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N-ε-Carbobenzoxy-L-lysine N-methylamide hydrochloride. Alternative Names: H-Lys(Z)-NHMe HCl. CAS No. 64569-70-6. Molecular formula: C15H24ClN3O3. Mole weight: 329.82.
Nε-(Carboxymethyl)-L-lysine
Nε-(Carboxymethyl)-L-lysine (CML) is an orally active advanced glycation end product. Nε-(Carboxymethyl)-L-lysine upregulates the expression of PLK1 and CEP20, and induces the activation of RAGE and ERK/NFκB. Nε-(Carboxymethyl)-L-lysine drives centrosome amplification. Nε-(Carboxymethyl)-L-lysine induces malignant transformation of hepatocytes and promotes the development of hepatocellular carcinoma. Nε-(Carboxymethyl)-L-lysine induces epithelial-mesenchymal transition in osteosarcoma cells and enhances their migration and invasion properties[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CML; N6-(Carboxymethyl)-L-lysine; Nε-(1-Carboxymethyl)-L-lysine. CAS No. 5746-4-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W286743.
Nε-Carboxymethyl-L-lysine
N(6)-Carboxymethyllysine (CML), also known as N(epsilon)-(carboxymethyl)lysine, is an advanced glycation endproduct(AGE). CML has been the most used marker for AGEs in food analysis. Uses: Cel and cml are two stable, nonenzymatic chemical modifications of protein lysine residues resulting from glycation and oxidation reactions. Alternative Names: Lys(Cm); 2-Amino-6-(carboxymethyl-amino)-hexanoic Acid; N6-(Carboxymethyl)lysine; N6-(Carboxymethyl)-L-lysine; CML; Nε-(1-Carboxymethyl)-L-lysine; Ne-Carboxymethyl-L-lysine; NECML; N(epsilon)-(Carboxymethyl)lysine; (S)-2-Amino-6-(carboxymethylamino)hexanoic acid; (2S)-2-amino-6-(carboxymethylamino)hexanoic acid; n'-(carboxymethyl)lysine. Grades: ≥ 97% (Assay by titration). CAS No. 5746-4-3. Molecular formula: C8H16N2O4. Mole weight: 204.22.
Nε-Crotonyl-L-lysine
A reagent used in peptide synthesis and drug screening. Alternative Names: L-Lys(crotonyl)-OH; (S)-2-Amino-6-(but-2-enamido)hexanoic acid; N6-(1-Oxo-2-buten-1-yl)-L-lysine. Grades: ≥ 99% (HPLC). CAS No. 1338823-35-0. Molecular formula: C10H18N2O3. Mole weight: 214.20.
N-ε-Isopropyl-L-lysine is an alkylated version of Lysine. H-Lysine(Isopropyl)-OH was found in the plasma and urine of rats fed with isopropylated casein. Alternative Names: H-Lys(Isopropyl)-OH. CAS No. 5977-9-3. Molecular formula: C9H20N2O2. Mole weight: 188.27.
Used for the preparation of sugar specific antibodies using liposomes. Uses: Used for the preparation of sugar specific antibodies using liposomes. Alternative Names: [6-(β-D-Galactopyranosylamino)-6-oxohexyl]carbamic Acid Phenylmethyl Ester; N-N-Benzyloxycarbonyl-ε-aminocaproyl-β-D-galactopyranosylamine. CAS No. 38822-58-1. Molecular formula: C20H30N2O8. Mole weight: 426.46.
N-ε,N-ε-Dimethyl-L-lysine hydrochloride
N-ε,N-ε-Dimethyl-L-lysine hydrochloride. Alternative Names: H-Lys(Me2)-OH HCl. Grades: ≥ 95%. CAS No. 79416-87-8. Molecular formula: C8H19ClN2O2. Mole weight: 210.70.
N-ε,N-ε,N-ε-Trimethyl-L-lysinium chloride hydrochloride. CAS No. 14039-75-9. Purity: 96%. Product ID: ACM14039759. Mole weight: 260.18. Alfa Chemistry - ISO 9001:32057 Certified.
Nε,Nε,Nε-Trimethyllysine chloride
Nε,Nε,Nε-Trimethyllysine chloride serves as a precursor for gut flora-dependent formation of N,N,N-trimethyl-5-aminovaleric acid (TMAVA)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ne-(Trimethyl)-L-lysine chloride; H-Lys(Me)3-OH chloride. CAS No. 55528-53-5. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N7404.
Used in the preparation of lipophilic human glucagon-like peptide-1 derivatives with protracted action profiles. Group: Biochemicals. Alternative Names: Nε-Palmitoyl-Glu-γ-succinimidyl-α-tert-butyl Ester; (2S)-. Grades: Highly Purified. CAS No. 204521-63-1. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Nε-Palmitoyl-L-lysine
Nε-Palmitoyl-L-lysine. Alternative Names: H-L-Lys(Palm)-OH; N6-Palmitoyl-L-lysine; N6-Hexadecanoyllysine; N6-(1-Oxohexadecyl)-L-lysine. Grades: > 98%. CAS No. 59012-43-0. Molecular formula: C22H44N2O3. Mole weight: 384.60.
A modified amino acid (L-lysine) for cancer therapy development. Alternative Names: H-L-Lys(Poc) HCl; (S)-Amino-6-((prop-2-ynyloxy)carbonylamino)hexanoic acid hydrochloride; H-L-Lys(Pryoc)-OH HCl. Grades: 98.0-101.5% (Assay by titration). CAS No. 1428330-91-9. Molecular formula: C10H16N2O4·HCl. Mole weight: 264.70.
N-ε-propargyloxycarbonyl-L-lysine
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals[1][2]. N-ε-propargyloxycarbonyl-L-lysine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: H-L-Lys(Poc)?-OH. CAS No. 1215204-46-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139014.
N-ε-propargyloxycarbonyl-L-lysine hydrochloride
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals[1][2]. N-ε-propargyloxycarbonyl-L-lysine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: H-L-Lys(Poc)?-OH hydrochloride. CAS No. 1428330-91-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128676.
N-ε-(p-Toluenesulfonyl)-L-lysine
N-ε-(p-Toluenesulfonyl)-L-lysine. Alternative Names: H-Lys(Tos)-OH. CAS No. 2130-76-9. Molecular formula: C13H20N2O4S. Mole weight: 300.37.
Nε-Z-L-lysine methyl ester hydrochloride (CAS 27894-50-4). CAS No. 27894-50-4. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
NeQuinate. Group: Biochemicals. Grades: Highly Purified. CAS No. 13997-19-8. Pack Sizes: 5mg, 10mg, 25mg. US Biological Life Sciences.
Worldwide
Neramexane
Neramexane is a drug related to memantine, which acts as an NMDA antagonist and has neuroprotective effects. Alternative Names: KRP-209; 1,3,3,5,5-Pentamethylcyclohexanamine. Grades: > 95%. CAS No. 219810-59-0. Molecular formula: C11H23N. Mole weight: 169.31.
Neramexane mesylate
Neramexane mesylate. Group: Biochemicals. Grades: Highly Purified. CAS No. 457068-92-7. Pack Sizes: 50g, 100g. Molecular Formula: C11H23N·CH4O3S. US Biological Life Sciences.
Worldwide
Nerandomilast
Nerandomilast is an inhibitor of phosphodiesterase 4B (PDE4B) used for the treatment of an idiopathic pulmonary fibrosis, progressive pulmonary fibrosis (PPF) and interstitial lung disease. Alternative Names: BI 1015550; BI-1015550; BI1015550. Grades: 98% by HPLC. CAS No. 1423719-30-5. Molecular formula: C20H25ClN6O2S. Mole weight: 449.0.
Nerandomilast
Nerandomilast (BI 1015550) is an orally active inhibitor of PDE4B with an IC50 value of 7.2 nM. Nerandomilast has good safety and potential applications in inflammation, allergic diseases, pulmonary fibrosis, and chronic obstructive pulmonary disease (COPD)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BI 1015550. CAS No. 1423719-30-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153192.
Nerandomilast (BI 1015550)
Nerandomilast (BI 1015550) is an orally active inhibitor of PDE4B with IC50 of 7.2 nM. It has good safety and potential applications in inflammation, allergic diseases, pulmonary fibrosis, and chronic obstructive pulmonary disease (COPD). Group: Inhibitors. CAS No. 1423719-30-5. Pack Sizes: 5mg. Product ID: E1382. Formula: C20H25ClN6O2S. Storage Conditions: 3 years -20°C powder.
United States; Europe
Neranic acid
Neranic acid. CAS No. 4613-38-1.
Neratinib
Neratinib, also known as HKI-272 or PB272, is an orally available, 6,7-disubstituted-4-anilinoquinoline-3-carbonitrile irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER-2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP-binding pocket of the receptor. Treatment of cells with this agent results in inhibition of downstream signal transduction events and cell cycle regulatory pathways; arrest at the G1-S (Gap 1/DNA synthesis)-phase transition of the cell division cycle; and ultimately decreased cellular proliferation. Neratinib also inhibits the epidermal growth factor receptor (EGFR) kinase and the proliferation of EGFR-dependent cells. Alternative Names: 2-Butenamide, N-[4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-, (2E)-; (2E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide; (E)-N-[4-[3-Chloro-4-[(2-pyridinyl)methoxy]anilino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide; (E)-N-[4-[[3-Chloro-4-((pyridin-2-yl)methoxy)phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)-2-butenamide; HKI 272; HKI-272; HKI272; PB-272; PB 272; PB 272. Grades: >98%. CAS No. 698387-09-6. Molecular formula: C30H29ClN6O3. Mole weight: 557.04.
Neratinib
Neratinib (HKI-272) is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC50s of 59 nM and 92 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HKI-272. CAS No. 698387-09-6. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-32721.
Neratinib
Neratinib. Group: Biochemicals. Alternative Names: (2E) -N-[4-[[3-Chloro-4- (2-pyridinylmethoxy) phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4- (dimethylamino) -2-butenamide; HKI 272. Grades: Highly Purified. CAS No. 698387-09-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Neratinib (HKI-272)
Neratinib is a highly selective HER2 and EGFR inhibitor with IC50 of 59 nM and 92 nM in cell-free assays; weakly inhibits KDR and Src, no significant inhibition to Akt, CDK1/2/4, IKK-2, MK-2, PDK1, c-Raf and c-Met. Phase 3. Group: Inhibitors. Alternative Names: HKI-272. CAS No. 698387-09-6. Pack Sizes: 5mg. Product ID: S2150. Formula: C30H29ClN6O3. Smiles: CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Neratinib Impurity 12
Neratinib Impurity 12. Uses: For analytical and research use. CAS No. 1144516-21-1. Molecular formula: C29H27ClN6O2. Mole weight: 527.02. Catalog: APB1144516211.