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| Product | Description | |
|---|---|---|
| L-3-Carbamoylphenylalanine | L-3-Carbamoyl phenyl alanine. Group: Biochemicals. Alternative Names: (2S) -2-Amino-3- (3-carbamoylphenyl) propanoic acid. Grades: Highly Purified. CAS No. 1217651-22-3. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences. |  Worldwide |
| L-3-Carbamoylphenylalanine 99+% | L-3-Carbamoylphenylalanine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| L-3-cyanoalanine synthase | Contains pyridoxal phospate. Group: Enzymes. Synonyms: β-cyanoalanine synthase; β-cyanoalanine synthetase; β-cyano-L-alanine synthase; L-cysteine hydrogen-sulfide-lyase (adding HCN). Enzyme Commission Number: EC 4.4.1.9. CAS No. 9059-53-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5342; L-3-cyanoalanine synthase; EC 4.4.1.9; 9059-53-4; β-cyanoalanine synthase; β-cyanoalanine synthetase; β-cyano-L-alanine synthase; L-cysteine hydrogen-sulfide-lyase (adding HCN). Cat No: EXWM-5342. |  |
| L3MBTL3 MBT Domain Blocker, UNC1215 (Lethal(3)malignant Brain Tumor-like Protein 3 MBT Domain Blocker, 2-Phenylamino-1, 4-bis (4- (pyrrolidinyl) piperidinyl) benzamide, TFA, 2-(Phenylamino)-1,4-phenylene-bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone, TFA) | A cell-permeable pyrrolidinyl-piperidinyl-benzamide that effectively competes against H4K20Me2 peptide for L3MBTL3 binding by targeting the first two L3MBTL3 MBT domains (Kd = 120nM in binding studies using recombinant 3MBT fragment), while exhibiting much reduced potency against L3MBTL1-H4K20Me1, 53BP1-H4K20Me2, MBTD1-H4K20Me1, or L3MBTL4-H2AK36Me1 interaction (IC50 ≥2uM; [peptide] = 150nM). Shown to increase GFP-L3MBTL fusion nucleus mobility (10nM to 1uM) in HEK293 transfectants. X-ray structural analysis reveals two 3MBT are bridged together by two UNC1215 molecules in a reciprocal fashion. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| L-3-Methoxyphenylalanine | L-3-Methoxyphenylalanine. Synonyms: L-Phe(3-OMe)-OH; m-Methoxy-L-phenylalanine; (S)-2-Amino-3-(3-methoxyphenyl)propionic acid. Grade: 99%. CAS No. 33879-32-2. Molecular formula: C10H13NO3. Mole weight: 195.2. |  |
| L-3-O-Methyl DOPA-[d3] | L-3-O-Methyl DOPA-[d3] is the labelled analogue of L-3-O-Methyl DOPA, which is a metabolite of L-DOPA. Synonyms: 3-O-Methyldopa d3; L-3-(4-Hydroxy-3-methoxy-d3-phenyl)alanine; L-3-O-Methyl-DOPA-d3; 3-(Methoxy-d3)-L-tyrosine. Grade: ≥98%; ≥95% atom D. CAS No. 586954-09-8. Molecular formula: C10H10D3NO4. Mole weight: 214.23. | |
| L-3-PHOSPHATIDYLETHANOLAMINE,1-ACYL-2-[1-14C]ARACHIDONYL | L-3-PHOSPHATIDYLETHANOLAMINE,1-ACYL-2-[1-14C]ARACHIDONYL. Product ID: ACMA00005101. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| L-3-Trans-Hydroxyproline | L-3-Trans-Hydroxyproline. CAS No. 4298-8-2. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  |
| L-4,5,6,7-Tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid | L-4,5,6,7-Tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid. Group: Biochemicals. Alternative Names: Spinacine. Grades: Highly Purified. CAS No. 59981-63-4. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences. | Worldwide |
| L-4,5,6,7-Tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid | L-4,5,6,7-Tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid. Synonyms: Spinacine. Grade: ≥ 98% (Titration). CAS No. 59981-63-4. Molecular formula: C7H9N3O2. Mole weight: 167.17. | |
| L-4,5,6,7-Tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid 99+% | L-4,5,6,7-Tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| L-4-Carbamoylphenylalanine | L-4-Carbamoyl phenyl alanine. Group: Biochemicals. Alternative Names: (2S) -2-Amino-3- (4-carbamoylphenyl) propanoic acid. Grades: Highly Purified. CAS No. 223593-04-2. Pack Sizes: 250mg, 500mg, 1g, 2g. US Biological Life Sciences. | Worldwide |
| L-4-Chlorophenylalanine methyl ester hydrochloride | L-4-Chlorophenylalanine methyl ester hydrochloride. Group: Biochemicals. Alternative Names: Methyl 4-chloro-L-phenylalaninate hydrochloride. Grades: Highly Purified. CAS No. 63024-26-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences. | Worldwide |
| L-4-Chlorophenylalanine methyl ester hydrochloride 99+% (HPLC) | L-4-Chlorophenylalanine methyl ester hydrochloride 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 63024-26-0. Pack Sizes: 100mg, 250mg, 25mg, 1g. US Biological Life Sciences. | Worldwide |
| L-4-Oxalysine hydrochloride | L-4-Oxalysine hydrochloride is a natural product isolated from the culture media of Streptomyces roseovirdofuscus in China which has shown antitumor activities. Uses: Scientific research. Category: Signaling pathways. CAS No. 118021-35-5. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00097. |  |
| L-4-Oxalysine hydrochloride | L-4-oxalysine is a natural product isolated from a new species of Streptomyces roseoÍiridofuscus n.sp. in China. L-4-oxalysine inhibits the proliferation of some mouse implanted tumors and pulmonary metastasis of mouse Lewis lung carcinoma. Synonyms: (2S)-2-amino-3-(2-aminoethoxy)propanoic acid; hydrochloride. CAS No. 118021-35-5. Molecular formula: C5H13ClN2O3. Mole weight: 184.62. | |
| L-4-Thiazolidinecarboxylic acid | L-4-Thiazolidinecarboxylic acid. Uses: For analytical and research use. Alternative Names: L-Thiaproline. CAS No. 34592-47-7. Molecular formula: C4H7NO2S. Mole weight: 133.17. Catalog: APB34592477. |  |
| L-4-trans-Hydroxyproline benzyl ester hydrochloride | L-4-trans-Hydroxyproline benzyl ester hydrochloride. Synonyms: L-Hyp-OBzl HCl. Grade: ≥ 99% (HPLC). CAS No. 62147-27-7. Molecular formula: C12H15NO3·HCl. Mole weight: 257.73. | |
| L-4-trans-Hydroxyproline benzyl ester hydrochloride | L-4-trans-Hydroxyproline benzyl ester hydrochloride. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| L-4-trans-Hydroxyproline ethyl ester hydrochloride | L-4-trans-Hydroxyproline ethyl ester hydrochloride. Group: Biochemicals. Alternative Names: L-Hyp-OEt·HCl; (2S,4R)-(-)-Ethyl 4-hydroxy-2-pyrrolidin-carboxylate hydrochloride. Grades: Highly Purified. CAS No. 33996-30-4. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| L-4-trans-Hydroxyproline ethyl ester hydrochloride | L-4-trans-Hydroxyproline ethyl ester hydrochloride. Synonyms: L-Hyp-OEt HCl; (2S,4R)-(-)-Ethyl 4-hydroxy-2-pyrrolidin-carboxylate hydrochloride. Grade: ≥ 99% (HPLC). CAS No. 33996-30-4. Molecular formula: C7H13NO3·HCl. Mole weight: 195.62. | |
| L-4-trans-Hydroxyproline ethyl ester hydrochloride 99+% (HPLC) | L-4-trans-Hydroxyproline ethyl ester hydrochloride 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| L-4-trans-Hydroxyproline methyl ester hydrochloride | H-Hyp-OMe hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Synonyms: L-Hyp-OMe HCl. Grade: ≥ 97% (HPLC). CAS No. 40216-83-9. Molecular formula: C6H12ClNO3. Mole weight: 181.62. | |
| L-4-trans-Hydroxyproline methyl ester hydrochloride ≥97% (HPLC) | L-4-trans-Hydroxyproline methyl ester hydrochloride ≥97% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| L-4-Trifluoromethylphe | L-4-Trifluoromethylphe. Molecular formula: C10H10F3NO2. Mole weight: 233.19. | |
| L524-0366 | L524-0366 Inhibitor. Uses: Scientific use. Product Category: T8570. CAS No. 951612-19-4. |  |
| L524-0366 | L524-0366 is a specific, dose-dependent TWEAK-Fn14 inhibitor. L524-0366 specifically binds to the Fn14 surface with a KD of 7.12 μM, competitively inhibiting the binding of Fn14 to TWEAK (inhibition rate reaching 16%). L524-0366 inhibits TWEAK-induced glioma cell migration without potential cytotoxic effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 951612-19-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113763. | |
| L57 | L57 is a low-density lipoprotein receptor-related protein 1 (LRP1)-binding peptide. L57 exhibits high affinity for LRP1, with an EC50 of 45 nM. L57 possesses blood-brain barrier (BBB) permeability and plasma stability. L57 can serve as a carrier for central nervous system drug delivery[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2378836-93-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P10502. | |
| L-5 Hydroxytryptophan | L-5 Hydroxytryptophan. |  CA, FL & NJ |
| L-5-Hydroxytryptophan | L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist[1]. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia[2][3][4][5]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: L-5-HTP; Oxitriptan. CAS No. 4350-9-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-B1716. | |
| L-5-Hydroxytryptophan-d3 | L-5-Hydroxytryptophan-d3 is the deuterium labeled L-5-Hydroxytryptophan. L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist[1]. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia[2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-5-HTP-d3; Oxitriptan-d3. CAS No. 1276197-29-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B1716S. | |
| L-5-Hydroxytryptophan-d4 | L-5-Hydroxytryptophan-d4 (L-5-HTP-d4; Oxitriptan-d4) is a deuterium labeled L-5-Hydroxytryptophan (HY-B1716). L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist[1]. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia[2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-5-HTP-d4; Oxitriptan-d4. CAS No. 1246818-91-6. Pack Sizes: 5 mg. Product ID: HY-B1716S2. | |
| L5K5W6 | L5K5W6 is a synthetic antibacterial peptide. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Lys-Lys-Leu-Leu-Lys-Trp-Leu-Lys-Lys-Leu-Leu-NH2. Grade: 96.3%. Molecular formula: C71H128N18O11. Mole weight: 1409.92. | |
| L-5-Methyltetrahydrofolate calcium | L-5-Methyltetrahydrofolate calcium. Group: Biochemicals. Alternative Names: Calcium levomefolate; N-[4-[[ (2-Amino-1, 4, 5, 6, 7, 8-hexahydro-5-methyl-4-oxo-6-pteridinyl) methyl]amino]benzoyl]-L-glutamic acid calcium salt. Grades: Highly Purified. CAS No. 151533-22-1. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C20H23N7O6·Ca. US Biological Life Sciences. | Worldwide |
| L-5-Methyltetrahydrofolate Calcium | L-5-Methyltetrahydrofolate Calcium. CAS No. 151533-2-1. Categories: levomefolate calcium; 151533-22-1. | CA, FL & NJ |
| L67 | L67 (DNA Ligase Inhibitor) is a competitive DNA ligase inhibitor that effectively inhibits DNA ligases I/III (both IC50 are 10 μM). L67 can cause nuclear DNA damage by reducing levels of mitochondrial DNA and increasing levels of mitochondrially-generated ROS. L67 also activates the Caspase 1-dependent apoptosis pathway in cancer cells, can be used in cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DNA Ligase Inhibitor. CAS No. 325970-71-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15586. | |
| L-671776 | L-671776 is a myo-inositol monophosphatase (IMPase) inhibitor produced by Memnoniella echinata. Synonyms: L 671776; 4,6'-dihydroxy-6-(hydroxymethyl)-2',5',5',8a'-tetramethyl-3',4',4a',5',6',7',8',8a'-octahydro-2'H,3H-spiro[benzofuran-2,1'-naphthalene]-5-carbaldehyde; L-671,776; Spiro(benzofuran-2(3H),1'(2'H)-naphthalene)-5-carboxaldehyde, 3',4',4'a,5',6',7',8',8'a-octahydro-4,6'-dihydroxy-6-(hydroxymethyl)-2',5',5',8'a-tetramethyl-. Grade: >98%. CAS No. 134313-74-9. Molecular formula: C23H32O5. Mole weight: 388.50. | |
| L-681176 | L-681176 is originally isolated from Streptomyces sp. MA 5143a. It has the activity of inhibiting angiotensin transferase. Synonyms: L-681,176. CAS No. 91386-17-3. Molecular formula: C12H23N5O7. Mole weight: 349.34. | |
| L-681217 | A glycolipid-type antibiotic related to the efrotomycin class; isolated from a streptomyces sp.; shows broad spectrum antibiotic activity against gram positive and gram negative bacteria. Synonyms: L 681217; Antibiotic L-681217; 2,4,6-Heptatrienoic acid, 7-(tetrahydro-3-hydroxy-5-(2-methoxy-1,3-dimethyl-7-((1-oxo-2-(tetrahydro-2,4,5-trihydroxy-5-methyl-6-(1,3-pentadienyl)-2H-pyran-2-yl)butyl)amino)-3,5-heptadienyl)-2-furanyl)-. Grade: >95% by HPLC. CAS No. 93522-10-2. Molecular formula: C36H53NO10. Mole weight: 659.80. | |
| L-685458 | L-685458 is a potent transition state analog (TSA) γ-secretase inhibitor (GSI). L-685458 inhibits amyloid β-protein precursor γ-secretase activity with IC50 of 17 nM, shows greater than 50-100-fold selectivity over other aspartyl proteases tested. L685458 inhibits γ-secretase-mediated cleavage of APP-C99 and Notch-100 with IC50s of 301.3 nM and 351.3 nM, respectively. L-685458 can be used for the research of alzheimers disease (AD) and cancers[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-685,458. CAS No. 292632-98-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19369. | |
| L687 | L687 is a potent activator of TRPC3/C6/C7 that can induce cellular uptake of oligonucleotides[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2776151-36-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161766. | |
| L 687781 | L 687781, an inhibitor of β-1,3-D-glucan synthase, is originally isolated from Dictyochaeta simplex. It also has anti-Candida fungal activity and has some effects on Pneumocystis carinii. Synonyms: Hexopyranose, 1,6'-anhydro-1-C-(2,4-dihydroxy-6-(hydroxymethyl)phenyl)-4-O-(6-O-(8-hydroxy-1-oxo-2,4-decadienyl)hexopyranosyl)-, 3-(7-hydroxy-8,14-dimethyl-1-oxo-2,4,6,8,10-hexadecapentaenoate). CAS No. 130304-58-4. Molecular formula: C47H66O17. Mole weight: 903.01. | |
| L-690330 | L-690330 is a competitive inhibitor of inositol monophosphatase (IMPase) with Kis of 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase, respectively. L-690330 exhibits 10-fold more sensitive than mouse and rat IMPase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 142523-38-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101075. | |
| L-692,585 | L-692,585. Group: Biochemicals. Grades: Purified. CAS No. 145455-35-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| L-694247 | L-694247 is a selective 5-HT1D agonist with the pIC50 values of 10.03, 8.64, 6.42, and 5.66 for 5-HT1D, 5-HT1A, 5-HT1C, and 5-HT1E receptors , respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 137403-12-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-101208. | |
| L-696474 | L-696474 is extracted from Hypoxylon fragiforme MF5511. It can competitively inhibit the action of HIV-1 protease with an IC50 of 3 μmol/L. Synonyms: L-696,474; 18-dehydroxycytochalasin H. Grade: >98% by HPLC. CAS No. 141994-72-1. Molecular formula: C30H39NO4. Mole weight: 477.63. | |
| L-701324 | L-701324 is a potent, orally active NMDA receptor antagonist that antagonizes the activity of the NMDA receptor by blocking its glycine B binding site. L-701324 binds with high affinity to rat brain membranes (IC50=2 nM). L-701324 has antidepressant activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 142326-59-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18698. | |
| L-701,324 (7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone) | A highly potent and selective antagonist for thenMDA receptor glycine site (IC50 = 2.0nM; Kd = 28nM; ED50 = 0.9nM either intraperitoneal (ip) or oral (po) adminited). The first such compounds with significant activity in the central nervous system following oral dosing and a potent, active anticonvulsant with a reduced propensity to activate mesolimbic dopaminergic systems in rodents. Group: Biochemicals. Grades: Highly Purified. CAS No. 142326-59-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| L-733060 hydrochloride | L-733060 hydrochloride is a selective neurokinin-1 (NK-1) receptor antagonist. L-733060 hydrochloride mainly regulates pain transmission and neural plasticity by blocking the binding of Substance P (P substance) to the NK-1 receptor. L-733060 hydrochloride blocks the promoting effect of Substance P on long-term potentiation (LTP) in the hippocampus. L-733060 hydrochloride reverses the orofacial hyperalgesia induced by experimental occlusal interference (EOI) in rats. L-733060 hydrochloride hydrochloride inhibits neurogenic plasma extravasation at a dose that does not cause adverse cardiovascular effects in rodents, and also acts as an anti-tumor agent. L-733060 hydrochloride can be used for the study of chronic orofacial pain[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 148687-76-7. Pack Sizes: 1 mg. Product ID: HY-14406A. | |
| L-741626 | L-741626 is a selective D2 dopamine receptor antagonist, with the Ki values of 2.4, 100 and 220 nM for human D2, D3 and D4 receptors respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 81226-60-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-101348. | |
| L-745870 | L-745870 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 158985-00-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14325. | |
| L-745870 hydrochloride | L-745870 hydrochloride is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 hydrochloride shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1173023-36-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14325B. | |
| L-745,870 Trihydrochloride (Dopamine D4 Receptor Antagonist, L-745,870 Trihydrochloride, L-745870, L745870) | Selective D4 receptor antagonist with excellent brain penetration. Displays an affinity (Ki) of 0.4nM for human D4 receptors with >1000-fold binding selectivity over D2 and D3 receptors. Does not block agonist-induced activation of GIRK currents. It is used frequently in retinal and CNS studies of D4 modulation. Group: Biochemicals. Grades: Highly Purified. CAS No. 158985-00-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| L748337 | L748337 is a potent β3-adrenergic receptor antagonist and displays selectivity over β1 and β2 receptors. The Ki values of L748337 for β3-, β2- and β1-adrenoceptors are 4.0 nM, 204 nM and 390 nM, respectively[1]. L748337 couples predominantly to Gi to activate MAPK signaling and increases phosphorylation of Erk1/2 with pEC50 value of 11.6[2]. L748337 can be used for the research of cancer, nonalcoholic fatty liver disease (NAFLD), and cardiovascular related diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 244192-94-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103211. | |
| L-750,667 trihydrochloride | L-750,667 trihydrochloride. Alternative Names: L-750,667 trihydrochloride, 3-[4-(4-Iodophenyl)piperazin-1-yl]methyl-1H-pyrrolo[2,3-b]pyridine trihydrochloride, NCGC00094070-01, EU-0100722, AGN-PC-00IQTF, L133_SIGMA, CHEMBL1496166, CTK8G0467, AG-L-65892, LP00722, L-133, ( inverted question mark)-3-[4-Iodophenyl)-1-piperazyl] methylpyrrolo [2,3-b] pyrimidine, 3-[[4-(4-iodophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine;trihydrochloride, 1021868-80-3. CAS No. 1021868-80-3. Purity: 96%. Product ID: ACM1021868803. Molecular formula: C18H22Cl3IN4. Mole weight: 527.66. IUPAC Name: 3-[[4-(4-iodophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine;trihydrochloride. Alfa Chemistry - ISO 9001:32057 Certified. | |
| L755507 | L755507 is a potent, selective agonist of β3-AR with an IC50 of 35 nM. L755507 enhances the homology-directed repair (HDR)-mediated genome editing[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 159182-43-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-19334. | |
| L-755,507 | Potent beta3-adrenergic receptor partial agonist > 1000-fold selective over beta1- and beta2-adrenoceptors (EC50 values are 0.43, 580 and > 10000 nM for activation of cloned human beta3-, beta1- and beta2-adrenoceptors respectively). Stimulates lipolysis in rhesus adipocytes in vitro (EC50 = 3.9nM). Enhances CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs). Group: Biochemicals. Alternative Names: 4- [ [ (Hexylamino) carbonyl] amino] -N- [4- [2- [ [ (2S) -2-hydroxy-3- (4-hydroxyphenoxy) propyl] amino] ethyl] phenyl] benzenesulfonamide; (S) -4- [ [ (Hexylamino) carbonyl] amino] -N- [4- [2- [ [2-hydroxy-3- (4-hydroxyphenoxy) propyl] amino] ethyl] phenyl] benzenesulfonamide. Grades: Highly Purified. CAS No. 159182-43-1. Pack Sizes: 10mg, 50mg. Molecular Formula: C??H??N?O?S, Molecular Weight: 584.73. US Biological Life Sciences. | Worldwide |
| L 760735 | L 760735. Group: Biochemicals. Grades: Purified. CAS No. 188923-01-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| L-778123 | L-778123 is a dual FPTase and GGPTase-I inhibitor, with IC50s of 2 nM and 98 nM respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 183499-57-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16273. | |
| L-778123 hydrochloride | L-778123 hydrochloride is a dual inhibitor of FPTase and GGPTase-I, with IC50 values of 2 nM and 98 nM respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 253863-00-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16273A. | |
| L-779,450 | L-779,450. Group: Biochemicals. Grades: Purified. CAS No. 303727-31-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| L-783277 | L-783277 is originally isolated from Phoma sp. It inhibits MEK2 with an IC50 of 4 nmol/L. Synonyms: (3S,5Z,8S,9S)-3,4,9,10,11,12-Hexahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione; LL-783277. Grade: ≥95%. CAS No. 791807-02-8. Molecular formula: C19H24O7. Mole weight: 364.39. | |
| L-796778 acetate | L-796778 acetate is a selective agonist of the sst3 receptor. In CHO-K1 cells expressing the hsst3 receptor, L-796778 acetate is a partial agonist that inhibits Forskolin (HY-15371)-stimulated cAMP production with an IC50 value of 18 nM. L-796778 acetate has anticonvulsant effect[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2922280-21-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-123335A. | |
| L-798106 | L-798106 is potent and highly selective prostanoid EP3 receptor antagonist (Ki=0.3 nM), it also has micromolar activities at the EP4, EP1 and EP2 receptors with Ki values of 916 nM, >5000 nM and >5000 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CM9; GW671021. CAS No. 244101-02-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15274. | |
| L-803087 | L-803087 is a potent and selective somatostatin sst4 receptor agonist with a Ki of 0.7 nM. L-803087 is >280-fold higher than other somatostatin receptors. L-803087 facilitates AMPA-mediated hippocampal synaptic responses in vitro and increases kainate-induced seizures in mice[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 217480-26-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108497. | |
| L-803,087 trifluoroacetate | L-803,087 trifluoroacetate. Group: Biochemicals. Grades: Purified. CAS No. 217480-26-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| L-817818 | L-817818 is a potent and subtype-selective agonist of the somatostatin receptor. L-817818 provides a direct approach to defining somatostatin receptor physiological functions[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 217480-27-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108498. | |
| L82 | L82 is a selective and uncompetitive DNA ligase 1 (DNA Lig1) inhibitor (hLig1 IC50=12 μM). L82 shows anti-proliferative activity to breast cancer cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 329227-30-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15587. | |
| L-826266 | L-826266 is a selective and competitive EP3 receptor antagonist. L-826266 can be used for convulsive disorders research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 244101-03-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19361. | |
| L82-G17 | L82-G17 is an uncompetitive DNA ligase I (Lig I)-selective inhibitor. L82-G17 inhibits the third step of the ligation reaction, phosphodiester bond formation. L82-G17can be used as a probe of the catalytic activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 92285-87-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148161. | |
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