A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Taraxerol, isolated from the herb of Taraxacum mongolicum Hand. Mazz., is a cancer chemopreventive agent. Uses: Ache activity; antiulcer. Synonyms: alnulin; D-Friedoolean-14-en-3beta-ol; skimmiol; (3β,13α)-13-Methyl-27-norolean-14-en-3-ol; (3β)-D-Friedoolean-14-en-3-ol. Grade: 98.5%. CAS No. 127-22-0. Molecular formula: C30H50O. Mole weight: 426.7.
Taraxerol
Taraxerol is isolated from Taraxacum mongolicum, and has anti-inflammtory and anti-cancer effects. Taraxerol attenuates acute inlammation through inhibition of NF-κB signaling pathway. Taraxerol induces cell apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 127-22-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2477.
taraxerol synthase
The enzyme gives taraxerol, β-amyrin and lupeol in the ratio 70:17:13. Group: Enzymes. Synonyms: RsM2; (S)-2,3-epoxysqualene mutase (cyclizing, taraxerol-forming). Enzyme Commission Number: EC 5.4.99.35. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5576; taraxerol synthase; EC 5.4.99.35; RsM2; (S)-2,3-epoxysqualene mutase (cyclizing, taraxerol-forming). Cat No: EXWM-5576.
Taraxerone
Taraxerone is isolated from the herb of Taraxacum mongolicum Hand. Mazz. It can prevent catalase and superoxide dismutase, and reduce glutathione concentration. Synonyms: D-Friedoolean-14-en-3-one; Taraxera-14-ene-3-one; Taraxeron; 27-Norolean-14-en-3-one,13-methyl-, (13a)-; Tarxerone; 27-Norolean-14-en-3-one, 13-methyl-, (13α)-. Grade: 98.5%. CAS No. 514-07-8. Molecular formula: C30H48O. Mole weight: 424.7.
Tarcocimab
Tarcocimab (OG1953) is a humanized anti-VEGFA monoclonal antibody (IgG1 type). Tarcocimab is available for research in retinal vein occlusion (RVO) and wet age-related macular degeneration (AMD). Uses: Scientific research. Category: Signaling pathways. Alternative Names: OG1953. CAS No. 2408661-40-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99576.
Tarenflurbil
Tarenflurbil ((R)-Flurbiprofen) is the R-enantiomer of the racemate NSAID Flurbiprofen, Tarenflurbil ((R)-Flurbiprofen) inhibits the binding of [3H]9-cis-RA to RXRα LBD with IC50 of 75 μM. Tarenflurbil can be used for Alzheimer's disease research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-Flurbiprofen; MPC7869. CAS No. 51543-40-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-10291.
Tarextumab
Tarextumab (OMP-59R5) is a cross-reactive, fully human IgG2 antibody that selectively inhibits Notch2 and Notch3 signaling. Tarextumab demonstrates broad-spectrum antitumor efficacy in xenograft models of epithelial tumors. Tarextumab can be used for the study of pancreatic cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OMP 59R5; Anti-Human NOTCH2 Recombinant Antibody. CAS No. 1359940-55-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99320.
Targapremir-210
Targapremir-210 (TGP-210) is a potent and selective miR-210 (miRNA-210, microRNA-210) inhibitor. Targapremir-210 inhibits pre-miR-210 processing with high binding affinity (Kd~200 nM)[1]. Targapremir-210 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TGP-210. CAS No. 1049722-30-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15861.
Targefrin
Targefrin is a potent EphA2-targeting agent, acts as an antagonist. Targefrin binds EphA2-LBD with 21 nM dissociation constant and an IC50 value of 10.8 nM. Targefrin induces cellular receptor internalization and degradation in several pancreatic cancer cell lines[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3031514-44-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3717.
Targeted Therapy Drug Library
116 tumor-targeted drugs that can be used for high-throughput and high-content screening. - Targets include EGFR, VEGFR, c-Met, Bcr-Abl, HER2, etc. - All compounds have known and good biological activity, safety and bioavailability. - Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc. - Various detection techniques such as NMR, HPLC/LCMS to ensure correct structure, high purity and reduce the false-positive rates. Uses: Scientific use. Product Category: L2152. Categories: Targeted Therapy Drug Libraries.
Target-Focused Phenotypic Screening Library
A unique collection of 1832 annotated bioactive compounds with clear targets, suitable for phenotypic screening?- Cover more than 600 drug targets, Structurally diverse?- 2-4 structurally diversified compounds for the same annotated 'on-target' to increase the success rate of target identification (enables the generation of much stronger target-phenotype hypotheses); - Detailed information about compound structure, target, activity, etc. ?- NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L9500. Categories: Target-Focused Phenotypic Screening Libraries.
Taribavirin hydrochloride
Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 40372-00-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10545A.
Tariquidar
Tariquidar (XR9576) is a potent and specific inhibitor of P-glycoprotein (P-gp) with the high affinity (Kd=5.1 nM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XR9576. CAS No. 206873-63-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10550.
Tariquidar methanesulfonate, hydrate (XR9576 methanesulfonate, hydrate) is a potent and specific inhibitor of P-glycoprotein (P-gp) with a Kd of 5.1 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XR9576 methanesulfonate, hydrate. CAS No. 625375-83-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-10550A.
Tariquidar (Standard)
Tariquidar (Standard) is the analytical standard of Tariquidar. This product is intended for research and analytical applications. Tariquidar (XR9576) is a potent and specific inhibitor of P-glycoprotein (P-gp) with the high affinity (Kd=5.1 nM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XR9576 (Standard). CAS No. 206873-63-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10550R.
Tarlatamab
Tarlatamab (AMG-757) is a bispecific T-cell engager (BiTE) antibody targeting delta-like ligand 3 (DLL3). DLL3 is a target that is selectively expressed in small-cell lung cancer (SCLC) tumors, but with minimal normal tissue expression. Tarlatamab has the KDs of 0.64 nM and 0.50 nM for human and nonhuman primate (NHP) DLL3, respectively. Tarlatamab has the KDs of 14.9 nM and 12 nM for human and NHP CD3, respectively. Tarlatamab is a first-in-class HLE BiTE immuno-oncology therapy targeting DLL3 and has the potential for SCLC research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMG-757. CAS No. 2307488-83-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99575.
Tarloxotinib bromide
Tarloxotinib bromide (TH-4000) is an irreversible EGFR/HER2 inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TH-4000. CAS No. 1636180-98-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17632.
Tarlox-TKI
Tarlox-TKI, the active metabolite of Tarloxotinib, is an irreversible pan-ErbB TKI (Tarlox-TKI)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2135696-72-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-43533.
Tarocin A1
≥98% (HPLC). Uses: For analytical and research use. Category: Fluorescence/luminescence spectroscopy. Mole weight: 496.40. Catalog: IAR4245330.
Tartaric acid. CAS No. 147-71-7. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Tartaric acid
Tartaric acid. Uses: For analytical and research use. CAS No. 87-69-4. Mole weight: 150.09. Catalog: AP87694-B.
Tartaric Acid
Tartaric acid occurs as colorless monoclinic crystals, or a white or almost white crystalline powder. It is odorless, with an extremely tart taste. Synonyms: Acidum tartaricum; L-(+)-2 , 3-dihydroxybutanedioic acid; (2R, 3R)- dihydroxybutane-1, 4-dioic acid; d- tartaric acid; 2 , 3-dihydroxysuccinic acid; L-(+)- tartaric acid. CAS No. 87-69-4. Product ID: PE-0449. Molecular formula: C4H6O6. Mole weight: 150.09. Category: Effervescents. Product Keywords: Pharmaceutical Excipients; Excipients for Liquid Dosage Form; Tartaric Acid; Effervescents; Effervescents; C4H6O6; 87-69-4; 87-69-4. UNII: W4888I119H. Chemical Name: (2R, 3R)-2, 3-Dihydroxybutanedioic acid. Administration route: IM and IV; oral; sublingual; topical; rectal and vaginal. Dosage Form: IM and IV injections; oral solutions, syrups and tablets; sublingual tablets; topical films; rectal and vaginal preparations. Stability and Storage Conditions: The bulk material is stable and should be stored in a well-closed container in a cool, dry place. Source and Preparation: Tartaric acid occurs naturally in many fruits as the free acid or in combination with calcium, magnesium, and potassium. Commercially, L-(+)-tartaric acid is manufactured from potassium tartrate (cream of tartar), a by-product of wine making.Potassium tartrate is treated with hydrochloric acid, followed by the addition of a calcium salt to produce insoluble calcium tartrate. This precipitate is th
Tartaric Acid
Tartaric Acid. CAS No. 87-69-4. Molecular Formula HOOC(CHOH)2COOH. Chemical Reagents
Cater Chemicals Corp. Illinois IL
Tartaric Acid
TARTARIC ACID, L, ACS Reagent, powder, (Synonym: 2,3-Dihydroxybutanedioic Acid), Formula: HO2CCH(OH)CH(OH)CO2H. CAS No. 87-69-4. Noah Chemicals San Antonio, Texas. ISO 9001:2015 Certified. Request a Quote Today!
Tartaric Acid Methyl Ester is useful for developing stabilizers as additives in methanol-gasoline. In addition, Tartaric Acid Methyl Ester can be used to synthesize novel enantiopure γ/δ-amino acid via trans-acetalization. Group: Biochemicals. Grades: Highly Purified. CAS No. 3333-46-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C5H8O6. US Biological Life Sciences.
Worldwide
Tartary Buckwheat Extract
Tartary Buckwheat Extract. Applications: Used for health care products, dietary supplements, reduce blood press, antioxidant. Group: Others. Synonyms: Tartary Buckwheat Extract; Fagopyrum tataricum (L.) Gaertn. Purity: 30%-70% Total Flavonoid By UV. Appearance: Yellow green fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Fruit. Species: Fagopyrum tataricum (L.) Gaertn. Tartary Buckwheat Extract; Fagopyrum tataricum (L.) Gaertn; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-099.
Tart Cherry Fruit Powder & 4:1
Tart Cherry Fruit Powder & 4:1.
CA, FL & NJ
tartrate decarboxylase
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. Group: Enzymes. Synonyms: (R,R)-tartrate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.73. CAS No. 124248-30-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4821; tartrate decarboxylase; EC 4.1.1.73; 124248-30-2; (R,R)-tartrate carboxy-lyase. Cat No: EXWM-4821.
tartrate dehydrogenase
meso-tartrate and (R,R)-tartrate act as substrates. Requires Mn2+ and a monovalent cation. Group: Enzymes. Synonyms: mesotartrate dehydrogenase. Enzyme Commission Number: EC 1.1.1.93. CAS No. 37250-29-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0377; tartrate dehydrogenase; EC 1.1.1.93; 37250-29-6; mesotartrate dehydrogenase. Cat No: EXWM-0377.
tartrate epimerase
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on hydroxy acids and derivatives. This enzyme participates in glyoxylate and dicarboxylate metabolism. Group: Enzymes. Synonyms: tartaric racemase. Enzyme Commission Number: EC 5.1.2.5. CAS No. 37318-33-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5392; tartrate epimerase; EC 5.1.2.5; 37318-33-5; tartaric racemase. Cat No: EXWM-5392.
Tartrazine
Tartrazine. Group: Biochemicals. Alternative Names: 4,5-Dihydro-5-oxo-1-(4-sulfophenyl)-4-[2-(4-sulfophenyl)diazenyl]-1H-pyrazole-3-carboxylic acid sodium salt; Aizen tartrazine; Acid yellow 23. Grades: Highly Purified. CAS No. 1934-21-0. Pack Sizes: 100g, 250g, 500g, 1Kg, 2Kg. Molecular Formula: C16H9N4Na3O9S2. US Biological Life Sciences.
Worldwide
Tartrazine
Tartrazine. Alternative Names: 3-Carboxy-5-hydroxy-1-p-sulfophenyl-4-p-sulfophenylazopyrazoletrisodium salt, Acid Yellow 23, CI 19140. CAS No. 1934-21-0. Product ID: ALC-FP-1934210. Molecular formula: C16H9N4O9S2·3Na. Alfa Chemistry - ISO 9001:32057 Certified.
Tartrazine (Acid Yellow 23; FD&C Yellow No. 5) is an orally active azo acid dye, orange-yellow powder, soluble in water and turns yellow. Tartrazine is mainly used as a synthetic lemon yellow azo dye for food coloring. Tartrazine is the most stable colorant.Tartrazine induces mitochondria-mediated Apoptosis. Tartrazine can cause neurodevelopmental toxicity, cytotoxicity, and genotoxicity[1][2][3][4][5][6][7][8][9][10][11]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acid Yellow 23; FD&C Yellow No. 5. CAS No. 1934-21-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-D0257.
Tartrazine (For Biological Stains and Dyes)
Tartrazine (For Biological Stains and Dyes). Uses: For analytical and research use. CAS No. 1934-21-0. Molecular formula: C16H9N4Na3O9S2. Mole weight: 534.36. Catalog: APB1934210.
tartronate O-hydroxycinnamoyltransferase
4-Coumaroyl-CoA (4-hydroxycinnamoyl-CoA), caffeoyl-CoA (3,4-dihydroxycinnamoyl-CoA) and feruloyl-CoA (4-hydroxy-3-methoxycinnamoyl-CoA) can also act as donors for the enzyme from the mung bean (Vigna radiata). Group: Enzymes. Synonyms: tartronate sinapoyltransferase; hydroxycinnamoyl-coenzyme-A:tartronate hydroxycinnamoyltransferase. Enzyme Commission Number: EC 2.3.1.106. CAS No. 102484-57-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2044; tartronate O-hydroxycinnamoyltransferase; EC 2.3.1.106; 102484-57-1; tartronate sinapoyltransferase; hydroxycinnamoyl-coenzyme-A:tartronate hydroxycinnamoyltransferase. Cat No: EXWM-2044.
tartronate-semialdehyde synthase
A flavoprotein. Group: Enzymes. Synonyms: tartronate semialdehyde carboxylase; glyoxylate carbo-ligase; glyoxylic carbo-ligase; hydroxymalonic semialdehyde carboxylase; tartronic semialdehyde carboxylase; glyoxalate carboligase; glyoxylate carboxy-lyase (dimerizing); glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming). Enzyme Commission Number: EC 4.1.1.47. CAS No. 9027-24-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4792; tartronate-semialdehyde synthase; EC 4.1.1.47; 9027-24-1; tartronate semialdehyde carboxylase; glyoxylate carbo-ligase; glyoxylic carbo-ligase; hydroxymalonic semialdehyde carboxylase; tartronic semialdehyde carboxylase; glyoxalate carboligase; glyoxylate carboxy-lyase (dimerizing); glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming). Cat No: EXWM-4792.
TAS0612 is the orally active inhibitor of RSK, AKT and S6K. TAS0612 has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2148902-58-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-157133.
TAS-103
TAS-103 is a dual inhibitor of DNA topoisomerase I/II, used for cancer research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-247615. CAS No. 174634-08-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13758.
TAS-103 dihydrochloride
TAS-103 dihydrochloride is a dual inhibitor of DNA topoisomerase I/II, used for cancer research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-247615 dihydrochloride. CAS No. 174634-09-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13758A.
TAS-114
TAS-114 is an orally active dual dUTPase/dihydropyrimidine dehydrogenase (DPD) inhibitor, can improving the therapeutic efficacy of fluoropyrimidine[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1198221-21-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124062.
TAS-116 (Pimitespib)
Pimitespib (TAS-116) is a novel, small-molecule HSP90 inhibitor which inhibits geldanamycin-FITC binding to HSP90 proteins with Ki values of 34.7 nmol/L, 21.3 nmol/L, >50,000 nmol/L, and >50,000 nmol/L for HSP90α, HSP90β, GRP94, and TRAP1, respectively. Furthermore, TAS-116 does not inhibit other ATPases such as HSP70 (IC50 >200 μmol/L). Group: Inhibitors. CAS No. 1260533-36-5. Pack Sizes: 5mg. Product ID: S7716. Formula: C25H26N8O. Smiles: CCC1=C(C=CC(=C1)C(=O)N)N2C3=NC=CC(=C3C(=N2)C(C)C)N4C=C(N=C4)C5=CN(N=C5)C. Storage Conditions: 3 years -20°C powder.
United States; Europe
TAS-119
TAS-119 is a potent, selective and orally active Aurora A inhibitor with an IC50 of 1.0 nM. TAS-119 shows high selectivity for Aurora A over other protein kinases, including Aurora B (IC50 of 95 nM). TAS-119 has potent antitumor activites[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1453099-83-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137377.
TAS1553
TAS1553 is a potent, orally active protein-protein interaction (PPI) inhibitor with an IC50 values of 0.0396 μM. TAS1553 inhibits DNA replication and reduces intracellular dATP pool. TAS1553 induces apoptosis. TAS1553 can be used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2166023-31-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150785.
TAS2R14 agonist-2
TAS2R14 agonist-2 (compound 28.1) is a potent and selective TAS2R14 agonist with an EC50 value of 72 nM. TAS2R14 agonist-2 reveals marked selectivity over a panel of 24 non-bitter taste human G protein-coupled receptors. TAS2R14 agonist-2 can be used for the studies of asthma or chronic obstructive pulmonary disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2883007-69-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153265.
TAS 301
TAS 301. Group: Biochemicals. Grades: Purified. CAS No. 193620-69-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TAS4464
TAS4464 is a long-acting, highly selective covalent inhibitor targeting NEDD8-activating enzyme (NAE) (IC50=0.955 nM), and also inhibits CAII with an IC50 of 0.73 μM, which is less potent than MLN4924 (HY-70062). The IC50 values of TAS4464 against other E1 enzymes UAE and SAE are 449 nM and 1280 nM, respectively. TAS4464 targets NEDD8 in an ATP-dependent manner to inhibit NAE, blocks the neddylation pathway, causes accumulation of CRL ubiquitin ligase substrates (such as CDT1, p27, phosphorylated IκBα), and further induces tumor cell apoptosis. TAS4464 exhibits antiproliferative and cytotoxic effects, and has broad-spectrum antitumor activity against various hematologic and solid tumor cell lines as well as patient-derived tumor cells. TAS4464 has a wide selcetive window, without obvious toxicity. TAS4464 can be used in the research of hematologic malignancies (leukemia, lymphoma, multiple myeloma, etc.) and solid tumors (small cell lung cancer, colorectal cancer, sarcoma, endometrial cancer, ovarian cancer, etc.)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1848959-10-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-128586.
Taselisib
Taselisib (GDC-0032) is a potent PI3K inhibitor targets PIK3CA mutations, with Kis of 0.12 nM, 0.29 nM, 0.97 nM, and 9.1 nM for PI3Kδ, PI3Kα, PI3Kγ and PI3Kβ, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GDC-0032; RG-7604. CAS No. 1282512-48-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13898.
Tasimelteon
Tasimelteon (BMS-214778) is an orally active and selective dual melatonin receptor agonist (DMRA). Tasimelteon has 2.1-4.4 times greater affinity for the MT2 receptor than for the MT1 receptor. Tasimelteon is a circadian regulator and has the potential for Non-24-Hour Sleep-Wake Disorder (Non-24)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-214778; VEC-162. CAS No. 609799-22-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-14803.
TASIN-1
TASIN-1 is a selective inhibitor of truncated APCTR (adenomatous polyposis coli gene) that exerts cytotoxic effects by inhibiting cholesterol biosynthesis. TASIN-1 specifically targets colorectal cancer (CRC) cells carrying APC truncated mutations, while having no significant toxicity to wild-type APC cells. TASIN-1 exerts cytotoxic effects by targeting Emopamil binding protein (EBP) to inhibit cholesterol biosynthesis, triggering endoplasmic reticulum (ER) stress, reactive oxygen species (ROS) generation, and JNK-mediated apoptosis, and inhibiting Akt survival signaling. TASIN-1 can be used to prevent and intervene in APC mutant colorectal cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 792927-06-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116572A.
TASIN-30
TASIN-30 is a selective EBP inhibitor with an EC50 of 0.097 μM. TASIN-30 blocks the production of 7-dehydrocholesterol (7-DHC) and downstream cholesterol biosynthesis processes. TASIN-30 depletes downstream sterols, disrupts the integrity of lipid rafts in tumor cells, accelerates intracellular cholesterol consumption, and inhibits tumor cell proliferation. TASIN-30 induces ferroptosis and apoptosis by reducing 7-DHC levels and increasing phospholipid peroxidation. TASIN-30 achieves tumor suppression in nude mice with osteosarcoma. TASIN-30 can be used in cancer-related research such as colorectal cancer and osteosarcoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1678515-93-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164561.
Tasisulam
Tasisulam is a anticancer agent and induces apoptosis via the intrinsic pathway, resulting in cytochrome c release and caspase-dependent cell death. Tasisulam inhibits mitotic progression and induces vascular normalization[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY 573636. CAS No. 519055-62-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14804.
Tasosartan
Tasosartan is a long-acting angiotensin II (AngII) receptor antagonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: WAY-ANA 756. CAS No. 145733-36-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-A0250.
Taspine
Taspine is an alkaloid isolated from Radix et Rhizoma Leonticis. It shows various pharmaceutical properties: bacteriostatic, wound healing, cytotoxicity, immunosuppression, acetilcholinesterase inhibition, and inhibition of the activity of tumor angiogenesis. Used as human acid beta-glucosidase inhibitor and for the treatment of Gaucher disease. Group: Biochemicals. Alternative Names: 1-[2-(Dimethylamino)ethyl]-3,8-dimethoxy-[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione; Thaspine; NSC 688259; Taspin. Grades: Highly Purified. CAS No. 602-07-3. Pack Sizes: 5mg. US Biological Life Sciences.