A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
LY 181984 is an antitumor sulfonylurea. Uses: Antitumor. Synonyms: LY 181984; LY-181984; LY181984; MPCU. N-(((4-chlorophenyl)amino)carbonyl)-4-methyl-Benzenesulfonamide;1-(4-chlorophenyl)-3-(4-methylphenyl)sulfonylurea. Grades: ≥98%. CAS No. 3955-50-8. Molecular formula: C14H13ClN2O3S. Mole weight: 324.78.
LY-183648
LY-183648 has antiestrogenic activity. It inhibited PAIII metastasis to the gluteal and iliac lymph nodes. Uses: Ly-183648 has antiestrogenic activity. Synonyms: LY 183648; LY183648; LY-183648. 5-[Bis(4-chlorophenyl)-imidazol-1-ylmethyl]pyrimidine; LY183648; Pyrimidine, 5-(bis(4-chlorophenyl)-1H-imidazol-1-ylmethyl)-. Grades: >98 %. CAS No. 102993-90-8. Molecular formula: C20H14Cl2N4. Mole weight: 381.26.
LY-186126
LY 186126 is a potent cGI-PDE inhibitor. It exhibit reversible and high affinity binding to a single class of SaR binding sites. Synonyms: LY 186126; LY186126; LY-186126. 1,3-Dihydro-1,3,3-trimethyl-5-[(1,4,5,6-tetrahydro-4-methyl-6-oxopyridazin)-3-yl]-2H-indol-2-one;2H-Indol-2-one, 1,3-dihydro-1,3,3-trimethyl-5-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)-;1,3,3-Trimethyl-6-(4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)indol-2-one. Grades: >98 %. CAS No. 100644-00-6. Molecular formula: C16H19N3O2. Mole weight: 285.34.
LY 186564
LY 186564 is a bio-active chemical,but no detailed information has been published yet. Synonyms: LY 186564; LY186564; LY-186564. 3-(((dipropylamino)carbonyl)oxy)- Estra-1,3,5(10)-trein-17-one. Grades: 98%. CAS No. 143982-31-4. Molecular formula: C25H35NO3. Mole weight: 397.55.
LY 186826
LY 186826 is an antibacterial agent with bicyclic pyrazolidinones containing a novel aza-γ-lactam ring structure. The properties of this compound appear to be related to those of β-lactam antibiotics, because both classes of compounds have common binding molecules such as β-lactamases and penicillin-binding proteins. Uses: Antibacterial agent. Synonyms: LY 186826; LY186826; LY-186826. AC1NUT6W; CHEMBL436143; HE187334; 6-acetyl-2-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-oxo-2,7-dihydro-1H-pyrazolo[1,2-a]pyrazole-5-carboxylic acid. Grades: 98%. CAS No. 126165-79-5. Molecular formula: C15H16N6O6S. Mole weight: 408.39.
LY 189332 is a bio-active molecular under the development of Eli Lilly as an antimetastatic drug. Uses: Antimetastatic drug. Synonyms: LY 189332; LY-189332; LY189332. N-(4-fluorophenyl)-4,4''-dimethoxy-(1,1':2',1''-Terphenyl)-4'-amine. Grades: 98%. CAS No. 123215-05-4. Molecular formula: C26H22FNO2. Mole weight: 399.46.
LY-190388
LY-190388 is an μ receptor agonist. It is a penicillamine-containing enkephalin analog and has analgesia effect. Uses: Ly-190388 has analgesia effect. Synonyms: LY 190388; LY190388; LY-190388; H-Tyr-pen-gly-phe-val-OH;Tyr-penicillamine-gly-phe-val;(2R)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-[2-[[(2S)-2-amino-3-methyl-3-sulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-methylbutanoic acid;LY190388;D-Valine, N-(N-(N-(3-mercapto-N-L-tyrosyl-D-valyl)glycyl)-L-phenylalanyl)-. Grades: >98%. CAS No. 105496-35-3. Molecular formula: C30H41N5O7S. Mole weight: 615.74.
LY 191704
LY 191704, a hexahydrobenzoquinolin derivative, has been found to be a human type I steroid 5alpha-reductase inhibitor that could be probably effective in the treatment of Alopecia and Benign prostatic hyperplasia. It was developed by Eli Lilly and had no development reports since 2001. Uses: 5-alpha reductase inhibitors. Synonyms: LY191704; LY-191704; 8-Chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2H)-one. Grades: 98%. CAS No. 146117-78-4. Molecular formula: C14H16ClNO. Mole weight: 249.74.
LY 193239
This bio-active molecular is a cell wall inhibitor as a antibacterial agent. LY 193239 has a lactam pyrazolidinone structure. Clinical trials for Bacterial infections were discontinued. Uses: Antibacterial. Synonyms: LY 193239; LY193239; LY-193239. (2S)-2-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-6-methylsulfonyl-3-oxo-2,7-dihydro-1H-pyrazolo[1,2-a]pyrazole-5-carboxylic acid. Grades: 98%. CAS No. 124986-46-5. Molecular formula: C14H16N6O7S2. Mole weight: 444.44.
LY-195448
LY-195448 is a phenethanolamine. It blocks cells at metaphase. It has shown anti-tumour activity. Uses: Ly-195448 has shown anti-tumour activity. Synonyms: LY 195448; LY195448; LY-195448; UNII-BR0DFE3GF6. (R)-4-(3-((2-Hydroxy-2-phenethyl)amino)-3-methylbutyl)benzamide monohydrochloride;4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]benzamide hydrochloride. Grades: >98%. CAS No. 111112-18-6. Molecular formula: C20H27ClN2O2. Mole weight: 362.90.
LY-201409
LY-201409 is a potent benzamide anticonvulsant. It antagonized maximal electroshock (MES)-induced seizures with ED50 values of 16.2 and 4.2 mg/kg after oral administration to mice and rats, respectively. Uses: Ly-201409 has anticonvulsant effect. Synonyms: LY 201409; LY201409; LY-201409. 4-Amino-N-(2,6-dimethylphenyl)-3,5-dimethylbenzamide;Benzamide, 4-amino-N-(2,6-dimethylphenyl)-3,5-dimethyl-. Grades: >98%. CAS No. 109306-94-7. Molecular formula: C17H20N2O. Mole weight: 268.36.
LY 203647 is a a leukotriene D4 and E4 receptor antagonist with a tetrazole nucleus structure originated by Eli Lilly. No development for treatment of Ischaemic heart disorders by LY 203647 has been reported yet. Uses: Ischaemic heart disorders. Synonyms: LY 203647; LY203647; LY-203647; 1-(2-hydroxy-3-propyl-4-(4-(2-(4-(1H-tetrazol-5-yl)butyl)-2H-tetrazol-5-yl)butoxy)phenyl)-Ethanone. Grades: 98%. CAS No. 122009-61-4. Molecular formula: C21H30N8O3. Mole weight: 442.52.
LY 206130
This active molecular is a serotonin 5-HT1A antagonist. LY 206130 (3.0 mg/kg, s.c.) alone significantly increased norepinephrine level by 60%, dopamine levels by 34% without affecting 5-HT levels. Synonyms: LY 206130; LY-206130; LY206130. CHEMBL396185;AC1L3YFA; SCHEMBL7287084;1-(cyclohexylamino)-3-(1H-indol-4-yloxy)propan-2-ol. Grades: 98%. CAS No. 127414-58-8. Molecular formula: C17H24N2O2. Mole weight: 288.39.
LY-207702
LY-207702 is a difluorinated purine nucleoside. It exhibits antitumor activity in preclinical models. It was developed by Eli Lilly & Co. Uses: Ly-207702 exhibits antitumor activity. Synonyms: LY 207702; LY-207702; LY207702. 2',2'-Difluorodeoxyribofuranosyl-2,6-diaminopurine;5-(2,6-diamino-7H-purin-8-yl)-4,4-difluoro-2-(hydroxymethyl)oxolan-3-ol;9-(2-Deoxy-2,2-difluoro-D-erythro-pentofuranosyl)-9H-purine-2,6-diamine;(2R,3R)-5-(2,6-diamino-7H-purin-8-yl)-4,4-difluoro-2-(hydroxymethyl)oxolan-3-ol;9H-Purine-2,6-diamine, 9-(2-deoxy-2,2-difluoro-D-erythro-pentofuranosyl)-. Grades: >98 %. CAS No. 103828-81-5. Molecular formula: C10H12F2N6O3. Mole weight: 302.24.
LY2090314 is a potent GSK3 inhibitor with antiproliferative activity. It was shown to promote differentiation of intestinal progenitor cells from human iPSCs. Synonyms: LY-2090314; 3-[6-fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-3-yl]-4-imidazo[1,2-a]pyridin-3-ylpyrrole-2,5-dione. Grades: >98%. CAS No. 603288-22-8. Molecular formula: C28H25FN6O3. Mole weight: 512.545.
LY2090314
LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50 values of 1.5 nM and 0.9 nM for GSK-3? and GSK-3?, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 603288-22-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16294.
LY 210073
LY 210073, an oxoxanthene derivative, has been found to be a LTB4 receptor antagonist that could probably be effective against inflammation and rheumatic disorders. Synonyms: 9H-Xanthene-4-propanoicacid, 7-carboxy-3-[[(5E)-6-(4-methoxyphenyl)-5-hexen-1-yl]oxy]-9-oxo-; ACMC-20n5ed; CTK0H7653; CTK8H0111; LY 210073; LY-210073; LY210073. Grades: 98%. CAS No. 148291-65-0. Molecular formula: C30H28O8. Mole weight: 516.55.
LY2109761
LY2109761 is a novel inhibitor of TGF-β receptor type I/type II kinases (IC50 = 69 nM), displaying antitumor activity. In vivo study demonstrated that LY2109761, in combination with gemcitabine, significantly reduced the tumor burden, prolonged survival, and reduced spontaneous abdominal metastases. Synonyms: LY-2109761; 4-(2-((4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethyl)morpholine. Grades: >98%. CAS No. 700874-71-1. Molecular formula: C26H27N5O2. Mole weight: 441.52.
LY2109761
LY2109761 is an orally active, selective TGF-? receptor type I/II inhibitor with Kis of 38 nM and 300 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 700874-71-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12075.
LY 2109761
LY 2109761. Group: Biochemicals. Alternative Names: 4-[5,6-Dihydro-2-(2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-morpholinyl)ethoxy]-quinoline. Grades: Highly Purified. CAS No. 700874-71-1. Pack Sizes: 5mg. Molecular Formula: C26H27N5O2, Molecular Weight: 441.52. US Biological Life Sciences.
Worldwide
LY2119620
LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors. Synonyms: LY2119620; LY 2119620; LY-2119620. Grades: >98%. CAS No. 886047-22-9. Molecular formula: C19H24ClN5O3S. Mole weight: 437.94.
LY 213024
LY 213024 is a potent leukotriene B4 receptor antagonist. Agents which block the production of the leukotrienes have shown reduction of infarct size in animal models of myocardial infarction. Uses: Myocardial infarction. Synonyms: LY 213024; LY213024; LY-213024; 3-[3-(2-carboxyethyl)-4-decoxybenzoyl]benzoic acid. Grades: 98%. CAS No. 117423-95-7. Molecular formula: C27H34O6. Mole weight: 454.56.
LY2140023
LY2140023 is a prodrug of LY-404039 and a novel metabotropic glutamate 2/3 receptor agonist peptide prodrug. lt is currently in clinical development as a potential new treatment for schizophrenia. Uses: Ly2140023 was used for the treatment of post-traumatic stress disorder and for the treatment of schizophrenia. Synonyms: Pomaglumetad methionil; LY-2140023; LY 2140023. Grades: 98%. CAS No. 635318-55-7. Molecular formula: C12H18N2O7S2. Mole weight: 366.40.
LY2157299 (LY 2157299, LY-2157299, Galunisertib)
LY2157299 (LY 2157299, LY-2157299, Galunisertib). Group: Biochemicals. Alternative Names: 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide. Grades: Highly Purified. CAS No. 700874-72-2. Pack Sizes: 5mg, 50mg. Molecular Formula: C22 H19 N5 , Molecular Weight: 369.4. US Biological Life Sciences.
Worldwide
LY 215840
LY 215840. Group: Biochemicals. Grades: Purified. CAS No. 137328-52-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
LY 215840
LY 215840 is a potent antagonist of both Serotonin 2A receptor and Serotonin 7 receptor. It can reduce stimulatory effect of serotonin on aldosterone secretion and 5-HT-induced cAMP formation. LY 215840 has anti-hypertensive and muscle relaxant effects in animal models. No development was reported for the treatment of Thrombosis and Migraine. Uses: Migraine; thrombosis. Synonyms: LY 215840; LY-215840; LY215840. (6aR,9R)-N-[(1S,2R)-2-hydroxycyclopentyl]-7-methyl-4-propan-2-yl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-carboxamide. Grades: >98 %. CAS No. 137328-52-0. Molecular formula: C24H33N3O2. Mole weight: 395.55.
LY 215890
LY 215890 has been found to have probable antibiotic activity. Synonyms: LY 215890; LY-215890; LY215890. 7-(((2-Amino-4-thiazolyl)hydroximinoacetyl)amino)-3-chloro-1-carba-1-dethia-3-cephem-4-carboxylic acid. Grades: 98%. CAS No. 153502-35-3. Molecular formula: C13H12ClN5O5S. Mole weight: 385.78.
LY2183240 is a novel and highly potent blocker of anandamide uptake. It inhibits fatty acid amide hydrolase (FAAH) activity. It increases brain anandamide concentration and exerts antinociceptive effects in formalin model of pain. Synonyms: LY2183240; LY-2183240; LY 2183240. Grades: >98%. CAS No. 874902-19-9. Molecular formula: C17H17N5O. Mole weight: 307.35.
LY2183240 2'-isomer
LY2183240 2'-isomer is a 2,5-regioisomer of LY2183240 that inhibits anandamide hydrolysis and cellular reuptake. LY2183240 2'-isomer exhibits less potent activity than LY2183240. Synonyms: 5-([1,1'-Biphenyl]-4-ylmethyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide; 5-((biphenyl-4-yl)methyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide. Grades: ≥98%. CAS No. 1010096-65-7. Molecular formula: C17H17N5O. Mole weight: 307.4.
LY 219057
LY 219057, a phenylpyrazolidine derivative, has been found to be a CCK receptor antagonist that could probably be useful in gastrointestinal disorder studies. Synonyms: LY 219057; LY-219057; CHEMBL353189; N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxo-4,5-diphenylpyrazolidine-1-carbothioamide. Grades: 98%. CAS No. 150351-93-2. Molecular formula: C23H17ClF3N3OS. Mole weight: 475.91.
LY 221068
LY 221068 is a Lipoxygenase inhibitor originated by Eli Lilly. It is a potent antioxidant with antiinflammatory properties. But no development was reported for Rheumatic disorders in USA. Uses: Rheumatic disorders. Synonyms: LY 221068; LY-221068; LY221068; 5-((3,5-Bis(1,1,-dimethylethyl)-4-hydroxyphenyl)methylene)-3-(dimethylamino)-4-thiazolidinone. Grades: 98%. CAS No. 132392-39-3. Molecular formula: C20H30N2O2S. Mole weight: 362.54.
LY-221501
LY-221501, a piperidine derivative, has been found to be a NMDA receptor antagonist. Synonyms: LY 221501; LY221501; LY-221501; Cis-4-(3-Carboxyprop-1-yl)piperidine-2-carboxylic acid; 145512-35-2; LY 221501; 4-Piperidinebutanoicacid, 2-carboxy-, (2R,4S)-; AC1L31HC. Grades: 98%. CAS No. 145512-35-2. Molecular formula: C10H17NO4. Mole weight: 215.25.
LY2228820
LY2228820. Group: Biochemicals. Alternative Names: 5-[2-(1,1-Dimethylethyl)-5-(4-fluorophenyl)-1H-imidazol-4-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin-2-amine dimethanesulfonate. Grades: Highly Purified. CAS No. 862507-23-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H37FN6O6S2. US Biological Life Sciences.
Worldwide
LY2228820
LY2228820 is a novel and potent p38MAPK inhibitor (the IC50 for p38αMAPK and p38βMAPK were 7 nM and 3 nM, respectively). Synonyms: Ralimetinib; LY2228820; LY 2228820; LY-2228820. Grades: >98%. CAS No. 862505-00-8. Molecular formula: C24H29FN6. Mole weight: 420.53.
LY2228820 dimesylate
LY2228820 dimesylate is the salt form of LY2228820, a tri-substituted imidazole derivative and p38α and β MAPK inhibitor. LY2228820 inhibits tumor growth in various cancer models. Synonyms: Ralimetinib Mesylate; Ralimetinib dimesylate; 5-[2-tert-butyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)imidazo[4,5-b]pyridin-2-amine mesylate. Grades: >98%. CAS No. 862507-23-1. Molecular formula: C26H37FN6O6S2. Mole weight: 612.74.
LY-223592
LY-223592 is a bio-active chemical compound. It has antitumor activity. It was developed by Eli Lilly & Co. Uses: Ly-223592 has antitumor activity. Synonyms: LY 223592; LY223592; LY-223592. 2'-Deoxy-2',2'-difluoro-guanosine;Guanosine, 2'-deoxy-2',2'-difluoro-;2-Amino-9-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one;LY223592;2',2'-Difluorodeoxyguanosine. Grades: >98 %. CAS No. 103828-82-6. Molecular formula: C10H11F2N5O4. Mole weight: 303.22.
LY223982
This active molecular is benzophenone dicarboxylic acid derivative which is a potent BLT1 receptor antagonist. It inhibits the binding of radiolabeled-LTB4 to isolated human neutrophils and IC50 value is 13.2 nM. LY223982 also inhibits the leukotriene B4 (LTB4)-induced aggregation of guinea human neutrophils. IC50 value is 100 nM. In Aug 1997, phase II for Psoriasis in USA was discontinued. Uses: Psoriasis. Synonyms: LY 223982; LY-223982; LY223982; CGS 23131; SKF 107324; CGS23131; SKF107324; CGS-23131; SKF-107324; 5-(3-Carboxybenzoyl)-2-((6-(4-methoxyphenyl)-5-hexenyl)oxy)benzenepropanoic acid. Grades: 98%. CAS No. 117423-74-2. Molecular formula: C30H30O7. Mole weight: 502.56.
LY 225910 is a CCK2 receptor antagonist with IC50 value of 9.3 nM. Synonyms: LY 225910; LY-225910; LY225910; 2-[2-(5-Bromo-1H-indol-3-yl)ethyl]-3-[3-(1-methylethoxy)phenyl]-4-(3H)-quinazoline. Grades: ≥95%. CAS No. 133040-77-4. Molecular formula: C27H24BrN3O2. Mole weight: 502.41.
LY 225910
LY 225910 is a selective antagonist for cholecystokinin receptor ( CCK2 receptor ), which affects the excitatory response to morphine, and leads to morphine sensitization [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133040-77-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101352.
LY 231617
LY 231617 is an antioxidant. It can prevent ischaemia-induced neurodegeneration. LY 231617 is an anti-ischaemic and neuroprotective agent. Synonyms: LY 231617; LY231617; LY-231617; 2,6-bis(1,1-Dimethylethyl)-4-[(ethylamino)methyl]phenol hydrochloride. Grades: ≥98% by HPLC. CAS No. 141545-89-3. Molecular formula: C17H29NO.HCl. Mole weight: 299.88.
LY 231617
LY 231617. Group: Biochemicals. Grades: Purified. CAS No. 141545-89-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
LY 233053
LY 233053 is an NMDA receptor antagonist with IC50 value of 7 nM. Synonyms: LY233053; LY-233053 LY 233053; (2R*,4S*)-4-(1H-Tetrazol-5-ylmethyl)-2-piperidinecarboxylic acid. Grades: ≥99% by HPLC. CAS No. 125546-04-5. Molecular formula: C8H13N5O2. Mole weight: 211.22.
LY2334737
LY2334737 is an orally available valproic acid ester of gemcitabine, which is a broad-spectrum antimetabolite with antineoplastic activity. It is an orally available prodrug of gemcitabine which is a nucleoside analog used as chemotherapy. It is hydrolyzed by carboxylesterase 2 (CES2) and releases gemcitabine systemically over a period of time consistent with formation rate-limited kinetics. It was less cytotoxic to a SK-OV-3 CES2 knockdown than parental cells. Uses: Ly2334737 is used as chemotherapy. it has antineoplastic activity. Synonyms: LY2334737; LY 2334737; LY-2334737; gemcitabine prodrug; 2'-Deoxy-2',2'-difluoro-N-(1-oxo-2-propylpentyl)cytidine;N-[1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]-2-propylpentanamide. Grades: >98 %. CAS No. 892128-60-8. Molecular formula: C17H25F2N3O5. Mole weight: 389.39.
LY 233536
LY 233536 is a novel competitive N-methyl-D-aspartate (NMDA) receptor antagonist, but few detailed information has been published yet. Synonyms: LY 233536; LY-233536; LY233536; (3R-(3alpha,4aalpha,6beta,8aalpha))-decahydro-6-(1H-tetrazol-5-ylmethyl)- 3-Isoquinolinecarboxylic acid. Grades: 98%. CAS No. 136845-59-5. Molecular formula: C12H19N5O2. Mole weight: 265.32.
LY 235959
LY 235959 is a competitive N-Methyl-D-Aspartate Receptor antagonist originated by Eli Lilly. No development was reported for treatment of Movement disorders in USA. Research for treatment of Alzheimer's disease was discontinued. Uses: Alzheimer's disease;movement disorders. Synonyms: LY 235959; LY235959; LY-235959; (3S)-(3-alpha-4-alpha,alpha-6-beta-8-alpha,alpha)-Decahydro-6-(phosphonomethyl)-3-isoquinolinecarboxylic acid;LY 235959. Grades: 98%. CAS No. 137433-06-8. Molecular formula: C11H20NO5P. Mole weight: 277.26.
LY 2365109 hydrochloride
Cas No. 868265-28-5.
LY 2365109 hydrochloride
LY 2365109 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 868265-28-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
LY 2389575 hydrochloride
LY 2389575 hydrochloride is a mGluR3 receptor antagonist with IC50 value of 190 nM. Synonyms: LY2389575; LY-2389575; LY 2389575; (3S)-N-(2,4-Dichlorobenzyl)-1-(5-bromopyrimidin-2-yl)pyrrolidinyl-3-amine hydrochloride. Grades: ≥98% by HPLC. CAS No. 885104-09-6. Molecular formula: C15H15BrCl2N4.HCl. Mole weight: 438.58.
LY 2389575 hydrochloride
LY 2389575 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 885104-09-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
LY2409881
LY2409881 is a novel selective inhibitor of IKK2. It inhibited constitutively activated NF-κB, and caused concentration- and time-dependent growth inhibition and apoptosis in lymphoma cells. It suppressed the activity of the NF-κB subunit p65 in lymphoma cells treated by the HDAC inhibitor romidepsin, underlying a potential mechanism of the marked synergy observed of these two drugs. Synonyms: LY2409881; LY 2409881; LY-2409881. Grades: >98%. CAS No. 946518-61-2. Molecular formula: C24H29ClN6OS. Mole weight: 485.04.
LY2409881 Trihydrochloride
LY2409881 is a potent and selective IKK2 inhibitor with IC50 of 30 nM, >10-fold selectivity over IKK1 and other common kinases. Synonyms: LY2409881; LY 2409881; LY-2409881. Grades: >98%. CAS No. 946518-60-1. Molecular formula: C24H32Cl4N6OS. Mole weight: 594.43.
LY 243670
LY 243670 is a bio-active molecular, but detailed information were not published yet. Synonyms: LY 243670; LY-243670; LY243670. 1-(3-Hydroxy-3-cyclohexylpropyl)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidine. Grades: 98%. CAS No. 120938-72-9. Molecular formula: C22-H35-N-O2. Mole weight: 345.52.
LY2452473
LY2452473 is an orally bioavailable, selective androgen receptor modulator (SARM). Uses: Scientific research. Group: Signaling pathways. CAS No. 1029692-15-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114530.
LY-2456302
LY-2456302, also called as CERC-501, is a potent, highly selective and centrally-penetrant kappa opioid receptor antagonist (Ki = 0.807 nM) with favorable pharmacokinetic and pharmacodynamic properties to evaluate the role of KOR in preclinical models of alcoholism. Synonyms: 4-[4-[[(2S)-2-(3,5-dimethylphenyl)pyrrolidin-1-yl]methyl]phenoxy]-3-fluorobenzamide; 3-fluoro4-(4-((2-(3,5-dimethylphenyl)pyrrolidin-1-yl)methyl)phenoxy)benzamide; LY2456302; CERC-501; LY 2456302; CERC 501; LY-2456302; CERC501. CAS No. 1174130-61-0. Molecular formula: C26H27FN2O2. Mole weight: 418.5.
LY2457546
LY2457546 is a potent and orally bioavailable inhibitor of multiple receptor tyrosine kinases involved in angiogenic and tumorigenic signalling. Synonyms: LY 2457546; LY-2457546. CAS No. 908265-94-1. Molecular formula: C28H20F4N4O. Mole weight: 504.48.
LY 245769
LY 245769 is a leukotriene E4 (LTE4) inhibitor, and it can inhibit the oxidative degradation of LTE4 and N-acetyl-LTE4 in animal model. LY 245769, as one of the omega-trifluoro analogs of leukotrienes, will provide a new tool for interfering with the inactivation of leukotrienes in the omega-oxidation pathway. Synonyms: LY 245769; LY-245769; LY245769; R-(R*,S*-(E,Z)))-3-(1H-tetrazol-5-yl)-alpha-(14,14,14-trifluoro-1-((2-(1H-tetrazol-5-yl)ethyl)thio)-2,4-tetradecadienyl)-3-(1H-tetrazol-5-yl)-alpha-(14,14,14-trifluoro-1-((2-(1H-tetrazol-5-yl)ethyl)thio)-2,4-tetradecadienyl)-. Grades: 98%. CAS No. 127345-02-2. Molecular formula: C25H33F3N8OS. Mole weight: 550.65.
LY 249933
LY 249933 is a bio-active molecular under the development of Eli Lilly. It has positive inotropic activity as a cardioselective 1,4-dihydropyridine compound. Uses: Positive inotropic activity. Synonyms: LY 249933; LY249933; LY-249933. 1-phenylethyl 2,6-dimethyl-5-nitro-4-thieno[3,2-c]pyridin-3-yl-1,4-dihydropyridine-3-carboxylate. Grades: 98%. CAS No. 123250-77-1. Molecular formula: C23H21N3O4S. Mole weight: 435.50.
LY2510924
LY2510924 is a potent and selective CXCR4 antagonist that blocks SDF-1 binding to CXCR4 with an IC50 of 0.079 nM. Uses: Scientific research. Group: Peptides. CAS No. 1088715-84-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12488.
LY-2510924
LY-2510924 is an inhibitor of CXC chemokine receptor 4 (CXCR4). It has potential antineoplastic activity. It binds to the chemokine receptor CXCR4, thereby preventing CXCR4 binding to its ligand, stromal derived factor-1 (SDF-1), and subsequent receptor activation upon subcutaneous administration, which may result in decreased tumor cell proliferation and migration. It plays an important role in chemotaxis and angiogenesis and is upregulated in several tumor cell types. Uses: Ly-2510924 has potential antineoplastic activity. it plays an important role in chemotaxis and angiogenesis. Synonyms: LY2510924; LY 2510924; Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2; Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2; L-Lysinamide, L-phenylalanyl-L-tyrosyl-N6-(1-methylethyl)-L-lysyl-D-arginyl-3-(2-naphthalenyl)-L-alanylglycyl-D-α-glutamyl-N6-(1-methylethyl)-, (7?1)-lactam; N(1)Phe-Tyr-Lys(iPr)-D-Arg-2Nal-Gly-D-Glu(1)-Lys(iPr)-NH2. Grades: 98%. CAS No. 1088715-84-7. Molecular formula: C62H88N14O10. Mole weight: 1189.47.
LY2510924 acetate
Ly2510924 acetate is a potent and selective CXCR4 antagonist that prevents the binding of SDF-1 to CXCR4 with an IC50 of 0.079 nM. It has potential antineoplastic activity. Synonyms: L-Lysinamide, L-phenylalanyl-L-tyrosyl-N6-(1-methylethyl)-L-lysyl-D-arginyl-3-(2-naphthalenyl)-L-alanylglycyl-D-α-glutamyl-N6-(1-methylethyl)-, (7?1)-lactam, acetate (1:1); LY 2510924 acetate; LY-2510924 acetate; N(1)Phe-Tyr-Lys(iPr)-D-Arg-2Nal-Gly-D-Glu(1)-Lys(iPr)-NH2 acetate. Grades: ≥95%. Molecular formula: C62H88N14O10.C2H4O2. Mole weight: 1249.53.
LY 255262
This bio-active molecular is a antibacterial agent with a pyrazolidinone structure. Uses: Antibacterial. Synonyms: LY 255262; LY255262; LY-255262. 2-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-6-cyano-3-oxo-2,7-dihydro-1H-pyrazolo[1,2-a]pyrazole-5-carboxylic acid. Grades: 98%. CAS No. 124986-45-4. Molecular formula: C14H13N7O5S. Mole weight: 391.36.
LY255283
This active molecular is a competitive leukotriene B4 receptor antagonist and IC50 value is about 100 nM. LY 255283 is selective for the BLT2 receptor, since IC50 values at the BLT1 receptor are >10 μM. LY255283 inhibits eosinophil chemotaxis by 80% at a concentration of 10 μM. It also inhibits the binding of radiolabeled LTB4 to eosinophil membranes and IC50 value is 260 nM. LY255283 reduces airway obstruction in animal models of asthma. However, clinical trials for asthma had been discontinued. Uses: Asthma. Synonyms: LY 255283; LY255283; LY-255283; (1-(5-Ethyl-2-hydroxy-4-(6-methyl-6-(1H-tetrazol-5-yl)heptyloxy)phenyl)ethanone). Grades: 98%. CAS No. 117690-79-6. Molecular formula: C19H28N4O3. Mole weight: 360.45.