A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
A cell-permeable, PLD1/2 inhibitor (IC50=1nM and 10nM for PLD1 and PLD2, respectively, in a CHO cell based assay, and IC50=20nM for PLD2 in a biochemical assay), that displays no activity toward MitoPLD, and is selective for PLD1 and PLD2 over other PLD superfamily enzymes. It is also shown to block PLD2-dependent effects on cytoskeletal reorganization and cell trafficking in CHO cells, and diminish fMLP-directed neutrophil chemotaxis in HL60 cells at 750nM. Unlike 1-butanol, this compound does not affect glucose-stimulated insulin secretion in Min6 pancreatic b-cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??FN?O?, Molecular Weight: 421.2. US Biological Life Sciences.
Worldwide
Ple19 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (HindIII-digest) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 100U; 500U. CGAT↑CG GC↓TAGC. Activity: 2000-5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Pseudomonas lemoignei 19. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1148RE.
Plecanatide
Plecanatide, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide shows anti-inflammatory activity in models of murine colitis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 467426-54-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-108741.
Plecanatide
Plecanatide, also called Trulance, a synthetic analogue of uroguanylin, is a guanylate cyclase-C (GCC) agonist being developed by Synergy Pharmaceuticals for the treatment of gastrointestinal disorders, such as chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). In January 2017, an oral formulation of plecanatide received its first global approval in the USA for the treatment of adult patients with CIC. Besides, Plecanatide is undergoing phase III investigation in IBS-C. It had also undergone preclinical investigations in inflammatory bowel disease (IBD) and ulcerative colitis; however, development in these indications has been discontinued. Uses: Guanylyl cyclase c agonists; gastrointestinal agents. Synonyms: L-Leucine, L-asparaginyl-L-α-aspartyl-L-α-glutamyl-L-cysteinyl-L-α-glutamyl-L-leucyl-L-cysteinyl-L-valyl-L-asparaginyl-L-valyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (4→12)?,?(7→15)?-bis(disulfide); 105: PN: WO2012037380 SEQID: 105 claimed protein; 1: PN: US20100152118 SEQID: 1 claimed protein; 1: PN: WO2008151257 SEQID: 1 claimed protein; 1: PN. CAS No. 467426-54-6. Molecular formula: C65H104N18O26S4. Mole weight: 1681.89.
Plecanatide acetate
Plecanatide acetate, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide acetate activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide acetate can be used for the research of chronic idiopathic constipation, and it also shows anti-inflammatory activity in models of murine colitis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1075732-84-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108741A.
Pleconaril
Pleconaril is a picornavirus capsid binding inhibitor that prevents attachment and/or virus uncoating. Pleconaril has potential for use in rhinoviruses and enteroviruses research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VP 63843; Win 63843. CAS No. 153168-05-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-19952.
Pleconaril
Picornavirus replication inhibitor. Antiviral. Group: Biochemicals. Alternative Names: 3-[3, 5-Dimethyl-4-[3- (3-methyl-5-isoxazolyl) propoxy]phenyl]-5- (trifluoromethyl) -. Grades: Highly Purified. CAS No. 153168-05-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Plectasin
Plectasin is an antibiotic protein from the mushroom Pseudoplectania nigrella. It belongs to the antimicrobial peptide class called fungal defensins. It has antibacterial activity. Grade: >98%. CAS No. 676464-91-8. Molecular formula: C189H273N53O56S7. Mole weight: 4407.99.
P-LENE 4 polypropylene 3D printing filament
P-LENE 4 polypropylene 3D printing filament.
Plerixafor
Plerixafor (AMD 3100) is a selective CXCR4 antagonist with an IC50 of 44 nM. Plerixafor, an immunostimulant and a hematopoietic stem cell (HSC) mobilizer, is an allosteric agonist of CXCR7. Plerixafor inhibits HIV-1 and HIV-2 replication with an EC50 of 1-10 nM[1][2][3][4][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMD 3100; JM3100; SID791. CAS No. 110078-46-1. Pack Sizes: 10 mM * 1 mL in Ethanol; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-10046.
Plerixafor
100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C28H54N8. CAS No. 110078-46-1. Prepack ID 59191723-100mg. Molecular Weight 502.78. See USA prepack pricing.
Plerixafor
Plerixafor is a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-alpha (SDF-1-alpha). ntation in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma (MM). Group: Biochemicals. Grades: Highly Purified. CAS No. 110078-46-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Plerixafor (AMD3100) 8HCl
Plerixafor (AMD3100, JM 3100,Plerixafor Octahydrochloride,AMD3100 octahydrochloride,SID791 octahydrochloride) 8HCl is the hydrochloride of Plerixafor, a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively. Plerixafor can be used as an anti-HIV agent. Group: Inhibitors. Alternative Names: JM 3100 8HCl,Plerixafor Octahydrochloride,AMD3100 octahydrochloride,SID791 octahydrochloride. CAS No. 155148-31-5. Pack Sizes: 5mg. Product ID: S3013. Formula: C28H54N8.8HCl. Smiles: C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3.Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Plerixafor-d4
Labeled Plerixafor, it is a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α). Group: Biochemicals. Grades: Highly Purified. CAS No. 1246819-87-3. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Plerixafor-[d4]
Plerixafor-[d4] is the labelled analogue of Plerixafor, which is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5. 7 nM, respectively. Synonyms: Plerixafor D4; 1,1'-[(2H4)-1,4-Phenylenebis(methylene)]bis(1,4,8,11-tetraazacyclotetradecane). Grade: 95% by HPLC; 95% atom D. CAS No. 1246819-87-3. Molecular formula: C28H50D4N8. Mole weight: 506.81.
Plerixafor-d4 Hexa(trifluoroacetate)
Protected, labeled Plerixafor. Group: Biochemicals. Alternative Names: 1, 1'- [1, 4-Phenyl ene bis ( methyl ene ) ] bis [4, 8, 11-tri s (tri fluoroacetyl ) -1, 4, 8, 11-tetra azacyclotetra decane -d4. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Plerixafor Hexa(trifluoroacetate)
Protected Plerixafor. Group: Biochemicals. Alternative Names: 1, 1'- [1, 4-Phenyl ene bis ( methyl ene ) ] bis [4, 8, 11-tri s (tri fluoroacetyl ) -1, 4, 8, 11-tetra azacyclotetra decane. Grades: Highly Purified. CAS No. 4069393-93-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Plerixafor Impurity 1
Plerixafor Impurity 1. Uses: For analytical and research use. Molecular formula: C46H96Cl12N12. Mole weight: 1242.76. Catalog: APB09196.
Plerixafor Impurity 10
Plerixafor Impurity 10. Uses: For analytical and research use. Molecular formula: C24H38Cl2N4O4S2. Mole weight: 581.61. Catalog: APB09202.
Plerixafor Impurity 13
Plerixafor Impurity 13. Uses: For analytical and research use. CAS No. 16473-35-1. Molecular formula: C8H9ClO. Mole weight: 156.61. Catalog: APB16473351.
Plerixafor Impurity 14
Plerixafor Impurity 14. Uses: For analytical and research use. Molecular formula: C16H22ClF9N4O3. Mole weight: 524.81. Catalog: APB09203.
Plerixafor Impurity 15
Plerixafor Impurity 15. Uses: For analytical and research use. Molecular formula: C12H26Cl3F3N4O. Mole weight: 405.71. Catalog: APB09206.
Plerixafor Impurity 16
Plerixafor Impurity 16. Uses: For analytical and research use. Molecular formula: C14H24Cl2F6N4O2. Mole weight: 465.26. Catalog: APB09205.
Plerixafor Impurity 17
Plerixafor Impurity 17. Uses: For analytical and research use. Molecular formula: C14H24Cl2F6N4O2. Mole weight: 465.26. Catalog: APB09204.
Plerixafor Impurity 18
Plerixafor Impurity 18. Uses: For analytical and research use. Molecular formula: C14H24Cl2F6N4O2. Mole weight: 465.26. Catalog: APB09208.
Plerixafor Impurity 19
Plerixafor Impurity 19. Uses: For analytical and research use. CAS No. 406939-93-3. Molecular formula: C40H48F18N8O6. Mole weight: 1078.85. Catalog: APB406939933.
Plerixafor Impurity 2
Plerixafor Impurity 2. Uses: For analytical and research use. Molecular formula: C46H96Cl12N12. Mole weight: 1242.76. Catalog: APB09197.
Plerixafor Impurity 20
Plerixafor Impurity 20. Uses: For analytical and research use. Molecular formula: C24H29F9N4O4. Mole weight: 608.51. Catalog: APB09207.
Plerixafor Impurity 21
Plerixafor Impurity 21. Uses: For analytical and research use. Molecular formula: C24H27F9N4O4. Mole weight: 606.49. Catalog: APB09209.
Plerixafor Impurity 22
Plerixafor Impurity 22. Uses: For analytical and research use. Molecular formula: C24H28ClF9N4O3. Mole weight: 626.95. Catalog: APB09210.
Plerixafor Impurity 23
Plerixafor Impurity 23. Uses: For analytical and research use. Molecular formula: C62H76F24N12O8. Mole weight: 1573.33. Catalog: APB09215.
Plerixafor Impurity 24
Plerixafor Impurity 24. Uses: For analytical and research use. Molecular formula: C62H76F24N12O8. Mole weight: 1573.33. Catalog: APB09216.
Plerixafor Impurity 25
Plerixafor Impurity 25. Uses: For analytical and research use. Molecular formula: C62H76F24N12O8. Mole weight: 1573.33. Catalog: APB09217.
Plerixafor Impurity 26
Plerixafor Impurity 26. Uses: For analytical and research use. CAS No. 201610-16-4. Molecular formula: C18H20F12N4O4. Mole weight: 584.36. Catalog: APB201610164.
Plerixafor Impurity 27
Plerixafor Impurity 27. Uses: For analytical and research use. CAS No. 170161-28-1. Molecular formula: C20H40N4O4. Mole weight: 400.56. Catalog: APB170161281.
Plerixafor Impurity 28
Plerixafor Impurity 28. Uses: For analytical and research use. Molecular formula: C24H38Cl2N4O4S2. Mole weight: 581.61. Catalog: APB09211.
Plerixafor Impurity 3
Plerixafor Impurity 3. Uses: For analytical and research use. Molecular formula: C46H96Cl12N12. Mole weight: 1242.76. Catalog: APB09198.
Plerixafor Impurity 30
Plerixafor Impurity 30. Uses: For analytical and research use. CAS No. 267241-20-3. Molecular formula: C24H37ClN4. Mole weight: 417.04. Catalog: APB267241203.
Plerixafor Impurity 31
Plerixafor Impurity 31. Uses: For analytical and research use. Molecular formula: C28H54N8O. Mole weight: 518.79. Catalog: APB09212.
Plerixafor Impurity 32
Plerixafor Impurity 32. Uses: For analytical and research use. Molecular formula: C40H60F18N8O14. Mole weight: 1218.93. Catalog: APB09213.
Plerixafor Impurity 33
Plerixafor Impurity 33. Uses: For analytical and research use. CAS No. 74676-47-4. Molecular formula: C36H46N4O8S4. Mole weight: 791.02. Catalog: APB74676474.
Plerixafor Impurity 34
Plerixafor Impurity 34. Uses: For analytical and research use. CAS No. 71089-74-2. Molecular formula: C38H48N4O8S4. Mole weight: 817.06. Catalog: APB71089742.
Plerixafor Impurity 35
Plerixafor Impurity 35. Uses: For analytical and research use. CAS No. 104395-69-9. Molecular formula: C31H42N4O6S3. Mole weight: 662.88. Catalog: APB104395699.
Plerixafor Impurity 37
Plerixafor Impurity 37. Uses: For analytical and research use. CAS No. 6315-52-2. Molecular formula: C16H18O6S2. Mole weight: 370.43. Catalog: APB6315522.
Plerixafor Impurity 38
Plerixafor Impurity 38. Uses: For analytical and research use. CAS No. 2973-10-6. Molecular formula: C6H14O4S. Mole weight: 182.23. Catalog: APB2973106.
Plerixafor Impurity 4
Plerixafor Impurity 4. Uses: For analytical and research use. Molecular formula: C18H34Cl4N4. Mole weight: 448.30. Catalog: APB09199.
Plerixafor Impurity 40
Plerixafor Impurity 40. Uses: For analytical and research use. CAS No. 104-82-5. Molecular formula: C8H9Cl. Mole weight: 140.61. Catalog: APB104825.
Plerixafor Impurity 41
Plerixafor Impurity 41. Uses: For analytical and research use. CAS No. 626-16-4. Molecular formula: C8H8Cl2. Mole weight: 175.05. Catalog: APB626164.
Plerixafor Impurity 42
Plerixafor Impurity 42. Uses: For analytical and research use. CAS No. 612-12-4. Molecular formula: C8H8Cl2. Mole weight: 175.05. Catalog: APB612124.
Plerixafor Impurity 43
Plerixafor Impurity 43. Uses: For analytical and research use. CAS No. 73291-09-5. Molecular formula: C8H7ClO. Mole weight: 154.59. Catalog: APB73291095.
Plerixafor Impurity 44
Plerixafor Impurity 44. Uses: For analytical and research use. CAS No. 589-29-7. Molecular formula: C8H10O2. Mole weight: 138.17. Catalog: APB589297.
Plerixafor Impurity 45
Plerixafor Impurity 45. Uses: For analytical and research use. Molecular formula: C18H36Cl4N4. Mole weight: 450.31. Catalog: APB09214.
Plerixafor Impurity 46
Plerixafor Impurity 46. Uses: For analytical and research use. CAS No. 7398-44-9. Molecular formula: C8H7Cl3. Mole weight: 209.49. Catalog: APB7398449.
Plerixafor Impurity 47
Plerixafor Impurity 47. Uses: For analytical and research use. Molecular formula: C25H50N8. Mole weight: 462.73. Catalog: APB09218.
Plerixafor Impurity 48
Plerixafor Impurity 48. Uses: For analytical and research use. Molecular formula: C26H52N8. Mole weight: 476.76. Catalog: APB09228.
Plerixafor Impurity 49
Plerixafor Impurity 49. Uses: For analytical and research use. Molecular formula: C25H50N8. Mole weight: 462.73. Catalog: APB09219.
Plerixafor Impurity 5
Plerixafor Impurity 5. Uses: For analytical and research use. Molecular formula: C18H35Cl3N4O. Mole weight: 429.86. Catalog: APB09200.
Plerixafor Impurity 50
Plerixafor Impurity 50. Uses: For analytical and research use. Molecular formula: C26H52N8. Mole weight: 476.76. Catalog: APB09220.
Plerixafor Impurity 51
Plerixafor Impurity 51. Uses: For analytical and research use. Molecular formula: C29H54N8. Mole weight: 514.81. Catalog: APB09221.
Plerixafor Impurity 52
Plerixafor Impurity 52. Uses: For analytical and research use. Molecular formula: C30H54N8. Mole weight: 526.82. Catalog: APB09222.
Plerixafor Impurity 53
Plerixafor Impurity 53. Uses: For analytical and research use. Molecular formula: C28H52N8. Mole weight: 500.78. Catalog: APB09223.
Plerixafor Impurity 54
Plerixafor Impurity 54. Uses: For analytical and research use. CAS No. 5834-63-9. Molecular formula: C24H44N4O4. Mole weight: 452.64. Catalog: APB5834639.
Plerixafor Impurity 6
Plerixafor Impurity 6. Uses: For analytical and research use. Molecular formula: C18H33Cl3N4O. Mole weight: 427.84. Catalog: APB09201.
Plerixafor Impurity 8
Plerixafor Impurity 8. Uses: For analytical and research use. CAS No. 128495-30-7. Molecular formula: C17H33Cl3N4O2S. Mole weight: 463.89. Catalog: APB128495307.
Plerixafor Impurity 9
Plerixafor Impurity 9. Uses: For analytical and research use. CAS No. 123530-19-8. Molecular formula: C24H36N4O4S2. Mole weight: 508.7. Catalog: APB123530198.
Plerixafor octahydrochloride
Plerixafor octahydrochloride (AMD3100 octahydrochloride) is a selective CXCR4 antagonist with an IC50 of 44 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMD3100 octahydrochloride; JM3100 octahydrochloride; SID791 octahydrochloride. CAS No. 155148-31-5. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50912.
Pleurain-a1
Pleurain-a1 is an antimicrobial peptide found in Rana pleuraden (Yunnan pond frog, Babina pleuraden), and has antibacterial activity against gram-negative bacteria Escherichia coli, Helicobacter pylori NCTC 11637 (MIC=30 μg/ml) and gram-positive bacteria Bacillus dysenteriae (MIC=120 μg/ml), Staphylococcus aureus, and has anti-yeast activity against Candida albicans. Synonyms: Pleurain A1; Ser-Ile-Ile-Thr-Met-Thr-Lys-Glu-Ala-Lys-Leu-Pro-Gln-Leu-Trp-Lys-Gln-Ile-Ala-Cys-Arg-Leu-Tyr-Asn-Thr-Cys (Disulfide bridge: Cys20-Cys26). Grade: ≥97%. Molecular formula: C136H224N36O37S3. Mole weight: 3051.68.
Pleurain-a1-thel
Pleurain-a1-thel is an antioxidant and an antimicrobial peptide found in skin secretions, the tree frog, Theloderma kwangsiensis, Guangxi, China, Asia. It has anti-gram-negative bacteria, gram-positive bacteria and fungal activity. Synonyms: Arg-Ile-Leu-Thr-Met-Thr-Lys-Arg-Val-Lys-Met-Pro-Gln-Leu-Tyr-Lys-Gln-Ile-Val-Cys-Arg-Leu-Phe-Lys-Thr-Cys (Disulfide bridge: Cys20-Cys26). Grade: >98%. Molecular formula: C143H247N41O33S4. Mole weight: 3197.04.
Pleurain-a2
Pleurain-a2 is an antimicrobial peptide found in Rana pleuraden (Yunnan pond frog). It has activity against the gram-positive bacterium S.aureus ATCC2592 (MIC=15 μg/ml), the gram-negative bacteria E.coli ATCC25922 (MIC=60 μg/ml), B.dysenteriae (MIC=60 μg/ml), H.pylori NTCT11637 (MIC=30 μg/ml), and the fungus C.albicans ATCC2002 (MIC=30 μg/ml). It has little hemolytic activity on rabbit red blood cells. Synonyms: Pleurain A2; Ser-Ile-Ile-Thr-Met-Thr-Lys-Glu-Ala-Lys-Leu-Pro-Gln-Ser-Trp-Lys-Gln-Ile-Ala-Cys-Arg-Leu-Tyr-Asn-Thr-Cys (Disulfide bridge: Cys20-Cys26). Grade: ≥97%. Molecular formula: C133H218N36O38S3. Mole weight: 3025.60.
Pleurain-A3
Pleurain-A3 is an antimicrobial peptide found in Rana pleuraden (Yunnan pond frog). It has anti-gram-positive bacteria, gram-negative bacteria and fungal activity, and has little hemolytic activity on red blood cells. Synonyms: Pleurain A3; Ser-Ile-Ile-Thr-Met-Thr-Arg-Glu-Ala-Lys-Leu-Pro-Gln-Leu-Trp-Lys-Gln-Ile-Ala-Cys-Arg-Leu-Tyr-Asn-Thr-Cys (Disulfide bridge: Cys20-Cys26). Grade: ≥97%. Molecular formula: C136H224N38O37S3. Mole weight: 3079.70.