A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
TBAJ-587, a potent anti-tuberculosis agent, inhibits M.tb strain H37Rv growth with MIC90s of 0.006 and <0.02 μg/mL in MABA and LORA assay, respectively. TBAJ-587 inhibits hERG channel minimally, attenuates inhibition of the cardiac potassium channel protein coded by the hERG, which is important for cardiac repolarization[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2252316-16-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111747.
TBB
TBB is a cell-permeable and ATP-competitive CK2 inhibitor with an IC50 of 0.15 μM for rat liver CK2. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 231634; Casein Kinase II Inhibitor I. CAS No. 17374-26-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14394.
TBB
TBB. Group: Biochemicals. Grades: Purified. CAS No. 17374-26-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TBE buffer solution (10X)
1lt Pack Size. Group: Biochemicals, Buffers. Formula: N/A. Prepack ID 10590369-1lt. See USA prepack pricing.
TBE buffer solution (10X)
5lt Pack Size. Group: Biochemicals, Buffers. Formula: N/A. Prepack ID 10590369-5lt. See USA prepack pricing.
TBHQ
TBHQ (tert-Butylhydroquinone) is a widely used Nrf2 activator, protects against Doxorubicin (DOX)-induced cardiotoxicity through activation of Nrf2[1]. TBHQ (tert-Butylhydroquinone) is also an ERK activator; rescues Dehydrocorydaline (DHC)-induced cell proliferation inhibitionin melanoma[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: tert-Butylhydroquinone. CAS No. 1948-33-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-100489.
TBI-166
TBI-166, a riminophenazine analogue, is an orally active anti-tuberculosis agent with fewer adverse reactions than the lead riminophenazine compound, Clofazimine (HY-B1046) [1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1353734-12-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-148564.
TBI-223
TBI-223 is an orally active oxazolidinone antibiotic and an antimicrobial. TBI-223 shows activity against Mycobacterium tuberculosis (Mtb). TBI-223 exhibits an IC50 of 68 μg/mL for inhibiting mitochondrial protein synthesis (MPS) in HepG2 cells. TBI-223 is effective in three mouse models (bloodstream infection, skin infection, and bone infection) of methicillin-resistant staphylococcus aureus infection. TBI-223 can be used for the study of tuberculosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2071265-08-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139398.
tBID
tBID is a selective inhibitor of homeodomain-interacting protein kinase 2 (HIPK2) with an IC50 of 0.33 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1639895-85-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100464.
TBK1/IKKε-IN-2
TBK1/IKKε-IN-2 is a dual TBK1 and IKKε inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 1292310-49-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12453.
TBK1/IKKε-IN-4
TBK1/IKKε-IN-4 is a 6-aminopyrazolopyrimidine derivative and a potent, selective TBK1 and IKKε inhibitor with IC50 values of 13 nM and 59 nM, respectively. TBK1/IKKε-IN-4 shows 100- to 1000-fold less activity against other protein kinases including PDK1, PI3K family members and mTOR[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1381930-17-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124652.
TBK1/IKKε-IN-5
TBK1/IKKε-IN-5 (compound 1) is an orally active TBK1 and IKKε dual inhibitor, with IC50 values of 1 and 5.6 nM, respectively. TBK1/IKKε-IN-5 enhances the blockade response to PD-1 and induces immune memory in rats when combines with anti-PD-L1. TBK1/IKKε-IN-5 can be used in cancer research, especially in tumour immunity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1893397-65-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128679.
TBK1-IN-1
TBK1-IN-1 is a potent and selective TANK binding kinase 1 (TBK1) inhibitor with an IC50 value of 22.4 nM. TBK1-IN-1 inhibits TBK1 downstream target genes cxcl10 and ifnβ expression. TBK1-IN-1 has anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3041973-64-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-152237.
TBK1/NAK Antibody [K6D9]
NAK/TBK1,TBK1,TBK1/NAK. Group: Antibodies. Alternative Names: NAK/TBK1,TBK1. Pack Sizes: 20uL. Product ID: F0525. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
A novel heterobifunctional linker for facile access to bioconjugates. Group: Biochemicals. Alternative Names: 2- [ [ [ (1, 1-Dimethylethoxy) carbonyl] amino] oxy] acetic Acid 2,5-Dioxo-1-pyrrolidinyl Ester; [2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethoxy]carbamic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 80366-85-4. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
t-Boc-Aminooxy-PEG4-NHS ester
t-Boc-Aminooxy-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2401831-99-8. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-140417.
Tert-butyl 2-(2-aminoethoxy)ethyl carbamate (CAS# 127828-22-2) is a useful research chemical. Synonyms: tert-Butyl (2-(2-aminoethoxy)ethyl)carbamate; N-Boc-2-(2-aminoethoxy)ethylamine; Amino-PEG2-NH-Boc; 5-(tert-butyloxycarbonylamino)-3-oxa-pentyl amine; N-t-butoxycarbonyl-3-oxa-1,5-pentanediamine; AmbotzPEG1067; 1-t-butoxycarbonylamino-3-oxa-pentan-5-amine; t-Boc-N-amido-PEG1-Amine; BocNH-PEG1-CH2CH2NH2. Grade: 97 % (NMR). CAS No. 127828-22-2. Molecular formula: C9H20N2O3. Mole weight: 204.27.
t-Boc-N-amido-PEG2-acetic acid
Boc-AEEA-OH is a cleavable ADC linker used in the synthesis of ADCs. Synonyms: 2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid; t-Boc-N-amido-PEG2-CH2CO2H; Boc-NH-PEG2-CH2COOH; boc-8-amino-3,6-dioxaoctanoic acid. Grade: 98%. CAS No. 108466-89-3. Molecular formula: C11H21NO6. Mole weight: 263.29.
Boc-NH-PEG2-C2-NH2 is a PROTAC linker, which refers to the alkyl/ether composition. Boc-NH-PEG2-C2-NH2 can be used in the synthesis of a series of PROTACs. Boc-NH-PEG2-C2-NH2 is a PEG derivative containing an amino group and Boc-protected amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates and PROTACs. Synonyms: NHBoc-PEG2-amine; Boc-NH-PEG2-C2-NH2; BocNH-PEG2-CH2CH2NH2; N-(tert-Butoxycarbonyl)-3,6-dioxa-1,8-octanediaminetert-Butyl (2-(2-(2-aminoethoxy)ethoxy)ethyl)carbamate; Boc-1-amino-3,6-dioxa-8-octanediamine; N-Boc-2-[2-(2-amino-ethoxy)-ethoxy]-ethylamine; N-Boc-2,2'-(ethylenedioxy)diethylamine; N-Boc-3,6-dioxaoctane-1,8-diamine; Boc-N-amido-PEG2-Amine; N-Boc-3,6-dioxa-1,8-octanediamine; 1-(t-Butyloxycarbonyl-amino)-3,6-dioxa-8-octaneamine. Grade: ≥95%. CAS No. 153086-78-3. Molecular formula: C11H24N2O4. Mole weight: 248.32.
t-Boc-N-amido-PEG2-azide
Boc-N-Amido-PEG2-C2-azide is a polyethylene glycol (PEG)-based PROTAC linker. Boc-N-Amido-PEG2-C2-azide can be used in the synthesis of a series of PROTACs. Synonyms: tert-butyl {2-[2-(2-azidoethoxy)ethoxy]ethyl}carbamate; Boc-NH-PEG(2)-N3. Grade: ≥ 98% (HPLC). CAS No. 950683-55-3. Molecular formula: C11H22N4O4. Mole weight: 274.30.
CD Bioparticles provides tBoc-NH-PEG-NH2, Heterobifunctional Linear PEGs with a PEG molecular weight of 1,000 Da for drug delivery. Group: Heterobifunctional linear pegs.
TBPB
TBPB. Group: Biochemicals. Alternative Names: 1, 3-Dihydro-1-[1'-[ (2-methylphenyl) methyl][1, 4'-bipiperidin]-4-yl]-2H-benzimidazol-2-one. Grades: Highly Purified. CAS No. 634616-95-8. Pack Sizes: 10mg. Molecular Formula: C25H32N4O, Molecular Weight: 404.55. US Biological Life Sciences.
Worldwide
TBPe
Electron transport and hole blocking material in organic light emitting diodes (OLED). Alternative Names: 2,5,8,11-Tetrakis(1,1-dimethylethyl)perylene,2,5,8,11-Tetra-tert-butylperylene,TBP. CAS No. 80663-92-9. Molecular formula: C36H44. Mole weight: 476.73. Purity: 95%+. IUPAC Name: 2,5,8,11-tetratert-butylperylene. SMILES: CC(C)(C)C1=CC2=C3C(=C1)C=C(C=C3C4=CC(=CC5=CC(=CC2=C54)C(C)(C)C)C(C)(C)C)C(C)(C)C. InChI: InChI=1S/C36H44/c1-33(2,3)23-13-21-14-24(34(4,5)6)19-29-30-20-26(36(10,11)12)16-22-15-25(35(7,8)9)18-28(32(22)30)27(17-23)31(21)29/h13-20H,1-12H3.
TBTU
TBTU. Group: Biochemicals. Alternative Names: N,N,N',N'-Tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborate; O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate. Grades: Highly Purified. CAS No. 125700-67-6. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C11H16N5O·BF4. US Biological Life Sciences.
Worldwide
TBTU
Popular in situ activation reagents in solid and solution phase peptide synthesis. In addition to having high reactivity, TBTU have also been shown to limit enantiomerization during fragment condensation. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: O-(Benzotriazol-1-yl)-N,N,N?,N?-tetramethyluronium tetrafluoroborate. CAS No. 125700-67-6.
100g Pack Size. Group: Building Blocks, Organics, Peptide Reagents. Formula: C11H16BF4N5O. CAS No. 125700-67-6. Prepack ID 39093565-100g. Molecular Weight 321.0822528. See USA prepack pricing.
1kg Pack Size. Group: Building Blocks, Organics, Peptide Reagents. Formula: C11H16BF4N5O. CAS No. 125700-67-6. Prepack ID 39093565-1kg. Molecular Weight 321.0822528. See USA prepack pricing.
tBuBrettPhos Pd G3
tBuBrettPhos Pd G3. Alternative Names: Ditert-butyl-[3,6-dimethoxy-2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane;methanesulfonic acid;palladium;2-phenylaniline. CAS No. 1536473-72-9. Purity: 98%. Product ID: ACM1536473729. Molecular formula: C44H63NO5PPdS. Mole weight: 855.4. Canonical SMILES: CC(C)C1=CC(=C(C(=C1)C(C)C)C2=C(C=CC(=C2P(C(C)(C)C)C(C)(C)C)OC)OC)C(C)C.CS(=O)(=O)O.C1=CC=C([C-]=C1)C2=CC=CC=C2N.[Pd]. Alfa Chemistry - ISO 9001:32057 Certified.
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu
A 18-carbon fatty acid side chain of semaglutide. The affinity of the semaglutide side chain for albumin was enhanced 5-6 times. Semaglutide is a glucagon-like peptide-1 (GLP-1) analog with significant hypoglycemic efficacy. Synonyms: Semaglutide Side Chain; Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OHu; (S)-22-(Tert-butoxycarbonyl)-10,19,24-trioxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontane-1,41-dioic acid; (S)-22-(tert-butoxycarbonyl)-43,43-dimethyl-10,19,24,41-tetraoxo-3,6,12,15,42-pentaoxa-9,18,23-triazatetratetracontanoic acid. Grade: ≥98%. CAS No. 1118767-16-0. Molecular formula: C43H79N3O13. Mole weight: 846.11.
t-Butoxycarbonylamide
t-Butoxycarbonylamide can be used in palladium-catalyzed synthesis of N-Boc-protected anilines. Synonyms: Boc-NH2; tert-Butyl carbamate; T-butt-Butyl carbamate; Carbamic acid tert-butyl ester; Boc amine; Boc-amide; Carbamic acid, 1,1-dimethylethyl ester; MFCD00007962; N-boc amine; EINECS 224-209-3; 1,1-dimethylethyl carbamate; KSC489S5L; N-t-Butoxycarbonyl-amide. Grade: ≥ 98 %. CAS No. 4248-19-5. Molecular formula: C5H11NO2. Mole weight: 117.15.
t-Butyl Hydroperoxide 70%. CAS No. 75-91-2. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.