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| Product | Description | |
|---|---|---|
| PF-562271 | Potent ATP-competitive reversible inhibitor of FAK and Pyk2. PF-562,271 is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 catalytic activity with a IC(50) of 1.5 and 14nm, respectively. In addition, PF-562,271 displayed robust inhibition in an inducible cell-based assay measuring phospho-FAK with an IC(50) of 5nm. PF-562,271 was evaluated against multiple kinases and displays >100X selectivity against a long list of non target kinases. In tests, PF-562,271 inhibits FAK phosphorylation in vivo in a dose-dependent fashion with a calculated EC50 of 93ng/ml using injections. Group: Biochemicals. Grades: Highly Purified. CAS No. 717907-75-0. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C21H20F3N7O3S, Target: FGFR. US Biological Life Sciences. |  Worldwide |
| PF-562271 hydrochloride | PF-562271 (VS-6062) hydrochloride is a potent, ATP-competitive and reversible FAK and Pyk2 kinase inhibitor with IC50s of 1.5 nM and 13 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VS-6062hydrochloride. CAS No. 939791-41-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg. Product ID: HY-20403. |  |
| PF-573228 | PF-573228 is a potent and selective FAK inhibitor with IC50 of 4 nM for purified recombinant catalytic fragment of FAK. Uses: Scientific research. Category: Signaling pathways. CAS No. 869288-64-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10461. | |
| PF-573228 | PF-573228 Inhibitor. Uses: Scientific use. Product Category: T2001. CAS No. 869288-64-2. |  |
| PF-573228 | PF-573228 is an ATP-competitive inhibitor of FAK with IC50 of 4 nM in a cell-free assay, ~50- to 250-fold selective for FAK than Pyk2, CDK1/7 and GSK-3β. PF-573228 induces apoptosis. Group: Inhibitors. CAS No. 869288-64-2. Pack Sizes: 10mg. Product ID: S2013. Formula: C22H20F3N5O3S. Smiles: CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)CC4. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| PF-573228 | A novel focal adhesion kinase inhibitor that has been shown to suppress the adverse phenotype of endocrine-resistant breast cancer cells and improve endocrine response in endocrine-sensitive cells. Group: Biochemicals. Alternative Names: 3, 4-Dihydro-6-[[4-[[[3- (methylsulfonyl) phenyl]methyl]amino]-5- (trifluoromethyl) -2-pyrimidinyl]amino]-2 (1H) -quinolinone; 6- [ (4- ( (3- (Methanesulfonyl) benzyl) amino) -5-trifluoro methyl pyrimidin-2-yl) amino] -3, 4-dihydro-1H-quinolin-2-one; PF 573228. Grades: Highly Purified. CAS No. 869288-64-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PF 670462 | PF 670462. Group: Biochemicals. Grades: Purified. CAS No. 950912-80-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PF-670462 | PF-670462 is a potent and selective inhibitor of CK1ε in isolated enzyme preparations. It inhibits PER protein nuclear translocation causing phase shifts in circadian rhythms and attenuates methamphetamine-stimulated locomotion in vivo. It less effectively inhibits a wide variety of related or common kinases. It disrupts circadian rhythms in cells and animals and blocks the locomotor response to amphetamines in mice. It remains unclear whether one of the kinases has a predominant role in regulating the circadian clock. Alternative Names: PF-670462; PF 670462; PF670462;PF-670462 HCl; PF-670462 hydrochloride. Grades: >98%. CAS No. 950912-80-8. Molecular formula: C19H22Cl2FN5. Mole weight: 410.32. |  |
| PF-670462 dihydrochloride | PF-670462 dihydrochloride is a potent and selective inhibitor of casein kinase (CK1ε and CK1δ), with IC50s of 7.7 nM and 14 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 950912-80-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15490. | |
| PF-739 | PF-739 is an orally active and non-selective activator of AMPK. PF-739 activates 12 heterotrimeric AMPK complexes and significantly reduces the level of glucose in plasma complexes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1852452-14-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117755. | |
| PF 750 | Fatty acid amide hydrolase (FAAH) inhibitor, selectively inhibiting FAAH within the central nervous system. Group: Biochemicals. Alternative Names: N-Phenyl-4-(3-quinolinylmethyl)-1-piperidinecarboxamide; N-Phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide. Grades: Highly Purified. CAS No. 959151-50-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PF 8380 | PF 8380. Group: Biochemicals. Grades: Purified. CAS No. 1144035-53-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PF-8380 | PF-8380 is a potent autotaxin inhibitor with an IC50 of 2.8 nM in isolated enzyme assay and 101 nM in human whole blood. Uses: Scientific research. Category: Signaling pathways. CAS No. 1144035-53-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13344. | |
| PF-8380 | PF-8380 blocks inflammation-induced LPA synthesis. PF-8380 works both in vitro and in vivo through direct inhibition of autotaxin. In human whole blood PF-8380 inhibited autotaxin with an IC50 of 101 nM. Inhibition of ATX by PF-8380 led to decreased invasion and enhanced radiosensitization of GBM cells. Radiation-induced activation of Akt was abrogated by inhibition of ATX. Furthermore, inhibition of ATX led to diminished tumor vascularity and delayed tumor growth. PF-8380 can serve as a tool compound for elucidating LPA's role in inflammation. Alternative Names: 1-Piperazinecarboxylic acid, 4-[3-(2,3-dihydro-2-oxo-6-benzoxazolyl)-3-oxopropyl]-, (3,5-dichlorophenyl)methyl ester; PF8380; PF 8380; (3,5-Dichlorophenyl)methyl 4-[3-(2,3-dihydro-2-oxo-6-benzoxazolyl)-3-oxopropyl]-1-piperazinecarboxylate; 4-[3-Oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]piperazine-1-carboxylic acid 3,5-dichlorobenzyl ester. Grades: ≥95%. CAS No. 1144035-53-9. Molecular formula: C22H21Cl2N3O5. Mole weight: 478.33. | |
| PF-8380 hydrochloride | PF-8380 hydrochloride is a potent autotaxin inhibitor with an IC50 of 2.8 nM in isolated enzyme assay and 101 nM in human whole blood. Uses: Scientific research. Category: Signaling pathways. CAS No. 2070015-01-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13344A. | |
| PF 915275 | PF 915275. Group: Biochemicals. Grades: Purified. CAS No. 857290-04-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PF-915275 | PF-915275 is a potent, selective and orally active human 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor with a Ki of 2.3 nM and an EC50 of 15 nM (in HEK293 cells). The dose-dependent effect of PF-915275 on conversion of cortisone to cortisol in primary human and monkey hepatocytes, with an EC50 of 20 and 100 nM, respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 857290-04-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18056. | |
| PF-9363 | PF-9363 is a first-in-class inhibitor of KAT6A/KAT6B. PF-9363 exhibits potent anti-tumor activity in several ER+ breast cancer cell lines. Alternative Names: CTx-648; CTX-3648; 2,6-dimethoxy-N-{4-methoxy-6-[(1H-pyrazol-1-yl)methyl]-1,2-benzoxazol-3-yl}benzene-1-sulfonamide. Grades: 98%. CAS No. 2569009-58-9. Molecular formula: C20H20N4O6S. Mole weight: 444.46. | |
| PF-9363 | PF-9363 (CTx-648) is a first-in-class potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CTx-648. CAS No. 2569009-58-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132283. | |
| PF-9366 | PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor, with an IC50 of 420 nM and a Kd of 170 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 72882-78-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107778. | |
| PF9 tetrasodium salt | PF9 tetrasodium salt. Group: Biochemicals. Grades: Purified. CAS No. 851265-78-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| PFB-FDGlu | PFB-FDGlu is a selective lysosomal Glucocerebrosidase (GCase) substrate, which is metabolised by GCase to yield fluorescein. PFB-FDGlu is cell permeable and can be used with a flow cytometer to measure GCase activity in living cells on a single-cell basis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 209540-62-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139452. | |
| PFD | PFD. Alternative Names: Poly(9,9-di-n-dodecylfluorene). CAS No. 248256-53-3. |  |
| PfDHODH-IN-1 | PfDHODH-IN-1, an analogue of the active Leflunomide metabolite, exhibits antimalarial activity. Category: Active pharmaceutical ingredients. CAS No. 183945-55-3. Product ID: API183945553. Molecular formula: C14H11F3N2O2. Mole weight: 296.24. |  |
| PF-DMB | PF-DMB. Alternative Names: PF-DMB;Poly[(9,9-dihexylfluoren-2,7-diyl)-alt-(2,5-dimethyl-1,4-phenylene)]. CAS No. 579505-48-9. Purity: 96%. | |
| PFE-360 | PFE-360 (PF-06685360) is a potent, selective, brain penetrated and orally active leucine-rich repeat kinase 2 (LRRK2) inhibitor with a mean IC50 of 2.3 nM in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-06685360. CAS No. 1527475-61-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120085. | |
| PFE-360 | PFE-360 Inhibitor. Uses: Scientific use. Product Category: T16512. CAS No. 1527475-61-1. | |
| PffBT4T-2OD | Band gap: 1.65 eV. Alternative Names: PCE-11,Poly[(5,6-difluoro-2,1,3-benzothiadiazol-4,7-diyl)-alt-(3,3'''-di(2-octyldodecyl)-2,2',5',2'',5'',2'''-quaterthiophen-5,5'''-diyl)]. CAS No. 1644164-62-4. Molecular formula: (C62H88F2N2S5)n. | |
| PffBT4T-C9C13 | PffBT4T-C9C13. | |
| PFI-1 | PFI-1, a chemical probe, is a selective BET (bromodomain-containing protein) inhibitor for BRD4 with IC50 of 0.22 μM in a cell-free assay. Uses: Scientific research. Category: Signaling pathways. CAS No. 1403764-72-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16586. | |
| PFI-1 | PFI-1. Group: Biochemicals. Alternative Names: 2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide; 2-Methoxy-N- (1, 2, 3, 4-tetrahydro-3-methyl-2-oxo-6-quinazolinyl) benzenesulfonamide. Grades: Highly Purified. CAS No. 1403764-72-6. Pack Sizes: 5mg. Molecular Formula: C16H17N3O4S, Molecular Weight: 347.39. US Biological Life Sciences. | Worldwide |
| PFI-2 | PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride, a chemical probe, is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0 nM and (S)-PFI-2 shows inhibiting activity with IC50 value of 1.0 μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-PFI-2. CAS No. 1627676-59-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18627. | |
| PFI-2 hydrochloride | PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0??nM and (S)-PFI-2 shows inhibiting activity with IC50 ?value of?1.0??μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-PFI-2 hydrochloride. CAS No. 1627607-87-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-18627A. | |
| PFI-2 hydrochloride | PFI-2 hydrochloride is a potent, cell-permeable inhibitor of SET7/9 (IC50 = 2 nM) and is approximately 1,000-fold selective over a panel of 18 other methyltransferases. Besides, following activation of the Hippo signaling pathway in MCF7 cells it inhibits. Alternative Names: PFI-2 hydrochloride; PFI 2 hydrochloride; PFI2 hydrochloride; 8-fluoro-N-[(2R)-1-oxo-1-pyrrolidin-1-yl-3-[3-(trifluoromethyl)phenyl]propan-2-yl]-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide;hydrochloride. CAS No. 1627607-87-7. Molecular formula: C23H26ClF4N3O3S. Mole weight: 535.98. | |
| PFI-2 Hydrochloride | PFI-2 Hydrochloride. Alternative Names: PFI-2; PFI2; PFI 2; (R)-PFI-2; (R)-PFI-2 hydrochloride. PFI-2 hydrochloride. CAS No. 1627607-87-7. Purity: ≥98%. Product ID: ACM1627607877. Molecular formula: C23H26ClF4N3O3S. Mole weight: 535.9826 g/mol. IUPAC Name: (R)-8-fluoro-N-(1-oxo-1-(pyrrolidin-1-yl)-3-(3-(trifluoromethyl)phenyl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide hydrochloride. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| PFI-3 | PFI-3, a chemical probe, is a selective, potent and cell-permeable SMARCA2/4 bromodomain inhibitor with a Kd of 89 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1819363-80-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12409. | |
| PFI-3 | PFI-3, a potent and selective SMARCA2/4 bromodomain inhibitor, is a cell-permeable probe that binds avidly to the structurally-similar SMARCA4 bromodomain (Kd= 89 nM) and PB1(bromodomain 5) (Kd= 48 nM). Alternative Names: PFI-3; PFI 3; PFI3. (E)-1-(2-hyd roxyphenyl)-3-[(1R,4R)-2-pyridin-2-yl-2,5-diazabicyclo[2.2.1]heptan-5-yl]prop-2-en-1-one; PF-06687252; PFI-3 compound; PF 06687252; PF06687252. Grades: >98%. CAS No. 1819363-80-8. Molecular formula: C19H19N3O2. Mole weight: 321.38. | |
| PFI-6 | PFI-6 is a selective MLLT1 and MLLT3 YEATS domain probe with IC50 values of 0.14 μM and 0.16 μM, respectively. PFI-6 is applicable for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2675452-91-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg. Product ID: HY-155412. | |
| PFI-90 | PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action. PFI-90 induces apoptosis and myogenic differentiation, resulting in the cell death increased. PFI-90 has the potential for the antitumor activity. (patent WO2021101929A1). Uses: Scientific research. Category: Signaling pathways. CAS No. 53995-62-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-139348. | |
| PFI-90 | PFI-90 is a selective inhibitor of the histone demethylase KDM3B. PFI-90 was shown to induce apoptosis and cell differentiation, resulting in tumor cell death. Alternative Names: N'-(pyridin-2-yl)pyridine-2-carbohydrazide; 2-Pyridinecarboxylic acid, 2-(2-pyridinyl)hydrazide. Grades: 98%. CAS No. 53995-62-3. Molecular formula: C11H10N4O. Mole weight: 214.22. | |
| PFIID | PFIID. CAS No. 2019220-88-1. Molecular formula: (C85H128N2O2)n. | |
| PFK-015 | PFK-015, a derivative of 3PO, is a specific PFKFB3 inhibitor. PFK-015 inhibits recombinant PFKFB3 with an IC50 value of 110 nM and inhibits PFKFB3 activity in cancer cells with an IC50 value of 20 nM. PFK-015 can be used for the research of multiple cancers such as lung cancer, stomach cancer, colon cancer and esophageal squamous cell carcinoma (ESCC)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4382-63-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12204. | |
| PFK15 | PFK15 is a potent and selective inhibitor of 6-phosphofructo-2-kinase (PFKFB3) with IC50 of 207 nM. Overexpression of the PFKFB3 enzyme leads to high glycolytic metabolism, which is required for cancer cells to survive in the harsh tumor microenvironment. Alternative Names: PFK 015; PFK015; 1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one. Grades: >98%. CAS No. 4382-63-2. Molecular formula: C17H12N2O. Mole weight: 260.29. | |
| PFK-158 | PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase / fructose-2,6-bisphosphatases (PFK-2 / FBPase) isoform 3 (PFKFB3) and derivative of 3-(3-pyridinyl)-1-[4-pyridinyl]-2-propen-1-one (3PO), with potential antineoplastic activity. Upon administration, PFKFB3 inhibitor PFK-158 binds to and inhibits the activity of PFKFB3, which leads to the inhibition of both the glycolytic pathway in and glucose uptake by cancer cells. This prevents the production of macromolecules and energy that causes the enhanced cellular proliferation in cancer cells as compared to that of normal, healthy cells. Depriving cancer cells of nutrients and energy leads to the inhibition of cancer cell growth. PFKFB3, an enzyme that catalyzes the conversion of fructose-6-phosphate to fructose-2,6-bisphosphate, is highly expressed and active in human cancer cells; it plays a key role in increasing both glycolytic flux in and proliferation of cancer cells. Alternative Names: PFK158; PFK 158; PFK158; ACTPFK158. Grades: >98%. CAS No. 1462249-75-7. Molecular formula: C18H11F3N2O. Mole weight: 328.29. | |
| PFK-158 | PFK-158 is a potent and selective PFKFB3 inhibitor with an IC50 value 137 nM. PFK-158 reduces glucose uptake, ATP production, lactate release, and induces apoptosis and autophagy in cancer cells. PFK-158 has broad anti-tumor activity. PFK-158 can also enhance Colistin's resistance to bacteria[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1462249-75-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12203. | |
| PFKFB4-IN-1 | PFKFB4-IN-1 is a potent and selective ATP-competitive PFKFB4 inhibitor (IC50 = 4.50 μM) that reduces intracellular PFKFB4 protein levels. PFKFB4-IN-1 exhibits >12-fold selectivity over PFKFB1/4 and PFKFB3/4. PFKFB4-IN-1 inhibits cancer cell proliferation, induces apoptosis, and inhibits cell migration. PFKFB4-IN-1 inhibits tumor growth in the MDA-MB-231 xenograft mouse model. PFKFB4-IN-1 can be used for breast, lung and liver cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2664831-55-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-178367. | |
| p-Fluoropropiophenone | p-Fluoropropiophenone. Group: Biochemicals. Grades: Highly Purified. CAS No. 456-03-1. Pack Sizes: 50g, 100g. US Biological Life Sciences. | Worldwide |
| p-Fluorostyrene | p-Fluorostyrene. Alternative Names: 4-Fluorostyrene, 97%, stabilized; AS03795; ST2403438; RTR-033260; 4-Fluorostyrene, 99%; AN-44804; 405-99-2; ACN-S004611; CTK3J0456; I01-7785. CAS No. 405-99-2. Molecular formula: C8H7F. Mole weight: 122.142g/mol. IUPAC Name: 1-ethenyl-4-fluorobenzene. SMILES: C=CC1=CC=C(C=C1)F. InChI: InChI=1S/C8H7F/c1-2-7-3-5-8(9)6-4-7/h2-6H,1H2. | |
| PFM01 | PFM01, N-alkylated Mirin derivative, is a MRE11 endonuclease inhibitor. PFM01 can regulate double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) versus homologous recombination (HR)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1558598-41-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-116770. | |
| PFM39 | PFM39, a Mirin analog, is a potent and selective MRE11 exonuclease inhibitor. PFM39 inhibits phosphate rotation for dsDNA exonuclease activity. PFM39 does not inhibit TmMre11 or human MRE11/MRN endonuclease activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1310744-67-2. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120951. | |
| Pfn1-IN-1 | Pfn1-IN-1 (compound C1) is a Pfn1 inhibitor that inhibits the angiogenic capacity of endothelial cells (EC). Pfn1 is a regulator of the actin cytoskeleton, inducing actin polymerization and essential cellular activities. Pfn1-IN-1 inhibits Pfn1-Actin interaction and Actin polymerization. Uses: Scientific research. Category: Signaling pathways. CAS No. 919010-46-1. Pack Sizes: 1 mg. Product ID: HY-136808. | |
| PFN-Br | PFN-Br is a solution processible, conjugated polymer electrolyte used as interficial layer in high performance organic photovoltaic cells (OPV) and organic light emitting diodes (OLED) to improve the interfacial properties.OPV devices with PFN-Br interfacial layer showed overall enhanced short-circuit current density, open-circuit voltage, fill factor and corresponding high efficiency in the inverted OPVs. This was attributed to the good contact between ZnO electron extraction layer and the active layer, good interface adhesion between the electron extraction layer and active layer, and enhanced charge transport via suppressed bimolecular recombination. Recent report of OPV with a record energy conversion efficiency of 17.3% also utilized PFN-Br, spin-coated on top of ZnO to improve the interfacial properties.Tandem Cell Device performance:ITO/ZnO/PFN-Br / PBDB-T:F-M/M-PEDOT/ZnO/PTB7- Th:O6T-4F:PC71BM/MoO3/Ag Voc=1.642 VJsc=14.35 mA/cm2FF=73.7% PCE=17.3% PFN-Br finds application in a wide range of areas: OPV interficial layer (metalic oxide compact layer) OLED electron transport layer Perovskite solar cells Flexible printed electronics Cationic polymer electrolyte Anion exchange material Light emitting electrochemical cells. Alternative Names: OS0995,PFN-P2,PFN-bromide, PFNBr, Poly(9,9-bis(3'-(N,N-dimethyl)-N-ethylammoinium-propyl-2,7-fluorene)-alt-2,7-(9,9-dioctylfluorene))dibromide. CAS No. 889672-99-5. Molecular formula: (C56H8 | |
| PFN-DOF | Phosphorescent host material. Polymer for use in electron transport layer in OPV and OLED applications. Alternative Names: Poly[(9,9-bis(3'-(N,N-dimethylamino)propyl)-2,7-fluorene)-alt-2,7-(9,9-dioctylfluorene)]. CAS No. 673474-75-4. Molecular formula: (C52H70N2)n. | |
| PFO-DBT | PFO-DBT. | |
| PFQa-St2 | PFQa-St2 is an antimicrobial peptide found in the African clawed frog Silurana tropicalis, and has anti-gram-positive bacteria, gram-negative bacteria and Mammalian cells activity. Alternative Names: Phe-Ile-Gly-Ala-Leu-Leu-Arg-Pro-Ala-Leu-Lys-Leu-Leu-Ala-Gly-Lys. Grades: ≥97%. Molecular formula: C81H141N21O17. Mole weight: 1681.15. | |
| Pfu DNA Polymerase | Pfu DNA Polymerase is an important enzyme in PCR-related experiments, which is initially found in Pyrococcus furiosus. Pfu DNA Polymerase exhibits thermostability and high fidelity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2304873-45-6. Pack Sizes: 100 U. Product ID: HY-E70376. | |
| Pfu DNA Polymerase | Pfu DNA Polymerase. Pfu dna polymerase is a fast, high fidelity and high processivity hot start dna polymerase. extension rate is about 2-4 kb/min. amplification of genomic dna fragment up to 15 kb. amplification of plasmid dna fragment up to 20 kb. Group: Cloning Enzymes. Purity: 250U; 500U. Storage: Store at -20 ?. Cat No: CE-3015. |  |
| PG01 | PG01 is a potent CFTR Cl- channel potentiator. PG01 can correct gating defects of CFTR mutants, is effective on b>E193K, G970R and G551D (CFTR mutants) with Kd values of 0.22 μM, 0.45 μM and 1.94 μM, respectively. PG01 is also effective on ΔF508 (Ka of 0.3 μM). PG01 increases ΔF508-CFTR Cl- current after adding Forskolin[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 853138-65-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103369. | |
| PG 01 | PG 01. Group: Biochemicals. Grades: Purified. CAS No. 853138-65-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PG 01037 dihydrochloride | PG 01037 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 675599-62-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PG 106 | PG 106 is a selective human melanocortin receptor 3 (hMC3R) antagonist (IC50 = 210 nM), with no activity at hMC4 receptors and hMC5 receptors. PG 106 may be used to differentiate the substructural features responsible for selectivity at the hMC3R, hMC4R, and hMC5R. Alternative Names: PG106; PG-106; Ac-DL-Nle-Asp(1)-bAla-D-2Nal-Arg-Trp-Lys(1)-NH2; N-Acetyl-L-norleucyl-L-α-aspartyl-β-alanyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophyl-L-Lysinamide(2→7)-lactam; Ac-Nle-cyclo(-Asp-β-Ala-D-2-Nal-Arg-Trp-Lys)-NH2. Grades: >98%. CAS No. 944111-22-2. Molecular formula: C51H69N13O9. Mole weight: 1008.19. | |
| PG-11047 tetrahydrochloride | PG-11047 (CGC-11047), a polyamine analogue, is a nonfunctional competitor of the natural polyamine spermine. PG-11047 has broad spectrum anticancer activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CGC-11047 tetrahydrochloride. CAS No. 206991-64-2. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-16394. | |
| pG(2',5')pA | pG(2',5')pA is a potential metabolite of 2'3'-cGAMP, the metazoan cyclic dinucleotide second messenger. Alternative Names: 5'- Phosphoguanylyl- (2' -≥ 5')- adenosine, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 55779-55-0. Molecular formula: C20H26N10O14P2. Mole weight: 692.4. | |
| PG 931 | PG 931. Group: Biochemicals. Grades: Purified. CAS No. 667430-81-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| PG 97-269 | PG 97-269, a selective high affinity VPAC1 receptor antagonist, has negligible affinity for PACAP type I receptors, with Kis of 15±5 and 2±1 nM for the rat and human VPAC1 receptors, respectively. It can be used to evaluate the physiological role of VIP in rats and human tissues. Alternative Names: Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27); Ac-His-D-Phe-Asp-Ala-Val-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Lys-Arg-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-NH2; L-Leucinamide, N-acetyl-L-histidyl-D-phenylalanyl-L-α-aspartyl-L-alanyl-L-valyl-L-phenylalanyl-L-threonyl-L-asparaginyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-L-lysyl-L-arginyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-isoleucyl-. Grades: ≥95%. CAS No. 202463-00-1. Molecular formula: C150H246N44O38. Mole weight: 3273.83. | |
| PG-9 maleate | PG-9 maleate. Group: Biochemicals. Grades: Purified. CAS No. 155649-00-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PGA | CD Bioparticles provides PGA, Poly(glycolide)s with a PGA molecular weight of Mw ~ 1,000 -5,000 Da for drug delivery. Group: Poly(glycolide)s. |  |
| PGACL | CD Bioparticles provides PGACL, Poly(glycolide-co-caprolactone)s with a monomer ratio of CL:GA 85:15 for drug delivery. Group: Poly(glycolide-co-caprolactone)s. | |
| PgAFP | PgAFP is an antimicrobial peptide found in Penicillium chrysogenum RP42C (Penicillium notatum), and has antifungal activity. Alternative Names: Antifungal protein; afp. Grades: >98%. Molecular formula: C272H431N89O85S6. Mole weight: 6500.32. | |
| PGAM1-IN-1 | PGAM1-IN-1 is a phosphoglycerate mutase 1 (PGAM1) inhibitor with an IC50 of 6.4 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2438637-65-9. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-128681. | |
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