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Labeled Nizatidine. Histamine H2-receptor antagonist related to Ranitidine. Antiulcerative. Group: Biochemicals. Alternative Names: N- [2- [ [ [2- [ (Dimethylamino) methyl] -4-thiazolyl] methyl] thio] ethyl] -N- (methyl-d3) -2-nitro-1, 1-ethenediamine; LY-139037-d3; ZE-101-d3; ZL-101-d3; Axid-d3; Calmaxid-d3; Cronizat-d3; Distaxid-d3; Gastrax-d3; Nizax-d3; Nizaxid-d3. Grades: Highly Purified. CAS No. 1246833-99-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Nizatidine-[d3]
Nizatidine-[d3] is the labelled analogue of Nizatidine, which is a histamine H2 receptor antagonist with IC50 of 0. 9 nM, also inhibits AChE with IC50 of 6. 7 μM. Synonyms: Nizatidine D3; N-[2-[[[2-[(Dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N'-(methyl-d3)-2-nitro-1,1-ethenediamine. Grade: 95% by HPLC; 95% atom D. CAS No. 1246833-99-7. Molecular formula: C12H18D3N5O2S2. Mole weight: 334.48.
Nizatidine EP Impurity A
Nizatidine EP Impurity A. Uses: For analytical and research use. CAS No. 54252-45-8. Molecular formula: C4H9N3O2. Mole weight: 131.14. Catalog: APB54252458.
Nizatidine EP Impurity B
Nizatidine EP Impurity B. Uses: For analytical and research use. CAS No. 61832-41-5. Molecular formula: C4H8N2O2S. Mole weight: 148.18. Catalog: APB61832415.
Nizatidine EP Impurity D
Nizatidine EP Impurity D. Uses: For analytical and research use. CAS No. 78441-62-0. Molecular formula: C9H17N3S2. Mole weight: 231.38. Catalog: APB78441620.
Nizatidine EP Impurity E
Nizatidine EP Impurity E. Uses: For analytical and research use. CAS No. 188666-11-7. Molecular formula: C11H18N4O3S2. Mole weight: 318.41. Catalog: APB188666117.
Nizatidine EP Impurity F
Nizatidine EP Impurity F. Uses: For analytical and research use. CAS No. 1193434-62-6. Molecular formula: C15H25N7O4S3. Mole weight: 463.59. Catalog: APB1193434626.
Nizatidine EP Impurity G
Nizatidine EP Impurity G. Uses: For analytical and research use. CAS No. 1193434-63-7. Molecular formula: C20H33N7O2S4. Mole weight: 531.77. Catalog: APB1193434637.
Nizatidine EP Impurity H
Nizatidine EP Impurity H. Uses: For analytical and research use. CAS No. 27366-72-9. Molecular formula: C4H11ClN2S. Mole weight: 154.66. Catalog: APB27366729.
Nizatidine EP Impurity I
Nizatidine EP Impurity I. Uses: For analytical and research use. CAS No. 82586-81-0. Molecular formula: C11H20N4OS2. Mole weight: 288.43. Catalog: APB82586810.
Nizatidine EP Impurity J
Nizatidine EP Impurity J. Uses: For analytical and research use. CAS No. 78441-69-7. Molecular formula: C7H12N2OS. Mole weight: 172.25. Catalog: APB78441697.
Nizatidine impurity 1
Nizatidine impurity 1. Uses: For analytical and research use. CAS No. 92759-37-0. Molecular formula: C7H13ClN2OS. Mole weight: 208.7. Catalog: APB92759370.
Histamine H2-receptor antagonist related to ranitidine. Group: Biochemicals. Alternative Names: N- [2- [ [ [2- [ (Dimethylamino) methyl] -4-thiazolyl] methyl] thio] ethyl] -N-methyl-2-nitro-1, 1-ethenediamine; LY-139037; ZE-101; ZL-101; Axid; Calmaxid; Cronizat; Distaxid; Gastrax; Nizax; Nizaxid. Grades: Highly Purified. CAS No. 76963-41-2. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Nizatidine Sulfoxide-[d3]
Nizatidine Sulfoxide-[d3] is the labelled analogue of Nizatidine Sulfoxide, which is an impurity of Nizatidine. Nizatidine is a histamine H2 receptor antagonist. Synonyms: Nizatidine-d3 Sulfoxide; N-[2-[[[2-[(Dimethylamino)methyl]-4-thiazolyl]methyl]sulfinyl]ethyl]-N'-(methyl-d3)-2-nitro-1,1-ethenediamine; Nizatidine EP Impurity C-d3. CAS No. 1795136-43-4. Molecular formula: C12H18D3N5O3S2. Mole weight: 350.48.
Ni-Zn Alloy Powder
Ni-Zn Alloy Powder. Purity: 99.7%+.
Nizofenone fumarate
Nizofenone fumarate. Group: Biochemicals. Grades: Highly Purified. CAS No. 54533-86-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences.
Worldwide
N-[(+)-Jasmonoyl]-(L)-isoleucine
N-[(+)-Jasmonoyl]-(L)-isoleucine has been used in synthetic preparation of isoleucine conjugate of epi-jasmonic acid. Synonyms: JA-L-Ile; N-[(1S,2S)-3-oxo-2-(2-(Z)-pentenyl)cyclopentane-1-acetyl]-isoleucine. CAS No. 120330-92-9. Molecular formula: C18H29NO4. Mole weight: 323.43.
NJH-2-030
NJH-2-030 can be used as a covalent recruiter for FEM1B in targeted protein degradation applications. Uses: Scientific research. Category: Signaling pathways. CAS No. 2709040-02-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143348.
NJH-2-057
NJH-2-057 is an EN523 OTUB1 recruiter linked to lumacaftor, a agent used to treat cystic fibrosis that binds ΔF508-CFTR. Uses: Scientific research. Category: Signaling pathways. CAS No. 2858812-70-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115878.
NK 1001
NK 1001 is produced by the strain of Streptomyces kanamyceticus var. NK 1001 has weak activity against gram-positive, gram-negative and mycobacterium bacteria. Synonyms: Antibiotic NK 1001; 4,6-Diamino-3-(hexopyranosyloxy)-2-hydroxycyclohexyl 6-amino-6-deoxyhexopyranoside. CAS No. 53025-93-7. Molecular formula: C18H35N3O12. Mole weight: 485.48.
NK-1013-1
NK-1013-1 is an aminoglycoside antibiotic isolated from Streptomyces kanamyceticus var.21-16. It is active against gram-positive bacteria. Synonyms: Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-4)-O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-N(sup 3)-acetyl-, D-. CAS No. 102612-61-3. Molecular formula: C20H38N4O13. Mole weight: 542.5.
NK-1013-2
NK-1013-2 is an aminoglycoside antibiotic isolated from Streptomyces kanamyceticus var.21-16. It is active against gram-positive and gram-negative bacteria. Molecular formula: C22H40N4O14. Mole weight: 584.6.
NK10958P
NK10958P is a plant growth regulator produced by Streptomyces sp. NK10958. Synonyms: NK-10958P. Molecular formula: C18H30O4. Mole weight: 310.4.
NK 154183A
NK 154183A is a 24-membered macrolide antibiotic isolated from the fermentation broth of Streptomyces sp. NK154183. It exhibits antifungal and antitumor activity against the human colon adenocarcinoma. Synonyms: NK154183A; (4E,18E)-11,12,13,14,16,17,27a-Heptahydroxy-6'-(2-hydroxybutyl)-2,2,11,15,17,28-hexamethyl-2,3,3',3a,4',5',6,6',7,8,9,10,11,12,13,14,15,16,17,22,23,26,27,27a-tetracosahydro-20H-spiro[22,26-methanofuro[2,3-h][1,5]dioxacyclohexacosine-24,2'-pyran]-20-one. CAS No. 152986-47-5. Molecular formula: C41H70O13. Mole weight: 771.
NK 154183B
NK 154183B is a 24-membered macrolide antibiotic isolated from the fermentation broth of Streptomyces sp. NK154183. It exhibits antifungal and antitumor activity against the human colon adenocarcinoma. Synonyms: NK154183B; (4E,18E)-13-{[5-(Dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl]oxy}-11,12,14,16,17,27a-hexahydroxy-6'-(2-hydroxybutyl)-2,2,11,15,17,28-hexamethyl-2,3,3',3a,4',5',6,6',7,8,9,10,11,12,13,14,15,16,17,22,23,26,27,27a-tetracosahydro-20H-spiro[22,26-methanofuro[2,3-h][1,5]dioxacyclohexacosine-24,2'-pyran]-20-one. CAS No. 152986-49-7. Molecular formula: C49H85NO14. Mole weight: 912.2.
NK 252
NK 252. Group: Biochemicals. Grades: Purified. CAS No. 1414963-82-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NK-252
NK-252 is a potential Nrf2 activator, which exhibits a great Nrf2-activating potential. Uses: Scientific research. Category: Signaling pathways. CAS No. 1414963-82-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19734.
NK30424A
NK30424A is an inhibitor of lipopolysaccharide-induced tumour necrosis factor alpha production with IC50 value of 1 μmol/L. It is produced by Streptomyces sp. NA30424. Molecular formula: C30H46N2O10S. Mole weight: 626.8.
NK30424B
NK30424B is an inhibitor of lipopolysaccharide-induced tumour necrosis factor alpha production with IC50 value of 0.9 μmol/L. It is produced by Streptomyces sp. NA30424. Molecular formula: C30H46N2O10S. Mole weight: 626.8.
NK374200
NK374200 is an insecticidal agent produced by Taralomyces. Molecular formula: C12H17N7O3. Mole weight: 307.31.
Nk-611 hydrochloride
Nk-611 hydrochloride. CAS No. 105760-98-3. Product ID: ACM105760983. Molecular formula: C31H37NO12.HCl. Mole weight: 652.08. Alfa Chemistry - ISO 9001:32057 Certified.
N-(Ketocaproyl)-D,L-homoserine lactone
N-(Ketocaproyl)-D,L-homoserine lactone. Group: Biochemicals. Grades: Highly Purified. CAS No. 76924-95-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C10H15NO4. US Biological Life Sciences.
Worldwide
N-(Ketocaproyl)-DL-homoserine lactone
N-(Ketocaproyl)-DL-homoserine lactone is a natural, very active ligand of LuxR. N-(Ketocaproyl)-DL-homoserine lactone is a quorum sensing (QS) autoinducer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 76924-95-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129405.
N-(Ketocaproyl)-L-homoserine lactone
N-(Ketocaproyl)-L-homoserine lactone. Group: Biochemicals. Alternative Names: N-(3-Oxohexanoyl)-homoserine lactone; (S)-3-Oxo-N-(tetrahydro-2-oxo-3-furanyl)hexanamide. Grades: Highly Purified. CAS No. 143537-62-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C10H15NO4. US Biological Life Sciences.
An autoinducer of P. fischeri luciferase. A specfic genetic regulator that is unrelated to at least one of the enzyme systems that it induces, and it acts after excretion and accumulation in the extracellular medium. Group: Biochemicals. Alternative Names: N-(3-Oxohexanoyl)-homoserine Lactone. Grades: Highly Purified. CAS No. 143537-62-6. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
NKH477
NKH477 (Colforsin dapropate hydrochloride) directly activates the catalytic unit of adenylate cyclase and increases intracellular cAMP. NKH477 is a forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 exerts an antiproliferative effect in vivo with an altered cytokine profile to inhibit the acute rejection of rat orthotopic lung allografts[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Colforsin dapropate hydrochloride. CAS No. 138605-00-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103193.
NKH 477
NKH 477 is a water-soluble analog of Forskolin, that is a potent activator of adenylyl cyclase, which shows some selectivity for cardiac (type V) adenylyl cyclase). Group: Biochemicals. Alternative Names: N,N-Dimethyl- β-alanine (3R, 4aR, 5S, 6S, 6aS, 10S, 10aR, 10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-10, 10b-dihydroxy-3, 4a, 7, 7, 10a-pentamethyl-1-oxo-1H-naphtho[2, 1-b]pyran-6-yl Ester HCl; N,N-Dimethyl- β-alanine [3R-(3α,4a β,5 β,6 β, 6aα, 10α, 10a β,10bα)]-5-(Acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl Ester HCl; 1H-Naphtho[2,1-b]pyran, β-alanine deriv.; 6- (3-Di methyl aminopropionyl) forskolin HCl; Adehl; Colforsin Dapropate HCl. Grades: Highly Purified. CAS No. 138605-00-2. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C??H??ClNO?, Molecular Weight: 546.09. US Biological Life Sciences.
Worldwide
NKY80
NKY80 is a potent, selective and non-competitive adenylyl cyclase (AC) type V isoform inhibitor with IC50s of 8.3 μM, 132 μM and 1.7 mM for type V, III and II, respectively. NKY80 is a non-nucleoside quinazolinone and regulates the AC catalytic activity in heart and lung tissues[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 299442-43-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103195.
NKY 80
NKY 80. Group: Biochemicals. Grades: Purified. CAS No. 299442-43-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NL-1
NL-1 is a mitoNEET inhibitor with antileukemic effect. NL-1 inhibits REH and REH/Ara-C cells growth with IC50s of 47.35 μM and 56.26 μM, respectively. NL-1-mediated death in leukemic cells requires the activation of the autophagic pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 188532-26-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-135231.
NL3
NL3 is a bacterial cystathionine γ-lyase inhibitor, with IC50s of 0.7 μM (bCSE) and 3.4 μM (hCSE) respectively. NL3 can be used for antimicrobial and circumventing bacterial resistance research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2395867-03-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-170028.
N-Lactoyl-phenylalanine
N-Lactoyl-phenylalanine is a blood-derived signaling metabolite that can be induced by exercise. N-Lactoyl-phenylalanine can reduce obesity and improve glucose tolerance[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lac-Phe. CAS No. 183241-73-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150012.
N-Lactylleucine
N-Lactylleucine is an endogenous metabolite that can be identified in patients with the intermediate type of maple syrup urine disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 112757-17-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164805.
N-LAUROYLSARCOSINE
N-LAUROYLSARCOSINE. Synonyms: n-methyl-n-(1-oxododecyl)-glycin;N-methyl-N-(1-oxododecyl)-Glycine;N-LAUROYLSARCOSINE FREE ACID;N-acyl sarcosinate;Glycine, N-methyl-N-(1-oxododecyl)-;n-lauroylsarcosine,neat;N-Lauroylsarkosin;N-Dodecanoyl-N-methylglycine, Sarkosyl L. CAS No. 97-78-9. Pack Sizes: 1 kg. Product ID: CDF4-0094. Molecular formula: C15H29NO3. Category: Food Emulsifiers. Product Keywords: Food Ingredients; Food Emulsifiers; N-LAUROYLSARCOSINE; CDF4-0094; 97-78-9; C15H29NO3; 202-608-3; 97-78-9. Purity: 0.99. Color: White or Colorless to Almost White or Almost colorless. EC Number: 202-608-3. Physical State: Powder to lump to Clear Liquid. Solubility: almost transparency in Methanol. Application: N-Lauroylsarcosine may be used as a permeation enhancer in the transdermal drug delivery formulations since it increases the fluidity of stratum corneum lipid structure of the skin. Boiling Point: 413.2±28.0 °C(Predicted). Melting Point: 45-49 °C. Product Description: N-Lauroylsarcosine is an anionic surfactant with an ability to denature proteins. Due to its microbicidal property, N-lauroylsarcosine is being considered as a potent anti-microbicide in topical formulations,?especially against sexually transmitted diseases (STDs).
N-Lauroylsarcosine sodium salt
500g Pack Size. Group: Amino Acids, Biochemicals. Formula: C15H28NNaO3. CAS No. 137-16-6. Prepack ID 12615111-500g. Molecular Weight 293.38. See USA prepack pricing.
N-Lauroylsarcosine sodium salt
N-Lauroylsarcosine sodium salt. CAS No. 137-16-6. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
N-L-γ-glutamyl-L-tyrosine is a dipeptide produced by the catabolism of proteins. Synonyms: Gamma-Glutamyltyrosine; H-gamma-Glu-Tyr-OH; H-Glu(Tyr-OH)-OH. Grade: ≥95%. CAS No. 7432-23-7. Molecular formula: C14H18N2O6. Mole weight: 310.31.
N-lignoceroyl-D-erythro-sphingosine
N-lignoceroyl-D-erythro-sphingosine. Group: Biochemicals. Grades: Highly Purified. CAS No. 102917-80-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C42H83NO3. US Biological Life Sciences.
Worldwide
N-L-Lysyl-L-glutamic acid
N-L-Lysyl-L-glutamic acid. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg. US Biological Life Sciences.
Worldwide
N-L-Lysyl-L-glutamic acid
N-L-Lysyl-L-glutamic acid is a dipeptide composed of L-lysine and L-glutamic acid. L-lysine is an essential amino acid important for protein synthesis, tissue repair, and enzyme function, while L-glutamic acid is a non-essential amino acid that serves as a neurotransmitter and plays a role in cellular metabolism. This dipeptide may be studied for its impact on protein interactions, metabolic pathways, or neurochemistry, and could be used in research related to peptide synthesis, enzyme activity, and amino acid effects on biological systems. Synonyms: KE; Lysylglutamic acid; Lys-Glu; Lys-Glu-OH; Lys Glu OH; H-Lys-Glu-OH; H-KE-OH; Vilon; Vilon (peptide); (S)-2-((S)-2,6-Diaminohexanamido)pentanedioic acid; L-Lys-L-Glu; KE dipeptide; Lysine Glutamate dipeptide. Grade: ≥95%. CAS No. 45234-02-4. Molecular formula: C11H21N3O5. Mole weight: 275.30.
N-(long-chain-acyl)ethanolamine deacylase
Does not act on N-acylsphingosine or N,O-diacylethanolamine. Group: Enzymes. Synonyms: N-acylethanolamine amidohydrolase; acylethanolamine amidase. Enzyme Commission Number: EC 3.5.1.60. CAS No. 99283-61-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4450; N-(long-chain-acyl)ethanolamine deacylase; EC 3.5.1.60; 99283-61-1; N-acylethanolamine amidohydrolase; acylethanolamine amidase. Cat No: EXWM-4450.
N-Losartanyl-losartan
N-Losartanyl-losartan
Sarchem Laboratories New Jersey NJ
NLP-28
NLP-28 is an antimicrobial peptide found in Caenorhabditis elegans, and has antifungal activity. Synonyms: Neuropeptide-like protein 28. Grade: >85%.
NLP-31
NLP-31 is an antimicrobial peptide found in Caenorhabditis elegans, and has antifungal activity against D.coniospora. It has weak antibacterial activity against gram-positive bacteria M.luteus and gram-negative E.coli. Synonyms: Neuropeptide-like protein 31. Grade: >85%.
N-(L-Prolyl)- β-alanine
N-(L-Prolyl)- β-alanine is a derivative of β-Alanine (A637320); a naturally occurring beta amino acid that is formed in vivo by the degradation of Dihydro Uracil (D449990) and Carnosine (C184190). β-Alanine is also the rate-limiting precursor of Carnosine, as a result supplementation with β-alanine increases the concentration of Carnosine in muscles. Group: Biochemicals. Grades: Highly Purified. CAS No. 112558-45-9. Pack Sizes: 100mg, 1g. Molecular Formula: C8H14N2O3, Molecular Weight: 186.21. US Biological Life Sciences.
Worldwide
N-L-Prolyl-L-histidine
Prolyl-histidine is a dipeptide composed of proline and histidine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: H-Pro-His-OH; H-PH-OH; L-prolyl-L-histidine; Prolyl-Histidine; L-Histidine, L-prolyl-; (S)-3-(1H-Imidazol-4-yl)-2-((S)-pyrrolidine-2-carboxamido)propanoic acid; N-prolyl histidine. Grade: ≥95%. CAS No. 92027-43-5. Molecular formula: C11H16N4O3. Mole weight: 252.27.
NLRP3/AIM2-IN-3
NLRP3/AIM2-IN-3 (compound 59) is a potent inhibitor with differential species specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. NLRP3/AIM2-IN-3 shows inhibitory efficacy against pyroptosis in THP-1 macrophages stimulated with LPS/nigericin, with an IC50 of 0.077 ± 0.008 μM. NLRP3/AIM2-IN-3 disturbs the interaction of NLRP3 or AIM2 with the adaptor protein ASC and inhibited ASC oligomerization[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1787787-60-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144226.
NLRP3 Antibody [E13F14]
Cryopyrin/NALP3/NLRP3,NLRP3,NLRP3/NALP3. Group: Antibodies. Alternative Names: Cryopyrin/NALP3/NLRP3,NLRP3,NLRP3/NALP3. Pack Sizes: 20ul. Product ID: F0335. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
NLRP3 Antibody [E14M24]
NLRP3 Antibody [E14M24]. Group: Antibodies. Alternative Names: NACHT, LRR and PYD domains-containing protein 3; Angiotensin / vasopressin receptor AII/AVP-like; Caterpiller protein 1.1; Cold-induced autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1; NLRP3; C1orf7; CIAS1; NALP3; PYPAF1. Pack Sizes: 20uL. Product ID: F4415. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
NLRP3 Antibody [K12J9]
Cryopyrin/NALP3/NLRP3,NLRP3,NLRP3/NALP3. Group: Antibodies. Alternative Names: Cryopyrin/NALP3/NLRP3,NLRP3,NLRP3/NALP3. Pack Sizes: 20uL. Product ID: F3229. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
NLRP3-IN-13
NLRP3-IN-13 (Compound C77 in reference patent) is a selective and potent NLRP3 inhibitor (IC50: 2.1 μM). NLRP3-IN-13 inhibits NLRP3 andNLRC4 inflammasomes, and inhibits NLRP3-mediated IL-1β production. NLRP3-IN-13 also inhibits NLRP3 ATPase activity. NLRP3-IN-13 can be used in the research of neuroinflammatory disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1704638-35-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150206.
NLRP3-IN-17
NLRP3-IN-17 is a potent, selective and orally active NLRP3 inflammasome inhibitor with an IC50 value of 7 nM. NLRP3-IN-17 significantly inhibits NLRP3 dependent IL-1β secretion in mice and can be used for chronic inflammatory diseases research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2254432-75-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153261.
NLRP3-IN-25
NLRP3-IN-25 (compound 32) is an orally available NLRP3 inhibitor with anti-inflammatory activity. NLRP3-IN-25 attenuates renal injury in doxorubicin-induced glomerulonephritis in mice. NLRP3-IN-25 inhibits IL-1β secretion in THP-1 cells with an IC50 of 21 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2660230-90-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155463.
NLS-Cas9-D10A Nickase
NLS-Cas9-D10A Nickase. Nls-cas9-d10a nickase is a mutation form of cas9 nuclease which makes one active domain deactivated, thus it can only cut one single strand dna that is complementary to the guide-rna, producing one single strand cut. combined with two different grna, nls-cas9-d10a nickase produces two cut sites respectively and causes a double strand break. compared with the wild type cas9 nuclease, the two-grna guided cleavage can significantly reduce the off target effects. Group: Cloning Enzymes. Purity: 10μg; 50μg. Storage: Store at -20 ?. Source: E.coli. Pack: 10 mM Tris, 300 mM NaCl, 0.1 mM EDTA, 1 mM DTT, 50% Glycerol pH7.4 at 25 °C. Cat No: CE-3505.
NLS-Cas9-EGFP Nuclease
NLS-Cas9-EGFP Nuclease. Nls-cas9-egfp is a fusion protein contains a nuclear localization sequence (nls) on its n terminal and egfp on the c terminal. the egfp can be used as a reporter for tracking or sorting transfected cells, which enables the possibility of enriching cell populations for desired genome edits via fluorescence activated cell sorting (facs). it significantly reduces the labor and cost associated with single cell cloning and genotyping in genome editing applications. Group: Cloning Enzymes. Purity: 100μg; 500μg. Storage: Store at -20 ?. Source: E.coli. Pack: 10 mM Tris, 300 mM NaCl, 0.1 mM EDTA,1 mM DTT, 50% Glycerol PH7.4, at 25°C. Cat No: CE-3506.
NLS-Cas9-NLS Nuclease
NLS-Cas9-NLS Nuclease. Nls-cas9-nls is produced by expression in an e. coli strain carrying a plasmid encoding the cas9 gene from streptococcus pyogenes with a double-ends nuclear localization signal (nls). it can be used for genome editing by inducing site-specific dna double stranded breaks. cas9 protein forms a very stable ribonucleoprotein (rnp) complex with the guide rna (grna) component of the crispr/cas9 system, which can localize to the nucleus immediately once entering the cell with the guide of the nls. compared with the mrna or plasmid systems, transcription and translation processes are not required. this dna-free system avoids the risk of inserting foreign dna into the genome, which can be quite useful for gene editing-based disease therapy. our highly pure and active cas9 nuclease meets all of the researcher´s requirements (e.g. in vitro cleavage assay, rnp complex transfection, micro injection). Group: Cloning Enzymes. Purity: 50μg; 100μg. Storage: Store at -20 ?. Source: E.coli. Pack: 10 mM Tris, 300 mM NaCl, 0.1 mM EDTA, 1 mM DTT, 50% Glycerol pH7.4 at 25?. Cat No: CE-3504.
NLS (PKKKRKV)
NLS (PKKKRKV) is a nuclear localization signal (NLS) derived from the SV40 large T antigen, which mediates the binding of karyophilic proteins to importin α. NLS (PKKKRKV) serves as a method to enhance nuclear entry in the field of gene transfer research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 95088-49-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1876.