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| Product | Description | |
|---|---|---|
| TAS4464 | TAS4464 is a potent and selective NEDD8 activating enzyme (NAE) inhibitor with IC50 of 0.955 nM. It selectively inhibits NAE relative to the other E1s UAE and SAE. TAS4464 treatment inhibits cullin neddylation and subsequently induces the accumulation of CRL substrates such as CDT1, p27, and phosphorylated IkBa in human cancer cell lines. Alternative Names: 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-[5-[(aminosulfonyl)amino]-5-deoxy-beta-D-ribofuranosyl]-5-[2-(2-ethoxy-6-fluorophenyl)ethynyl]-. CAS No. 1848959-10-3. Molecular formula: C21H23FN6O6S. Mole weight: 506.5. |  |
| Taselisib | Taselisib (GDC-0032) is a potent PI3K inhibitor targets PIK3CA mutations, with Kis of 0.12 nM, 0.29 nM, 0.97 nM, and 9.1 nM for PI3Kδ, PI3Kα, PI3Kγ and PI3Kβ, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GDC-0032; RG-7604. CAS No. 1282512-48-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13898. |  |
| TAS-F | TAS-F. Alternative Names: TAS-F; TRIS(DIMETHYLAMINO)SULFONIUM DIFLUOROTRIMETHYLSILICATE; TRIS(DIMETHYLAMINO)SULFUR TRIMETHYLSILY DIFLUORIDE; TRIS(DIMETHYLAMINO)SULFUR (TRIMETHYLSILYL)DIFLUORIDE; TRIS(DIMETHYLAMINO)(TRIMETHYLSILYL)SULFUR DIFLUORIDE; TRIS(DIMETHYLAMINO)(TRIMETHYLSILYL)S. CAS No. 59218-87-0. Molecular formula: C9H27F2N3SSi. Mole weight: 275.48. | |
| Tasimelteon | Tasimelteon (trade name Hetlioz) is a drug approved by the FDA solely for the treatment of non-24-hour sleep-wake disorder (often designated as N24HSWD) in totally blind adults. It is a selective agonist for the melatonin receptors MT1 and MT2 in the suprachiasmatic nucleus of the brain, similar to other members of the melatonin receptor agonist class of which ramelteon (2005) and agomelatine (2009) were the first approved. Uses: Tasimelteon is a novel drug, used in the treatment of non-24 hour sleep-wake disorder. it helps to correct the circadian rhythm disorder often seen in patients who are visually impaired. Alternative Names: BMS-214,778; BMS-214778; BMS214778; BMS 214778. VEC-162; VEC162; VEC 162. Trade name: Hetlioz. Grades: ≥ 99.0%. CAS No. 609799-22-6. Molecular formula: C15H19NO2. Mole weight: 245.32. | |
| Tasimelteon | Tasimelteon (BMS-214778) is an orally active and selective dual melatonin receptor agonist (DMRA). Tasimelteon has 2.1-4.4 times greater affinity for the MT2 receptor than for the MT1 receptor. Tasimelteon is a circadian regulator and has the potential for Non-24-Hour Sleep-Wake Disorder (Non-24)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-214778; VEC-162. CAS No. 609799-22-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-14803. | |
| TASIN-1 | TASIN-1 is a selective inhibitor of truncated APCTR (adenomatous polyposis coli gene) that exerts cytotoxic effects by inhibiting cholesterol biosynthesis. TASIN-1 specifically targets colorectal cancer (CRC) cells carrying APC truncated mutations, while having no significant toxicity to wild-type APC cells. TASIN-1 exerts cytotoxic effects by targeting Emopamil binding protein (EBP) to inhibit cholesterol biosynthesis, triggering endoplasmic reticulum (ER) stress, reactive oxygen species (ROS) generation, and JNK-mediated apoptosis, and inhibiting Akt survival signaling. TASIN-1 can be used to prevent and intervene in APC mutant colorectal cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 792927-06-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116572A. | |
| TASIN-30 | TASIN-30 is a selective EBP inhibitor with an EC50 of 0.097 μM. TASIN-30 blocks the production of 7-dehydrocholesterol (7-DHC) and downstream cholesterol biosynthesis processes. TASIN-30 depletes downstream sterols, disrupts the integrity of lipid rafts in tumor cells, accelerates intracellular cholesterol consumption, and inhibits tumor cell proliferation. TASIN-30 induces ferroptosis and apoptosis by reducing 7-DHC levels and increasing phospholipid peroxidation. TASIN-30 achieves tumor suppression in nude mice with osteosarcoma. TASIN-30 can be used in cancer-related research such as colorectal cancer and osteosarcoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1678515-93-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164561. | |
| Tasisulam | Tasisulam is a anticancer agent and induces apoptosis via the intrinsic pathway, resulting in cytochrome c release and caspase-dependent cell death. Tasisulam inhibits mitotic progression and induces vascular normalization[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY 573636. CAS No. 519055-62-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14804. | |
| Tasosartan | Tasosartan is a long-acting angiotensin II (AngII) receptor antagonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: WAY-ANA 756. CAS No. 145733-36-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-A0250. | |
| Taspine | Taspine is an alkaloid isolated from Radix et Rhizoma Leonticis. It shows various pharmaceutical properties: bacteriostatic, wound healing, cytotoxicity, immunosuppression, acetilcholinesterase inhibition, and inhibition of the activity of tumor angiogenesis. Used as human acid beta-glucosidase inhibitor and for the treatment of Gaucher disease. Group: Biochemicals. Alternative Names: 1-[2-(Dimethylamino)ethyl]-3,8-dimethoxy-[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione; Thaspine; NSC 688259; Taspin. Grades: Highly Purified. CAS No. 602-07-3. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Taspine | Taspine, a kind of alkaloid compound, has been found to be active as immunosuppressive agent, acetilcholinesterase inhibitor as well as tumor angiogenesis inhibitor. Alternative Names: 1-[2-(Dimethylamino)ethyl]-3,8-dimethoxy-[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione; Thaspine; NSC 688259. Grades: > 95%. CAS No. 602-07-3. Molecular formula: C20H19NO6. Mole weight: 369.38. | |
| Taspoglutide | Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist (EC50 = 0.06 nM) under investigation for treatment of type 2 diabetes. Alternative Names: (N-((N-(L-histidyl)-2-aminoisobutyryl)-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-glycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysyl)-2-aminoisobutyryl)-L-argininamide; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Aib-Arg-NH2. CAS No. 275371-94-3. Molecular formula: C152H232N40O45. Mole weight: 3339.71. | |
| Taspoglutide | Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist developed for treatment of type 2 diabetes, with an EC50 value of 0.06 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ITM077; R1583; BIM51077. CAS No. 275371-94-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0165. | |
| Tasquinimod | Tasquinimod is an oral antiangiogenic agent, which has the potential for castration-resistant prostate cancer treatment. Tasquinimod binds to the regulatory Zn2+ binding domain of HDAC4 with Kd of 10-30 nM. Tasquinimod also is a S100A9 inhibitor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABR-215050. CAS No. 254964-60-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10528. | |
| TAT | TAT (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologous proteins[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAT(47-57); HIV-1 TAT protein (47-57). CAS No. 191936-91-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0281. | |
| TAT | TAT is a TAT peptide encoded by HIV-1 virus, which can increase the yields and solubility of heterologous proteins. Alternative Names: Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2; (2S)-2-[(2S,8S,11S,14S,17S,20S)-2-Amino-11,14-bis(4-aminobutyl)-21-{[(1S)-1-{N-[(2S)-5-carbamimidamido-1-{[(2S)-5-carbamimidamido-1-{[(2S)-5-carbamimidamido-1-hydroxy-1-imino-2-pentanyl]imino}-1-hydroxy-2-pentanyl]imino}-1-hydroxy-2-pentanyl]imidic acid}-3-imidicacidpropyl]imino}-8,17,20-tris(3-carbamimidamidopropyl)-3,6,9,12,15,18,21-heptahydroxy-1-(4-hydroxyphenyl)-4,7,10,13,16,19-hexaazahenicosa-3,6,9,12,15,18-hexaen-yl]-N1-[(2S)-5-carbamimidamido-1-{[(2S)-5-carbamimidamido-1-{[(2S)-5-carbamimidamido-1-hydroxy-1-imino-2-pentanyl]imino}-1-hydroxy-2-pentanyl]imino}-1-hydroxy-2-pentanyl]pentanediimidic acid; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-argininamide. Grades: ≥95% by HPLC. CAS No. 697226-52-1. Molecular formula: C64H119N33O13. Mole weight: 1558.85. | |
| TAT 14 | TAT 14 is an Nrf2 activator and inhibits Nrf2/Keap1 interaction with neuroprotective activity. TAT 14 has been shown to induce upregulation of Nrf2 pathway downstream gene expression including heme-oxygenase 1 and suppress LPS-induced TNF-α expression in THP-1 cells. Alternative Names: TAT14; TAT-14; H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Leu-Gln-Leu-Asp-Glu-Glu-Thr-Gly-Glu-Phe-Leu-Pro-Ile-Gln-OH; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-leucyl-L-glutaminyl-L-leucyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alpha-glutamyl-L-threonyl-glycyl-L-alpha-glutamyl-L-phenylalanyl-L-leucyl-L-prolyl-L-isoleucyl-L-glutamine; TAT 14 Peptide (Nrf2 Activator III). Grades: ≥95%. CAS No. 1362661-34-4. Molecular formula: C137H230N48O39. Mole weight: 3173.59. | |
| TAT 14 | TAT 14. Group: Biochemicals. Grades: Purified. CAS No. 1362661-34-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| TAT 2-4 | TAT 2-4 is a peptide derived from the HIV-1 transactivator of transcription (Tat) protein. Alternative Names: Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly; L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginylglycyl-L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginylglycine. Grades: ≥95%. CAS No. 1159916-66-1. Molecular formula: C132H240N66O29. Mole weight: 3215.74. | |
| TAT (47-57), FAM-labeled | It is a fluorescent (FAM) labeled TAT peptide, Abs/Em=494/521 nm. TAT is the most characteristic fragment of HIV trans-activator protein (TAT). The arginine-rich TAT peptide penetrates the plasma membrane directly rather than through endocytosis. Alternative Names: FAM-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-OH; N-[(3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-5-yl)carbonyl]-L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginine; 5-FAM-HIV-1 Tat Protein (47-57). Grades: ≥95%. CAS No. 1676104-81-6. Molecular formula: C85H128N32O20. Mole weight: 1918.16. | |
| TAT (47-57) GGG-Cys(Npys) | It corresponds to the protein transduction domain of the TAT protein and is synthesized with an activated cysteine residue C(Npys), where Npys is 3-Nitro-2-pyridinesulfenyl group and is used for activating S of cysteine and for rapid reaction when a thiol group is introduced. The N-terminus is rendered free for applications requiring certain conjugation reactions with a free N-terminal end, and a linker GGG is placed at the C-terminal end, and the peptide has been synthesized with the C(Npys) group. This kind of modification has been used to render this peptide as a cell penetrating and carrier peptide applicable in conjugation studies. Alternative Names: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Gly-Cys(Npys)-NH2. Grades: ≥95%. Molecular formula: C78H135N39O19S2. Mole weight: 1987.29. | |
| TAT (47-57), TAMRA-labeled | It is a fluorescent (TAMRA)-labeled TAT peptide, Abs/Em=541/568 nm. TAT is the most characteristic fragment of HIV trans-activator protein (TAT). The arginine-rich TAT peptide penetrates the plasma membrane directly rather than through endocytosis. Alternative Names: TAMRA-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-OH. Grades: ≥95%. | |
| TAT 48-57 | It is a cell-permeable peptide, derived from HIV-1 transactivator of transcription (Tat) protein residues 48-57. Alternative Names: H-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-OH; glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginine; Tat protein (48-57); TAT (48-57). Grades: ≥95%. CAS No. 253141-50-3. Molecular formula: C55H109N31O12. Mole weight: 1396.65. | |
| TAT (48-57) TFA | It is a cell-permeable peptide, derived from HIV-1 transactivator of transcription (Tat) protein residues 48-57. Alternative Names: Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg.TFA; glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginine; Tat protein (48-57). Grades: >98%. Molecular formula: C55H109N31O12.C2HF3O2. Mole weight: 1510.67. | |
| TATA (1,3,5-Triacryloylhexahydro-1,3,5-triazine) (CAS 959-52-4) | TATA (1,3,5-Triacryloylhexahydro-1,3,5-triazine) (CAS 959-52-4). CAS No. 959-52-4. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  |
| TAT-amide | TAT-amide is a cell penetrating peptide. Cell-penetrating peptides (CPPs) are short amino acid sequences able to enter different cells[1][2]. Uses: Scientific research. Category: Peptides. CAS No. 697226-52-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2193. | |
| Tat-beclin 1 | Tat-beclin 1, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer of autophagy and interacts with negative regulator of autophagy, GAPR-1 (GLIPR2). Tat-beclin 1 decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens (including HIV-1) in vitro, and reduces mortality in mice infected with chikungunya (CHIKV) or West Nile virus (WNV)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1423821-88-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P2260. | |
| Tat-Beclin-1 | Beclin-1 peptide is the HIV-1 Nef binding portion of full-length human Beclin-1 protein (amino acids 267-299). Beclin-1 protein is an autophagy inducing agent that triggers cell adaptation, survival, or death. When combined with the cell-permeable peptide, it can successfully enter cells and induce autophagy. Alternative Names: Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Thr-Asn-Val-Phe-Asn-Ala-Thr-Phe-Glu-Ile-Trp-His-Asp-Gly-Glu-Phe-Gly-Thr-OH; Tat-BECN1. Grades: ≥95%. Molecular formula: C164H251N57O45. Mole weight: 3741.15. | |
| Tat-Beclin-1, scrambled | Beclin-1 peptide is the HIV-1 Nef binding portion of full-length human Beclin-1 protein (amino acids 267-299). Beclin-1 protein is an autophagy inducing agent that triggers cell adaptation, survival, or death. When combined with the cell-permeable peptide, it can successfully enter cells and induce autophagy. Tat-Beclin-1, scrambled will not induce autophagy and can be used as a negative control. Alternative Names: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Val-Gly-Asn-Asp-Phe-Phe-Ile-Asn-His-Glu-Thr-Thr-Gly-Phe-Ala-Thr-Glu-Trp-OH. Grades: ≥95% by HPLC. Molecular formula: C164H251N57O45. Mole weight: 3741.15. | |
| TAT-C (48-57) | It is amino acids 48 to 57 fragment of TAT with an additional cysteine residue at the N-terminus. The peptide contains a protein transduction domain (PTD) that inhibits HSV-1 entry into the HIV Tat protein. The addition of cysteine residue to the N-terminus of the Tat-PTD (Tat-C peptide) improves the antiviral activity against HSV-1 and HSV-2. Tat-C acts extracellular and immediately blocks the entry of adsorptive virus without eluting virions. Alternative Names: H-Cys-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-OH; (Cys47)-HIV-1 tat Protein (47-57); L-cysteinyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginine. Grades: ≥95%. CAS No. 627079-23-6. Molecular formula: C58H114N32O13S. Mole weight: 1499.82. | |
| TAT-cyclo-CLLFVY | TAT-cyclo-CLLFVY has been found to be a HIF-1 dimerization inhibitor and could block protein-protein interaction of recombinant HIF-1α. Alternative Names: TAT-cyclo-CLLFVY; 1446322-66-2; AKOS027470216; PD079835. Grades: ≥95% by HPLC. CAS No. 1446322-66-2. Molecular formula: C111H188N42O24S2. Mole weight: 2559.10. | |
| TAT-cyclo-CLLFVY | TAT-cyclo-CLLFVY is a cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. TAT-cyclo-CLLFVY disrupts HIF-1α/HIF-1β protein-protein interaction with an IC50 of 1.3 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1446322-66-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1420. | |
| TAT-EE3 | TAT-EE3 is a neuroprotective peptide which can uncouple TRPM2-NMDARs interaction. TAT-EE3 inhibits TRPM2-induced enhancement of NMDAR surface expression and current amplitude.TAT-EE3 protects neurons against ischemic injury in vitro and in vivo. TAT-EE3can be used for the study of ischemic stroke[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2899218-49-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P11117. | |
| TAT-Gap19 | TAT-Gap19, a Cx mimetic peptide, is a specific connexin43 hemichannel (Cx43 HC) inhibitor. TAT-Gap19 does not inhibits the corresponding Cx43 GJCs. TAT-Gap19 traverses the blood-brain barrier and alleviate liver fibrosis in mice[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1507930-54-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1136B. | |
| TAT-Gap19 | TAT-Gap19 is a brain penetrating Cx43 hemichannel blocker (IC50 ~7 μM) with no significant affinity for gap junctions or Panx1 channels. Alternative Names: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys-Gln-Ile-Glu-Ile-Lys-Lys-Phe-Lys-OH; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-glutaminyl-L-isoleucyl-L-alpha-glutamyl-L-isoleucyl-L-lysyl-L-lysyl-L-phenylalanyl-L-lysine. Grades: 97%. CAS No. 1507930-54-2. Molecular formula: C119H212N46O26. Mole weight: 2703.28. | |
| TAT-GluA2 3Y | TAT-GluA2 3Y is a blood-brain barrier-permeable AMPA receptor inhibitory peptide that crosses cell membranes via the HIV-1 TAT protein domain. TAT-GluA2 3Y blocks the endocytosis of AMPA receptors, including the internalization of GluA1/GluA2 subunits, by disrupting interactions with the AP2, Brag2 and Syt3-GluA2 complexes, while also inhibiting long-term depression. TAT-GluA2 3Y blocks hypoxia-mediated AMPAR internalization, alleviates A1R-induced persistent synaptic inhibition, and reduces cerebral ischemic volume, neurological deficits and spatial memory deficits. TAT-GluA2 3Y blocks the effect of NLRP3 deficiency on fear generalization, inhibits amphetamine-induced behavioral/neurochemical sensitization, weakens the unconditioned stimulus-conditioned stimulus association of morphine, and promotes the extinction of morphine CPP. TAT-GluA2 3Y can be used in studies related to fear generalization, ischemic stroke, hypoxia, drug addiction and opioid addiction[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1404188-93-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2259. | |
| TAT-GluA2 3Y acetate | TAT-GluA2 3Y acetate is a cell-penetrating peptide containing tyrosine residues. It inhibits the phosphorylation of alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor endocytosis. Alternative Names: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Tyr-Lys-Glu-Gly-Tyr-Asn-Val-Tyr-Gly-OH.CH3CO2H; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-tyrosyl-L-lysyl-L-alpha-glutamyl-glycyl-L-tyrosyl-L-asparagyl-L-valyl-L-tyrosyl-glycine acetic acid. Grades: ≥95%. Molecular formula: C117H189N43O31. Mole weight: 2694.07. | |
| TAT-GluR23A Fusion Peptide | TAT-GluR23A Fusion Peptide is a control inactive peptide that acts as a mutant counterpart to glutamate receptor endocytosis inhibitor (GluR23Y), linked to an 11 amino acid cell permeable HIV Trans-activator of Transcription (TAT) protein transduction domain (PTD). GluR23A is derived from GluR23Y amino acid 869-877, which is substituted for Tyr by Ala and lacks necessary phosphorylation sites. Alternative Names: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Ala-Lys-Glu-Gly-Ala-Asn-Val-Ala-Gly-OH. Grades: ≥95%. Molecular formula: C97H173N43O26. Mole weight: 2357.71. | |
| TAT-GluR23Y | TAT-GluR23Y is a cell penetrating peptide containing tyrosine residues. It inhibits the phosphorylation of alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor endocytosis. Alternative Names: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Tyr-Lys-Glu-Gly-Tyr-Asn-Val-Tyr-Gly-OH; Tat-GluR23Y; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-tyrosyl-L-lysyl-L-alpha-glutamyl-glycyl-L-tyrosyl-L-asparagyl-L-valyl-L-tyrosyl-glycine; TAT-GluA2 3Y. Grades: ≥95%. CAS No. 1404188-93-7. Molecular formula: C115H185N43O29. Mole weight: 2634.01. | |
| TAT-GluR23Y, scrambled | TAT-GluR23Y, scrambled is a control peptide. The synthetic peptide (Tat-Glur23Y), containing tyrosine residues, blocks phosphorylation of AMPA receptor endocytosis. However, the scrambled version does not have blockade properties. Previous studies show that Tat-Glur23Y, scrambled increases stress levels in mice, while Tat-Glur23Y reduces stress when administered. Alternative Names: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Val-Tyr-Lys-Tyr-Gly-Gly-Tyr-Asn-Glu-OH; Tat-GluR23Y, scrambled. Grades: ≥95%. Molecular formula: C115H185N43O29. Mole weight: 2634.01. | |
| TAT-HA2 Fusion Peptide | It is a cell penetrating peptide consisting of amino acids 1 to 20 of influenza A virus hemagglutinin protein (HA2), which is linked to a 10 amino acid cell permeable HIV Trans-activator of Transcription (TAT) protein transduction domain (PTD). TAT-HA2 can be used as a large molecule drug delivery peptide. TAT PTD binds to the cell surface and penetrates the cell membrane through lipid raft dependent macropinocytosis. The HA2 domain is a pH-sensitive lipid membrane destabilizing sequence that enhances endosomal escape and transduction of the fusion peptide. Alternative Names: H-Arg-Arg-Arg-Gln-Arg-Arg-Lys-Lys-Arg-Gly-Gly-Asp-Ile-Met-Gly-Glu-Trp-Gly-Asn-Glu-Ile-Phe-Gly-Ala-Ile-Ala-Gly-Phe-Leu-Gly-OH. Grades: ≥95%. Molecular formula: C149H243N53O39S. Mole weight: 3432.98. | |
| TAT-HA2 Fusion Peptide | TAT-HA2 Fusion Peptide is a peptide-based delivery agent that combines the pH-sensitive HA2 fusion peptide from Influenza and the cell-penetrating peptide TAT from HIV. TAT-HA2 Fusion Peptide is a transactivator of transcription and hemaglutanin for endosomal release. TAT-HA2 Fusion Peptide enhances cellular uptake of macromolecules[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 923954-79-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P4108. | |
| TAT-M2NX | TAT-M2NX (tatM2NX) is a selective inhibitor targeting human TRPM2 channels and exerts inhibitory effects on ischemic stroke. TAT-M2NX reduces H2O2-induced calcium influx via TRPM2 channels. After traumatic brain injury in mice, TAT-M2NX preserves hippocampal long-term potentiation, improves memory function, and reduces infarct volume after middle cerebral artery occlusion, but it shows no effect on female mice. TAT-M2NX can be used in studies related to traumatic brain injury and ischemic stroke[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: tatM2NX. CAS No. 2126166-03-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P5883. | |
| Tat-NR2B9c | Tat-NR2B9c (Tat-NR2Bct; NA-1) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy[1][2][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tat-NR2Bct; NA-1. CAS No. 500992-11-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0117. | |
| TAT-NR2B9c | Tat-NR2B9c (NA-1) is a membrane-permeable postsynaptic density-95 (PSD-95)-binding (decoy) peptide and a neuroprotective agent that can inhibit neuronal excitotoxicity. Alternative Names: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys-Leu-Ser-Ser-Ile-Glu-Ser-Asp-Val-OH; Tat-NR2Bct; Tat-NR2B9c; NA-1; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-seryl-L-seryl-L-isoleucyl-L-alpha-glutamyl-L-seryl-L-alpha-aspartyl-L-valine; Nerinetide. Grades: ≥95%. CAS No. 500992-11-0. Molecular formula: C105H188N42O30. Mole weight: 2518.92. | |
| Tat-NR2B9c TFA | Tat-NR2B9c TFA is a membrane-permeable postsynaptic density-95 (PSD-95)-binding (decoy) peptide and a neuroprotective agent that can inhibit neuronal excitotoxicity. Alternative Names: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys-Leu-Ser-Ser-Ile-Glu-Ser-Asp-Val-OH.TFA; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-seryl-L-seryl-L-isoleucyl-L-alpha-glutamyl-L-seryl-L-alpha-aspartyl-L-valine trifluoroacetic acid; NA-1 TFA. CAS No. 1834571-04-8. Molecular formula: C107H189F3N42O32. Mole weight: 2632.9. | |
| Tat-NR2B9c TFA | Tat-NR2B9c TFA (Tat-NR2Bct TFA) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c TFA disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c TFA also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tat-NR2Bct TFA; NA-1 TFA. CAS No. 1834571-04-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0117A. | |
| TAT-NSF222 Fusion Peptide | This sequence is a N-ethylmaleimide sensitive factor (NSF) peptide that connects to the 11 amino acid cell permeable human immunodeficiency virus (HIV) transactivating regulatory protein (TAT) domain by Gly-Gly-Gly spacer. The peptide contains the NSF domain extending from 222 to 243 amino acids, which is located directly at the amino terminus of the Walker A motif in the NSF D1 domain. ATPase assay shows that TAT-NSF222 inhibits the activity of NSF ATPase. Alternative Names: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Gly-Leu-Asp-Lys-Glu-Phe-Asn-Ser-Ile-Phe-Arg-Arg-Ala-Phe-Ala-Ser-Arg-Val-Phe-Pro-Pro-Glu-OH. Grades: ≥95%. Molecular formula: C187H301N67O47. Mole weight: 4239.89. | |
| TAT-NSF222scr Fusion Polypeptide, scrambled | It is a scrambled TAT-NSF222scr fusion polypeptide. It consists of 11 amino acids from the cell permeable human immunodeficiency virus TAT polypeptide, 3 glycines as a linker, followed by scrambled N-Ethyl-maleimide-sensitive factor (NSF) D1 domain. It is used as a control for the TAT-NSF222 peptide. Alternative Names: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Gly-Glu-Asn-Ser-Phe-Arg-Phe-Leu-Ala-Asp-Ile-Phe-Pro-Ala-Lys-Ala-Phe-Pro-Val-Arg-Phe-Glu-OH. Grades: ≥95%. Molecular formula: C190H298N64O46. Mole weight: 4214.88. | |
| TAT-NSF700 Fusion Peptide | It is a N-Ethyl-maleimide-sensitive factor (NSF) inhibitor fusion polypeptide, which is fused from the 11 amino acid cell permeable HIV transactivation regulatory protein (TAT) domain to the 22 amino acid NSF domain. TAT-NSF700 inhibits thrombin-induced exocytosis of endothelial cells in a dose-responsive manner. Alternative Names: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Gly-Leu-Leu-Asp-Tyr-Val-Pro-Ile-Gly-Pro-Arg-Phe-Ser-Asn-Leu-Val-Leu-Gln-Ala-Leu-Leu-Val-Leu-OH; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-glycyl-glycyl-glycyl-L-leucyl-L-leucyl-L-alpha-aspartyl-L-tyrosyl-L-valyl-L-prolyl-L-isoleucyl-glycyl-L-prolyl-L-arginyl-L-phenylalanyl-L-seryl-L-asparagyl-L-leucyl-L-valyl-L-leucyl-L-glutaminyl-L-alanyl-L-leucyl-L-leucyl-L-valyl-L-leucine. Grades: ≥95%. Molecular formula: C188H318N62O45. Mole weight: 4167.00. | |
| TAT-NSF700scr | TAT-NSF700scr is used as a control peptide to TAT-NSF700 peptide. Compared with TAT-NSF700, it does not inhibit the disassembly activity of NSF, and TAT-NSF700 plays a key role in regulating exocytosis. Alternative Names: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Gly-Ile-Pro-Pro-Val-Tyr-Phe-Ser-Arg-Leu-Asp-Leu-Asn-Leu-Val-Val-Leu-Leu-Leu-Ala-Gln-Leu-OH. Grades: ≥95%. Molecular formula: C186H315N61O44. Mole weight: 4109.95. | |
| TAT-NSF81scr Fusion Polypeptide, scrambled | It is a scrambled peptide containing the TAT domain and 20 of N-Ethyl-maleimide-sensitive factor 81 (NSF81). TAT-NSF81scr is used to measure the effect of the active and control peptides upon NSF activities and exocytosis. Alternative Names: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Gly-Gln-Asp-Gly-Cys-Lys-Tyr-Phe-Ala-Thr-Asp-Glu-Thr-Ile-Met-Lys-Leu-Ser-Ile-Ala-Ile-OH. Grades: ≥97%. Molecular formula: C169H284N58O48S2. Mole weight: 3960.61. | |
| TAT-P110 | TAT-P110, a peptide inhibitor of Drp1-Fis1 interaction, reduces pathology in numerous models of neurodegeneration, ischemia, and sepsis without blocking the physiological functions of Drp1[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: P110. CAS No. 2247617-97-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2280. | |
| TAT P59W | It is a TAT peptide containing tryptophane residues. Alternative Names: Fluo-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Trp-Gln-NH2. Grades: 98%. | |
| TAT peptide | TAT peptide, derived from the transactivator of transcription (TAT) of human immunodeficiency virus, is a cell penetrating peptide (GRKKRRQRRRPQ). Alternative Names: TAT-peptide. Grades: 98%. Molecular formula: C65H124N34O15. Mole weight: 1621.91. | |
| TAT-PiET-PROTAC | TAT-PiET-PROTAC is a proteolysis-targeting chimera (PROTAC)-modified TAT-PiET (HY-P10445), which is a cell-penetrating peptide targeting the extra-terminal (ET) domain of BRD4. TAT-PiET-PROTAC can reduce BRD4 and JMJD6 levels and inhibit cell proliferation. TAT-PiET-PROTAC also resists the endocrine resistance of ERα-positive breast cancer cells. TAT-PiET-PROTAC can be used for the research of cancer, such as breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3036046-04-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P10446. | |
| Tatsinine | Tatsinine is a potential natural compound in natural compound used for the research of various cancers. With its unique chemical structure, it has shown promising anti-tumor activity by inhibiting specific signaling pathways involved in cancer progression. Alternative Names: 20-ethyl-16-methoxy-4-methylaconitane-1,7,8,9,14-pentol. Grades: 97.0%. CAS No. 90038-21-4. Molecular formula: C22H35NO6. Mole weight: 409.523. | |
| TATU | TATU. Alternative Names: O-(7-Azabenzotriazole-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; 2-(3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; 2-(7-Azabenzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; O-(7-Azabenzotriazolyl)-tetramethyluronium tetrafluoroborate; TATU [O-(7-Azabenzotriazole-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate]; ACMC-209vlk; SCHEMBL153586. Grades: 99% (HPLC). CAS No. 873798-09-5. Molecular formula: C10H16BF4N6O. Mole weight: 323.08. | |
| TATU | TATU. Group: Biochemicals. Alternative Names: 1-[Bis (dimethylamino) methylene]-1H-1, 2, 3-triazolo[4, 5-b]pyridinium 3-oxide tetrafluoroborate; O-(7-Azabenzotriazole-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate. Grades: Highly Purified. CAS No. 873798-09-5,873678-56-9. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C10H15N6OBF4. US Biological Life Sciences. | Worldwide |
| TAU-IN-1 | TAU-IN-1 (compound 051) is a TAU protein inhibitor with an EC50 value of 325 nM. TAU-IN-1 can be used in the study of neurodegenerative diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1383373-65-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-13486. | |
| TAU-IN-4 | TAU-IN-4 (compound I1.21) is a potent Tau aggregation inhibitor with a KD of 1.58 μM. TAU-IN-4 can be used in the study of Alzheimers disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2109305-45-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-172973. | |
| TAU-IN-5 | TAU-IN-5 (compound 13) is a TAU protein inhibitor with an EC50 of 0.81 μM. TAU-IN-5 inhibits the formation of tau (2N4R isoform) oligomers and reduces the formation of tau dimers. TAU-IN-5 can be used in the study of Alzheimer's disease (AD) and Parkinson's disease (PD)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3118812-61-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175840. | |
| Tau ligand-1 | Tau ligand-1 (Compound 75) is a ligand for aggregated tau protein that can penetrate the blood-brain barrier[1]. In tissues from patients with Alzheimer's disease, progressive supranuclear palsy, corticobasal degeneration, and Pick's disease, Tau ligand-1 exhibits high affinity for aggregated tau protein, with equilibrium dissociation constant (KD) values ranging from 1 to 3.8 nM[1]. Tau ligand-1 can serve as a potential positron emission tomography (PET) tracer and holds promise for application in positron emission tomography imaging studies of tau-related diseases in the central nervous system[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3063166-64-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-173291. | |
| Tau Peptide (1-16) (human) | Tau peptide (1-16) (human) corresponds to the N-terminus of the nascent Tau protein. Posttranslational modifications include removal of N-terminal Met and acetylation of Ala2. Alternative Names: H-Met-Ala-Glu-Pro-Arg-Gln-Glu-Phe-Glu-Val-Met-Glu-Asp-Met-Ala-Gly-OH. Grades: ≥95%. CAS No. 2022956-53-0. Molecular formula: C77H120N20O28S3. Mole weight: 1870.12. | |
| Tau Peptide (244-274) (Repeat 1 Domain) | During heparin-induced self-aggregation of the four repeat domain peptides (R1-R4) excised from tau, R1, which is similar to the Tau peptide (244-274), shows the strongest resistance to filament formation. Its conformation remains the same. It maintains the same random structure under acidic and neutral conditions. Alternative Names: H-Gln-Thr-Ala-Pro-Val-Pro-Met-Pro-Asp-Leu-Lys-Asn-Val-Lys-Ser-Lys-Ile-Gly-Ser-Thr-Glu-Asn-Leu-Lys-His-Gln-Pro-Gly-Gly-Gly-Lys-OH; L-Glutaminyl-L-threonyl-L-alanyl-L-prolyl-L-valyl-L-prolyl-L-methionyl-L-prolyl-L-alpha-aspartyl-L-leucyl-L-lysyl-L-asparaginyl-L-valyl-L-lysyl-L-seryl-L-lysyl-L-isoleucylglycyl-L-seryl-L-threonyl-L-alpha-glutamyl-L-asparaginyl-L-leucyl-L-lysyl-L-histidyl-L-glutaminyl-L-prolylglycylglycylglycyl-L-lysine. Grades: ≥95%. CAS No. 330456-24-1. Molecular formula: C141H238N42O44S. Mole weight: 3257.63. | |
| Tau Peptide (245-274) (Repeat 1 Domain) | Tau Peptide (245-274) (Repeat 1 Domain). Alternative Names: H-Thr-Ala-Pro-Val-Pro-Met-Pro-Asp-Leu-Lys-Asn-Val-Lys-Ser-Lys-Ile-Gly-Ser-Thr-Glu-Asn-Leu-Lys-His-Gln-Pro-Gly-Gly-Gly-Lys-OH; L-threonyl-L-alanyl-L-prolyl-L-valyl-L-prolyl-L-methionyl-L-prolyl-L-alpha-aspartyl-L-leucyl-L-lysyl-L-asparagyl-L-valyl-L-lysyl-L-seryl-L-lysyl-L-isoleucyl-glycyl-L-seryl-L-threonyl-L-alpha-glutamyl-L-asparagyl-L-leucyl-L-lysyl-L-histidyl-L-glutaminyl-L-prolyl-glycyl-glycyl-glycyl-L-lysine. Grades: ≥95%. CAS No. 1428134-39-7. Molecular formula: C136H230N40O42S. Mole weight: 3129.63. | |
| Tau Peptide (255-314) (Repeat 2 Domain) (human) | Tau Peptide (255-314) (Repeat 2 Domain) (human). Alternative Names: H-Asn-Val-Lys-Ser-Lys-Ile-Gly-Ser-Thr-Glu-Asn-Leu-Lys-His-Gln-Pro-Gly-Gly-Gly-Lys-Val-Gln-Ile-Ile-Asn-Lys-Lys-Leu-Asp-Leu-Ser-Asn-Val-Gln-Ser-Lys-Cys-Gly-Ser-Lys-Asp-Asn-Ile-Lys-His-Val-Pro-Gly-Gly-Gly-Ser-Val-Gln-Ile-Val-Tyr-Lys-Pro-Val-Asp-OH. Grades: ≥95%. CAS No. 2022995-68-0. Molecular formula: C277H467N83O86S. Mole weight: 6368.33. | |
| Tau Peptide (255-314) (Repeat 2 Domain) (human) | Tau Peptide (255-314) (Repeat 2 Domain) (human) (Tau-F protein (255-314)) is a polypeptide. Tau Peptide (255-314) (human) is the 255-314 fragment of Tau-F (also known as Tau-4, the 2N4 isoform), a major isoform of the Tau protein. Tau Peptide (255-314) (human) contains two core driving sequences for Tau aggregation, namely PHF6* (275-280, VQIINK) and PHF6 (306-311, VQIVYK), and spans the C-terminal half of repeat domain R1, the entire repeat domain R2, and the N-terminal half of repeat domain R3 within the microtubule-binding region (MTBR). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tau-F protein (255-314). CAS No. 2022995-68-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P4933. | |
| Tau Peptide (268-282) | Tau Peptide (268-282). Alternative Names: H-His-Gln-Pro-Gly-Gly-Gly-Lys-Val-Gln-Ile-Ile-Asn-Lys-Lys-Leu-OH; L-Histidyl-L-glutaminyl-L-prolylglycylglycylglycyl-L-lysyl-L-valyl-L-glutaminyl-L-isoleucyl-L-isoleucyl-L-asparaginyl-L-lysyl-L-lysyl-L-leucine. Grades: ≥95%. CAS No. 330456-37-6. Molecular formula: C72H125N23O19. Mole weight: 1616.93. | |
| Tau Peptide (273-284) | Tau Peptide (273-284), a Tau fragment containing the PHF6 region, plays a central role in Tau aggregation. Alternative Names: H-Gly-Lys-Val-Gln-Ile-Ile-Asn-Lys-Lys-Leu-Asp-Leu-OH; glycyl-L-lysyl-L-valyl-L-glutaminyl-L-isoleucyl-L-isoleucyl-L-asparagyl-L-lysyl-L-lysyl-L-leucyl-L-alpha-aspartyl-L-leucine. Grades: ≥95%. CAS No. 1663490-91-2. Molecular formula: C62H113N17O17. Mole weight: 1368.68. | |
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