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Trospium chloride is an orally active, specific and competitive antagonist of muscarinic cholinergic receptors (mAChRs), with antimuscarinic activity. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10405-02-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-B0461.
Trospium Chloride
Tropine derivative with anticholinergic activity. Antispasmodic; used in treatment of urinary incontinence. Group: Biochemicals. Alternative Names: (1α,3 β , 5α )-3-[(2-Hydroxy-2, 2-diphenylacetyl)oxy]-spiro[8-azoniabicyclo[3. 2. 1]octane-8, 1'-pyrrolidinium] Chloride; Azoniaspiro; Keptan; Relaspium; Sanctura; Spasmex; Spasmo 3. Grades: Highly Purified. CAS No. 10405-02-4. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Trospium chloride Related Compound B
Trospium chloride Related Compound B. Uses: For analytical and research use. CAS No. 63516-30-3. Mole weight: 373.87. Catalog: AP63516303.
Trospium chloride Related Compound C
Trospium chloride Related Compound C. Uses: For analytical and research use. CAS No. 3464-71-9. Mole weight: 217.74. Catalog: AP3464719.
Trospium chloride (Standard)
Trospium (chloride) (Standard) is the analytical standard of Trospium (chloride). This product is intended for research and analytical applications. Trospium chloride is an orally active, specific and competitive antagonist of muscarinic cholinergic receptors (mAChRs), with antimuscarinic activity. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10405-02-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0461R.
Trospium-[d8] chloride
Trospium-[d8] chloride is the labelled analogue of Trospium Chloride, which is a derivative of tropine with anticholinergic property and could be used in the treatment of urinary incontinence as an antispasmodic. Synonyms: Trospium-d8 chloride. Molecular formula: C25H22D8ClNO3. Mole weight: 436.01.
Trospium-d8 Chloride
Tropine derivative with anticholinergic activity. Antispasmodic; used in treatment of urinary incontinence. Group: Biochemicals. Alternative Names: (1α,3 β , 5α )-3-[(2-Hydroxy-2, 2-diphenylacetyl)oxy]-spiro[8-azoniabicyclo[3. 2. 1]octane-8, 1'-pyrrolidinium]-d8 Chloride; Azoniaspiro-d8; Keptan-d8; Relaspium-d8; Sanctura-d8; Spasmex-d8; Spasmo 3-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Trotabresib
CC-90010 (compound 1) is a reversible and orally active BET inhibitor. CC-90010 is applied in the study for advanced solid tumors[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CC-90010. CAS No. 1706738-98-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137573.
Trovafloxacin
Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 147059-72-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0170.
Trovafloxacin mesylate
Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 147059-75-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103399.
Trovafloxacin Mesylate
Fluorinated quinolone antibacterial. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA. Group: Biochemicals. Alternative Names: 7-[(1α, 5α, 6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2, 4-difluorophenyl)-6-fluoro-1, 4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic Acid Methanesulfonate; CP 99219; CP 99219-27; Trovafloxacin Methanesulfonate; Trovafloxacin Monomethanesulfonate; Trovan. Grades: Highly Purified. CAS No. 147059-75-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
TROX-1
TROX-1 is a selective, orally active and brain-penetrant N-type calcium channel (Cav2.2) inhibitor with an IC50 value of 0.11 μM. TROX-1 exerts state-dependent and use-dependent inhibition, preferentially targets open/inactivated channels, blocks depolarization-associated calcium influx, and fully blocks calcium influx in rat dorsal root ganglion neurons. TROX-1 reverses inflammatory-induced hyperalgesia, nerve injury-induced allodynia. TROX-1 can be used for the research of pain[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1309601-26-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120751.
Troxacitabine
Troxacitabine. Group: Biochemicals. Alternative Names: 4-Amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one. Grades: Highly Purified. CAS No. 145918-75-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C8H11N3O4. US Biological Life Sciences.
Worldwide
Troxerutin
Troxerutin. Group: Biochemicals. Alternative Names: 3',4',7-?[O-(2-???)]??. Grades: Plant Grade. CAS No. 7085-55-4. Pack Sizes: 20mg. Molecular Formula: C33H42O19, Molecular Weight: 742.674999999999. US Biological Life Sciences.
Used in the treatment of venous disorders. Group: Biochemicals. Alternative Names: 2-[3,4-Bis(2-hydroxethoxy)phenyl]-3-[[6-O-(6-O-deoxy-a-L-mannopyranosyl)-B-D-glucopyranosyl]oxy]-5-hydroxy-7-(2-hydroxyethoxy)-4H-1-benzopyran-4-one, Posorutin, Ruven, Vastribil. Grades: Highly Purified. CAS No. 7085-55-4. Pack Sizes: 50mg. US Biological Life Sciences.
Troxerutin Impurity 1. Uses: For analytical and research use. CAS No. 6980-20-7. Molecular formula: C35H46O20. Mole weight: 786.73. Catalog: APB6980207.
Troxerutin Impurity 10
Troxerutin Impurity 10. Uses: For analytical and research use. CAS No. 72352-99-9. Molecular formula: C31H38O18. Mole weight: 698.63. Catalog: APB72352999.
Troxerutin Impurity 11
Troxerutin Impurity 11. Uses: For analytical and research use. CAS No. 125092-04-8. Molecular formula: C29H34O17. Mole weight: 654.57. Catalog: APB125092048.
Troxerutin Impurity 13
Troxerutin Impurity 13. Uses: For analytical and research use. CAS No. 50846-13-4. Molecular formula: C23H26O11. Mole weight: 478.45. Catalog: APB50846134.
Troxerutin Impurity 14
Troxerutin Impurity 14. Uses: For analytical and research use. CAS No. 23077-89-6. Molecular formula: C25H30O12. Mole weight: 522.5. Catalog: APB23077896.
Troxerutin Impurity 15
Troxerutin Impurity 15. Uses: For analytical and research use. CAS No. 23077-88-5. Molecular formula: C21H22O10. Mole weight: 434.4. Catalog: APB23077885.
Troxerutin Impurity 2
Troxerutin Impurity 2. Uses: For analytical and research use. CAS No. 862127-01-3. Molecular formula: C31H38O18. Mole weight: 698.63. Catalog: APB862127013.
Troxerutin Impurity 3
Troxerutin Impurity 3. Uses: For analytical and research use. CAS No. 13190-92-6. Molecular formula: C29H34O17. Mole weight: 654.57. Catalog: APB13190926.
Troxerutin Impurity 4
Troxerutin Impurity 4. Uses: For analytical and research use. CAS No. 13190-91-5. Molecular formula: C31H38O18. Mole weight: 698.63. Catalog: APB13190915.
Troxerutin Impurity 5
Troxerutin Impurity 5. Uses: For analytical and research use. Molecular formula: C35H46O20. Mole weight: 786.73. Catalog: APB12084.
Troxerutin Impurity 6
Troxerutin Impurity 6. Uses: For analytical and research use. Molecular formula: C35H46O20. Mole weight: 786.73. Catalog: APB12083.
Troxerutin Impurity 7
Troxerutin Impurity 7. Uses: For analytical and research use. CAS No. 13374-50-0. Molecular formula: C33H42O19. Mole weight: 742.68. Catalog: APB13374500.
Troxerutin Impurity 8
Troxerutin Impurity 8. Uses: For analytical and research use. CAS No. 23077-87-4. Molecular formula: C23H26O11. Mole weight: 478.45. Catalog: APB23077874.
Troxerutin Impurity 9
Troxerutin Impurity 9. Uses: For analytical and research use. CAS No. 23869-24-1. Molecular formula: C29H34O17. Mole weight: 654.57. Catalog: APB23869241.
Troxipide
Troxipide. Group: Biochemicals. Grades: Highly Purified. CAS No. 99777-81-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C15H22N2O4. US Biological Life Sciences.
Worldwide
Trp-Arg
Tryptophanyl-arginine is a dipeptide composed of tryptophan and arginine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Arginine, L-tryptophyl-; tryptophanyl-arginine; L-tryptophyl-L-arginine; (S)-2-((S)-2-Amino-3-(1H-indol-3-yl)propanamido)-5-guanidinopentanoic acid. Grade: ≥95% by HPLC. CAS No. 88831-09-8. Molecular formula: C17H24N6O3. Mole weight: 360.41.
A cell-permeable pyrazole derivative that acts as a selective blocker of the transient receptor potential cation channel TRPC3-medated ROCE (receptor-operated Ca2+ entry) and inhibits Carbachol-induced Ca2+ entry in TRPC3-expressing HEK293 cells (IC50 = 0.72uM; by Fura-2), while exhibiting much reduced potency against Stim1 and Orai1-coupled CRAC (Ca2+ release-activated Ca2+) channel-mediated SOCE (store-operated Ca2+ entry) in RBL-2H3 cells (IC50 = 13.08uM; by Fura-2). A great complement to Pyr2, Pyr 3, and Pyr6 in Ca2+ signaling studies. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
TRPC6-PAM-C20
TRPC6-PAM-C20 is a selective positive allosteric modulator (PAM) of TRPC6 channels. TRPC6-PAM-C20 is a potent enhancer of channel activation, enabling low basal concentrations of DAG to induce activation of the ion channel. TRPC6-PAM-C20 induces increases in intracellular Ca2+ concentrations ([Ca2+]i) in TRPC6-expressing HEK293 cells with an EC50 of 2.37 μM. TRPC6-PAM-C20 can be used as a valuable tool to selectively exaggerate TRPC6-dependent signals[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 667427-75-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136190.
Trp-Gly-Gly-OH. Group: Biochemicals. Alternative Names: L-Tryptophyl glycyl glycine. Grades: Highly Purified. CAS No. 20762-31-6. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
Trp-Gly-Gly-OH 99+% (TLC)
Trp-Gly-Gly-OH 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 20762-31-6. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
Trp-His-Trp-Leu-Gln-Leu
Trp-His-Trp-Leu-Gln-Leu. Synonyms: α1-Mating factor fragment 1-6. CAS No. 65418-88-4. Molecular formula: C45H59N11O8. Mole weight: 882.02.
TRPM4-IN-1
TRPM4-IN-1 (CBA) is a potent and selective inhibitor of the cation channel TRPM4, with an IC50 of 1.5 μM. TRPM4-IN-1 can be used for the research of cardiac diseases and prostate cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CBA. CAS No. 351424-20-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122605.
TRPM4-IN-2
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibitor with an IC50 value of 0.16 μM. TRPM4-IN-2 can be used for researching prostate cancer and colorectal cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NBA. CAS No. 667411-04-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128172.
TRPM8-IN-1
TRPM8-IN-1 (example 14) is an inhibitor of transient receptor potential melastatin-8 (TRPM8) channels, IC50<5 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1159996-20-9. Pack Sizes: 2 mg. Product ID: HY-108461.
A membrane permeable dihydroquinolinyloxo-isoindolinedione compound that acts as a potent and selective agonist of lysosomal mucolipin transient receptor potential (TRP) channel 1,2,3 (TRPML) in all mammalian cells. Does not appear to affect six other related TRP channels. Shown to rapidly activate whole-endolysosome TRPML-like current and induce lysosomal Ca2+ release (~10uM). Its activating action on whole-endolysosome is comparable to that of PI(3,5)P2 (1uM) with which it shows a synergistic effect. ML-SA1-induced Ca2+ responses are reportedly abolished by glycyl-L-phenylalanine 2-naphthylamide, induces osmotic lysis of lysosomes, and Bafilomycin A1, a V-ATPase inhibitor. Also reduces lactosylceramide and cholesterol accumulation and corrects trafficking defects in Niemann-Pick (NP) disease cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 332382-54-4. Pack Sizes: 25mg. US Biological Life Sciences.
TRPV2-selective blocker 1 is a TRPV2-selective blocker that inhibits calcium influx and ionic currents. TRPV2-selective blocker 1 exhibits an IC50 of 6.3 μM against rat TRPV2, and shows no activity against TRPV1, TRPV3 or TRPV4 channels. TRPV2-selective blocker 1 attenuates macrophage phagocytosis, LPS-induced macrophage migration, and calcium microdomains generated by peripheral TRPV2. TRPV2-selective blocker 1 is non-cytotoxic and can be used to investigate the function of TRPV2 during immune processes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2242724-49-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157131.
TRPV3 antagonist 74a
TRPV3 antagonist 74a is a potent and selective TRPV3 antagonist. TRPV3 antagonist 74a displays no significant activity against a panel of other ion channels. TRPV3 antagonist 74a can be used for the research of neuropathic pain[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1432051-63-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131868.
TRPV4 Antagonist II, HC-067047 (2-Methyl-1- (3-morpholinopropyl) -5-phenyl-N- (3- (trifluoromethyl) phenyl) -1H-pyrrole-3-carboxamide, Transient Receptor Potential Vanilloid-4 Antagonist II, HC067047)
A pyrrolocarboxamide compound that potently antagonizes TRP (transient receptor potential) family cation channel TRPV4 activity (IC50 = 17, 48, and 133nM, respectively, against mouse, human, or rat TRPV4 in whole cell voltage-gated current measurement) in a reversible manner, displaying much reduced potency against human ERG and TRPM8 (IC50 = 368 and 780nM, respectively) and little or no activity toward hKv1.3, hTRPA1, hTRPC5, hTRPV1/2/3/6, mTRPM7, mTRPV2, or rKv1.2. HC-067047 is efficacious (10mg/kg via i.p.) in reducing micturition (urination) frequency and increasing voided urine volume of mice and rats suffering from CPA-induced cystitis in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
TRPV4 Antagonist I, RN-1734 (2, 4-Dichloro-N-isopropyl-N- (2-isopropylaminoethyl) benzenesulfonamide, Transient Receptor Potential Vanilloid-4 Antagonist I, RN1734)
A cell-permeable benzenesulfonamide compound that selectively antagonizes TRPV4 agonist 4a-PDD-stimulated Ca2+ influx (IC50 = 2.3, 3.2 and 5.9uM, respectively, in HEK293 expressing human, rat, or mouse TRPV4) without affecting the activity of three other human TRP (transient receptor potential) channels, including capsaicin- activated TRPV1, camphor-activated TRPV3, and methanol-activated TRPM8 (IC50 >30uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 946387-07-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Trt-Cysteamine HCl
S-Tritylcysteamine Hydrochloride has been shown to have an antileukemic activity. Synonyms: 2-tritylsulfanylethanamine,hydrochloride; S-tritylcysteamine HCl; S-trityl-D-cysteine; S-tritylcysteamine hydrochloride; S-trityl-2-mercaptoethylamine hydrochloride. Grade: ≥ 95%. CAS No. 15297-43-5. Molecular formula: C21H21NS·HCl. Mole weight: 355.92.
Trt-cysteamine hydrochloride
Trt-cysteamine hydrochloride. Group: Biochemicals. Alternative Names: 2-(Tritylthio)ethylamine hydrochloride. Grades: Highly Purified. CAS No. 15297-43-5. Pack Sizes: 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
Trt-cysteamine hydrochloride 99+% (HPLC)
Trt-cysteamine hydrochloride 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 65°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. T↑TAA AAT↓T. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Tru9 I gene from Thermus ruber 9. Pack: 10 mM Tris-HCl-(pH 7.5); 50 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1183RE.
True Blue
True Blue (NCI 240899) is a fluorescent dye, as neuronal retrograde tracer (excitation wavelength 395-425 nm, barrier filter 450 nm). True Blue can label neuron and has no effects on neuronal survival[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NCI 240899. CAS No. 71431-30-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1161.
True Blue Diaceturate Salt
True Blue Diaceturate Salt is a fluorescent neuronal tracer. It is also a salt form of 2, 2- (1, 2-Ethene diyl ) bis [5-benzofurancarboximidam ide ] (CAS 65426-90-6) which can be used in biological study for identification of small moecule inhibitors of anthrax lethal factor. Group: Biochemicals. Alternative Names: 2, 2- (1, 2-Ethene diyl ) bis-5-benzofurancarboximidam ide compd. with N-Acetylglycine. Grades: Purified. CAS No. 108321-12-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??N?O? 2(C?H?NO?), Molecular Weight: 578.58. US Biological Life Sciences.
Worldwide
TRULI
TRULI (Lats-IN-1) is a potent and ATP-competitive inhibitor of Lats1 and Lats2 kinases. TRULI promotes Yap-dependent proliferation in postmitotic mammalian tissues[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lats-IN-1. CAS No. 1424635-83-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138489.
TRULI (Lats-IN-1)
TRULI inhibits both Lats1 and Lats2 with a IC50 of 0.2?nM, suppresses Yap phosphorylation, induces cell proliferation in several cell lines and tissues, and promotes the initial stages of proliferative regeneration of the sensory receptors in the inner ear. Group: Inhibitors. CAS No. 1424635-83-5. Pack Sizes: 5mg. Product ID: E1061. Formula: C18H14N4OS. Smiles: O=C(N=C1SC=CN1CC2=CC=CC=C2)C3=C[NH]C4=NC=CC=C34. Storage Conditions: 3 years -20°C powder.
United States; Europe
Truncated plakophilin-2 (581-590)
Truncated plakophilin-2 (581-590) is a truncated fragment of plakophilin-2 which is expressed in skin and cardiac muscle, where it functions to link cadherins to intermediate filaments in the cytoskeleton. This peptide can be used in Ovarian carcinoma related research.
TRV055 (TRV120055) is a G protein-biased agonist of angiotensin II type 1 receptors (AT1Rs). TRV120055 induces fibroblast proliferation, overexpression of collagen I and α-SMA, and stress fibre formation in human cardiac fibroblasts. TRV055 activates AT1 receptor/Gαq-mediated signaling pathways, upregulates TGF-β1 and p-ERK1/2. TRV055 induces collagen secretion in adult rat myofibroblasts at a level comparable to Ang II. TRV055 can be used to study the role of G protein-biased signaling of AT1Rs in regulating fibrotic responses[1]
TRV-120027
Synthetic analogue of endogenous peptide angiotensin II. An investigational drug for the treatment of heart failure and kidney disease. Synonyms: (2R)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]propanoic acid. CAS No. 1234510-46-3. Molecular formula: C43H67N13O10. Mole weight: 926.1.
TRV-120027
TRV120027, a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R), engages β-arrestins while blocking G-protein signaling[1]. TRV120027 induces acute catecholamine secretion through cation channel subfamily C3 (TRPC3) coupling, promotes the formation of a macromolecular complex composed of AT1R-β-arrestin-1-TRPC3-PLCγ at the plasma membrane. TRV120027 inhibits angiotensin II-mediated vasoconstriction and increases cardiomyocyte contractility. TRV120027 has the potential for the acute decompensated heart failure (ADHF) treatment[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TRV027. CAS No. 1234510-46-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2141.
TRV-120027 acetate
TRV-120027 acetate, a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R), engages β-arrestins while blocking G-protein signaling. TRV-120027 inhibits angiotensin II-mediated vasoconstriction and increases cardiomyocyte contractility. TRV-120027 has the potential for acute decompensated heart failure (ADHF) treatment. Synonyms: H-Sar-Arg-Val-Tyr-Ile-His-Pro-D-Ala-OH.CH3CO2H; sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-D-alanine acetic acid; D-Alanine, N-methylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-, acetate (1:1); TRV 027 acetate; TRV 120027 acetate; TRV120027 acetate. Grade: ≥95%. Molecular formula: C45H71N13O12. Mole weight: 986.14.
TRV-120027 TFA
TRV120027 TFA, a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R), engages β-arrestins while blocking G-protein signaling. TRV120027 TFA inhibits angiotensin II-mediated vasoconstriction and increases cardiomyocyte contractility. TRV120027 TFA has the potential for the acute decompensated heart failure (ADHF) treatment. Synonyms: H-Sar-Arg-Val-Tyr-Ile-His-Pro-D-Ala-OH.TFA; sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-D-alanine trifluoroacetate; D-Alanine, N-methylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-, trifluoroacetate (1:1); TRV 027 trifluoroacetate; TRV 120027 trifluoroacetate; TRV120027 trifluoroacetate; TRV120027 TFA; TRV 120027 TFA. Grade: 99%. Molecular formula: C45H68F3N13O12. Mole weight: 1040.10.
Trypacidin
It is produced by the strain of Aspergillus fumigatus. Trypacidin has anti-protozoal and spirochete effects, but the effect on the latter is weak. Synonyms: BRN 1299866; Methyl 4,6'-dimethoxy-6-methyl-3,4'-dioxo-3H-spiro[1-benzofuran-2,1'-cyclohexa[2,5]diene]-2'-carboxylate. Grade: ≥98% by HPLC. CAS No. 1900-29-4. Molecular formula: C18H16O7. Mole weight: 344.31.
Trypan Blue, Certified (Direct Blue 14, Niagara Blue 3B)
Trypan Blue is an azo based, hydrophilic, tetrasulfonated blue acid dye widely utilized for assessing cell viability. As an easy method to determining the viability of cells, Trypan Blue will stain dead cells with permeable membranes blue, while the dye is excluded by most living cells and their intact membranes thereby allowing visual determination of living versus dead cells. Although Trypan Blue is predominately used for assessing cell viability of cultured cells, other applications for this dye have been reported. In rat abdominal organ slices Trypan Blue has been utilized to determine cell viability as well as islet cell cluster cell viability from caprine pa...Cresotine Blue 3B; Diamine Blue 3B; Diamineblue; Diaphtamine Blue TH; Diazine Blue 3B; Diazol Blue 3B; Diphenyl Blue 3B; Direct Blue 14; Direct Blue 3B; Direct Blue M 3B; Hispamin Blue 3BX; Naphthylamine Blue; Niagara Blue; Niagara Blue 3B; Paramine Blue 3B; Pontamine Blue 3BX; Sodium Ditolyldisazobis-8-amino-1-naphthol-3,6-disulfonate; Trypan (Congo) Blue; Trypan Blue BPC; Trypane Blue; 3,3-[(3,3-Dimethyl[1,1-biphenyl]-4,4-diyl)bis(azo)]bis[5-amino-4-hydroxy-2,7-naphthalenedisulfonic Acid Tetrasodium. Grades: Certified Dye. CAS No. 72-57-1. Pack Sizes: 100g, 250g, 1Kg. Molecular Formula: C34H24N6O14S4Na4, Molecular Weight: 960.82. US Biological Life Sciences.
Worldwide
Trypan Blue (C.I.23850)
25g Pack Size. Group: Analytical Reagents, Diagnostic Raw Materials, Stains & Indicators. Formula: C34H24N6O14S4Na4. CAS No. 72-57-1. Prepack ID 45660104-25g. Molecular Weight 960.8. See USA prepack pricing.