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| Product | Description | |
|---|---|---|
| TCO-PEG3-Biotin | TCO-PEG3-Biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. TCO-PEG3-Biotin is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2098630-62-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-136050. |  |
| TCO-PEG3-maleimide | TCO-PEG3-maleimide (TCO-PEG3-NEM) is a click chemistry reagent. TCO-PEG3-maleimide efficiently binds TCO (trans-cyclooctene) moiety to thiol-containing molecules (such as antibodies, cysteine-containing peptides)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1809356-72-6. Pack Sizes: 5 mg. Product ID: HY-151696. | |
| TCO-PEG4-NHS ester | TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. TCO-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1621096-79-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141167A. | |
| TCO-PEG4-VC-PAB-MMAE | TCO-PEG4-VC-PAB-MMAE is a agent-linker conjugate for ADC. TCO-PEG4-VC-PAB-MMAE contains a cleavable ADC linker (TCO-PEG4-VC-PA) and a potent tubulin inhibitor MMAE (HY-15162)[1]. TCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2758671-45-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148057. | |
| TCO-PEG5-C2-Mal | TCO-PEG5-maleimide is a PEG linker with TCO and maleimide groups, specifically enabling tetrazine click chemistry and thiol conjugation for bioconjugation, probe design, and drug delivery. Uses: Scientific research. Category: Signaling pathways. CAS No. 2748951-17-7. Pack Sizes: 1 mg (195.09 mM * 10 μL in DMSO); 5 mg (195.09 mM * 50 μL in DMSO). Product ID: HY-164785. | |
| TCO-PEG8-NHS ester | TCO-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2353409-95-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-141169. | |
| TCO-PEG8-TFP ester | TCO-PEG8-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2353410-06-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-141173. | |
| TCO-PEG9-maleimide | TCO-PEG9-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2183440-37-9. Pack Sizes: 10 mg; 25 mg. Product ID: HY-141184. | |
| TC OT 39 | TC OT 39. Group: Biochemicals. Grades: Purified. CAS No. 479232-57-0. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| TC-P 262 | TC-P 262. Group: Biochemicals. Grades: Purified. CAS No. 873398-67-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCPOBOP | TCPOBOP. Group: Biochemicals. Grades: Purified. CAS No. 76150-91-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCPOBOP | TCPOBOP is a constitutive androstane receptor (CAR) agonist that induces robust hepatocyte proliferation and hepatomegaly without any liver injury or tissue loss[1]. TCPOBOP attenuates Fas-induced murine liver injury by altering Bcl-2 proteins[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 76150-91-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103243. | |
| TCPP-Cd(2+) | TCPP-Cd(2+). Alternative Names: cadmium(2+);hydron;4-[10,15,20-tris(4-carboxylatophenyl)porphyrin-22,24-diid-5-yl]benzoate. CAS No. 82404-76-0. Molecular formula: C48H24N4O8Cd-4·H+. Mole weight: 898.14. Purity: 95%. |  |
| TCPP-Cu(2+) | TCPP-Cu(2+). Alternative Names: Cu(II) meso-Tetra(4-carboxyphenyl)porphine. CAS No. 41699-93-8. Molecular formula: C48H28CuN4O8. Mole weight: 852.30. Purity: 95%. | |
| TCPP-Mg(2+) | TCPP-Mg(2+). Alternative Names: (SP-4-1)-Magnesate(4-), [[4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl-|EN21,|EN22,|EN23,|EN24)tetrakis[benzoato]](6-)]-, tetrahydrogen. CAS No. 212312-42-0. Molecular formula: C48H24N4O8Mg-4·H+. Mole weight: 810.04. Purity: 95%. | |
| TCPP-Mn(2+) | TCPP-Mn(2+). Alternative Names: Endo-Mn-meso-tetra(4-carboxyphenyl)porphine; hydron,manganese(2+),4-[10,15,20-tris(4-carboxylatophenyl)porphyrin-22,24-diid-5-yl]benzoate. CAS No. 73202-95-6. Molecular formula: C48H24N4O8Mn-4·H+. Mole weight: 840.67. Purity: 95%. | |
| TCPP-Ni(2+) | TCPP-Ni(2+). Alternative Names: meso-Tetra(4-carboxyphenyl)porphine-Ni(II); 5,10,15,20-Tetrakis(4-Carboxyphenyl)porphyrin-Ni(II). CAS No. 41699-92-7. Molecular formula: C48H28N4NiO8. Mole weight: 847.45. Purity: 95%. | |
| TCPP-Pd(2+) | TCPP-Pd(2+). Alternative Names: Pd(II) meso-Tetra(4-carboxyphenyl)porphine. CAS No. 94288-44-5. Molecular formula: C48H28N4O8Pd. Mole weight: 895.20. Purity: 95%. | |
| TCPP [=Tetrakis(4-carboxyphenyl)porphyrin] [Ultra-high sensitive spectrophotometric reagent for Cu, Cd] [For the simultaneous determination of metals by HPLC] | TCPP [=Tetrakis(4-carboxyphenyl)porphyrin] [Ultra-high sensitive spectrophotometric reagent for Cu, Cd] [For the simultaneous determination of metals by HPLC]. CAS No. 14609-54-2. Molecular formula: C48H30N4O8. Mole weight: 790.8g/mol. IUPAC Name: 4-[10,15,20-tris(4-carboxyphenyl)-21,23-dihydroporphyrin-5-yl]benzoic acid. SMILES: C1=CC(=CC=C1C2=C3C=CC(=C(C4=NC(=C(C5=CC=C(N5)C(=C6C=CC2=N6)C7=CC=C(C=C7)C(=O)O)C8=CC=C(C=C8)C(=O)O)C=C4)C9=CC=C(C=C9)C(=O)O)N3)C(=O)O. InChI: InChI=1S/C48H30N4O8/c53-45(54)29-9-1-25(2-10-29)41-33-17-19-35(49-33)42(26-3-11-30(12-4-26)46(55)56)37-21-23-39(51-37)44(28-7-15-32(16-8-28)48(59)60)40-24-22-38(52-40)43(36-20-18-34(41)50-36)27-5-13-31(14-6-27)47(57)58/h1-24,49,52H,(H,53,54)(H,55,56)(H,57,58)(H,59,60). | |
| TCPP-Zn(2+) | TCPP-Zn(2+). Alternative Names: Zinc(II) tetrakis(4-carboxyphenyl)porphine; Zn(II) Meso-tetra(4-carboxyphenyl) porphine. CAS No. 27647-84-3. Molecular formula: C48H24N4O8-6·Zn+2. Mole weight: 850.12. Purity: 95%. | |
| TCPZ | TCPZ. Alternative Names: 2,4,6-Tris(3-(carbazol-9-yl)phenyl)triazine. CAS No. 890148-68-2. Molecular formula: C57H36N6. Mole weight: 804.94. IUPAC Name: 9-[3-[4,6-bis(3-carbazol-9-ylphenyl)-1,3,5-triazin-2-yl]phenyl]carbazole. SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3N2C4=CC=CC(=C4)C5=NC(=NC(=N5)C6=CC(=CC=C6)N7C8=CC=CC=C8C9=CC=CC=C97)C1=CC(=CC=C1)N1C2=CC=CC=C2C2=CC=CC=C21. InChI: InChI=1S/C57H36N6/c1-7-28-49-43(22-1)44-23-2-8-29-50(44)61(49)40-19-13-16-37(34-40)55-58-56(38-17-14-20-41(35-38)62-51-30-9-3-24-45(51)46-25-4-10-31-52(46)62)60-57(59-55)39-18-15-21-42(36-39)63-53-32-11-5-26-47(53)48-27-6-12-33-54(48)63/h1-36H. | |
| TCRS-417 | TCRS-417 (T417) is a small-molecular inhibitor for PBX1. TCRS-417 can directly block PBX1-binding to DNA (IC50 = 6.58 μM), and affects PBX1 transcription. TCRS-417 is able to hammer out the stemness traits of Carboplatin (HY-17393)-resistant (CR) cells to revert to a differentiated status through tacking PBX1 signaling cascade. TCRS-417 significantly suppresses self-renewal and proliferation of cancer cells expressing high levels of PBX1. TCRS-417 can decrease the mRNA levels of FOXM1, NEK2, and E2F2 in cancer cell lines. TCRS-417 is selectively toxic against chr1q-amp myeloma and solid tumor cells[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: T417. CAS No. 2032123-28-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-153916. | |
| T.cruzi Inhibitor | T.cruzi Inhibitor is a novel inhibitor of Trypanosoma cruzi. Alternative Names: N-Benzyl-N-methyl-1-(4-(trifluoromethyl)benzyl)piperidine-3-carboxamide. CAS No. 1350920-22-7. Molecular formula: C22H25F3N2O. Mole weight: 390.45. |  |
| TCS 1105 | TCS 1105. Group: Biochemicals. Grades: Purified. CAS No. 185391-33-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCS 1205 | TCS 1205. Group: Biochemicals. Grades: Purified. CAS No. 355022-97-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCS 184 | TCS 184. Group: Biochemicals. Grades: Purified. CAS No. 1315378-71-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| TCS2002 | TCS2002 (Compound 9b) is a highly selective, orally bioavailable and potent GSK-3β inhibitor with the IC50 of 35 nM. TCS2002 shows good pharmacokinetic profiles including favorable BBB penetration. TCS2002 can be used for the research of Alzheimers disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1005201-24-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-10096. | |
| TCS 2002 | TCS 2002. Group: Biochemicals. Grades: Purified. CAS No. 1005201-24-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCS 21311 | TCS 21311. Group: Biochemicals. Grades: Purified. CAS No. 1260181-14-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCS 21311 | TCS 21311 (NIBR3049) is a potent, highly selective JAK3 inhibitor with an IC50 of 8 nM, it displays >100-fold selectivity over JAK1, JAK2 and TYK2. TCS 21311 (NIBR3049) inhibits PKCα, PKCθ, and GSK3β with IC50s of 13, 68, and 3 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NIBR3049. CAS No. 1260181-14-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108264. | |
| TCS 2210 | TCS 2210. Group: Biochemicals. Grades: Purified. CAS No. 1201916-31-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCS 2312 | TCS 2312. Group: Biochemicals. Grades: Purified. CAS No. 838823-31-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| TCS 2314 | TCS 2314. Group: Biochemicals. Grades: Purified. CAS No. 317353-73-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCS 2510 | TCS 2510. Group: Biochemicals. Grades: Purified. CAS No. 346673-06-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| TCS 2510 | TCS 2510 is a selective EP4 agonist. TCS 2510 can be used for the research of metabolic diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CAY10598. CAS No. 346673-06-1. Pack Sizes: 500 μg (13.04 mM * 100 μL in Ethanol); 1 mg (13.04 mM * 200 μL in Ethanol); 5 mg (13.04 mM * 1 mL in Ethanol); 10 mg (13.04 mM * 2 mL in Ethanol). Product ID: HY-108557. | |
| TCS 3035 | TCS 3035. Group: Biochemicals. Grades: Purified. CAS No. 871085-49-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCS 401 | TCS 401. Group: Biochemicals. Grades: Purified. CAS No. 243966-09-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| TCS 401 | TCS 401 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B). Uses: Scientific research. Category: Signaling pathways. CAS No. 243966-09-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12312. | |
| TCS 46b | TCS 46b. Group: Biochemicals. Grades: Purified. CAS No. 302799-86-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCS 5861528 | TCS 5861528. Group: Biochemicals. Grades: Purified. CAS No. 332117-28-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TC-S 7001 | TC-S 7001 is a potent and highly selective ROCK inhibitor. Its IC50 values are 0.6 and 1.1 nM for ROCK1 and ROCK2, respectively. It exhibits >200-fold selectivity over TRK and FLT3 receptors, and >900-fold selectivity over a panel of other kinases and cardiovascular relevent enzymes and receptors. It reduces blood pressure in normotensive and hypertensive rats. Alternative Names: TC-S 7001; TC S 7001; TCS 7001; TC-S-7001; TCS7001; Azaindole-1; Azaindole 1; 6-Chloro-N4-{3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl}pyrimidine-2,4-diamine;Rho Kinase Inhibitor;ROCK inhibitor;ROCK. Grades: >98 %. CAS No. 867017-68-3. Molecular formula: C18H13ClF2N6O. Mole weight: 402.79. | |
| TC-S 7003 | TC-S 7003. Group: Biochemicals. Grades: Purified. CAS No. 847950-09-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| TC-S 7005 | TC-S 7005. Group: Biochemicals. Grades: Purified. CAS No. 1082739-92-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| TC-S 7006 | TC-S 7006. Group: Biochemicals. Grades: Purified. CAS No. 871307-18-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TC-S 7009 | TC-S 7009. Group: Biochemicals. Grades: Purified. CAS No. 1422955-31-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TC-S 7010 | TC-S 7010. Group: Biochemicals. Grades: Purified. CAS No. 1158838-45-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCS HDAC6 20b | TCS HDAC6 20b. Group: Biochemicals. Grades: Purified. CAS No. 956154-63-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| TCS JNK 5a | TCS JNK 5a. Group: Biochemicals. Grades: Purified. CAS No. 312917-14-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCS JNK 5a | TCS JNK 5a is a potent JNK3 inhibitor with a pIC50 of 6.7. TCS JNK 5a also inhibits JNK2 with a pIC50 of 6.5. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JNK Inhibitor IX. CAS No. 312917-14-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15881. | |
| TCS JNK 6o | TCS JNK 6o. Group: Biochemicals. Grades: Purified. CAS No. 894804-07-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCS OX2 29 | TCS OX2 29. Group: Biochemicals. Grades: Purified. CAS No. 372523-75-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCS-OX2-29 | TCS-OX2-29 is a potent, high affinities and selective orexin-2 receptor (OX2R) antagonist with an IC50 value of 40 nM and a pKI value of 7.5. TCS-OX2-29 displays ~250-fold selectivity for OX2 over OX1[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 372523-75-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100452. | |
| TC-SP 14 | TC-SP 14. Group: Biochemicals. Grades: Purified. CAS No. 1257093-40-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCS PIM-1 1 | TCS PIM-1 1. Group: Biochemicals. Grades: Purified. CAS No. 491871-58-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCS PIM-1 1 | TCS PIM-1 1 (SC 204330) is a potent, selective and ATP-competitive Pim-1 kianse inhibitor with an IC50 of 50 nM, displays good selectivity over Pim-2 and MEK1/MEK2 (IC50s >20000 nM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SC 204330. CAS No. 491871-58-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18086. | |
| TCS PIM-1 4a | TCS PIM-1 4a. Group: Biochemicals. Grades: Purified. CAS No. 438190-29-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCS PrP Inhibitor 13 | TCS PrP Inhibitor 13. Group: Biochemicals. Grades: Purified. CAS No. 34320-83-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TCTU | TCTU. Group: Biochemicals. Alternative Names: O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N,N,N',N'-Tetramethyl-O-(6-chloro-1H-benzotriazol-1-yl)uronium tetrafluoroborate; 1-[Bis (dimethylamino) methylen]-5-chlorobenzotriazolium 3-oxide tetrafluoroborate. Grades: Highly Purified. CAS No. 330641-16-2. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C11H15BClF4N5O. US Biological Life Sciences. | Worldwide |
| TCTU | Used for peptide solid-phase synthesis. Suitable for automatic multiple peptide synthesizers. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: O-(6-Chlorobenzotriazol-1-yl)-N,N,N?,N?-tetramethyluronium tetrafluoroborate. CAS No. 330641-16-2. |  Luxembourg Bio Technologies |
| TCV-309 chloride | TCV-309 chloride is a potent and specific platelet activating factor (PAF) antagonist. TCV-309 chloride specifically inhibits PAF-induced aggregation of rabbit and human platelets, and [3H]PAF binding to rabbit platelet microsomes with IC50 values of 33 nM, 58 nM and 27 nM, respectively. TCV-309 chloride has beneficial effects in anaphylactic shock[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 121494-09-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19121A. | |
| tcY-NH2 | tcY-NH2. Group: Biochemicals. Grades: Purified. CAS No. 327177-34-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| tcY-NH2 | tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) is a potent selective PAR4 antagonist peptide. tcY-NH2 inhibits thrombin- and AY-NH2-induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology[1][2][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (trans-Cinnamoyl)-YPGKF-NH2. CAS No. 327177-34-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1263. | |
| tcY-NH2 TFA | tcY-NH2 TFA is a selective PAR4 antagonist peptide, and it inhibits thrombin- and AY-NH2-induced rat platelet aggregation. Alternative Names: N-trans-cinnamoyl-L-tyrosyl-L-prolyl-glycyl-L-lysyl-L-phenylalaninamide trifluoroacetic acid; (trans-Cinnamoyl)-YPGKF-NH2 TFA; L-Phenylalaninamide, N-[(2E)-1-oxo-3-phenyl-2-propenyl]-L-tyrosyl-L-prolylglycyl-L-lysyl-, trifluoroacetate; N-[(2E)-1-Oxo-3-phenyl-2-propen-1-yl]-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide trifluoroacetate. Grades: 99%. CAS No. 1262750-73-1. Molecular formula: C42H50F3N7O9. Mole weight: 853.88. | |
| tcY-NH2 TFA | tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) TFA is a potent selective PAR4 antagonist peptide. tcY-NH2 TFA inhibits thrombin- and AY-NH2-induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology[1][2][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (trans-Cinnamoyl)-YPGKF-NH2 TFA. CAS No. 1262750-73-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1263A. | |
| TD034 | TD034 is a selective, reversible and noncovalent HDAC11 inhibitor with an IC50 of 5.1 nM and a Ki of 1.5 nM. TD034 does not inhibit other HDACs or sirtuins. TD034 inhibits the defatty acylation of SHMT2 (HDAC11 substrate). TD034 decreases the YAP1 level via HDAC11 inhibition. TD034 can be used for the study of lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3030718-42-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-176542. | |
| TD1092 | TD1092 is a pan-IAP degrader, degrades cIAP1, cIAP2, and XIAP. TD1092 activates Caspase 3/7, and promotes cancer cells apoptosis via IAP degradation. TD1092 inhibits TNFα mediated NF-κB pathway and reduces the phosphorylation of IKK, IkBα, p65, and p38. TD1092 can act as PROTAC, and is used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3037417-26-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151966. | |
| TD-165 | TD-165 is a PROTAC-based cereblon (CRBN) degrader. TD-165 comprises a?cereblon (CRBN)?ligand binding group, a linker and an?von Hippel-Landau (VHL)?binding group[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2305936-56-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130714. | |
| TD-198946 | TD-198946, a thienoindazole derivative, is a potent chondrogenic agent. Uses: Scientific research. Category: Signaling pathways. CAS No. 364762-86-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15642. | |
| TD-428 | TD-428 is a PROTAC connected by ligands for Cereblon and BRD4. TD-428 is a highly specific BRD4 degrader with a DC50 of 0.32 nM[1]. TD-428 is a BET PROTAC, which comprises TD-106 (a CRBN ligand) linked to JQ1 (a BET inhibitor). TD-428 efficiently induce BET protein degradation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2334525-50-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114407. | |
| TD52 | TD52, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 has less p-EGFR inhibition and has potent anti-cancer activity[1]. TD52 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1798328-24-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135699. | |
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