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| Product | Description | |
|---|---|---|
| SpStrongylocin 1 | SpStrongylocin 1 is an antimicrobial peptide isolated from Strongylocentrotus purpuratus. It has activity against gram-positive bacteria and gram-negative bacteria. Alternative Names: Ile-Phe-Asn-Ser-Ile-Tyr-His-Arg-Lys-Cys-Val-Val-Lys-Asn-Arg-Cys-Glu-Thr-Val-Ser-Gly-His-Lys-Thr-Cys-Lys-Asp-Leu-Thr-Cys-Cys-Arg-Ala-Val-Ile-Phe-Arg-His-Glu-Arg-Pro-Glu-Val-Cys-Arg-Pro-Ser-Thr. |  |
| SpStrongylocin 2 | SpStrongylocin 2 is an antimicrobial peptide isolated from Strongylocentrotus purpuratus. It has activity against gram-positive bacteria and gram-negative bacteria. Alternative Names: Trp-Asn-Pro-Phe-Arg-Lys-Leu-Tyr-Arg-Lys-Glu-Cys-Asn-Asp-Val-Thr-Ser-Cys-Asp-Thr-Val-Ser-Gly-Val-Lys-Thr-Cys-Thr-Lys-Lys-Asn-Cys-Cys-His-Arg-Lys-Phe-Phe-Gly-Lys-Thr-Ile-Leu-Lys-Ala-Pro-Glu-Cys-Thr-Val-Ile-Ser. | |
| SPT-IN-1 | SPT-IN-1 (compound 1) is an orally active and potent SPT (serine palmitoyl transferase) inhibitor, with an IC50 of 5.19 nM for hSPT1. SPT-IN-1 can be used for type 2 diabetes and dyslipidemia research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1933533-18-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-125351. |  |
| Sp-TTPαS | Sp-TTP-α-S is used for regulation of TTP-responsive receptors and determination of their stereospecificity. Compared to TTP, it is much more stable. Uses: Antiviral agents. Alternative Names: 18883-94-8;Thymidine 5'-O-(1-thiotriphosphate);Dttp alphas;IMD4Y6027Y;[[(2~{R},3~{S},5~{R})-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-sulfanyl-phosphoryl] phosphono hydrogen phosphate;Dttp (alpha S);TTPalphaS;83199-32-0;Sp-TTP-.alpha.-S;UNII-IMD4Y6027Y;[hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphinothioyl] phosphono hydrogen phosphate;SCHEMBL2056849;EX-A7812Y;Thymidine-5'-O-(1-Thiotriphosphate);thymidine 5/'-O-(1-thiotriphosphate);Thymidine, 5'-P''-ester with thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(S)(OH)2), (S)-;CAS 18883-94-8;(Sp-)Thymidine- 5'- O- (.alpha.-thiotriphosphate);Thymidine, 5'-P''-ester with thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(S)(OH)2);[hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methoxy]phosphinothioyl] phosphono hydrogen phosphate;THIOTRIPHOSPHORIC ACID ((HO)2P(O)O(O)(O)P(OH)OP(S)(OH)2), 5'-MONOESTER WITH THYMIDINE;Thymidine, 5'-->P''-ester with thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(O)(OH)(SH));THYMIDINE, 5'->P''-ESTER WITH THIOTRIPHOSPHORIC ACID ((HO)2P(O)OP(O)(OH)OP(O)(OH)(SH));YQS. Grades: ≥ 95% by HPLC. CAS No. 83199-32-0. Molecular formula: C11H16BrN2O1 | |
| SPUTOLYSIN Reagent - CAS 578517 | SPUTOLYSIN Reagent - CAS 578517. Uses: For analytical and research use. CAS No. 3483-12-3. Catalog: AP3483123-A. |  |
| S-PVC | S-PVC. |  |
| S-PYRROLIDINYL BUTYNIL METHYL ESTER | S-PYRROLIDINYL BUTYNIL METHYL ESTER. CAS No. 358629-51-3. Molecular formula: C9H15NO3. Mole weight: 185.22. | |
| SQ109 | SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC50 for cell killing of 50±8 nM. SQ109, targets MmpL3, is an antitubercular agent. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 722041. CAS No. 502487-67-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14989. | |
| SQ22536 | SQ22536 is an effective adenylate cyclase (AC) inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 17318-31-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100396. | |
| SQ22536 | SQ22536 (9-(tetrahydrofuran-2-yl)-9h-purin-6-amine) is an inhibitor of adenylyl cyclase with an IC50 of 1.4 μM. It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets. Group: Inhibitors. Alternative Names: 9-(tetrahydrofuran-2-yl)-9h-purin-6-amine. CAS No. 17318-31-9. Pack Sizes: 10mg. Product ID: S8283. Formula: C9H11N5O. Smiles: C1CC(OC1)N2C=NC3=C(N=CN=C32)N. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| SQ 22536 | SQ 22536. Group: Biochemicals. Grades: Purified. CAS No. 17318-31-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| SQLE-IN-1 | SQLE-IN-1 (compound 19) is a squalene epoxidase (SQLE) inhibitor. SQLE-IN-1 inhibits the proliferation and migration of Huh7 cells. SQLE-IN-1 inhibits the cell cholesterol generation. SQLE-IN-1 increases the expression of PTEN and inhibits PI3K and AKT[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1019169-83-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160093. | |
| SQSTM1 / p62 Antibody [D16H4] | p62 (Sequestosome-1),p62 Ick ligand,p62/SQSTM1,SQSTM1,SQSTM1 / p62,SQSTM1/p62. Group: Antibodies. Alternative Names: p62 (Sequestosome-1),p62 Ick ligand,p62,SQSTM1. Pack Sizes: 20ul. Product ID: F0106. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Squalamine | Squalamine. Alternative Names: 3beta-N-1-(N-[3-(4-Aminobutyl)]- 1,3-diaminopropane)-7alpha,24R-dihydroxy-5alpha-cholestane 24-sulfate. CAS No. 148717-90-2. Purity: 95%+. Product ID: ACM148717902. Molecular formula: C34H65N3O5S. Mole weight: 628. IUPAC Name: [(3R,6R)-6-[(3S,5R,7R,8R,9S,10S,13R,14S,17R)-3-[3-(4-Aminobutylamino)propylamino]-7-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-yl] hydrogen sulfate. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Squalamine | Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson,s disease mouse models[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MSI-1256; ENT-01 free acid. CAS No. 148717-90-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-16468. | |
| Squalamine | Squalamine is a naturally derived broad-spectrum antibiotic that is predominantly derived from the livers of dogfish and other shark species. Squalamine is undergoing trials for treatment of non-small cell lung cancer (stage I/IIA) as well as general phase I pharmacokinetic studies. In 2005, the Food and Drug Administration granted squalamine Fast Track status for approval for treatment of age-related macular degeneration. However, the Genaera Corporation, the company that has done the most work with squalamine, discontinued trials for its use in treating prostate cancer and wet age-related macular degeneration in 2007. The Squalamine project was acquired by Ohr Pharmaceutical from the now liquidated Genaera, with the prospect of continuing the development of this drug to treat wet age-related macular degeneration. Alternative Names: MSI 1256; MSI-1256; MSI1256. Grades: ≥98% (HPLC). CAS No. 148717-90-2. Molecular formula: C34H65N3O5S. Mole weight: 627.96. | |
| Squalamine lactate | Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MSI-1256F. CAS No. 320725-47-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-16467. | |
| Squalane | Squalane. Group: Biochemicals. Alternative Names: 2,6,10,15,18,23-Hexamethyltetracosane. Grades: Highly Purified. CAS No. 111-01-3. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C30H62. US Biological Life Sciences. | Worldwide |
| Squalane | Squalane is commonly used as an emollient and moisturizer. Alternative Names: 2,6,10,15,19,23-hexamethyltetracosane. CAS No. 111-01-3. Molecular formula: C30H62. Mole weight: 422.81. | |
| Squalane | 100g Pack Size. Group: Building Blocks, Organics. Formula: [(CH3)2CH(CH2)3CH(CH3)(CH2)3CH(CH3)CH2CH2]2. CAS No. 111-01-3. Prepack ID 13053317-100g. Molecular Weight 422.81. See USA prepack pricing. |  |
| Squalane | Squalane. CAS No. 111-01-3. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  |
| Squalane-d62 | Squalane-d62 is the deuterium labeled Squalane[1]. Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 16514-83-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N7113S. | |
| Squalane-d62 | Isotope labelled Squalane is used as an emollient and moisturizer in cosmetic applications. Group: Biochemicals. Grades: Highly Purified. CAS No. 16514-83-3. Pack Sizes: 10mg, 25mg. Molecular Formula: C30D62, Molecular Weight: 485.2. US Biological Life Sciences. | Worldwide |
| Squalane-[d62] | Squalane-[d62]. Alternative Names: Squalane-d62; 2,6,10,15,19,23-Hexakis[(2H3)methyl](2H44)tetracosane. Grades: 95% atom D. CAS No. 16514-83-3. Molecular formula: C30D62. Mole weight: 485.2. | |
| Squalene | Squalene is a uniquely valuable biomaterial in pharmaceuticals. Its foremost role is as the core component of advanced emulsion adjuvants (MF59, AS03), which are critical for enhancing the efficacy of influenza and other vaccines. Its biocompatibility also supports applications in drug delivery and topical formulations. Grades: Pharmaceutical grade. Product ID: PE-0373. |  |
| Squalene | Squalene Inhibitor. Uses: Scientific use. Product Category: T4749. CAS No. 111-02-4. |  |
| Squalene | Squalene. Alternative Names: 2,6,10,14,18,22-Tetracosahexaene, 2,6,10,15,19,23-hexamethyl-; Skvalen; Sqalene; SQUALENE OIL; SQUALENE; SPINACENE; 2,6,10,15,19,23-HEXAMETHYL-2,6,10,14,18,22-TETRACOSAHEXAENE; 2,6,10,15,19,23-HEXAMETHYL-2, 6, 10, 14, 18, 22-TETRACOSAHEXENE. Grades: 95%. CAS No. 7683-64-9. Molecular formula: C30H50. Mole weight: 410.72. | |
| Squalene | Squalene. Alternative Names: 2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaene. CAS No. 111-02-4. Purity: 95%. Product ID: CI-OT-0037. Molecular formula: C30H50. Mole weight: 410.72 g/mol. IUPAC Name: (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Squalene | Squalene. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10g, 25g, 50g. US Biological Life Sciences. | Worldwide |
| Squalene | Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Super Squalene; trans-Squalene; AddaVax. CAS No. 111-02-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1214. | |
| Squalene-[d6] | Squalene-[d6] is the labelled form of Squalene, a natural triterpene that plays an important role in the synthesis of cholesterol, steroid hormones, and vitamin D in the human body. Squalene is commonly used as a biochemical precursor in the preparation of steroids. Squalene is also a natural moisturizer with low acute toxicity and is not significant human skin irritants or sensitizers. Alternative Names: (6E,10E,14E,18E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene-d6; 2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene-d6; Nikko Squalane EX-d6; Spinacene-d6; Squalen-d6; all-trans-Squalene-d6; trans-Squalene-d6; (all-E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene-d6; (E,E,E,E)-Squalene-d6. Grades: 95.16%; 97.4% atom D. Molecular formula: C30H44D6. Mole weight: 416.75. | |
| squalene-hopanol cyclase | The enzyme produces the cyclization products hopene (cf. EC 5.4.99.17) and hopanol from squalene at a constant ratio of 5:1. Group: Enzymes. Synonyms: squalene-hopene cyclase (ambiguous). Enzyme Commission Number: EC 4.2.1.129. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4970; squalene-hopanol cyclase; EC 4.2.1.129; squalene-hopene cyclase (ambiguous). Cat No: EXWM-4970. |  |
| squalene-hopene cyclase | The enzyme also produces the cyclization product hopan-22-ol by addition of water (cf. EC 4.2.1.129, squalene hopanol cyclase). Hopene and hopanol are formed at a constant ratio of 5:1. Group: Enzymes. Enzyme Commission Number: EC 5.4.99.17. CAS No. 76600-69-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5556; squalene-hopene cyclase; EC 5.4.99.17; 76600-69-6. Cat No: EXWM-5556. | |
| Squalene Liposome | The liposome contains squalene, which can be used as adjuvant to enhance the immune response. It is only for research purposes. Group: Liposomal vaccine or adjuvant. |  |
| squalene methyltransferase | Two isoforms differing in their specificity were isolated from the green alga Botryococcus braunii BOT22. TMT-1 gave more of the dimethylated form whereas TMT2 gave more of the monomethylated form. Group: Enzymes. Synonyms: TMT-1; TMT-2. Enzyme Commission Number: EC 2.1.1.262. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1867; squalene methyltransferase; EC 2.1.1.262; TMT-1; TMT-2. Cat No: EXWM-1867. | |
| squalene monooxygenase | A flavoprotein (FAD). This enzyme, together with EC 5.4.99.7 lanosterol synthase, was formerly known as squalene oxidocyclase. The electron donor is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: squalene epoxidase; squalene-2,3-epoxide cyclase; squalene 2,3-oxidocyclase; squalene hydroxylase; squalene oxydocyclase; squalene-2,3-epoxidase. Enzyme Commission Number: EC 1.14.14.17. CAS No. 9029-62-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0914; squalene monooxygenase; EC 1.14.14.17; 9029-62-3; squalene epoxidase; squalene-2,3-epoxide cyclase; squalene 2,3-oxidocyclase; squalene hydroxylase; squalene oxydocyclase; squalene-2,3-epoxidase. Cat No: EXWM-0914. | |
| squalene synthase | This microsomal enzyme catalyses the first committed step in the biosynthesis of sterols. The enzyme from yeast requires either Mg2+ or Mn2+ for activity. In the absence of NAD(P)H, presqualene diphosphate (PSPP) is accumulated. When NAD(P)H is present, presqualene diphosphate does not dissociate from the enzyme during the synthesis of squalene from farnesyl diphosphate (FPP). High concentrations of FPP inhibit the production of squalene but not of PSPP. Group: Enzymes. Synonyms: farnesyltransferase; presqualene-diphosphate synthase; presqualene synthase; squalene synthetase; farnesyl-diphosphate farnesyltransferase; SQS. Enzyme Commission Number: EC 2.5.1.21. CAS No. 9077-14-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2758; squalene synthase; EC 2.5.1.21; 9077-14-9; farnesyltransferase; presqualene-diphosphate synthase; presqualene synthase; squalene synthetase; farnesyl-diphosphate farnesyltransferase; SQS. Cat No: EXWM-2758. | |
| Squalestatin A | It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Alternative Names: Zaragozic acid A; squalestatin 1; Squalestatin; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-(4,6-dimethyl-2-octenoate), (5(2E,4S,6S),7S)-; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-; Squalestatin S1. Grades: >98% by HPLC. CAS No. 142561-96-4. Molecular formula: C35H46O14. Mole weight: 690.73. | |
| Squalestatin B | It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Alternative Names: L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-(4,6-dimethyl-2-octenoate), [5(2E,4S,6S),7S]-; Squalestatin 2; Squalestatin S2. CAS No. 142505-91-7. Molecular formula: C33H44O13. Mole weight: 648.70. | |
| Squalestatin C | It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Alternative Names: L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate, (7S)-; Squalestatin 3; Squalestatin H1. CAS No. 142505-92-8. Molecular formula: C25H30O13. Mole weight: 538.50. | |
| Squamatic acid | Squamatic acid. Alternative Names: Squamatsaure; 2-Hydroxy-4-methoxy-6-methyl-1,3-benzenedicarboxylic acid 1-(4-carboxy-3-hydroxy-2,5-dimethylphenyl) ester; 1,3-Benzenedicarboxylic acid, 2-hydroxy-4-methoxy-6-methyl-, 1-(4-carboxy-3-hydroxy-2,5-dimethylphenyl) ester; 2-Oxy-6-methoxy-4-methyl-isophthalsaeure-3-(3-oxy-2,5-dimethyl-4-carboxy-phenylester). CAS No. 569-36-8. Molecular formula: C19H18O9. Mole weight: 390.34. | |
| Squamolone | Squamolone. Alternative Names: 1-Pyrrolidinecarboxamide,2-oxo-(9CI). Grades: 98.0%. CAS No. 40451-67-0. Molecular formula: C5H8N2O2. Mole weight: 128.13. | |
| Squarain-carboxylate N-succinimidyl ester | Squarain-carboxylate N-succinimidyl ester. Alternative Names: SQ-NHS, AC1NOW1Z, CTK8E7978, 154161-81-6, 4-[(5-chloro-1,3,3-trimethylindol-1-ium-2-yl)methylidene]-2-[[5-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-1-ethyl-3,3-dimethylindol-2-ylidene]methyl]-3-oxocyclobuten-1-olate. CAS No. 154161-81-6. Purity: 96%. Product ID: ACM154161816. Molecular formula: C34H32ClN3O6. Mole weight: 614.09. IUPAC Name: 4-[(5-chloro-1,3,3-trimethylindol-1-ium-2-yl)methylidene]-2-[[5-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-1-ethyl-3,3-dimethylindol-2-ylidene]methyl]-3-oxocyclobuten-1-olate. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Squaric Acid | Crystalline, purity 99+%. Synonym: 3,4-Dihydroxy-3-cyclobutene-1,2-dione. CAS No. 2892-51-5. Pack Sizes: Typically in stock: 10g, 50g. Mole weight: 114.06. MP/BP: M.P. >300. Order No: FR-0532. |  Frinton Laboratories |
| Squarunkin A | Squarunkin A is a potent and selective UNC119-cargo interaction inhibitor, interrupting the UNC119A-myristoylated Src N-terminal peptide interaction (IC50=10 nM). Squarunkin A interferes with the activation of Src kinase in cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2101958-02-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-127002. | |
| Squaw Vine Powder | Squaw Vine Powder. |  CA, FL & NJ |
| SR-0813 | SR-0813 is a potent and selective ENL/AF9 YEATS domain inhibitor. SR-0813 has IC50 and EC50 values of 25 nM and 205 nM for ENL YEATS domain, respectively. SR-0813 has IC50 and EC50 values of 311 nM and 76 nM (CETSA) for AF9 YEATS domain, respectively. SR-0813 binds MAP3K19 with over 100-fold lower affinity (Kd=3.5 μM) than ENL YEATS (Kd=30 nM). SR-0813 can be used for the research of acute leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2597186-19-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145409. | |
| SR0987 | SR0987, a SR1078 analog, is a RORγt agonist, with an EC50 of 800 nM. SR0987 increases IL17 expression while repressing the expression of PD-1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 303126-97-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101454. | |
| SR1001 | SR1001 is a selective RORα and RORγt inverse agonist with Kis 172 and 111 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1335106-03-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-13421. | |
| SR1001 | Retinoic-acid-receptor-related orphan receptors (ROR) α and γ play a key role in the development of T-helper cells that produce interleukin-17 (TH17 cells), a subset of CD4+ T-cells that contribute to the inflammatory process and have been implicated in the pathology of autoimmune diseases. SR 1001 is a synthetic ligand specific for RORα and RORγ (Kis = 172 and 111 nM, respectively) that functions as an inverse agonist at these receptors. SR 1001 has been shown to suppress IL-17 promoter driven transcriptional activity by inhibiting the interaction of co-activators such as TRAP220 nuclear receptor box 2 peptide (IC50 = 117 nM) and SRC2 with RORα and RORγ as well as by increasing the recruitment of corepressors such as NCoR. At 5 μM, SR 1001 inhibits TH17 cell differentiation and IL-17A secretion in cultured splenocytes and human PBMCs. A 25 mg/kg dose of SR 1001 twice/day delays the onset and the severity of experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis. Alternative Names: SR 1001; SR-1001. Grades: >98%. CAS No. 1335106-03-0. Molecular formula: C15H13F6N3O4S2. Mole weight: 477.4. | |
| SR10221 | SR10221, a noncovalent inverse agonist of PPARγ, represses downstream PPARγ target genes leading to growth inhibition in bladder cancer cell lines[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1415321-64-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150308. | |
| SR1078 | SR1078 is a selective agonist of retinoic acid receptor-related orphan receptor α/γ (RORα/RORγ). SR1078 directly binds to the ligand binding domain of RORα and RORγ and increases the transcriptional activity of these receptors, leading to stimulation of RORα/γ target gene transcription[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1246525-60-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14422. | |
| SR-1114 | SR-1114 is a PROTAC degrader targeting ENL. SR-1114 degrades ENL in a CRBN-dependent manner and selectively downregulates ENL target genes. SR-1114 can promote the differentiation of acute myeloid leukemia cells. SR-1114 can be used in tumor research. (Pink: ENL ligand (HY-145409); Black: Linker; Blue: E3 Ligand (HY-14658))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2769141-82-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115881. | |
| SR11237 | SR11237 (BMS-649) GMP is SR11237 (HY-107413) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SR11237 is a RXR activator and lipid metabolism regulator that promotes the differentiation of induced neural stem cells into dopaminergic (TH-positive) neurons. SR11237 induces transcriptional regulation of lipogenic genes and cholesterol transporters, increases glycosaminoglycan release, and elevates total cellular triglyceride levels. SR11237 promotes heterodimerization of RXR with Nurr1, thereby enhancing tyrosine hydroxylase expression and facilitating dopamine release. SR11237 produces a synergistic effect when used in combination with bFGF/EGF. SR11237 is mainly used in studies related to osteoarthritis and Parkinson's disease[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-649. CAS No. 146670-40-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107413. | |
| SR 11237 | SR 11237. Group: Biochemicals. Grades: Purified. CAS No. 146670-40-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 11302 | SR 11302. Group: Biochemicals. Grades: Purified. CAS No. 160162-42-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| SR 11302 | SR 11302 is an inhibitor of activator protein-1 (AP-1), which is a transcription factor activity that displays antitumor effects in vivo. SR 11302 does not activate transcription from the retinoic acid response element (RARE) and displays no activity at retinoic acid receptors (EC50 > 1 μM for RARα, RARβ, RARγ and RXRα). Alternative Names: SR 11302; SR11302; SR-11302; (E,E,Z,E)-3-Methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid; (2E,4E,6Z,8E)-3-methyl-7-(4-methylphenyl)-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid. Grades: ≥98% by HPLC. CAS No. 160162-42-5. Molecular formula: C26H32O2. Mole weight: 376.54. | |
| SR 11302 | SR 11302. CAS No: 160162-42-5 |  Sarchem Laboratories New Jersey NJ |
| SR 11302 | SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor. SR 11302 is a retinoid that specifically inhibits AP-1 activity without activating the transcription of retinoic acid response element (RARE)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 160162-42-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15870. | |
| SR12418 | SR12418 is a REV-ERB-specific synthetic ligand with IC50s of 68 nM and 119 nM for REV-ERBα and REV-ERBβ, respectively. SR12418 can be used in experimental autoimmune encephalomyelitis (EAE) and colitis research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1801185-08-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148103. | |
| SR12813 | SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM[1][2]. SR12813 is also an efficient agonist of human pregnane X receptor (hPXR). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR)[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GW 485801. CAS No. 126411-39-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100793. | |
| SR 12813 | SR 12813. Group: Biochemicals. Grades: Purified. CAS No. 126411-39-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 140333 | SR 140333. Group: Biochemicals. Grades: Purified. CAS No. 153050-21-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 141716A | SR 141716A. Group: Biochemicals. Grades: Purified. CAS No. 158681-13-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 142948 | SR 142948. Group: Biochemicals. Grades: Purified. CAS No. 184162-64-9. Pack Sizes: 1mg, 10mg. US Biological Life Sciences. | Worldwide |
| SR 142948 | SR 142948 is an orally active and selective non-peptide neurotensin receptor (NT) antagonist with IC50s of 1.19 nM, 0.32 nM, 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. SR 142948 antagonizes NT-induced inositol monophosphate formation in HT-29 cells with an IC50 of 3.9 nM. SR 142948 blocks hypothermia, analgesia and steering behavior induced by NT in vivo. SR 142948 shows blood-brain permeability and can be used in study of psychiatric disorders[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 184162-64-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107664. | |
| SR142948A | SR142948A is an antagonist of non-peptide neurotensin (NT) receptor with a high affinity (IC50 = 0.32 - 3.96 nM; Ki < 10 nM). SR142948A has the effect of inhibiting bile acid secretion and some stimulant drugs. Uses: An antagonist of non-peptide neurotensin (nt) receptor with an effect of bile acid secretion inhibition. Alternative Names: SR 142948; SR 142948A; CHEMBL2431105; CHEMBL 2431105; CHEMBL-2431105; AC1NSKNX. Grades: ≥98 %. CAS No. 184162-64-9. Molecular formula: C39H51N5O6. Mole weight: 685.86. | |
| SR144528 | SR144528 is a potent and selective CB2 receptor antagonist with a Ki of 0.6 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 192703-06-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13439. | |
| SR 144528 | SR 144528. Group: Biochemicals. Alternative Names: (1S-endo)-5-(4-Chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-(1, 3, 3-trimethylbicyclo[2. 2. 1]hept-2-yl)-1H-Pyrazole-3-carboxamide. Grades: Highly Purified. CAS No. 192703-06-3. Pack Sizes: 5mg. Molecular Formula: C29H34ClN3O, Molecular Weight: 476.05. US Biological Life Sciences. | Worldwide |
| SR 146131 | SR 146131 is a potent, orally available, and selective nonpeptide (cholecystokinin 1) receptor agonist. Uses: Scientific research. Category: Signaling pathways. CAS No. 221671-61-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11077. | |
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