A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Potent 17beta-hydroxysteroid dehydrogenase type 3 (17beta-HSD3) inhibitor (IC50 values are 6 and 40nm at human and mouse 17beta-HSD3 respectively). Displays no activity at 17beta-HSD1, 17beta-HSD2, ERalpha, androgen receptors or glucocorticoid receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 330203-01-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
TC-I 15
TC-I 15 (TC-I-15) is a type of allosteric collagen-binding integrin ?2?1 inhibitor, and it also inhibits ?1?1 and ?11?1. TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition. TC-I 15 prevents the formation of a pre-metastatic microenvironment by inhibiting the uptake of cancer-associated fibroblast (CAF) extracellular vesicles (EVs) by lung fibroblasts, which reduces the metastasis of salivary gland adenocystic carcinoma (SACC) to the lungs in mouse models, [1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 916734-43-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107588.
TC-I 2000
TC-I 2000. Group: Biochemicals. Grades: Purified. CAS No. 1159996-20-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TC-I 2014
TC-I 2014. Group: Biochemicals. Grades: Purified. CAS No. 1221349-53-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TCID
TCID. Group: Biochemicals. Grades: Purified. CAS No. 30675-13-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
TCID (4,5,6,7-Tetrachloroindan-1,3-dione) is a potent and selective neuronal ubiquitin C-terminal hydrolase (UCH-L3) inhibitor with an IC 50 of 0.6 μM [1]. TCID diminishes glycine transporter GlyT2 ubiquitination in brainstem and spinal cord primary neurons [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4,5,6,7-Tetrachloroindan-1,3-dione. CAS No. 30675-13-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-18638.
TCL053
TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle[1][2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2361162-70-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147332.
TC LPA5 4
TC LPA5 4 is a LPA 5 (GPR92) -specific non-lipid antagonist. TC LPA5 4 inhibits LPA-induced aggregation of isolated human platelet (LPA 5 -RH7777 cell line) with an IC 50 of 800 nM. TC LPA5 4 displays selectivity for LPA 5 over 80 other screened agent targets [1]. TC LPA5 4 inhibits cell proliferation and migration of thyroid cancer cells [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1393814-38-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107615.
TC LPA5 4
TC LPA5 4. Group: Biochemicals. Grades: Purified. CAS No. 1393814-38-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TCLP Metals - Ash 1
certified reference material, pkg of 225 g. Group: Application areas.
TCMCB07, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 plays an important role in cachexia [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Mifomelatide. CAS No. 1456699-27-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5971.
TC-MCH 7c
TC-MCH 7c. Group: Biochemicals. Grades: Purified. CAS No. 864756-35-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
TCMDC-135051
TCMDC-135051 is a highly selective and potent protein kinase Pf CLK3 inhibitor with low off-target toxicity. TCMDC-135051 prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 has antiparasiticidal activity (EC 50 =320 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2413716-15-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126323.
TCMDC-135051 hydrochloride
TCMDC-135051 hydrochloride is a highly selective and potent protein kinase Pf CLK3 inhibitor with low off-target toxicity. TCMDC-135051 hydrochloride prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 hydrochloride has antiparasiticidal activity (EC 50 =320 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2705545-47-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-126323B.
TC Mps1 12
TC Mps1 12. Group: Biochemicals. Grades: Purified. CAS No. 1206170-62-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TCMTB
TCMTB is one of the so-called emerging contaminants (EC). TCMTB is also an antifouling agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 21564-17-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101425.
TC-N 1752
TC-N 1752 is a potent and orally active inhibitor of Nav1.7, with IC50s of 0.17 ?M, 0.3 ?M, 0.4 ?M, 1.1 ?M and 2.2 ?M at hNav1.7, hNav1.3, hNav1.4, hNaV1.5 and rNav1.8, respectively. TC-N 1752 also inhibits tetrodotoxin-sensitive sodium channels. TC-N 1752 shows analgesic efficacy in the Formalin model of pain[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1211866-85-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107405.
TC-N 1752
TC-N 1752. Group: Biochemicals. Grades: Purified. CAS No. 1211866-85-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TCN 201
TCN 201. Group: Biochemicals. Grades: Purified. CAS No. 852918-02-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
A negative allosteric modulator selective for NR2A containingnMDA receptors (pIC50 = 6.8 and <4.3uM for NR2A and NR2B, respectively). No effect on NR2B-containingnMDA receptors with concentrations less than 50 mM. Inhibition on NR2A containingnMDA receptors is glycine (or D-serine)-binding, but not glutamate-binding, dependent. Group: Biochemicals. Grades: Highly Purified. CAS No. 852918-02-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
TCN 213
TCN 213. Group: Biochemicals. Alternative Names: N-(Cyclohexylmethyl)-2-[[5-[(phenylmethyl)amino]-1,3,4-thiadiazol-2-yl]thio]-acetamide. Grades: Highly Purified. CAS No. 556803-08-8. Pack Sizes: 10mg. Molecular Formula: C18H24N4OS2, Molecular Weight: 376.54. US Biological Life Sciences.
Worldwide
TC-N 22A
TC-N 22A. Group: Biochemicals. Grades: Purified. CAS No. 1314140-00-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TCN 237 dihydrochloride
TCN 237 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 700878-19-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
TCN 238
TCN 238. Group: Biochemicals. Grades: Purified. CAS No. 125404-04-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TC NTR1 17
TC NTR1 17. Group: Biochemicals. Grades: Purified. CAS No. 1146757-96-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TCNT Type 1- Carbon Nanotubes Thin Walled
TCNT Type 1- Carbon Nanotubes Thin Walled. Group: Nanotubes. CAS No. 308068-56-6.
TC-O 9311
TC-O 9311. Group: Biochemicals. Grades: Purified. CAS No. 444932-31-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TCO-NHS ester
TCO-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs [1]. TCO-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1191901-33-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-141165.
TCO-PEG3-Biotin
TCO-PEG3-Biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. TCO-PEG3-Biotin is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg. Product ID: HY-136050.
A FITC probe functionalized with a TCO moiety for tetrazine-TCO ligation and a PEG3 spacer. Uses: For industrial and laboratory use. Product Category: Other Fluorescent Dyes. Appearance: Orange solid. Molecular formula: C38H43N3O10S. Mole weight: 733.83 g/mol. Purity: 0.95. Product ID: DYE-FLU-0102. Alfa Chemistry ISO 9001:2015 Certified.
TCO-PEG3-maleimide
TCO-PEG3-maleimide (TCO-PEG3-NEM) is a click chemistry reagent. TCO-PEG3-maleimide efficiently binds TCO (trans-cyclooctene) moiety to thiol-containing molecules (such as antibodies, cysteine-containing peptides) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1809356-72-6. Pack Sizes: 5 mg. Product ID: HY-151696.
TCO-PEG4-biotin
TCO-PEG4-biotin is a polyethylene glycol (PEG)-based PROTAC linker. TCO-PEG4-biotin can be used in the synthesis of a series of PROTACs. Grade: 95%. CAS No. 2183440-30-2. Molecular formula: C29H50N4O8S. Mole weight: 614.79.
TCO-PEG4-NHS ester
TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. TCO-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1621096-79-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141167A.
TCO-PEG4-VC-PAB-MMAE
TCO-PEG4-VC-PAB-MMAE is a agent-linker conjugate for ADC. TCO-PEG4-VC-PAB-MMAE contains a cleavable ADC linker (TCO-PEG4-VC-PA) and a potent tubulin inhibitor MMAE (HY-15162)[1]. TCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2758671-45-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148057.
TC OT 39
TC OT 39. Group: Biochemicals. Grades: Purified. CAS No. 479232-57-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
TC-P 262
TC-P 262. Group: Biochemicals. Grades: Purified. CAS No. 873398-67-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Tcpobop
TCPOBOP is a constitutive androstane receptor (CAR) agonist that induces robust hepatocyte proliferation and hepatomegaly without any liver injury or tissue loss. TCPOBOP attenuates Fas-induced murine liver injury by altering Bcl-2 proteins. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 76150-91-9. Molecular formula: C16H8Cl4N2O2. Mole weight: 402.06. Purity: 0.9807. Product ID: ACM76150919. Alfa Chemistry ISO 9001:2015 Certified.
TCPP-Mn(2+). Group: Porphyrin-metallo-porphyrines. Alternative Names: Endo-Mn-meso-tetra(4-carboxyphenyl)porphine; hydron,manganese(2+),4-[10,15,20-tris(4-carboxylatophenyl)porphyrin-22,24-diid-5-yl]benzoate. CAS No. 73202-95-6. Molecular formula: 840.67. Mole weight: C48H24N4O8Mn-4·H+. 95%.
TCPP-Ni(2+)
TCPP-Ni(2+). Group: Porphyrin-metallo-porphyrines. Alternative Names: meso-Tetra(4-carboxyphenyl)porphine-Ni(II); 5,10,15,20-Tetrakis(4-Carboxyphenyl)porphyrin-Ni(II). CAS No. 41699-92-7. Molecular formula: 847.45. Mole weight: C48H28N4NiO8. 95%.
TCPP-Pd(2+)
TCPP-Pd(2+). Group: Porphyrin-metallo-porphyrines. Alternative Names: Pd(II) meso-Tetra(4-carboxyphenyl)porphine. CAS No. 94288-44-5. Molecular formula: 895.20. Mole weight: C48H28N4O8Pd. 95%.
TCPP [=Tetrakis(4-carboxyphenyl)porphyrin] [Ultra-high sensitive spectrophotometric reagent for Cu, Cd] [For the simultaneous determination of metals by HPLC]