A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
L-771688, also known as SNAP 6383, is a new potent and highly selective α1A-adrenoceptor antagonist with 500-fold selective over α1B and α1D-adrenoceptors. Synonyms: methyl (4S)-4-(3,4-difluorophenyl)-6-(methoxymethyl)-2-oxo-3-[3-(4-pyridin-2-ylpiperidin-1-yl)propylcarbamoyl]-1,4-dihydropyrimidine; 5-carboxylate; L 771,688; L 771688; L-771,688; L-771688; methyl 4-(3,4-difluorophenyl)-6-((methyloxy)methyl)-2-oxo-3-((((3-(4-2-pyridinyl)-1-piperidinyl)propyl)amino)carbonyl)-1,2,3,4; tetrahydro-5-pyrimidinecarboxylate; SNAP 6383; SNAP-6383. CAS No. 200050-59-5. Molecular formula: C28H33F2N5O5. Mole weight: 557.59.
L-778123
L-778123 is an inhibitor of FPTase and GGPTase-I, which was developed in part because it can completely inhibit Ki-Ras prenylation. The combination ofL-778,123 and radiotherapy at dose level 1 showed acceptable toxicity in patients with locally advanced pancreatic cancer. Radiosensitization of a patient-derived pancreatic cancer cell line was observed. Synonyms: L778,123; L-778,123; L 778,123; L 778123; L778123; 1-(3-chlorophenyl)-4-[1-(4-cyanobenzyl)-5-imidazolyl methyl]-2-piperazinone. CAS No. 183499-57-2. Molecular formula: C22H20ClN5O. Mole weight: 405.88.
L-778123
L-778123 is a dual FPTase and GGPTase-I inhibitor, with IC 50 s of 2 nM and 98 nM respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 183499-57-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16273.
L-778123 HCl
L-778123 is an inhibitor of FPTase and GGPTase-I, which was developed in part because it can completely inhibit Ki-Ras prenylation. Synonyms: 4-((5-((4-(3-chlorophenyl)-3-oxopiperazin-1-yl)methyl)-1H-imidazol-1-yl)methyl)benzonitrile hydrochloride; L778123; L-778123; L 778123; L778,123; L-778,123; L 778,123 HCl. Grades: 98%. CAS No. 253863-00-2. Molecular formula: C22H20ClN5O. Mole weight: 405.88.
L-778123 hydrochloride
L-778123 hydrochloride is a dual inhibitor of FPTase and GGPTase-I , with IC 50 values of 2 nM and 98 nM respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 253863-00-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16273A.
L-779450
Raf kinase inhibitor, a potential treatment for neurotraumatic diseases. Its effects also suppress DNA synthesis and induce apoptosis in targeted cells, presenting new applications in treating certain types of cancers. Group: Biochemicals. Alternative Names: 2-Chloro-5-[2-phenyl-5-(4-pyridinyl)-1H-imidazol-4-yl]phenol; 4-(4-Chloro-3-hydroxyphenyl)-2-phenyl-5-(4-pyridyl)-1H-imidazole. Grades: Highly Purified. CAS No. 303727-31-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
L-779450
L-779450 is a potent, selective and ATP-competitive Raf kinase inhibitor (IC50 = 10 nM). L-779450 suppresses DNA synthesis and induces apoptosis in cells that proliferate in response to Raf-1 and A-Raf but not B-Raf. Synonyms: L-779450; L779450; L 779450; L-779,450; L 779,450; L779,450. Grades: >98%. CAS No. 303727-31-3. Molecular formula: C20H14ClN3O. Mole weight: 347.8.
L-779,450. Group: Biochemicals. Grades: Purified. CAS No. 303727-31-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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L-783277
L-783277 is originally isolated from Phoma sp. It inhibits MEK2 with an IC50 of 4 nmol/L. Synonyms: (3S,5Z,8S,9S)-3,4,9,10,11,12-Hexahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione; LL-783277. Grades: ≥95%. CAS No. 791807-02-8. Molecular formula: C19H24O7. Mole weight: 364.39.
L791943
L791943 is a highly potent and metabolically stable PDE4 inhibitor with good in vitro activity (IC50= 4.2 nM). L-791, 943 is potent in vitro and in vivo as demonstrated by the inhibition of antigen-induced bronchoconstriction in a variety of models.The compound is well absorbed and is well tolerated in the ferret. Synonyms: L791943; L 791943; L-791943; 2-[4-[1-[3,4-bis(difluoromethoxy)phenyl]-2-(1-oxidopyridin-1-ium-4-yl)ethyl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol; L-791,943; L-791943. CAS No. 192767-01-4. Molecular formula: C24H17F10NO4. Mole weight: 573.38.
L-798106
L-798106 is potent and highly selective prostanoid EP3 receptor antagonist (Ki=0.3 nM), it also has ?micromolar activities at the EP4, EP1 and EP2 receptors with Ki values of 916 nM, >5000 nM and >5000 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CM9; GW671021. CAS No. 244101-02-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15274.
L-798106 is a potent and selective prostanoid receptor EP3-selective antagonists. L-798106 has been used in multiple studies to tease out EP3 agonist activity, both in vitro and in vivo. L-798106 successfully blocks the actions of sulprostone, an EP3-selective agonist. L-798106 was useful in showing that the vascular contraction effect of PGE2 is due to its prostanoid EP3 agonist activity. Group: Biochemicals. Alternative Names: (2E) -N-[ (5-Bromo-2-methoxyphenyl) sulfonyl]-3-[2- (2-naphthalenylmethyl) phenyl]-2-propenamide; CM 9; GW 671021. Grades: Highly Purified. CAS No. 244101-02-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
L-798,106
L-798,106 is a potent and highly selective prostanoid receptor EP3 antagonist wth Ki value of 0.3 nM. It is used in prostanoid receptor signaling studies that regulates the central excitatory effects of PGE(2) and COX-2 levels on PVN neurons. It has been used to tease out EP3 agonist activity both in vitro and in vivo. It successfully blocks the EP3 agonist activity of sulprostone on guinea pig vas deferens and trachea at 0.2 μM. It attenuates sulprostone-induced inhibition of EFS-evoked twitch and contractile responses in vivo. Synonyms: L-798,106; L 798,106; L798,106. N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide; L-798106; (2E)-N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide; CM 9; GW 671021; (E)-N-(5-bromo-2-methoxyphenyl)sulfonyl-3-[2-(naphthalen-2-ylmethyl)phenyl]prop-2-enamide. Grades: ≥99% by HPLC. CAS No. 244101-02-8. Molecular formula: C27H22BrNO4S. Mole weight: 536.44.
L-798,106
L-798,106. Group: Biochemicals. Grades: Purified. CAS No. 244101-02-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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L-803,087 trifluoroacetate
L-803,087 trifluoroacetate. Group: Biochemicals. Grades: Purified. CAS No. 217480-26-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
L-803,087 trifluoroacetate
L-803,087 trifluoroacetate is the trifluoroacetate salt of L-803,087, which is a selective and potent somatostatin sst4 receptor agonist often overexpressed in tumours. Its Ki value is 0.7 nM for cloned human sst4. It is a potential therapeutic target. It can be used to study signaling pathways related to somatostatin receptors. It increases kainate-induced seizures in mice in vivo and facilitates AMPA-mediated hippocampal synaptic responses in vitro. Synonyms: L-803,087 trifluoroacetate; L 803,087 trifluoroacetate; L803,087 trifluoroacetate; N2-[4-(5,7-Difluoro-2-phenyl-1H-indol-3-yl)-1-oxobutyl]-L-arginine methyl ester trifluoroacetate. Grades: ≥97% by HPLC. CAS No. 217480-26-7. Molecular formula: C27H30F5N5O5. Mole weight: 599.56.
L-817,818
L-817,818. Group: Biochemicals. Grades: Purified. CAS No. 217480-27-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
L-817,818
L-817,818 is a selective and potent somatostatin sst5 receptor agonist with Ki value of 0.4 nM for cloned human sst5 receptors. It inhibits insulin release from mouse pancreatic islets and growth hormone release from rat pituitary cells and in vitro. Synonyms: L-817,818; L 817,818; L817,818. N2-[[2-(2-Naphthalenyl)-1H-benz[g]indol-3-yl]acetyl-D-lysine (2S)-2-aminopropyl ester; L817818; [(2S)-2-aminopropyl] (2S)-6-amino-2-[[2-(2-naphthalen-2-yl-1H-benzo[g]indol-3-yl)acetyl]amino]hexanoate. Grades: ≥99% by HPLC. CAS No. 217480-27-8. Molecular formula: C33H36N4O3. Mole weight: 536.67.
L82
L82 is a selective and uncompetitive DNA ligase 1 ( DNA Lig1 ) inhibitor (hLig1 IC 50 =12 μM). L82 shows anti-proliferative activity to breast cancer cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 329227-30-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15587.
L-826,266
L-826,266 is a potent and selective EP3 receptor antagonist. Synonyms: (E)-N-(5-Bromo-2-methoxyphenyl)sulfonyl-3-[5-chloro-2-(naphthalen-2-ylmethyl)phenyl]prop-2-enamide. Grades: ≥98%. CAS No. 244101-03-9. Molecular formula: C27H21BrClNO4S. Mole weight: 570.9.
L82-G17
L82-G17 is an uncompetitive DNA ligase I (Lig I)-selective inhibitor. L82-G17 inhibits the third step of the ligation reaction, phosphodiester bond formation. L82-G17can be used as a probe of the catalytic activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 92285-87-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148161.
L-838417
L-838417. Group: Biochemicals. Alternative Names: 3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4,-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine. Grades: Highly Purified. CAS No. 286456-42-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C19H19F2N7O. US Biological Life Sciences.
L-838,417 is a subtype-selective GABAA receptor partial agonist. It selectively binds to α2, α3 and α5 subunits with Ki values of 0.67, 0.67 and 2.25 nM respectively, but it shows no efficacy at α1 (α1-sparing). It shows non-sedative antinociceptive, anxiolytic and anti-inflammatory activity in vivo. It was developed by Merck. Uses: Gaba-a receptor agonists. Synonyms: L838417; L 838417; L-838417; 3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine; 5-({[7-tert-butyl-3-(2,5-difluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]oxy}methyl)-1-methyl-1H-1,2,4-triazole; L-838417. Grades: ≥98% by HPLC. CAS No. 286456-42-6. Molecular formula: C19H19F2N7O. Mole weight: 399.40.
A ligand of GABAA receptors. Group: Biochemicals. Alternative Names: 3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4,-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
L-858,051 hydrochloride
L-858,051 is a water-soluble analog of forskolin that acts as an adenylate cyclase activator. It inhibited the 5-HT-stimulated inositol phosphate (IP) accumulation in canine cultured aorta smooth muscle cells (ASMCs). Synonyms: [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] 4-(4-methylpiperazin-1-yl)butanoate dihydrochloride. Grades: ≥95%. CAS No. 115116-37-5. Molecular formula: C29H50N2O8·2HCl. Mole weight: 609.6.
L-869298
L-869298 is a high potent and selective PDE4 inhibitor, acts as a Type 4 cyclic nucleotide phosphodiesterase inhibitor. Uses: Type 4 cyclic nucleotide phosphodiesterase inhibitor. Synonyms: L-869298; L-869298; L-869298; (S)-L-869298. 2-Thiazolemethanol, 5-((1S)-1-(3-(cyclopropyloxy)-4-(difluoromethoxy)phenyl)-2-(1-oxido-3-pyridinyl)ethyl)-alpha,alpha-bis(trifluoromethyl)-. Grades: ≥98%. CAS No. 362718-73-8. Molecular formula: C23H18F8N2O4S. Mole weight: 570.45.
L-902688
L-902688 is a potent, selective and orally active EP4 receptor agonist with a Ki of 0.38 nM and an EC50 of 0.6 nM. L-902688 shows >4,000-fold selective for EP4 over other EP and prostanoid receptors[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 634193-54-7. Pack Sizes: 1 mg (11.92 mM * 200 ?L in Methanol). Product ID: HY-119163.
L-902,688
L-902,688 is a highly potent agonist of the human PGE2 receptor subtype EP4. It attenuated right ventricular fibrosis in a monocrotaline (MCT)-induced pulmonary arterial hypertension (PAH) rat model. L-902,688 exhibits a neuroprotective effect on ischemic stroke by reducing MMP-3/-9 and BBB damage. Synonyms: (5R)-5-[(E,3R)-4,4-difluoro-3-hydroxy-4-phenylbut-1-enyl]-1-[6-(2H-tetrazol-5-yl)hexyl]pyrrolidin-2-one. Grades: ≥98%. CAS No. 634193-54-7. Molecular formula: C21H27F2N5O2. Mole weight: 419.5.
L-9-Anthrylalanine
L-9-Anthrylalanine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: D-9-AnthrylaAlanine;D-3-(9-ANTHRYL)ALANINE;D-9-ANTHRYLALANINE. Product Category: Heterocyclic Organic Compound. CAS No. 135092-49-8. Molecular formula: C17H15NO2. Product ID: ACM135092498. Alfa Chemistry ISO 9001:2015 Certified.
LA-1
LA-1 is an aliphatic unsaturated ketonic acid produced by Streptomyces kitasatoensis NU-4-4-2. It has anti-gram-positive bacteria activity. CAS No. 61947-93-1. Molecular formula: C10H10O3. Mole weight: 178.18.
L-a-Aminoadipic Acid
≥98%. Group: Biochemicals. Alternative Names: L-2-Aminohexanedioic acid. Grades: Reagent Grade. CAS No. 1118-90-7. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
L-a-Aminoadipic acid 98+%
L-a-Aminoadipic acid 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g, 250g. US Biological Life Sciences.
Worldwide
L-a-Aminoadipic acid δ-methyl ester hydrochloride
L-a-Aminoadipic acid δ-methyl ester hydrochloride. Group: Biochemicals. Alternative Names: L-Aad(OMe)-OH·HCl; L-2-Aminohexanedioic acid δ-methyl ester hydrochloride. Grades: Highly Purified. CAS No. 147780-39-0. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C7H13NO4·HCl. US Biological Life Sciences.
Useful intermediate for the synthesis of optically active amino acids. Group: Biochemicals. Alternative Names: (S)-a-Aminoxy-b-phenylpropionic Acid, Hydrobromide. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
L-a-Asparagine,N-[(phenylmethoxy)carbonyl]-L-tyrosyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Z (CARBOBENZOXY)-TYR-VAL-ALA-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC;Z-TRY-VAL-ALA-ASP-AFC;Z-TYR-VAL-ALA-ASP-AFC;Z-YVAD-AFC;CASPASE-1 SUBSTRATE (AFC);CASPASE-1, SUBSTRATE, FLUOROGENIC;CASPASE-1 SUBSTRATE VI, FLUOROGENIC. Product Category: Heterocyclic Organic Compound. CAS No. 201608-13-1. Molecular formula: C39H40F3N5O11. Mole weight: 811.76. Purity: 0.96. IUPACName: (3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-3-(4-hydroxyphenyl)-2-(phenylmethoxycarbonylamino)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-oxo-4-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]butanoic acid. Canonical SMILES: CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)NC1=CC2=C(C=C1)C(=CC(=O)O2)C(F)(F)F)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)OCC4=CC=CC=C4. Product ID: ACM201608131. Alfa Chemistry ISO 9001:2015 Certified.
labdatriene synthase
The enzyme from rice (Oryza sativa), expressed in Escherichia coli, also produces ent-sandaracopimara-8(14),15-diene from ent-copalyl diphosphate, another naturally occuring copalyl isomer in rice (cf. ent-sandaracopimaradiene synthase, EC 4.2.3.29). Group: Enzymes. Synonyms: OsKSL10 (gene name). Enzyme Commission Number: EC 4.2.3.99. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5263; labdatriene synthase; EC 4.2.3.99; OsKSL10 (gene name). Cat No: EXWM-5263.
Labetalol
Labetalol (AH5158) is an orally active selective α1- and non-selective β-adrenergic receptors competitive antagonist. Labetalol, an anti-hypertensive agent, can be used for the research of cardiovascular disease, such as hypertension in pregnancy [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AH5158; Sch-15719W free base. CAS No. 36894-69-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121383.
Labetalol-1-carboxylic Acid Methyl Ester
An impurity of Labetalol, a beta blocker used to treat high blood pressure. Synonyms: Methyl labetalol acid; Labetalol Impurity B. CAS No. 802620-01-5. Molecular formula: C20H25NO4. Mole weight: 343.4.
Labetalol HCl (Mixture of Diastereomers)
Cas No. 32780-64-6.
Labetalol hydrochloride
Labetalol hydrochloride is a mixed alpha/beta adrenergic antagonist that is used to treat high blood pressure. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AH-5158 hydrochloride; Sch-15719W. CAS No. 32780-64-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1108.
Labetalol is a specific competitive antagonist at both α-and β-adrenergic receptor sites. Labetalol is used as an antihypertensive. Group: Biochemicals. Alternative Names: 2-Hydroxy-5-[1-hydroxy-2-[ (1-methyl-3-phenylpropyl) amino]ethyl]benzamide Hydrochloride; 5- [1-Hydroxy-2- [ (1-methyl-3-phenylpropyl) amino] ethyl] salicylamide Monohydrochloride; AH 5158 Hydrochloride; AH 5158A; Amipress; Ipolab; Labelol; Labracol; NSC 290312; Normodyne; Presdate; Pressalolo; Sch 15719W; Trandate; Vescal. Grades: Highly Purified. CAS No. 32780-64-6. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Labetalol (hydrochloride) (Standard)
Labetalol (hydrochloride) (Standard) is the analytical standard of Labetalol (hydrochloride). This product is intended for research and analytical applications. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AH-5158 hydrochloride(Standard); Sch-15719W (Standard). CAS No. 32780-64-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B1108R.
Labetalol Impurity A is an impurity of Labetalol, a medication used for the treatment of high blood pressure, and also for long term management of angina. Synonyms: Labetalol-1-carboxylic Acid; Labetalol acid; 2-Hydroxy-5-(1-hydroxy-2-((1-methyl-3-phenylpropyl)amino)ethyl)benzoic acid. Grades: ≥98%. CAS No. 1391051-99-2. Molecular formula: C19H23NO4. Mole weight: 329.40.
Labetalol IMpurity A
Labetalol IMpurity A. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Hydroxy-5-[1-hydroxy-2-[(1-Methyl-3-phenylpropyl)aMino]ethyl]benzoic Acid. Appearance: White solid. CAS No. 1391051-99-2. Molecular formula: C19H23NO4. Mole weight: 329.39. Purity: 0.98. Product ID: ACM1391051992. Alfa Chemistry ISO 9001:2015 Certified.
Labetalol Impurity B HCl (Mixture of Diastereomers)
Labetalone is an alpha- and beta-adrenergic receptor antagonist that is used as an antihypertensive. Synonyms: Labetalone HCl; 2-hydroxy-5-[2-(4-phenylbutan-2-ylamino)acetyl]benzamide hydrochloride. CAS No. 96441-14-4. Molecular formula: C19H22N2O3·HCl. Mole weight: 362.85.
Labetuzumab
Labetuzumab is a humanised anti-carcinoembryonic antigen (CEA) monoclonal antibody that inhibits tumour growth and sensitises human medullary thyroid cancer xenografts to Dacarbazine chemotherapy[1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 219649-07-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99160.
Labetuzumab
Labetuzumab is a humanized anti-carcinoembryonic antigen (CEA) monoclonal antibody with antineoplastic activity. Labetuzumab has been used as an adjuvant treatment for colorectal cancer. Synonyms: CEA-CIDE. CAS No. 219649-07-7.
Labetuzumab govitecan
Labetuzumab govitecan (IMMU 130) is an Anti- CEACAM5 / SN-38 antibody-drug conjugate (ADC). Labetuzumab govitecan consists of the antibody Labetuzumab, SN-38, and a pH-sensitive Linker. Labetuzumab govitecan can be used for research of cancers, such as colorectal cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IMMU 130; hMN-14-SN-38. CAS No. 1469876-18-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99681.
It is produced by the strain of Str. albospoeus var. labilomyceticus A955-y3. It's a sugar antibiotic. It has anti-gram-positive bacteria, mycobacterium activity. It had cytotoxic effect on HeLa cells and Yoshida sarcoma cells. Each rat (Transplantation of airy ascites carcinoma in mice) is given Labilomycin of 250 μg/d, it can inhibit tumor and prolong life. It has a protective effect on mice infected with S. aureus. Serum does not affect its antibacterial activity. Synonyms: Pulvomycin; Oxacyclodocosa-4,7,9,11,15,17,19-heptaene-2,13-dione, 22-[(1S,2S,3S,5E,7E,9E,11S,12S)-12-[(6-deoxy-2,4-di-O-methyl-β-D-galactopyranosyl)oxy]-2,11-dihydroxy-1,3-dimethyl-4-oxo-5,7,9-tridecatrien-1-yl]-6,14-dihydroxy-5,8,12-trimethyl-, (4E, 6R, 7E, 9E, 11E, 14S, 15E, 17E, 19E, 22S)-; (4E, 6R, 7E, 9E, 11E, 14S, 15E, 17E, 19E, 22S)-22-[(1S, 2S, 3S, 5E, 7E, 9E, 11S, 12S)-12-[(6-Deoxy-2, 4-di-O-methyl-β-D-galactopyranosyl)oxy]-2, 11-dihydroxy-1, 3-dimethyl-4-oxo-5, 7, 9-tridecatrien-1-yl]-6, 14-dihydroxy-5, 8, 12-trimethyloxacyclodocosa-4, 7, 9, 11, 15, 17, 19-heptaene-2, 13-dione; (-)-Pulvomycin; Antibiotic 1063Z. CAS No. 11006-66-9. Molecular formula: C47H66O13. Mole weight: 839.02.
Laboratory Briquet Press, 220V, 60Hz, 3-Ph
Laboratory Briquet Press, 220V, 60Hz, 3-Ph. Uses: For analytical and research use. Group: Equipment for sample preparation. Catalog: APS009290.