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| Product | Description | |
|---|---|---|
| Quizartinib dihydrochloride | Quizartinib dihydrochloride (AC220 dihydrochloride) is the dihydrochloride salt form of Quizartinib (HY-13001). Quizartinib dihydrochloride is an orally active, highly selective and potent second-generation type II FLT3 tyrosine kinase inhibitor, with a K d of 1.6 nM. Quizartinib dihydrochloride inhibits wild-type FLT3 and FLT3-ITD autophosphorylation in MV4-11 cells with IC 50 s of 4.2 and 1.1 nM, respectively. Quizartinib dihydrochloride can be linked to the VHL ligand via an optimized linker to form a PROTAC FLT3 degrader. Quizartinib dihydrochloride induces apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AC220 dihydrochloride. CAS No. 1132827-21-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14217. |  |
| quorum-quenching N-acyl-homoserine lactonase | Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate the expression of virulence genes in a processknown as quorum-sensing. Each bacterial cell has a basal level of AHL and, once thepopulation density reaches a critical level, it triggers AHL-signalling which, in turn,initiates the expression of particular virulence genes.Plants or animals capable of degrading AHLs would have a therapeutic advantage in avoiding bacterial infection as they could prevent AHL-signalling and the expression of virulence genes in quorum-sensing bacteria. N-(3-Oxohexanoyl)-L-homoserine lactone, N-(3-oxododecanoyl)-L-homoserine lactone. 7-43-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3510; quorum-quenching N-acyl-homoserine lactonase; EC 3.1.1.81; 389867-43-0; acyl homoserine degrading enzyme; acyl-homoserine lactone acylase; AHL lactonase; AHL-degrading enzyme; AHL-inactivating enzyme; AHLase; AhlD; AhlK; AiiA; AiiA lactonase; AiiA-like protein; AiiB; AiiC; AttM; delactonase; lactonase-like enzyme; N-acyl homoserine lactonase; N-acyl homoserine lactone hydrolase; N-acyl-homoserine lactone lactonase; N-acyl-L-homoserine lactone hydrolase; quorum-quenching lactonase; quorum-quenching N-acyl homoserine lactone h. |  |
| QUPD | QUPD. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N4,N4'-Bis (4- (6- ( (3-ethy loxetan-3-y l)methoxy)hexy loxy)pheny l)-N4,N4'-bis (4-methoxypheny l)bipheny l-4,4'-diamine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 864130-79-0. Molecular formula: C62H76N2O8. Mole weight: 945.28 g/mol. Product ID: ACM864130790. Alfa Chemistry ISO 9001:2015 Certified. Categories: Quadratic equation. |  |
| Q-VD-OPh | Q-VD-OPh is an irreversible pan-caspase inhibitor with potent antiapoptotic properties; inhibits caspase 7 with an IC50 of 48 nM and 25-400 nM for other caspases including caspase 1, 3, 8, 9, 10, and 12. Q-VD-OPh can inhibits HIV infection. Q-VD-OPh is able to cross the blood-brain barrier. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QVD-OPH; Quinoline-Val-Asp-Difluorophenoxymethylketone. CAS No. 1135695-98-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12305. | |
| Q-VD-OPH | QVD-OPH, also known as Quinoline-Val-Asp-Difluorophenoxymethylketone, is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 (IC50 = 25nm), caspase-1 (IC50 = 50nM), caspase-8 (IC50 = 100nM) and caspase-9 (IC50 = 430nM). It can be used in Alzheimer's studies relating to caspase-6, the cysteinyl protease involved in neurodegenerative conditions. As well it is an intermediate in the formation of Palinavir, a potent HIV protease inhibitor. Synonyms: Q-VD-OPH; Quinoline-Val-Asp-Difluorophenoxymethylketone; quinoline-val-asp(OMe)-CH2-OPH. Grade: >98%. CAS No. 1135695-98-5. Molecular formula: C26H25F2N3O6. Mole weight: 513.8. |  |
| Q-VD-OPh (Anhydrous) | Cell permeable, irreversible and non-toxic non-FMK pan-caspase inhibitor with improved potency, stability and toxicity over Z-VAD-FMK. Does not cross-react with cathepsins nor calpains. Non-toxic due to the 2,6- difluorophenoxy methyl (OPh) group. The peptide is not O-methylated to reduce hydrophobicity and to facilitate use in aqueous media. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction. Decreases proteasome activity. Used in apoptosis and inflammasome studies. CAS Number:1135695-98-5 (anhydrous). Group: Biochemicals. Alternative Names: Q-Val-Asp-OPh; pan-Caspase Inhibitor; N-(2-Quinolyl)-L-valyl-L-aspartyl-(2,6-difluorophenoxy) methylketone, (3S) -5- (2, 6-Difluorophenoxy) -3-[[ (2S) -3-methyl-1-oxo-2-[ (2-quinolinylcarbonyl) amino]butyl]amino]-4-oxo-pentanoic Acid. Grades: Highly Purified. CAS No. 1135695-98-5. Pack Sizes: 1mg, 3x1mg, 5mg. Molecular Formula: C??H??F?N?O?. US Biological Life Sciences. |  Worldwide |
| Q-VD-OPh hydrate | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Q-VE-OPh (Negative Control) | Cell permeable, non-toxic negative control for the caspase inhibitor Q-VD-OPh. Stable in aqueous environment. Several folds less inhibitory activity than Q-VD-OPh. Perfect for both in vitro and in vivo studies. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C27H27F2N3O6. US Biological Life Sciences. | Worldwide |
| QX 222 | QX 222. Group: Biochemicals. Grades: Purified. CAS No. 5369-00-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| QX 314 bromide | QX 314 bromide. Group: Biochemicals. Grades: Highly Purified. CAS No. 24003-58-5. Pack Sizes: 100mg. Molecular Formula: C16H27N2OBr, Molecular Weight: 343.31. US Biological Life Sciences. | Worldwide |
| QX-314 bromide | QX-314 bromide is a membrane-impermeable permanently charged sodium channel blocker [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24003-58-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-101350. | |
| QX 314 chloride | QX 314 chloride. Group: Biochemicals. Grades: Purified. CAS No. 5369-3-9. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| QX-314 chloride | QX-314 chloride is a membrane-impermeable permanently charged sodium channel blocker [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5369-3-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-108505. | |
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