorescent polar tracer. CAS No. 176182-05-1. Molecular formula: C16H12IK2N3O9S2. Mole weight: 659.51. | |
| Lucifer yellow vs dilithium salt | Lucifer yellow vs dilithium salt. Alternative Names: 4-AMINO-N-[3-(VINYLSULFONYL)-PHENYL]NAPHTHALIMIDE-3,6-DISULFONATE DILITHIUM SALT;LUCIFER YELLOW VS;LUCIFER YELLOW VS DILITHIUM SALT;DILITHIUM 4-AMINO-N-[3-(VINYLSULFONYL)PHENYL]NAPHTHALIMIDE-3,6-DISULFONATE;LUCIFER YELLOW VS DILITHIUM SALT, FOR FL UORESCE. CAS No. 71231-14-6. Molecular formula: C20H12Li2N2O10S3. Mole weight: 550.5g/mol. IUPAC Name: dilithium;6-amino-2-(3-ethenylsulfonylphenyl)-1,3-dioxobenzo[de]isoquinoline-5,8-disulfonate. SMILES: [Li+].[Li+].C=CS(=O)(=O)C1=CC=CC(=C1)N2C(=O)C3=CC(=CC4=C3C(=CC(=C4N)S(=O)(=O)[O-])C2=O)S(=O)(=O)[O-]. InChI: InChI=1S/C20H14N2O10S3.2Li/c1-2-33(25,26)11-5-3-4-10(6-11)22-19(23)14-8-12(34(27,28)29)7-13-17(14)15(20(22)24)9-16(18(13)21)35(30,31)32;;/h2-9H,1,21H2,(H,27,28,29)(H,30,31,32);;/q;2*+1/p-2. |  |
| Lucigenin | Lucigenin is a chemiluminescence probe. Lucigenin can be used to detect the production of endogenous superoxide anion radical (O2-). Lucigenin is extremely sensitive to chloride ions, while it combined with chloride ions, the fluorescence will be quenched. Lucigenin also can be used as a chloride indicator. Ex/Em=455/505 nm[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC-151912; L-6868. CAS No. 2315-97-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-D0720. | |
| Lucigenin | Lucigenin is a fluoerscent probe that exhibits a bluish-green fluorescence in the presence of superoxide and chloride. It can be used to detect superoxide production by enzymatic and cellular sources. Alternative Names: 10,10'-dimethyl-9,9'-biacridinium, dinitrate; N,N'-Dimethyl-9,9'-biacridinium dinitrate; Lucigenin Nitrate; NSC 151912; Bis(N-methylacridinium) Nitrate; 9,9'-Bis(N-methylacridinium nitrate). Grades: ≥95%. CAS No. 2315-97-1. Molecular formula: C28H22N2.2NO3. Mole weight: 510.50. | |
| Lucilactaene | It is produced by the strain of Fusarium sp. RK-97-94. It is a P53-transfected tumor cell cycle inhibitor. It inhibits the cell cycle progression of H1299/TSP53 in G1 phase. Molecular formula: C22H27NO6. Mole weight: 401.45. | |
| Lucilin, partial | Lucilin, partial was found in Lucilia sericata [Green bottle fly] and has antimicrobial activity. Grades: >96% by HPLC. | |
| Lucinactant | Lucinactant (trade name Surfaxin) is a liquid medication used to treat Infant Respiratory Distress Syndrome in infants. A synthetic human lung surfactant consisting of peptide KL4, dipalmitoylphosphatidylcholine, palmitoyloleoylphosphatidylglycerol, and palmitic acid. Alternative Names: ATI 02; KL-surfactant; KL4-surfactant; Surfaxin. Grades: 98%. CAS No. 825600-90-6. Molecular formula: C128H242N26O24. Mole weight: 2529.5. | |
| Lucitanib | Lucitanib (E-3810) is a novel dual inhibitor of VEGFR and FGFR, potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 with IC50s of 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E-3810. CAS No. 1058137-23-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15391. | |
| Luc Yellow CH dilithium | Luc Yellow CH dilithium is a high-intensity fluorescent probe containing free hydrazyl groups. Luc Yellow CH can react with fatty aldehydes at room temperature. Luc Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Luc Yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 67769-47-5. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128692. | |
| Lucyoside B | Lucyoside B. Group: Biochemicals. CAS No. 91174-19-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Lucyoside B | Lucyoside B is a triterpenoid compound found in the herbs of Luffa cylindrica ROEM. Alternative Names: Arjunolitin; Asterbatanoside C; (2alpha,3beta,4alpha)-3-(beta-D-Glucopyranosyloxy)-2,23-dihydroxy-olean-12-en-28-oic acid beta-D-glucopyranosyl ester. Grades: >98%. CAS No. 91174-19-5. Molecular formula: C42H68O15. Mole weight: 812.99. | |
| LUF 5834 | LUF 5834. Group: Biochemicals. Grades: Purified. CAS No. 333962-91-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| LUF6000 | LUF6000 is an orally active allosteric modulator of the A3 adenosine receptor. LUF6000 has potent anti-inflammatory effect[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 890087-21-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13236. | |
| LUF 6283 | LUF 6283. Group: Biochemicals. Grades: Purified. CAS No. 92933-48-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| LUF7244 | LUF7244 is a selective allosteric modulator of Kv11.1 channels. LUF7244 inhibits early afterdepolarizations. LUF7244 can be used for anti-arrhythmia research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1821638-43-0. Pack Sizes: 5 mg. Product ID: HY-137986. | |
| Lufenuron | Lufenuron is an orally active lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods. Lufenuron induces reproductive toxicity, genotoxic effects and oxidative stresses in pregnant albino rats and their fetuses[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 103055-07-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-115584. | |
| Lufenuron | Lufenuron is a benzoylurea pesticide which inhibits the production of chitin in larval fleas. Alternative Names: N-[[[2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino]carbonyl]-2,6-difluorobenzamide; (RS)-1-[2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea; CGA 184699; Cigna; Fluphenacur; Fuoro; Match; Match (pesticide); Match 5EC; Program. Grades: >95%. CAS No. 103055-07-8. Molecular formula: C17H8Cl2F8N2O3. Mole weight: 511.15. | |
| Lufenuron | Lufenuron. Group: Biochemicals. Alternative Names: N-[[[2, 5-Dichloro-4- (1, 1, 2, 3, 3, 3-hexafluoropropoxy) phenyl]amino]carbonyl]-2, 6-difluorobenzamide; (RS) -1-[2, 5-Dichloro-4- (1, 1, 2, 3, 3, 3-hexafluoropropoxy) phenyl]-3- (2, 6-difluorobenzoyl) urea; CGA 184699; Cigna; Fluphenacur; Fuoro; Lufenuron; Match; Match (pesticide); Match 5EC; Program. Grades: Highly Purified. CAS No. 103055-07-8. Pack Sizes: 250mg. Molecular Formula: C17H8Cl2F8N2O3, Molecular Weight: 511.15. US Biological Life Sciences. | Worldwide |
| Lufenuron-[13C6] | Lufenuron-[13C6] is the labelled analogue of Lufenuron, a benzoylurea pesticide which inhibits the production of chitin in larval fleas. Alternative Names: Lufenuron-13C6; N-[[2,5ropoxy)phenifluorobenzamide-13C6. Grades: 98% by CP. Molecular formula: C11[13C]6H8Cl2F8N2O3. Mole weight: 517.09. | |
| Lufotrelvir | Lufotrelvir (PF-07304814), a phosphate proagent of PF-00835231, acts as a potent 3CLpro protease (Mpro) inhibitor with SARS-CoV-2 antiviral activity. Lufotrelvir binds and inhibits SARS-CoV-2 3CLpro activity with a Ki of 174nM. Lufotrelvir is promising single antiviral agent and also can be used for the research of combination with other antivirals that target other critical stages of the coronavirus life cycle. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-07304814. CAS No. 2468015-78-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-138078. | |
| Luisol A | Luisol A, an aromatic tetraol, is a major metabolite of an estuarine marine actinomycete of the genus Streptomyces. Luisol A, is an anthraquinone antibiotic analog[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 225110-59-8. Pack Sizes: 1 mg. Product ID: HY-126708. | |
| Luliconazole | Luliconazole is a topical antifungal agent that acts by unknown mechanisms but is postulated to involve altering the synthesis of fungi cell membranes. Category: Other apis. Synonyms: Lulicon. Luzu. NND-502. CAS No. 187164-19-8. Product ID: API187164198. Molecular formula: C14H9Cl2N3S2. Mole weight: 354.3. EINECS: 878-713-9. SMILES: C1C(SC(=C(C#N)N2C=CN=C2)S1)C3=C(C=C(C=C3)Cl)Cl. Appearance: White Solid. Standard: In-house. |  |
| Luliconazole | Luliconazole. Uses: For analytical and research use. CAS No. 187164-19-8. Mole weight: 354.28. Catalog: AP187164198. | |
| Luliconazole | Luliconazole is an azole antifungal drug. Its mechanism of action involves inhibition of ergosterol biosynthesis by inhibition of sterol 14α-demethylase. Group: Biochemicals. Alternative Names: [R-(E)]-α-[4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-1-acetonitrile; Lulicon; NND 502. Grades: Highly Purified. CAS No. 187164-19-8. Pack Sizes: 500mg, 1g. Molecular Formula: C??H?Cl?N?S?, Molecular Weight: 354.28. US Biological Life Sciences. | Worldwide |
| Luliconazole Impurity 1 | Luliconazole Impurity 1. Uses: For analytical and research use. CAS No. 101530-21-6. Molecular formula: C14H9Cl2N3S2. Mole weight: 354.27. Catalog: APB101530216. | |
| Luliconazole Impurity 2 | Luliconazole Impurity 2. Uses: For analytical and research use. CAS No. 1579886-24-0. Molecular formula: C14H11Cl2N3OS2. Mole weight: 372.28. Catalog: APB1579886240. | |
| Luliconazole Impurity 3 | Luliconazole Impurity 3. Uses: For analytical and research use. CAS No. 256424-63-2. Molecular formula: C14H9Cl2N3S2. Mole weight: 354.27. Catalog: APB256424632. | |
| Luliconazole Impurity 4 | Luliconazole Impurity 4. Uses: For analytical and research use. CAS No. 101529-76-4. Molecular formula: C14H9Cl2N3S2. Mole weight: 354.27. Catalog: APB101529764. | |
| Lulizumab | Lulizumab (Humanized Anti-CD28 Recombinant Antibody) is an anti-CD28 domain antibody antagonist. Lulizumab inhibits T-cell activation by selectively targeting the CD28 signal. In a sensitized non-human primate kidney transplantation model, when combined with Carfilzomib (HY-10455), Lulizumab can regulate immune cells and prolong the survival time of the graft[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-931699 Antibody. CAS No. 2235419-62-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99302. | |
| Lumacaftor | Lumacaftor is the second investigational oral candidate compound for the treatment of cystic fibrosis (CF). Lumacaftor may act to restore the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, the defective cell membrane protein responsible for the progression of CF. Lumacaftor defects in the CFTR protein affect the transport of chloride and other ions across cells, and lead to the accumulation of thick, sticky mucus in the lungs of patients with CF. This mucus fosters chronic infection and inflammation, and results in irreversible lung damage. Alternative Names: VX-809; VX809; VX 809; VRT 826809; VRT826809; VRT-826809. Grades: ≥98%. CAS No. 936727-05-8. Molecular formula: C24H18F2N2O5. Mole weight: 452.41. | |
| Lumacaftor | Lumacaftor (VX-809; VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-809; VRT 826809. CAS No. 936727-05-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13262. | |
| Lumacaftor | Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM). Category: Active pharmaceutical ingredients. CAS No. 936727-05-8. Product ID: API936727058. Molecular formula: C24H18F2N2O5. Mole weight: 452.41. | |
| Lumacaftor-d4 | Lumacaftor-d4 is the deuterium labeled Lumacaftor (HY-13262)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-809-d4; VRT 826809-d4. CAS No. 2733561-44-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-13262S. | |
| Lumasiran | Lumasiran is a siRNA product that reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1). Alternative Names: ALN-G01; RNA, (Gm-sp-Am-sp-Cm-Um-Um-Um-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-Um-Gm-Gm-Am-Am-Am-Um-Am-Um-Am), 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)A-sp-Um-Am-Um-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-Am-Gm-Gm-Am-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)A-Am-Am-Gm-Um-Cm-sp-Cm-sp-Am) (1:1). Grades: 98% by SEC-HPLC. CAS No. 1834610-13-7. Molecular formula: C530H712F10N173O320P43S6. Mole weight: 16,340 Da. | |
| Lumasiran | Lumasiran (ALN-G01), a siRNA product, reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALN-G01. CAS No. 1834610-13-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132588. | |
| Lumasiran sodium | Lumasiran sodium is a siRNA product that reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1). Alternative Names: ALN-G01 sodium; Oxlumo; RNA, (Gm-sp-Am-sp-Cm-Um-Um-Um-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-Um-Gm-Gm-Am-Am-Am-Um-Am-Um-Am), 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate] sodium salt, complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)A-sp-Um-Am-Um-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-Am-Gm-Gm-Am-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)A-Am-Am-Gm-Um-Cm-sp-Cm-sp-Am) sodium salt (1:21:1:22). CAS No. 1834612-06-4. Molecular formula: C530H669F10N173O320P43S6Na43. Mole weight: 17,286 Da. | |
| Lumasiran sodium | Lumasiran sodium, an investigational RNA interference (RNAi) therapeutic agent, reduces hepatic oxalate production by targeting glycolate oxidase. Lumasiran sodium reduces urinary oxalate excretion, the cause of progressive kidney failure in primary hyperoxaluria type 1 (PH1) [1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1834612-06-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132613. | |
| Lumateperone | Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM). Category: Active pharmaceutical ingredients. CAS No. 313368-91-1. Product ID: API313368911. Molecular formula: C24H28FN3O. Mole weight: 393.5. | |
| Lumateperone | Lumateperone (ITI-007) is an orally active 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone has anticancer activity and can also be used for the study of schizophrenia and bipolar depression[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ITI-007. CAS No. 313368-91-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17637. | |
| Lumateperone-[d4] | Lumateperone-[d4] is a labelled form of Lumateperone, which is a highly potent 5HT2A antagonist for the treatment of sleep maintenance insomnia. Alternative Names: 1-(4-Fluorophenyl-2,3,5,6-d4)-4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)butan-1-one; Lumateperone D4; 1-(4-Fluorophenyl-2,3,5,6-d4)-4-[(6bR,10aS)-2,3,6b,9,10,10a-hexahydro-3-methyl-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl]-1-butanone; ITI 007-d4; Lumateperone Deuterated. Grades: >95%. CAS No. 2135466-52-1. Molecular formula: C24H24D4FN3O. Mole weight: 397.52. | |
| Lumateperone Impurity 10 | Lumateperone Impurity 10. Uses: For analytical and research use. CAS No. 1576240-15-7. Molecular formula: C24H28FN3O. Mole weight: 393.5. Catalog: APB1576240157. | |
| Lumateperone Impurity 11 | Lumateperone Impurity 11. Uses: For analytical and research use. CAS No. 1469343-42-7. Molecular formula: C24H30FN3O. Mole weight: 395.52. Catalog: APB1469343427. | |
| Lumateperone Impurity 12 | Lumateperone Impurity 12. Uses: For analytical and research use. CAS No. 313368-82-0. Molecular formula: C23H26FN3O. Mole weight: 379.48. Catalog: APB313368820. | |
| Lumateperone Impurity 13 | Lumateperone Impurity 13. Uses: For analytical and research use. Molecular formula: C24H28FN3O2. Mole weight: 409.51. Catalog: APB11535. | |
| Lumateperone Impurity 14 | Lumateperone Impurity 14. Uses: For analytical and research use. CAS No. 1576239-82-1. Molecular formula: C24H29N3O. Mole weight: 375.52. Catalog: APB1576239821. | |
| Lumateperone Impurity 16 | Lumateperone Impurity 16. Uses: For analytical and research use. CAS No. 313544-31-9. Molecular formula: C16H17N3O3. Mole weight: 299.33. Catalog: APB313544319. | |
| Lumateperone Impurity 17 | Lumateperone Impurity 17. Uses: For analytical and research use. CAS No. 313544-32-0. Molecular formula: C16H19N3O3. Mole weight: 301.35. Catalog: APB313544320. | |
| Lumateperone Impurity 18 | Lumateperone Impurity 18. Uses: For analytical and research use. CAS No. 313544-76-2. Molecular formula: C17H21N3O3. Mole weight: 315.37. Catalog: APB313544762. | |
| Lumateperone Impurity 19 | Lumateperone Impurity 19. Uses: For analytical and research use. CAS No. 1059630-08-8. Molecular formula: C14H17BrN2O2. Mole weight: 325.21. Catalog: APB1059630088. | |
| Lumateperone Impurity 20 | Lumateperone Impurity 20. Uses: For analytical and research use. CAS No. 313369-16-3. Molecular formula: C16H19N3O3. Mole weight: 301.35. Catalog: APB313369163. | |
| Lumateperone Impurity 21 | Lumateperone Impurity 21. Uses: For analytical and research use. CAS No. 313369-17-4. Molecular formula: C16H21N3O2. Mole weight: 287.36. Catalog: APB313369174. | |
| Lumateperone Impurity 22 | Lumateperone Impurity 22. Uses: For analytical and research use. CAS No. 313368-81-9. Molecular formula: C13H17N3. Mole weight: 215.3. Catalog: APB313368819. | |
| Lumateperone Impurity 23 | Lumateperone Impurity 23. Uses: For analytical and research use. CAS No. 2402752-92-3. Molecular formula: C14H20ClN3. Mole weight: 265.79. Catalog: APB2402752923. | |
| Lumateperone Impurity 24 | Lumateperone Impurity 24. Uses: For analytical and research use. CAS No. 2649799-31-3. Molecular formula: C38H52N6O. Mole weight: 608.88. Catalog: APB2649799313. | |
| Lumateperone Impurity 25 | Lumateperone Impurity 25. Uses: For analytical and research use. CAS No. 2339904-91-3. Molecular formula: C14H19N3. Mole weight: 229.33. Catalog: APB2339904913. | |
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