A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
In enzymology, an aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) is an enzyme that catalyzes the chemical reaction: an aldehyde + NAD(P)+ + H2O <-> an acid + NAD(P)H + H+. The 4 substrates of this enzyme are aldehyde, NAD+, NADP+, and H2O, whereas its 4 products are acid, NADH, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. This enzyme participates in 5 metabolic pathways: glycolysis / gluconeogenesis, histidine metabolism, tyrosine metabolism, phenylalanine metabolism, and metabolism of xenobiotics by cytochrome p450. Applications: Component of nadh and nadph recycling systems. Group: Enzymes. Synonyms: aldehyde:NAD(P)+ oxidoreductase; aldehyde dehydrogenase [NAD(P)+]; ALDH; Aldehyde Dehydrogenase; EC 1.2.1.5. Enzyme Commission Number: EC 1.2.1.5. CAS No. 9028-88-0. ALDH. Activity: ~20 units/mg protein (At 25 °C with acetaldehyde as the substrate.). Form: Lyophilized. Source: Yeast. aldehyde:NAD(P)+ oxidoreductase; aldehyde dehydrogenase [NAD(P)+]; ALDH; Aldehyde Dehydrogenase; EC 1.2.1.5. Cat No: NATE-0902.
Native Yeast Coenzyme A, Trilithium Salt
Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle. All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of cellular enzymes use it (or a thioester, such as acetyl-CoA) as a substrate. In humans, CoA biosynthesis requires cysteine, pantothenate, and adenosine triphosphate (ATP). Group: Coenzymes. Synonyms: Coenzyme A, Trilithium Salt; CoA-Li; 18439-24-2. CAS No. 18439-24-2. Purity: Determined by enzyme analysis with PTA* (> 75%) *PTA = Phosphotrasacetylase (LM) (EC 2.3.1.8.). CoA. Mole weight: 685.41. Storage: Keep tightly stoppered in the dark below 5°C. For Prolonged storage, keep below-20°C. Source: Yeast. Coenzyme A, Trilithium Salt; CoA-Li; 18439-24-2. Cat No: NATE-0146.
Native Yeast Formate Dehydrogenase
Formate dehydrogenase is involved in the stress response of plants and catalyzes the reduction of NAD+ to NADH. Dehydrogenase that catalyzes the interconversion of formate to carbon dioxide. rely on the proven diagnostic quality of this product. Applications: Use formate dehydrogenase in diagnostic tests for the determination of oxalate in combination with oxalate decarboxylase or for the determination of formic acid. also used in cofactor recycling systems for nadh. Group: Enzymes. Synonyms: formate-NAD oxidoreductase; FDH; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formate benzyl-viologen oxidoreductase; formic acid dehydrogenase. FDH. Activity: >0.4 U/mg. Stability: At +2 to +8°C within specification range for 12 months. Store dry. Appearance: White lyophilizate. Source: Yeast. EC 1.2.1.2; 9028-85-7; formate-NAD oxidoreductase; FDH; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formate benzyl-viologen oxidoreductase; formic acid dehydrogenase. Cat No: NATE-0978.
Native Yeast Malate Dehydrogenase
Malate dehydrogenase is an enzyme in the citric acid cycle that catalyzes the conversion of malate into oxaloacetate (using NAD+) and vice versa (this is a reversible reaction). Malate dehydrogenase is not to be confused with malic enzyme, which catalyzes the conversion of malate to pyruvate producing NADPH. Malate dehydrogenase is also involved in gluconeogenesis, the synthesis of glucose from smaller molecules. Pyruvate in the mitochondria is acted upon by pyruvate carboxylase to form oxaloacetate, a citric acid cycle intermediate. In order to get the oxaloacetate out of the mitochondria, malate dehydrogenase reduces it to malate, and it then traverses the inner mitochondr.te: NAD+ oxidoreductase; EC 1.1.1.37; Malate Dehydrogenase. Enzyme Commission Number: EC 1.1.1.37. CAS No. 9001-64-3. MDH. Activity: > 1,000 units/mg protein (at 25°C and pH 7.5). Storage: 1 -10°C. Form: Ammonium sulfate suspension. Source: Yeast. malic dehydrogenase; L-malate dehydrogenase; NAD-L-malate dehydrogenase; malic acid dehydrogenase; NAD-dependent malic dehydrogenase; NAD-malate dehydrogenase; NAD-malic dehydrogenase; malate NAD dehydrogenase; NAD-dependent malate dehydrogenase; NAD-sp; ECific malate dehydrogenase; NAD-linked malate dehydrogenase; MDH; L-malate-NAD+ oxidoreductase; S-malate: NAD+ oxidoreductase; EC 1.1.1.37; Malate Dehydrogenase. Cat No: NATE-1030.
Native Yeast Phytase
Phytase catalyzes the hydrolysis of phytic acid to inositol and free orthophosphate. Wheat phytase can degrade inositol phosphate-6 and 5 at a pH of 4 and 5. Group: Enzymes. Synonyms: myo-inositol-hexakisphosphate 4-phosphohydrolase; 9001-89-2; 6-phytase; phytase; phytate 6-phosphatase; myo-inositol-hexakisphosphate 6-phosphohydrolase; 4-phytase; EC 3.1.3.26. Enzyme Commission Number: EC 3.1.3.26. CAS No. 9001-89-2. Phytase. Activity: 5000 u/g. Storage: Store at -20°C. Form: Powder. Source: Yeast. myo-inositol-hexakisphosphate 4-phosphohydrolase; 9001-89-2; 6-phytase; phytase; phytate 6-phosphatase; myo-inositol-hexakisphosphate 6-phosphohydrolase; 4-phytase; EC 3.1.3.26. Cat No: NATE-0565.
Native Zucchini Ascorbate Oxidase
In enzymology, a L-ascorbate oxidase (EC 1.10.3.3) is an enzyme that catalyzes the chemical reaction:2 L-ascorbate + O2? 2 dehydroascorbate + 2 H2O. Thus, the two substRates of this enzyme are L-ascorbate and O2, whereas its two products are dehydroascorbate and H2O. This enzyme belongs to the family of oxidoreductases, specifically those acting on diphenols and related substances as donor with oxygen as acceptor. This enzyme participates in ascorbate metabolism. It employs one cofactor, copper. Applications: Aao can be used in clinical tests for determining levels of ascorbic acid in blood or for the removal of interference effects caused by ascorbic acid in clinical analysis. Group: Enzymes. Synonyms: ascorbase; ascorbic acid oxidase; ascorbate oxidase; ascorbic oxidase; ascorbate dehydrogenase; L-ascorbic acid oxidase; AAO; L-ascorbate:O2 oxidoreductase; AA oxidase; EC 1.10.3.3; L-ascorbate ox. Enzyme Commission Number: EC 1.10.3.3. CAS No. 9029-44-1. Mole weight: 70kD. Activity: > 100 units/mg protein. Appearance: Light tanish, brownish, greyish to blue green free flowing powder. Form: Freeze dried powder. Source: Zucchini. ascorbase; ascorbic acid oxidase; ascorbate oxidase; ascorbic oxidase; ascorbate dehydrogenase; L-ascorbic acid oxidase; AAO; L-ascorbate:O2 oxidoreductase; AA oxidase; EC 1.10.3.3; L-ascorbate oxidase. Cat No: NATE-1137.
Native Zymomonas mobilis Alcohol Dehydrogenase
Alcohol dehydrogenases (ADH) are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+ to NADH). In Humans and many other animals, they serve to break down alcohols that otherwise are toxic, and they also participate in geneRation of useful aldehyde, ketone, or alcohol groups during biosynthesis of various metabolites. In yeast, plants, and many bacteria, some alcohol dehydrogenases catalyze the opposite reaction as part of fermentation to ensure a constant supply of NAD+. Applications: The enzyme is useful for determination of alcohols or aldehydes. Group: Enzymes. Synonyms: aldehyde reductase; ADH. Enzyme Commission Number: EC 1.1.1.1. CAS No. 9031-72-5. Alcohol dehydrogenase. Mole weight: ca. 148,000; Subunit molecular weight : ca. 37,000. Appearance: Lyophilized. Storage: Stable at -20 °C for at least six months. Source: Zymomonas mobilis. aldehyde reductase; ADH; alcohol dehydrogenase (NAD); aliphatic alcohol dehydrogenase; ethanol dehydrogenase; NAD-dependent alcohol dehydrogenase; NAD-specific aromatic alcohol dehydrogenase; NADH-alcohol dehydrogenase; NADH-aldehyde dehydrogenase; primary alcohol dehydrogenase; yeast alcohol dehydrogenase; EC 1.1.1.1; 9031-72-5. Cat No: NATE-1900.
Native Zymomonas mobilis Glucokinase
Glucokinase (EC 2.7.1.2) is an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate. Glucokinase occurs in cells in the liver, pancreas, gut, and brain of humans and most other vertebrates. In each of these organs it plays an important role in the regulation of carbohydrate metabolism by acting as a glucose sensor, triggering shifts in metabolism or cell function in response to rising or falling levels of glucose, such as occur after a meal or when fasting. Mutations of the gene for this enzyme can cause unusual forms of diabetes or hypoglycemia. Applications: The enzyme is useful for diagnostic reagent, for example, glucose determination or ck determination, and for the specificdetermination of glucose. tris-hci buffer is not suitable for the practical use of zm-gck. Group: Enzymes. Synonyms: EC 2.7.1.2; glucokinase; glucokinase (phosphorylating); 9001-36-9; GCK; FGQTL3; GK; GLK; HHF3; HK4; HKIV; HXKP; LGLK; MODY2. Enzyme Commission Number: EC 2.7.1.2. CAS No. 9001-36-9. GCK. Mole weight: ca. 66,000; Subunit molecular weight : ca. 33,000. Appearance: Lyophilized. Storage: Stable at -20 °C for at least one year. Source: Zymomonas mobilis. EC 2.7.1.2; glucokinase; glucokinase (phosphorylating); 9001-36-9; GCK; FGQTL3; GK; GLK; HHF3; HK4; HKIV; HXKP; LGLK; MODY2. Cat No: NATE-1903.
Glucose-6-phosphate dehydrogenase (G6PD or G6PDH) (EC 1.1.1.49) is a cytosolic enzyme that catalyzes the chemical reaction:D-glucose 6-phosphate + NADP+ <-> 6-phospho-D-glucono-1,5-lactone + NADPH + H+. This enzyme is in the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells (such as erythrocytes) by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). Applications: The enzyme is useful for diagnostic reagent, for example, glucose determination or ck determination, and for the specificdetermination of glucose. Group: Enzymes. Synonyms: Glucose-6-phosphate dehydrogenase; G6PD; G6PDH; Glucose-6-phosphate dehydrogenase (NADP(+)); EC 1.1.1.49; Glucose-6-phosphate 1-dehydrogenase; Glucose-6-phosphate dehydrogenase; GPD. Enzyme Commission Number: EC 1.1.1.49. CAS No. 9001-40-5. Glucose-6-phosphate dehydrogenase. Mole weight: ca. 208000; Subunit molecular weight: ca. 52,000. Appearance: Lyophilized. Storage: Stable at -20 °C for at least one year. Source: Zymomonas mobilis. Glucose-6-phosphate dehydrogenase; G6PD; G6PDH; Glucose-6-phosphate dehydrogenase (NADP(+)); EC 1.1.1.49; Glucose-6-phosphate 1-dehydrogenase; Glucose-6-phosphate dehydrogenase; GPD. Cat No: NATE-1898.
Na-Tosyl-L-arginine 98+%
Na-Tosyl-L-arginine 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences.
Worldwide
Na-Tosyl-L-arginine amide hydrochloride 98+%
Na-Tosyl-L-arginine amide hydrochloride 98+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 14279-64-2. Pack Sizes: 5g, 25g. US Biological Life Sciences.
Na-Tosyl-L-lysine methyl ester hydrochloride 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 5266-48-8. Pack Sizes: 1g, 2.5g. US Biological Life Sciences.
Worldwide
Na-Tosyl-Ne-Boc-L-lysine
Na-Tosyl-Ne-Boc-L-lysine. Group: Biochemicals. Alternative Names: Tos-L-Lys(Boc)-OH. Grades: Highly Purified. CAS No. 16948-09-7. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences.
Worldwide
Na-Tosyl-Ne-Boc-L-lysine 98+% (HPLC)
Na-Tosyl-Ne-Boc-L-lysine 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Na+-transporting two-sector ATPase
A multisubunit non-phosphorylated ATPase that is involved in the transport of ions. An enzyme found in alkaliphilic bacteria that is similar to EC 3.6.3.14 (H+-transporting two-sector ATPase) where Na+ replaces H+. Group: Enzymes. Enzyme Commission Number: EC 7.2.2.1 (Formerly EC 3.6.3.15). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4651; Na+-transporting two-sector ATPase; EC 3.6.3.15. Cat No: EXWM-4651.
Na-Trityl-D-asparagine 99+% (HPLC)
Na-Trityl-D-asparagine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
Na-Trityl-L-asparagine
Na-Trityl-L-asparagine. Group: Biochemicals. Grades: Reagent Grade. CAS No. 132388-58-0. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
Na-Trityl-Ne-Fmoc-L-lysine 99+% (HPLC)
Na-Trityl-Ne-Fmoc-L-lysine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
Natriuretic Peptide, C-Type
Natriuretic Peptide, C-Type. Uses: For analytical and research use. CAS No. 127869-51-6. Mole weight: 2197.60. Catalog: AP127869516-A.
Natriuretic Peptide, C-Type, Human and Porcine - CAS 127869-51-6
Natriuretic Peptide, C-Type, Human and Porcine - CAS 127869-51-6. Uses: For analytical and research use. CAS No. 127869-51-6. Mole weight: 2197.60. Catalog: AP127869516-B.
Nattokinase
Nattokinase is an enzyme extracted and purified from a Japanese food called Natto. Natto is a food made from fermented soybeans that has been eaten in Japan for many years. Natto is produced by fermentation by adding the bacterium Bacillus natto, a beneficial bacteria, to boiled soybeans. The resulting nattokinase enzyme is produced when the bacterium acts on the soybeans. While other soy foods contain enzymes, it is only the natto preparation that contains the specific nattokinase enzyme. Applications: Functional health productspharmaceutical stufffood additive. Group: Others. Purity: 20000fu/g. Appearance: Light yellow to white powder. Nattokinase. Cat No: EXTC-134.
Nattokinase
Nattokinase is a fermentation product of Bacillus natto, a protease with special activity, and has broad development prospects in industries such as health care products and functional foods. Grades: 5000 U/g; 20000 U/g. CAS No. 133876-92-3. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.12.
Nattokinase 20,000 Fu/gm
Nattokinase 20,000 Fu/gm.
CA, FL & NJ
Natto powder
Natto powder. Applications: Natto powder can be used in functional food, drinks, health care products and pharmaceuticals. Group: Others. Appearance: Light yellow powder. Source: NATTO is a fermented food with probiotic properties made according to a traditional Japanese recipe. This Natto is produced through the fermentation of organic soy with Bacillus subtilis natto, a very special bacterium imported from Japan. Natto powder. Cat No: EXTC-208.
Caprylyl glycol is a humectant that can also boost or aid the preservation of cosmetic formulations. It can be used as an alternative to parabens or other preservatives that may be undesirable. It can be used alone or in combination with certain ingredients to achieve completely preservative-free claims. Uses: For analytical and research use. Alternative Names: 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol. CAS No. 1117-86-8. Molecular formula: C8H18O2. Mole weight: 146.13. IUPAC Name: octane-1,2-diol. Catalog: APB1117868.
Natural Compound Library in Chinese Pharmacopoeia
A unique collection of 2070 natural products included in Chinese Pharmacopoeia (CP), a powerful tool for drug development and pharmacological study; - Diversified structures: including flavonoids, polyphenols, Alkaloids, etc. ; - Detailed compound information with structure, solubility, targeted signal pathways, action sites, and biological activity description; - Clear source: known active natural products selected from animals, plants, or microorganisms with clear species information; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6800. Categories: Natural Compound Libraries in Chinese Pharmacopoeia.
Naturally occurring substances. Alternative Names: Naturally occurring substances; Einecs 310-127-6. CAS No. 999999-99-4.
Natural Methyl Cinnamate
Methyl cinnamate is the methyl ester of cinnamic acid and is a white or transparent solid with a strong, aromatic odor. It is found naturally in a variety of plants, including in fruits, like strawberry, and some culinary spices, such as Sichuan pepper and some varieties of basil. Uses: Flavour and Perfume. Group: Plant Extracts. INCI Names: Methyl Cinnamate. Grades: FOOD GRADE. CAS No. 103-26-4. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: AM-002. Olfactive Profile: Fruity, balsamic, similar to strawberry. EC No: 203-093-8. FEMA No: 2698. Origin: Indonesia.
New Jersey
Natural Phytol 95% GC
Natural Phytol 95% GC. CAS No. 150-86-7.
CA, FL & NJ
Natural Product Derivatives Library
The library consists of more than 4, 000 members belonging 22 scaffolds (average 180 compounds per scaffold). - The library includes the following sub-libraries:- Cytisine-based sub-library- Matrine-based sub-library- Podophyllotoxin-based sub-library- Sub-library based on naturally occurring privileged BBS such ashydroxy-prolines, triptamine, nor-tropolone etc. - TargetMol "Beyond RO5" filters have been applied for the library population (See Phys-chem parameters for the library members). - NO Med-Chem restrictions (widely accepted and proprietary TargetMol substructure filters on reactive functionalities, toxicophoric, instability suspicions etc. ). - More than 90% purity for each library member confirmed by LC-MS or NMR analysis. Uses: Scientific use. Product Category: NY1000. Categories: Natural Product Derivatives Libraries.
Natural Product Derivatives Library for CADD
Large quantity: contains 135, 000 natural product derivatives and the number is continuously updating. Uses: Scientific use. Product Category: L6030. Categories: Natural Product Derivatives Libraries for CADD.
Natural Product Library
A unique collection of 3720 natural products that can be used for high-throughput screening and high-content screening. - Provides biological information and pharmacological information of the products, which serve as theoretical references and research basis for screening. - Clear source: a selection of known active natural products from animals, plants and microorganisms; plant species are labeled with accurate English and Latin names to facilitate your later research corroboration. - Good structural diversity: a wide range of compound structures including flavonoids and alkaloids, with detailed classification information. - NMR, HPLC/LCMS and other detection techniques to ensure the correct structure and high purity of the product and reduce false positives. Uses: Scientific use. Product Category: L6010. Categories: Natural Product Libraries.
Natural Product Library for HTS
A unique collection of 4160 pure natural products and their derivatives with known biological activity for drug discovery, pharmacological study, stem cell differentiation, fingerprint study and quality research, and can be used for high throughput screening (HTS) and high content screening (HCS); - Documentation with clear source: isolated natural products from plant, animal, microorganism, etc. - Structurally diverse: 4160 natural products, including diverse types of structures, such as alkaloids, limonoids, sequiterpenes, diterpenes, pentacyclic triterpenes, sterols, and many other representatives which provide the structural diversity inherent in this group; - Detailed compound information with structure, solubility, target, activity, IC50 value, and biological activity description; - Cost-effective and competitive price to save your fundings. Uses: Scientific use. Product Category: L6000. Categories: Natural Product Libraries for HTS.
Natural protease-enzyme blend for hair care
An all-natural protease-enzyme blend that enhances natural hair color and restores shine by removing excess protein-build up. Applications: Hair conditioners. Group: Enzymes. Synonyms: Natural protease; Natural protease enzyme blend; hair care; hair conditioners; protease enzyme blend; enhances natural hair color; enzyme for hair; natural hair color; Natural protease-enzyme blend for hair care. Cosmetic enzymes. Appearance: powder or liquid. Lipase; Cosmetic; lipase-based enzyme blend; breaks down human sebum; breaks down residual oil; human sebum; breaks down human sebum and residual oil; residual oil; human sebum; Lipase-based enzyme blend for cosmetic. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: BODY-2816.
Natural high-quality rose oil. Phthalate-free. Product ID: CI-HC-0167. Alfa Chemistry - ISO 9001:32057 Certified.
Natural Sodium Carbonate (Non-Food-Grade)
Sodium carbonate is a additive used as an acidity regulator, anticaking agent, raising agent, and stabilizer. The natural version of sodium carbonate can be used in products in order to boast the fully natural status of the product as opposed to containing synthetic chemicals. Uses: For analytical and research use. Alternative Names: Soda ash; Washing soda; Calcined soda. CAS No. 497-19-8. Molecular formula: Na2CO3. Mole weight: 105.99. IUPAC Name: disodium;carbonate. Catalog: APB497198.
Natural Tiramisu Flavor Powder (Non GMO)
Natural Tiramisu Flavor Powder (Non GMO).
CA, FL & NJ
Natural Vanilla Fragrance Oil
Natural high-quality fragrance. Phthalate-free. May cause cloudiness at high levels. Product ID: CI-HC-0174. Alfa Chemistry - ISO 9001:32057 Certified.
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;Bl
Nauclefine
Nauclefine is an indole alkaloid isolated from Nauclea officinalis. Nauclefine acts as a PDE3A modulator to induce cancer cell apoptosis through a PDE3A-SLFN12-dependent death pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 57103-51-2. Pack Sizes: 1 mg. Product ID: HY-N10149.
Nav1.1 activator 1
Nav1.1 activator 1 (compound 4), a highly potent Nav1.1 activator with BBB penetration, increases decay time constant (tau) of Nav1.1 currents at 0.03 μM along with significant selectivity against Nav1.2, Nav1.5, and Nav1.6[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2332897-85-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126429.
Nav1.7 blocker 24
Nav1.7 blocker 24 is a sodium channel blocker with selectivity for the voltage-gated Nav1.7 (pIC50 = 6.75). Alternative Names: 2-[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]-N-[[6-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]acetamide. Grades: 99%. CAS No. 1315451-25-2. Molecular formula: C20H16Cl2F3N3O3. Mole weight: 474.26.
Nav1.7-IN-19
Nav1.7-IN-19 is a potent, selective and orally active Nav1.7 inhibitor with an IC50 of 0.49 μM. Nav1.7-IN-19 shows high selectivity for Nav1.7, with selectivities of 312-fold and 662-fold against Nav1.1 and Nav1.5 in the inactivated state. Nav1.7-IN-19 exhibits weak inhibition on hERG potassium channels. Nav1.7-IN-19 exhibits analgesic effect and can be used for the research of neurological disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3097995-73-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-178494.
Nav1.7-IN-3
Nav1.7-IN-3 is a selective, orally bioavailable voltage-gated sodium channel Nav1.7 inhibitor with an IC50 of 8 nM. Pain relief. Limited CNS penetration[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1788872-06-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101789.
Nav1.7 inhibitor
Nav1.7 inhibitor (compound II), a sulfonamide, is a potent Nav1.7 inhibitor. Nav1.7 inhibitor has the potential for a wide range of disorders, particularly pain, including acute pain, inflammatory pain and/or neuropathic pain[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1355631-24-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13985.
Nav1.7 inhibitor
Nav1.7 inhibitor is a Voltage-gated sodium channel inhibitor that have probable effect in pain therapy and local anaesthesia. Uses: Nav1.7 inhibitor is a voltage-gated sodium channel inhibitor that have probable effect in pain therapy and local anaesthesia. Alternative Names: Nav1.7 inhibitor; NAV1.7-INHIBITOR; 1355631-24-1; 5-Chloro-4-((3,4-dichlorophenoxy)methyl)-2-fluoro-N-(methylsulfonyl)benzamide; 5-Chloro-4-[(3,4-dichlorophenoxy)methyl]-2-fluoro-N-(methylsulfonyl)benzamide; C15H11Cl3FNO4S. Grades: 98%. CAS No. 1355631-24-1. Molecular formula: C15H11Cl3FNO4S. Mole weight: 426.67.
NaV1.7 inhibitor-1
NaV1.7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1.7 inhibitor with an IC50 of 0.6 nM for hNaV1.7, exhibits 80-fold selectivity versus hNaV1.5[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1494585-79-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119934.
NAV 26
NAV 26. Group: Biochemicals. Grades: Purified. CAS No. 1198160-14-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Navacaprant
Navacaprant (BTRX-335140) is a selective and orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively.Navacaprant endows with favorable in vitro ADMET and in vivo pharmacokinetic profiles and medication-like duration of action in rats. Navacaprant distributes well into the CNS and can be used for the research of neuropathy[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BTRX-335140; CYM-53093. CAS No. 2244614-14-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-124754.
Navarixin
Navarixin (SCH 527123) is a potent, allosteric and orally active antagonist of both CXCR1 and CXCR2, with Kd values of 41 nM for cynomolgus CXCR1 and 0.20 nM, 0.20 nM, 0.08 nM for mouse, rat and cynomolgus monkey CXCR2, respectivelly[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SCH 527123; MK-7123. CAS No. 473727-83-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10198.
Navepdekinra
Navepdekinra (DC-806) is an orally active, potent interleukin-17A (IL-17A) inhibitor (IC50 = 10.81 nM). Navepdekinra disrupts the IL-17A protein-receptor interaction, suppressing the downstream pro-inflammatory signaling pathway. Navepdekinra inhibits arthritis in a collage-induced arthritis (CIA) rat model. Navepdekinra can be used for psoriasis, psoriatic arthritis, and ankylosing spondylitis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DC-806; LY4100504; S-011806. CAS No. 2467732-66-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153780.
Navitoclax
Navitoclax is an orally active, synthetic small molecule and an antagonist of a subset of the B-cell leukemia 2 (Bcl-2) family of proteins with potential antineoplastic activity. Uses: Antineoplastic agents. Alternative Names: ABT-263; ABT 263; ABT263; 4-[4-[[2-(4-chlorophenyl)-5,5-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide. Grades: 98%. CAS No. 923564-51-6. Molecular formula: C47H55ClF3N5O6S3. Mole weight: 974.611.
Navitoclax (ABT-263) is a potent and orally active Bcl-2 family protein inhibitor that binds to multiple anti-apoptotic Bcl-2 family proteins, such as Bcl-xL, Bcl-2 and Bcl-w, with a Ki of less than 1 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABT-263. CAS No. 923564-51-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10087.
Navitoclax (ABT-263)
Navitoclax (ABT-263) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤1 nM in cell-free assays, but binds more weakly to Mcl-1 and A1. Phase 2. Group: Inhibitors. CAS No. 923564-51-6. Pack Sizes: 1g. Product ID: S1001. Formula: C47H55ClF3N5O6S3. Smiles: CC1(CCC(=C(C1)CN2CCN(CC2)C3=CC=C(C=C3)C(=O)NS(=O)(=O)C4=CC(=C(C=C4)NC(CCN5CCOCC5)CSC6=CC=CC=C6)S(=O)(=O)C(F)(F)F)C7=CC=C(C=C7)Cl)C. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Navitoclax-piperazine
Navitoclax-piperazine is a B-cell lymphoma extra large (BCL-XL) inhibitor. Alternative Names: ABT-263-piperazine; (R)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((1-(phenylthio)-4-(piperazin-1-yl)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide; 4-(4-{[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl}-1-piperazinyl)-N-[(4-{[(2R)-1-(phenylsulfanyl)-4-(1-piperazinyl)-2-butanyl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamide. Grades: ≥98%. CAS No. 2143096-93-7. Molecular formula: C47H56ClF3N6O5S3. Mole weight: 973.63.
Navitoclax-piperazine
Navitoclax-piperazine (ABT-263-piperazine) is a Navitoclax (HY-10087) analog and BCL-XL inhibitor. Navitoclax-piperazine is the ligand for target protein of PROTAC DT2216 (HY-130604). Navitodax-pperaie and E3 ubiquitin ligase VHL ligand can be used to synthesize PROTAC DT2216 (HY-130604)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABT-263-piperazine. CAS No. 2143096-93-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-44432.