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| Product | Description | |
|---|---|---|
| Nevirapine | Nevirapine. Group: Biochemicals. Grades: Highly Purified. CAS No. 129618-40-2. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C15H14N4O. US Biological Life Sciences. |  Worldwide |
| Nevirapine (11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2,3-e][1,4]diazepin-6-one) | A potent (IC50=84nM) and selective non-nucleoside inhibitorf HIV-1 reverse transcriptase. Group: Biochemicals. Alternative Names: 11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2,3-e][1,4]diazepin-6-one. Grades: Highly Purified. Pack Sizes: 5mg, 10mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| Nevirapine-d3 | Nevirapine-d3 (BI-RG 587-d3) is the deuterium labeled Nevirapine. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1051419-24-9. Pack Sizes: 500 μg; 1 mg. Product ID: HY-10570S1. |  |
| Nevirapine-d3 | Labeled Nevirapine , a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Antiviral. Group: Biochemicals. Alternative Names: 11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2,3-e][1,4]diazepin-6-one-d3; BI-RG 587-d3; NSC 641530-d3; Nevarapine-d3; Viramune-d3. Grades: Highly Purified. CAS No. 1051419-24-9. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Nevirapine-[d3] | Nevirapine-[d3] is the labelled analogue of Nevirapine. Nevirapine is an anti-HIV drug that reduces the amount of virus in the body. Uses: Labelled nevirapine (n391275), a potent (ic50=84nm) and selective non-nucleoside inhibitor of hiv-1 reverse transcriptase. antiviral. Synonyms: Nevirapine D3. Grade: 95% atom D. CAS No. 1051419-24-9. Molecular formula: C15H11D3N4O. Mole weight: 269.32. |  |
| Nevirapine-[d4] | Nevirapine-[d4] is the labelled analogue of Nevirapine, which is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS. Synonyms: Nevirapine D4; 11-cyclopropyl-2,2,3,3-d4-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one. Grade: 95% by HPLC; 95% atom D. CAS No. 1051418-95-1. Molecular formula: C15H10D4N4O. Mole weight: 270.33. | |
| Nevirapine-[d5] | Nevirapine-[d5] is the labelled analogue of Nevirapine, which is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS. Synonyms: Nevirapine D5. Grade: 95% by HPLC; 95% atom D. CAS No. 1189717-29-0. Molecular formula: C15H9D5N4O. Mole weight: 271.33. | |
| Nevirapine-d5 (11-Cyclopropyl-d4-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2,3-e][1,4]diazepin-6-one) | Labelled Nevirapine, a potent (IC50=84nM) and selective non-nucleoside inhibitorf HIV-1 reverse transcriptase. Group: Biochemicals. Alternative Names: 11-Cyclopropyl-d4-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2,3-e][1,4]diazepin-6-one. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Nevirapine EP Impurity D | Nevirapine EP Impurity D. Uses: For analytical and research use. CAS No. 1391054-30-0. Molecular formula: C30H26N8O2. Mole weight: 530.59. Catalog: APB1391054300. |  |
| Nevirapine Related Compound A | Nevirapine Related Compound A. Uses: For analytical and research use. CAS No. 133627-17-5. Mole weight: 254.29. Catalog: AP133627175. | |
| Nevirapine Related Compound B | Nevirapine Related Compound B. Uses: For analytical and research use. CAS No. 287980-84-1. Mole weight: 226.23. Catalog: AP287980841. | |
| Nevirapine Related Compound C | Nevirapine Related Compound C. Uses: For analytical and research use. CAS No. 287980-85-2. Mole weight: 268.31. Catalog: AP287980852. | |
| Nevirapine (Standard) | Nevirapine (Standard) is the analytical standard of Nevirapine. This product is intended for research and analytical applications. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BI-RG 587 (Standard); NSC 641530 (Standard); NVP (Standard). CAS No. 129618-40-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10570R. | |
| New Coccine | New Coccine. Group: Biochemicals. Grades: Reagent Grade. CAS No. 2611-82-7. Pack Sizes: 25g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| New Indocyanine Green | New Indocyanine Green. CAS No. 172616-80-7. Molecular formula: C46H50ClN2NaO6S2. Mole weight: 849.5g/mol. IUPAC Name: sodium;4-[2-[2-[2-chloro-3-[2-[1,1-dimethyl-3-(4-sulfonatobutyl)benzo[e]indol-3-ium-2-yl]ethenyl]cyclohex-2-en-1-ylidene]ethylidene]-1,1-dimethylbenzo[e]indol-3-yl]butane-1-sulfonate. SMILES: CC1(C(=[N+](C2=C1C3=CC=CC=C3C=C2)CCCCS(=O)(=O)[O-])C=CC4=C(C(=CC=C5C(C6=C(N5CCCCS(=O)(=O)[O-])C=CC7=CC=CC=C76)(C)C)CCC4)Cl)C.[Na+]. InChI: InChI=1S/C46H51ClN2O6S2.Na/c1-45(2)40(48(28-9-11-30-56(50,51)52)38-24-20-32-14-5-7-18-36(32)42(38)45)26-22-34-16-13-17-35(44(34)47)23-27-41-46(3,4)43-37-19-8-6-15-33(37)21-25-39(43)49(41)29-10-12-31-57(53,54)55;/h5-8,14-15,18-27H,9-13,16-17,28-31H2,1-4H3,(H-,50,51,52,53,54,55);/q;+1/p-1. |  |
| New indocyanine Green, Dye content 80% | New indocyanine Green, Dye content 80%. CAS No. 172616-80-7. Molecular formula: C46H50ClN2NaO6S2. Mole weight: 849.5g/mol. IUPAC Name: sodium;4-[2-[2-[2-chloro-3-[2-[1,1-dimethyl-3-(4-sulfonatobutyl)benzo[e]indol-3-ium-2-yl]ethenyl]cyclohex-2-en-1-ylidene]ethylidene]-1,1-dimethylbenzo[e]indol-3-yl]butane-1-sulfonate. SMILES: CC1(C(=[N+](C2=C1C3=CC=CC=C3C=C2)CCCCS(=O)(=O)[O-])C=CC4=C(C(=CC=C5C(C6=C(N5CCCCS(=O)(=O)[O-])C=CC7=CC=CC=C76)(C)C)CCC4)Cl)C.[Na+]. InChI: InChI=1S/C46H51ClN2O6S2.Na/c1-45(2)40(48(28-9-11-30-56(50,51)52)38-24-20-32-14-5-7-18-36(32)42(38)45)26-22-34-16-13-17-35(44(34)47)23-27-41-46(3,4)43-37-19-8-6-15-33(37)21-25-39(43)49(41)29-10-12-31-57(53,54)55;/h5-8,14-15,18-27H,9-13,16-17,28-31H2,1-4H3,(H-,50,51,52,53,54,55);/q;+1/p-1. | |
| New Methylene Blue N | New Methylene Blue N. Group: Biochemicals. Alternative Names: Basic Blue 24; CI 523. Grades: Highly Purified. CAS No. 6586-5-6. Pack Sizes: 10g, 25g. US Biological Life Sciences. | Worldwide |
| New Methylene Blue N ≥90% (Dye content) | New Methylene Blue N ≥90% (Dye content). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g. US Biological Life Sciences. | Worldwide |
| New Methylene Blue N (ZnCl double salt) | 5g Pack Size. Group: Analytical Reagents, Biochemicals, Stains & Indicators. Formula: C18H22ClN3S · 0.5ZnCl2. CAS No. 6586-5-6. Prepack ID 29731030-5g. Molecular Weight 416.05. See USA prepack pricing. |  |
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| New Zealand Chemical Suppliers Database | NZ Chemical Suppliers Database | NZ Chemical Suppliers New Zealand |
| Nexinhib20 | Nexinhib20 is an inhibitor that targets the interactions of Rab27a-JFC1 (IC50: 2.6 μM) and Rac-1-GTP. Nexinhib20 can inhibit neutrophil exocytosis, adhesion, and β2 integrin activation, and has anti-inflammatory activity. Nexinhib20 can be used in the research of diseases such as systemic inflammation and myocardial ischemia-reperfusion injury[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 331949-35-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125792. | |
| Nexturastat A | Nexturastat A is a potent, selective HDAC6 inhibitor. Nexturastat A has inhibitory for HDAC6 with an IC50 of 5 nM. Nexturastat A can be used for the research of multiple myeloma (MM)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1403783-31-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16699. | |
| Nexturastat A (4-((1-butyl-3-phenylureido)methyl)-N-hydroxybenzamide) | Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC50 = 5.02 ± 0.60nm). Displays 600-, 1380-, 1330-, 1870-, -2330, -888, -190, -1340, -1510, and -1020-fold selectivities over HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC7, HDAC8, HDAC9, HDAC10, and HDAC11, respectively. Nexturastat A also displays antiproliferative effects against melanoma cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ne-Z-D-lysine | Ne-Z-D-lysine. Group: Biochemicals. Alternative Names: Nε-Z-D-lysine. Grades: Highly Purified. CAS No. 34404-32-5. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| Ne-Z-D-lysine 98+% (HPLC) | Ne-Z-D-lysine 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Ne-Z-D-lysine benzyl ester hydrochloride | Ne-Z-D-lysine benzyl ester hydrochloride. Group: Biochemicals. Alternative Names: D-Lys(Z)-OBzl·HCl. Grades: Highly Purified. CAS No. 156917-23-6. Pack Sizes: 1g, 2g. US Biological Life Sciences. | Worldwide |
| Ne-Z-D-lysine benzyl ester hydrochloride 99+% (TLC) | Ne-Z-D-lysine benzyl ester hydrochloride 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 2.5g. US Biological Life Sciences. | Worldwide |
| Ne-Z-D-lysine methyl ester hydrochloride | Ne-Z-D-lysine methyl ester hydrochloride. Group: Biochemicals. Alternative Names: D-Lys(Z)-OMe·HCl. Grades: Highly Purified. CAS No. 145586-17-0. Pack Sizes: 2g, 5g, 10g. US Biological Life Sciences. | Worldwide |
| Ne-Z-D-lysine methyl ester hydrochloride 99+% (HPLC) | Ne-Z-D-lysine methyl ester hydrochloride 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 145586-17-0. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Ne-Z-L-lysine 98+% | Ne-Z-L-lysine 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Ne-Z-L-lysine amide hydrochloride | Ne-Z-L-lysine amide hydrochloride. Group: Biochemicals. Alternative Names: L-Lys(Z)-NH2·HCl. Grades: Highly Purified. CAS No. 58117-53-6. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| Ne-Z-L-lysine amide hydrochloride 99+% | Ne-Z-L-lysine amide hydrochloride 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Ne-Z-L-lysine benzyl ester hydrochloride 99+% (HPLC) | Ne-Z-L-lysine benzyl ester hydrochloride 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| Ne-Z-L-lysine methyl ester hydrochloride 98+% (HPLC) | Ne-Z-L-lysine methyl ester hydrochloride 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| Ne-Z-L-lysine tert-butyl ester hydrochloride | Ne-Z-L-lysine tert-butyl ester hydrochloride. Group: Biochemicals. Alternative Names: L-Lys(Z)-OtBu·HCl. Grades: Highly Purified. CAS No. 5978-22-3. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| Ne-Z-L-lysine tert-butyl ester hydrochloride 99+% (TLC) | Ne-Z-L-lysine tert-butyl ester hydrochloride 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Ne-Z-L-lysinol | Ne-Z-L-lysinol. Group: Biochemicals. Alternative Names: L-Lysinol(Z); L-Lys-ol. Grades: Highly Purified. CAS No. 101250-90-2. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences. | Worldwide |
| Ne-Z-L-lysinol ≥95% (HPLC) | Ne-Z-L-lysinol ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Nezutatug | Nezutatug (HMBD-001) is a humanized IgG1 monoclonal antibody inhibitor targeting HER3. Nezutatug inhibits the dimerization of HER3 and inhibits the growth, proliferation and other activities of tumor cells. Nezutatug is promising for research of cancers, such as pancreatic cancer and non-small cell lung cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HMBD-001. CAS No. 2673271-78-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P991237. | |
| NF 023 | NF 023. Group: Biochemicals. Grades: Purified. CAS No. 104869-31-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NF023 hexasodium | NF023 hexasodium is a selective and competitive P2X1 receptor antagonist, with IC50 values of 0.21 μM, 28.9 μM, > 50 μM and > 100 μM for human P2X1, P2X3, P2X2, and P2X4-mediated responses respectively[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 104869-31-0. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg. Product ID: HY-108676. | |
| NF 110 | NF 110. Group: Biochemicals. Grades: Purified. CAS No. 111150-22-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NF157 | NF157 is a highly selective nanomolar P2Y11 antagonist with a pKi of 7.35. The IC50s are 463 nM, 1811 μM, 170 μM for P2Y11 (Ki=44.3 nM), P2Y1 (Ki=187 μM), P2Y2 (Ki=28.9 μM), respectively[1]. NF157, significantly reduces expression of metalloproteinase (MMP)-3, MMP-13, can be used in the treatment of osteoarthritis (OA)[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 104869-26-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-108672. | |
| NF 157 | NF 157. Group: Biochemicals. Grades: Purified. CAS No. 104869-26-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NF279 | NF279 is a selective P2X1 receptor antagonist and NTPDase inhibitor, with a P2X1 IC50 value of 19 nM. NF279 suppresses GABA-evoked currents, reduces ATP-excited respiratory activity, alters hypoglossal nerve burst parameters, and blocks CXCR4, CCR5, CXCR3, and CXCR7-mediated calcium responses. NF279 arrests HIV-1 fusion downstream of CD4 binding, inhibits R5- and X4-tropic HIV-1 strains. NF279 can be used for the research of HIV-1 infection[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 202983-32-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D0976. | |
| NF 279 | NF 279. Group: Biochemicals. Grades: Purified. CAS No. 202983-32-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NF 340 | NF 340. Group: Biochemicals. Grades: Purified. CAS No. 202982-98-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NF449 | NF449. Group: Biochemicals. Alternative Names: 4, 4', 4'', 4'''-[Carbonylbis[imino-5, 1, 3-benzenetriylbis (carbonylimino) ]]tetrakis-1, 3-Benzenedisulfonic Acid Sodium Salt (1:8); 4, 4', 4'', 4'''-[Carbonylbis[imino-5, 1, 3-benzenetriylbis (carbonylimino) ]]tetrakis-1, 3-benzenedisulfonic Acid Octasodium Salt. Grades: Highly Purified. CAS No. 627034-85-9. Pack Sizes: 10mg. Molecular Formula: C41H32N6Na8O29S8, Molecular Weight: 1513.15. US Biological Life Sciences. | Worldwide |
| NF 449 | NF 449. Group: Biochemicals. Grades: Purified. CAS No. 627034-85-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NF449 octasodium | NF449 octasodium is a highly potent P2X1 receptor antagonist, with IC50s of 0.28, 0.69, and 120 nM for rP2X1, rP2X1+5, P2X2+3, respectively. NF449 octasodium is a Gsα-selective G Protein antagonist. NF449 octasodium suppresses the rate of GTP[γS] binding to Gsα-s, inhibits the stimulation of adenylyl cyclase activity, and blocks the coupling of β-adrenergic receptors to Gs[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 627034-85-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112461A. | |
| NF 546 | NF 546. Group: Biochemicals. Grades: Purified. CAS No. 1006028-37-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NF-56-EJ40 | NF-56-EJ40 is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2380230-73-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130246. | |
| NF764 | NF764 is a potent β-catenin (CTNNB1) degrader. NF764 reduces CTNNB1 protein levels in a proteasome-dependent manner. NF764 can be used in the study of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3083634-54-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-161719. | |
| NFAP | NFAP is an antimicrobial peptide found in Neosartorya fischeri (Aspergillus fischeri), and has antifungal activity. Synonyms: Neosartorya (Aspergillus) Fischeri Antifungal Protein. Grade: >98%. | |
| NFAT Inhibitor | A selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Synonyms: H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-OH; L-methionyl-L-alanyl-glycyl-L-prolyl-L-histidyl-L-prolyl-L-valyl-L-isoleucyl-L-valyl-L-isoleucyl-L-threonyl-glycyl-L-prolyl-L-histidyl-L-alpha-glutamyl-L-glutamic acid. Grade: >98%. CAS No. 249537-73-3. Molecular formula: C75H118N20O22S. Mole weight: 1683.93. | |
| NFAT Inhibitor | Selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Does not disrupt other calcineurin-dependent pathways. Inhibits NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells. Group: Biochemicals. Grades: Purified. CAS No. 249537-73-3. Pack Sizes: 1mg. Molecular Formula: C75H118N20O22S, Sequence: MAGPHPVIVITGPHEE. US Biological Life Sciences. | Worldwide |
| NFAT Inhibitor-1 | NFAT Inhibitor (VIVIT peptide) is an inhibitor of nuclear factor of activated Tcells (NFAT) that selectively inhibits calcineurin-mediated dephosphorylation of NFAT[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VIVIT peptide. CAS No. 249537-73-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P1026. | |
| NFAT inhibitor, Cell Permeable | A cell-permeable NFAT inhibitor. It exhibits immunosuppressive effects and can enhance graft survival in mice. Synonyms: 11R-VIVIT; H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Gly-Gly-Gly-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-OH; L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-glycyl-glycyl-glycyl-L-methionyl-L-alanyl-glycyl-L-prolyl-L-histidyl-L-prolyl-L-valyl-L-isoleucyl-L-valyl-L-isoleucyl-L-threonyl-glycyl-L-prolyl-L-histidyl-L-alpha-glutamyl-L-glutamic acid. Grade: >95%. CAS No. 592517-80-1. Molecular formula: C147H259N67O36S. Mole weight: 3573.12. | |
| NFAT Inhibitor, MCV1 (MPB-HPVIVIT, Maleimido-conjugated HPVIVIT, Maleimido-conjugated VIVIT 1) | A cell-permeable, synthetic maleimido-conjugated VIVIT motif peptide (HPVIVIT) that acts as a potent bipartite inhibitor of Nuclear factor of activated T-cells (NFAT) (IC50=62nM). Blocks NFAT-calcineurin interaction by targeting two separate calcineurin docking motifs. Completely blocks NFAT dephosphorylation at 1mM. Determined to be more potent that Cyclosporine A and VIVIT peptide (MAGPHPVIVITGPHEE) in blocking NFAT activity. Also shown to blocks NFAT-mediated T-cell activation and vascular smooth muscle cell proliferation, thereby reducing neoimtima (new thickening of arterial wall) formation in mouse models of restenosis (repeat blocking of blood vessels). The biological half life of MCV1 has been estimated to be about 36 hours in COS-1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C??H??N??O??. US Biological Life Sciences. | Worldwide |
| N-feruloylglycine deacylase | Hydrolyses a range of L-amino acids from the cinnamoyl and substituted cinnamoyl series. Not identical with EC 3.5.1.14 aminoacylase. Group: Enzymes. Synonyms: N-feruloylglycine hydrolase. Enzyme Commission Number: EC 3.5.1.71. CAS No. 118731-84-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4462; N-feruloylglycine deacylase; EC 3.5.1.71; 118731-84-3; N-feruloylglycine hydrolase. Cat No: EXWM-4462. |  |
| N-Feruloyloctopamine | N-Feruloyloctopamine is a natural alkaloid found in the herbs of Datura arborea, it is an tyrosinase inhibitor. N-Feruloyloctopamine has antioxidant activity and can be used in food and medical industry. Uses: Antioxidant. Synonyms: trans-N-Feruloyl octopamine; OctopaMine, N-feruloyl-. Grade: >97%. CAS No. 66648-44-0. Molecular formula: C18H19NO5. Mole weight: 329.35. | |
| N-Feruloyl Serotonin | N-Feruloylserotonin is a conjugated serotonin compound that has been identified as the antioxidative component from the seed of Carthamus tinctorius. N-Feruloylserotonin displayed protective effects on oxidative damage in rat pheochromocytoma cells. Group: Biochemicals. Alternative Names: N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)-2-propenamide; N-Feruloylserotonin; NSC 369502. Grades: Highly Purified. CAS No. 68573-23-9. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| NFF-3 | NFF-3 is a fluorogenic substrate for matrix metalloproteinases (MMPs). NFF-3 is hydrolyzed rapidly by MMP-3 (kcat/Km = 218,000 s-1*M-1) and slowly by MMP-9 (kcat/Km = 10,100 s-1*M-1) with no significant hydrolysis by MMP-1 or MMP-2, therefore it can be used to differentiate MMP-3 activity from that of other MMPs. Synonyms: Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2; ((7-Methoxycoumarin-4-yl)acetyl)arginyl-prolyl-lysyl-prolyl-valyl-glutamyl-norvalyl-tryptophyl-arginyl-(2,4-dinitrophenyl)lysinamide; N2-((7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl)-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-valyl-L-alpha-glutamyl-L-norvalyl-L-tryptophyl-L-arginyl-N6-(2,4-dinitrophenyl)-L-lysinamide; 7-Methoxycoumarin-4-acetyl-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-(2,4-dinitrophenyl)Lysinamide. Grade: ≥95%. CAS No. 158584-09-9. Molecular formula: C78H110N22O20. Mole weight: 1675.84. | |
| NF-κΒ activator 1 | NF-κΒ activator 1 (compound 32) is a potent NF-κΒ activator with an EC50 of 0.9 μM. NF-κΒ activator 1 induces superoxide dismutase (SOD)2 mRNA expression[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2387524-59-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134476. | |
| NF-κB-IN-11 | NF-κB-IN-11 (Compound 3i) is a NF-κB inhibitor. NF-κB-IN-11 inhibits TNF-α induced activation of NF-κB pathway, and inhibits nuclear translocation of NF-κB. NF-κB-IN-11 down-regulates the expression levels of phosphor-IKK, IκBα, and NF-κB p65. NF-κB-IN-11 has anti-inflammatory activity, and alleviates dextran sulfate sodium-induced colitis in mice. NF-κB-IN-11 (p.o.) shows a MTD more than 1852 mg/kg in mice acute toxicity assay[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2768833-35-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155998. | |
| NF-κB-IN-4 | NF-κB-IN-4 (compound 17) is a potent NF-κB pathway inhibitor with blood brain barrier (BBB) permeability. NF-κB-IN-4 exhibits potential anti-neuroinflammatory activity with low toxicity. NF-κB-IN-4 can block the activation and phosphorylation of IκBα, reduce expression of NLRP3, and thus inhibit NF-κB activation. NF-κB-IN-4 can be used for neuroinflammation related diseases research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3033258-60-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144765. | |
| NF-κB p65 Antibody [G23D18] | NFkappaB,NFkappaB Antibody, p65 subunit, active subunit,NF-kB p65,NF-κB p65,RelA / NFkB p65,RELA/NFκB p65. Group: Antibodies. Alternative Names: NFkappaB, p65 subunit, active subunit,NF-kB p65,RELA/NFκB p65. Pack Sizes: 20ul. Product ID: F0006. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| NF-κB Signaling Compound Library | A unique collection of 560 compounds targeting NF-κB signaling for high throughput screening and high content screening; - Effective tool for research in NF-κB signaling and related drug screening; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3800. Categories: NF-κB Signaling Compounds Libraries. |  |
| NF-kB Activation Inhibitor VIII, EVP4593 (SOC Inhibitor, Neuronal Store-Operated Calcium Entry Inhibitor, N4- (4-phenoxyphenethyl) quinazoline-4, 6-diamine, TRPC1 Inhibitor) | A cell-permeable quinazoline derivative that blocks PMA/PHA-induced NF-kB activation in Jurkat cells (IC50=11nM), but has no effect on PKC kinase, and exhibits an anti-inflammatory effect on carrageenin-induced paw edema in rats (1mg/kg, i.p.). In addition, it is shown to inhibit the store-operated calcium entry (SOC) pathway possibly by targeting TRPC1 containing heteromeric channels in Huntington Disease (HD) neurons (SK-N-SH cells transfected with mutant Huntingtin Htt-138Q) at 300nM. It displays neuroprotective effects in YAC128 MSN mice neurons from glutamate toxicity dose-dependently from 30nM to 3uM, which is consistent with TRPC1 knocown effects, and attenuates the progressive decline in the climbing speed of the HD Drosophila, dose-dependently from 100uM to 400uM. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
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