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| Product | Description | |
|---|---|---|
| NK 1001 | NK 1001 is produced by the strain of Streptomyces kanamyceticus var. NK 1001 has weak activity against gram-positive, gram-negative and mycobacterium bacteria. Synonyms: Antibiotic NK 1001; 4,6-Diamino-3-(hexopyranosyloxy)-2-hydroxycyclohexyl 6-amino-6-deoxyhexopyranoside. CAS No. 53025-93-7. Molecular formula: C18H35N3O12. Mole weight: 485.48. |  |
| NK-1013-1 | NK-1013-1 is an aminoglycoside antibiotic isolated from Streptomyces kanamyceticus var.21-16. It is active against gram-positive bacteria. Synonyms: Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-4)-O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-N(sup 3)-acetyl-, D-. CAS No. 102612-61-3. Molecular formula: C20H38N4O13. Mole weight: 542.5. | |
| NK-1013-2 | NK-1013-2 is an aminoglycoside antibiotic isolated from Streptomyces kanamyceticus var.21-16. It is active against gram-positive and gram-negative bacteria. Molecular formula: C22H40N4O14. Mole weight: 584.6. | |
| NK10958P | NK10958P is a plant growth regulator produced by Streptomyces sp. NK10958. Synonyms: NK-10958P. Molecular formula: C18H30O4. Mole weight: 310.4. | |
| NK-1145 Hydrochloride | The hydrochloride salt form of NK-1145, an azabicyclo derivative, has been found to be a parasympatholytic drug that could induce stimulation and excitement. Synonyms: NK-1145 hydrocholdoride; NK1145; NK 1145; NK-1145; Phenyl tropan-3alpha-yl ester; NK 1145; Tropine-3-beta-phenyl ether hydrochloride; 8-methyl-3-phenoxy-8-azabicyclo[3.2.1]octane hydrochloride(1:1). Grades: 98%. CAS No. 16487-37-9. Molecular formula: C14H20ClNO. Mole weight: 253.77. | |
| NK-122 | NK-122 is a potential bioactive agent. Uses: A potential bioactive agent. Synonyms: NK122; NK 122; NK-122; 1-(1H-indol-2-yl)-2-methylpropan-2-amine hydrochloride. Grades: ≥98%. CAS No. 3417-71-8. Molecular formula: C12H17ClN2. Mole weight: 224.73. | |
| NK 154183A | NK 154183A is a 24-membered macrolide antibiotic isolated from the fermentation broth of Streptomyces sp. NK154183. It exhibits antifungal and antitumor activity against the human colon adenocarcinoma. Synonyms: NK154183A; (4E, 18E)-11, 12, 13, 14, 16, 17, 27a-Heptahydroxy-6'-(2-hydroxybutyl)-2, 2, 11, 15, 17, 28-hexamethyl-2, 3, 3', 3a, 4', 5', 6, 6', 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 22, 23, 26, 27, 27a-tetracosahydro-20H-spiro[22, 26-methanofuro[2, 3-h][1, 5]dioxacyclohexacosine-24, 2'-pyran]-20-one. CAS No. 152986-47-5. Molecular formula: C41H70O13. Mole weight: 771. | |
| NK 154183B | NK 154183B is a 24-membered macrolide antibiotic isolated from the fermentation broth of Streptomyces sp. NK154183. It exhibits antifungal and antitumor activity against the human colon adenocarcinoma. Synonyms: NK154183B; (4E, 18E)-13-{[5-(Dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl]oxy}-11, 12, 14, 16, 17, 27a-hexahydroxy-6'-(2-hydroxybutyl)-2, 2, 11, 15, 17, 28-hexamethyl-2, 3, 3', 3a, 4', 5', 6, 6', 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 22, 23, 26, 27, 27a-tetracosahydro-20H-spiro[22, 26-methanofuro[2, 3-h][1, 5]dioxacyclohexacosine-24, 2'-pyran]-20-one. CAS No. 152986-49-7. Molecular formula: C49H85NO14. Mole weight: 912.2. | |
| NK1 receptor antagonist 2 | NK1 receptor antagonist 2 is a NK1 receptor antagonist. NK1 receptor antagonist 2 can be used for the research of tinnitus and hearing loss [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 579475-17-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145250. |  |
| NK 252 | NK 252 is a Nrf2 activator. It can induce expression of an antioxidant response element promoter driven reporter gene. Synonyms: NK-252; NK 252; NK252; N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)urea. Grades: ≥98% by HPLC. CAS No. 1414963-82-8. Molecular formula: C13H11N5O3. Mole weight: 285.26. | |
| NK 252 | NK 252. Group: Biochemicals. Grades: Purified. CAS No. 1414963-82-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| NK-252 | NK-252 is a potential Nrf2 activator, which exhibits a great Nrf2 -activating potential. Uses: Scientific research. Group: Signaling pathways. CAS No. 1414963-82-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19734. | |
| NK30424A | NK30424A is an inhibitor of lipopolysaccharide-induced tumour necrosis factor alpha production with IC50 value of 1 μmol/L. It is produced by Streptomyces sp. NA30424. Molecular formula: C30H46N2O10S. Mole weight: 626.8. | |
| NK30424B | NK30424B is an inhibitor of lipopolysaccharide-induced tumour necrosis factor alpha production with IC50 value of 0.9 μmol/L. It is produced by Streptomyces sp. NA30424. Molecular formula: C30H46N2O10S. Mole weight: 626.8. | |
| NK314 | NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that shows strong antitumor activity. It inhibited topoisomerase II activity and stabilized topoisomerase II-DNA cleavable complexes. The DNA breaks occurred within 1h after treatment with NK314 even without digestion of topoisomerase II by proteinase K, whereas etoposide required digestion of the enzyme protein in cleavable complex to detect DNA breaks. Pretreatment with topoisomerase II catalytic inhibitors, ICRF-193 and suramin, reduced both cleavable complex-mediated DNA breaks and proteinase K-independent DNA breaks, but protease inhibitors and nuclease inhibitors only decreased the latter. These results indicate that NK314 might affect topoisomerase II in the different manner from cleavable complex formation and activate intracellular proteinase and nuclease to produce DNA fragmentation. As a result of this unique mechanism of DNA breakage, NK314 showed substantial growth inhibition of topoisomerase II inhibitor-resistant tumors. Synonyms: NK-314; NK 314. Grades: 98%. CAS No. 208237-49-4. Molecular formula: C22H18ClNO4. Mole weight: 395.84. | |
| NK374200 | NK374200 is an insecticidal agent produced by Taralomyces. Molecular formula: C12H17N7O3. Mole weight: 307.31. | |
| N-(Ketocaproyl)-D,L-homoserine lactone | N-(Ketocaproyl)-D,L-homoserine lactone. Group: Biochemicals. Grades: Highly Purified. CAS No. 76924-95-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C10H15NO4. US Biological Life Sciences. | Worldwide |
| N-(Ketocaproyl)-L-homoserine lactone | N-(Ketocaproyl)-L-homoserine lactone. Group: Biochemicals. Alternative Names: N-(3-Oxohexanoyl)-homoserine lactone; (S)-3-Oxo-N-(tetrahydro-2-oxo-3-furanyl)hexanamide. Grades: Highly Purified. CAS No. 143537-62-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C10H15NO4. US Biological Life Sciences. | Worldwide |
| N-(Ketocaproyl)-L-homoserine Lactone (N-(3-Oxohexanoyl)-homoserine Lactone) | An autoinducer of P. fischeri luciferase. A specfic genetic regulator that is unrelated to at least one of the enzyme systems that it induces, and it acts after excretion and accumulation in the extracellular medium. Group: Biochemicals. Alternative Names: N-(3-Oxohexanoyl)-homoserine Lactone. Grades: Highly Purified. CAS No. 143537-62-6. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| NKH 477 | NKH477 is a water-soluble analog of forskolin, which is an adenylyl cyclase activator, but it is sparingly soluble in aqueous solutions. It has both inotropic and vasodilator effects. Uses: Vasodilator agents. Synonyms: NKH 477; NKH477; NKH-477; N,N-Dimethyl-(3R,4aR,5S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester β-alanine hydrochloride. Grades: ≥98% by HPLC. CAS No. 138605-00-2. Molecular formula: C27H43NO8.HCl. Mole weight: 546.1. | |
| NKH 477 | NKH 477 is a water-soluble analog of Forskolin, that is a potent activator of adenylyl cyclase, which shows some selectivity for cardiac (type V) adenylyl cyclase). Group: Biochemicals. Alternative Names: N,N-Dimethyl- β-alanine (3R, 4aR, 5S, 6S, 6aS, 10S, 10aR, 10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-10, 10b-dihydroxy-3, 4a, 7, 7, 10a-pentamethyl-1-oxo-1H-naphtho[2, 1-b]pyran-6-yl Ester HCl; N,N-Dimethyl- β-alanine [3R-(3α,4a β,5 β,6 β, 6aα, 10α, 10a β,10bα)]-5-(Acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl Ester HCl; 1H-Naphtho[2,1-b]pyran, β-alanine deriv.; 6- (3-Di methyl aminopropionyl) forskolin HCl; Adehl; Colforsin Dapropate HCl. Grades: Highly Purified. CAS No. 138605-00-2. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C??H??ClNO?, Molecular Weight: 546.09. US Biological Life Sciences. | Worldwide |
| NKL-22 | NKL-22 is a HDAC inhibitor with IC 50 value of 78 uM. It is a cell-permeable pimeloylanilide compound which acts as a FXN-(frataxin gene) specific HDAC inhibitor. It increase frataxin protein concentrations. It increase FXN mRNA in FRDA lymphocytes. Uses: Nkl-22 it increase fxn mrna in frda lymphocytes. Synonyms: HDAC inhibitor IV; NKL 22; NKL-22; NKL22; MDK-4154; MDK4154; MDK4154; N-(2-Aminophenyl)-N'-phenylheptanediamide;HDAC inhibitor IV;N1-(2-Aminophenyl)-N7-phenylheptanediamide;Histone Deacetylase Inhibitor IV. Grades: 98%. CAS No. 537034-15-4. Molecular formula: C19H23N3O2. Mole weight: 325.40. | |
| NKY80 | NKY80 is a inhibitor of adenylyl cyclase (AC). NKY80 exhibits greater affinity for AC5 over AC3 and AC2 (IC50 values are 8.3 μM, 132 μM and 1.7 mM respectively). Uses: Designed for use in research and industrial production. Additional or Alternative Names: NKY80; NKY 80; NKY-80. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 299442-43-6. Molecular formula: C12H11N3O2. Mole weight: 229.24. Purity: >98%. IUPACName: 2-amino-7-(furan-2-yl)-5,6,7,8-tetrahydroquinazolin-5-one. Canonical SMILES: O=C1C2=CN=C(N)N=C2CC(C3=CC=CO3)C1. Product ID: ACM299442436-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: NY-80. |  |
| NKY 80 | NKY80 is a selective inhibitor of adenylyl cyclase 5 with IC50 value of 8.3 μM. Synonyms: NKY80; NKY 80; NKY-80. 2-Amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quinazolinone. Grades: ≥98% by HPLC. CAS No. 299442-43-6. Molecular formula: C12H11N3O2. Mole weight: 229.23. | |
| NKY 80 | NKY 80. Group: Biochemicals. Grades: Purified. CAS No. 299442-43-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NL-103 | NL-103, a nicotinamide derivative, has been found to be an inhibitor of both histone deacetylases and hedgehog pathway. It was found to exhibit activity in decreasing the expression of Gli2 so that could probably be significant in the biological studies of Hh pathway. Synonyms: NL-103; NL 103; NL103; N-(4-chloro-3-(3-chlorobenzamido)phenyl)-6-((7-(hydroxyamino)-7-oxoheptyl)amino)nicotinamide. Grades: 98%. CAS No. 1788896-33-2. Molecular formula: C71H108N18O14. Mole weight: 1437.76. | |
| N-Lactoyl-Phenylalanine | N-Lactoyl-Phenylalanine is a blood-derived signaling metabolite that can be induced by exercise. N-Lactoyl-Phenylalanine can reduce obesity and improve glucose tolerance [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Lac-Phe. CAS No. 183241-73-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-150012. | |
| N-Lactylleucine | N-Lactylleucine is an endogenous metabolite that can be identified in patients with the intermediate type of maple syrup urine disease [1]. Uses: Scientific research. Group: Peptides. CAS No. 112757-17-2. Pack Sizes: 5 mg. Product ID: HY-164805. | |
| N-Lactylvaline | N-Lactylvaline is an endogenous metabolite that can be identified in patients with the intermediate type of maple syrup urine disease [1]. Uses: Scientific research. Group: Peptides. CAS No. 70190-98-6. Pack Sizes: 5 mg. Product ID: HY-164804. | |
| N-Lauroyl-L-alanine | N-Lauroyl-L-alanine is an alanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 52558-74-4. Pack Sizes: 10 g; 25 g; 100 g. Product ID: HY-W009379. | |
| N-Lauroylsarcosine | N-lauroylsarcosine is an anionic surfactant, and can be used as a permeation enhancer. The mixture of N-lauroylsarcosine in 25-50% ethanol acts synergistically to increase skin permeability, which may be useful for transdermal drug delivery research [1]. Uses: Scientific research. Group: Peptides. CAS No. 97-78-9. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-W141881. | |
| N-LAUROYLSARCOSINE | N-LAUROYLSARCOSINE. Synonyms: n-methyl-n-(1-oxododecyl)-glycin;N-methyl-N-(1-oxododecyl)-Glycine;N-LAUROYLSARCOSINE FREE ACID;N-acyl sarcosinate;Glycine, N-methyl-N-(1-oxododecyl)-;n-lauroylsarcosine,neat;N-Lauroylsarkosin;N-Dodecanoyl-N-methylglycine, Sarkosyl L. CAS No. 97-78-9. Pack Sizes: 1 kg. Product ID: CDF4-0094. Molecular formula: C15H29NO3. Category: Food Emulsifiers. Product Keywords: Food Ingredients; Food Emulsifiers; N-LAUROYLSARCOSINE; CDF4-0094; 97-78-9; C15H29NO3; 202-608-3; 97-78-9. Purity: 0.99. Color: White or Colorless to Almost White or Almost colorless. EC Number: 202-608-3. Physical State: Powder to lump to Clear Liquid. Solubility: almost transparency in Methanol. Application: N-Lauroylsarcosine may be used as a permeation enhancer in the transdermal drug delivery formulations since it increases the fluidity of stratum corneum lipid structure of the skin. Boiling Point: 413.2±28.0 °C(Predicted). Melting Point: 45-49 °C. Product Description: N-Lauroylsarcosine is an anionic surfactant with an ability to denature proteins. Due to its microbicidal property, N-lauroylsarcosine is being considered as a potent anti-microbicide in topical formulations,?especially against sexually transmitted diseases (STDs). |  |
| N-Lauroylsarcosine sodium salt | 500g Pack Size. Group: Amino Acids, Biochemicals. Formula: C15H28NNaO3. CAS No. 137-16-6. Prepack ID 12615111-500g. Molecular Weight 293.38. See USA prepack pricing. |  |
| NLCQ-1 | NLCQ-1 is a novel weakly DNA-intercalative bioreductive compound. NLCQ-1 exhibited a C50 of 44 microM. NLCQ-1 demonstrated significant hypoxic selectivity in several rodent (V79, EMT6, SCCVII) or human (A549, OVCAR-3) tumor cell lines. Its potency as a hypoxic cytotoxin ranged between 10 and 136 microM x h, for the cell lines tested, at 30 microM input concentration. NLCQ-1 was a very potent and efficient radiosensitizer of hypoxic V79 cells, providing SER values of 2.27-2.56 at 20-80 microM concentration (measured at 10% survival level). Preclinical results suggest a possible use of NLCQ-1 as adjuvants to radiotherapy. Synonyms: NLCQ 1; NLCQ1; NSC 709257; NSC-709257; NSC709257; 4-(3-(2-nitro-1-imidazolyl)-propylamino)-7-chloroquinoline hydrochloride. CAS No. 221292-08-6. Molecular formula: C15H15Cl2N5O2. Mole weight: 368.22. | |
| NLG-919 | NLG919 is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), a cytosolic enzyme responsible for the oxidation of the essential amino acid tryptophan into kynurenine. By inhibiting IDO1 and decreasing kynurenine in tumor cells, this agent increases tryptophan levels, restores the proliferation and activation of various immune cells, including dendritic cells (DCs), natural killer (NK) cells, T-lymphocytes, and causes a reduction in tumor-associated regulatory T-cells (Tregs). Synonyms: GDC0919; GDC-0919; GDC 0919; NLG919; NLG 919; NLG-919; RG6078; RG-6078; RG 6078. Grades: > 98%. CAS No. 1402836-58-1. Molecular formula: C18H22N2O. Mole weight: 282.38. | |
| N-L-γ-glutamyl-L-tyrosine | N-L-γ-glutamyl-L-tyrosine is a dipeptide produced by the catabolism of proteins. Synonyms: Gamma-Glutamyltyrosine; H-gamma-Glu-Tyr-OH; H-Glu(Tyr-OH)-OH. Grades: ≥95%. CAS No. 7432-23-7. Molecular formula: C14H18N2O6. Mole weight: 310.31. | |
| N-lignoceroyl-D-erythro-sphingosine | N-lignoceroyl-D-erythro-sphingosine. Group: Biochemicals. Grades: Highly Purified. CAS No. 102917-80-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C42H83NO3. US Biological Life Sciences. | Worldwide |
| N-Linked Timolol Impurity HCl | An impurity of Ticlopidine which is a non-cardioselective beta-blocker and it has no intrinsic sympathomimetic or membrane stabilizing effect. Grades: > 95%. Molecular formula: C13H24N4O3S.HCl. Mole weight: 352.89. | |
| N-L-Lysyl-L-glutamic acid | N-L-Lysyl-L-glutamic acid. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| N-L-Lysyl-L-glutamic acid | Synonyms: Lys-Glu-OH; Lys Glu OH. Grades: ≥ 99% (TLC). CAS No. 45234-02-4. Molecular formula: C11H21N3O5. Mole weight: 275.30. | |
| N-(long-chain-acyl)ethanolamine deacylase | Does not act on N-acylsphingosine or N,O-diacylethanolamine. Group: Enzymes. Synonyms: N-acylethanolamine amidohydrolase; acylethanolamine amidase. Enzyme Commission Number: EC 3.5.1.60. CAS No. 99283-61-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4450; N-(long-chain-acyl)ethanolamine deacylase; EC 3.5.1.60; 99283-61-1; N-acylethanolamine amidohydrolase; acylethanolamine amidase. Cat No: EXWM-4450. |  |
| N-Losartanyl-losartan | N-Losartanyl-losartan |  Sarchem Laboratories New Jersey NJ |
| NLP-28 | NLP-28 is an antimicrobial peptide found in Caenorhabditis elegans, and has antifungal activity. Synonyms: Neuropeptide-like protein 28. Grades: >85%. | |
| NLP-31 | NLP-31 is an antimicrobial peptide found in Caenorhabditis elegans, and has antifungal activity against D.coniospora. It has weak antibacterial activity against gram-positive bacteria M.luteus and gram-negative E.coli. Synonyms: Neuropeptide-like protein 31. Grades: >85%. | |
| N-(L-Prolyl)- β-alanine | N-(L-Prolyl)- β-alanine is a derivative of β-Alanine (A637320); a naturally occurring beta amino acid that is formed in vivo by the degradation of Dihydro Uracil (D449990) and Carnosine (C184190). β-Alanine is also the rate-limiting precursor of Carnosine, as a result supplementation with β-alanine increases the concentration of Carnosine in muscles. Group: Biochemicals. Grades: Highly Purified. CAS No. 112558-45-9. Pack Sizes: 100mg, 1g. Molecular Formula: C8H14N2O3, Molecular Weight: 186.21. US Biological Life Sciences. | Worldwide |
| N-L-Prolyl-L-histidine | Prolyl-histidine is a dipeptide composed of proline and histidine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: H-Pro-His-OH; H-PH-OH; L-prolyl-L-histidine; Prolyl-Histidine; L-Histidine, L-prolyl-; (S)-3-(1H-Imidazol-4-yl)-2-((S)-pyrrolidine-2-carboxamido)propanoic acid; N-prolyl histidine. Grades: ≥95%. CAS No. 92027-43-5. Molecular formula: C11H16N4O3. Mole weight: 252.27. | |
| NLRP3-IN-11 | NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC 50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2769040-91-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148187. | |
| NLRP3-IN-18 | NLRP3-IN-18 (compound 13) is a potent NLRP3 inhibitor with an IC 50 value of ≤1.0 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2769040-06-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153554. | |
| NLRP3-IN-2 | NLRP3-IN-2, an intermediate substrate in the synthesis of glyburide, inhibits the formation of the NLRP3 inflammasome in cardiomyocytes and limits the infarct size following myocardial ischemia/reperfusion in the mouse, without affecting glucose metabolism [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 16673-34-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W011082. | |
| NLRP3-IN-25 | NLRP3-IN-25 (compound 32) is an orally available NLRP3 inhibitor with anti-inflammatory activity. NLRP3-IN-25 attenuates renal injury in doxorubicin-induced glomerulonephritis in mice. NLRP3-IN-25 inhibits IL-1β secretion in THP-1 cells with an IC 50 of 21 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2660230-90-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155463. | |
| NLRP3-IN-9 | NLRP3-IN-9 is an inhibitor of caspase-1 and NLRP3 ATPase activities. It acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NLRP3-IN-9; NLRP3 IN 9; NLRP3IN9; INF-4E; INF 4E; INF4E. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 88039-46-7. Molecular formula: C12H13ClO3. Mole weight: 240.68. Purity: >98%. IUPACName: Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate. Canonical SMILES: C=C(C(C1=CC=CC=C1Cl)O)C(OCC)=O. Product ID: ACM88039467. Alfa Chemistry ISO 9001:2015 Certified. Categories: NLRP3 inflammasome. | |
| NLS-Cas9-D10A Nickase | NLS-Cas9-D10A Nickase. Nls-cas9-d10a nickase is a mutation form of cas9 nuclease which makes one active domain deactivated, thus it can only cut one single strand dna that is complementary to the guide-rna, producing one single strand cut. combined with two different grna, nls-cas9-d10a nickase produces two cut sites respectively and causes a double strand break. compared with the wild type cas9 nuclease, the two-grna guided cleavage can significantly reduce the off target effects. Group: Cloning Enzymes. Purity: 10μg; 50μg. Storage: Store at -20 ?. Source: E.coli. Pack: 10 mM Tris, 300 mM NaCl, 0.1 mM EDTA, 1 mM DTT, 50% Glycerol pH7.4 at 25 °C. Cat No: CE-3505. | |
| NLS-Cas9-EGFP Nuclease | NLS-Cas9-EGFP Nuclease. Nls-cas9-egfp is a fusion protein contains a nuclear localization sequence (nls) on its n terminal and egfp on the c terminal. the egfp can be used as a reporter for tracking or sorting transfected cells, which enables the possibility of enriching cell populations for desired genome edits via fluorescence activated cell sorting (facs). it significantly reduces the labor and cost associated with single cell cloning and genotyping in genome editing applications. Group: Cloning Enzymes. Purity: 100μg; 500μg. Storage: Store at -20 ?. Source: E.coli. Pack: 10 mM Tris, 300 mM NaCl, 0.1 mM EDTA,1 mM DTT, 50% Glycerol PH7.4, at 25°C. Cat No: CE-3506. | |
| NLS-Cas9-NLS Nuclease | NLS-Cas9-NLS Nuclease. Nls-cas9-nls is produced by expression in an e. coli strain carrying a plasmid encoding the cas9 gene from streptococcus pyogenes with a double-ends nuclear localization signal (nls). it can be used for genome editing by inducing site-specific dna double stranded breaks. cas9 protein forms a very stable ribonucleoprotein (rnp) complex with the guide rna (grna) component of the crispr/cas9 system, which can localize to the nucleus immediately once entering the cell with the guide of the nls. compared with the mrna or plasmid systems, transcription and translation processes are not required. this dna-free system avoids the risk of inserting foreign dna into the genome, which can be quite useful for gene editing-based disease therapy. our highly pure and active cas9 nuclease meets all of the researcher´s requirements (e.g. in vitro cleavage assay, rnp complex transfection, micro injection). Group: Cloning Enzymes. Purity: 50μg; 100μg. Storage: Store at -20 ?. Source: E.coli. Pack: 10 mM Tris, 300 mM NaCl, 0.1 mM EDTA, 1 mM DTT, 50% Glycerol pH7.4 at 25?. Cat No: CE-3504. | |
| NLS (PKKKRKV) acetate | NLS (PKKKKKV) is a peptide that enhances nuclear entry into the field of gene transfer research. It is derived from the simian virus 40 large tumor antigen (SV40 large T antigen). Synonyms: NLS PKKKRKV acetate. Molecular formula: C42H82N14O10. Mole weight: 943.21. | |
| NLS-StAx-h | NLS-StAx-h is a cell-permeable Wnt inhibitor that potently suppresses β-catenin-transcription factor interactions. CAS No. 2872559-21-0. Molecular formula: C161H275N55O29. Mole weight: 3445.26. | |
| N-(L-Valyl) Valganciclovir Hydrochloride | N-(L-Valyl) Valganciclovir Hydrochloride is a dipeptide monoester prodrugs of the antiviral drug Ganciclovir. Synonyms: L-Valyl-L-valine 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3- hydroxypropyl Ester Hydrochloride. Grades: > 95%. Molecular formula: C19H32N7O6Cl. Mole weight: 489.96. | |
| NLY01 | NLY01 is a long-acting, microglia-targeted GLP-1R agonist, which is undergoing clinical trials for the treatment of Parkinson's Disease and Alzheimer's Disease. Synonyms: NLY 01; NLY-01. | |
| NM-3 | NM-3 is an orally bioavailable antiangiogenic isocoumarin with potential antineoplastic activity. NM-3 inhibits vascular endothelial growth factor (VEGF), a pro-angiogenic growth factor, thereby inhibiting endothelial cell proliferation. This agent also induces apoptosis by a mechanism involving reactive oxygen species. Synonyms: NM 3; NM3; isocoumarin NM-3; 2-(8-hydroxy-6-methoxy-1-oxo-1H-isochromen-3-yl)propanoic acid. CAS No. 181427-78-1. Molecular formula: C13H12O6. Mole weight: 264.23. | |
| N-Maleimido Butyryl Oxy Succinimide ester | N-Maleimido Butyryl Oxy Succinimide ester. CAS No. 80307-12-6. Pack Sizes: Milligram Quantities: 100 mg. Order Number: CL226. |  www.prochemonline.com |
| N-Maleimidomethanol | N-Maleimidomethanol. Group: Biochemicals. Alternative Names: N-Methylolmaleimide; N- (Hydroxymethyl) maleimide; 1-(Hydroxymethyl)-1H-pyrrole-2,5-dione. Grades: Highly Purified. CAS No. 5063-96-7. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C5H5NO3. US Biological Life Sciences. | Worldwide |
| N-Maleimidomethanol (N-Methylolmaleimide) | A sulfhydryl reactive crosslinking reagent. Group: Biochemicals. Alternative Names: N-Methylolmaleimide. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| N-malonylurea hydrolase | Forms part of the oxidative pyrimidine-degrading pathway in some microorganisms, along with EC 1.17.99.4 (uracil/thymine dehydrogenase) and EC 3.5.2.1 (barbiturase). Group: Enzymes. Synonyms: ureidomalonase. Enzyme Commission Number: EC 3.5.1.95. CAS No. 368888-22-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4487; N-malonylurea hydrolase; EC 3.5.1.95; 368888-22-6; ureidomalonase. Cat No: EXWM-4487. | |
| NMD670 | NMD670 is an orally active inhibitor of skeletal muscle specific chloride channel ClC-1 with an EC 50 of 1.6 μM. NMD670 enhances neuromuscular transmission and improves muscle contraction and strength. NMD670 can be used in the study of muscle weakness and muscle fatigue [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2354321-33-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158183. | |
| NMDA | NMDA is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Uses: Scientific research. Group: Natural products. Alternative Names: N-Methyl-D-aspartic acid. CAS No. 6384-92-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-17551. | |
| NMDA | NMDA is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Unlike glutamate, NMDA only binds to and regulates the NMDA receptor and has no effect on other glutamate receptors. Uses: Excitatory amino acid agonists. Synonyms: LC488A; LC 488A; LC-488A. Grades: >98%. CAS No. 6384-92-5. Molecular formula: C5H9NO4. Mole weight: 147.13. | |
| NMDA Antagonist XI, N1-dansyl-spermine (NMDA Channel Blocker, N1-dansyl-spermine, N1-DnsSpm) | An N-sulfonyl-polyamine that acts as a potent and more specific antagonist ofnMDA receptors expressed in Xenopus oocytes (IC50 = 310, 340nM in NR1/NR2A and NR1/NR2B, respectively). The inhibition appears to be voltage-dependent and is non-competitive with respect to glutamate and glycine. Exhibits about 50-fold greater selectivity over NR1/NR2C and NR1/NR2D receptors (IC50 = 16 and 13uM, respectively). Also shown to block c-AMP-dependent, calmodulin-activated phosphodiesterase (IC50 = 58uM) and diminishes the induction of ornithine decarboxylase. At higher concentration (100uM) it is shown to reduce spontaneous epileptiform activity in mouse cortical slices. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NMDAR2C/2D Inhibitor, DQP-1105 (DQP-1105, NMDA Antagonist IV) | A dihydroquinilone-pyrazoline NMDA antagonist, which is selective for NMDA receptors that are comprised of recombinant subunits GluN1/GluN2C (IC50 = 5.4uM) and GluN1/GluN2D (2.2uM) over GluN1/GluN2B (206uM) and GluN1/ClucN2A (undetectable) in Xenopus oocytes. Similar selectivity is observed in whole-cell HEK patch-clamp assays with IC50 values for GluN2C and GluN2D that are at least 50-fold lower than those for recombinant GluN2A, GluN2B, GluA1, or GluK2-containing receptors. It inhibits NMDA by blocking a conformational change necessary for channel opening and is non-competitive with co-agonists, glutamate and glycine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NMDA Receptor NR2BCT(1292-1304)-TAT (Tat-NR2BCT, H-KKNRNKLRRQHSY-Ahx-YGRKKRRQRRR-NH2) | A 13-mer NMDA receptor 2B (NR2B) subunit carboxy terminal (1292-1304) derived peptide that specifically binds DAPK1 (death-associated protein kinase 1) in a reversible manner and antagonizes the activated DAPK1-NR2B interaction and the potentiation of nMDAR function with no effect on either the catalytic activity of DAPK1 or the nMDA receptor physiology. Blocks Ca2+ influx through extrasynaptic nMDA receptors (at 50uM) and the blood-brain-barrier permeable version, namely NR2BCT(1292-1304) attached to TAT(47-57) via a spacer (6-aminohexanoic acid) protects cortical neurons from nMDA receptor-mediated insults and reduces brain infarction and improve neurological functions in mice (10mg/kg, i.v.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C???H???N??O??, Molecular Weight: 3382. US Biological Life Sciences. | Worldwide |
| NmDef02 | NmDef02 is an antimicrobial peptide found in Nicotiana megalosiphon, and has antimicrobial activity. It belongs to the defensin family. Synonyms: Putative defensin. Grades: >98%. | |
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