A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Nidanilimab (CAN04) is a fully humanized monoclonal anti-IL1RAP antibody with a Kd value of 1.10 pM. Nidanilimab blocks IL1? and IL1? signaling and stimulates the immune system to destroy tumour cells. Nidanilimab can be used in research of non-small lung cancer (NSCLC) and pancreatic ductal adenocarcinoma (PDAC) [1][2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CAN04; Anti-IL-1RAP/IL-1R3 Reference Antibody (nidanilimab). CAS No. 2171061-85-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99379.
Niddamycin
It is a new macrolide antibiotic produced by the strain of Str. rimosus NRRL 3016. Niddamycin is resistant to gram-positive bacteria. Synonyms: 3-Desacetylcarbomycin-B; 9-Deoxy-9-oxoleucomycin V 4B (3-methylbutanoate); F-3463. Grade: ≥98%. CAS No. 20283-69-6. Molecular formula: C40H65NO14. Mole weight: 783.94.
Nidufexor (LMB763) is an orally-available farnesoid X receptor ( FXR ) agonist for the research of nonalcoholic steatohepatitis (NASH) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LMB763. CAS No. 1773489-72-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109096.
Nidulal
Nidulal is originally isolated from Nidula candida 87220. Nidulal induces differentiation of human promyelocytic leukemia cells. In COS-7 cells it selectively activates AP-1 dependent signal transduction in a manner which is similar to TPA/PMA. Synonyms: 4-(8-Methyl-4,7-dioxo-1,6-dioxaspiro[4.4]nona-2,8-dien-3-yl)cyclohexanecarbaldehyde. Grade: 95%. CAS No. 185853-14-9. Molecular formula: C15H16O5. Mole weight: 276.28.
Nidulin
Nidulin is produced by the strain of Asp. nidulans NRRL 2006. It is resistant to mycobacterium but not very effective. Synonyms: Methylustin; O-Methylustin; 4,2-Cresotic acid, 3,5-dichloro-6-(5-chloro-2-hydroxy-4-methoxy-6-(1-methylpropenyl)-m-tolyloxy)-, epsilon-lactone. CAS No. 1329-04-0. Molecular formula: C20H17Cl3O5. Mole weight: 443.70.
Nidulin (Methylustin)
Nidulin is a depsidone produced by several fungal species with potent and selective antibacterial activity. While literature relating to nidulin is limited, it is closely related to folipasatin and unguinol identified as inhibitors of phospholipase A2, arachidonic acid release from rat polymorphonuclear leukocytes and nitrendipine binding to porcine heart membrane. While showing some calcium blocking attributes these metabolites have potential as antiinflammatory agents. Group: Biochemicals. Alternative Names: Methylustin. Grades: Highly Purified. CAS No. 10089-10-8. Pack Sizes: 1mg. US Biological Life Sciences.
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Nifalatide
Nifalatide is a gastrointestinal compound. Synonyms: L-Tyrosyl-S-oxido-D-methionylglycyl-4-nitro-L-phenylalanyl-L-prolinamide. Grade: >98%. CAS No. 73385-60-1. Molecular formula: C30H39N7O9S. Mole weight: 673.74.
NiFe2O4
NiFe2O4. Group: Nanopowder compounds. 98%.
Nifedipine
Nifedipine is a selective calcium channel protein inhibitor. CAS No. 21829-25-4. Product ID: API21829254. SMILES: CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC. Category: Active Pharmaceutical Ingredients.
Nifedipine
Nifedipine. Group: Biochemicals. Grades: Purified. CAS No. 21829-25-4. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Nifedipine
Used as an antihypertensive and antianginal. A dihydorpyridine calcium channel blocker. Synonyms: Nifedipine, Adalat, Procardia, Bay-1040, Cordipin, Corinfar, Bay 1040, Bay1040. Grade: min. 98%. (TLC). CAS No. 21829-25-4. Molecular formula: C17H18N2O6. Mole weight: 346.33.
Nifedipine (BAY-a-1040) is a potent calcium channel blocker and agent of choice for cardiac insufficiencies. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-a-1040. CAS No. 21829-25-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0284.
Nifedipine
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H18N2O6. CAS No. 21829-25-4. Prepack ID 25112948-1g. Molecular Weight 346.33. See USA prepack pricing.
Used as an antihypertensive and antianginal. A dihydorpyridine calcium channel blocker. Group: Biochemicals. Alternative Names: 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid dimethyl Ester, Adalate, Aldipin Anifed, Citilat. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Nifedipine - CAS 21829-25-4
Relatively selective blocker of L-type Ca2+ channels. Group: Fluorescence/luminescence spectroscopy.
Nifedipine-[d4]
Nifedipine-[d4] is labelled Nifedipine which is used as an antihypertensive and antianginal, and is also a dihydorpyridine calcium channel blocker. Synonyms: Nifedipine-d4 (2-nitrophenyl-d4). Grade: 96% by HPLC; 99% atom D. CAS No. 1219798-99-8. Molecular formula: C17H14D4N2O6. Mole weight: 350.36.
Nifedipine-D4
Nifedipine-D4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1219798-99-8. Molecular formula: C17H14D4N2O6. Mole weight: 350.36. Catalog: APB1219798998.
Nifedipine-[d6]
Nifedipine-[d6] is labelled Nifedipine which is used as an antihypertensive and antianginal, and is also a dihydorpyridine calcium channel blocker. Uses: Used as an antihypertensive and antianginal. a labelled dihydorpyridine calcium channel blocker. Synonyms: Nifedipine D6; 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid Dimethyl Ester-d6; Adalate-d6. Grade: 95% by HPLC; 95% atom D. CAS No. 1188266-14-9. Molecular formula: C17H12D6N2O6. Mole weight: 352.37.
Nifedipine-D6
Nifedipine-D6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 125464-52-0. Molecular formula: C17H10D6N2O6. Mole weight: 350.36. Catalog: APB125464520.
Used as an antihypertensive and antianginal. A dihydorpyridine calcium channel blocker. Group: Biochemicals. Alternative Names: 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid dimethyl Ester-d6;Adalate-d6; Aldipin-d6;Anifed-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Nifedipine Impurity 10
Nifedipine Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10323-98-5. Molecular formula: C13H13NO3. Mole weight: 231.25. Catalog: APB10323985.
Nifedipine Impurity 22
Nifedipine Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 167710-84-1. Molecular formula: C17H18N2O5. Mole weight: 330.34. Catalog: APB167710841.
Nifedipine Impurity 6
Nifedipine Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 6-methyl-2,4-bis(2-nitrophenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate. CAS No. 108139-78-2. Molecular formula: C19H18N4O6. Mole weight: 398.12. Catalog: APB108139782.
Nifedipine Nitrophenylpyridine Analog
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Nifedipine Nitrosophenylpyridine Analog
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Nifekalant hydrochloride (MS-551), a class III antiarrhythmic agent, is a IKr potassium channel blocker with an IC 50 of 10 μM. Nifekalant hydrochloride can be used for refractory ventricular tachyarrhythmias research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MS-551. CAS No. 130656-51-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0772A.
Nifekalant Hydrochloride
Nifekalant Hydrochloride is a class III antiarrhythmic agent. Nifekalant Hydrochloride is used in the treatment of patients with extensive anterior infarction and severe ventricular dysfunction. Group: Biochemicals. Alternative Names: 6- [ [2- [ (2-Hydroxyethyl) [3- (4-nitrophenyl) propyl] amino] ethyl] amino] -1, 3-dimethyl-2, 4 (1H, 3H) -pyrimidinedione Hydrochloride; MS 551; Shinbit. Grades: Highly Purified. CAS No. 130656-51-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Nifenalol HCl
Nifenalol, also known as INPEA, is a new beta-adrenergic receptor antagonist. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Nifenalol; Nifenalol HCl; INPEA. Product Category: Antagonists. Appearance: Solid powder. CAS No. 5704-60-9. Molecular formula: C11H17ClN2O3. Mole weight: 260.72. Purity: >98%. IUPACName: 2-(Isopropylamino)-1-(p-nitrophenyl)ethanol hydrochloride. Canonical SMILES: O=[N+](C1=CC=C(C(O)CNC(C)C)C=C1)[O-].[H]Cl. Product ID: ACM5704609. Alfa Chemistry ISO 9001:2015 Certified. Categories: Nifenalol hydrochloride.
Nifenalol hydrochloride
Nifenalol hydrochloride is a β-adrenergic receptor antagonist. Nifenalol hydrochloride induces the Early Afterdepolarization (EAD) effect. EAD is a phenomenon in cardiac electrophysiology that usually occurs during an action potential in ventricular muscle cells and can lead to arrhythmia. The EAD effect of Nifenalol hydrochloride can be blocked by Tetrodotoxin. Nifenalol hydrochloride is used in the study of conditions such as irregular heartbeat or high blood pressure [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5704-60-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100952.
Nifenazone
Nifenazone is a pyrazole agent which can be used in the in the treatment of a variety of rheumatic disorders. Uses: Scientific research. Group: Signaling pathways. CAS No. 2139-47-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17475.
NiFe-type cytoplasmic hydrogenase from Pyrococcus furiosus, recombinant
The [NiFe] hydrogenases contain a minimum of two subunits known as the small (S) and large (L) subunits. The small subunit contains three iron-sulfur clusters while the large subunit contains the active site, a nickel-iron center which is connected to the solvent by a molecular tunnel. To date, periplasmic, cytoplasmic, and membrane-bound hydrogenases have been found. [NiFe] hydrogenases are known to be deactivated by molecular oxygen (O2). The [NiFe] hydrogenase of Pyrococcus furiosus is heterotetrameric wherein the additional two subunits allow the enzyme to use NAD(P)(H) as an electron carrier. Group: Enzymes. Synonyms: Cytoplasmic [NiFe]-Hydrogenase; OE-SHI; Cytoplasmic Hydrogenase; NiFe-type cytoplas. Purity: > 90% by SDS-PAGE. Cytoplasmic hydrogenase. Mole weight: Predicted: 155 kDa, Size Exclusion: 149 kDa +/- 5 kDa. Activity: >100 U/mL. Storage: This item is oxygen sensitive. Stable when stored sealed in strictly anaerobic environment (<10 ppm O2) at room temperature for up to 6 months. For long-term storage, protein can be flash frozen in nitrogen and stored at -80°C. Form: Liquid. Source: Pyrococcus furiosus. Cytoplasmic [NiFe]-Hydrogenase; OE-SHI; Cytoplasmic Hydrogenase; NiFe-type cytoplasmic hydrogenase; SHI; [NiFe] hydrogenase; NADP-specific NiFe-type cytoplasmic hydrogenase. Cat No: NATE-1691.
Niflumic acid
Niflumic acid is a calcium-activated chloride channel blocker and COX -2 inhibitor with the IC 50 value of 100 nM. Niflumic acid induces apoptosis through caspase-8 / Bid / Bax pathway in lung cancer cells. Niflumic acide exhibits anti-tumor activity by affecting the expression of ERK1/2 and the activity of MMP2 and MMP9. Niflumic acid has orally bioactivity. Niflumic acid acts on rheumatoid arthritis [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4394-00-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0493.
Niflumic Acid
Cyclooxygenase-2 (COX-2) inhibitor; GPR35 agonist. Nonsteroidal anti-inflammatory drug (NSAID); selectively inhibits COX-2. Also activates human TRPA1 inducibly expressed in HEK293 cells; displays agonist activity at GPR35. Group: Biochemicals. Alternative Names: 2-[[3- (Trifluoromethyl) phenyl]amino]-3-pyridinecarboxylic Acid; 2-[3- (Trifluoromethyl) anilino]nicotinic Acid; Actol; Actol (analgesic); Donalgin; Flogovital; Forenol; Landruma; Nifluminic Acid; Nifluril; UP 83. Grades: Highly Purified. CAS No. 4394-00-7. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C13H9F3N2O2, Molecular Weight: 282.22. US Biological Life Sciences.
Worldwide
Niflumic acid-[13C6]
Niflumic acid-[13C6] is the labelled analogue of Niflumic Acid, which is a selective COX-2 inhibitor. Synonyms: Niflumic acid-13C6; 2-(3-Trifluoromethylphenyl-13C6-amino)-nicotinic acid; 2-[[3-(Trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic Acid-13C6; 2-[3-(Trifluoromethyl)anilino]nicotinic Acid-13C6; Actol-13C6; Donalgin-13C6; Flogovital-13C6; Forenol-13C6; Landruma-13C6; Nifluminic Acid-13C6; Nifluril-13C6; Niflumic acid-(phenyl-13C6). Grade: 95% by HPLC; 98% atom 13C. CAS No. 1325559-33-8. Molecular formula: C7[13C]6H9F3N2O2. Mole weight: 288.17.
Niflumic Acid-d5 (Major)
Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor. Group: Biochemicals. Alternative Names: 2-[[3- (Trifluoromethyl) phenyl]amino]-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Niflumic acid-(phenyl-13C6)
analytical standard. Group: Opiates / synthetic analgesic drug standards.
Nifuratel
Nifuratel (NF 113) is an orally active broad-spectrum antibiotic with antiprotozoal, antibacterial, anticancer and anti-inflammatory activities, and has good inhibitory effects on Candida and Trichomonas. Nifuratel is also a STAT3 inhibitor, which significantly inhibits the growth and proliferation of human gastric cancer cells and induces apoptosis. In addition, Nifuratel also inhibits mast cell-mediated antigen hypersensitivity reactions and can be used in the study of IgE-mediated allergic diseases [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NF 113; SAP 113; Methylmercadone. CAS No. 4936-47-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0059.
Used as an antibacterial, antifungal, antiprotozoal (Trichomonas). Group: Biochemicals. Alternative Names: 5-[ (Methylthio) methyl]-3-[[ (5-nitro-2-furanyl) methylene]amino]-2-oxazolidinone, Methylmercadone, Inimur, Macmiror, Magmilor, Omnes, Polmiror, Tydantil. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Nifuroxazide
Nifuroxazide is an effective inhibitor of STAT3 , also exerts potent anti-tumor and anti-metastasis activity. Nifuroxazide is an orally active nitrofuran antibiotic. Uses: Scientific research. Group: Signaling pathways. CAS No. 965-52-6. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg. Product ID: HY-B1436.
Nifuroxazide is a cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcription activity with IC50 of 3 μM against IL-6-induced STAT3 activation in U3A cells. It induces apoptosis in breast cancer cells. Uses: Broad-spectrum nitrofuran antibiotic. Synonyms: Nifuroxazid; Dicoferin; Diarlidan; Nifuroxazida; 4-hydroxy-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide. Grade: >98%. CAS No. 965-52-6. Molecular formula: C12H9N3O5. Mole weight: 275.22.
Nifuroxazide-[d4]
Nifuroxazide-[d4] is the labelled analogue of Nifuroxazide. Nifuroxazide is a cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcription activity with IC50 of 3 μM against IL-6-induced STAT3 activation in U3A cells. It induces apoptosis in breast cancer cells. Synonyms: Nifuroxazide D4; 4-Hydroxy-N'-[(E)-(5-nitrofuran-2-yl)methylidene](2H4)benzohydrazide. Grade: 95% by HPLC; 95% atom D. CAS No. 1188487-83-3. Molecular formula: C12H5D4N3O5. Mole weight: 279.24.
Nifurpirinol
analytical standard. Group: Application areaspharma & vet compounds & metabolitespharma & vet compounds & metabolites.
Nifurpirinol
Nifurpirinol (P-7138) is a selective prosubstrate of bacterial nitroreductase (NTR). NTR catalyzes the reduction of nifurpirinol to generate cytotoxic metabolites that induce apoptosis in target cells. Nifurpirinol selectively ablates NTR-expressing cells such as pancreatic ? cells, osteoblasts, dopaminergic neurons, and podocytes in transgenic zebrafish models. Nifurpirinol can be used in regeneration studies and disease modeling such as focal segmental glomerulosclerosis (FSGS)[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: P-7138. CAS No. 13411-16-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135470.
Nifursol
A medicinal, prophylactic additive in animal feeds, protecting poultry from histomoniasis. Group: Biochemicals. Alternative Names: 2-Hydroxy-3,5-dinitro-benzoic Acid 2-[ (5-Nitro-2-furanyl) methylene]hydrazide; 3,5-Dinitro-salicylic Acid (5-Nitrofurfurylidene) hydrazide; Histomon; Salfuride; Sulfuride. Grades: Highly Purified. CAS No. 16915-70-1. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Nifursol
Nifursol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-hydroxy-3,5-dinitro-benzoicaci((5-nitro-2-furanyl)methylene)hydrazide;2-hydroxy-3,5-dinitro-benzoicaci[(5-nitro-2-furanyl)methylene]hydrazide;3,5-dinitrosalicylicacid(5-nitrofurfurylidene)hydrazide;histomon;salicylicacid,3,5-dinitro-(5-nitrofurfurylide. Product Category: Heterocyclic Organic Compound. Appearance: Yellow Solid. CAS No. 16915-70-1. Molecular formula: C12H7N5O9. Mole weight: 365.21. Density: 1.87 g/cm³. Product ID: ACM16915701. Alfa Chemistry ISO 9001:2015 Certified.
Nifursol-[15N2,d2]
Nifursol-[15N2,d2] is the labelled analogue of Nifursol. Nifursol is a nitrofuran antibiotic which inhibits the growth of Histomonas meleagridis. Uses: Labelled nifursol (n458702). a medicinal, prophylactic additive in animal feeds, protecting poultry from histomoniasis. Synonyms: Nifursol 15N2,d2; 2-Hydroxy-3,5-dinitro-N'-{(E)-[5-nitro(2H2)furan-2-yl]methylidene}(15N2)benzohydrazide. Grade: 95% atom D; 95% atom 15N. CAS No. 1246833-64-6. Molecular formula: C12H5D2N3[15N]2O9. Mole weight: 369.21.
Nifursol-15N2,d2
Labeled Nifursol. A medicinal, prophylactic additive in animal feeds, protecting poultry from histomoniasis. Group: Biochemicals. Alternative Names: 2-Hydroxy-3,5-dinitro-benzoic Acid 2-[ (5-Nitro-2-furanyl) methylene]hydrazide-15N2, d2; 3,5-Dinitro-salicylic Acid (5-Nitrofurfurylidene) hydrazide-15N2, d2; Histomon-15N2,d2; Salfuride-15N2,d2; Sulfuride-15N2,d2. Grades: Highly Purified. CAS No. 1246833-64-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Nifurtimox
Antiprotozoal. Showing anti-Trypanosoma cruzi activity. Group: Biochemicals. Alternative Names: 3-Methyl-N-[(5-nitro-2-furanyl)methylene]-. Grades: Highly Purified. CAS No. 23256-30-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Nifurtimox
Nifurtimox, an antiprotozoal agent, which is generally used for the treatment of infections with Trypanosoma cruzi , has been used in the therapy of neuroblastoma. Nifurtimox affects enzyme activity of lactate dehydrogenase ( LDH ). Uses: Scientific research. Group: Signaling pathways. CAS No. 23256-30-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W040073.
Nigericin is an antibiotic derived from Streptomyces hygroscopicus that act as a K + /H + ionophore , promoting K + /H + exchange across mitochondrial membranes. Nigericin is a NLRP3 activator. Nigericin shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt / β-catenin signals. Nigericin induces pyroptosis through caspase 1 /GSDMD in TNBC [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. CAS No. 28380-24-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-127019.
Nigericin
5mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C40H67NaO11. CAS No. 28380-24-7. Prepack ID 50435888-5mg. Molecular Weight 746.94. See USA prepack pricing.
Nigericin
Nigericin, derived from S. hygroscopicus, is an antibiotic potassium ionophore. It exchanges K+ for H+ across biological membranes. Nigericin can be a NLRP3 activator that induces the release of IL-1β as a NALP3-dependent manner. Nigericin triggers eryptosis, an effect paralleled by ROS formation, and in part due to induction of oxidative stress. Nigericin triggers apoptosis. Synonyms: 2-[6-[[2-[5-[5-[6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-7-methoxy-2,4,6-trimethyl-1,10-dioxaspiro[4.5]decan-9-yl]methyl]-3-methyloxan-2-yl]propanoic acid; Antibiotic K178; Antibiotic X464; Azalomycin M; Helexin C, Polyetherin A. Grade: >98%. CAS No. 28380-24-7. Molecular formula: C40H68O11. Mole weight: 724.96.
Nigericin sodium salt is an antibiotic isolated from Streptomyces. It is a cationic ionophore that suppresses growth of gram-positive bacteria. Synonyms: Nigericin Sodium Salt; Nigericin (Sodium Salt); UNII-DGN38HI976; Antibiotic K178. Grade: 95%. CAS No. 28643-80-3. Molecular formula: C40H67NaO11. Mole weight: 746.95.
Nigericin sodium salt
Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus that works by acting as an H+, K+, and Pb2+ ionophore, a NLRP3 activator. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 28643-80-3. Molecular formula: C40H67NaO11. Mole weight: 746.94. Purity: Purity >98%. Product ID: ACM28643803. Alfa Chemistry ISO 9001:2015 Certified.
Nigericin sodium salt
Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus that act as a K + /H + ionophore , promoting K + /H + exchange across mitochondrial membranes. Nigericin sodium salt is a NLRP3 activator. Nigericin sodium salt shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt / β-catenin signals. Nigericin sodium salt induces pyroptosis through caspase 1 /GSDMD in TNBC [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. CAS No. 28643-80-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100381.