A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
N(6)-Carboxymethyllysine (CML), also known as N(epsilon)-(carboxymethyl)lysine, is an advanced glycation endproduct(AGE). CML has been the most used marker for AGEs in food analysis. Uses: Cel and cml are two stable, nonenzymatic chemical modifications of protein lysine residues resulting from glycation and oxidation reactions. Synonyms: Lys(Cm); 2-Amino-6-(carboxymethyl-amino)-hexanoic Acid; N6-(Carboxymethyl)lysine; N6-(Carboxymethyl)-L-lysine; CML; Nε-(1-Carboxymethyl)-L-lysine; Ne-Carboxymethyl-L-lysine; NECML; N(epsilon)-(Carboxymethyl)lysine; (S)-2-Amino-6-(carboxymethylamino)hexanoic acid; (2S)-2-amino-6-(carboxymethylamino)hexanoic acid; n'-(carboxymethyl)lysine. Grade: ≥ 97% (Assay by titration). CAS No. 5746-4-3. Molecular formula: C8H16N2O4. Mole weight: 204.22.
Nε-Crotonyl-L-lysine
A reagent used in peptide synthesis and drug screening. Synonyms: L-Lys(crotonyl)-OH; (S)-2-Amino-6-(but-2-enamido)hexanoic acid; N6-(1-Oxo-2-buten-1-yl)-L-lysine. Grade: ≥ 99% (HPLC). CAS No. 1338823-35-0. Molecular formula: C10H18N2O3. Mole weight: 214.20.
N-ε-Isopropyl-L-lysine is an alkylated version of Lysine. H-Lysine(Isopropyl)-OH was found in the plasma and urine of rats fed with isopropylated casein. Synonyms: H-Lys(Isopropyl)-OH. CAS No. 5977-9-3. Molecular formula: C9H20N2O2. Mole weight: 188.27.
Nepsilon,Nepsilon,Nepsilon-Trimethyl-[13C3]-L-lysine hydrochloride is an isotopic labelled derivative of L-lysine. L-Lysine is an essential amino acid obtained from red meats and fish. Lysine inhibits HSV growth via knocking out arginine. It is also used in the labelling of human bone marrow mesenchymal stem cells for analysis. Synonyms: Nepsilon,Nepsilon,Nepsilon-Trimethyl-13C3-L-lysine hydrochloride; Nε,Nε,Nε-Trimethyl-13C3-L-lysine hydrochloride. Grade: 97% by HPLC; 99% atom 13C. Molecular formula: C6[13C]3H20N2O2.HCl. Mole weight: 227.71.
Used in the preparation of lipophilic human glucagon-like peptide-1 derivatives with protracted action profiles. Group: Biochemicals. Alternative Names: Nε-Palmitoyl-Glu-γ-succinimidyl-α-tert-butyl Ester; (2S)-. Grades: Highly Purified. CAS No. 204521-63-1. Pack Sizes: 100mg. US Biological Life Sciences.
A modified amino acid (L-lysine) for cancer therapy development. Synonyms: H-L-Lys(Poc) HCl; (S)-Amino-6-((prop-2-ynyloxy)carbonylamino)hexanoic acid hydrochloride; H-L-Lys(Pryoc)-OH HCl. Grade: 98.0-101.5% (Assay by titration). CAS No. 1428330-91-9. Molecular formula: C10H16N2O4·HCl. Mole weight: 264.70.
N-ε-propargyloxycarbonyl-L-lysine hydrochloride
N-?-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride is a lysine-based unnatural amino acid (UAA). N-?-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals[1][2]. N-?-propargyloxycarbonyl-L-lysine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: H-?L-?Lys(Poc)?-?OH hydrochloride. CAS No. 1428330-91-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128676.
NeQuinate. Group: Biochemicals. Grades: Highly Purified. CAS No. 13997-19-8. Pack Sizes: 5mg, 10mg, 25mg. US Biological Life Sciences.
Worldwide
Nequinate-[d7]
Nequinate-[d7] is the labelled analogue of Nequinate, which is a medication used for the treatment of coccidiosis. It is only approved for veterinary use in some countries. Synonyms: Nequinate-D7; Methyl 6-Butyl-4-oxo-7-((phenyl-d5)methoxy-d2)-1,4-dihydroquinoline-3-carboxylate; 7-Benzyloxy-D7-6-butyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid methyl ester; Methyl benzoquate-d7; Statil-d7; Statoquate-d7; Statyl-d7; Tranil-d7. Grade: 95% by HPLC; 98% atom D. CAS No. 1584701-10-9. Molecular formula: C22H16D7NO4. Mole weight: 372.47.
Neramexane mesylate
Neramexane mesylate. Group: Biochemicals. Grades: Highly Purified. CAS No. 457068-92-7. Pack Sizes: 50g, 100g. Molecular Formula: C11H23N·CH4O3S. US Biological Life Sciences.
Worldwide
Nerandomilast
Nerandomilast (BI 1015550) is an orally active inhibitor of PDE4B with an IC 50 value of 7.2 nM. Nerandomilast has good safety and potential applications in inflammation, allergic diseases, pulmonary fibrosis, and chronic obstructive pulmonary disease (COPD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 1015550. CAS No. 1423719-30-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153192.
Neratinib
Neratinib, also known as HKI-272 or PB272, is an orally available, 6,7-disubstituted-4-anilinoquinoline-3-carbonitrile irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER-2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP-binding pocket of the receptor. Treatment of cells with this agent results in inhibition of downstream signal transduction events and cell cycle regulatory pathways; arrest at the G1-S (Gap 1/DNA synthesis)-phase transition of the cell division cycle; and ultimately decreased cellular proliferation. Neratinib also inhibits the epidermal growth factor receptor (EGFR) kinase and the proliferation of EGFR-dependent cells. Alternative Names: HKI-272. Neratinib (HKI-272). Nerlynx. CAS No. 698387-09-6. Product ID: API698387096. Molecular formula: C30H29ClN6O3. Mole weight: 557. EINECS: 811-237-1. SMILES: CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C. Appearance: Solid powder. Category: Anti-Tumor APIs.
Neratinib
Neratinib (HKI-272) is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC 50 s of 59 nM and 92 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HKI-272. CAS No. 698387-09-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-32721.
Neratinib
Neratinib. Group: Biochemicals. Alternative Names: (2E) -N-[4-[[3-Chloro-4- (2-pyridinylmethoxy) phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4- (dimethylamino) -2-butenamide; HKI 272. Grades: Highly Purified. CAS No. 698387-09-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Neratinib Impurity 33
Neratinib Impurity 33. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1222172-49-7. Molecular formula: C12H16N2O4. Mole weight: 252.27. Catalog: APB1222172497.
Neratinib Impurity 34
Neratinib Impurity 34. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1222172-50-0. Molecular formula: C15H17N3O4. Mole weight: 303.32. Catalog: APB1222172500.
Neratinib Impurity 6
Neratinib Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102137-46-2. Molecular formula: C12H12N2O. Mole weight: 200.24. Catalog: APB102137462.
Neratinib Impurity 8
Neratinib Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 105326-69-0. Molecular formula: C12H11ClN2O. Mole weight: 234.68. Catalog: APB105326690.
Neratinib maleate
Neratinib (HKI-272) maleate is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC 50 s of 59 nM and 92 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HKI-272 maleate. CAS No. 915942-22-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32721B.
Neratinib Maleate
Neratinib Maleate is the maleate salt form of neratinib, an orally available, quinazoline-based, irreversible inhibitor of both the receptor tyrosine kinases (RTKs) human epidermal growth factor receptor 2 (HER2; ERBB2) and human epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Alternative Names: hki-272 maleate. Nerlynx. Neratinib maleate [MI]. CAS No. 915942-22-2. Product ID: API915942222. Molecular formula: C34H33ClN6O7. Mole weight: 673.1. EINECS: 620-527-5. SMILES: CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C.C(=CC(=O)O)C(=O)O. Category: Anti-Tumor APIs.
Neridronate
Neridronate. Group: Biochemicals. Alternative Names: 6-Amino-1-hydroxyhexylidene bisphosphonic acid. Grades: Highly Purified. CAS No. 79778-41-9. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C6H17NO7P2. US Biological Life Sciences.
Neridronate is an aminobisphosphonate, licensed in Italy for the treatment of osteogenesis imperfecta (OI) and Pagets disease of bone (PDB). Neridronate is effective also in other skeletal diseases such as osteoporosis, algodystrophy, hypercalcemia of malignancy, and bone metastases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 79778-41-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119443.
Neridronate, Sodium Salt (Nerixia Sodium Salt)
A biphosphonate bone resorption inhibitor. Used as a treatment for osteogenesis imperfecta. Group: Biochemicals. Alternative Names: Nerixia Sodium Salt. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Nerigliatin
Nerigliatin (PF-04937319) is a orally active glucokinase activator ( GKA ) with EC 50 value of 154.4 μM. Nerigliatin maintains glucose-lowering efficacy. Nerigliatin causes peripheral nerve degeneration. Nerigliatin can be used in type 2 diabetes research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-04937319. CAS No. 1245603-92-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108328.
Neriifolin
Neriifolin, a CNS-penetrating cardiac glycoside, is an inhibitor of the Na+, K+-ATPase. Neriifolin can target beclin 1, inhibits the formation of LC3-associated phagosomes and ameliorates experimental autoimmune encephalomyelitis (EAE) development. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells[2. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 466-07-9. Molecular formula: C30H46O8. Mole weight: 534.68. Purity: 0.99. Canonical SMILES: O[C@@]12[C@@]3([H])[C@@](CC[C@@]1([C@](C4=CC(OC4)=O)([H])CC2)C)([H])[C@@]5([C@](C[C@H](CC5)O[C@H]6[C@H]([C@@H]([C@H]([C@@H](O6)C)O)OC)O)([H])CC3)C. Product ID: ACM466079. Alfa Chemistry ISO 9001:2015 Certified.
Neritaloside
Neritaloside is isolated from the herbs of Nerium indicum Mill. It exhibits central nervous system depressant activity in mic. Synonyms: 16-Acetylstrospeside; Strospeside, 16-acetate; Card-20(22)-enolide, 16-(acetyloxy)-3-((6-deoxy-3-O-methyl-beta-D-galactopyranosyl)oxy)-14-hydroxy-, (3-beta,5-beta,16-beta)-. Grade: 95%. CAS No. 465-13-4. Molecular formula: C32H48O10. Mole weight: 592.73.
Nerol
analytical standard. Group: Flavor and fragrance standards.
Nerol
Nerol. Group: Biochemicals. Alternative Names: (2Z)-3,7-Dimethyl-2,6-octadien-1-ol; (Z)-3,7-Dimethyl-2,6-octadien-1-ol; (Z)-3,7-Dimethyl-2,6-octadienol; (Z)-Geraniol; (Z)-Nerol; 2-cis-3,7-Dimethyl-2,6-octadien-1-ol; 3,7-Dimethyl-cis-2,6-octadien-1-ol; Nerol 900; Neryl Alcohol; cis-3,7-Dimethyl-2,6-octadien-1-ol; cis-Geraniol; β-Nerol. Grades: Highly Purified. CAS No. 106-25-2. Pack Sizes: 10g. Molecular Formula: C10H18O, Molecular Weight: 154.25. US Biological Life Sciences.
Worldwide
Nerol
Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca 2+ and ROS. Antifungal activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 106-25-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-N7063.
Nerol 90
Nerol 90. CAS No. 106-25-2. FEMA No. 2770. Kosher: Y. VIGON Item # 503580. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers.
America & Internationally
Nerolidol
mixture of cis and trans, analytical standard. Group: Flavor and fragrance standards.
Nerolidol
Nerolidol is a natural membrane-active sesquiterpene, with antitumor, antibacterial, antifungal and antiparasitic activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Methylvinylhomogeranyl carbinol. Product Category: Inhibitors. Appearance: Oil. CAS No. 7212-44-4. Molecular formula: C15H26O. Mole weight: 222.37. Purity: 99%+. IUPACName: (6E)-3,7,11-Trimethyldodeca-1,6,10-trien-3-ol. Canonical SMILES: CC(=CCCC(=CCCC(C)(C=C)O)C)C. Density: 0.875 g/mL at 25 °C(lit.). Product ID: ACM7212444-1. Alfa Chemistry ISO 9001:2015 Certified.
Nerolidol
Nerolidol. CAS No. 7212-44-4. FEMA No. 2772. Kosher: Y. VIGON Item # 500925. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers.
America & Internationally
Nerolidol
Nerolidol has multiple natural membrane activities, possesses anti-cancer, anti-inflammatory, antibacterial and anti-insect activity. Nerolidol Suppresses parasitic activity, suppresses bloodsucking diseases, bloodworm diseases, and other diseases. Nerolidol can protect the cells from lipid and protein properties, damage to DNA, and protect the cells from damage [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 7212-44-4. Pack Sizes: 10 mM * 1 mL; 5 g; 25 g; 50 g. Product ID: HY-N1944.