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| Product | Description | |
|---|---|---|
| SR17018 | SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC 50 of 97 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 2134602-45-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111454. |  |
| SR-18292 | SR-18292 is a PPAR gamma coactivator-1? (PGC-1?) inhibitor, which increases PGC-1? acetylation, suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095432-55-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101491. | |
| SR1848 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| SR18662 | SR18662 is a potent inhibitor of Krüppel-like factor five (KLF5) with an IC50 of 4.4 nM and an analogue of ML264 (HY-19994) with improved inhibitory potency against colorectal cancer cells. SR18662 can be used for the study of colorectal cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2505001-62-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-136530. | |
| SR18662 | SR18662 is an optimized anticancel agent based on ML264. SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitro and In Vivo. SR18662 showed improved efficacy in reducing the viability of multiple colorectal cancer cell lines. Flow cytometry analysis following SR18662 treatment showed an increase in cells captured in either S or G2-M phases of the cell cycle and a significant increase in the number of apoptotic cells, the latter a unique property compared with ML264 or SR15006. SR18662 treatment also reduces the expression of cyclins and components of the MAPK and WNT signaling pathways. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SR18662; SR-18662; SR 18662. Product Category: Others. Appearance: Solid powder. CAS No. 2505001-62-5. Molecular formula: C16H19Cl2N3O4S. Mole weight: 420.31. Purity: >98%. IUPACName: (E)-3-(3,4-dichlorophenyl)-N-(2-(4-(methylsulfonyl)piperazin-1-yl)-2-oxoethyl)acrylamide. Canonical SMILES: O=C(NCC(N1CCN(S(=O)(C)=O)CC1)=O)/C=C/C2=CC=C(Cl)C(Cl)=C2. Product ID: ACM2505001625. Alfa Chemistry ISO 9001:2015 Certified. |  |
| SR 202 | SR 202. Group: Biochemicals. Grades: Purified. CAS No. 76541-72-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| SR-202 | ?98% (HPLC), crystalline. Group: Fluorescence/luminescence spectroscopy. | |
| SR2211 | SR2211 is a potent, selective synthetic ROR? modulator and functions as an inverse agonist, with a Ki of 105 nM and an IC50 of ~320 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1359164-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16998. | |
| SR2211 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR2595 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR 2640 Hydrochloride | Potent and selective competitive leukotriene D4 and E4 receptor antagonist. Inhibits LTD4- but not histamine-induced guinea pig ileum and trachea contraction (pA2 = 8.7). Also inhibits LTD4- attenuation of human PMN chemotaxis. Group: Biochemicals. Alternative Names: 2-[[3- (2-Quinolinylmethoxy) phenyl]amino]benzoic acid hydrochloride. Grades: Highly Purified. CAS No. 146662-42-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 27417 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR 27897 | SR 27897. Group: Biochemicals. Grades: Purified. CAS No. 136381-85-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR-3029 | SR-3029 is a potent and selective casein kinase 1δ/1ε (CK1δ/ε) inhibitor with potent antiproliferative properties SR-3029 shoed IC50:= 97 nM in MTT assays against the human A375 melanoma cell line and have physical, in vitro and in vivo PK properties suitable for use in proof of principle animal xenograft studies against human cancer cell lines. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SR-3029; SR 3029; SR3029. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1454585-06-8. Molecular formula: C23H19F3N8O. Mole weight: 480.46. Purity: >98%. IUPACName: (6,7-Difluoro-1H-benzoimidazol-2-ylmethyl)-[9-(3-fluoro-phenyl)-2-morpholin-4-yl-9H-purin-6-yl]-amine. Canonical SMILES: FC1=CC(N2C=NC3=C(NCC4=NC5=CC=C(F)C(F)=C5N4)N=C(N6CCOCC6)N=C23)=CC=C1. Product ID: ACM1454585068. Alfa Chemistry ISO 9001:2015 Certified. Categories: SR 302 (VA). | |
| SR-3029 | SR-3029 is a potent and ATP competitive CK1? and CK1? inhibitor, with IC50s of 44 nM and 260 nM, respectively, and Kis of 97 nM for both kinases. Uses: Scientific research. Group: Signaling pathways. CAS No. 1454585-06-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100011. | |
| SR-31747 | SR-31747 is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 blocks cell proliferation by inhibiting sterol isomerase [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 132173-07-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13751. | |
| SR-318 | SR-318 is a potent and highly selective p38 MAPK inhibitor with IC50s of 5 nM, 32 nM and 6.11 ?M for p38?, p38? and p38?/?, respectively. SR-318 potently inhibits the TNF-? release in whole blood with an IC50 of 283 nM. SR-318 has anti-cancer and anti-inflammatory activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2413286-32-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135674. | |
| SR3335 | SR3335 (ML 176) is a selective ROR? inverse agonist that directly binds to ROR? with a Ki of 220 nM[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ML 176. CAS No. 293753-05-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14413. | |
| SR33805 | SR33805 is a potent Ca 2+ channel antagonist, with EC 50 s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively. SR33805 blocks L-type but not T-type Ca 2+ channels. SR33805 can be used for the research of acute or chronic failing hearts [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 121345-64-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136909. | |
| SR 33805 oxalate | SR 33805 oxalate. Group: Biochemicals. Grades: Purified. CAS No. 121346-33-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| SR 3576 | SR 3576. Group: Biochemicals. Grades: Purified. CAS No. 1164153-22-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR-3576 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR 3677 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR-3677 | SR-3677 is a potent and selective ROCK-II inhibitor with an IC50 of ~3 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1072959-67-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13300. | |
| SR 3677 dihydrochloride | SR 3677 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1072959-67-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR-4370 | SR-4370 is an inhibitor of HDAC, with IC50s of 0.13 ?M, 0.58 ?M, 0.006 ?M, 2.3 ?M, and 3.4 ?M for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1816294-67-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111400. | |
| SR-46349 hemifumarate salt | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR-4835 | SR-4835 Inhibitor. Uses: Scientific use. Product Category: T8325. CAS No. 2387704-62-1. |  |
| SR-4835 | SR-4835 is a potent, highly selective and ATP competitive dual inhibitor of CDK12/CDK13 (CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM). SR-4835 acts in synergy with DNA-damaging chemotherapy and PARP inhibitors and provokes triple-negative breast cancer (TNBC) cell death[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2387704-62-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130250. | |
| SR 48692 | SR 48692. Group: Biochemicals. Grades: Purified. CAS No. 146362-70-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 48692 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR 49059 | SR 49059 (SR-49059) is a potent, orally active, selective vasopressin V1a antagonist with a K i vaule of 1.4 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 150375-75-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18345. | |
| SR 49059 | SR 49059. Group: Biochemicals. Grades: Purified. CAS No. 150375-75-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| SR 57227A | solid. Group: Fluorescence/luminescence spectroscopy. | |
| SR 57227A | SR 57227A is a potent, orally active and selective 5-HT3 receptor agonist, with ability to cross the blood brain barrier. SR 57227A has affinities (IC 50 ) varying between 2.8 and 250 nM for 5-HT3 receptor binding sites in rat cortical membranes and on whole NG 108-15 cells or their membranes. Anti-depressant effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 77145-61-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-102064. | |
| SR 57227 hydrochloride | SR 57227 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 77145-61-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR-58611 | SR-58611. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (7S)-5,6,7,8-Tetrahydro-7-[[(R)-2-hydroxy-2-(3-chlorophenyl)ethyl]amino]-2-[(ethoxycarbonyl)methoxy]naphthalene;SR-58611;SR-58825A;amibegron. Product Category: Heterocyclic Organic Compound. CAS No. 121524-08-1. Molecular formula: C22H26ClNO4. Purity: 0.96. IUPACName: ethyl 2-[[(7S)-7-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-5,6,7,8-tetrahydronaphthalen-2-yl]oxy]acetate. Canonical SMILES: CCOC(=O)COC1=CC2=C(CCC(C2)NCC(C3=CC(=CC=C3)Cl)O)C=C1. Product ID: ACM121524081. Alfa Chemistry ISO 9001:2015 Certified. Categories: SR58611A. | |
| SR-58611A | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR 58611A hydrochloride | SR 58611A hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 121524-09-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 58894A | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR 59230A hydrochloride | SR 59230A hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1135278-41-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR-717 | SR-717 Inhibitor. Uses: Scientific use. Product Category: T8655. CAS No. 2375421-09-1. | |
| SR-717 | SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 ?M and 2.2 ?M in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. SR-717 is a stable cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic. Antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2375421-09-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131454. | |
| SR-717 lithium | SR-717 is an agonist of stimulator of interferon genes STING for treating cancer. SR-717 demonstrates broad interspecies and interallelic specificity. SR-717 functions as a direct cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic that induces the same "closed" conformation of STING. SR-717 displayed antitumor activity; promoted the activation of CD8+ T, natural killer, and dendritic cells in relevant tissues; and facilitated antigen cross-priming. SR-717 also induced the expression of clinically relevant targets, including programmed cell death 1 ligand 1 (PD-L1), in a STING-dependent manner. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SR-717 lithium; SR 717 lithium; SR717 lithium. Product Category: Agonists. Appearance: Solid powder. CAS No. 2375421-09-1. Molecular formula: C15H8F2LiN5O3. Mole weight: 351.2. Purity: >98%. IUPACName: lithium 2-(6-(1H-imidazol-1-yl)pyridazine-3-carboxamido)-4,5-difluorobenzoate. Canonical SMILES: O=C([O-])C1=CC(F)=C(F)C=C1NC(C2=NN=C(N3C=CN=C3)C=C2)=O.[Li+]. Product ID: ACM2375421091. Alfa Chemistry ISO 9001:2015 Certified. | |
| SR8278 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR8278 | SR8278 is a REV-ERBα antagonist and inhibits the REV-ERBα transcriptional repression activity with an EC 50 of 0.47 μM. SR8278 is used to regulate the metabolism in organisms and study biological rhythm. SR8278 also can be used for the research of Duchenne muscular dystrophy and Alzheimer's disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1254944-66-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14415. | |
| SR 8278 | SR 8278. Group: Biochemicals. Alternative Names: 1,2,3,4-Tetrahydro-2-[[5-(methylthio)-2-thienyl]carbonyl]-3-isoquinolinecarboxylic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 1254944-66-5. Pack Sizes: 10mg. Molecular Formula: C18H19NO3S2, Molecular Weight: 361.48. US Biological Life Sciences. | Worldwide |
| SR9009 | SR9009 is a REV-ERBα/β agonist with IC 50 s of 670 nM and 800 nM for REV-ERBα and REV-ERBβ, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1379686-30-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16989. | |
| SR9011 | SR9011 is a REV-ERBα / β agonist with IC 50 s of 790 nM and 560 nM for REV-ERBα and REV-ERBβ, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1379686-29-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16988. | |
| SR9011 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR9011 hydrochloride | SR9011 hydrochloride is a REV-ERBα / β agonist with IC 50 s of 790 nM and 560 nM for REV-ERBα and REV-ERBβ, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 2070014-94-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16988A. | |
| SR9238 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR9243 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SR9243 | SR9243 is a liver-X-receptor (LXR) inverse agonist that induces LXR-corepressor interaction. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613028-81-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-16972. | |
| SR-95531 | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| SR95531 (Gabazine, GABAA Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531) | A selective, competitive antagonist of GABAA receptor (IC50 = 440nM) that does not affect pentobarbitone or etomidate- induced currents even at high concentrations (~100uM). Also shown to block glycine receptors, but with low affinity (Kb = 190uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 104104-50-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| SR 95531 hydrobromide | SR 95531 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 104104-50-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| S(?)-Raclopride (+)-tartrate salt | >97%, solid. Group: Fluorescence/luminescence spectroscopy. | |
| sRANKL human | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| sRank Ligand from rat | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| sRank Receptor human | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| SRC1 (627-786), biotin,His tagged human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| SRC1 (627-786), biotin, untagged human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| SRC1 (627-786),His tagged human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| SRC1, untagged human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| SRC-3-IN-2 | SRC-3-IN-2 (SI-12 6c)is an orally active steroid receptor coactivator 3 ( SRC-3 ) inhibitor. SRC-3-IN-2 has antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3074959-44-4. Pack Sizes: 1 mg. Product ID: HY-163469. | |
| SRC, active, GST tagged from Rous sarcoma virus | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| SRC, active, GST tagged human | recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Src human | ?90% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution, histidine-tagged. Group: Fluorescence/luminescence spectroscopy. | |
| Src I1 | Src I1. Group: Biochemicals. Grades: Purified. CAS No. 179248-59-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
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