A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
PKC (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (IC50 = 0.18 μM). Synonyms: Gly-Arg-Pro-Arg-Thr-Ser-Ser-Phe-Ala-Glu-Gly. Grade: >97%. CAS No. 113731-96-7. Molecular formula: C93H159N35O24. Mole weight: 2151.48.
PKC Activator VII, CGK062 (Protein Kinase C Activator VII)
A cell permeable coumarin-containing compound that is shown to activate PKCalpha activity and induce cellular PKCalpha membrane translocation (Effective conc. 12.5 to 50uM) as well as PKCalpha-mediated signaling events. Effectively affects the viability of CRT-dependent cancer cells (IC50 = 1.62 to 18.6uM; 48h) in vitro and suppresses PC3-derived tumor expansion in mice (50 & 100mg/kg/day; i.p) in vivo, while exhibiting little cytotoxicity toward WI38 normal fibroblasts. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C??H??O?, Primary Target IC50: 12.2uM. US Biological Life Sciences.
Worldwide
PKCβII Peptide Inhibitor I trifluoroacetate salt
PKCβII Peptide Inhibitor I trifluoroacetate salt. Uses: For analytical and research use. CAS No. 862502-26-9 (free base). Mole weight: 1299.47 (free base basis). Catalog: ALP862502269.
PKC β pseudosubstrate
PKC β pseudosubstrate, a selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM), consists of amino acids 19-31 of PKC pseudosubstrate domain linked by a disulphide bridge to a cell permeabilisation Antennapedia domain vector peptide. Synonyms: PKC beta pseudosubstrate; Protein kinase C beta pseudosubstrate; H-Cys(1)-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-OH.H-Cys(1)-Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val-OH; L-cysteinyl-L-arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-arginyl-L-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine (1->1')-disulfide compound with L-cysteinyl-L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysyl-glycyl-L-alanyl-L-leucyl-L-arginyl-L-glutaminyl-L-lysyl-L-asparagyl-L-valine. Grade: >98%. CAS No. 172308-76-8. Molecular formula: C177H294N62O38S3. Mole weight: 3994.84.
PKC-theta inhibitor 1
PKC-theta inhibitor 1 is an orally active and selective ATP-competitive inhibitor of Protein Kinase Cθ (PKCθ), with a Ki value of 6 nM. PKC-theta inhibitor 1 inhibits T-cell-mediated inflammatory responses by suppressing the release of proinflammatory cytokines (IL-2 IC50 = 0.21 μM in anti-CD3/CD28-stimulated PBMCs; IL-17 IC50 = 1 μM in CD3/CD28-stimulated Th17 cells) PKC-theta inhibitor 1 significantly reduces symptoms in mice with ongoing experimental autoimmune encephalomyelitis (EAE). PKC-theta inhibitor 1 can be used for the study of T-cell-mediated inflammatory diseases such as multiple sclerosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1160501-81-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-126328.
PKC-theta inhibitor 2
PKC-theta inhibitor 2 is a potent and selective PKC-θ inhibitor with an IC50 value of 18 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 736048-65-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112681.
PKCζ-IN-1
PKCζ-IN-1 is a compound that inhibits PKCζ and CDK2, showing an IC50 value of 5.18 nM for PKCζ and 1.04 μM for CDK2, with significant selectivity of 200-fold. PKCζ-IN-1 can reduce the activity of CDK2 while inhibiting PKCζ. Uses: Scientific research. Category: Signaling pathways. CAS No. 1132609-87-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-120497.
PKC ζ pseudosubstrate acetate
PKC ζ pseudosubstrate acetate, a synthetic peptide, is an inhibitor of protein kinase C (PKC) ζ that is attached to cell permeabilization Antennapedia domain vector peptide. It consists of amino acids 113-129 PKC ζ pseudosubstrate domains connected by a disulfide bridge to the cell permeabilization Antennapedia domain vector peptide. Synonyms: Protein kinase C zeta pseudosubstrate acetate; L-cysteinyl-L-seryl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginyl-glycyl-L-alanyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-lysyl-L-leucyl-L-tyrosyl-L-arginyl-L-alanyl-L-asparagine (1->1')-disulfide compound with L-cysteinyl-L-arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-arginyl-L-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine; H-Cys-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-Tyr-Arg-Ala-Asn-OH.H-Cys-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-OH (Disulfide bridge: Cys1-Cys1'). Grade: ≥95%. Molecular formula: C210H340N74O46S3. Mole weight: 4733.68.
PKG inhibitor peptide TFA
PKG inhibitor peptide TFA is an ATP-competitive inhibitor of cGMP-dependent protein kinase (PKG) with a Ki of 86 μM. It is an analog of a substrate peptide corresponding to a phosphorylation site of histone H2B, and inhibits phosphorylation of intact histones by PKA. Synonyms: H-Arg-Lys-Arg-Ala-Arg-Lys-Glu-OH.TFA; L-arginyl-L-lysyl-L-arginyl-L-alanyl-L-arginyl-L-lysyl-L-glutamic acid trifluoroacetic acid; cGMP Dependent Kinase Inhibitor Peptide TFA. Grade: ≥95%. Molecular formula: C40H75F3N18O12. Mole weight: 1057.13.
PKG Substrate
PKG Substrate is a selective substrate for cGMP-dependent protein kinase (PKG). Synonyms: Arg-Lys-Arg-Ser-Arg-Ala-Glu; L-arginyl-L-lysyl-L-arginyl-L-seryl-L-arginyl-L-alanyl-L-glutamic acid; N5-(Diaminomethylidene)-L-ornithyl-L-lysyl-N5-(diaminomethylidene)-L-ornithyl-L-seryl-N5-(diaminomethylidene)-L-ornithyl-L-alanyl-L-glutamic acid; (S)-2-((6S,9S,12S,15S,18S,21S)-1,6-diamino-9-(4-aminobutyl)-12,18-bis(3-guanidinopropyl)-15-(hydroxymethyl)-1-imino-21-methyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosanamido)pentanedioic acid. Grade: ≥95%. CAS No. 81187-14-6. Molecular formula: C35H67N17O11. Mole weight: 902.01.
PKG Substrate acetate
PKG Substrate acetate is a selective substrate for cGMP-dependent protein kinase (PKG). Synonyms: H-Arg-Lys-Arg-Ser-Arg-Ala-Glu-OH.CH3CO2H; L-arginyl-L-lysyl-L-arginyl-L-seryl-L-arginyl-L-alanyl-L-glutamic acid acetic acid. Grade: ≥95%. Molecular formula: C37H71N17O13. Mole weight: 962.08.
PKH 26
PKH 26 is a red fluorescent dye, PKH 26 can stably bind to the lipid region of cell membrane and emit red fluorescence (Ex/Em=551/567 nm), which is mainly used for in vitro cell labeling, in vitro cell proliferation studies and in vivo and in vitro cell tracing studies[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 154214-55-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D1451.
PKH 26 (solution)
PKH 26 (solution) is a red fluorescent dye, PKH 26 can stably bind to the lipid region of cell membrane and emit red fluorescence (Ex/Em=551/567 nm) , which is mainly used for in vitro cell labeling, in vitro cell proliferation studies and in vivo and in vitro cell tracing studies[1].Solvent and concentration: DMSO: 5 mM. Uses: Scientific research. Category: Signaling pathways. CAS No. 154214-55-8. Pack Sizes: 20 μL; 50 μL. Product ID: HY-DY1011.
PKH 67
PKH67 is a fluorescent cell binding dye with green fluorescence. PKH67 can stain the cell membrane and the Ex/Em is 490/502 nm. PKH67 is often used in combination with the non-specific red fluorescent dye PKH26 (Ex/Em=551/567 nm) to label cells, detect cell proliferation in vitro, and trace cells in vitro and in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 257277-27-3. Pack Sizes: 100 μL; 1 mL. Product ID: HY-D1421.
PKI 14-22 amide,myristoylated
PKI 14-22 amide, myristoylated is a selective, cAMP-dependent, competitive PKA inhibitor with Ki=~36 nM. The myristoylation modification of PKI 14-22 amide, myristoylated makes it more permeable to cell membranes and blood-brain barriers than the precursor molecule. PKI 14-22 amide, myristoylated can block the phosphorylation of cAMP-dependent downstream targets (such as CREB). PKI 14-22 amide, myristoylated can prevent the development of morphine analgesic tolerance in mice, and also inhibits protein translation and negative-strand RNA synthesis of Zika virus. PKI 14-22 amide, myristoylated can be used in research fields such as opioid tolerance mechanisms and antiviral drugs[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 201422-03-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1291.
PKI 14-22 amide, myristoylated
PKI 14-22 amide, myristoylated is a cell-permeable version of protein kinase inhibitor PKI (14-22) amide. N-terminus is myristoylated to increase cell membrane permeability. The non-myristoylated version of this peptide is a highly specific inhibitor of cAMP-dependent protein kinase (PKA) with Ki=36 nM. This product is a useful tool for studying PKA in cellular systems. Synonyms: Protein kinase inhibitor-(14-22)-amide, myristoylated. Grade: >98%. CAS No. 201422-03-9. Molecular formula: C53H100N20O12. Mole weight: 1209.5.
PKI 14-22 amide, myristoylated
PKI 14-22 amide, myristoylated. Group: Biochemicals. Grades: Purified. CAS No. 201422-03-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
PKI 166 hydrochloride
PKI 166 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PKI-179
PKI-179 is a potent and orally active dual PI3K/mTOR inhibitor, with IC50s of 8 nM, 24 nM, 74 nM, 77 nM, and 0.42 nM for PI3K-α, PI3K-β, PI3K-γ, PI3K-δ and mTOR, respectively. PKI-179 also exhibits activity over E545K and H1047R, with IC50s of 14 nM and 11 nM, respectively. PKI-179 shows anti-tumor activity in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1197160-28-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11080.
PKI (5-24)
PKI (5-24) is a competitive, non-reversible peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki = 2.3 nM). Its sequence is derived from the heat-stable skeletal muscle inhibitor protein of PKA. The PKA Inhibitor peptide binds to the catalytic subunit of PKA and displaces the regulatory subunit, and mimics protein substrate by binding to the catalytic site via the Arg-cluster basic residues. Synonyms: L-threonyl-L-threonyl-L-tyrosyl-L-alanyl-L-a-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-serylglycyl-L-arginyl-L-threonylglycyl-larginyl-L-aspartic acid; PKI (5-24); Protein Kinase A Inhibitor (5-24). CAS No. 99534-03-9. Molecular formula: C94H148N32O31. Mole weight: 2222.4.
PKI(5-24)
PKI(5-24) is a potent, competitive, and synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase), with a Ki of 2.3 nM. PKI(5-24) corresponds to residues 5-24 in the naturally occurring heat-stable protein kinase inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 99534-03-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0222.
PKI (5-24) acetate
PKI (5-24) acetate is a competitive, non-reversible peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki = 2.3 nM). Synonyms: H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-OH.CH3CO2H; L-Threonyl-L-threonyl-L-tyrosyl-L-alanyl-L-α-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-serylglycyl-L-arginyl-L-threonylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-alanyl-L-isoleucyl-L-histidyl-L-aspartic acid acetate salt; PKI(5-24) acetate salt. Grade: ≥95%. Molecular formula: C96H152N32O33. Mole weight: 2282.43.
PKL-IN-1
PKL-IN-1 is a potent inhibitor of pyruvate kinase (PKL) with an IC50 of 0.07 μM. PKL-IN-1 can be used in the study of non-alcoholic fatty liver disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3078059-66-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161337.
PKM2-IN-1 (compound 3k) is a pyruvate kinase M2 (PKM2) inhibitor with an IC50 of 2.95 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 94164-88-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103617.
PKM2-IN-1 (Compound 3k)
PKM2 inhibitor(Compound 3K, PKM2-IN-1) displays PKM2 inhibitory activity with the IC50 value of 2.95 μM. The IC50 value for PKM1 is 4-5-fold higher than that for PKM2. Group: Inhibitors. Alternative Names: PKM2-IN-1. CAS No. 94164-88-2. Pack Sizes: 5mg. Product ID: S8616. Formula: C18H19NO2S2. Smiles: CC1=C(C(=O)C2=CC=CC=C2C1=O)CSC(=S)N3CCCCC3. Storage Conditions: 2 years -80 in solvent.
United States; Europe
PKM2-IN-6
PKM2-IN-6 (compound 7d) is a potent and orally active PKM2 inhibitor with an IC50 value of 23 nM. PKM2-IN-6 induces apoptosis and cell cycle arrest at G2 phase. PKM2-IN-6 reduces the level of PKM1 and PKM2 at the mRNA level. PKM2-IN-6 shows anticancer activity and has the potential for the research of triple-negative breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 771467-00-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157913.
PKN1/2-IN-1
PKN1/2-IN-1 is a potent cell permeabilizer and selective PKN1/2 inhibitor with IC50 values of 16 nM and 210 nM for PKN1 and PKN2, respectively, and Ki values of 8 nM and 108 nM, respectively. PKN1/2-IN-1 exhibits strong intracellular PKN2 binding capacity in NanoBRET assays (IC50 = 2.1 μM). PKN1/2-IN-1 can be used to study physiological processes such as tumor cell migration[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 942425-34-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145899.
PKRA83
PKRA83 (PKRA7) is a potent prokineticin (PK2) antagonist, which can compete for the binding of PK2 to its receptors PKR1 and PKR2. PKRA83 potently inhibits PK2 receptors, with IC50 values of 5.0 nM and 8.2 nM for PKR1 and PKR2, respectively. PKRA83 has anticancer, anti-arthritis and anti-angiogenic activities. [1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PKRA7. CAS No. 1233926-87-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147056.
PKR-IN-C16
PKR-IN-C16 (Compound C16) is a specific double-stranded RNA-dependent protein kinase (PKR) inhibitor. PKR-IN-C16 shows promising neuroprotective properties and can rescue acute brain lesions[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 608512-97-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13977A.
PKR-IN-C51
PKR-IN-C51(compound 51) is an ATP-competitive double-stranded RNA-activated protein kinase (PKR) inhibitor with an IC50 of 9 μM. PKR-IN-C51 inhibits intracellular PKR activation in a dose-dependent manner in primary mouse macrophages[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1314594-23-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118131.
PKSI-527
PKSI-527 is a new, highly selective plasma kallikrein inhibitor. PKSI-527 can suppress collagen-induced arthritis (CIA) by modifying the kallikrein-kinin system[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 128837-71-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123133.
PK-THPP
PK-THPP. Group: Biochemicals. Grades: Purified. CAS No. 1332454-07-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PK-THPP
PK-THPP is a potent and brain-penetrant TWIK-related acid-sensitive K+ ion channel (K2P9.1 or TASK-3) blocker with IC50s of 35 nM and 300 nM for TASK-3 and TASK-1, respectively. PK-THPP shows no or less activity against other K+ channels. PK-THPP is an effective breathing stimulant and can be used for the study of breathing disorders[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1332454-07-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-110184.
PKUMDL-LC-101-D04
PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a glutathione peroxidase 4 (GPX4) allosteric activator (pEC50=4.7). PKUMDL-LC-101-D04 can inhibit ferroptosis and inflammation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GPX4-Activator-1d4. CAS No. 2143896-83-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-115627.
PL 017
PL 017. Group: Biochemicals. Grades: Purified. CAS No. 83397-56-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
PL-101
PL-101 is an antibacterial peptide isolated from Styela plicata. Grade: >96%.
PLA2G12A from Human, Recombinant
Human PLA2G12A (GenBank Accession No. NM_030821), amino acids 23-189 (end) with C-terminal His-tag, MW=22 kDa, expressed in a mammalian cell expression system. Human pla2g12a (genbank accession no. nm_030821), amino acids 23-189 (end) with c-terminal his-tag, mw=22 kda, expressed in a mammalian cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: PLA2G12A; phospholipase A2; GXII; Phospholipase A2 G12; ROSSY; PLA2G12. Purity: > 80% (SDS-PAGE). PLA2. Mole weight: mol wt 22 kDa. Storage: -20°C. Form: aqueous solution; Fomulated in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 200 mM Imidazole, and 20% Glycerol. Source: Mammalian cells. Species: Human. PLA2G12A; phospholipase A2; GXII; Phospholipase A2 G12; ROSSY; PLA2G12. Cat No: NATE-0589.
PLA2G12B from Human, Recombinant
Human PLA2G12B (GenBank Accession No. NM_032562), amino acids 20-295 (end) with C-terminal His tag, MW=21.1 kDa, expressed in a mammalian cell expression system. Human pla2g12b (genbank accession no. nm_032562), amino acids 20-295 (end) with c-terminal his tag, mw=21.1 kda, expressed in a mammalian cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: PLA2G12B; phospholipase A2; FKSG71; GXIIB; Phospholipase A2 G12. Purity: > 60% (SDS-PAGE). PLA2. Mole weight: mol wt 21.1 kDa. Storage: -70°C. Form: aqueous solution; Fomulated in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 200 mM Imidazole, and 20% Glycerol. Source: Mammalian cells. Species: Human. PLA2G12B; phospholipase A2; FKSG71; GXIIB; Phospholipase A2 G12. Cat No: NATE-0590.
PLA 3D printing filament
PLA 3D printing filament. CAS No. 9051-89-2.
PLA-b-PPEEA
Polylactic acid (PLA) is a kind of non-toxic,non irritating synthetic polymer material with excellent biodegradability,compatibility and absorbability.It can be used as drug transport material and tissue engineering scaffold material. Synonyms: polylactic acid-b-PPEEA. Product ID: MSMN-062. Category: Raw Materials.
Plactin A
Plactin A is a cyclic pentapeptide physiologically active substance produced by the fungus F165. It can promote the dissolution of fibrinolytic protein. Molecular formula: C32H52N8O6. Mole weight: 644.80.
Plactin B
Plactin B is a cyclic pentapeptide physiologically active substance produced by the fungus F165. It can promote the dissolution of fibrinolytic protein. Synonyms: Plastin B. Molecular formula: C32H52N8O6. Mole weight: 644.80.
Plactin C
Plactin C is a cyclic pentapeptide physiologically active substance produced by the fungus F165. It can promote the dissolution of fibrinolytic protein. Synonyms: cyclo(-D-Val-L-Leu-D-alloIle-L-Phe-D-Arg-). Molecular formula: C32H52N8O5. Mole weight: 628.80.
Plactin D
Plactin D is a cyclic pentapeptide physiologically active substance produced by the fungus F165. It can promote the dissolution of fibrinolytic protein. Synonyms: Plastin D; cyclo(-D-Val-L-Leu-D-Leu-L-Phe-D-Arg-). Molecular formula: C32H52N8O5. Mole weight: 628.80.
p-Lacto-N-hexaose
p-Lacto-N-hexaose. CAS No. 64331-48-2. Purity: Min. 90%. Product ID: ALC-FP-64331482. Molecular formula: C40H68N2O31. Mole weight: 1072.96. Alfa Chemistry - ISO 9001:32057 Certified.
Placulumab
Placulumab (ART621) is an anti-TNF α monoclonal antibody. Placulumab has anti-inflammatory activity and has potential applications in inflammatory diseases such as arthritis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ART621; CEP-37247; PN0621. CAS No. 945781-29-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99775.
Pladienolide B
Pladienolide B is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome. Pladienolide B exerts antitumor activities mediated through the inhibition of pre-mRNA splicing. Pladienolide B induces apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 445493-23-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 μg; 500 μg; 1 mg; 5 mg. Product ID: HY-16399.
Pladienolide B
a potent pre-mRNA splicing inhibitor. Pladienolide B has shown strong inhibitory effect against activity and growth of various cell lines via targeting SF3b. Synonyms: (3R,6R,7S,8E,10S,11S,12E,14E,16S,18R,19R,20R,21S)-7-acetoxy-3,6,21-trihydroxy-6,10,12,16,20-pentamethyl-18,19-epoxytricosa-8,12,14-triene-11-olide; [(2~{S},3~{S},4~{E},6~{S},7~{R},10~{R})-3,7-dimethyl-2-[(2~{E},4~{E},6~{S})-6-methyl-7-[(2~{R},3~{R})-3-[(2~{R},3~{S})-3-oxidanylpentan-2-yl]oxiran-2-yl]hepta-2,4-dien-2-yl]-7,10-bis(oxidanyl)-12-oxidanylidene-1-oxacyclododec-4-en-6-yl] ethanoate; Pla-B, 5. Grade: ≥95% by HPLC. CAS No. 445493-23-2. Molecular formula: C30H48O8. Mole weight: 536.71.
Pladienolide D
Pladienolide D is an antitumor macrolide produced by Streptomyces platensis. CAS No. 445487-91-2. Molecular formula: C30H48O9. Mole weight: 552.7.
Plain ExoLiposome
The product is composed of lipids that are consistent with exosomes, which mimic the natural properties of exosomes with the easy modification properties of liposomes. Group: Exoliposome.
Plamotamab (XmAb-13676) is a human bispecific antibody (bsAb) that binds CD3 and CD20. Plamotamab recruits cytotoxic T cells to kill CD20+ expressing tumor cells. Plamotamab induces a mild hematologic reaction (MR), and results in tumor regression in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XmAb-13676. CAS No. 2138442-31-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99776.
Planaic acid
It is produced by the strain of Lecidea plana and L.lithophila. Synonyms: Plana acid; Planasaeure; 2-Methoxy-4-(2,4-dimethoxy-6-pentylbenzoyloxy)-6-pentylbenzoic acid. CAS No. 5366-7-4. Molecular formula: C27H36O7. Mole weight: 472.57.
Plantain Leaf Powder & P.E. 10:1
Plantain Leaf Powder & P.E. 10:1.
CA, FL & NJ
Plantainoside D
Plantainoside D, a phenylethanoid glycosides, is a IKK-β inhibitor with diverse biological activities. Plantainoside D shows inhibitory activity of angiotensin-converting enzyme (ACE) with an IC50 of 2.17 mM. Plantainoside D significantly reduces the release of glutamate from nerve terminals in the cerebral cortex of rats by inhibiting the voltage-dependent calcium channel (VDCCs) and protein kinase C (PKC) signaling cascade. Plantainoside D significantly alleviates cell apoptosis by inhibiting the generation of ROS and the activation of NF-κB. Plantainoside D significantly improves acute lung injury (ALI) induced by sepsis by regulating the Sirt3/NLRP3 signaling pathway. Plantainoside D can be used for the study of neuroprotection, antioxidant, anti-inflammation, antihypertension[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 147331-98-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N5063.
Plantainoside D
Plantainoside D. Group: Biochemicals. CAS No. 147331-98-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Plantamajoside
Plantamajoside. Group: Biochemicals. Alternative Names: Plantamoside; Purpureaside A. Grades: Plant Grade. CAS No. 104777-68-6. Pack Sizes: 20mg. Molecular Formula: C29H36O16, Molecular Weight: 640.587. US Biological Life Sciences.
Worldwide
Plantamajoside
Plantamajoside is an orally active phenylpropanoid glycoside. Plantamajoside can be isolated from Plantago asiatica L.(Plantaginaceae). Plantamajoside inactivates NF-κB, PI3K/akt, induces Apoptosis, and improves Autophagy. Plantamajoside regulates MAPK, integrin-linked kinase/c-Src. Plantamajoside inhibits multiple cancers, improves lung and kidney damage. Plantamajoside has neuroprotective and anti-inflammatory effects[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19]. Uses: Scientific research. Category: Signaling pathways. CAS No. 104777-68-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0031.
Plantaricin-149
Plantaricin-149 is an antimicrobial peptide found in Lactobacillus plantarum NRIC 149, and has antibacterial activity. Grade: >98%. CAS No. 155421-98-0.
Plantaricin 163
Plantaricin 163 is an antibacterial peptide isolated from Lactobacillus plantarum 163. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Val-Phe-His-Ala-Tyr-Ser-Ala-Arg-Gly-Asn-Tyr-Tyr-Gly-Asn-Cys-Pro-Ala-Asn-Trp-Pro-Ser-Cys-Arg-Asn-Asn-Tyr-Lys-Ser-Ala-Gly-Gly-Lys.
Plantaricin 423
Plantaricin 423 is an antimicrobial peptide found in Lactobacillus plantarum 423, and has antibacterial activity. Grade: >98%. CAS No. 183681-68-7.
Plantaricin A
Plantaricin A is an antimicrobial peptide found in Lactobacillus plantarum C11, WCFS1, V90. It has anti-gram-positive bacteria, gram-negative bacteria and Cancer cells activity. Synonyms: H-Ala-Tyr-Ser-Leu-Gln-Met-Gly-Ala-Thr-Ala-Ile-Lys-Gln-Val-Lys-Lys-Leu-Phe-Lys-Lys-Trp-Gly-Trp-OH; L-alanyl-L-tyrosyl-L-seryl-L-leucyl-L-glutaminyl-L-methionyl-glycyl-L-alanyl-L-threonyl-L-alanyl-L-isoleucyl-L-lysyl-L-glutaminyl-L-valyl-L-lysyl-L-lysyl-L-leucyl-L-phenylalanyl-L-lysyl-L-lysyl-L-tryptophyl-glycyl-L-tryptophan. Grade: ≥96%. CAS No. 131463-18-8. Molecular formula: C128H200N32O29S. Mole weight: 2683.22.
Plantaricin A
Plantaricin A is an antimicrobial peptide that can be derived from Lactobacillus plantarum. Plantaricin A has a synergistic effect with Ciprofloxacin. Plantaricin A shows anti-microbial activity. Plantaricin A increases the membrane potential of S. aureus and the level of intracellular ROS. Plantaricin A inhibits the function of the efflux pump by binding it and altering the structure of MepA, NorA, and LmrS. Plantaricin A significantly relieves inflammation, and promotes wound healing. Plantaricin A permeabilizes cancerous rat pituitary cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PlnA. CAS No. 131463-18-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5589.
Plantaricin C19
Plantaricin C19 is an antimicrobial peptide and an anti-Listeria bacteriocin found in Lactobacillus plantarum C19, and has antibacterial activity. Grade: >98%. CAS No. 153858-63-0.
Plantaricin EF
Plantaricin EF is an antimicrobial peptide found in Lactobacillus plantarum C11, and has antibacterial activity. Synonyms: Phe-Asn-Arg-Gly-Gly-Tyr-Asn-Phe-Gly-Lys-Ser-Val-Arg-His-Val-Val-Asp-Ala-Ile-Gly-Ser-Val-Ala-Gly-Ile-Leu-Lys-Ser-Ile-Arg. Grade: ≥96%. CAS No. 209623-63-2. Molecular formula: C144H233N45O39. Mole weight: 3218.72.
Plantaricin JK
Plantaricin JK is an antimicrobial peptide found in Lactobacillus plantarum C1, and has antimicrobial activity. Synonyms: Gly-Ala-Trp-Lys-Asn-Phe-Trp-Ser-Ser-Leu-Arg-Lys-Gly-Phe-Tyr-Asp-Gly-Glu-Ala-Gly-Arg-Ala-Ile-Arg-Arg. Grade: ≥95%. CAS No. 209623-64-3. Molecular formula: C133H198N42O34. Mole weight: 2929.31.
Plantaricin NC8
Plantaricin NC8 is an antimicrobial peptide found in Lactobacillus plantarum NC8, and has antimicrobial activity. Synonyms: Leu-Thr-Thr-Lys-Leu-Trp-Ser-Ser-Trp-Gly-Tyr-Tyr-Leu-Gly-Lys-Lys-Ala-Arg-Trp-Asn-Leu-Lys-His-Pro-Tyr-Val-Gln-Phe. Grade: ≥95%. CAS No. 515130-54-8. Molecular formula: C169H244N42O38. Mole weight: 3472.07.
Plantaricin S
Plantaricin S is an antimicrobial peptide found in Lactobacillus plantarum LPCO10, and has antibacterial activity. Synonyms: Asn-Lys-Leu-Ala-Tyr-Asn-Met-Gly-His-Tyr-Ala-Gly-Lys-Ala-Thr-Ile-Phe-Gly-Leu-Ala-Ala-Trp-Ala-Leu-Leu-Ala. Grade: ≥97%. CAS No. 148937-56-8.