A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Tubercidin is an adenosine analog with antiviral, antitrypanosomal, and antifungal properties. It inhibits DNA/RNA synthesis and other metabolic processes. Uses: 7-deaza-adenosine is an adenosine analog. Synonyms: 7-Deazaadenosine; Antibiotic XK 101-1; BRN 0038498; 7-Deaza ribo Adenosine; 7-β-D-Ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 4-Amino-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine; 6-Amino-9-D-ribofuranosyl-7-desazapurine; N7-Deazaadenosine; NQZ-003; NSC 56408; Sparsamycin A; Sparsomycin A; Tubercidine; U 10071. Grade: ≥98% by HPLC. CAS No. 69-33-0. Molecular formula: C11H14N4O4. Mole weight: 266.25.
Tubercidin
Tubercidin (7-Deazaadenosine) is an antibiotic obtained from Streptomyces tubercidicus. Tubercidin inhibits the growth of Streptococcus faecalis (8043) with an IC50 of 0.02 μM[1]. Tubercidin inhibits polymerases by incorporating DNA or RNA, thereby inhibiting DNA replication, RNA and protein synthesis[2]. Tubercidin is a weak inhibitor of adenosine phosphorylase, and interferes with the phosphorylation of adenosine and AMP[1]. Tubercidin has antiviral activity[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 7-Deazaadenosine. CAS No. 69-33-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100126.
Tubercidin
Tubercidin. Group: Biochemicals. Alternative Names: 4-Amino-7-( β -D-ribofuranosyl) pyrrolo[2, 3-d]pyrimidine; 6-Amino-9-D-ribofuranosyl-7-desazapurine; 7-Deazaadenosine; Antibiotic XK 101-1; N7-Deazaadenosine; NSC 5640Sparsamycin A; Sparsomycin A; Tubercidine; U 10071. Grades: Highly Purified. CAS No. 69-33-0. Pack Sizes: 10mg. Molecular Formula: C11H14N4O3, Molecular Weight: 250.25. US Biological Life Sciences.
Worldwide
tubercidin 5'-triphosphate
tubercidin 5'-triphosphate. Alternative Names: tubercidin 5'-triphosphate. CAS No. 10058-66-9. Product ID: ACM10058669. Alfa Chemistry - ISO 9001:32057 Certified.
tuberculosinol synthase
Only found in species of Mycobacterium that cause tuberculosis. In addition, it also gives isotuberculosinol in 1:1 mixture, cf. EC 3.1.7.9, isotuberculosinol synthase. Group: Enzymes. Synonyms: Rv3378c. Enzyme Commission Number: EC 3.1.7.8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3768; tuberculosinol synthase; EC 3.1.7.8; Rv3378c. Cat No: EXWM-3768.
Tuberculostearic Acid
Tuberculostearic Acid. Alternative Names: 10-methyloctadecanoic acid. CAS No. 542-47-2. Purity: 95% ethanol. Product ID: ACM542472. Molecular formula: C19H38O2. Mole weight: 298.50. Alfa Chemistry - ISO 9001:32057 Certified.
Tuberin
Tuberin is produced by the strain of Str.amakusaensis 10-101 and it is resistant to mycobacteria. Synonyms: N-Formyl-T-P-methoxystyrilamine; NSC 7382; N-trans-(p-Methoxystyryl)formamide. CAS No. 53643-53-1. Molecular formula: C10H11NO2. Mole weight: 177.20.
Tubermycin B
A simple phenazine produced by several species of pseudomonas and actinomycetes. It is a weakly active antibacterial compound that plays a role in the biocontrol of plant diseases by several pseudomonas strains. Synonyms: 1-Phenazinecarboxylic acid; 1-Carboxylic acid phenazine; NRRL B-1576; NSC 15851; BRN 0183818. Grade: >98% by HPLC. CAS No. 2538-68-3. Molecular formula: C13H8N2O2. Mole weight: 224.21.
Tuberostemonine
Tuberostemonine. Group: Biochemicals. Grades: Plant Grade. CAS No. 6879-1-2. Pack Sizes: 20mg. Molecular Formula: C22H33NO4, Molecular Weight: 375.5. US Biological Life Sciences.
Worldwide
Tuberostemonine
Tuberstemonine, coming from the roots of Stemona japonica, exhibited relatively higher intestinal permeabilities. It acts in part as an open-channel blocker at the crayfish neuromuscular junction. Uses: Anti-inflammatory/anti-bacterial/anti-allergy. Synonyms: (7aR,8aβ,11aβ,11bα,11cβ)-2β-[(2S,4S)-Tetrahydro-4-methyl-5-oxofuran-2-yl]-8β-ethyltetradecahydro-11β-methylfuro[2,3-h]pyrrolo[3,2,1-jk][1]benzoazepine-10-one; 2β-[(2S,4S)-Tetrahydro-4-methyl-5-oxofuran-2-yl]stenine; TUBERSTEMONINE(P). Grade: >98%. CAS No. 6879-1-2. Molecular formula: C22H33NO4. Mole weight: 375.51.
Tuberostemonine Trifluoroacetate
Tuberostemonine Trifluoroacetate. Group: Biochemicals. Pack Sizes: 5mg. US Biological Life Sciences.
Tubotaiwine is isolated from the herbs of Ervatamia divaricata. It shows selective activity against L. infantum. Uses: Analgesic activity. Synonyms: 2,16-Didehydrocondyfolan-16-carboxylic acid methyl ester; Methyl (14beta)-2,16-didehydrocondyfolan-16-carboxylate. Grade: 97.5%. CAS No. 6711-69-9. Molecular formula: C20H24N2O2. Mole weight: 324.4.
An intrinsic activity of α-tubulin involved in tubulin folding, division plane formation in prokaryotic cells and others. Group: Enzymes. Enzyme Commission Number: EC 3.6.5.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4717; tubulin GTPase; EC 3.6.5.6. Cat No: EXWM-4717.
Tubulin inhibitor 30
Tubulin inhibitor 30 (Compound 15) is a tubulin assembly inhibitor with an IC50 of 0.52 μM. Tubulin inhibitor 30 can induce ferroptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2873383-67-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151879.
tubulin-tyrosine ligase
L-Tyrosine is linked via a peptide bond to the C-terminus of de-tyrosinated α-tubulin (des-Tyrω-α-tubulin). The enzyme is highly specific for α-tubulin and moderately specific for ATP and L-tyrosine. L-Phenylalanine and 3,4-dihydroxy-L-phenylalanine are transferred but with higher Km values. Group: Enzymes. Enzyme Commission Number: EC 6.3.2.25. CAS No. 60321-03-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5743; tubulin-tyrosine ligase; EC 6.3.2.25; 60321-03-1. Cat No: EXWM-5743.
tubulinyl-Tyr carboxypeptidase
Active at neutral pH, from brain. Group: Enzymes. Synonyms: carboxypeptidase-tubulin; soluble carboxypeptidase; tubulin-tyrosine carboxypeptidase; tubulin carboxypeptidase; tubulinyltyrosine carboxypeptidase; tyrosinotubulin carboxypeptidase; tyrosyltubulin carboxypeptidase; TTCPase; brain I carboxypeptidase. Enzyme Commission Number: EC 3.4.17.17. CAS No. 73050-23-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4069; tubulinyl-Tyr carboxypeptidase; EC 3.4.17.17; 73050-23-4; carboxypeptidase-tubulin; soluble carboxypeptidase; tubulin-tyrosine carboxypeptidase; tubulin carboxypeptidase; tubulinyltyrosine carboxypeptidase; tyrosinotubulin carboxypeptidase; tyrosyltubulin carboxypeptidase; TTCPase; brain I carboxypeptidase. Cat No: EXWM-4069.
Tubuloside A
Tubuloside A. Group: Biochemicals. Grades: Plant Grade. CAS No. 112516-05-9. Pack Sizes: 20mg. Molecular Formula: C37H48O21, Molecular Weight: 828.76. US Biological Life Sciences.
Worldwide
Tubuloside A
Tubuloside A. Group: Biochemicals. CAS No. 112516-05-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Tubulysin
Tubulysin is a microtubule destabilizer that binds to the β-tubulin peptide site adjacent to the vinca alkaloid binding site and inhibits tubulin polymerization. Tubulysin induces apoptosis and exhibits antiproliferative activity against a variety of human cancer cells, including multidrug-resistant strains. Tubulysin can be conjugated to antibodies via a disulfide-containing quaternary ammonium linker for ADC synthesis. Tubulysin is applicable to tumor-related research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1943604-24-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-128914.
Tubulysin A
Tubulysin A is a novel antibiotic, which exhibits anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative activity. Tubulysins show very high cytotoxic activity against in vitro and in in vivo tumor models, especially against resistant tumor cell lines. Many representatives of these natural products are several orders of magnitude more potent than other available chemotherapeutics. Uses: Adcs cytotoxin. Synonyms: TubA; (αS,γR)-γ-[[[2-[(1R,3R)-1-(Acetyloxy)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[[(2R)-1-methyl-2-piperidinyl]carbonyl]amino]-1-oxopentyl][(3-methyl-1-oxobutoxy)methyl]amino]pentyl]-4-thiazolyl]carbonyl]amino]-4-hydroxy-α-methyl-benzenepentanoic Acid. Grade: ≥95% by HPLC. CAS No. 205304-86-5. Molecular formula: C43H65N5O10S. Mole weight: 844.07.
Tubulysin A
Tubulysin A (TubA) is an anticancer and antiangiogenic agent with anti-microtubule, anti-mitosis and anti-proliferative activity against a variety of cancer cells with IC50 values in the pmol range. It can induce apoptosis of cancer cells and has no effect on normal cells. Tubulysins are a group of potent cytotoxins consisting of nine members (A-I). Tubulysin A can synthesize ADC as ADC Cytotoxin[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TubA. CAS No. 205304-86-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15995.
Tubulysin B
Tubulysin B is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. It also has anti-fungal properties. Synonyms: (2S,4R)-2-Methyl-4-[2-[(1R,3R)-1-acetoxy-3-[[N-[[(2R)-1-methyl-2beta-piperidinyl]carbonyl]-L-isoleucyl](butanoyloxymethyl)amino]-4-methylpentyl]thiazole-4-ylcarbonylamino]-5-(4-hydroxyphenyl)pentanoic acid. Grade: ≥95%. CAS No. 205304-87-6. Molecular formula: C42H63N5O10S. Mole weight: 830.04.
Tubulysin C
Tubulysin C is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin C is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis. Synonyms: Tubulysin C; 205304-88-7; 072P54KU0L; UNII-072P54KU0L; (2S,4R)-4-[[2-[(1R,3R)-1-acetyloxy-4-methyl-3-[[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidine-2-carbonyl]amino]pentanoyl]-(propanoyloxymethyl)amino]pentyl]-1,3-thiazole-4-carbonyl]amino]-5-(4-hydroxyphenyl)-2-methylpentanoic acid; Benzenepentanoic acid, gamma-(((2-((1R,3R)-1-(acetyloxy)-4-methyl-3-(((2S,3S)-3-methyl-2-((((2R)-1-methyl-2-piperidinyl)carbonyl)amino)-1-oxopentyl)((1-oxopropoxy)methyl)amino)pentyl)-4-thiazolyl)carbonyl)amino)-4-hydroxy-alpha-methyl-, (alphaS. ga; SCHEMBL24218753; EX-A5466C; HY-N2347; AKOS040740942; CS-0021784; BENZENEPENTANOIC ACID. GAMMA.-(((2-((1R,3R)-1-(ACETYLOXY)-4-METHYL-3-(((2S,3S)-3-METHYL-2-((((2R)-1-METHYL-2-PIPERIDINYL)CARBONYL)AMINO)-1-OXOPENTYL)((1-OXOPROPOXY)METHYL)AMINO)PENTYL)-4-THIAZOLYL)CARBONYL)AMINO)-4-HYDROXY-.ALPHA.-METHYL-, (.ALPHA.S. GAMMA.R)-. Grade: 98%. CAS No. 205304-88-7. Molecular formula: C41H61N5O10S. Mole weight: 816.02.
Tubulysin D
Tubulysin D is a tetrapeptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. It displays potent antitumor activity and leads to cell cycle arrest and apoptosis by inhibiting tubulin polymerization with an IC50 of 1.7 μM. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range. Synonyms: (+)-Tubulysin D. Grade: ≥98%. CAS No. 309935-57-7. Molecular formula: C43H65N5O9S. Mole weight: 828.07.
Tubulysin IM-1
Tubulysin IM-1 is an ADC Cytotoxin and it is also a tubulin binder used as anti-microtubule toxin. Synonyms: ethyl (2S,4R)-4-(2-((1R,3R)-1-acetoxy-3-((tert-butoxycarbonyl)(methyl)amino)-4-methylpentyl)thiazole-4-carboxamido)-2-methyl-5-phenylpentanoate. Grade: 95%. Molecular formula: C32H47N3O6S. Mole weight: 601.80.
Tubulysin IM-2
Tubulysin IM-2 can be used in the synthesis of Tubulysin M. Tubulysin M is a Tubulysin D is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis. Tubulysin M is used as the cytotoxin in antibody-drug conjugates. Synonyms: 2-((1R,3R)-1-acetoxy-3-((2S,3S)-N,3-dimethyl-2-((R)-1-methylpiperidine-2-carboxamido)pentanamido)-4-methylpentyl)thiazole-4-carboxylic acid, TFA salt. Grade: 95%. Molecular formula: C28H42F3N4O7S. Mole weight: 635.72.
Tubulysin IM-3
Tubulysin IM-3 can be used in the synthesis of Tubulysin anologs. Tubulysin anologs is a class of microtubule-disrupting agents and can be used as cytotoxins in antibody-drug-conjugation (ADC). Synonyms: ethyl (2S,4R)-4-amino-2-methyl-5-phenylpentanoate hydrochloride. Grade: 95%. Molecular formula: C14H21NO2.HCl. Mole weight: 271.79.
Tubulysin M
Tubulysin M is a Tubulysin D analog with potential anti-cancer properties, used as the cytotoxic component in antibody-drug conjugates. Synonyms: (2S,4R)-4-{[(2-{(1R,3R)-1-Acetoxy-4-methyl-3-[methyl(N-{[(2R)-1-methyl-2-piperidinyl]carbonyl}-L-isoleucyl)amino]pentyl}-1,3-thiazol-4-yl)carbonyl]amino}-2-methyl-5-phenylpentanoic acid. Grade: ≥95%. CAS No. 936691-46-2. Molecular formula: C38H57N5O7S. Mole weight: 727.39.
Tubulysin M
Tubulysin M is a highly cytotoxic anti-microtubule toxin (anti-microtubule toxins) that is synthesized as an ADC cytotoxin (ADC Cytotoxin). Tubulysin M can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin M displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the low nanomolar range. Tubulysin M inhibits microtubule/tubulin polymerization and leads to cell cycle arrest and apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 936691-46-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7053.
Tucaresol
Tucaresol is an orally bioavailable immunopotentiatory drug that show to enhance T-helper-cell activity, with the induction of increased IL-2 and IFN-γ levels in mice and humans. Tucaresol has anti-HIV effect[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BWA589C. CAS No. 84290-27-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106755.
Tucatinib
Tucatinib (Irbinitinib) is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Irbinitinib; ARRY-380; ONT-380. CAS No. 937263-43-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16069.
Tucatinib hemiethanolate
Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Irbinitinib hemiethanolate; ARRY-380 hemiethanolate; ONT-380 hemiethanolate. CAS No. 1429755-56-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16069A.
Tucatinib Impurity 1
Tucatinib Impurity 1. Uses: For analytical and research use. Molecular formula: C15H21N5O2S. Mole weight: 335.43. Catalog: APB12028.
Tucatinib Impurity 10
Tucatinib Impurity 10. Uses: For analytical and research use. Molecular formula: C15H21N5O2. Mole weight: 303.37. Catalog: APB12035.
Tucatinib Impurity 11
Tucatinib Impurity 11. Uses: For analytical and research use. Molecular formula: C13H16N4O2S. Mole weight: 292.36. Catalog: APB12034.
Tucatinib Impurity 12
Tucatinib Impurity 12. Uses: For analytical and research use. Molecular formula: C24H22N8OS. Mole weight: 470.56. Catalog: APB12037.
Tucatinib Impurity 13
Tucatinib Impurity 13. Uses: For analytical and research use. Molecular formula: C27H22N8O3. Mole weight: 506.53. Catalog: APB12036.
Tucatinib Impurity 14
Tucatinib Impurity 14. Uses: For analytical and research use. Molecular formula: C26H24N8OS. Mole weight: 496.59. Catalog: APB12038.
Tucatinib Impurity 2
Tucatinib Impurity 2. Uses: For analytical and research use. CAS No. 937263-81-5. Molecular formula: C26H24N8O3. Mole weight: 496.53. Catalog: APB937263815.
Tucatinib Impurity 3
Tucatinib Impurity 3. Uses: For analytical and research use. CAS No. 937266-01-8. Molecular formula: C26H24N8OS. Mole weight: 496.59. Catalog: APB937266018.
Tucatinib Impurity 4
Tucatinib Impurity 4. Uses: For analytical and research use. CAS No. 2307628-67-5. Molecular formula: C21H17N7O. Mole weight: 383.42. Catalog: APB2307628675.
Tucatinib Impurity 5
Tucatinib Impurity 5. Uses: For analytical and research use. Molecular formula: C26H18D6N8O2. Mole weight: 486.57. Catalog: APB12029.
Tucatinib Impurity 6
Tucatinib Impurity 6. Uses: For analytical and research use. Molecular formula: C10H10N4O. Mole weight: 202.22. Catalog: APB12031.
Tucatinib Impurity 7
Tucatinib Impurity 7. Uses: For analytical and research use. Molecular formula: C21H22N8S. Mole weight: 418.52. Catalog: APB12030.
Tucatinib Impurity 8
Tucatinib Impurity 8. Uses: For analytical and research use. Molecular formula: C15H21N5O2S. Mole weight: 335.43. Catalog: APB12032.
Tucatinib Impurity 9
Tucatinib Impurity 9. Uses: For analytical and research use. Molecular formula: C13H17N5S. Mole weight: 275.37. Catalog: APB12033.
Tucatinib (Irbinitinib, ONT-380, Arry-380)
Tucatinib (Irbinitinib, ONT-380, ARRY-380) is an oral, potent, selective, reversible and ATP-competitive small-molecule inhibitor of ErbB-2 (also called HER2) with IC50s of 8 nM and 7 nM for ErbB-2 and p95 HER2, respectively in cell-based assays, showing ~500-fold selective for HER2 vs EGFR. It has potential antineoplastic activity. Group: Inhibitors. Alternative Names: Irbinitinib, ONT-380, ARRY-380. CAS No. 937263-43-9. Pack Sizes: 5mg. Product ID: S8362. Formula: C26H24N8O2. Smiles: CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)NC4=NC(CO4)(C)C)OC5=CC6=NC=NN6C=C5. Storage Conditions: 2 years -80 in solvent.
Tucidinostat (Chidamide) is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 (IC50s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Chidamide; HBI-8000; CS 055. CAS No. 1616493-44-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-109015.
Tucidinostat
Tucidinostat (Chidamide) is an effective and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8/11 (IC50: 733/432 nM), and shows no effect on HDAC4/5/6/7/9. Category: Active pharmaceutical ingredients. CAS No. 1616493-44-7. Product ID: API1616493447. Molecular formula: C22H19FN4O2. Mole weight: 390.41.
Tucidinostat (Chidamide)
Tucidinostat (Chidamide, HBI-8000, CS-055) is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively. Group: Inhibitors. Alternative Names: HBI-8000, CS-055. CAS No. 1616493-44-7. Pack Sizes: 5mg. Product ID: S8567. Formula: C22H19FN4O2. Smiles: C1=CC(=CN=C1)C=CC(=O)NCC2=CC=C(C=C2)C(=O)NC3=C(C=C(C=C3)F)N. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Tucidinostat-[d4]
Tucidinostat-[d4] is an isotope labelled compound of Tucidinostat. Chidamide is a newly designed histone deacetylase inhibitor that induces an antitumor effect in various cancer by increasing the acetylation levels of histone H3 and decreasing histone deacetylase (HDAC) activity, inducing apoptosis. It is a potential utility of Chidamide for the treatment of Myelodysplastic syndromes. Synonyms: N-(2-Amino-4-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propenyl]amino]methyl]-benzamide-d4; Chidamide-d4; HBI-800 D4. Grade: 98% by CP. Molecular formula: C22H15D4FN4O2. Mole weight: 394.43.
Tucotuzumab celmoleukin
Tucotuzumab celmoleukin (EMD 273066) is an immunocytokine. Tucotuzumab celmoleukin consists of the following components: an IgG1 monoclonal antibody targeting human EpCAM antigen, and two molecules of IL2. Tucotuzumab celmoleukin binds to EpCAM. Tucotuzumab celmoleukin exerts anti-tumor effects on colon adenocarcinoma in synergy with radiofrequency ablation. Tucotuzumab celmoleukin can be used in research related to colon adenocarcinoma and colon cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EMD 273066; huKS-IL2. CAS No. 339986-90-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991214.
Tuftsin
Tuftsin is a tetrapeptide located in the Fd fragment of the gamma-globulin molecule. Tuftsin is a macrophage/microglial activator. Synonyms: L-Arginine, L-threonyl-L-lysyl-L-prolyl-; L-Arginine, N2-[1-(N2-L-threonyl-L-lysyl)-L-prolyl]-; L-Threonyl-L-lysyl-L-prolyl-L-arginine; Tafcine; Taftsin; Taphcin; H-Thr-Lys-Pro-Arg-OH. Grade: 95%. CAS No. 9063-57-4. Molecular formula: C21H40N8O6. Mole weight: 500.59.
Tuftsin
Tuftsin is a tetrapeptide. Tuftsin is a macrophage/microglial activator. Uses: Scientific research. Category: Signaling pathways. CAS No. 9063-57-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0240.
Tuftsin 3TFA
Tuftsin is a tetrapeptide located in the Fd fragment of the gamma-globulin molecule. Tuftsin is a macrophage/microglial activator. Synonyms: L-Arginine, N2-[1-(N2-L-threonyl-L-lysyl)-L-prolyl]-, tris(trifluoroacetate) (salt); Acetic acid, trifluoro-, compd. with N2-[1-(N2-L-threonyl-L-lysyl)-L-prolyl]-L-arginine (3:1); H-Thr-Lys-Pro-Arg-OH.3TFA; L-threonyl-L-lysyl-L-prolyl-L-arginine trifluoroacetic acid; TKPR.3TFA. Grade: ≥95%. CAS No. 81019-03-6. Molecular formula: C21H40N8O6.3C2HF3O2. Mole weight: 842.66.
TUG-1375 is an agonist of free fatty acid receptor 2 (FFA2/GPR43), with a pKi of 6.69. TUG-1375 is inactive on FFA3, FFA4, PPARα, PPARγ, PPARδ, LXRα or LXRβ[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2247372-59-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112813.
TUG-424
TUG-424 is a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with an EC50 of 32 nM. TUG-424 significantly increases glucose-stimulated insulin secretion at 100 nM. TUG-424 may serve to explore the role of FFA1 in metabolic diseases such as diabetes or obesity[1]. TUG-424 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1082058-99-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-14363.
TUG-770
TUG-770 is a potent, selective and orally active GPR40/FFA1 agonist with an EC50 of 6 nM for human FFA1. TUG-770 shows a high selectivity for FFA1 over FFA2, FFA3, FFA4, PPARγ, other receptors, transporters, and enzymes. TUG-770 can be uesd for type 2 diabetes research[1]. TUG-770 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1402601-82-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15697.
TUG 891
TUG 891. Group: Biochemicals. Alternative Names: 4- [ (4-Fluoro-4'-methyl [1, 1'-biphenyl] -2-yl) methoxy] benzenepropanoic Acid. Grades: Highly Purified. CAS No. 1374516-07-0. Pack Sizes: 10mg. Molecular Formula: C23H21FO3, Molecular Weight: 364.41. US Biological Life Sciences.
Worldwide
TUG-891
TUG-891 is a potent and selective agonist for the long chain free fatty acid (LCFA) receptor 4 (FFA4/GPR120)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1374516-07-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100881.
Tulathromycin A
Tulathromycin A (Tulathromycin), a macrolide antibiotic, inhibits protein synthesis (IC50=0.26 μM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tulathromycin; CP 472295. CAS No. 217500-96-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15662.
Tulathromycin A
Tulathromycin A is a triamilide antibiotic used for the treatment of bovine and porcine respiratory disease. It exists as an equilibrium mixture of two isomeric forms, Tulathromycin A (90%) and B (10%). Uses: Anti-bacterial agents. Synonyms: Tulathromycin; Draxxin; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[[2,6-Dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-α-L-ribo-hexopyranosyl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one; CP 472295; Increxxa; Lydaxx; Traxovet; Tulathrin; Tulaven; Tulinovet; Tulissin. Grade: 98% by HPLC. CAS No. 217500-96-4. Molecular formula: C41H79N3O12. Mole weight: 806.08.
Tulathromycin A
Triamilide antibiotic for treatment of bovine and porcine respiratory disease. Exists as an equilibrium mixture of two isomeric forms, Tulathromycin A (90%) and B (10%). Antibacterial. Group: Biochemicals. Alternative Names: (2R, 3S, 4R, 5R, 8R, 10R, 11R, 12S, 13S, 14R)-13-[[2, 6-Dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-a-L-ribo-hexopyranosyl]oxy]-2-ethyl-3, 4, 10-trihydroxy-3, 5, 8, 10, 12, 14-hexamethyl-11-[[3, 4, 6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one; CP 472295; Draxxin. Grades: Highly Purified. CAS No. 217500-96-4. Pack Sizes: 100mg, 500mg, 1g. Molecular Formula: C41H79N3O12, Molecular Weight: 806.08. US Biological Life Sciences.
Worldwide
Tulathromycin A Impurity 1
Tulathromycin A Impurity 1. Uses: For analytical and research use. CAS No. 371193-60-1. Molecular formula: C38H73N3O12. Mole weight: 764.01. Catalog: APB371193601.
Tuliposide A
Tuliposide A is a sugar ester derived from the common tulip, consisting of D-GLC and 4-hydroxy-2-methylenebutanoyl. Tuliposide A has antibacterial activity. Synonyms: β-D-Glucopyranose, 1-(4-hydroxy-2-methylenebutanoate); 1-tuliposide A; 1-O-(4-Hydroxy-2-methylenebutanoyl)-β-D-glucopyranose; (2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl 4-hydroxy-2-methylenebutanoate. Grade: >95% by HPLC. CAS No. 19870-30-5. Molecular formula: C11H18O8. Mole weight: 278.26.
tuliposide A-converting enzyme
Isolated from the plant Tulipa gesneriana (tulip). The reaction is an intramolecular transesterification producing the lactone. The enzyme also has a weak activity with 6-tuliposide B and 6-O-benzoyl-D-glucose. Group: Enzymes. Synonyms: tuliposide-converting enzyme; 6-O-(4'-hydroxy-2'-methylenebutyryl)-D-glucose acyltransferase (lactone-forming); TCA; TCEA. Enzyme Commission Number: EC 4.2.99.22. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5268; tuliposide A-converting enzyme; EC 4.2.99.22; tuliposide-converting enzyme; 6-O-(4'-hydroxy-2'-methylenebutyryl)-D-glucose acyltransferase (lactone-forming); TCA; TCEA. Cat No: EXWM-5268.