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| Product | Description | |
|---|---|---|
| Quizartinib dihydrochloride | Quizartinib (AC220) dihydrochloride is an orally active, potent and selective FLT3 inhibitor. Quizartinib dihydrochloride inhibits kinase activity of mutant-FLT3, -PDGFRA and -KIT isoforms and inhibits autophosphorylation. Quizartinib dihydrochloride inhibits cellular proliferation, induces apoptosis in cancer cells. Quizartinib dihydrochloride can be used for the research of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AC220 dihydrochloride. CAS No. 1132827-21-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14217. |  |
| quorum-quenching N-acyl-homoserine lactonase | Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate the expression of virulence genes in a processknown as quorum-sensing. Each bacterial cell has a basal level of AHL and, once thepopulation density reaches a critical level, it triggers AHL-signalling which, in turn,initiates the expression of particular virulence genes.Plants or animals capable of degrading AHLs would have a therapeutic advantage in avoiding bacterial infection as they could prevent AHL-signalling and the expression of virulence genes in quorum-sensing bacteria. N-(3-Oxohexanoyl)-L-homoserine lactone, N-(3-oxododecanoyl)-L-homoserine lactone. 7-43-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3510; quorum-quenching N-acyl-homoserine lactonase; EC 3.1.1.81; 389867-43-0; acyl homoserine degrading enzyme; acyl-homoserine lactone acylase; AHL lactonase; AHL-degrading enzyme; AHL-inactivating enzyme; AHLase; AhlD; AhlK; AiiA; AiiA lactonase; AiiA-like protein; AiiB; AiiC; AttM; delactonase; lactonase-like enzyme; N-acyl homoserine lactonase; N-acyl homoserine lactone hydrolase; N-acyl-homoserine lactone lactonase; N-acyl-L-homoserine lactone hydrolase; quorum-quenching lactonase; quorum-quenching N-acyl homoserine lactone h. |  |
| Quorum Sensing-IN-2 | Quorum Sensing-IN-2 (compound 23e) is a quorum sensing inhibitor that reduces bacterial pathogenicity without affecting growth, exhibits minimal hemolytic activity, effectively inhibits bacterial infections, and shows a synergistic effect when combined with Ciprofloxacin in a P. aeruginosa PAO1-infected bacteremia model. Category: Active pharmaceutical ingredients. CAS No. 2925926-80-1. Product ID: API2925926801. Molecular formula: C19H13F2NO3. Mole weight: 341.31. |  |
| Q-VD-Oph | Q-VD-Oph (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a potent pan-caspase inhibitor with IC50 ranged from 25 to 400 nM for caspases 1,3,8, and 9. Q-VD-OPh can inhibits HIV infection. Group: Inhibitors. Alternative Names: Quinoline-Val-Asp-Difluorophenoxymethylketone. CAS No. 1135695-98-5. Pack Sizes: 1mg. Product ID: S7311. Formula: C26H25F2N3O6. Smiles: CC(C)C(C(=O)NC(CC(=O)O)C(=O)COC1=C(C=CC=C1F)F)NC(=O)C2=NC3=CC=CC=C3C=C2. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Q-VD-OPh | Q-VD-OPh is an irreversible pan-caspase inhibitor with potent antiapoptotic properties; inhibits caspase 7 with an IC50 of 48 nM and 25-400 nM for other caspases including caspase 1, 3, 8, 9, 10, and 12. Q-VD-OPh can inhibits HIV infection. Q-VD-OPh is able to cross the blood-brain barrier. Uses: Scientific research. Category: Signaling pathways. Alternative Names: QVD-OPH; Quinoline-Val-Asp-Difluorophenoxymethylketone. CAS No. 1135695-98-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12305. | |
| Q-VD-OPH | QVD-OPH, also known as Quinoline-Val-Asp-Difluorophenoxymethylketone, is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 (IC50 = 25nm), caspase-1 (IC50 = 50nM), caspase-8 (IC50 = 100nM) and caspase-9 (IC50 = 430nM). It can be used in Alzheimer's studies relating to caspase-6, the cysteinyl protease involved in neurodegenerative conditions. As well it is an intermediate in the formation of Palinavir, a potent HIV protease inhibitor. Alternative Names: Q-VD-OPH; Quinoline-Val-Asp-Difluorophenoxymethylketone; quinoline-val-asp(OMe)-CH2-OPH. Grades: >98%. CAS No. 1135695-98-5. Molecular formula: C26H25F2N3O6. Mole weight: 513.8. |  |
| QWF Peptide | QWF Peptide (Compound 4a) is a substance P antagonist with an IC50 of 0.09 μM. QWF Peptide antagonizes the SP-induced contraction of isolated guinea pig trachea strips with an IC50 of 4.7 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 126088-82-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-135108. | |
| QX 222 | QX 222. Group: Biochemicals. Grades: Purified. CAS No. 5369-00-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| QX 314 bromide | QX 314 bromide. Group: Biochemicals. Grades: Highly Purified. CAS No. 24003-58-5. Pack Sizes: 100mg. Molecular Formula: C16H27N2OBr, Molecular Weight: 343.31. US Biological Life Sciences. | Worldwide |
| QX-314 bromide | QX-314 bromide is a membrane-impermeable permanently charged sodium channel blocker[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 24003-58-5. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-101350. | |
| QX 314 chloride | QX 314 chloride. Group: Biochemicals. Grades: Purified. CAS No. 5369-3-9. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| QX-314 chloride | QX-314 chloride is a membrane-impermeable permanently charged sodium channel blocker[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5369-3-9. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-108505. | |
| QX77 | QX77 is a chaperone-mediated autophagy (CMA) activator and upregulates LAMP2A expression in vitro. QX77 induces Rab11 upregulation, rescues Rab11 down-regulation and trafficking deficiency in cystinotic cells[1]. QX77 can impede self-renewal and promote differentiation of ES cells[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1798331-92-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112483. | |
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