A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
A useful disulfide cleavable linking reagent. Group: Biochemicals. Alternative Names: Boc-Aoa-NH-(CH2)2-S-S-Pyr. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
NS309
NS309 is a potent and selective activator of the Ca2+-activated SK/IK potassium channels, but displays no activity at BK channels[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18711-16-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15416.
NS 309
NS 309. Group: Biochemicals. Grades: Purified. CAS No. 18711-16-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NS3623
NS3623 is an activator of human ether-a-go-go-related gene (hERG1/KV11.1) potassium channels. NS3623 activates the IKr and Ito currents and has antiarrhythmic effect. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 343630-41-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108586.
NS 3623
NS 3623. Group: Biochemicals. Alternative Names: 1-(3-Trifluoromethylphenyl)-3-[2-(1H-tetrazol-5-yl)-4-bromophenyl]urea; N-[4-Bromo-2- (2H-tetrazol-5-yl) phenyl]-N'-[3- (trifluoromethyl) phenyl]-urea. Grades: Highly Purified. CAS No. 343630-41-1. Pack Sizes: 10mg. Molecular Formula: C15H10BrF3N6O, Molecular Weight: 427.18. US Biological Life Sciences.
Worldwide
NS3694
NS3694, a diarylurea compound, is an apoptosome inhibitor. NS3694 inhibits apoptosome formation and caspase activation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 426834-38-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108356.
NS 3763
NS 3763. Group: Biochemicals. Grades: Purified. CAS No. 70553-45-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NS 398
NS 398. Group: Biochemicals. Grades: Purified. CAS No. 123653-11-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NS-398
NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 123653-11-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13913.
NS-398 (NS398, NS 398)
NS-398 (NS398, NS 398). Group: Biochemicals. Alternative Names: N- (2-cyclohexyloxy-4-nitrophenyl) methanesulfonamide. Grades: Highly Purified. CAS No. 123653-11-2. Pack Sizes: 50mg. Molecular Formula: C13 H18 N2O5, Molecular Weight: 314.4. US Biological Life Sciences.
Worldwide
NS-5
NS-5 is a beta-lactam antibiotic produced by Streptomyces cattaleya. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Molecular formula: C11H16N2O3S. Mole weight: 256.32.
NS5806
NS5806, a potent potassium current activator, increases KV4.3/KChIP2 peak current amplitudes with an EC50 of 5.3 μM. NS5806 slows KV4.3 and KV4.2 current dacay in channel complexes containing KChIP2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 426834-69-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-108588.
NS 5806
NS 5806. Group: Biochemicals. Grades: Purified. CAS No. 426834-69-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NS 6180
NS 6180. Group: Biochemicals. Grades: Purified. CAS No. 353262-04-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NS8593 hydrochloride
NS8593 hydrochloride is a potent and selective small conductance Ca2+-activated K+ channels (SK channels) inhibitor. NS8593 hydrochloride reversibly inhibits SK3-mediated currents with a Kd value of 77 nM. NS8593 hydrochloride inhibits all the SK1-3 subtypes Ca2+-dependently (Kds of 0.42, 0.60, and 0.73 μM, respectively, at 0.5 μM Ca2+), and does not affect the Ca2+-activated K+ channels of intermediate and large conductance (hIK and hBK channels, respectively)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 875755-24-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-110105.
An aminobenzimidazole derivative that selectively and reversibly blocks small conductance Ca2+-activated K+ channels (SK1-3; =420nM, 600nM, and 730nM for SK1, SK2, SK3, respectively) in a Ca2+-dependent manner. It mediates channel gating by interacting with gating structures deep within the inner pore vestibule where Ser507 and Ala532 are deemed to be important for inhibition. Interacts at a site that is distinct from the apamin binding site in SK channels. Can access high-affinity binding sites from both the inside and outside of the cell membrane. Does not affect QT intervals, but prolongs the atrial effective refractive period and prevents acetylcholine-induced atrial fibrillations in ex vivo and in vivo models. Also shown to reversibly block TRPM7 channel (IC50=1.6mM) in smooth muscle cells, primary podocytes, HEK293 cells expressing TRPM7, and ventricular myocytes in a Mg2+-dependent manner and blocks the motility of cells in culture. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
NS 9283
NS 9283. Group: Biochemicals. Grades: Purified. CAS No. 913830-15-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
N-Salicylideneaniline
N-Salicylideneaniline. Group: Biochemicals. Alternative Names: N-Salicylalaniline. Grades: Highly Purified. CAS No. 779-84-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences.
Worldwide
N,S-Bis-Fmoc-Glutathione
N,S-Bis-Fmoc-Glutathione is a potent glyoxalase II inhibitor with a Ki value of 0.75 μM and an IC50 of 2.5 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 149438-56-2. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-P4277.
NSC 109555
NSC 109555. Group: Biochemicals. Alternative Names: 4,4'-Diacetyldiphenylurea bis(guanylhydrazone) Bismethanesulfonate; 2, 2'- [Carbonyl bis (imino-4, 1-phenyl ene ethyl idyne ) ] bis-hydrazinecarboximidam ide Dimethanesulfonate. Grades: Highly Purified. CAS No. 15427-93-7. Pack Sizes: 10mg. Molecular Formula: C21H32N10O7S2, Molecular Weight: 600.669999999999. US Biological Life Sciences.
Worldwide
NSC 109555 ditosylate
NSC 109555 ditosylate. Group: Biochemicals. Grades: Purified. CAS No. 66748-43-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NSC117079
NSC117079 is a novel PHLPP inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 500363-63-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19819.
NSC139021 (ERGi-USU) is a RIOK2 inhibitor with anticancer activity. RIOK2 can highly selectively inhibit the growth of ERG-positive cancer cells with IC50s of 30-400 nM against cell lines. RIOK2 also causes cell cycle arrest and apoptosis in glioblastoma via induction of Skp2 and Skp2-p27/p21-Cyclin E/CDK2-pRb signaling[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ERGi-USU. CAS No. 1147-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-112158.
NSC 146109 hydrochloride
NSC 146109 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 59474-01-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NSC 15364
NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4550-72-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-108937.
NSC15520
NSC15520 is a small molecular inhibitor of Replication Protein A (RPA). NSC15520 specifically recognizes the RPA N-terminal DNA binding domain (DBD), and blocks the interaction of RPA with p53 or RAD9. NSC15520 also inhibtis helix destabilization of a duplex DNA (dsDNA) oligonucleotide, involves in DNA replication, DNA repair, DNA recombination, and DNA damage response signaling[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 730960-98-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-138155.
NSC 185058
NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. Inhibition of ATG4B using NSC 185058 markedly attenuates autophagic activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 39122-38-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125169.
NSC 194308
NSC 194308, a U2AF2-RNA complexes enhancer, increases association of the U2AF1-U2AF2-SF1-splice site RNA complex by binding a site between the U2AF2 RNA recognition motifs (RRM1 and RRM2). NSC 194308 inhibits pre-mRNA splicing by stalling spliceosome assembly at the point where U2AF helps recruit U2 snRNP to the branchpoint. NSC 194308 enhances the binding of pre-mRNA to U2AF2, selectively triggering cell death in leukemia cell lines containing spliceosome mutations[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 90379-42-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153736.
NSC194598
NSC194598 is a p53 DNA-binding inhibitor with an IC50 value of 180 nM. NSC194598 inhibits p53 DNA binding and induction of target genesn when p53 is stabilized and activated by irradiation or chemotherapy. NSC194598 can interfere with transcriptional activation of mutated rearranged during transfection (RET) gene, induce apoptosis and G0/G1 phase arrest. NSC194598 can be used for the researches of acute radiation toxicity and medullary thyroid carcinoma[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5358-76-9. Pack Sizes: 1 mg. Product ID: HY-156135.
NSC 23005 Sodium Salt
NSC 23005 Sodium Salt is used to perpare sodium sodium cyclohexyl aminosulfonyl benzoate as p18 micromolecule inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1796596-46-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C13H16NNaO4S, Molecular Weight: 305.33. US Biological Life Sciences.
Worldwide
NSC232003
NSC232003 is a highly potent and cell-permeable UHRF1 inhibitor, which inhibits DNA methylation in vitro and disrupts DNMT1/UHRF1 interactions at a cellular level. Uses: Scientific research. Category: Signaling pathways. CAS No. 1905453-18-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-103236.
NSC 23766
NSC 23766 is a cell-permeable, reversible and specific inhibitor of Rac GTPase, used for cancer treatment. Uses: Scientific research. Category: Signaling pathways. CAS No. 733767-34-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15723.
NSC 23766 trihydrochloride
NSC 23766 trihydrochloride is an inhibitor of Rac1 activation. Uses: Scientific research. Category: Signaling pathways. CAS No. 1177865-17-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15723A.
NSC 23766 Trihydrochloride
NSC 23766 trihydrochloride is an inhibitor of Rac GTPase targeting Rac activation by guanine nucleotide exchange factors (GEFs) with IC50 of ~50 μM in a cell-free assay; does not inhibit the closely related targets, Cdc42 or RhoA. Group: Inhibitors. CAS No. 1177865-17-6. Pack Sizes: 10mg. Product ID: S8031. Formula: C24H35N7.3ClH. Smiles: CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C(N=C3C=C2)C)N)C.Cl.Cl.Cl. Storage Conditions: 2 years -80 in solvent.
United States; Europe
NSC243928 mesylate
NSC243928 mesylate is a human lymphocyte antigen 6 (LY6) binder, which also acts as an inhibitor of cell growth and has anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 59988-01-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-123885.
NSC 245214
NSC 245214 is a thienyl cycloalkanone that is part of the US National Cancer Institute small molecule repository. The biological activity of this compound has not been reported. Group: Biochemicals. Alternative Names: 2-(3,5-dinitro-2-thienyl)-cyclohexanone. Grades: Highly Purified. CAS No. 31554-45-7. Pack Sizes: 1mg, 5mg, 10mg, 25mg. Molecular Formula: C10H10N2O5S, Form: Supplied as a crystalline. US Biological Life Sciences.
Worldwide
NSC260594
NSC260594 induces Apoptosis. NSC260594 binds the shallow groove of the Mcl-1 protein, and inhibits Mcl-1 expression through down-regulation of Wnt signaling proteins. NSC260594 can also recognize G9-G10-A11-G12 RNA tetraloop of HIV and prevent the binding of the Gag protein within the 5-UTR. NSC260594 inhibits tumor growth, and can be used for research of Triple-negative breast cancers (TNBCs)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XMH95. CAS No. 906718-66-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-112591.
NSC 280449 is a derivative of Tromethamine (T892600); a compound that is widely used in biochemistry and molecular biology. In medicine, Tromethamine is used as an alternative to sodium bicarbonate in the treatment of metabolic acidosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 60204-53-7. Pack Sizes: 100mg, 500mg. Molecular Formula: C10H17NO3, Molecular Weight: 199.25. US Biological Life Sciences.
Worldwide
NSC2805
NSC2805 is a WWP2 ubiquitin ligase inhibitor that can significant inhibit WWP2 activity with an IC50 of 0.38 μM. NSC2805 can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4371-34-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134417.
NSC319726
NSC319726 (ZMC1) is a mutant p53R175 reactivator; inhibits growth of fibroblasts expressing the p53R175 mutation (IC50 = 8 nM); shows no inhibition for p53 wild-type cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZMC1. CAS No. 71555-25-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18634.
NSC 319726
NSC 319726. Group: Biochemicals. Grades: Purified. CAS No. 71555-25-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NSC 33994
NSC 33994. Group: Biochemicals. Grades: Purified. CAS No. 82058-16-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NSC348884
NSC348884 is a nucleophosmin (NPM) inhibitor, it disrupts oligomer formation and induces apoptosis, inhibits cell proliferation with IC50s of 1.7-4.0 μM in distinct cancer cell lines. NSC348884 can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 81624-55-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13915.
NSC 3852
NSC 3852. Group: Biochemicals. Grades: Purified. CAS No. 3565-26-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NSC 405020
NSC 405020. Group: Biochemicals. Grades: Purified. CAS No. 7497-7-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NSC 405020
NSC 405020 is a specific MMP14 inhibitor. NSC 405020 can directly interact with the hemopexin domain of MMP14. NSC 405020 reduces the expression of full length and active cleaved Notch3 (NICD3). NSC 405020 can be used to research vestibular schwannoma, hemostasis and thrombosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7497-7-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-15827.
NSC45586 sodium
NSC45586 sodium is an inhibitor of PHLPP. NSC45586 sodium targets the PP2C phosphatase domains of PHLPP1 and PHLPP2, blocks the phosphatase activity of PHLPP, increases the expression level of FOXO1 in the nucleus, and reduces the protein expression of PHLPP1. NSC45586 sodium activates the AKT survival signaling pathway, enhances IGF-1-induced AKT activation, and inhibits the phosphorylation of AKT/ERK under basal conditions. NSC45586 sodium reduces staurosporine-induced neuronal death, preserves notochord cell morphology and KRT19 expression, inhibits cell apoptosis (apoptosis), improves the viability and proliferation of nucleus pulposus cells, upregulates the expression of ACAN/SOX9, and downregulates the expression of MMP13. NSC45586 sodium binds tightly to bovine serum albumin (bovine serum albumin), and exerts a more significant effect on nucleus pulposus in male individuals. NSC45586 sodium can be used in studies related to global cerebral ischemia and intervertebral disc degeneration[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6300-44-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19820A.
NSC47924
NSC47924 is a laminin receptor (LR) inhibitor. NSC47924 affects 37/67 kDa LR cell surface localization and interaction with the cellular prion protein. NSC47924 can be used for testing prion diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6638-24-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122066.
NSC61610
NSC61610 disrupts hIL-18 binding to the ectromelia virus IL-18BP. NSC61610 inhibits hIL-18:ectvIL-18BP complex formation with an IC50 about 6?uM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 500538-94-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-102019.
NSC 617145
NSC 617145 is a selective werner syndrome helicase (WRN) helicase inhibitor with an IC50 value of 230 nM. NSC 617145 inhibits WRN ATPase, and induces double-strand breaks (DSB) and chromosomal abnormalities. NSC 617145 shows selective for WRN over BLM, FANCJ, ChlR1, RecQ, and UvrD helicases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 203115-63-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110185.
NSC 617145
NSC 617145. Group: Biochemicals. Grades: Purified. CAS No. 203115-63-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NSC622608
NSC622608 is a V-domain Ig suppressor of T-cell activation (VISTA) ligand with an IC50 value of 4.8 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2593254-90-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147311.
NSC624206
NSC624206 is an inhibitor of ubiquitin E1 (UBA1), with an IC50 of ~9 μM. NSC624206 specifically blocks ubiquitin-thioester formation (IC50=13 μM) but has no effect on ubiquitin adenylation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 13116-77-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-103436.
NSC 624206
NSC 624206. Group: Biochemicals. Grades: Purified. CAS No. 13116-77-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NSC 625987
NSC 625987. Group: Biochemicals. Grades: Purified. CAS No. 141992-47-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NSC 625987
NSC 625987 is a specific and high-affinity CDK4 inhibitor with an IC50 of 0.2 μM for CDK4:cyclin D1. NSC 625987 shows >500-fold selectivity for CDK4 over CDK2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 141992-47-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103380.
NSC 632839 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 157654-67-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NSC636819
NSC636819 is a competitive and selective inhibitor of KDM4A/KDM4B. KDM4A/KDM4B are potential progression factors for prostate cancer. NSC636819 has the potential for the research of cancer diseases, especially prostate cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1618672-71-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-110154.
NSC647889
NSC647889 is an apoptosis and autophagy inducer. NSC647889 induces apoptosis, inhibits mTOR pathway and abrogates DNA synthesis. NSC647889 triggers LC3-positive vesicle formation, modulates AKT and 4EBP1 phosphorylation and shows heightened caspase-3 activation in multicellular spheroids. NSC647889 can be used for the research of solid cancer tumour, head-neck carcinoma, and colorectal cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1033931-92-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176761.
NSC 663284
NSC 663284 (DA-3003-1) is a potent, cell-permeable, and irreversible Cdc25 dual specificity phosphatase inhibitor, has an IC50 for Cdc25B2 of 0.21 μM. NSC 663284 exhibits mixed competitive kinetics against Cdc25A, Cdc25B(2), and Cdc25C with Ki values of 29, 95, and 89 nM, respectively[1]. NSC 663284 inhibits NSD2 (IC50 of 170 nM) through a direct interaction with the catalytic SET domain (Kd of 370 nM)[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DA-3003-1. CAS No. 383907-43-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-100034.
NSC 663284
NSC 663284. Group: Biochemicals. Grades: Purified. CAS No. 383907-43-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
NSC668036
NSC668036 is a Dishevelled (Dvl) PDZ domain inhibitor with a Kd of 237 μM. NSC668036 blocks Wnt signaling by interrupting the Frizzled-Dvl interaction[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 144678-63-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-117666.