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| Product | Description | |
|---|---|---|
| S-Methylglutathione | Cas No. 2922-56-7. Mole weight: 321.35. |  |
| S-Methylglutathione | S-Methylglutathione. Group: Biochemicals. Grades: Highly Purified. CAS No. 2922-56-7. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C11H19N3O6S. US Biological Life Sciences. |  Worldwide |
| S-Methylglutathione | S-Methylglutathione is an S-substitued glutathione and a stronger nucleophile than GSH [1]. S-Methylglutathione has inhibitory effect on glyoxalase 1 [2]. Uses: Scientific research. Group: Peptides. CAS No. 2922-56-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-W009177. |  |
| S-Methylisothiourea hemisulfate salt | (S)-Methylisothiourea sulfate is a more potent than NMMA as an inhibitor of inducible nitric oxide synthetase (iNOS). The Ki values are 120, 200, and 160 nM using purified human iNOS, eNOS, and nNOS, respectively. Synonyms: methyl carbamimidothioate;sulfuric acid. Grades: ≥98% (HPLC). CAS No. 867-44-7. Molecular formula: C4H14N4O4S3. Mole weight: 139.19. | |
| S-Methylisothiourea sulfate | S-Methylisothiourea sulfate is a potent, selective and competitive inhibitor of inducible nitric oxide synthase (iNOS). S-Methylisothiourea sulfate exerts beneficial effects in rodent models of septic shock [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 867-44-7. Pack Sizes: 10 mM * 1 mL; 25 mg. Product ID: HY-79457. | |
| S-Methylisothiouronium sulfate | S-Methylisothiouronium sulfate. Group: Biochemicals. Alternative Names: 2-Methyl-2-thiopseudourea sulfate. Grades: Highly Purified. CAS No. 867-44-7. Pack Sizes: 500g, 1Kg, 2Kg, 5kg, 10kg. Molecular Formula: C4H12N4S2·H2SO4. US Biological Life Sciences. | Worldwide |
| S-Methyl-L-cysteine | S-Methyl-L-cysteine, a theurapeutic for neurodegenerative diseases, is a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with antioxidative, neuroprotective, and anti-obesity activities. Synonyms: S-Methyl-L-cysteine; NSC 15387; NSC15387; NSC-15387; (2R)-2-amino-3-methylsulfanylpropanoic acid; S-11C-methyl-L-cysteine; S-methylcysteine; S-methylcysteine, (DL-Cys)-isomer; S-methylcysteine, (L-Cys)-isomer; S-methylcysteine, hydrochloride, (L-Cys)-isomer. Grades: 98%. CAS No. 1187-84-4. Molecular formula: C4H9NO2S. Mole weight: 135.18. | |
| S-Methyl-L-cysteine | S-Methyl-L-cysteine. CAS No: 1187-84-4 |  Sarchem Laboratories New Jersey NJ |
| S-Methyl-L-cysteine | S-Methyl-L-cysteine is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with antioxidative, neuroprotective, and anti-obesity activities. Uses: Scientific research. Group: Natural products. Alternative Names: L-S-Methylcysteine. CAS No. 1187-84-4. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-B2188. | |
| S-Methyl-L-cysteine | S-Methyl-L-cysteine. Uses: Peptide synthesis. Additional or Alternative Names: (R)-2-Amino-3-(methylmercapto)propionic acid, SMLC. Product Category: Amino Acids. CAS No. 1187-84-4. Molecular formula: CH3SCH2CH(NH2)CO2H. Mole weight: 135.18. Canonical SMILES: CSC[C@H](N)C(O)=O. ECNumber: 214-701-6. Product ID: ACM1187844. Alfa Chemistry ISO 9001:2015 Certified. Categories: S-Methylcysteine. |  |
| S-Methyl-L-cysteine-d3 | S-Methyl-L-cysteine-d3. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| S-Methyl-L-Cysteine-S-oxide | S-Methyl-L-Cysteine-S-oxide is an alliin analogue. Synonyms: 2-Amino-3-methylsulfinylpropanoic acid. Grades: > 95%. CAS No. 6853-87-8. Molecular formula: C4H9NO3S. Mole weight: 151.19. | |
| S-Methyl-L-thiocitrulline acetate | S-Methyl-L-thiocitrulline is a potent nitric oxide synthase (NOS) inhibitor with selectivity for neuronal isoform versus eNOS and iNOS (Ki = 1.2, 11, and 40 nM for nNOS, eNOS, and iNOS, respectively). Synonyms: H-ThioCit(S-Me)-OH AcOH; L-Ornithine, N5-[imino(methylthio)methyl]-, acetate (1:1); L-Ornithine, N5-[imino(methylthio)methyl]-, monoacetate; (S)-2-Amino-5- ( (imino (methylthio)methyl)amino)pentanoic acid acetate. Grades: ≥95%. CAS No. 174063-92-4. Molecular formula: C9H19N3O4S. Mole weight: 265.33. | |
| S-Methyl-L-thiocitrulline acetate salt | ?98% (TLC). Group: Fluorescence/luminescence spectroscopy. |  |
| S-Methyl-L-thiocitrulline dihydrochloride | S-Methyl-L-thiocitrulline is a new potent nitric oxide synthase inhibitor for treatment of cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 156719-39-0. Pack Sizes: 10mg, 25mg, 100mg, 250mg. Molecular Formula: C7H15N3O2S HCl. US Biological Life Sciences. | Worldwide |
| S-Methyl-L-thiocitrulline, Dihydrochloride - CAS 209589-59-3 | A cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC?? = 300 nM) compared to the endothelial enzyme (IC?? = 5.4 μM). Group: Fluorescence/luminescence spectroscopy. | |
| S-methyl-L-thiocitrulline hydrochloride | Cas No. 209589-59-3. | |
| S-Methyl methanethiosulfonate | analytical standard. Group: Flavor and fragrance standards. | |
| S-Methyl N, N-Diethyldithiocarbamate | S-Methyl N,N-diethyldithiocarbamate (MeDDC) is a metabolite of the alcohol deterrent disulfiram. Uses: Enzyme inhibitors. Synonyms: N,N-Diethylcarbamodithioic Acid Methyl Ester; Diethyldithiocarbamic Acid Methyl Ester. Grades: > 95%. CAS No. 686-07-7. Molecular formula: C6H13NS2. Mole weight: 163.31. | |
| s-Methyl-N,N-diethyldithiocarbamate sulfoxide | s-Methyl-N,N-diethyldithiocarbamate sulfoxide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N,N-Diethyl-1-(methylsulfinyl)methanethioamide. Product Category: Heterocyclic Organic Compound. CAS No. 145195-14-8. Molecular formula: C6H13NOS2. Mole weight: 179.3. Product ID: ACM145195148. Alfa Chemistry ISO 9001:2015 Certified. | |
| S-Methyl-N,N-diethyldithiocarbamate sulfoxide | S-Methyl-N,N-diethyldithiocarbamate sulfoxide. Group: Biochemicals. Alternative Names: N, N-Diethyl-1- (methylsulfinyl) methanethioamide. Grades: Highly Purified. CAS No. 145195-14-8. Pack Sizes: 50mg. Molecular Formula: C6H13NOS2. US Biological Life Sciences. | Worldwide |
| S-Methyl-N,N-diethylthiocarbamate | S-Methyl-N,N-diethylthiocarbamate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| S-Methyl-N,N-diethylthiocarbamate Sulfone | A dioxygenated metabolite of Disulfiram (Antabuse) capable of in vitro inactivation of liver mitochondrial aldehyde dehydrogenase (EC 1.2.1.3, ALDH) with higher reactivity than the monooxygenated sulfoxide. Group: Biochemicals. Alternative Names: N, N-Diethyl-1- (methylsulfonyl) formamide. Grades: Highly Purified. CAS No. 155514-79-7. Pack Sizes: 5mg, 10mg, 25mg. US Biological Life Sciences. | Worldwide |
| S-Methyl-N,N-diethylthiocarbamate Sulfoxide | An oxygenated metabolite of Disulfiram (Antabuse) that is capable of in vitro inactivation of liver mitochondrial aldehyde dehydrogenase (EC 1.2.1.3, ALDH). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| S-methyl-penicillamine | An impurity of Penicillamine which is used to treat rheumatoid arthritis, Wilson's disease and a certain disorder which causes kidney stones (cystinuria). Grades: > 95%. Molecular formula: C6H13NO2S. Mole weight: 163.24. | |
| s-Methyl thiohexanoate | s-Methyl thiohexanoate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S-Methyl hexanethioate;S-(METHYLTHIO)HEXANOATE;METHYL THIOHEXANOATE;METHANETHIOL CAPROATE;FEMA 3862;Hexanethioic acid S-methyl ester. Product Category: Heterocyclic Organic Compound. CAS No. 2432-77-1. Molecular formula: C7H14OS. Mole weight: 146.25. Product ID: ACM2432771. Alfa Chemistry ISO 9001:2015 Certified. | |
| S-Methyl Tiopronin | S-Methyl Tiopronin is a metabolite of Tiopronin, which is used as an antidote against heavy metal poisoning. Uses: A metabolite of tiopronin. Synonyms: S-Methylthiola; S-Methylmercaptopropionylglycine; N-[2-(Methylthio)-1-oxopropyl]glycine; Rac-S-Methyl Tiopronin; N-[2-(Methylsulfanyl)propanoyl]glycine; Tiopronin S-Methyl Impurity; Glycine, N-[2-(methylthio)-1-oxopropyl]-. Grades: 95%. CAS No. 87254-91-9. Molecular formula: C6H11NO3S. Mole weight: 177.22. | |
| S-Methyl Tiopronin | A metabolite of Tiopronin. Group: Biochemicals. Alternative Names: N-[2-(Methylthio)-1-oxopropyl]glycine. Grades: Highly Purified. CAS No. 87254-91-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| S-Metolachlor Metabolite CGA 357704 | analytical standard. Group: Pesticides & metabolites standards. | |
| S-Metolachlor Metabolite CGA 368208 | analytical standard. Group: Pesticides & metabolites standards. | |
| S-Metolachlor Metabolite CGA 368208 | Synonyms: Sodium [(2-ethyl-6-me- thylphenyl) carbamoyl] methane sulfonate. CAS No. 1173021-76-5. Mole weight: 279.29. | |
| S-Metolachlor Metabolite CGA 37735 | analytical standard. Group: Pesticides & metabolites standards. | |
| s-Metolachlor metabolite cga 50720 | s-Metolachlor metabolite cga 50720. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S-Metolachlor Metabolite CGA 50720, 152019-74-4, CTK8E7572, AKOS009481030, N-(2-Ethyl-6-methylphenyl)-oxalamic acid, [(2-Ethyl-6-methylphenyl)amino]oxo-acetic acid. Product Category: Heterocyclic Organic Compound. CAS No. 152019-74-4. Molecular formula: C11H13NO3. Mole weight: 207.23. Purity: 0.96. IUPACName: 2-(2-ethyl-6-methylanilino)-2-oxoacetic acid. Canonical SMILES: CCC1=CC=CC(=C1NC(=O)C(=O)O)C. Product ID: ACM152019744. Alfa Chemistry ISO 9001:2015 Certified. | |
| S-Metolachlor Metabolite CGA 50720 | Synonyms: N-(2-Ethyl-6-methyl phenyl) oxamic acid. CAS No. 152019-74-4. Molecular formula: C11H13NO3. Mole weight: 207.23. | |
| S-Metolachlor Metabolite CGA 50720 | analytical standard. Group: Pesticides & metabolites standards. | |
| S-(+)-Mexiletine hydrochloride | S-(+)-Mexiletine hydrochloride. Group: Biochemicals. Alternative Names: (2S)-1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride; (+)-(S)-Mexiletine hydrochloride; (+)-Mexiletine hydrochloride. Grades: Highly Purified. CAS No. 81771-85-9. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C11H18ClNO. US Biological Life Sciences. | Worldwide |
| SMF | SMF. Group: Polymers. |  |
| SMI-16a | SMI-16a, a cell-permeable thiazolidinedione compound, is a selective and ATP-competitive Pim kinase inhibitor with IC50 values of 0.15, 0.02 and 48 μM for Pim1, Pim2 and PC3 cells, respectively. Synonyms: Pim1/2 Inhibitor IV; PIM1/2 Kinase Inhibitor VI; Pim1/2 Kinase Inhibitor IV; SMI-16a. (5Z)-5-[(4-propoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione; ST50842732; (Z)-5-(4-Propoxybenzylidene)thiazolidine-2,4-dione; 5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione; (5Z)-5-(4-propoxybenzylidene)-1,3-thiazolidine-2,4-dione. CAS No. 587852-28-6. Molecular formula: C13H13NO3S. Mole weight: 263.31. | |
| SMI481 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SMI 481 | SMI 481 is a small-molecule inhibitor (SMI) of the yeast phosphatidylinositol transfer proteins (PITP) Sec14 (IC50 values of 211 nM and 2.87 μM for Sec14 mediated [3H]PtdIns transfer in vitro, and Sec14 dependent cell growth inhibition of WT (CTY182, gray) strains, respectively). SMI 481 exhibits exquisite pathway selectivity in inhibiting phosphoinositide signaling in cells with >200-fold selectivity over other yeast Sec14-like transfer activities. Synonyms: SMI481; SMI-481 SMI 481; NPPM 6748-481; NPPM 6748481; NPPM6748481; NPPM-6748-481; (4-Chloro-3-nitrophenyl)(4-(2-fluorophenyl)piperazin-1-yl)methanone; 1-(4-chloro-3-nitrobenzoyl)-4-(2-fluorophenyl)piperazine; (4-chloro-3-nitrophenyl)[4-(2-fluorophenyl)piperazin-1-yl]methanone. Grades: 99%. CAS No. 432020-20-7. Molecular formula: C17H15ClFN3O3. Mole weight: 363.77. | |
| SMI-4a | Selective inhibitor of Pim-1 and Pim-2 protein kinases. Inducer of G1 phase cell cycle arrest. Inducer of p27Kip1. Inducer of apoptosis through the mitochondrial pathway. Inhibitor of the mammalian target of rapamycin C1 (mTORC1) pathway. Downregulates c-myc. Inhibitor of PRAS40 phosphorylation and mTOR activity. Potential anti-cancer compound. Blocks prostate cancer growth. Group: Biochemicals. Grades: Highly Purified. CAS No. 327033-36-3. Pack Sizes: 5mg. Molecular Formula: C11H6F3NO2S, Method for Determining. US Biological Life Sciences. | Worldwide |
| SMI-4a | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SMI-4a | SMI-4a, also called as TCS-PIM-1-4a, a thiazolidinedione compound, is a potent, selective ATP-competitive inhibitor against Pim protein kinase (IC50 = 24 nM against Pim-1 and 100 nM against Pim-2) with little or no activity against a panel of 58 other kin. Synonyms: SMI-4a; SMI 4a; SMI4a; (5E)-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dioneTCS-PIM-1-4aMS-1740; MS 1740; MS1740327033-36-35-{[3-(trifluoromethyl)phenyl]methylidene}-1,3-thiazolidine-2,4-dione. CAS No. 327033-36-3. Molecular formula: C11H6F3NO2S. Mole weight: 273.20. | |
| SMI-4a | SMI-4a (TCS-PIM-1-4a) is a poten, selective, cell-permeable and ATP-competitive Pim-1 inhibitor with an IC50 of 24 ?M and a Ki of 0.6 ?M. SMI-4a also inhibits Pim-2 (IC50 of 100 ?M), and does not significantly inhibit the other serine/threonine- or tyrosine-kinases. SMI-4a has anticancer activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TCS-PIM-1-4a. CAS No. 438190-29-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16576A. | |
| SMI-4a (5E/Z) -[[3- (Trifluoromethyl) phenyl]methylene]-2, 4-thiazolidinedione) | A selective, ATP-competitive inhibitor Pim-1 (IC50=21nm) and Pim-2 (IC50=100nm) protein kinases. Blocks mTORC1 activity via activation of AMPK. SMI-4a has been found to inhibit prostate cancer cell growth and induce G1 phase cell-cycle arrest in precursor T-cell lymphoblastic leukemia/lymphoma cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 327033-36-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| SMIFH2 | SMIFH2 is a formin specific inhibitor. SMIFH2 inhibits actin polymerization by Formins and affects the actin cytoskeleton[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 340316-62-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16931. | |
| SMIFH2 | SMIFH2. Group: Biochemicals. Grades: Purified. CAS No. 340316-62-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SMIFH2 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SMIFH2 | SMIFH2 is a formin specific inhibitor. SMIFH2 inhibits actin polymerization by Formins and affects the actin cytoskeleton. Uses: Designed for use in research and industrial production. Additional or Alternative Names: STK197413, ZINC01203437, SMIFH2, AC1M4GYW, MolPort-002-178-894, (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione, AKOS001651888, BIM-0040107.P001, (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione, 1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione, 340316-62-3. Product Category: Inhibitors. Appearance: Solid. CAS No. 340316-62-3. Molecular formula: C15H9BrN2O3S. Mole weight: 377.21. Purity: 0.96. IUPACName: (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione. Canonical SMILES: C1=CC(=CC(=C1)Br)N2C(=O)C(=CC3=CC=CO3)C(=O)NC2=S. Product ID: ACM340316623. Alfa Chemistry ISO 9001:2015 Certified. | |
| SMIFH2 | SMIFH2 is an inhibitor of formin homology 2 (FH2) domains. SMIFH2 prevents formin-mediated actin nucleation and barbed end elongation, disrupts formin-dependent actin cytoskeletal structures in fission yeast and mammalian NIH 3T3 fibroblasts. Synonyms: SMIFH-2; SMIFH 2; SMIFH2; 1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione; (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione. Grades: ≥99% by HPLC. CAS No. 340316-62-3. Molecular formula: C15H9BrN2O3S. Mole weight: 377.21. | |
| Smi I | One unit of the enzyme is the amount required to hydrolyze 1 μg of T7 DNA (SspI-digest) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme >95% of the dna fragments can be ligated and recut. ligation >95% in presence of 10% peg. Group: Restriction Enzymes. Purity: 1000U; 5000U. ATTT↑AAAT TAAA↓TTTA. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer O, BSA. Storage: -20°C. Form: Liquid. Source: Streptococcus milleri S. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: ET-1177RE. |  |
| Smilagenin | Smilagenin (SMI) is a small-molecule steroidal sapogenin from Anemarrhena asphodeloides and Pelargonium hortorum widely used in traditional Chinese medicine for treating chronic neurodegeneration diseases [1]. Smilagenin (SMI) improves memory of aged rats by increasing the muscarinic receptor subtype 1 (M1)-receptor density [2]. Smilagenin (SMI) attenuates Aβ(25-35)-induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD [3]. Uses: Scientific research. Group: Natural products. CAS No. 126-18-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106353. | |
| Smilagenin | Smilagenin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (25R)-SPIROSTAN-3BETA-OL; 25R,5BETA-SPIROSTAN-3BETA-OL; ISOSARSAPOGENIN; (25R)-Spirostan-3.β.-ol; (25R)-5beta-spirostan-3beta-ol; ISOSARSAPOGENINE; ESMILAGENIN; SMILAGENIN; ISOSARSASAPOGENIN. Product Category: Steroidal Compounds. CAS No. 126-18-1. Molecular formula: C27H44O3. Mole weight: 416.64. Purity: 0.98. IUPACName: (25R)-5β-spirostan-3β-ol. Canonical SMILES: CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)OC1. Density: 1.11g/cm³. ECNumber: 204-775-8. Product ID: ACM126181. Alfa Chemistry ISO 9001:2015 Certified. | |
| Smilagenin acetate | Smilagenin acetate is a sapogenin derivative extracted from patent US20030004147A1. Smilagenin acetate increases the expression of acetylcholine m2 receptors and can be used for the research of dementia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4947-75-5. Pack Sizes: 5 mg. Product ID: HY-N7421. | |
| Smilax sarsaparilla, ext. | Smilax sarsaparilla, ext. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Smilax sarsaparilla, ext.;SARSAPARILLA ROOT EXTRACT. Product Category: Heterocyclic Organic Compound. CAS No. 91770-66-0. Purity: 0.96. Product ID: ACM91770660. Alfa Chemistry ISO 9001:2015 Certified. | |
| SmiM I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. CAYNN↑NNRTG GTRNN↓NNYAC. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Sphingobacterium mizutae M. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; and 50% glycerol. Cat No: ET-1178RE. | |
| SMIP004 | SMIP004 a novel inducer of cancer-cell selective apoptosis of human prostate cancer cells, at low micromolar concentration it upregulated p27 in various prostate cancer cell lines. MTT assay in LNCaP-S14 cells: IC50=1.09 uM. Synonyms: N-(4-butyl-2-methylphenyl)acetamide143360-00-3N1-(4-butyl-2-methylphenyl)acetamideSMIP004; SMIP-004; SMIP 004. Acetamide , N- (4-butyl-2- methyl phenyl) -2- methyl -4-butylacetanilide N- (4-butyl-2- methyl phenyl) acetamide ZINC02565087Maybridge1_000068ACMC-1C0QFAC1MCN19MixCom1_0. CAS No. 143360-00-3. Molecular formula: C13H19NO. Mole weight: 205.15. | |
| S-Mirtazapine | S-Mirtazapine is an enantiomer of Mirtazapine, an antidepressant. R-Mirtazapine showed antinociceptive effects in acute thermal nociception, whereas S-Mirtazapine showed pronociceptive effects. Uses: Anti-anxiety agents. Synonyms: (S)-Org 3770; Esmirtazapine; Org 44-20; S-(+)-Mirtazapine; (S)-1,2,3,4,10,14b-Hexahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine; (+)-Mirtazapine; (14bS)-1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine ; (S)-6-Azamian. Grades: > 95%. CAS No. 61337-87-9. Molecular formula: C17H19N3. Mole weight: 265.35. | |
| SMK-17 | SMK-17 is a MEK1/2 inhibitor. It can inhibit MEK1 kinase activity in a non-ATP-competitive manner and it is highly selective to MEK1 and 2. SMK-17 can inhibit the growth of tumor cell lines in vitro. But it did not inhibit the phosphorylation of ERK5. SMK-17 selectively blocked the MAPK pathway signaling without affecting other signal pathways, which resulted in significant antitumor efficacy without notable side effects. Uses: Antitumor. Synonyms: SMK17; SMK 17; SMK17; N-(2-((2-chloro-4-iodophenyl)amino)-3,4-difluorophenyl)-4-(isopropylamino)piperidine-1-sulfonamide. Grades: 98%. CAS No. 765958-29-0. Molecular formula: C20H24ClF2IN4O2S. Mole weight: 584.85. | |
| SMN-C3 | SMN-C3 is an orally active SMN2 splicing modulator and has the potential to treat spinal muscular atrophy (SMA). Uses: Scientific research. Group: Signaling pathways. CAS No. 1449597-34-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112633. | |
| SMND-309 | SMND-309 is a novel derivative of salvianolic acid B, and has shown protective effects against rat cortical neuron damage in vitro and in vivo. Synonyms: SMND-309; SMND 309; SMND309. Grades: >98%. CAS No. 1065559-56-9. Molecular formula: C18H14O8. Mole weight: 358.3. | |
| Smo Antagonist, SA10 (4- ( (Benzo [c] [1, 2, 5] thiadiazole-4-sulfonamido) methyl -N- (3-phenylpropyl ) cyclohexane carboxamide) | SA10 inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC50 = 5uM). However, unlike SA1 and SA9, Smo antagonist SA10 does not directly bind to Smo. Inhibits the localization o Smo to cilia. Also treatment of Ptch1-/- MEFs with SA10 suppresses the beta-galactosidase activity (IC50 = 11.0uM) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| Smo Antagonist, SA1 (3-(3-(4-Fluorophenyl)-2, 5, 7-trimethylpyrazolo[1, 5a]pyrimidin-6-yl)-N-(4-(furan-2-yl)butan-2-yl)propanamide) | A Smoothened (Smo) antagonist. SA1 inhibits Hh pathway by interacting directly with Smo. Inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC50 = 3.1uM). Also inhibits the localization of Smo to cilia. Treatment of Ptch1-/- MEFs with SA1 suppresses the b-galactosidase activity (IC50 = 3.8uM) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| Smo Antagonist, SA9 (3- (3- (4-Fluorophenyl) -5-oxo-4, 5-dihydro-[1, 2, 4]triazolo[4, 3-a]quinazolin-1-yl-N- (3-methylphenethyl) propanamide) | SA9 inhibits Hh pathway by interacting directly with Smo. It inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC50 =19um). Induces the localization of Smo to cilia in ASZ1 cells, but not in IMCD3 cells. Also treatment of Ptch1-/- MEFs with SA9 suppresses the b-galactosidase activity (IC50 =1.0um) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| SMO-IN-2 | SMO-IN-2 (compound 1) is a potent smoothened (SMO) inhibitor with an IC 50 value of 123.4 nM for hedgehog (Hh) signaling pathway. SMO-IN-2 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1822355-27-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-150564. | |
| Smoke Point Standard | ASTM D 1322 / IP 57, 24.25 mm. Group: Cloud point standards. | |
| Smoke Tree Extract (Ratio) | Smoke Tree Extract (Ratio). Group: Others. Purity: 4:1~20:1. Smoke Tree Extract (Ratio). Cat No: EXTW-051. | |
| Smoothened Agonist, SAG - CAS 364590-63-6 | A cell-permeable Smoothened Agonist, SAG, CAS 364590-63-6, modulates the coupling of Smo with its downstream effector by interacting with the Smo heptahelical domain (KD = 59 nM). Group: Fluorescence/luminescence spectroscopy. | |
| Smoothened Agonist, SAG (N-Methyl-N- (3-pyridinylbenzyl) -N- (3-chlorobenzo [b]thiophene-2-carbonyl) -1, 4-diaminocyclohexane, SAG1.3 ) | A cell-permeable benzothiophene compound that modulates the coupling of Smo with its downstream effector by interacting with the Smo heptahelical domain (=59nM). Shown to induce Smo internalization. Shown to induce Hedgehog pathway activation (EC50= ?3nM in NIH 3T3-derived Shh-LIGHT2 cells) and counteracts Cyclopamine-KAAD inhibition of Smo. Reported to act as an activator at low concentrations and as an inhibitor at very high concentrations. Group: Biochemicals. Grades: Highly Purified. CAS No. 364590-63-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| SMPT | SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 112241-19-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-126405. | |
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