A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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| Product | Description | |
|---|---|---|
| Nurr1 agonist 7 | Nurr1 agonist 7 (compound 110) is a Nurr1 agonist with an EC50 value of 0.12 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 228707-95-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-157026. |  |
| Nurr1 inverse agonist-1 | Nurr1 inverse agonist-1 is an inverse agonist tool for the neuroprotective transcription factor Nurr1. Uses: Scientific research. Category: Signaling pathways. CAS No. 2758673-07-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132909. | |
| Nusinersen | Nusinersen is an antisense oligonucleotide active molecule. Nusinersen modifies the pre-messenger RNA splicing of the SMN2 gene, thereby promoting the production of full-length SMN protein. Nusinersen improves spinal muscular atrophy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1258984-36-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112980. | |
| Nusinersen(ASO, Oligonucleotides) | Nusinersen(ASO, Oligonucleotides). Category: Anti-muscular dystrophy apis. Synonyms: Nusinersen. Spinraza. CAS No. 1258984-36-9. Product ID: API1258984369. Molecular formula: C234H340N61O128P17S17. Mole weight: 7127. |  |
| Nutlin-3 | Nutlin-3 is a commercial available p53-MDM2 inhibitor, with Ki of 90 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 548472-68-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-50696. | |
| Nutlin-3 | Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM in a cell-free assay; stabilizes p73 in p53-deficient cells. Group: Inhibitors. CAS No. 890090-75-2. Pack Sizes: 5mg. Product ID: S1061. Formula: C30H30Cl2N4O4. Smiles: CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Nutlin-3 ((±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one) | Cell-permeable. Nutlin-3 is a Mdm2 (mouse double minute 2) antagonist (IC50=90nM for Nutlin-3a and 13.6uM for Nutlin-3b), p53 pathway activator, and apoptosis inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 548472-68-0. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. |  Worldwide |
| Nutlin-3a | Nutlin-3a (Rebemadlin), an active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). Nutlin-3a inhibits MDM2-p53 interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. Nutlin-3a has the potential for the study of TP53 wild-type ovarian carcinomas[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Rebemadlin. CAS No. 675576-98-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10029. | |
| Nutlin-3a | Nutlin-3a ((-)-Nutlin-3), the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM in a cell-free assay. Nutlin-3a induces autophagy and apoptosis in a p53-dependent manner. Group: Inhibitors. Alternative Names: (-)-Nutlin-3. CAS No. 675576-98-4. Pack Sizes: 5mg. Product ID: S8059. Formula: C30H30Cl2N4O4. Smiles: CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Nutlin-3b | Nutlin-3b, the inactive form of Nutlin-3 (HY-50696), is a p53/MDM2 inhibitor with an IC50 of 13.6 μM. Nutlin-3b is 150 times less potent in binding to MDM2 than Nutlin-3a (HY-10029). Nutlin-3b is promising for research of cancers[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 675576-97-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15335. | |
| Nutmeg Neolignan | Nutmeg Neolignan is a stereomixture of erythro-Δ8'-7-Ethoxy-4-hydroxy-3,3',5'-trimethoxy-8-O-4'-neolignan and threo-Δ8'-7-Ethoxy-4-hydroxy-3,3',5'-trimethoxy-8-O-4'-neolignan. The mixture is novel TRPM8 agonist from nutmeg as promising cooling compound. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C46H60O12, Molecular Weight: 804.96. US Biological Life Sciences. | Worldwide |
| Nutmeg oil | Nutmeg oil. Alternative Names: Nutmegoil,terpeneless. CAS No. 8008-45-5. Purity: 0.98. Product ID: CI-EO-0054. Molecular formula: C32H56. Mole weight: 440.8 g/mol. IUPAC Name: 2,2-dimethyl-3-methylidenebicyclo[2.2.1]heptane;(4R,6R)-1,6-dimethyl-4-propan-2-ylcyclohexene;(2R,4R)-2-methyl-1-methylidene-4-propan-2-ylcyclohexane. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Nutmeg Oil | Nutmeg Oil. CAS No. 8008-45-5. FEMA No. 2793. Kosher: Y. VIGON Item # 504819. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils. |  America & Internationally |
| Nutmeg Oil EI | """Indonesia is currently the largest producer of Nutmeg Oil in the world, providing 75% to 80% of the global supply. It is also one the top three largest producers of Mace Oil. The three areas where Nutmeg is mainly grown in Indonesia are Java, Aceh in North Sumatra and the spice island in around Sulawesi. 80 - 90% of the Nutmeg Oil processed is used for flavouring in beverages""". Uses: Oral care and pharmaceutical, Aromatherapy, Personal Care, Perfumery. Group: Plant Extracts. INCI Names: Myristica Fragrans (Nutmeg) Kernel Oil. Grades: FOOD GRADE. CAS No. 84082-68-8 ; 8008-45-5. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: NM-005. Olfactive Profile: Spicy, terpenic, sweet, warm, woody. EC No: 282-013-3. FEMA No: 2793. Origin: Indonesia. |  New Jersey |
| Nutmeg Oil (Java | Bogor 9% Myristicin) | Indonesia is currently the largest producer of Nutmeg Oil in the world, providing 75% to 80% of the global supply. It is also one the top three largest producers of Mace Oil. The three areas where Nutmeg is mainly grown in Indonesia are Java, Aceh in North Sumatra and the spice island in around Sulawesi. 80 - 90% of the Nutmeg Oil processed is used for flavouring in beverages. Uses: Flavor, Oral Care, Fragrance Products, Personal Care. Group: Plant Extracts. INCI Names: Myristica Fragrans (Nutmeg) Kernel Oil. Grades: FOOD GRADE. CAS No. 84082-68-8 ; 8008-45-5. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: NM-001. Olfactive Profile: Spicy, terpenic, sweet, warm, woody. EC No: 282-013-3. FEMA No: 2793. Origin: Indonesia. | New Jersey |
| Nutmeg Oil Safrole Free | "Indonesia is currently the largest producer of Nutmeg Oil in the world, providing 75% to 80% of the global supply. It is also one the top three largest producers of Mace Oil. The three areas where Nutmeg is mainly grown in Indonesia are Java, Aceh in North Sumatra and the spice island in around Sulawesi. 80 - 90% of the Nutmeg Oil processed is used for flavouring in beverages". Uses: Fragrance, Personal Care. Group: Plant Extracts. INCI Names: Myristica Fragrans (Nutmeg) Kernel Oil. Grades: FOOD GRADE. CAS No. 84082-68-8 ; 8008-45-5. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: NM-004. Olfactive Profile: Spicy, terpenic, sweet, warm, woody. EC No: 282-013-3. FEMA No: 2793. Origin: Indonesia. | New Jersey |
| Nutmeg Oil Terpeneless | Nutmeg Oil Terpeneless. CAS No. 8008-45-5. FEMA No. 2793. Kosher: Y. VIGON Item # 504917. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils. | America & Internationally |
| Nutmeg Powder | Nutmeg Powder. |  CA, FL & NJ |
| Nutriacholic Acid | Nutriacholic Acid. Group: Biochemicals. Alternative Names: 3α-Hydroxy-7-oxo-5 β-cholan-24-oic Acid; 3α-Hydroxy-7-oxo-5 β-cholanic Acid; 3α-Hydroxy-7-oxo-5 β-cholanoic Acid; 3α-Hydroxy-7-oxo-5 β-cholic Acid; 5 β-Cholanic Acid-3α-ol-7-one; 7-Ketochenodeoxycholic Acid; 7-Ketolithocholic Acid; 7-Oxo-3α-hydroxycholan-24-oic Acid; 7-Oxolithocholic Acid; 7-Keto-Lithocholic Acid; NSC 226118; 3α-Hydroxy-7-oxo-5 β-cholanic Acid; 3α-Hydroxy-7-oxo-5 β-cholan-24-oic Acid; (3α,5 β)-3-Hydroxy-7-oxo-cholan-24-oic Acid. Grades: Highly Purified. CAS No. 4651-67-6. Pack Sizes: 1g. Molecular Formula: C24H38O4, Molecular Weight: 390.56. US Biological Life Sciences. | Worldwide |
| Nutritional Coatings | Nutritional Coatings. Product ID: PE-0192. Category: Coating Systems Excipients. Product Keywords: Pharmaceutical Excipients; Coating Systems Excipients; Nutritional Coatings; PE-0192. Standard: ChP, USP, BP, EP, JP. Grade: Food grade, Pharmaceutical grade. |  |
| Nuzhenide - Suppliers needed. | NuzhenideCategoryiridoid glycoside, plant compound, antioxidant | Suppliers Needed |
| NV03 | NV03 is a potent and selective antagonist of Ubiquitin-like with PHD and RING finger domains 1 (UHRF1)-H3K9me3 interaction by binding to UHRF1 tandem tudor domain, with a Kd of 2.4 μM. NV03 is also a ligand for E3 ligase. NV03 can be studied in anticancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2448341-58-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125292. | |
| NV-354 | NV-354 (Mitochondria modulator-1) (compound 1) is a mitochondrial regulator that stimulates mitochondrial ATP production. NV-354 has good oral bioavailability, blood-brain barrier permeability, and good plasma stability. NV-354 has the potential to study mitochondrial diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mitochondria modulator-1. CAS No. 866465-21-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-153715. | |
| NV-5138 | NV-5138, a leucine analog, is the first selective and orally active brain mTORC1 activator, binding to Sestrin2. NV-5138 possesses rapid antidepressant effects. Synonyms: 4-(difluoromethyl)-L-leucine; ((S)-2-Amino-5,5-difluoro-4,4-dimethylpentanoic acid. Grade: ≥98%. CAS No. 2095886-80-7. Molecular formula: C7H13F2NO2. Mole weight: 181.18. |  |
| NV914 | NV914 is an inhibitor of FTSJ1 (tryptophan tRNA-specific 2'-O-methyltransferase) that inhibits the methyltransferase activity of FTSJ1, induces translational readthrough of premature termination codons, and enables genes carrying nonsense mutations to synthesize full-length proteins. NV914 belongs to translational readthrough-inducing compounds (TRIDs). NV914 exhibits translational readthrough activity against nonsense mutations in in vitro systems, does not induce readthrough of natural termination codons, and restores CFTR protein expression. NV914 shows favorable acute oral tolerance in mice, with low health risks and good safety profiles. NV914 is applicable to research related to cystic fibrosis and Shwachman-Diamond syndrome[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2341941-41-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-177963. | |
| N-valeryl-D,L-penicillamine | N-valeryl-D,L-penicillamine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| N-Vanillylnonanamide | 1g Pack Size. Group: Biochemicals, Organics, Research Organics & Inorganics. Formula: C17H27NO3. CAS No. 2444-46-4. Prepack ID 28253688-1g. Molecular Weight 293.4. See USA prepack pricing. |  |
| N-vinyl-2-pyrrolidinone copolymer | N-vinyl-2-pyrrolidinone copolymer. CAS No. 25086-89-9. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  |
| N-Vinyl-2-pyrrolidone | N-Vinyl-2-pyrrolidone. Group: Biochemicals. Alternative Names: 1-Vinyl-2-pyrrolidinone; 1-Vinylpyrrolidin-2-one. Grades: Highly Purified. CAS No. 88-12-0. Pack Sizes: 1kg, 2kg, 5kg. US Biological Life Sciences. | Worldwide |
| N-Vinyl-2-pyrrolidone 99+% (GC) | N-Vinyl-2-pyrrolidone 99+% (GC). Group: Biochemicals. Grades: GC. CAS No. 88-12-0. Pack Sizes: 100g, 250g, 1Kg, 4Kg, 5Kg. US Biological Life Sciences. | Worldwide |
| N-Vinyl-2-pyrrolidone, NVP | N-Vinyl-2-pyrrolidone, NVP. Applications: N-vinyl-2-pyrrolidone (nvp) is commonly used as a reactive diluent for radiation curing in uv-coating, uv-inks, and uv adhesives. it is used as a monomer to produce water soluble polyvinylpyrrolidone (pvp) with uses in pharmaceuticals, oil field, cosmetics, food additives & adhesives. it is used in the manufacture of copolymers with, for example, acrylic acid, acrylates, vinyl acetate and acrylonitrile and in the synthesis of phenolic resins. Category: Pharmaceutical excipients. Synonyms: 1-VINYL-2-PYRROLIDINONE, 99+%;N-Vinyl-2-pyrrolidone, stabilized with Kerobit;N-Vinyl-2-pyrrolidone, stabilized, 98%;N-VINYL-2-PYRROLIDINONE;N-VINYL-2-PYRROLIDONE;N-VINYLPYRROLIDONE;N-VINYLBUTYROLACTAM;1-ethenyl-2-pyrrolidinon. Grades: DMF. CAS No. 88-12-0. Product ID: PIE-0030. Molecular formula: C6H9NO. Mole weight: 111.14. Appearance: Colorless to yellow liquid. | |
| N-Vinyl-2-pyrrolidone (stabilized with N,N'-Di-sec-butyl-p-phenylenediamine) | N-Vinyl-2-pyrrolidone (stabilized with N,N'-Di-sec-butyl-p-phenylenediamine). Alternative Names: 1-Ethenyl-2-pyrrolidinone. CAS No. 88-12-0. Purity: >99.0%. Product ID: FFC-AR-88120. Molecular formula: C6H9NO. Mole weight: 111.14. IUPAC Name: 1-ethenylpyrrolidin-2-one. Alfa Chemistry - ISO 9001:32057 Certified. | |
| N-Vinylacetamide | N-Vinylacetamide. CAS No. 5202-78-8. Molecular formula: C4H7NO. Mole weight: 85.1g/mol. IUPAC Name: N-ethenylacetamide. SMILES: CC(=O)NC=C. InChI: InChI=1S/C4H7NO/c1-3-5-4(2)6/h3H,1H2,2H3,(H,5,6). |  |
| N-Vinyl acetamide(nva) | N-Vinyl acetamide(nva). CAS No. 5202-78-8. Molecular formula: C4H7NO. Mole weight: 85.1g/mol. IUPAC Name: N-ethenylacetamide. SMILES: CC(=O)NC=C. InChI: InChI=1S/C4H7NO/c1-3-5-4(2)6/h3H,1H2,2H3,(H,5,6). | |
| N-Vinyl-ε-caprolactam | Liquid; OtherSolid. CAS No. 2235-00-9. Molecular formula: C8H13NO. Mole weight: 139.19g/mol. IUPAC Name: 1-ethenylazepan-2-one. SMILES: C=CN1CCCCCC1=O. InChI: InChI=1S/C8H13NO/c1-2-9-7-5-3-4-6-8(9)10/h2H,1,3-7H2. | |
| N-Vinyl-epsilon-caprolactam | 100g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C8H13NO. CAS No. 2235-00-9. Prepack ID 90026843-100g. Molecular Weight 139.19. See USA prepack pricing. | |
| N-Vinyl-ε-caprolactam (stabilized with HO-TEMPO) | Liquid; OtherSolid. CAS No. 2235-00-9. Molecular formula: C8H13NO. Mole weight: 139.19g/mol. IUPAC Name: 1-ethenylazepan-2-one. SMILES: C=CN1CCCCCC1=O. InChI: InChI=1S/C8H13NO/c1-2-9-7-5-3-4-6-8(9)10/h2H,1,3-7H2. | |
| N-Vinylphthalimide | N-Vinylphthalimide. Alternative Names: 2-Vinylisoindoline-1,3-dione. CAS No. 3485-84-5. Molecular formula: C10H7NO2. Mole weight: 173.17. Purity: >98.0%(GC)(N). IUPAC Name: 2-ethenylisoindole-1,3-dione. SMILES: C=CN1C(=O)c2ccccc2C1=O. InChI: 1S/C10H7NO2/c1-2-11-9(12)7-5-3-4-6-8(7)10(11)13/h2-6H,1H2. | |
| N-Vinylphthalimide | 1g Pack Size. Group: Building Blocks, Organics. Formula: C10H7NO2. CAS No. 3485-84-5. Prepack ID 89997051-1g. Molecular Weight 173.17. See USA prepack pricing. | |
| N-Vinylphthalimide | Off-white powder, 97%. Synonym: 2-Ethenylisoindoile-1,3-dione. CAS No. 3485-84-5. Pack Sizes: Typically in stock: 25g, 100g. Mole weight: 173.17. MP/BP: M.P. 85-87. Order No: FR-2735. |  Frinton Laboratories |
| N-Vinylpyrrolidone | Polyvinylpyrrolidone is a white powder. Compatible with a wide range of hydrophilic and hydrophobic resins. (NTP, 1992);Liquid;White or nearly white powder;YELLOW-TO-BROWN HYGROSCOPIC POWDER.;COLOURLESS-TO-YELLOW LIQUID.;White powder. Molecular formula: (C6H9NO)n;C6H9NO;C6H9NO. Mole weight: 111.14g/mol. IUPAC Name: 1-ethenylpyrrolidin-2-one. SMILES: C=CN1CCCC1=O. InChI: InChI=1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2. | |
| n-vinylpyrrolidone/styrene copolymer | n-vinylpyrrolidone/styrene copolymer. CAS No. 25086-29-7. Molecular formula: C14H17NO. | |
| N-Vinylpyrrolidone Technical 95%min | N-Vinylpyrrolidone Technical 95%min. | |
| NVP-2 | NVP-2 is a potent and selective ATP-competitive cyclin dependent kinase 9 (CDK9) probe, inhibits CDK9/CycT activity with an IC50 of 0.514 nM. NVP-2 displays inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases with IC50 values of 0.584 μM, 0.706 μM, and 0.605 μM, respectively. NVP-2 induces cell apoptosis.[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1263373-43-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12214A. | |
| NVP 231 | NVP 231 is a potent, specific, and reversible ceramide kinase (CerK) inhibitor(IC50=12 nM) that competitively inhibits binding of ceramide to CerK[1]. NVP 231 induces cell apoptosis by increasing DNA fragmentation and caspase-3 and caspase-9 cleavage[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 362003-83-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13945. | |
| NVP 231 | NVP 231. Group: Biochemicals. Grades: Purified. CAS No. 362003-83-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NVP-231 | NVP-231. Group: Biochemicals. Alternative Names: N-[2-(Benzoylamino)-6-benzothiazolyl]-tricyclo[3.3.1.13, 7]decane-1-carboxamide; NVP 231. Grades: Highly Purified. CAS No. 362003-83-6. Pack Sizes: 10mg. Molecular Formula: C25H25N3O2S, Molecular Weight: 431.55. US Biological Life Sciences. | Worldwide |
| NVP-AAM077 Tetrasodium Hydrate (NVP-AAM077, [[[ (1S) -1- (4-Bromophenyl) ethyl]amino] (1, 2, 3, 4-tetrahydro-2, 3-dioxo-5-quinoxalinyl) methyl] Phosphonic Acid Tetrasodium Hydrate, PEAQX Tetrasodium Hydrate, NMDA Antagonist VII) | A potent antagonist for NMDA receptors. Modestly higher selectivity for the NR2A than for the NR2B containing NMDA receptors (IC50 = 0.015 and 0.078uM) but insufficient to discriminate between NR2A and NR2B-containing NMDA receptors. Widely used for researches in synaptic plastic, learning and memory, and epilepsy. Group: Biochemicals. Grades: Highly Purified. CAS No. 459836-30-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| NVP ADW 742 | NVP ADW 742. Group: Biochemicals. Grades: Purified. CAS No. 475488-23-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NVP-ADW742 | NVP-ADW742 (ADW742) is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 μM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADW742; GSK 552602A; ADW. CAS No. 475488-23-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10252. | |
| NVP-AEW541 | NVP-AEW541 (AEW541 ) is an orally active inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with an IC50 value of 0.15 μM. NVP-AEW541 also inhibits InsR, IC50 with a value of 0.14 μM. NVP-AEW541 has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AEW541. CAS No. 475489-16-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50866. | |
| NVP-AUY 922 | NVP-AUY 922 is a potent inhibitor of heat shock protein 90 (Hsp90) that prevents the proliferation of a range of human cancer cell lines. NVP-AUY 922 has been shown to enhance the radiation sensitivity of tumor cell lines under hypoxia. Group: Biochemicals. Alternative Names: 5-[2, 4-Dihydroxy-5- (1-methylethyl) phenyl]-N-ethyl-4-[4- (4-morpholinylmethyl) phenyl]-3-isoxazolecarboxamide; VER 52296; NVP-AUY922. Grades: Highly Purified. CAS No. 747412-49-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NVP-BAG956 | NVP-BAG956 is an ATP-competitive PI3K inhibitor with IC50s of 34, 56, 112 and 444 nM for PI3Kδ, PI3Kα, PI3Kγ and PI3Kβ, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAG 956. CAS No. 853910-02-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13333. | |
| NVP-BAG956 | NVP-BAG956. Group: Biochemicals. Alternative Names: 2-Methyl-2- [4- [2-methyl-8- [ (pyridin-3-yl) ethynyl] imidazo [4, 5-c] quinolin-1-yl] phenyl] propionitrile; BAG 956; NVP-BAG 956; α , α -Dimethyl-4- [2-methyl-8- (3-pyridinylethynyl) -1H-imidazo [4, 5-c] quinolin-1-yl] benzeneacetonitrile. Grades: Highly Purified. CAS No. 853910-02-8. Pack Sizes: 10mg. Molecular Formula: C28H21N5, Molecular Weight: 427.5. US Biological Life Sciences. | Worldwide |
| NVP-BEZ 235 | Inhibitor of phosphatidylinositol 3-kinases, P13K and mTOR. Group: Biochemicals. Alternative Names: 4-[2,3-Dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4,5-c]quinolin-1-yl]-α,α-dimethyl-benzeneacetonitrile; 2-Methyl-2- [4- [3-methyl-2-oxo-8- (quinolin-3-yl) -2, 3-dihydroimidazo [4, 5-c] quinolin-1-yl] phenyl] propionitrile; BEZ 235. Grades: Highly Purified. CAS No. 915019-65-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NVP BHG 712 | NVP BHG 712. Group: Biochemicals. Grades: Purified. CAS No. 940310-85-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| NVP-BHG712 | NVP-BHG712 is an oral active EphB4 kinase autophosphorylation inhibitor, with IC50 values of 3.3 nM and 3.0 nM for EphA2 and EphB4, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BHG712. CAS No. 940310-85-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13258A. | |
| NVP-BKM 120 | NVP-BKM 120. Group: Biochemicals. Alternative Names: BKM 120; Buparlisib; 5-(2,6-di-4-Morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine. Grades: Highly Purified. CAS No. 944396-07-0. Pack Sizes: 5mg. Molecular Formula: C18H21F3N6O2, Molecular Weight: 410.39. US Biological Life Sciences. | Worldwide |
| NVP-BSK805 | NVP-BSK805 is an ATP-competitive JAK2 inhibitor, with IC50s of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM for JAK2 JH1 (JAK homology 1), JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1092499-93-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14722. | |
| NVP-CGM097 | NVP-CGM097 is a potent and selective MDM2 inhibitor with IC50 of 1.7±0.1 nM for hMDM2. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CGM097. CAS No. 1313363-54-0. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15954. | |
| NVP-DFF332 | HIF-2α-IN-8 is a potent and orally active HIF2α inhibitor with IC50 values of 9, 37, 246 nM for HIF2α SPA, HIF2α iScript, HIF2α HRE RGA, respectively. HIF-2α-IN-8 shows antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HIF-2α-IN-8. CAS No. 2734922-78-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148860. | |
| NVP-DFV890 | NVP-DFV890 is an orally administered, selective NLRP3 inhibitor. NVP-DFV890 directly binds to NLRP3, blocks maturation of pro-inflammatory cytokines IL-1β and IL-18, and inhibits pyroptotic cell death. NVP-DFV890 acts as an inducer of viral clearance, promoting earlier clearance of SARS-CoV-2. NVP-DFV890 can be used for the research of COVID-19 pneumonia and coronavirus-associated acute respiratory distress syndrome (CARDS)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NLRP3 antagonist 2. CAS No. 2271394-34-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155876. | |
| NVP-DKY709 | NVP-DKY709 is an orally active and selective IKZF2 molecular glue degrader with the Dmax and DC50 of 53% and 4 nM, respectively. In addition, NVP-DKY709 can degrade IKZF4 (DC50: 13 nM) and SALL4 (DC50: 2 nM). NVP-DKY709 exerts anti-tumor activity by binding with CRBN to change conformation and recruit and degrade IKZF2[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2291360-73-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-144998. | |
| NVP DPP 728 dihydrochloride | NVP DPP 728 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 207556-62-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NVP-HSP990 | NVP-HSP990 is a potent, selective and orally active Hsp90 inhibitor, with IC50 values of 0.6, 0.8, and 8.5 nM for Hsp90α, Hsp90β, and Grp94, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HSP-990. CAS No. 934343-74-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15190. | |
| NVP-TAE 226 | NVP-TAE 226 (TAE226) is a potent and ATP-competitive dual FAK and IGF-1R inhibitor with IC50s of 5.5 nM and 140 nM, respectively. NVP-TAE 226 (TAE226) also effectively inhibits Pyk2 and insulin receptor (InsR) with IC50s of 3.5 nM and 44 nM, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAE226. CAS No. 761437-28-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13203. | |
| NVP-TAE 684 | NVP-TAE 684 (TAE 684) is a highly potent and selective ALK inhibitor, which blocks the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAE 684. CAS No. 761439-42-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10192. | |
| NVP-TNKS656 | NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM, and is > 300 fold selectivity against PARP1 and PARP2. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TNKS656. CAS No. 1419949-20-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13990. | |
| NVR 3-778 | NVR 3-778 is a first-in-Class and oral bioavailable HBV CAM (capsid assembly modulator) belonging to the SBA (sulfamoylbenzamide) class, with anti-HBV activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1445790-55-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124600. | |
| NVS-CECR2-1 | NVS-CECR2-1, a non-BET family Bromodomain (BRD) inhibitor, is a potent and selective cat eye syndrome chromosome region, candidate 2 (CECR2) inhibitor. NVS-CECR2-1 binds to CECR2 BRD with high affinity (IC50=47 nM; KD=80 nM). NVS-CECR2-1 exhibits cytotoxic activity and induces apoptosis against various cancer cells by targeting CECR2 as well as via CECR2-independent mechanism[1]. NVS-CECR2-1 is a chemical probe. Uses: Scientific research. Category: Signaling pathways. CAS No. 1992047-61-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110374. | |
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