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| Product | Description | |
|---|---|---|
| Mitofusin 2 Antibody [J12N7] | MFN2,Mfn2 / Mitofusin 2,Mitofusin 2,Mitofusin-2. Group: Antibodies. Alternative Names: MFN2,Mitofusin-2. Pack Sizes: 20uL. Product ID: F0566. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| mitogen-activated protein kinase | Phosphorylation of specific tyrosineand threonine residues in the activation loop of this enzyme by EC 2.7.12.2, mitogen-activated protein kinase kinase (MAPKK) is necessary for enzyme activation. Once activated, the enzyme phosphorylates target substrates on serine or threonine residues followed by a proline. A distinguishing feature of all MAPKs is the conserved sequence Thr-Xaa-Tyr (TXY). Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e.g. insulin and growth hormone), mitogens (e.g. epidermal growth.pk; PMK-1; PMK-2; PMK-3; pp42; pp44mapk; p44mpk; SAPK; STK26; stress-activated protein kinase. Enzyme Commission Number: EC 2.7.11.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3144; mitogen-activated protein kinase; EC 2.7.11.24; c-Jun N-terminal kinase; Dp38; ERK; ERK1; ERK2; extracellular signal-regulated kinase; JNK; JNK3α1; LeMPK3; MAP kinase; MAP-2 kinase; MAPK; MBP kinase I; MBP kinase II; microtubule-associated protein 2 kinase; microtubule-associated protein kinase; myelin basic protein kinase; p38Δ; p38-2; p42 mitogen-activated protein kinase; p42mapk; PMK-1; PMK-. |  |
| Mitogen activated protein kinase from rat, Recombinant | Mitogen-activated protein kinases (MAPK) are protein kinases that are specific to the amino acids serine, threonine, and tyrosine. MAPKs belong to the CMGC (CDK/MAPK/GSK3/CLK) kinase group. MAPKs are involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. They regulate cell functions including proliferation, gene expression, differentiation, mitosis, cell survival, and apoptosis. > 95% (sds-page), buffered aqueous glycerol solution, recombinant, expressed in e. coli (n-terminal histidine tagged). Group: Enzymes. Synonyms: ERK2; Extracellular-signal regulated kinase; MAP Kinase Activated from rat; MAPK; Mitogen activated protein kinase. Purity: > 95% (SDS-PAGE). MAP kinase. Mole weight: mol wt 42 kDa. Activity: > 500 U/mg. Stability: -70°C. Form: buffered aqueous glycerol solution. Source: E. coli. Species: Rat. ERK2; Extracellular-signal regulated kinase; MAP Kinase Activated from rat; MAPK; Mitogen activated protein kinase. Pack: vial of 100 ng. Cat No: NATE-0443. | |
| mitogen-activated protein kinase kinase | This enzyme is a dual-specific protein kinase and requires mitogen-activated protein kinase kinase kinase (MAPKKK) for activation. It is required for activation of EC 2.7.11.24, mitogen-activated protein kinase. Phosphorylation of MEK1 by Raf involves phosphorylation of two serine residues. Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e.g. insulin and growth hormone), mitogens (e.g. epidermal growth factor and platelet-derived growth factor), vasoactive peptides (e.g. angiotensin-II and endothelin), inflammatory cytokines of the tumour necrosis factor (TNF) family and environmental stresses such as osmotic shock, ionizing radiation and ischaemic injury. Group: Enzymes. Synonyms: MAP kinase kinase; MAP kinase kinase 4; MAP kinase kinase 7; MAP kinase or ERK. Enzyme Commission Number: EC 2.7.12.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3162; mitogen-activated protein kinase kinase; EC 2.7.12.2; MAP kinase kinase; MAP kinase kinase 4; MAP kinase kinase 7; MAP kinase or ERK kinase; MAP2K; MAPKK; MAPKK1; MEK; MEK1; MEK2; MKK; MKK2; MKK4; MKK6; MKK7; STK27. Cat No: EXWM-3162. | |
| mitogen-activated protein kinase kinase kinase | This enzyme phosphorylates and activates its downstream protein kinase, EC 2.7.12.2, mitogen-activated protein kinase kinase (MAPKK) but requires MAPKKKK for activation. Some members of this family can be activated by p21-activated kinases (PAK/STE20) or Ras. While c-Raf and c-Mos activate the classical MAPK/ERK pathway, MEKK1 and MEKK2 preferentially activate the c-Jun N-terminal protein kinase(JNK)/stress-activated protein kinase (SAPK) pathway. Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e.mes. Synonyms: cMos; cRaf; MAPKKK; MAP3K; MAP kinase kinase kinase; MEKK; MEKK1; MEKK2; MEKK3; MEK kinase; Mil/Raf; MLK-like mitogen-activated protein triple kinase; MLTK; MLTKa; MLTKb; REKS; STK28. Enzyme Commission Number: EC 2.7.11.25. CAS No. 146702-84-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3145; mitogen-activated protein kinase kinase kinase; EC 2.7.11.25; 146702-84-3; cMos; cRaf; MAPKKK; MAP3K; MAP kinase kinase kinase; MEKK; MEKK1; MEKK2; MEKK3; MEK kinase; Mil/Raf; MLK-like mitogen-activated protein triple kinase; MLTK; MLTKa; MLTKb; REKS; STK28. Cat No: EXWM-3145. | |
| Mitogenic Pentapeptide | Mitogenic Pentapeptide represents a potent activator for monocytes / macrophages and B lymphocytes. Alternative Names: Tripalmitoyl pentapeptide; Bppp-cssaa; P3C-Ssna; Pam3Cys-ser-ser-asn-ala; 2,3-Bis(palmitoyloxy)propyl-N-palmitoylpentapeptide. CAS No. 87173-03-3. Molecular formula: C67H124N6O14S. Mole weight: 1269.80. |  |
| Mitoglitazone | Mitoglitazone. Uses: For analytical and research use. CAS No. 146062-49-9. Mole weight: 370.42. Catalog: AP146062499. |  |
| Mitoguazone | Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Methylglyoxal-bis(guanylhydrazone); MGBG; Methyl-GAG. CAS No. 459-86-9. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106634. |  |
| Mitoguazone dihydrochloride monohydrate | Mitoguazone dihydrochloride monohydrate (CAS# 332360-02-8 ) is a useful research chemical. Alternative Names: Methylglyoxal bis(guanylhydrazone) hydrate dihydrochloride; 2,2'-(1-Methyl-1,2-ethanediylidene) bis(hydrazinecarboximidamide) dihydrochloride hydrate; Methylglyoxal bis(guanylhydrazone) dihydrochloride hydrate; Methyl GAG dihydrochloride monohydrate; Methylglyoxal bis(guanylhydrazone) dihydrochloride monohydrate; 2,2'-(Propane-1,2-diylidene)di(hydrazine-1-carboximidamide)-hydrogen chloride-water. CAS No. 332360-02-8. Molecular formula: C5H16Cl2N8O. Mole weight: 275.14. | |
| MitoHunt Red CM-H2Xros | MitoHunt Red CM-H2XRos is a nonfluorescent form of MitoHunt Red that fluoresces upon oxidation. Alternative Names: 16-[4-(chloromethyl)phenyl]-3-oxa-9,23-diazaheptacyclo[17.7.1.15,9.02,17.04,15.023,27.013,28]; octacosa-1(27),2(17),4(15),5(28),13,18-hexaene; 1H,5H,9H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizine,9-[4-(chloromethyl)phenyl]-2,3,6,7,12,13,16,17-octahydro-; 9-[4-(Chloromethyl)phenyl]-2,3,6,7,12,13,16,17-octahydro-1H,5H,9H,11H,15H-xantheno[2,3,4-ij:5,6,7-i'j inverted exclamation marka]diquinolizine. CAS No. 167095-08-1. Molecular formula: C32H33ClN2O. Mole weight: 497.08. | |
| Mito-LND | Mito-LND (Mito-Lonidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation (OXPHOS). Mito-LND inhibits mitochondrial bioenergetics, stimulates the formation of reactive oxygen species, and induces autophagic cell death in lung cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mito-Lonidamine. CAS No. 2361564-49-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134832. | |
| mitomycin 6-O-methyltransferase | The enzyme, characterized from the bacterium Streptomyces lavendulae, is involved in the biosynthesis of the quinone-containing antibiotics mitomycin A and mitomycin B. Group: Enzymes. Synonyms: MmcR; mitomycin 7-O-methyltransferase (incorrect); S-adenosyl-L-methionine:7-demethylmitomycin-A 7-O-methyltransferase (incorrect). Enzyme Commission Number: EC 2.1.1.316. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1924; mitomycin 6-O-methyltransferase; EC 2.1.1.316; MmcR; mitomycin 7-O-methyltransferase (incorrect); S-adenosyl-L-methionine:7-demethylmitomycin-A 7-O-methyltransferase (incorrect). Cat No: EXWM-1924. | |
| Mitomycin A | Mitomycin A is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. It has an inhibitory effect on tumors. Alternative Names: Mitomycin EP Impurity B; Mitiromycin B. Grades: > 95%. CAS No. 4055-39-4. Molecular formula: C16H19N3O6. Mole weight: 349.34. | |
| Mitomycin B | Mitomycin B is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. It has an inhibitory effect on tumors. Alternative Names: Mitomycin EP Impurity C; (1aS)-8α-[[(Aminocarbonyl)oxy]methyl]-1,1aα,2,8,8aα,8bα-hexahydro-1,5-dimethyl-8a-hydroxy-6-methoxyazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione;[1aS-(1aalpha,8alpha,8aalpha,8balpha)]-8-[[(Aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-6-methoxy-1,5-dimethyl-azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione. Grades: > 95%. CAS No. 4055-40-7. Molecular formula: C16H19N3O6. Mole weight: 349.34. | |
| Mitomycin C | 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H18N4O5. CAS No. 50-07-7. Prepack ID 17545348-25mg. Molecular Weight 334.33. See USA prepack pricing. |  |
| Mitomycin C | Mitomycin C (Ametycine) is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers. Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95-independent manner.This product is a hazardous chemical (acute toxicity / flammable / skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing. Group: Inhibitors. Alternative Names: Ametycine. CAS No. 50-07-7. Pack Sizes: 10mg. Product ID: S8146. Formula: C15H18N4O5. Smiles: CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Mitomycin C | Mitomycin C is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. And it has an inhibitory effect on tumors. Uses: Mitomycin c is also available as a a 4% mixture in nacl. see "mitomycin c+nacl" sample coa. Alternative Names: Mitiromycin E; Mutamycin; Ametycine; Zilimeisu. Grades: Assay ≥ 970 mg/g Mitomycin. CAS No. 50-07-7. Molecular formula: C15H18N4O5. Mole weight: 334.33. | |
| Mitomycin C | 2mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H18N4O5. CAS No. 50-07-7. Prepack ID 17545348-2mg. Molecular Weight 334.33. See USA prepack pricing. | |
| Mitomycin C | An antitumor antibiotic. It is used as antineoplastic. Group: Biochemicals. Alternative Names: [1aS-(1aα,8 β , 8aα , 8bα ) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, 3: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; MMC; Ametycine; Mutamycin; Mitonco; Mitoplus. Grades: Highly Purified. CAS No. 50-07-7. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Mitomycin C Pure (NaCl-Free) | Supplied as a pure preparation of Mitomycin C. This preparation contains no sodium chloride. Group: Biochemicals. Alternative Names: Streptomyces caespitosus; Ametycine; MMC; Mutamycin; [1aS- (1aa, 8b, 8aa, 8ba) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, 3: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Molecular Biology Grade. CAS No. 50-07-7. Pack Sizes: 4mg, 12mg, 24mg, 40mg. US Biological Life Sciences. | Worldwide |
| Mitomycin C w/NaCl | Supplied as a preparation of Mitomycin C with sodium chloride in a ratio of 2mg Mitomycin C and 48mg sodium chloride. Group: Biochemicals. Alternative Names: Streptomyces caespitosus; Ametycine; MMC; Mutamycin; [1aS- (1aa, 8b, 8aa, 8ba) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, 3: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Molecular Biology Grade. CAS No. 50-07-7. Pack Sizes: 2mg. US Biological Life Sciences. | Worldwide |
| Mitomycin D | Mitomycin D. Group: Biochemicals. Alternative Names: (1aS, 8R, 8aR, 8bS) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-hydroxy-1, 5-dimethylazirino[2', 3': 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Highly Purified. CAS No. 10169-34-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C15H18N4O5. US Biological Life Sciences. | Worldwide |
| Mitomycin D | Mitomycin D is a mito-mycin antibiotic produced by Streptomyces caespitosus with anti-tumor activity. It is also a semi-synthetic antibiotic with anti-leukemic properties. Uses: An antitumor antibiotic. it is used as antineoplastic. Alternative Names: 7-Demethoxy-7-aminomitomycin B; (1aS,8R,8aR,8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-1,5-dimethylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione; [(1aS,8S,8aR,8bS)-6-Amino-8a-hydroxy-1,5-dimethyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methylcarbamate; Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-6-amino-8-(((aminocarbonyl)oxy)methyl)-1,5-dimethyl-8a-hydroxy-, (1aS-(1a-α,8-β,8a-α,8b-α))-; BRN 4720574; NSC 123106. Grades: 95%. CAS No. 10169-34-3. Molecular formula: C15H18N4O5. Mole weight: 334.33. | |
| Mitomycin EP Impurity A | Mitomycin EP Impurity A. Uses: For analytical and research use. CAS No. 621-79-4. Molecular formula: C9H9NO. Mole weight: 147.17. Catalog: APB621794. | |
| Mitomycin EP Impurity B | Mitomycin EP Impurity B. Uses: For analytical and research use. CAS No. 4055-39-4. Molecular formula: C16H19N3O6. Mole weight: 349.34. Catalog: APB4055394. | |
| Mitomycin EP Impurity C | Mitomycin EP Impurity C. Uses: For analytical and research use. CAS No. 4055-40-7. Molecular formula: C16H19N3O6. Mole weight: 349.34. Catalog: APB4055407. | |
| Mitomycin EP Impurity D | Mitomycin EP Impurity D. Uses: For analytical and research use. CAS No. 111750-67-5. Molecular formula: C15H18N4O5. Mole weight: 334.33. Catalog: APB111750675. | |
| Mitonafide | A Naphthalimides with potent anticancer activity. Group: Biochemicals. Alternative Names: 2-[2-(Dimethylamino)ethyl]-5-nitro-1H-benz[de]isoquinoline-1,3(2H)-dione. Grades: Highly Purified. CAS No. 54824-17-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Mitonafide | Mitonafide (NSC 300288) is a cytostatic agent. Mitonafide binds to double-stranded DNA through intercalation, and inhibits DNA and RNA synthesis. Mitonafide is an antitumor agent that can be used in the research of cancers, such as non-small cell lung cancer (NSCLC), leukemia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 300288. CAS No. 54824-17-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119182. | |
| MitoPerOx | MitoPerOx is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state), and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1392820-50-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-125623. | |
| MitoPerOx | MitoPerOx is a fluorescent probe that can be used for measuring changes in lipid peroxidation within mitochondria. It is composed of a BODIPY fluorophore conjugated via a dienyl link to a triphenylphosphonium cation component that drives its accumulation in mitochondria. Alternative Names: (2-(3-(5,5-difluoro-7-((1E,3E)-4-phenylbuta-1,3-dien-1-yl)-5H-5λ4,6λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)propanamido)ethyl)triphenylphosphonium, monobromide. Grades: ≥95%. CAS No. 1392820-50-6. Molecular formula: C42H38BF2BrN3OP. Mole weight: 760.46. | |
| MitoPQ | MitoPQ is a mitochondria-targeted redox cycler. MitoPQ produces superoxide by redox cycling at the flavin site of complex I, selectively increasing superoxide production within mitochondria. MitoPQ can be used in antioxidant study[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MitoParaquat. CAS No. 1821370-28-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130278. | |
| MitoPY1 | MitoPY1 is a targetable fluorescent probe for imaging hydrogen peroxide (H2O2) in mitochondria of living cells, which displays enhanced emission at 528 nm in the presence of H2O2. Alternative Names: [4-[4-[3-Oxo-6'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl]-1-piperazinyl]butyl]triphenyl-phosphonium iodide. CAS No. 1041634-69-8. Molecular formula: C52H53BIN2O5P. Mole weight: 954.68. | |
| MitoQ (Mitoquinone) Mesylate | MitoQ (Mitoquinone) mesylate is a TPP-based, mitochondria-targeted antioxidant that blocks H2O2-induced intracellular ROS responses and protects against oxidative damage. This product is a waxy solid. Group: Inhibitors. Alternative Names: MitoQ10 mesylate, Mitoubiquinone mesylate. CAS No. 845959-50-4. Pack Sizes: 5mg. Product ID: S8978. Formula: C38H47O7PS. Smiles: CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.CS(=O)(=O)[O-]. Storage Conditions: 2 years -20°C liquid. | United States; Europe |
| Mitoquinol | Mitoquinol is an orally active mitochondria-targeted antioxidant. Mitoquinol can regulate mitochondrial respiration and oxidation. Mitoquinol inhibits ROS production, and improves phagocytosis and glycolysis in ethanol-exposed macrophages via the HIF-1α-PFKP axis. Additionally, Mitoquinol can partially alleviate heat stress-induced decreases in growth performance, inflammatory responses, and metabolic disorders in pigs[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 845959-55-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124410. | |
| Mitoquinone mesylate | Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant in order to protect against oxidative damage[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MitoQ mesylate; MitoQ10 mesylate. CAS No. 845959-50-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-100116A. | |
| Mitoquinone mesylate | Mitoquinone mesylate, also known as MitoQ or MitoQ10; is a mitochondria-targeted antioxidant designed to accumulate within mitochondria in vivo in order to protect against oxidative damage. Alternative Names: MitoQ; Mito Q10; MitoQ10; MitoQ-10; Mitoubiquinone mesylate; Mitoquinone methanesulfonate. Grades: 98% , dissolved in ethanol-wate (1:1, v/v), 100~500 mg/mL. Please refer to the label on the sample vial for exact concentration. CAS No. 845959-50-4. Molecular formula: C38H47O7PS. Mole weight: 678.82. | |
| Mitoridine | Mitoridine. Group: Biochemicals. Grades: Plant Grade. CAS No. 3911-19-1. Pack Sizes: 10mg. Molecular Formula: C20H22N2O2, Molecular Weight: 322.4. US Biological Life Sciences. | Worldwide |
| Mitorubrin | Mitorubrin is a metabolite synthesized by phytotoxic fungi. Alternative Names: (-)-Mitorubrin; β-Resorcylic acid, 6-methyl-, ester with 7-hydroxy-7-methyl-3-propenyl-6H-2-benzopyran-6,8(7H)-dione (7CI,8CI). CAS No. 3403-71-2. Molecular formula: C21H18O7. Mole weight: 382.36. | |
| Mitorubrinic acid | Mitorubrinic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 58958-07-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C21H16O9. US Biological Life Sciences. | Worldwide |
| MitoSOX Red | MitoSOX Red is a live cell fluorescent probe that specifically targets mitochondria and is cell membrane permeable. MitoSOX Red enters mitochondria and is oxidized by superoxide but not by other ROS or RNS generating systems. The oxidized MitoSOX Red then binds to nucleic acids in mitochondria/nucleus, producing strong red fluorescence. MitoSOX Red can be used as a fluorescent indicator to specifically detect superoxide. In addition, superoxide dismutase (SOD) can prevent the oxidation of MitoSOX Red. Excitation/emission wavelength: 510/580 nm. Uses: Scientific research. Category: Signaling pathways. CAS No. 1003197-00-9. Pack Sizes: 100 μg; 100 μg * 5. Product ID: HY-D1055. | |
| MitoTam iodide, hydriodide | MitoTam iodide, hydriodide is a Tamoxifen derivative[1], an electron transport chain (ETC) inhibitor, spreduces mitochondrial membrane potential in senescent cells and affects mitochondrial morphology[2].MitoTam iodide, hydriodide is an effective anticancer agent, suppresses respiratory complexes (CI-respiration) and disrupts respiratory supercomplexes (SCs) formation in breast cancer cells[1][2]. MitoTam iodide, hydriodide causes apoptosis[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1634624-74-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-126222A. | |
| Mitotane | Mitotane (2,4-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2,4-DDD; o,p'-DDD. CAS No. 53-19-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-13690. | |
| Mitotane | Mitotane. Group: Biochemicals. Grades: Highly Purified. CAS No. 53-19-0. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C14H10Cl4. US Biological Life Sciences. | Worldwide |
| Mitotane-13C6 | Mitotane-13C6. Group: Biochemicals. Alternative Names: 1-Chloro-2-[2, 2-dichloro-1- (4-chlorophenyl) ethyl]benzene-13C6; 1, 1-Dichloro-2- (o-chlorophenyl) -2- (p-chlorophenyl) ethane-13C6; 1- (2-Chlorophenyl) -1- (4-chlorophenyl) -2, 2-dichloroethane-13C6; 1-(2'-Chlorophenyl)-1-(4'-chlorophenyl)-2,2-dichloroethane-13C6; 1-(o-Chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane-13C6; 2, 4'-Dichlorodiphenyl dichloroethane -13C6; 2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethane-13C6; 2-(p-Chlorophenyl)-2-(o-chlorophenyl)-1,1-dichloroethane-13C6; CB 313-13C6; Chloditan-13C6; Chlodithane-13C6; Lysodren-13C6; Mitotan-d4; NSC 38721-13C6; Opeprim-13C6; o,p'-DDD-13C6; o, p'-Dichlorodiphenyl dichloroethane -13C6; o,p'-TD-13C6. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C813C6H10Cl4, Molecular Weight: 326. US Biological Life Sciences. | Worldwide |
| Mitotane-13C6 | Mitotane-13C6 is the 13C labeled Mitotane[1]. Mitotane (2,4-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions[2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2,4-DDD-13C6; o,p'-DDD-13C6. CAS No. 1261396-21-7. Pack Sizes: 1 mg. Product ID: HY-13690S1. | |
| Mitotane-d4 | Mitotane-d4. Group: Biochemicals. Alternative Names: 1-Chloro-2-[2, 2-dichloro-1- (4-chlorophenyl) ethyl]benzene-d4; 1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane-d4; 1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane-d4; 1-(2'-Chlorophenyl)-1-(4'-chlorophenyl)-2,2-dichloroethane-d4; 1-(o-Chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane-d4; 2, 4'-Dichlorodiphenyl dichloroethane -d4; 2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethane-d4; 2-(p-Chlorophenyl)-2-(o-chlorophenyl)-1,1-dichloroethane-d4; CB 313-d4; Chloditan-d4; Chlodithane-d4; Lysodren-d4; Mitotan-d4; NSC 38721-d4; Opeprim-d4; o,p'-DDD-d4; o, p'-Dichlorodiphenyl dichloroethane -d4; o,p'-TDE-d4. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C14H6D4Cl4, Molecular Weight: 324.07. US Biological Life Sciences. | Worldwide |
| Mito-TEMPO | Mito-TEMPO (MT), a mitochondria-targeted superoxide dismutase mimetic, protects against the early phase of acetaminophen (APAP) hepatotoxicity by inhibiting peroxynitrite formation. Mito-TEMPO treatment inhibits APAP-induced RIP3 kinase expression. Group: Inhibitors. CAS No. 1334850-99-5. Pack Sizes: 5mg. Product ID: S9733. Formula: C29H35N2O2P.Cl. Smiles: [Cl-].CC1(C)CC(CC(C)(C)N1[O])NC(=O)C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4. | United States; Europe |
| Mito-TEMPO | Mito-TEMPO is a mitochondria-targeted antioxidant. Mito-TEMPO induces mitophagy by activating the PINK1/Parkin pathway, inhibits NLRP3 inflammasome activation, restores mitochondrial membrane potential, and improves renal function and podocyte injury. Mito-TEMPO regulates Ca2+ homeostasis, inhibits Bnip3 overexpression, shortens action potential duration, and exerts antiarrhythmic effects. Mito-TEMPO reverses premature senescence, reduces trabecular bone loss, and decreases cell apoptosis. Mito-TEMPO can be used in studies of chronic kidney disease, age-related cardiac dysfunction, postmenopausal osteoporosis, and ischemic stroke[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1334850-99-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112879. | |
| MitoTEMPO hydrate | MitoTEMPO hydrate is a mitochondria-targeted antioxidant. MitoTEMPO hydrate induces mitophagy by activating the PINK1/Parkin pathway, inhibits NLRP3 inflammasome activation, restores mitochondrial membrane potential, and improves renal function and podocyte injury. MitoTEMPO hydrate regulates Ca2+ homeostasis, inhibits Bnip3 overexpression, shortens action potential duration, and exerts antiarrhythmic effects. MitoTEMPO hydrate reverses premature senescence, reduces trabecular bone loss, and decreases cell apoptosis. MitoTEMPO hydrate can be used in studies of chronic kidney disease, age-related cardiac dysfunction, postmenopausal osteoporosis, and ischemic stroke[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1569257-94-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125944. | |
| MitoTEMPOL | MitoTEMPOL is a a mitochondria-targeted nitroxide that reduces mitochondrial O2-to H2O2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1101113-39-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-115386. | |
| MitoTEMPOL | MitoTEMPOL. CAS No. 1101113-39-6. | |
| Mitotic kinesin-IN-1 hydrochloride | Mitotic kinesin-IN-1 (Example 80) hydrochloride is a Mitotic kinesin inhibitor. Mitotic kinesin-IN-1 hydrochloride inhibits cell proliferation by suppressing mitosis. Mitotic kinesin-IN-1 hydrochloride can be used for cancer, cardiac hypertrophy, immune and inflammatory disorders, fungal infections research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1018690-45-3. Pack Sizes: 1 mg. Product ID: HY-177246A. | |
| MitoTracker Deep Red FM | MitoTracker Deep Red (MTDR) FM fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Deep Red FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 644/665 nm[1]. MitoTracker Deep Red dyes have an excitation/emission wavelength of 633/650-750 nm[2].The Ex/Em of MitoTracker Deep Red (MTDR) FM is 644/665 nm. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MTDR FM. CAS No. 873315-86-7. Pack Sizes: 50 μg; 100 μg. Product ID: HY-D1783. | |
| MitoTracker Green FM | Mito-Tracker Green is a green fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Green FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 490/523 nm. Uses: Scientific research. Category: Signaling pathways. CAS No. 201860-17-5. Pack Sizes: 50 μg. Product ID: HY-135056. | |
| MitoTracker Green FM (solution) | Mito-Tracker Green (solution) is a green fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Green FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 490/523 nm.Solvent and concentration: DMSO: 1 mM. Uses: Scientific research. Category: Signaling pathways. CAS No. 201860-17-5. Pack Sizes: 20 μL; 50 μL. Product ID: HY-DY1032. | |
| MitoTracker Orange CMTMRos | MitoTracker Orange CMTMRos is a fluorescent dye that labels mitochondria within live cells utilizing the mitochondrial membrane potential (Ex/Em: 551/576 nm)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 199116-50-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D1696. | |
| Mitoxantrone | 50mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H28N4O6. CAS No. 65271-80-9. Prepack ID 28035650-50mg. Molecular Weight 444.48. See USA prepack pricing. | |
| Mitoxantrone | Mitoxantrone is a type II topoisomerase inhibitor with IC50 of 2.0 μM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively. It is used in the treatment of certain types of cancer, mostly metastatic breast cancer, acute myeloid leukemia, and non-Hodgkin's lymphoma. Uses: Analgesics. Alternative Names: mitoxantrone; 65271-80-9; Mitoxanthrone; Mitozantrone; DHAQ. Grades: >98%. CAS No. 65271-80-9. Molecular formula: C22H28N4O6. Mole weight: 444.48. | |
| Mitoxantrone | Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity[1][2][3][4]. Mitoxantrone also has anti-orthopoxvirus activity with EC50s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mitozantrone; NSC 301739. CAS No. 65271-80-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-13502. | |
| Mitoxantrone | Mitoxantrone is a DNA intercalating drug. Mitoxantrone inhibits DNA synthesis. Mitoxantrone is used as an anti-cancer agent. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione; 1, 4-Bis [ (2- (2- hydroxyethylamino) ethyl) amino] -5, 8-di hydroxyanthraquinone. Grades: Highly Purified. CAS No. 65271-80-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Mitoxantrone (2-hydroxyethyl) piperazine impurity(mitoxantrone impurity D) | Mitoxantrone (2-hydroxyethyl) piperazine impurity(mitoxantrone impurity D). Group: Biochemicals. Alternative Names: 1, 2, 3, 4-Tetrahydro-8, 11-dihydroxy-4- (2-hydroxyethyl) -6- [ [2- [ (2-hydroxyethyl) amino] ethyl] amino] naphtho [2, 3-f] quinoxaline-7, 12-dione; Mitoxantrone impurity D. Grades: Highly Purified. CAS No. 137132-70-8. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C22H26N4O6. US Biological Life Sciences. | Worldwide |
| Mitoxantrone (2-Hydroxyethyl) piperazine Impurity (Mitoxantrone Impurity D) | A metabolite of the anticancer agent Mitoxantrone. Group: Biochemicals. Alternative Names: 1, 2, 3, 4-Tetrahydro-8, 11-dihydroxy-4- (2-hydroxyethyl) -6- [ [2- [ (2-hydroxyethyl) amino] ethyl] amino] naphtho [2, 3-f] quinoxaline-7, 12-dione; Mitoxantrone Impurity D. Grades: Highly Purified. CAS No. 137132-70-8. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Mitoxantrone dihydrochloride | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H28N4O6 · 2HCl. CAS No. 70476-82-3. Prepack ID 24343907-1g. Molecular Weight 517.4. See USA prepack pricing. | |
| Mitoxantrone dihydrochloride | It is a type II topoisomerase inhibitor with IC50 of 2.0 μM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively. Mitoxantrone dihydrochloride is an antiviral, antibacterial, antiprotozoal, immunomodulating and antineoplastic anthraquinone derivative. Alternative Names: 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione dihydrochloride; DHAQ; CL-232325; CL 232325; CL232325; Novantrone; Mitroxone; Neotalem; Onkotrone; Pralifan; Mitoxantrone 2HCl; Immunex. Grades: >98%. CAS No. 70476-82-3. Molecular formula: C22H28N4O6.2HCl. Mole weight: 517.40. | |
| Mitoxantrone dihydrochloride | Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity[1][2][3][4]. Mitoxantrone dihydrochloride also has anti-orthopoxvirus activity with EC50s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mitozantrone dihydrochloride; NSC 301739 dihydrochloride. CAS No. 70476-82-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-13502A. | |
| Mitoxantrone Dihydrochloride | Mitoxantrone is a DNA intercalating drug. Mitoxantrone inhibits DNA synthesis. Mitoxantrone is used as an anti-cancer agent. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione Hydrochloride; Bisantrone; CL 232315; DHAD; Immunex; Mitoxantrone Hydrochloride; NCI 301739; NSC 301739; Novantron; Novantrone; Novatrone. Grades: Highly Purified. CAS No. 70476-82-3. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Mitoxantrone EP Impurity A | Mitoxantrone EP Impurity A. Uses: For analytical and research use. CAS No. 89991-52-6. Molecular formula: C18H19N3O5. Mole weight: 357.37. Catalog: APB89991526. | |
| Mitoxantrone EP Impurity B | Mitoxantrone EP Impurity B. Uses: For analytical and research use. CAS No. 80189-44-2. Molecular formula: C22H28N4O5. Mole weight: 428.49. Catalog: APB80189442. | |
| Mitoxantrone EP Impurity C | Mitoxantrone EP Impurity C. Uses: For analytical and research use. CAS No. 1796928-50-1. Molecular formula: C22H27ClN4O6. Mole weight: 478.93. Catalog: APB1796928501. | |
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