A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Pitavastatin-[d4] Calcium Salt, is the labelled analogue of Pitavastatin. Pitavastatin is a member of the blood cholesterol lowering medication class of statins. It is an inhibitor of HMG-CoA reductase. Synonyms: Pitavastatin D4 Calcium Salt. Grade: > 95%. Molecular formula: C50H38D8F2N2O8Ca. Mole weight: 889.03.
Pitavastatin-d5 Lactone
A labeled metabolite of Pitavastatin. Recent studies have shown that conversion between acid and lactone forms occurs in the body, drug-drug interaction should be considered on both acid and lactone forms. The inhibitory effects of statins on CYP metabolic activities and MDR1 transporting activity were investigated using human liver microsomes and MDR1-overexpressing LLC-GA5-COL150 cells. Group: Biochemicals. Alternative Names: (4R, 6S) -6- [ (1E) -2- [2- (Cyclopropyl-d5) -4- (4-fluorophenyl) -3-quinolinyl] ethenyl] tetrahydro-4-hydroxy-2H-pyran-2-one; [4R-[4α,6 β (E) ] ] -6- [2- [2- (Cyclopropyl-d5) -4- (4-fluorophenyl) -3-quinolinyl] ethenyl] tetrahydro-4-hydroxy-2H-pyran-2-one; NK 104-d5; NK 104-d5 (lactone); Nisvastatin-d5; P 872441-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Pitavastatin-d5 Sodium Salt
Labeled Pitavastatin. A HMG CoA reductase inhibitor. An antilipemic. Group: Biochemicals. Alternative Names: (3R,5S,6E)-7-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt; (+)-(3R,5S,6E)-7-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt; NK 104-d5 Sodium Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Pitavastatin ethyl ester
Pitavastatin Ethyl Ester is used as a reactant in the preparation of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: (E)-(3R,5S)-7-[2-Cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-3,5-dihydroxy-hept-6-enoic acid ethyl ester; (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Ethyl Ester; 3R,5S-DOLE; Pitavastatin Impurity 17; 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-, ethyl ester, (3R,5S,6E)-. Grade: ≥95%. CAS No. 167073-19-0. Molecular formula: C27H28FNO4. Mole weight: 449.51.
Pitavastatin Impurity 10
Pitavastatin Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-4-hydroxytetrahydro-2H-pyran-2-one. CAS No. 141750-63-2. Molecular formula: C25H22FNO3. Mole weight: 403.45. Catalog: APB141750632.
Pitavastatin Impurity 38
Pitavastatin Impurity 38. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 2-((4R,6S)-6-((Z)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 154170-27-1. Molecular formula: C32H36FNO4. Mole weight: 517.63. Catalog: APB154170271.
Pitavastatin Impurity 59
Pitavastatin Impurity 59. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 2-((4S,6R)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 1044518-75-3. Molecular formula: C13H22O5. Mole weight: 258.31. Catalog: APB1044518753.
Pitavastatin Impurity 62
Pitavastatin Impurity 62. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 2-((4R,6S)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 154026-95-6. Molecular formula: C15H26O6. Mole weight: 302.36. Catalog: APB154026956.
Pitavastatin Impurity 63
Pitavastatin Impurity 63. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 124655-09-0. Molecular formula: C13H24O5. Mole weight: 260.33. Catalog: APB124655090.
Pitavastatin Impurity 65
Pitavastatin Impurity 65. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-((bromotriphenylphosphoranyl)methyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline. CAS No. 154057-58-6. Molecular formula: C37H30BrFNP. Mole weight: 618.52. Catalog: APB154057586.
Pitavastatin Impurity 68
Pitavastatin Impurity 68. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline. CAS No. 154057-56-4. Molecular formula: C19H15BrFN. Mole weight: 356.23. Catalog: APB154057564.
Pitavastatin Impurity 74
Pitavastatin Impurity 74. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 167934-30-7. Molecular formula: C29H30FNO4. Mole weight: 475.55. Catalog: APB167934307.
Pitavastatin Impurity 9
Pitavastatin Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 167073-19-0. Molecular formula: C27H28FNO4. Mole weight: 449.52. Catalog: APB167073190.
Pitavastatin lactone
Pitavastatin lactone is a major metabolite of Pitavastatin in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 141750-63-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-125643.
Pitavastatin Lactone-[d4]
One of the isotopic labelled metabolites of Pitavastatin, which has a potent cholesterol-lowering action. Synonyms: Pitavastatin Lactone D4. Grade: >98%. Molecular formula: C25H18D4FNO3. Mole weight: 407.48.
PITCOIN4
PITCOIN4 is a highly selective Class II Alpha PI3K-C2? inhibitor. PITCOIN4 shows nanomolar inhibition of PI3K-C2? and >100-fold selectivity in a general kinase panel[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156406.
Pitofenone hydrochloride
Pitofenone hydrochloride, a spasmolytic compound, inhibits the acetylcholinesterase ( AChE ) activity from bovine erythrocytes and from electric eel with K i s of 36 and 45 μM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1248-42-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110389.
Pitofenone Hydrochloride
Diclofenac and its combination with Pitofenone and Fenpiverinium. Group: Biochemicals. Alternative Names: 2-[4-[2- (1-Piperidinyl) ethoxy]benzoyl]benzoic Acid. Grades: Highly Purified. CAS No. 1248-42-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Pitolisant
Pitolisant is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor ( K i =0.16 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tiprolisant. CAS No. 362665-56-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12199.
Pitolisant hydrochloride
Pitolisant hydrochloride is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor ( K i =0.16 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ciproxidine; BF 2649. CAS No. 903576-44-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12199B.
pitrilysin
From the periplasmic space of Escherichia coli. Inhibited by EDTA and 1,10-phenanthroline; not thiol-dependent. Type example of peptidase family M16. Group: Enzymes. Synonyms: Escherichia coli protease III; protease Pi; proteinase Pi; PTR; Escherichia coli metalloproteinase Pi. Enzyme Commission Number: EC 3.4.24.55. CAS No. 81611-78-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4337; pitrilysin; EC 3.4.24.55; 81611-78-1; Escherichia coli protease III; protease Pi; proteinase Pi; PTR; Escherichia coli metalloproteinase Pi. Cat No: EXWM-4337.
Pitstop 2
Pitstop 2 is a clathrin inhibitor which inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. Pitstop 2 has the potential for anti-cancer research[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1419320-73-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115604.
Pittosapogenin is a triterpenoid compound. CAS No. 15399-43-6. Molecular formula: C30H50O6. Mole weight: 506.71.
Pituitary (Anterior), Equine
Collected from certified collection facilities in the Unites States. Special requirements can be accomodated, such as sex, age, breed and weight. Group: Biologicals. Grades: Tissue. Pack Sizes: 1Ea. US Biological Life Sciences.
Worldwide
Pituitary (Posterior), Equine
Collected from certified collection facilities in the Unites States. Special requirements can be accomodated, such as sex, age, breed and weight. Group: Biologicals. Grades: Tissue. Pack Sizes: 1Ea. US Biological Life Sciences.
Worldwide
Pituitary, Rabbit
Pituitary, Rabbit. Group: Biologicals. Grades: Tissue. Pack Sizes: 100Ea. US Biological Life Sciences.
Worldwide
Pituitary, Whole, Equine
Collected from certified collection facilities in the Unites States. Special requirements can be accomodated, such as sex, age, breed and weight. Group: Biologicals. Grades: Tissue. Pack Sizes: 1Ea. US Biological Life Sciences.
Worldwide
Pituitary, Whole, Porcine
Young pigs average weight 200lb, 6-8 months old, mixed breed and gended; tissue collected on wet ice and frozen at -20°C within 2-6 hours of sacrifice. Average tissue weight: 0.2g. Group: Biologicals. Grades: Tissue. Pack Sizes: 25Ea. US Biological Life Sciences.
Pivagabine (CXB 722) is a hydrophobic 4-aminobutyric acid derivative with neuromodulatory activity. Pivagabine penetrates the blood-brain barrier in rats. Pivagabine antagonizes the effects of foot shock on both GABAA receptor function and corticotropin-releasing factor (CRF) concentrations in rat brain [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CXB-722. CAS No. 69542-93-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-108295.
Pivalaldehyde (Tri methyl acetaldehyde)
Pivalaldehyde (Tri methyl acetaldehyde) . Group: Biochemicals. Alternative Names: Trimethylacetaldehyde. Grades: Highly Purified. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
Pivalamide
White powder, 98%. Synonym: 2,2-Dimethylpropionamide. CAS No. 754-10-9. Pack Sizes: Typically in stock: 25g, 100g. Mole weight: 101.15. MP/BP: M.P. 154-155. Order No: FR-0367.
Frinton Laboratories
Pivalanilide
Crystalline powder, 98%. Synonym: N-Phenylpivalamide. CAS No. 6625-74-7. Pack Sizes: Typically in stock: 5g, 25g. Mole weight: 177.25. MP/BP: M.P. 130-133. Order No: FR-0364.
Frinton Laboratories
Pivaldehyde
Pivaldehyde. Group: Biochemicals. Alternative Names: Trimethylacetaldehyde; 2,2-Dimethylpropanal; 2,2-Dimethylpropanone. Grades: Highly Purified. CAS No. 630-19-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C5H10O. US Biological Life Sciences.
Worldwide
Pivaldehyde
Trimethylacetaldehyde (CAS# 630-19-3) is a compound useful in organic synthesis. Alternative Names: Trimethylacetaldehyde. PIVALALDEHYDE. Pivaldehyde. 2,2-Dimethylpropanal. CAS No. 630-19-3. Product ID: CHE630193. Molecular formula: C5H10O. Mole weight: 86.13. EINECS: 211-134-6. SMILES: CC(C)(C)C=O. Appearance: Liquid. Category: Other Chemicals.
Pivalexin
Pivalexin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PIVCEPHALEXIN;PIVALEXIN;(pivaloyloxy)methyl [6R-[6alpha,7beta(R*)]]-7-(aminophenylacetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;(6R)-7α-[[(R)-Aminophenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carb. Product Category: Heterocyclic Organic Compound. CAS No. 63836-75-9. Molecular formula: C22H28ClN3O6S. Mole weight: 497.99. Product ID: ACM63836759. Alfa Chemistry ISO 9001:2015 Certified.
Pivalic Acid
Pivalic Acid is a metabolite of oral cephem ( β-lactam) antibiotics such as S-1108, containing pivaloyl moieties. Group: Biochemicals. Alternative Names: 2,2-Dimethylpropanoic Acid; 2,2,2-Trimethylacetic Acid; 2,2-Dimethylpropanoic Acid; 2,2-Dimethylpropionic Acid; NSC 65449; Neopentanoic Acid; Neovaleric Acid; Trimethylacetic Acid; Tri methyl methanecarboxylic Acid; Versatic 5 Acid; tert-Pentanoic Acid; α,α-Dimethylpropionic Acid. Grades: Highly Purified. CAS No. 75-98-9. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
Pivalic acid hydrazide
Pivalic acid hydrazide. Group: Biochemicals. Grades: Highly Purified. CAS No. 42826-42-6. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Pivaloin
Pivaloin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pivaloin, NSC1054, MolPort-000-489-139, MolPort-000-982-994, HMS1649P03, CID219593, NSC407548, 4-Hydroxy-2,2,5,5-tetramethyl-3-hexanone, 3-Hexanone, 4-hydroxy-2,2,5,5-tetramethyl-, F0400-0014, 815-66-7. Product Category: Heterocyclic Organic Compound. CAS No. 815-66-7. Molecular formula: C10H20O2. Mole weight: 172.26. Purity: 0.96. IUPACName: 4-hydroxy-2,2,5,5-tetramethylhexan-3-one. Canonical SMILES: CC(C)(C)C(C(=O)C(C)(C)C)O. Density: 0.912g/cm³. Product ID: ACM815667. Alfa Chemistry ISO 9001:2015 Certified. Categories: Pivalonitrile.
Pivalolactone in chlororom - 1.6% w/v
Pivalolactone in chlororom - 1.6% w/v. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 3.125ml. US Biological Life Sciences.
Worldwide
Pivalonitrile
Pivalonitrile. Group: Biochemicals. Alternative Names: Trimethylacetonitrile. Grades: Highly Purified. CAS No. 630-18-2. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C5H9N. US Biological Life Sciences.
Worldwide
Pivaloylacetonitrile
Pivaloylacetonitrile. Group: Biochemicals. Grades: Highly Purified. CAS No. 59997-51-2. Pack Sizes: 1kg, 2kg, 5kg, 10kg, 25kg. US Biological Life Sciences.
Worldwide
Pivampicillin Hydrochloride
Semi-synthetic antibiotic related to Penicillin. Antibacterial. Group: Biochemicals. Alternative Names: (2S, 5R, 6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3, 3-dimethyl-7-oxo-4-thia-1-azabicyclo[3. 2. 0]heptane-2-carboxylic Acid (2,2-Dimethyl-1-oxopropoxy)methyl Ester Hydrochloride Alphacilina; Alphacillin; Ampicillin Pivaloxyoxymethyl Ester Hydrochloride; Berocillin; Centurina; Diancina; Inacilin; Maxifen; Pivaloyloxymethyl D- (-) - α -Aminophenyl acetamidopenicillanate Hydrochloride; Pivatil; Pondocil; Pondocillin; Pondocillina; Sanguicillin. Grades: Purified. CAS No. 26309-95-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Pivarose
Pivarose (Phenyl Ethyl Pivalate). CAS No. 67662-96-8. Kosher: Y. VIGON Item # 500875. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers.
America & Internationally
Pivekimab
Pivekimab is a human IgG1 monoclonal antibody that targets interleukin-3 (IL-3) and CD123. Pivekimab is used to synthesize pivekimab sunirine, a CD123-directed antibody-active molecule conjugate ( ADC ). Pivekimab is used in the study of blastic plasmacytoid dendritic cell neoplasm (BPDCN) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2234335-84-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99234.
Pividium bromide impurity 15
Pividium bromide impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1235355-01-7. Molecular formula: C26H39Br2NO4. Mole weight: 589.41. Catalog: APB1235355017.
Pivmecillinam
Pivmecillinam. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PIVMECILLINAM;PIVAMDINOCILLIN;AMDINOCILLIN PIVOXIL;PIVMECILLINAM IMPURITY CMETHYLENE 2,2-DIMETHYLPROPANOATE (2RS,4S)-2-[[[(HEXAHYDO-1H-AZEPIN-1-YL)METHYLENE]AMINO]METHYL]-5,5-DIMETHYLTHIAZOLIDIN-4-CARBOXYLATE EPP(CRM STANDARD);(2S,5β)-6α-[[(Hexahydro-1H-. Product Category: Heterocyclic Organic Compound. Appearance: crystals. CAS No. 32886-97-8. Molecular formula: C21H33N3O5S. Mole weight: 439.574. Product ID: ACM32886978. Alfa Chemistry ISO 9001:2015 Certified.
Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FL-1039 hydrochloride. CAS No. 32887-03-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0810A.
Pivmecillinam Hydrochloride
Pivmecillinam Hydrochloride. Group: Biochemicals. Alternative Names: (2S, 5R, 6R)-6-[[(Hexahydro-1H-azepin-1-yl)methylene]amino]-3, 3-dimethyl-7-oxo-4-thia-1-azabicyclo[3. 2. 0]heptane-2-carboxylic Acid (2,2-Dimethyl-1-oxopropoxy)methyl Ester Hydrochloride. Grades: Highly Purified. CAS No. 32887-03-9. Pack Sizes: 50mg. Molecular Formula: C21H34ClN3O5S, Molecular Weight: 476.03. US Biological Life Sciences.
Worldwide
Pivmecillinam (hydrochloride) (Standard)
Pivmecillinam (hydrochloride) (Standard) is the analytical standard of Pivmecillinam (hydrochloride). This product is intended for research and analytical applications. Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic. Uses: Scientific research. Group: Signaling pathways. CAS No. 32887-03-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0810AR.
Pixantrone
Pixantrone (BBR 2778) dimaleate is a topoisomerase II inhibitor and DNA intercalator, with anti-tumor activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BBR 2778. CAS No. 144675-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13727A.
Pizotifen
Pizotifen. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pizotyline;Piperidine, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methyl-. Product Category: Thiophenes. Appearance: White to Off-White Solid. CAS No. 15574-96-6. Molecular formula: C19H21NS. Mole weight: 295.44. Purity: 0.98. Product ID: ACM15574966. Alfa Chemistry ISO 9001:2015 Certified.
Pizotifen (Pizotyline) is a potent 5-HT 2 receptor antagonist, with a high affinity for 5-HT 1C binding site. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pizotyline; BC-105. CAS No. 15574-96-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0115.
Pizotifen malate
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H21NS.C4H6O5. CAS No. 5189-11-7. Prepack ID 12889487-1g. Molecular Weight 429.53. See USA prepack pricing.
Pizotifen malate
Pizotifen malate (Pizotyline malate) is a potent 5-HT 2 receptor antagonist, with a high affinity for 5-HT 1C binding site. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pizotyline malate; BC-105 malate. CAS No. 5189-11-7. Pack Sizes: 100 mg. Product ID: HY-B0115A.
Pizotyline
Serotonin antagonist structurally related to Cyproheptadine. Antimigraine; appetite stimulant. Group: Biochemicals. Alternative Names: 4-(9, 10-Dihydro-4H-benzo[4, 5]cyclohepta[1, 2-b]thien-4-ylidene)-1-methylpiperidine. Grades: Highly Purified. CAS No. 15574-96-6. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
PJ34
PJ34 is a potent specific inhibitor of PARPl/2 with IC50 of 110 nM and 86 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 344458-19-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13688A.
PJ 34 Hydrochloride
A poly adenosine diphosphate-ribose polymerase inhibitor, attenuates chromate-induced nephrotoxicity. Group: Biochemicals. Alternative Names: N- (5, 6-Dihydro-6-oxo-2-phenanthridinyl) -2- (dimethylamino) acetamide. Grades: Highly Purified. CAS No. 344458-15-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
PJ-34 Hydrochloride
A potent, water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor (EC50 = 20nM). Inhibits peroxynitrite-induced cell necrosis and displays significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Suppresses cell growth in liver cancer cells. Group: Biochemicals. Alternative Names: N-(6-Oxo-5,6-dihydro-phenanthridin-2-yl)-N,N-dimethylacetamide Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Potent, water soluble poly(ADP-ribose) polymerase (PARP) inhibitor. Inhibits peroxynitrite-induced cell necrosis. Shows significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Shows protective effects in models of stroke. Suppresses cell growth in liver cancer cells. Group: Biochemicals. Alternative Names: N-(6-Oxo-5,6-dihydro-phenanthridin-2-yl)-N,N-dimethylacetamide. HCl. Grades: Highly Purified. CAS No. 344458-15-7. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences.
Worldwide
pJAK2(1001-1013)
pJAK2(1001-1013) is a SOCS1/3 antagonist. pJAK2(1001-1013) plays a positive role in antiviral immune response by inhibiting the negative regulatory effect of SOCS proteins and enhancing the JAK/STAT signaling pathway[1]. Uses: Scientific research. Group: Peptides. CAS No. 1259928-08-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P10373.
PK11007
PK11007 is a mild thiol alkylator with anticancer activity. PK11007 stabilizes p53 via selective alkylation of two surface-exposed cysteines without compromising its DNA binding activity. PK11007 induces mutant p53 cancer cell death by increasing reactive oxygen species (ROS) levels[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 874146-69-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128784.
An isoquinoline carboxamide that acts as a potent ligand for peripheral bezodiazepine receptor (Kd = 20nM). Exhibits anti-inflammatory properties. Binds to monocytes and following lesioning its binding up-regulated in brain macrophages and activated microglia. Shown to enhance the susceptibility of cells to apoptosis induction by DNA damaging agents and can reverse the suppression of apoptosis by Bcl-2. Serves as a ligand of the outer membrane translocator protein and reduces mitochondrial transmembrane potential within 30 minutes of exposure (100uM).CAS Number:85532-75-8. Group: Biochemicals. Grades: Highly Purified. CAS No. 85532-75-8. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O. US Biological Life Sciences.
Worldwide
PK 11195
Cell-permeable. A Selective peripheral benzodiazepine antagonist. Enhances apoptosis and induces mitochondria cytochrome c release. Inhibits insulin secretion induced by glucose. Also displays anticancer activity. Group: Biochemicals. Alternative Names: 1- (2-Chloro phenyl ) -N- methyl -N- (1- methyl propyl ) -3-isoquinolinecarboxamid e . Grades: Highly Purified. CAS No. 85532-75-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PK 11195
PK 11195 (RP 52028) is a ligand of translocator protein (TSPO) , which targets Leishmania chemotherapy, with IC 50 s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis , L. major and L. braziliensis , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RP 52028. CAS No. 85532-75-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19567.