A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
NGD 94-1. Group: Biochemicals. Grades: Purified. CAS No. 178928-68-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NGD 98-2 hydrochloride
NGD 98-2 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NGF-beta from mouse
recombinant, expressed in E. coli, ?98% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
NGF-? from rat
recombinant, expressed in Sf21 cells, lyophilized powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
NGF-? human
from human, recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
Ng-hydroxy-L-arginine. monoacetate
Ng-hydroxy-L-arginine. monoacetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-hydroxy Arginine Acetate; NOHA acetate salt. Appearance: White to off-white solid. CAS No. 53598-01-9. Molecular formula: C8H18N4O5. Mole weight: 250.3. Purity: 98%+. IUPACName: aceticacid;(2S)-2-amino-5-[[amino-(hydroxyamino)methylidene]amino]pentanoicacid. Canonical SMILES: CC(=O)O.C(CC(C(=O)O)N)CN=C(N)NO. Product ID: ACM53598019. Alfa Chemistry ISO 9001:2015 Certified.
NGI-1 (ML414) is a potent oligosaccharyltransferase (OST) inhibitor, directly targeting and blocking the function of the OST catalytic subunits STT3A and STT3B[1]. NGI-1 is a cell permeable inhibitor and can effectively reduce virus infectivity without affecting cell viability[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ML414. CAS No. 790702-57-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117383.
N-GlcNAc-Biotin
N-GlcNAc-Biotin is a groundbreaking compound, primarily renowned for its multifaceted role as a labeling tool. It showcases unrivaled proficiency in elucidating the intricacies of protein-protein interactions and carbohydrate function. Synonyms: 2-Acetamido-N-biotinyl-2-deoxy-b-D-glucopyranosylamine; 2-Acetamido-2-deoxy-b-D-glucopyranosylaminobiotin; N-((2R,3R,4R,5S,6R)-3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide. CAS No. 1272755-69-7. Molecular formula: C18H30N4O7S. Mole weight: 446.52.
N-Glycanase (EDTA-Free) from Elizabethkingia meningoseptica, Recombinant
N-Glycanase (EDTA-Free) from Elizabethkingia meningoseptica, Recombinant. Group: Enzymes. Synonyms: N-Glycanase. Purity: The absence of exoglycosidase contaminants was confirmed by extended incubations with the corresponding pNP or MU-glycosides. No protease activity was detectable after incubation of the enzyme with 0.2 mg resorufin-labeled casein for ~18 hours at 37°C according to the method described by Twining. N-Glycanase. Mole weight: ~35 kDa daltons. Activity: > 10 U/mg. Stability: Extended incubations may be performed at 25°C rather than 37°C to promote stability of the N-Glycanase. Storage: Shipped on ice pack for next day delivery. Store enzyme at 2-8°C or -20°C, but avoid repeated freeze-thawing. Form: A sterile-filtered solution in 20 mM Tris-HCl, 50 mM NaCl (pH 7.5). Source: E. coli. Species: Elizabethkingia meningoseptica. N-Glycanase. Cat No: NATE-0483.
N-Glycidyl Phthalimide
Reagent used for the simultaneous preparation of a primary amine and secondary alcohol. Group: Biochemicals. Alternative Names: 2-(2-Oxiranylmethyl)-1H-isoindole-1,3(2H)-dione; N- (2, 3-Epoxypropyl) phthalimide; 2, 3-Epoxypropyl phthalimide; 2- (Phthalimidomethyl) oxirane; NSC 7244. Grades: Highly Purified. CAS No. 5455-98-1. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
N-Glycolylneuraminic acid
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
N-Glycolylneuraminic acid
N-Glycolylneuraminic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Neu5Gc. Appearance: White to off-white powder. CAS No. 1113-83-3. Molecular formula: C11H19NO10. Mole weight: 325.27. Purity: 0.95. IUPACName: (2S,4S,5R,6R)-2,4-dihydroxy-5-[(2-hydroxyacetyl)amino]-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid. Canonical SMILES: C1[C@@H]([C@H]([C@@H](O[C@@]1(C(=O)O)O)[C@@H]([C@@H](CO)O)O)NC(=O)CO)O. Density: 1.670±0.06 g/ml. Product ID: ACM1113833. Alfa Chemistry ISO 9001:2015 Certified.
N-Glycolylneuraminic acid
N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: NeuGc; GcNeu. CAS No. 1113-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-128965.
N-Glycylproline was found to exhibit anti-ischemic effects on the metabolism of neuroactive amino acids and indices of energy turnover in the neocortex of rats after experimental brain ischemia. Substrate for Prolidase. Group: Biochemicals. Alternative Names: (S) -1- (2-Aminoacetyl) pyrrolidine-2-carboxylic Acid; 1-Glycylproline; 11: PN: CN101988058 SEQID: 11 Claimed Sequence; 12: PN: WO2011133608 TABLE: 5 Claimed Sequence; 132: PN: US20130123467 SEQID: 158 claimed protein; 152: PN: EP2161028 PAGE: 10 Claimed Protein; 2: PN: WO2011150133 PAGE: 63 Claimed Sequence; 7: PN: WO03052099 PAGE: 83 Claimed Protein; 81: PN: WO2011146121 PAGE: 115 Claimed Sequence; Glycyl-L-proline; N-Glycyl-L-proline; NSC 97929. Grades: Purified. CAS No. 704-15-4. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
NGM-120
NGM-120 is a CHO-expressed human antibody that targets GFRAL. NGM-120 contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145.7 kDa. The isotype control for NGM-120 can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2387417-06-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990635.
NG-Monomethyl-L-arginine Acetate (L-NMMA)
A potent inhibitor of NO synthase of adrenal glands, brain, and vascular endothelial cells. Group: Biochemicals. Alternative Names: L-NMMA. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
NG,NG-Dimethy-L-arginine-d6
An arginine derivative; used in chronic kidney diseases.A potential endogenous nitric oxide inhibitor in dialysis. Group: Biochemicals. Alternative Names: N5-[ (Dimethylamino) iminomethyl]-L-ornithine-d6; N5-[Bis (methylamino) methylene]-L-ornithine-d6; SDMA-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
NG,NG-Dimethyl-[d6]-L-arginine dihydrochloride
NG,NG-Dimethyl-[d6]-L-arginine dihydrochloride is a labelled NG,NG-Dimethyl-L-arginine dihydrochloride, which is an endogenous nitric oxide synthase inhibitor. Synonyms: asym-Dimethyl-d6-arginine; ADMA-d6. Grade: 95% by HPLC; 99% atom D. Molecular formula: C8D6H14Cl2N4O2. Mole weight: 281.21.
NG,NG'-Dimethyl-L-arginine ammonium salt
NG,NG'-Dimethyl-L-arginine ammonium salt. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 200mg. US Biological Life Sciences.
Worldwide
NG,NG'-Dimethyl-L-arginine-[d6]
NG,NG'-Dimethyl-L-arginine-[d6] is the labelled analogue of NG,NG'-Dimethyl-L-arginine, which is a potential endogenous nitric oxide inhibitor. Synonyms: NG,NG'-Dimethyl-L-arginine-d6; N5-[(Dimethylamino)iminomethyl]-L-ornithine-d6; N5-[Bis(methylamino)methylene]-L-ornithine-d6; SDMA-d6; N,N'-Dimethylarginine-d6; N(G1),N(G2)-Dimethylarginine-d6; N3,N4-Dimethylarginine-d6. Grade: 96%; ≥99% atom D. CAS No. 1331888-08-4. Molecular formula: C8H12D6N4O2. Mole weight: 208.29.
NG, NG'-Dimethyl-L-Arginine-d6 (Arginine impurity 19). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1331888-08-4. Molecular formula: C8H12N4O2D6. Mole weight: 208.29. Catalog: APB1331888084.
NG,NG-Dimethyl-L-arginine dihydrochloride
A potent inhibitor of NO synthase of adrenal glands, brain, and vascular endothelial cells. NG,NG-Dimethylarginine dihydrochloride is a methylated arginine derivative, which is produced by the liver. It is linked to liver cirrhosis, alcoholic hepatitis and acute liver failure (ALF). Group: Biochemicals. Alternative Names: N5-[ (Dimethylamino) iminomethyl]-L-ornithine Dihydrochloride; ADMA; asym-Dimethylarginine. Grades: Highly Purified. CAS No. 220805-22-1. Pack Sizes: 10mg, 25mg. Molecular Formula: C8H18N4O2·2HCl, Molecular Weight: 275.18. US Biological Life Sciences.
Worldwide
NG,NG'-Dimethyl-L-arginine dihydrochloride
NG,NG'-Dimethyl-L-arginine dihydrochloride. Group: Biochemicals. Alternative Names: SDMA. 2HCl; H-Arg(di-Me)-OH. 2HCl. Grades: Highly Purified. Pack Sizes: 5mg, 10mg, 25mg. US Biological Life Sciences.
Worldwide
NG,NG?-Dimethyl-L-arginine, Dihydrochloride
Cell permeable. Endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity. Group: Fluorescence/luminescence spectroscopy.
NG,NG-Dimethyl-L-arginine, Dihydrochloride - CAS 65005-57-4
A cell-permeable, reversible inhibitor of nitric oxide synthase in vitro (IC?? = 2-3 μM) and in vivo. Group: Fluorescence/luminescence spectroscopy.
NG,NG?-Dimethyl-L-arginine di(p-hydroxyazobenzene-p?-sulfonate) salt
NG,NG'-Dimethyl-L-arginine di(p-hydroxyazobenzene-p'-sulfonate) salt
Plasma sym-dimethylarginine has been considered a marker of hepatic and renal dysfunction. A sensitive LC-MS method for identifying arginine, and both asym- and sym-dimethylarginine in plasma and urine samples has been developed. Group: Biochemicals. Alternative Names: N5-[ (Dimethylamino) iminomethyl]-L-ornithine bis[4-[ (4-hydroxyphenyl) azo]benzenesulfonate]; SDMA. Grades: Highly Purified. CAS No. 1266235-58-8. Pack Sizes: 1mg, 5mg, 10mg, 25mg. Molecular Formula: C8H18N4O2·2C12H10N2O4S , Molecular Weight: 758.82. US Biological Life Sciences.
Worldwide
NG-nitro-L-arginine
NG-nitro-L-arginine (Nω-nitro-L-arginine) is a NO Synthase inhibitor, with K i s of 0.61 μM (nNOS), 4.28 μM (iNOS), 0.72 μM (eNOS) respectively. NG-nitro-L-arginine inhibits endothelium-derived relaxing factor ( EDRF ) formation and release. NG-nitro-L-arginine inhibits portal-systemic shunting in portal-hypertensive rats, and increases blood pressure [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nω-nitro-L-arginine; L-NOARG; L-NG-Nitroarginine. CAS No. 2149-70-4. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-12115.
NG-Nitro-L-arginine Methyl Ester, Hydrochloride - CAS 51298-62-5
Cell permeable. More soluble analog of arginine and a competitive, slowly reversible inhibitor of eNOS (IC?? = 500 nM). Causes a prolonged inhibition of acetylcholine-induced relaxation of rat aortic rings (IC?? = 400 nM). Group: Fluorescence/luminescence spectroscopy.
NGR Peptide 1
It is a peptide with NGR (Asn-Gly-Arg) motif, which has a disulfide bridge linking cys1 to cys5, and is known to have antibacterial properties in addition to the presence of KLA sequences. It binds to CD13 on tumor cells and shows strong cytotoxicity and activity against tumor cells. It can deliver various anti-tumor compounds and virus particles to tumor vessels. Synonyms: H-Cys-Asn-Gly-Arg-Cys-Gly-Gly-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-NH2 (Disulfide bridge: Cys1-Cys5). Grade: ≥95%. CAS No. 1926163-30-5. Molecular formula: C94H174N32O22S2. Mole weight: 2168.75.
NGR Peptide 2
It is a peptide with NGR (Asn-Gly-Arg) motif, which has a disulfide bridge linking cys1 to cys5, and is known to have antibacterial properties in addition to the presence of KLA sequences. It binds to CD13 on tumor cells and shows strong cytotoxicity and activity against tumor cells. It can deliver various anti-tumor compounds and virus particles to tumor vessels. Synonyms: H-Cys-Asn-Gly-Arg-Cys-Gly-Gly-Leu-Val-Thr-Thr-OH (Disulfide bridge: Cys1-Cys5). Grade: >95%. Molecular formula: C41H71N15O15S2. Mole weight: 1078.23.
NGR Peptide 3
It is a peptide with NGR (Asn-Gly-Arg) motif, which has a disulfide bridge linking cys1 to cys5, and is known to have antibacterial properties in addition to the presence of KLA sequences. It binds to CD13 on tumor cells and shows strong cytotoxicity and activity against tumor cells. It can deliver various anti-tumor compounds and virus particles to tumor vessels. Synonyms: H-Cys-Asn-Gly-Arg-Cys-NH2 (Disulfide bridge: Cys1-Cys5). Grade: >95%. Molecular formula: C18H32N10O6S2. Mole weight: 548.64.
NGR peptide Trifluoroacetate
It is recognized by CD13/aminopeptidase N (APN) receptor subtypes, which are selectively overexpressed in tumor neovascularization. Synonyms: NGR peptide TFA; H-Cys-Asn-Gly-Arg-Cys-Gly-OH.TFA; L-cysteinyl-L-asparagyl-glycyl-L-arginyl-L-cysteinyl-glycine trifluoroacetic acid. Grade: >98%. Molecular formula: C20H36N10O8S2.C2HF3O2. Mole weight: 722.72.
Ng-trityl-L-asparagine-2-chlorotrityl resin
Ng-trityl-L-asparagine-2-chlorotrityl resin. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
Ng-Trityl-L-asparagine hydrate
Ng-Trityl-L-asparagine hydrate. Group: Biochemicals. Alternative Names: L-Asn(Trt)-OH·H2O. Grades: Highly Purified. CAS No. 132388-58-0. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Ng-Trityl-L-asparagine hydrate ≥97% (HPLC)
Ng-Trityl-L-asparagine hydrate ≥97% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
N-Guanylurea sulfate
5g Pack Size. Group: Building Blocks, Organics. Formula: C2H8N4O5S. CAS No. 591-01-5. Prepack ID 36862838-5g. Molecular Weight 302.27. See USA prepack pricing.
NGU Guentherin
NGU Guentherin is an antimicrobial peptide found in Rana guentheri (Gunther frog), and has antibacterial activity against gram-positive bacteria S.aureus FDA209P (MIC=35.5 ?/ml) and B.subtilis (MIC≥64 ?/ml). Grade: >98%.
NH125
NH125 is a potent and selective inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K/CaMKIII) , also can induce eEF2 phosphorylation, with an IC 50 of 60 nM for eEF-2K [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 278603-08-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100576.
NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (compound I) hydrochloride is a topoisomerase I inhibitor, which can be delivered to cells through conjugated antibody targeting, and has good ADC activity in vivo and in vitro[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148819A.
NH2-CH2-Bzl-ol-2-chlorotrityl resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: NH2-CH2-Bzl-ol-Trt(2-Cl)-Resin; 4-Aminomethylbenzylalcohol-Trt(2-Cl)-Resin; 4-Aminomethylbenzylalcohol-2-chlorotrityl resin.
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide).
NH2-PEG12-Propionic acid
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Applications may include: bioconjugation, drug delivery, peg hydrogel, crosslinker, and surface functionalization. Group: Poly(ethylene glycol) and poly(ethylene oxide). ≥95%.
NH2-PEG20K-COOH
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: NH2-PEG-COOH. Molecular formula: average Mn 20000.
NH2-PEG20K-COOH
HCl Salt, average Mn 20,000. Group: Poly(ethylene glycol) and poly(ethylene oxide).
NH2-PEG3
NH2-PEG3 (PROTAC Linker 35) is a PROTAC linker, which belongs to a polyethylene glycol (PEG) linker. NH2-PEG3 (PROTAC Linker 35) can be used in the synthesis of the PROTAC (β-NF-JQ1) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PROTAC Linker 35. CAS No. 6338-55-2. Pack Sizes: 1 g; 5 g. Product ID: HY-W007545.
NH2-PEG4-NH2
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide).
NH2-PEG4-Propionic acid
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide).
NH2-PEG5-C2-NH-Boc
NH2-PEG5-C2-NH-Boc (PROTAC Linker 17) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PROTAC Linker 17. CAS No. 189209-27-6. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-W022240.
NH2-PEG8-acid
NH2-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. NH2-PEG8-acid also is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 756526-04-2. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W019798.
NH2-PEG8-NH2
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: S may include: bioconjugation, drug delivery, peg hydrogel, crosslinker, and surface functionalization. Group: Poly(ethylene glycol) and poly(ethylene oxide). Product ID: 2- [2- [2- [2- [2- [2- [2- (2-aminoethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethanamine. Molecular formula: 368.47g/mol. Mole weight: C16H36N2O7. NCCOCCOCCOCCOCCOCCOCCOCCN. InChI= 1S / C16H36N2O7 / c17-1-3-19-5-7-21-9-11-23-13-15-25-16 -14-24-12-10-22-8-6-20-4-2-18 / h1-18H2. MWECBIRKDAZDRL-UHFFFAOYSA-N.
NH2-PEG8-Propionic acid
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide).
NH2-PEG Resin for oligonucleotide synthesis
NH2-PEG Resin for oligonucleotide synthesis. Synonyms: TentaGel N NH2.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: NH2-SAL-Trt(2-Cl)-Resin; Rink amide Barlos Resin; Rink-Bernatowitz-amide Barlos Resin; Knorr-Trt(2-Cl)-Resin.
NH2-UAMC1110 TFA
NH2-UAMC1110 TFA is a UAMC1110 (HY-100684) derivative that can be used in the synthesis of FAPI-QS. UAMC1110 is a fibroblast activation protein (FAP) inhibitor. FAPI-QS is a chelating agent that can be used to synthesize high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2990021-73-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153552A.
NH-3
NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC 50 of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, inhibits binding of thyroid hormones to their receptor and that inhibits cofactor recruitment [1] [2] [3]. NH-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 447415-26-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141513.