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Rp-6-Phe-cAMPS is a potent biomedical compound, showcasing its applications in targeting and regulating the intricate network of cyclic adenosine monophosphate (cAMP) pathways. This groundbreaking product exhibits immense potential in ameliorating dysregulated cAMP signaling, aiding in research on afflictions spanning cancer, metabolic disorders and cardiovascular diseases. CAS No. 169335-91-5. Molecular formula: C16H15N5O5PS · Na. Mole weight: 443.4.
RP 70676
RP 70676 is a potent and orally bioavailable inhibitor of ACAT. Group: Inhibitors. Alternative Names: RP 70676; RP70676; RP-70676. CAS No. 136609-26-2. Molecular formula: C25H28N4S. Mole weight: 416.59. Appearance: Solid powder. Purity: >98%. IUPACName: 1-(5-((4,5-diphenyl-1H-imidazol-2-yl)thio)pentyl)-3,5-dimethyl-1H-pyrazole. Canonical SMILES: CC1=CC (C)=NN1CCCCCSC2=NC (C3=CC=CC=C3)=C (C4=CC=CC=C4)N2. Catalog: ACM136609262.
Rp 71955
Rp 71955 is an antibacterial peptide isolated from Streptomyces sp. It has activity against viruses. Synonyms: aborycin; Cys-Leu-Gly-Ile-Gly-Ser-Cys-Asn-Asp-Phe-Ala-Gly-Cys-Gly-Tyr-Ala-Val-Val-Cys-Phe-Trp. Molecular formula: C97H131N23O26S4. Mole weight: 2163.5.
RP-71955
RP-71955 is a tricyclic 21 amino acid peptide produced by Streptomyces sp. SP9400. It is active against HIV-1. Synonyms: RP 71955; RP71955. CAS No. 152835-17-1. Molecular formula: C97H131N23O26S4. Mole weight: 2163.5.
Rp-8-AEA-cAMPS
Rp-8-AEA-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and other markers. Synonyms: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer. Grades: ≥ 98% by HPLC. CAS No. 221904-78-5. Molecular formula: C12H18N7O5PS. Mole weight: 403.4.
Rp-8-AEA-cAMPS-Agarose
Rp-8-AEA-cAMPS-Agarose is the metabolically stable protein kinase A inhibitor Rp-cAMPS immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinase A (presumably as its holoenzyme), phosphodiesterases and others. Synonyms: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, immobilized on agarose gel.
Rp-8-AET-cGMPS
Rp-8-AET-cGMPS is a ligand in affinity chromatography and can be modified with fluorophores or other markers. Synonyms: 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer. Grades: ≥ 98% by HPLC. CAS No. 221904-88-7. Molecular formula: C12H17N6O6PS2. Mole weight: 436.4.
Rp-8-AET-cGMPS-Agarose
Rp-8-AET-cGMPS-Agarose is the metabolically stable protein kinase G inhibitor Rp-cGMPS immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer; immobilized on agarose gel.
Rp-8-AHA-cAMPS
Rp-8-AHA-cAMPS is a PDE-resistant analogue of Rp-cAMPS, the PKA inhibitor, which is used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. Synonyms: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer. Grades: ≥ 98% by HPLC. CAS No. 214272-02-3. Molecular formula: C16H26N7O5PS. Mole weight: 459.5.
Rp-8-AHA-cAMPS-Agarose
Rp-8-AHA-cAMPS-Agarose is the metabolically stable protein kinase A inhibitor Rp-cAMPS immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinase A (presumably as its holoenzyme), phosphodiesterases and others. Synonyms: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer; immobilized on agarose gel.
Rp-8-Br-2'-O-MB-cAMPS
Rp-8-Br-2'-O-MB-cAMPS is a precursor of Rp-8-Br-cAMPS, the protein kinase A inhibitor. Rp-8-Br-cAMPS and butyrate are released after the metabolism of Rp-8-Br-2'-O-MB-cAMPS by esterases. Synonyms: 8- Bromo- 2'- O- monobutyryladenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 788807-32-9. Molecular formula: C14H16BrN5O6PS · Na. Mole weight: 516.2.
Rp-8-Br-cAMPS
Rp-8-Br-cAMPS is an analogue of the cAMP with a preference for type I of protein kinase A. Compared to Rp-cAMPS, it has more lipophilic and membrane-permeant properties. Rp-8-Br-cAMPS effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Synonyms: 8- Bromoadenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 129735-00-8. Molecular formula: C10H10BrN5O5PS · Na. Mole weight: 446.2.
Rp-8-Br-cGMPS
Rp-8-Br-cGMPS is an inhibitor of protein kinase G I α and I ß. It effects against mammalian cyclic nucleotide- dependent phosphodiesterases. Compared to cGMP or Rp-cGMPS, it has more lipophilic and membrane-permeant properties. Synonyms: 8- Bromoguanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 150418-07-8. Molecular formula: C10H10BrN5O6PS · Na. Mole weight: 462.2.
Rp-8-bromo-Cyclic AMPS sodium salt
Rp-8-bromo-Cyclic AMPS is a cell-permeable cAMP analog and an antagonist of cAMP-dependent protein kinases (PKAs). Synonyms: 8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer; Rp-8-Br-cAMPS; Rp-8-bromo-cAMPS. Grades: ≥98%. CAS No. 925456-59-3. Molecular formula: C10H10BrN5O5PS·Na. Mole weight: 446.1.
Rp-8-bromo-Cyclic GMPS sodium salt
Rp-8-bromo-Cyclic GMPS is a cell-permeable analog of cGMP and an inhibitor of cGMP-dependent protein kinase (cGK). Synonyms: 8-bromo-guanosinecyclic3',5'-[(R)-(hydrogenphosphorothioate)], monosodium salt; Rp-8-Br-cGMPS; Rp-8-bromo-cGMPS. Grades: ≥99%. CAS No. 208445-06-1. Molecular formula: C10H10BrN5O6PS·Na. Mole weight: 462.1.
Rp-8-bromo-PET-Cyclic GMPS sodium salt
Rp-8-bromo-PET-Cyclic GMPS is an analog of cyclic GMP (cGMP) and an inhibitor of cGMP-dependent protein kinases (cGKs). Synonyms: Rp-8-Br-PET-cGMPS; Rp-8-bromo-PET-cGMPS. Grades: ≥99%. CAS No. 185246-32-6. Molecular formula: C18H14BrN5O6PS·Na. Mole weight: 562.27.
Rp-8-Br-PET-cGMPS
Rp-8-Br-PET-cGMPS is a selective inhibitor of cGMP-dependent protein kinase I a and I β and of retinal cGMP-gated ion channels. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to Rp-8-pCPT-cGMPS, it is much more lipophilic and membrane-permeant. Synonyms: 8- Bromo- β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 172806-20-1. Molecular formula: C18H14BrN5O6PS · Na. Mole weight: 562.3.
Rp-8-Br-PET-cGMPS
Rp-8-Br-PET-cGMPS. Group: Biochemicals. Grades: Purified. CAS No. 185246-32-6. Pack Sizes: 560ug. US Biological Life Sciences.
Worldwide
Rp-8-Cl-cAMPS
Rp-8-Cl-cAMPS is a selective and competitive inhibitor of protein kinase A (cAMP antagonist) preferring type I of protein kinase A. It inhibits mammalian cyclic nucleotide-dependent phosphodiesterases. Synonyms: 8- Chloroadenosine- 3', 5'- monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 142754-27-6. Molecular formula: C10H10ClN5O5PS · Na. Mole weight: 401.7.
Rp-8-CPT-cAMPS
Rp-8-CPT-cAMPS is an analog of Rp-cAMPS and a competitive inhibitor of protein kinase A type I and II (cAMP antagonist). It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to Rp-8-Br-cAMPS, it is more lipophilic and membrane-permeant. Synonyms: 8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 129735-01-9. Molecular formula: C16H14ClN5O5PS2 · Na. Mole weight: 509.8.
Rp-8-CPT-Cyclic AMP sodium salt
Rp-8-CPT-cAMP is a combination of lipophilic and hydrolizable cAMP analogs, 8-CPT-cyclic AMP and Rp-cyclic AMPS. It also acts as a site-selective inhibitor of protein kinase A (PKA) type I and II. Synonyms: Rp-8-CPT-cAMP. Grades: ≥98%. CAS No. 221905-35-7. Molecular formula: C16H14ClN5O5PS2·Na. Mole weight: 509.8.
Rp-8-OH-cAMPS
Rp-8-OH-cAMPS is a polar analogue of Rp-cAMPS, the protein kinase A inhibitor, used for the study of extracellular cAMP receptors. It inhibits mammalian cyclic nucleotide-dependent phosphodiesterases. Synonyms: 8- Hydroxyadenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 475084-30-1. Molecular formula: C10H11N5O6PS · Na. Mole weight: 383.3.
Rp-8-pCPT-cGMPS
Rp-8-pCPT-cGMPS is a selective inhibitor of protein kinase G I a, I ß and especially of type II, which stimulates retinal cGMP channels and discriminates between kinase and channel effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to Rp-cGMPS or Rp-8-Br-cGMPS, it exhibits more lipophilic and membrane-permeant properties. Synonyms: 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 153660-04-9. Molecular formula: C16H14ClN5O6PS2 · Na. Mole weight: 525.9.
Rp-8-pCPT-cGMPS sodium
Rp-8-pCPT-cGMPS sodium, a stable, cell-permeable cGMP analog, is a PKG inhibitor (Ki= 0.45, 0.5 and 0.7 μM for PKGIβ, PKGIα and PKGII respectively). Synonyms: 8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3',5'-[hydrogen [P(R)]-phosphorothioate] sodium; Rp-8-pCPT-cGMPS. Grades: ≥99% by HPLC. CAS No. 208445-07-2. Molecular formula: C16H14ClN5NaO6PS2. Mole weight: 525.86.
Rp-8-pCPT-PET-cGMPS
Rp-8-pCPT-PET-cGMPS is an inhibitor of protein kinase G and probably of retinal cGMP-gated ion channels. It has a resistant against mammalian cyclic nucleotide-dependent phosphodiesterases. Synonyms: 8- (4- Chlorophenylthio)-β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 1262749-62-1. Molecular formula: C24H18ClN5O6PS2 · Na. Mole weight: 626.
Rp-8-PIP-cAMPS
Rp-8-PIP-cAMPS is a selective analogue of Rp-cAMPS, the protein kinase A inhibitor, preferring site B of cAK type II. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to Rp-cAMPS, it has more lipophilic and membrane-permeant properties. Synonyms: 8- Piperidinoadenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 156816-36-3. Molecular formula: C15H20N6O5PS · Na. Mole weight: 450.4.
RPA 202248
RPA 202248. Group: Biochemicals. Alternative Names: α-(Cyclopropylcarbonyl)-2-(methylsulfonyl)- β -oxo-4- (trifluoromethyl) benzenepropanenitrile. Grades: Highly Purified. CAS No. 143701-75-1. Pack Sizes: 5mg. Molecular Formula: C15H12F3NO4S, Molecular Weight: 359.32. US Biological Life Sciences.
Worldwide
R-Palmitoyl-(2-methyl) ethanolamide
R-Palmitoyl-(2-methyl) ethanolamide is a metabolite of palmitoyl ethanolamide (PEA), an anti-inflammatory endogenous cannabinoid. R-Palmitoyl-(2-methyl) ethanolamide shows weak CB receptor affinity. Synonyms: RP-2ME; (R)-palmitic monoisopropanolamide; N-[(2R)-2-hydroxypropyl]hexadecanamide. Grades: ≥98%. CAS No. 179951-56-5. Molecular formula: C19H39NO2. Mole weight: 313.5.
Rp-cAMPS, sodium salt
Rp-cAMPS is a competitive inhibitor of protein kinase A type I and II (cAMP antagonist), which has a higher affinity for type II of protein kinase A. It exhibits a resistant effect of mammalian cyclic nucleotide-dependent phosphodiesterases. Uses: Protein kinase inhibitors. Synonyms: Adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 73208-40-9. Molecular formula: C10H11N5O5PS · Na. Mole weight: 367.3.
Rp-cAMPS, triethyl ammonium salt
Rp-cAMPS is a competitive inhibitor of protein kinase A type I and II, the cAMP antagonist, which has high selectivity of type II of protein kinase A. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Uses: Protein kinase inhibitors. Synonyms: Adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, triethyl ammonium salt. Grades: ≥ 98% by HPLC. CAS No. 151837-09-1. Molecular formula: C10H11N5O5PS · C6H16N. Mole weight: 446.5.
Rp-cCMPS
Rp-cCMPS is a PDE-resistant cCMP, the potential second messenger, which inhibits cCMP-binding proteins. Synonyms: Cytidine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 87063-79-4. Molecular formula: C9H11N3O6PS · Na. Mole weight: 343.2.
Rp-c-diAMPS
Rp-c-diAMPS is an analogue of c-diAMP, the bacterial second messenger. Synonyms: Cyclic diadenosine monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H24N10O11P2S (free acid). Mole weight: 674.5 (free acid).
Rp-c-diGMPS
Rp-c-diGMPS is an analogue of c-diGMP, the bacterial second messenger, which can be used to study ligand-receptor interactions. Synonyms: Cyclic diguanosine monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1259875-32-5. Molecular formula: C20H24N10O13P2S (free acid). Mole weight: 706.5 (free acid).
Rp-cGMPS
Rp-cGMPS is an inhibitor of protein kinase G Iα with an antagonistic effect of mammalian cyclic nucleotide-dependent phosphodiesterases. Both membrane permeability and kinase specificity of Rp-cGMPS are low. Synonyms: Guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 86562-09-6. Molecular formula: C10H11N5O6PS · Na. Mole weight: 383.3.
Rp-dUTP-α-S
Rp-dUTP-α-S is a paramount instrument assuming a pivotal role in substrate allocation for enzymatic facilitation of DNA replication and repair mechanisms. Its utility extends to the elucidation of potential pharmaceutical targets by means of DNA sequencing and labeling techniques. Synonyms: 2'- Deoxyuridine- 5'- O- (1- thiotriphosphate), Rp- isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 876068-86-9. Molecular formula: C9H15N2O13P3S (free acid). Mole weight: 484.2 (free acid).
RPE65-IN-1
RPE65-IN-1(Compound 16e) is a potent RPE65 inhibitor, which can be used in retinopathy-related research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1141779-07-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-149325.
R-PE (R-Phycoerythrin)
R-Phycoerythrin is a phycobiliproteins could be isolated from Heterosiphonia japonica. R-Phycoerythrin is a potent fluorescent probe contains four chromophore-carrying subunits that exhibits extremely bright red-orange fluorescence. (λex=496 nm, λem=578 nm) [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 11016-17-4. Pack Sizes: 1 mg (22 mg/mL * 45 μL in buffer (buffer containing 60% (NH4)2SO4)); 5 mg (22 mg/mL * 227 μL in buffer (buffer containing 60% (NH4)2SO4)); 10 mg (22 mg/mL * 455 μL in buffer (buffer containing 60% (NH4)2SO4)). Product ID: HY-D0988.
Rp-GDP-α-S
Rp-GDP-α-S is a GDP binding proteins regulator with high stability, which is used for characterization of GDP-responsive receptors and determination of their stereospecificity. Synonyms: Guanosine- 5'- O- (1- thiodiphosphate), Rp- isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 71481-44-2. Molecular formula: C10H15N5O10P2S (free acid). Mole weight: 459.3 (free acid).
The enzyme, characterized from the cyanobacterium Synechococcus sp. WH8102, catalyses the covalent attachment of the phycobilin chromophore phycoerythrobilin to cysteine 84 of the α subunit of the phycobiliprotein R-phycocyanin and its isomerization to phycourobilin. Group: Enzymes. Synonyms: rpcG (gene name). Enzyme Commission Number: EC 4.4.1.33. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5336; R-phycocyanin α-cysteine-84 phycourobilin lyase/isomerase; EC 4.4.1.33; rpcG (gene name). Cat No: EXWM-5336.
R-PHYCOCYANIN FROM PORPHYRIDIUM*CRUENTUM
Heterocyclic Organic Compound. CAS No. 11021-52-6. Purity: 0.96. Catalog: ACM11021526.
RPI-1
RPI-1 is a specific, orally available 2-indolinone Ret tyrosine kinase inhibitor. RPI-1 inhibits proliferation, Ret tyrosine phosphorylation, Ret protein expression, and the activation of PLCgamma, ERKs and AKT in human medullary thyroid carcinoma TT cells. Antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 269730-03-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101246.
RPI-1
RPI-1 is a cell-permeable, ATP-dependent RET kinase inhibitor. Oral treatment with RPI-1 caused growth arrest or regression in 81% treated tumors. It can also be used in biological study of proteomics study of medullary thyroid carcinomas expressing RET germ-line mutations and identification of new signaling elements. Synonyms: 1,3-dihydro-3-[(4-hydroxyphenyl)methylene]-5,6-dimethoxy-2H-indol-2-one; RPI-1; RPI1; RPI 1. CAS No. 269730-03-2. Molecular formula: C17H15NO4. Mole weight: 297.31.
RPI856 A
RPI856 A is a retrovirus protease inhibitor produced by Streptomyces sp. AL-322. It strongly inhibits in vitro HIV-1 protease and HTLV-I protease both derived from recombinant Escherichia coli. Synonyms: RPI856A; RPI-856 A. Molecular formula: C43H61N7O13. Mole weight: 884.
RPI856 B
RPI856 B is a retrovirus protease inhibitor produced by Streptomyces sp. AL-322. It strongly inhibits in vitro HIV-1 protease and HTLV-I protease both derived from recombinant Escherichia coli. Synonyms: RPI856B; RPI-856 B. Molecular formula: C43H61N7O13. Mole weight: 884.
RPI856 C
RPI856 C is a retrovirus protease inhibitor produced by Streptomyces sp. AL-322. It strongly inhibits in vitro HIV-1 protease and HTLV-I protease both derived from recombinant Escherichia coli. Synonyms: RPI856Cl RPI-856 C. Molecular formula: C39H56N6O10. Mole weight: 768.9.
RPI856 D
RPI856 D is a retrovirus protease inhibitor produced by Streptomyces sp. AL-322. It strongly inhibits in vitro HIV-1 protease and HTLV-I protease both derived from recombinant Escherichia coli. Synonyms: RPI856D; RPI-856 D. Molecular formula: C39H56N6O10. Mole weight: 768.9.
R)-(+)-Piperazine-2-carboxylic acid
5g Pack Size. Group: Building Blocks, Chiral Compounds, Organics, Piperazines. Formula: C5H10N2O2. CAS No. 31321-68-3. Prepack ID 59717481-5g. Molecular Weight 130.15. See USA prepack pricing.
5g Pack Size. Group: Building Blocks, Chiral Compounds, Pyrazines. Formula: C5H12Cl2N2O2. CAS No. 126330-90-3. Prepack ID 11959793-5g. Molecular Weight 203.07. See USA prepack pricing.
RPL-554
RPL 554 is a potent and selective PDE3/4 inhibitor for respiratory diseases, particularly in patients with asthma. Uses: A potent and selective pde3/4 inhibitor. Synonyms: [2-[6,7-Dihydro-9,10-dimethoxy-4-oxo-2-[(2,4,6-trimethylphenyl)imino]-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl]ethyl]-urea;UNII-3E3D8T1GIX;RPL-554; RPL-554; RPL-554; LS-193,855; LS 193,855; LS 193,855; LS193855; LS193855; LS-193855. Grades: ≥96%. CAS No. 298680-25-8. Molecular formula: C26H31N5O4. Mole weight: 477.56.
RPL8 protein (31-41)
RPL8 protein (31-41) is a truncated fragment of RPL8 protein. RPL8 (Ribosomal Protein L8) is a Protein Coding gene. Diseases associated with RPL8 include Spermatogenic Failure 2 and Spermatogenic Failure 1. Among its related pathways are Viral mRNA Translation and HIV Life Cycle. Synonyms: Ribosomal Protein L8 (31-41).
RPR113228
RPR113228 is a farnesyl-protein transferase inhibitor produced by Chrysosporium lobatum. It has no inhibitory effect on squalene synthase. Synonyms: RPR-113228; RPR113228. Molecular formula: C30H49O9P. Mole weight: 584.7.
RPR-200765A
RPR-200765A is a potent and selective inhibitor of p38 MAP kinase (IC50 = 50 nM). It inhibits LPS-stimulated TNFalpha release both in vitro, from human monocytes (EC50 = 110 nM), and in vivo in Balb/c mice (ED50 = 6 mg/kg). At oral doses between 10 and 30 mg/kg/day it reduces the incidence and progression in the rat streptococcal cell wall (SCW) arthritis model when administered in either prophylactic or therapeutic dosing regimens. The compound, which is a mesylate salt and exists as a stable monohydrate, shows good oral bioavailabiltiy (F = 50% in the rat) and excellent chemical stability. The data from the SCW disease model suggests that RPR200765A could exhibit a profile of disease modifying activity in rheumatoid arthritis (RA) patients which is not observed with current drug therapies. Synonyms: RPR-200765; RPR200765; RPR 200765; RPR-200765A. CAS No. 218158-45-3. Molecular formula: C24H25FN4O4. Mole weight: 452.48.
RPR-200765A Mesylayte
RPR-200765A Mesylayte, a potent and selective inhibitor of p38 MAP kinase (IC50 = 50 nM), could exhibit a profile of disease modifying activity in rheumatoid arthritis (RA) patients which is not observed with current drug therapies. RPR-200765A inhibits LPS-stimulated TNFalpha release both in vitro, from human monocytes (EC50 = 110 nM), and in vivo in Balb/c mice (ED50 = 6 mg/kg). Synonyms: [2-[4-(4-fluorophenyl)-5-pyridin-4-yl-1H-imidazol-2-yl]-5-methyl-1,3-dioxan-5-yl]-morpholin-4-ylmethanone; RPR 200765A; RPR-200765 A; 218158-45-3 (RPR-200765, free base). Grades: >98%. CAS No. 218162-38-0. Molecular formula: C24H25FN4O4. Mole weight: 452.48.
RPR203494
RPR203494 is a pyrimidine analogue of the p38 inhibitor RPR200765A with an improved in vitro potency. Synonyms: RPR-203494; RPR 203494. Grades: 98%. CAS No. 218160-26-0. Molecular formula: C26H29FN6O4. Mole weight: 508.54.
RPR-260243
RPR-260243 is a selective activator of the Human Ether-ago-go-Related Gene (hERG) (IC50 = 58 nM). Uses: Selective activator of the human ether-ago-go-related gene (herg) cardiac k channel. Synonyms: RPR260243; RPR 260243; RPR-260243. (3R,4R)-4-[3-(6-methoxyquinolin-4-yl)-3-oxo-propyl]-1-[3-(2,3,5-trifluoro-phenyl)-prop-2-ynyl]-piperidine-3-carboxylic acid. Grades: ≥98%. CAS No. 668463-35-2. Molecular formula: C28H25F3N2O4. Mole weight: 510.51.
R-Pralatrexate
The R isometric form of Pralatrexate which is a folate analog used to treat relapsed or refractory peripheral T-cell lymphoma. Synonyms: Pralatrexate, (R)-; (R)-pralatrexate; 1320211-70-8; UNII-9CY33O2XLX; 9CY33O2XLX; L-Glutamic acid, N-(4-((1R)-1-((2,4-diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-; 1320211-70-8 (R-isomer); (4-((R)-1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoyl)-L-glutamic acid; SCHEMBL1889869; DTXSID001031315; AKOS040747299; PD132342; HY-117791; CS-0068078; Q27272363; (2S)-2-[[4-[(2R)-1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioic acid. Grades: > 95%. CAS No. 1320211-70-8. Molecular formula: C23H23N7O5. Mole weight: 477.48.
RprDefA
RprDefA is an antibacterial peptide isolated from Rhodnius prolixus. It has activity against gram-positive bacteria and gram-negative bacteria, and can also be used as an insecticide. Synonyms: R. prolixus defensin A; Ala-Thr-Cys-Asp-Leu-Phe-Ser-Phe-Arg-Ser-Lys-Trp-Val-Thr-Pro-Asn-His-Ala-Ala-Cys-Ala-Ala-His-Cys-Leu-Leu-Arg-Gly-Asn-Arg-Gly-Gly-Arg-Cys-Lys-Gly-Thr-Ile-Cys-His-Cys-Arg-Lys. Molecular formula: C200H322N70O53S6. Mole weight: 4747.51.
RprDefB
RprDefB is an antibacterial peptide isolated from Rhodnius prolixus. It has activity against gram-positive bacteria and gram-negative bacteria, and can also be used as an insecticide. Synonyms: R. prolixus defensin B; Ala-Thr-Cys-Asp-Leu-Leu-Ser-Phe-Arg-Ser-Lys-Trp-Val-Thr-Pro-Asn-His-Ala-Gly-Cys-Ala-Ala-His-Cys-Leu-Leu-Arg-Gly-Asn-Arg-Gly-Gly-His-Cys-Lys-Gly-Thr-Ile-Cys-His-Cys-Arg-Lys. Molecular formula: C196H317N69O53S6. Mole weight: 4680.46.
RprDefC
RprDefC is an antibacterial peptide isolated from Rhodnius prolixus. It has activity against gram-positive bacteria and gram-negative bacteria, and can also be used as an insecticide. Synonyms: R. prolixus defensin C; Ala-Thr-Cys-Asp-Leu-Phe-Ser-Phe-Arg-Ser-Lys-Trp-Val-Thr-Pro-Asn-His-Ala-Gly-Cys-Ala-Ala-His-Cys-Ile-Phe-Leu-Gly-Asn-Arg-Gly-Gly-Arg-Cys-Val-Gly-Thr-Val-Cys-His-Cys-Arg-Lys. Molecular formula: C200H312N66O53S6. Mole weight: 4681.45.
rProtein A (4xZ), BioSeparation
BioSeparation rProtein A (4xZ) is a synthetic derivative of the native protein A molecule, produced by recombinant expression in E. coli and purified using a highly efficient, immunoglobulin-free process. rProtein A (4xZ) contains four identical copies of an Fc region-binding domain assembled in a single 29.88kD polypeptide, and can be coupled to solid supports to produce affinity media suitable for antibody capture and elution under standard conditions. Protein A is an immunoglobulin-binding cell wall protein naturally produced by Staphylococcus aureus and widely used as a generic ligand for the purification of monoclonal and recombinant antibodies. Group: Molecular Biology. US Biological Life Sciences.
Worldwide
rProtein A Agarose Rapid Flow, BioSeparation
BioSeparation rProtein A Rapid Flow is an affinity medium coupled with Biomedal rProtein A (4xZ) and designed for immunoglobulin capture and purification. ProPure® rProtein A Rapid Flow medium is compatible with chromatography systems such as ÄKTA or FPLC, providing high binding capacity and a cost-efficient purification process. Group: Molecular Biology. US Biological Life Sciences.
Worldwide
rProtein A-Cys, BioSeparation
BioSeparation rProtein A-Cys (4xZc) is a variant of rProtein A (4xZ) in which the C-terminal residue has been replaced with a cysteine residue that can be used for single-point coupling to solid supports, via the thioether bond, to produce affinity media suitable for antibody capture and elution. Like rProtein A (4xZ), rProtein A-Cys (4xZc) can also be attached to solid supports via multi-point coupling. rProtein A-Cys (4xZc) is produced by recombinant expression in E. coli and purified using a highly efficient, immunoglobulin-free process. rProtein A-Cys (4xZc) contains four identical copies of an Fc region-binding domain assembled in a single 29.87kD polypeptide. Group: Molecular Biology. US Biological Life Sciences.
Worldwide
rProtein A LCL Agarose, BioSeparation
BioSeparation rProtein A LCL Agarose is an affinity medium coupled with rProtein A (4xZ) and designed for immunoglobulin capture and purification. This affinity medium can be packed in standard chromatography columns for antibody purification at any production scale. Group: Molecular Biology. US Biological Life Sciences.
Worldwide
rProtein G Agarose Rapid Flow, BioSeparation
BioSeparation rProtein G Rapid Flow is an affinity medium coupled with rProtein G (3xC) and designed for immunoglobulin capture and purification. rProtein G Rapid Flow medium is compatible with chromatography systems such as ÄKTA or FPLC, providing high binding capacity and a cost-efficient purification process. Group: Molecular Biology. US Biological Life Sciences.
Worldwide
rProtein G, Rapid Flow, Agarose, BioSeparation
BioSeparation rProtein A Rapid Flow are ready-to-use cartridges pre-packed with 1ml of rProtein A Rapid Flow and compatible with chromatography systems such as ÄKTA or FPLC, providing high binding capacity and a cost-efficient purification process. They are designed for rapid and cost-efficient immunoglobulin capture and purification. Group: Molecular Biology. US Biological Life Sciences.
Worldwide
Rp,Rp-c-diAMPSS
Rp,Rp-c-diAMPSS is an analogue of c-diAMP, the bacterial second messenger, which has higher stability. It can be used to study ligand-receptor interactions and to increase the anti-tumor activity of therapeutic vaccines. Synonyms: Cyclic diadenosine monophosphorodithioate, Rp- isomers, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H24N10O10P2S2 (free acid). Mole weight: 690.6 (free acid).
Rp,Rp-c-diGMPSS
Rp,Rp-c-diGMPSS is an analogue of c-diGMP, the bacterial second messenger, with improved stability. It can be used to study ligand-receptor interactions. Synonyms: Cyclic diguanosine monophosphorodithioate, Rp- isomers, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1259875-41-6. Molecular formula: C20H24N10O12P2S2 (free acid). Mole weight: 722.6 (free acid).
RPS-027
RPS-027 is a double targeting ligands for prostate-specific membrane antigen (PSMA) (IC50 = 8 nM) promisingly used to treat prostate cancer. Uses: Th potential treatment prostate cancer. Synonyms: RPS 027; RPS027.
Rp,Sp-c-diAMPSS
Rp,Sp-c-diAMPSS is an analogue of c-diAMP, the bacterial second messenger, which has higher stability. It can be used to study ligand-receptor interactions. Synonyms: Cyclic diadenosine monophosphorodithioate, Rp- / Sp- isomers, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H24N10O10P2S2 (free acid). Mole weight: 690.6 (free acid).