A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Na-Z-Ng-trityl-D-asparagine 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
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Na-Z-Ng-trityl-L-asparagine 99+% (HPLC)
Na-Z-Ng-trityl-L-asparagine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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Na-Z-Nim-benzyl-L-histidine 99+% (TLC)
Na-Z-Nim-benzyl-L-histidine 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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Na-Z-Nin-Boc-L-tryptophan dicylohexylammonium salt 99+% (HPLC)
Na-Z-Nin-Boc-L-tryptophan dicylohexylammonium salt 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Na-Z-Nw-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-D-arginine cyclohexylammonium salt 99+%
Na-Z-Nw-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-D-arginine cyclohexylammonium salt 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 200191-08-8. Pack Sizes: 250mg, 1g. US Biological Life Sciences.
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Na-Z-Nw- (4-methoxy-2, 3, 6-trimethyl Benzene sulfonyl) -D-arginine cyclohexylammonium salt 99+%
Na-Z-Nw- (4-methoxy-2, 3, 6-trimethyl Benzene sulfonyl) -D-arginine cyclohexylammonium salt 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 10g. US Biological Life Sciences.
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Na-Z-Nw- (4-methoxy-2, 3, 6-trimethyl Benzene sulfonyl) -L-arginine cyclohexylammonium salt 99+%
Na-Z-Nw- (4-methoxy-2, 3, 6-trimethyl Benzene sulfonyl) -L-arginine cyclohexylammonium salt 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences.
Worldwide
Na-Z-Nw- (4-methoxy Benzene sulfonyl) -L-arginine dicyclohexylammonium salt 99+%
Na-Z-Nw- (4-methoxy Benzene sulfonyl) -L-arginine dicyclohexylammonium salt 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Na-Z-Nw-nitro-L-arginine 99+% (HPLC)
Na-Z-Nw-nitro-L-arginine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences.
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Nb2AlC MAX phase ceramic material
Nb2AlC MAX phase ceramic material. Purity: ≥99%.
Nb2AlC (MAX) Phase Ceramic Material (400 mesh)
Nb2AlC (MAX) Phase Ceramic Material (400 mesh). Purity: ≥90%.
Nb2C MXene quantum dots
MXene quantum dots prepared by explosive method have stable performance. CAS No. 12011-99-3. Purity: 0.99.
Nb2CTx (MXene) Multilayer Nanoflake
Nb2CTx (MXene) Multilayer Nanoflake. CAS No. 12069-94-2. Purity: 40-50%.
Nb2CTx MXene porous foam
Nb2CTx MXene porous foam. CAS No. 12011-99-3. Purity: 0.99.
NB-3
NB-3 is a nicotinamide adenine dinucleotide (NAD) hydrolase SARM1 inhibitor. NB-3 intercepts NAD hydrolysis and undergoes covalent conjugation with the reaction product adenosine diphosphate ribose (ADPR). The resulting small-molecule ADPR adducts are highly potent and confer compelling neuroprotection in neurological injury[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3109123-46-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-171213.
Nb4AlC3 MAX phase ceramic material
Nb4AlC3 MAX phase ceramic material. Purity: ≥99%.
Nb4AlC3 (MAX) Phase Ceramic Material
Nb4AlC3 (MAX) Phase Ceramic Material. CAS No. 12069-94-2. Purity: ≥90%.
Nb4C3Tx (MXene) Multilayer Nanosheet
Nb4C3Tx (MXene) Multilayer Nanosheet. CAS No. 12069-94-2. Purity: ≥80%.
NB-598
NB-598 is a potent and competitive inhibitor of squalene epoxidase (SE), and suppresses triglyceride biosynthesis through the farnesol pathway. NB-598 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 131060-14-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16343.
NB-598 Maleate
NB-598 Maleate is a potent and competitive inhibitor of squalene epoxidase (SE), and suppresses triglyceride biosynthesis through the farnesol pathway. NB-598 (Maleate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 155294-62-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-16343C.
NB-7
NB-7 (example 12) is a potent and orally active SARM1 inhibitor with an IC50 < 1 μM. NB-7 can be used for neurological disorders research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2665712-31-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-203012.
NBD-556. Group: Biochemicals. Alternative Names: N1- (4-Chlorophenyl) -N2- (2, 2, 6, 6-tetramethyl-4-piperidinyl) ethanediamide. Grades: Highly Purified. CAS No. 333353-44-9. Pack Sizes: 5mg. Molecular Formula: C17H24ClN3O2, Molecular Weight: 337.84. US Biological Life Sciences.
Worldwide
NBD-557
NBD-557. Group: Biochemicals. Alternative Names: N1- (4-bromophenyl) -N2- (2, 2, 6, 6-tetramethyl-4-piperidinyl) ethanediamide. Grades: Highly Purified. CAS No. 333352-59-3. Pack Sizes: 5mg. Molecular Formula: C17H24BrN3O2, Molecular Weight: 382.3. US Biological Life Sciences.
Worldwide
NBD AA
Fluorescent NBD-AA and NBD-AEA analogues are direct probes that can be used for visualizing the uptake, intracellular trafficking, and targeting of these molecules by living cells, as well as measuring the binding of endocannabinoids to cytosolic binding proteins. Alternative Names: 20-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]arachidonic acid. Grades: >99%. CAS No. 2254005-15-5. Molecular formula: C26H34N4O5. Mole weight: 482.57.
NBD-amine. Alternative Names: 7-Amino-NBD,7-Amino-4-nitro-2,1,3-benzoxadiazole,7-Nitro-4-aminobenzofurazan,ABF. CAS No. 10199-91-4. Purity: 99%+. Product ID: ACM10199914-1. Molecular formula: C6H4N4O3. Mole weight: 180.12. IUPAC Name: 4-nitro-2,1,3-benzoxadiazol-7-amine. Alfa Chemistry - ISO 9001:32057 Certified.
NBD-C12-HPC
NBD-C12-HPC is a green-fluorescent analog of dodecanoyl glycerophosphocholine which is used for investigations of lipid trafficking in live cells. NBD-C12-HPC can be used in direct microscopy, fluorescence resonance energy transfer (FRET), and fluorescence recovery after photobleaching (FRAP) techniques. Alternative Names: 16:0-12:0 NBD PC; 1-palmitoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphocholine; 2-{[(2R)-2-{12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]dodecanoyloxy}-3-(1-hexadecanoyloxy)propoxy](hydroxy)phosphoryloxy}-N,N,N-trimethylethanaminium; (R)-2-((12-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)dodecanoyl)oxy)-3-(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate. Grades: 90%. CAS No. 105539-26-2. Molecular formula: C42H74N5O11P. Mole weight: 856.05.
NBD-C6-HPC
NBD-C6-HPC is a green-fluorescent hexanoyl glycerophosphocholic analog that is useful for investigation of lipid trafficking in live cells. Alternative Names: 2-(6-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl-1-hexadecanoyl-sn-glycero-3-phosphocholine. CAS No. 81005-34-7. Molecular formula: C36H62N5O11P. Mole weight: 771.89.
NBD cholesterol
NBD cholesterol is a lipophilic, membrane-permeant, green-fluorescent probe that is useful for investigations of lipid transport processes and lipid-protein interactions. Alternative Names: 22-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-23,24-bisnor-5-cholen-3-ol. CAS No. 78949-95-8. Molecular formula: C28H38N4O4. Mole weight: 494.63.
NBD-Cl
NBD-Cl is a nonfluorescent reagent which becomes highly fluorescent after reaction with thiol or amino groups[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NBD chloride. CAS No. 10199-89-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-D0042.
NBD-Cl
NBD-Cl. Uses: For analytical and research use. Alternative Names: 4-Chloro-7-nitro-2,1,3-benzoxadiazole; 4-Chloro-7-nitrobenzofurazan. CAS No. 10199-89-0. Molecular formula: C6H2ClN3O3. Mole weight: 199.55. Purity: >98.0%(T). Catalog: APB10199890-1.
NBD-COCl
NBD-COCl. Uses: For analytical and research use. Alternative Names: 4-(N-Chloroformylmethyl-N-methylamino)-7-nitro-2,1,3-benzoxadiazole. CAS No. 140164-85-8. Molecular formula: C9H7ClN4O4. Mole weight: 270.63. Purity: >92.0%(T). Catalog: APB140164858.
NBD-Fructose is a fluorescent derivative of Fructose (HY-N0395) that is formed by coupling NBD-chloride with the amine group of amino fructose (EX/Em=472/538 nm)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 940961-04-6. Pack Sizes: 500 μg; 1 mg. Product ID: HY-123067.
NBD-Fructose
NBD-Fructose is a fructose derivative that is formed by coupling NBD-chloride with the amine group of amino fructose. It has been used to monitor fructose uptake by the GLUT5 transporter in MCF-7, MDA-MB-435, and MDA-MB-231 human breast cancer cells. Alternative Names: 1-NBDF; 1-(7-nitro-1,2,3-benzadiazole)-Fructose; 1-deoxy-1-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-fructose. Grades: ≥95%. CAS No. 940961-04-6. Molecular formula: C12H14N4O8. Mole weight: 342.26.
N-b-D-Glucopyranosyl-L-Asn
N-b-D-Glucopyranosyl-L-Asn is an invaluable compound assuming a pivotal function in the precise targeting of discrete enzymes or receptors implicated in aberrant physiological mechanisms aiding in the research of afflictions encompassing cancer, inflammation and neurodegenerative maladies. Alternative Names: L-Asparagine, N-β-D-glucopyranosyl-; Asparagine, N-β-D-glucopyranosyl-, L-; N-β-D-Glucopyranosyl-L-asparagine; Glucopyranosylamine, N-β-aspartyl-; N-Glycosyl-L-asparagine; (2S)-2-amino-4-oxo-4-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]amino]butanoic acid. CAS No. 34234-60-1. Molecular formula: C10H18N2O8. Mole weight: 294.26.
Highly soluble nitric oxide donor, which is relatively stable at high pH (pH 8-9). Group: Biochemicals. Alternative Names: Glyco-SNAP-1. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
NBDHEX
NBDHEX is a potent glutathione S-transferase P1-1 (GSTP1-1) inhibitor. NBDHEX induces apoptosis of tumor cells. NBDHEX acts as an anticancer agent by inhibiting GSTs catalytic activity, avoiding inconvenience of the inhibitor extrusion from the cell by specific pumps and disrupting the interaction between the GSTP1-1 and key signaling effectors. NBDHEX can also act as late-phase autophagy inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 787634-60-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135318.
NBD hexanoic acid
NBD hexanoic acid. Group: Biochemicals. Alternative Names: 6-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoic acid; 6-[(7-Nitrobenzofurazan-4-yl)amino]hexanoic acid; 6-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]hexanoic acid; NBD-X. Grades: Highly Purified. CAS No. 88235-25-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C12H14N4O5. US Biological Life Sciences.
Worldwide
NBD Palmitic Acid
NBD Palmitic Acid, a vital tool in lipid metabolism research, is a fluorescent compound derived from palmitic acid. Widely employed to elucidate cellular fatty acid uptake mechanisms, it enables the examination of intricate pathways involved in lipid transport. Alternative Names: [16-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]palmitic acid; Hexadecanoic acid, 16-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-; 16-NBD palmitic acid. Grades: >99%. CAS No. 2260669-56-3. Molecular formula: C22H34N4O5. Mole weight: 434.53.
NBD-PE
NBD-PE is a cell-permeable, green-fluorescent phospholipid probe for investigation of membrane lipid mixing, lipid sorting and trafficking, and bilayer-to-hexagonal phase transitions. This probe is utilized in fluorescence recovery after photobleaching (FRAP), fluorescence resonance energy transfer to rhodamine fluorophores, and concentration-dependent self-quenching. CAS No. 178119-00-1. Molecular formula: C49H90N5O11P. Mole weight: 956.24.
NBD-PE
NBD-PE is an effective lipid fluorescent probe (Excitation/Emission: 465/535 nm; Color: Green). NBD-PE offers a wide array of applications in membrane and cell biology[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 178119-00-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-D1683.
NBD-Pen
NBD-Pen is the first fluorescence probe for lipid radicals with high selectivity and sensitivity (λex: 470 nm, λem: 530 nm). NBD-Pen specifically detects lipid derived radicals over other reactive species present in biological systems, including H2O2, ClO-, O2-?, and ?OH. NBD-Pen directly detects lipid radicals in living cells by turn-on fluorescence. NBD-Pen decreases inflammation, apoptosis, and oxidative stress markers. NBD-Pen can be studied in various disease models such as hepatic carcinoma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1955505-54-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-129109.
NBD peptide
NBD peptide inhibits NF-κB signaling pathway through inhibition of the NEMO-IKK complex combination. NBD peptide exhibits anti-inflammatory efficacy through block of pro-inflammatory cytokines production. NBD peptide exhibits immunosuppressive activity through regulation of immune cells. NBD peptide enhances its transmembrane ability by combining with cell-penetrating peptide HIV-TAT[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 371915-62-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10839.
NBD sphingosine is a sphingosine derivative that is tagged with a fluorescent group nitrobenzoxadiazole (NBD). It has been used to study the cellular localization and metabolism of sphingosine in HeLa cells. NBD sphingosine also inhibits proliferation of HCT116, PC3, HEK293T, and HFE-145 cells (IC50 = 25.6, 40.5, 10.4, and 12.5 μM, respectively). Alternative Names: omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol; D-erythro-Sphingosine-N-NBD. Grades: ≥95%. CAS No. 1449370-25-5. Molecular formula: C24H39N5O5. Mole weight: 477.60.
NBD-undecanoic acid
NBD-undecanoic acid. Alternative Names: 11-(7-Nitrobenzofurazan-4-ylamino)undecanoic acid. CAS No. 351002-77-2. Purity: 98%+. Product ID: ACM351002772-2. Molecular formula: C17H24N4O5. Mole weight: 364.4. Alfa Chemistry - ISO 9001:32057 Certified.
N-Benzoyl-2'-deoxy-2',2'-difluorocytidine is a potent antiviral compound used in the research of viral infections such as herpesviruses and poxviruses. With unique structure, this compound inhibits viral reproduction by interfering with viral DNA synthesis. Alternative Names: N6-Benzoyl-2'-deoxy-2',2'-diflurocytidine; 4-N-benzoylgemcitabine; N4-benzoyl-2'-deoxy-2',2'-difluorocytidine; N-Bz-Gemcitabine. Grades: ≥95%. CAS No. 142816-70-4. Molecular formula: C16H15F2N3O5. Mole weight: 367.30.
N-Benzoyl-2'-deoxy-2',2'-difluorocytidine 3'-Benzoate is an intermediate in the synthesis of Gemcitabine metabolites. Grades: 96%. CAS No. 1020657-43-5. Molecular formula: C23H19F2N3O6. Mole weight: 471.41.
N-Benzoyl-2'-deoxy-2',2'-difluorocytidine 3'-Benzoate 5'-(4-Methylbenzenesulfonate) is an intermediate in the synthesis of Gemcitabine metabolites. CAS No. 1151528-38-9. Molecular formula: C30H25F2N3O8S. Mole weight: 625.6.
N-Benzoyl-2'-deoxy-2'-fluoroadenosine, 3'-(hydrogen phosphonate), a compelling chemical compound extensively utilized in biomedicine, holds immense potential for addressing viral infections. Its remarkable efficacy in combating a diverse array of viral pathogens has been validated, owing to its distinct structure and mode of action. By impeding viral replication and propagation, this compound exhibits unprecedented antiviral activity. Consequently, it has the ability to revolutionize the landscape of antiviral drug development, presenting new avenues for combating viral diseases of varying origins. Alternative Names: SCHEMBL17325427; E71943; (2R,3R,4R,5R)-5-(6-BENZAMIDO-9H-PURIN-9-YL)-4-FLUORO-2-(HYDROXYMETHYL)TETRAHYDROFURAN-3-YL HYDROGEN PHOSPHONATE. CAS No. 1834500-64-9. Molecular formula: C17H16FN5O6P+. Mole weight: 436.3.
N-Benzoyl-2'-deoxy-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-2',2'-difluorocytidine 3'-Benzoate is an intermediate in the synthesis of Gemcitabine metabolites. CAS No. 1151528-37-8. Molecular formula: C29H33F2N3O6Si. Mole weight: 585.67.
N-Benzoyl-2'-deoxy-5'-O-trityladenosine
N-Benzoyl-2'-deoxy-5'-O-trityladenosine is a chemical compound used in biomedical research as a reference standard for the testing and development of nucleoside analogues. It has been shown to have potential in the treatment of viral infections and cancer due to its ability to inhibit RNA synthesis. Studies have also suggested its potential use in gene therapy due to its ability to penetrate cell membranes and deliver genetic material. Alternative Names: 5'-Trt-N6-Bz-2'-dA; 5'-O-Trt-N6-Bz-dA; N-Benzoyl-2'-deoxy-5'-O-(triphenylmethyl)-Adenosine; Adenosine, N-benzoyl-2'-deoxy-5'-O-(triphenylmethyl)-. Grades: ≥98% by HPLC. CAS No. 75759-62-5. Molecular formula: C36H31N5O4. Mole weight: 597.67.
N-Benzoyl-(2R,3S)-3-phenylisoserine
N-Benzoyl-(2R,3S)-3-phenylisoserine is a Taxol C-13 Side Chain and crucial for the strong antitumor activity of Taxol[1]. Uses: Scientific research. Category: Natural products. CAS No. 132201-33-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2380.
N-Benzoyl-(2R,3S)-3-phenylisoserine
An impurity of Paclitaxel which is a chemotherapy medication. Alternative Names: (2R,3S)-N-Benzoyl-3-phenyl Isoserine; (αR,βS)-β-(Benzoylamino)-α-hydroxybenzenepropanoic Acid; [R-(R*,S*)]-β-(benzoylamino)-α-hydroxybenzenepropanoic Acid; (2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropionic Acid; (2R,3S)-N-Benzoyl-3-phenylisoserine. Grades: 98%. CAS No. 132201-33-3. Molecular formula: C16H15NO4. Mole weight: 285.3.
N-Benzoyl-(2R,3S)-3-Phenylisoserine Methyl ester
N-Benzoyl-(2R,3S)-3-Phenylisoserine Methyl ester. CAS No. 32981-85-4. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Involved in the biosynthesis of phytoalexins. Group: Enzymes. Synonyms: N-benzoyl-4-hydroxyanthranilate 4-methyltransferase; benzoyl-CoA:anthranilate N-benzoyltransferase. Enzyme Commission Number: EC 2.1.1.105. CAS No. 125498-68-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1703; N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase; EC 2.1.1.105; 125498-68-2; N-benzoyl-4-hydroxyanthranilate 4-methyltransferase; benzoyl-CoA:anthranilate N-benzoyltransferase. Cat No: EXWM-1703.
N-Benzoyl-4-nitroaniline ethyl ester
N-Benzoyl-4-nitroaniline ethyl ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 58816-69-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C18H18N2O5. US Biological Life Sciences.
N-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It features a benzoyl group protecting the adenine base, a 5'-dimethoxytrityl (DMT) group for 5'-hydroxyl protection, a 2'-O-methyl group to enhance stability, and a cyanoethyl (CE) group on the 3'-phosphoramidite for protection during synthesis. These modifications facilitate the incorporation of modified adenosine into oligonucleotides, improving their stability and performance in various applications such as genetic research and therapeutic development. Alternative Names: N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite; Dmt-2'-O-me-ra(bz) amidite; 2'-O-Methyl-rA(N-Bz)phosphoramidite; DMT-2'O-Methyl-rA(bz) Phosphoramidite; 5'-O-DMT-2'-O-Me-A(bz) phosphoramidite; 2'-OMe-Bz-A-CE-Phosphoramidite; N6-Benzoyl-5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-Adenosine-3'-CE-Phosphoramidite. Grades: ≥98% by HPLC. CAS No. 110782-31-5. Molecular formula: C48H54N7O8P. Mole weight: 887.96.
N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a classic protected 2-OTBDMS phosphoramidite used to incorporate nucleoside A into the synthesis of oligonucleotides. Alternative Names: Bz-rA Phosphoramidite; DMT-2'O-TBDMS-rA(Bz) Phosphoramidite; 5'-O-DMT-2'-O-tert-Butyldimethylsiyl-N6-Benzoyl-adenosine 3'-CE phosphoramidite; N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 3'-CE phosphoramidite; 5'-O-DMT-2'-O-TBDMS-rA(Bz) 3'-CE phosphoramidite; DMT-2'-O-TBDMS-A(Bz)-CE-Phosphoramidite; N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-adenosine-3'-cyanoethyl Phosphoramidite. Grades: ≥98% by HPLC. CAS No. 104992-55-4. Molecular formula: C53H66N7O8PSi. Mole weight: 988.22.
N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-adenosine is a commonly used reactant in the preparation of nucleosidic phosphoramidite derivatives. Alternative Names: N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)adenosine; N-(9-((2R,3R,4R,5R)-5-((bis(4-Methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-adenosine; 2'-O-MOE-5'-O-DMT-A(Bz); 5'-O-DMT-2'-O-MOE-N6-Bz-rA. Grades: ≥95%. CAS No. 251647-48-0. Molecular formula: C41H41N5O8. Mole weight: 731.79.
N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]cytidine is a chemical compound used in the synthesis of oligonucleotides. This compound features a cytidine nucleoside that has been modified with a benzoyl (bz) group protecting the amino group at the N4 position and a bis(4-methoxyphenyl)phenylmethyl (commonly known as dimethoxytrityl or DMT) group protecting the 5' hydroxyl position. These protective groups prevent unwanted side reactions during the stepwise assembly of nucleotide chains in automated DNA or RNA synthesis, ensuring efficient and precise production of oligonucleotides. This reagent is essential for various applications in molecular biology, genetic research, and the development of nucleic acid-based therapeutics. Alternative Names: 5'-DMT Cytidine (n-bz); 5'-O-(4,4'-Dimethoxytrityl)-N4-benzoylcytidine; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-; N-(1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide; N-Benzoyl-5'-O-(4,4'-dimethoxytrityl)cytidine; N4-Benzoyl-5'-O-DMT-D-cytidine; N-Benzoyl-5'-(di-p-methoxytrityl)cytidine. Grades: ≥95%. CAS No. 81246-76-6. Molecular formula: C37H35N3O8. Mole weight: 649.69.