A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the suppliers website for prices or more information.
| Product | Description | |
|---|---|---|
| Topiroxostat Impurity E | Topiroxostat Impurity E. Uses: For analytical and research use. CAS No. 94413-64-6. Molecular formula: C8H6N2O2. Mole weight: 162.15. Catalog: APB94413646. |  |
| Topiroxostat Impurity H | Topiroxostat Impurity H. Uses: For analytical and research use. Molecular formula: C13H8N6O. Mole weight: 264.25. Catalog: APB09968. | |
| Topobexin | Topobexin is a TOP2B-selective inhibitor with IC50 values of 0.19 μM and 4.8 μM for TOP2B and TOP2A (DNA decatenation assay). Topobexin binds to non-homologous residues in the obex pocket and targets the ATPase domain of TOP2B. Topobexin prevents anthracycline-induced DNA double-strand break formation, apoptotic signaling mediated by caspase 3/7, 8 and 9, cardiomyocyte morphological changes, mitochondrial depolarization/loss, left ventricular systolic dysfunction, extracellular matrix remodeling, fibrotic alterations, and increases in plasma cardiac troponin T and BNP. Topobexin does not impair the antiproliferative effects of anthracyclines in cancer cells, exhibits no intrinsic cytotoxicity in cardiomyocytes, and is well tolerated in rabbits. Topobexin can be used in studies related to anthracycline-induced cardiotoxicity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3076446-44-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-174374. |  |
| Topoisomerase I from E. coli, Recombinant | Topoisomerase I relaxes supercoiled DNA molecules. The enzyme initiates transient breakages and rejoins of phosphodiester bonds in superhelical turns of closed-circular DNA. Enzyme activity is independent of right-and left-handed superhelices. Topoisomerase i (e. coli) catalyzes the relaxation of negatively supercoiled dna. topoisomerase i has also been implicated in knotting and unknotting dna and in linking complementary rings of single-stranded dna into double-stranded rings. the intact holoenzyme is a 97 kda protein. Group: Enzymes. Synonyms: Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. TOPO I. Storage: at -20°C. Form: 50 mM KCl, 10 mM Tris-HCl (pH 7.5), 35 mM (NH4)2SO4, 0.1 mM EDTA, 1 mM DTT and 50% glycerol. Source: E. coli. Species: E. coli. Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. Cat No: NATE-1339. |  |
| Topoisomerase I from Human, Recombinant | Topoisomerase I relaxes supercoiled DNA molecules. The enzyme initiates transient breakages and rejoins of phosphodiester bonds in superhelical turns of closed-circular DNA. Enzyme activity is independent of right-and left-handed superhelices. Group: Enzymes. Synonyms: Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. TOPO I. Stability: Stable for 3 months undiluted. Storage: Store at -80°C. It is recommended that the enzyme is aliquoted to avoid repeated freeze-thaw cycles. Source: Baculovirus-infected insect cells (Spodoptera frugiperda). Species: Human. Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. Cat No: NATE-1340. | |
| Topoisomerase II-alpha-b (828-836) | Topoisomerase II-alpha-b (828-836) is a peptide derived from Topoisomerase II-alpha-b. Topoisomerase II-alpha is an enzyme that controls and alters the topologic states of DNA during transcription. Human topoisomerase II enzymes are targets for a number of widely used anticancer agents. |  |
| Topoisomerase II Inhibitor (BNS-22) | A potent, 2H-chromen-2-one small molecule inhibitor that is selective for TOP2 (IC50=2.8uM and 0.42uM for TOP2a and TOP2b, respectively). Unlike TOP2 poisons such as etoposide, it does not lead to DNA damage associated with DNA Double-Strand Breaks, as evidenced by the lack of y-H2AX accumulation but instead inhibits kinetoplast DNA decatenation in vitro. This compound affects cell cycle at the M phase and disturbs mitotic spindle formation in HeLa cells at 3-10uM. It also exhibits significant anti-proliferative activities against several human cancer cell lines. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Topoisomerase I inhibitor 8 | Topoisomerase I inhibitor 8 is a potent topoisomerase I inhibitor. Topoisomerase I inhibitor 8 is a hexacyclic analogue of camptothecin, and displays cytotoxic effect against tumor cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 210346-40-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-148058. | |
| Topopyrone A | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone A selectively inhibits topoisomerase I with the IC50 of 1.22 ng/mL. It also has anti-Gram-positive bacteria activity. Molecular formula: C18H9ClO7. Mole weight: 372.71. | |
| Topopyrone B | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone B selectively inhibits topoisomerase I with the IC50 of 0.15 ng/mL. It also has anti-Gram-positive bacteria activity and it has a strong inhibitory effect on herpes virus, especially varicella zoster virus (VZV). Molecular formula: C18H9ClO7. Mole weight: 372.71. | |
| Topopyrone C | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone C selectively inhibits topoisomerase I with the IC50 of 4.88 ng/mL. It also has anti-Gram-positive bacteria activity. Molecular formula: C18H10O7. Mole weight: 338.27. | |
| Topopyrone D | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone A selectively inhibits topoisomerase I with the IC50 of 19.63 ng/mL. Molecular formula: C18H10O7. Mole weight: 338.27. | |
| Topostatin | Topostatin is originally isolated from Thermomonos pora alba No. 1520. It has inhibitory effects on human tumor cells, and the IC50 of SNB-75 and SNB-78 were 0.4 μmol/L and 7 μmol/L, respectively. Molecular formula: C36H58N4O11S. Mole weight: 754.93. | |
| Topotecan | Topotecan (SKF 104864A; NSC 609669) is an orally active and potent Topoisomerase I inhibitor. Topotecan induces cell cycle arrest in G0/G1 and S phases and promotes apoptosis. Topotecan shows anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKF 104864A; NSC 609669. CAS No. 123948-87-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13768. | |
| Topotecan | Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. It has also been used for in vitro apoptosis assays in PA317 cells. Synonyms: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, (4S)-; (4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, (S)-; (S)-Topotecan; 10-Hydroxy-9-[(dimethylamino)methyl]-(20S)-camptothecin; 9-(N,N-Dimethylaminomethyl)-10-hydroxycamptothecin; Evotopin; Hycamptamine; Hycamptin; Nogitecan; NSC 609699; Potactasol; SKF 104864; SKF-S 104864; TopoCED; Topophore C; Topotecan lactone; ZINC 1611274. Grade: ≥95%. CAS No. 123948-87-8. Molecular formula: C23H23N3O5. Mole weight: 421.45. | |
| Topotecan acid sodium salt | Topotecan acid sodium salt. Alternative Names: TOPOTECAN ACID SODIUM SALT. CAS No. 132877-29-3. Purity: 96%. Product ID: ACM132877293. Molecular formula: C23H24N3O6.Na. Mole weight: 461.448. IUPAC Name: (2S)-2-[1-[(dimethylamino)methyl]-2-hydroxy-8-(hydroxymethyl)-9-oxo-11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoic acid. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Topotecan carboxylic acid sodium salt | Topotecan carboxylic acid sodium salt. Alternative Names: 1-[(Dimethylamino)methyl]-α-ethyl-9,11-dihydro-α,2-dihydroxy-8-(hydroxymethyl)-9-oxo-indolizino[1,2-b]quinoline-7-acetic Acid. CAS No. 123949-08-6. Purity: 96%. Product ID: ACM123949086. Molecular formula: C23H24N3NaO6. Mole weight: 461.44. IUPAC Name: sodium;(2S)-2-[1-[(dimethylamino)methyl]-2-hydroxy-8-(hydroxymethyl)-9-oxo-11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoate. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Topotecan carboxylic acid sodium salt | Topotecan carboxylic acid sodium salt. Group: Biochemicals. Alternative Names: 1-[ (Dimethylamino)methyl]-a-ethyl-9, 11-dihydro-a, 2-dihydroxy-8- (hydroxymethyl)-9-oxo-indolizino[1, 2-b]quinoline-7-acetic acid. Grades: Highly Purified. CAS No. 123949-08-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C23H24N3NaO6. US Biological Life Sciences. | Worldwide |
| Topotecan-d5 | Labeled Topotecan. A DNA topoisomerase I inhibitor; semisynthetic analog of Camptothecin. Antineoplastic. Group: Biochemicals. Alternative Names: (4S)-10-[ (Dimethylamino)methyl]-4- (ethyl-d5)-4, 9-dihydroxy-1H-pyrano[3, 4, 6-7]indolizino[1, 2-b]quinoline-3, 14 (4H, 12H)-dione; NSC-609669-d5; SKF-104864A-d5; Hycamtin-d5. Grades: Highly Purified. CAS No. 1133355-98-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Topotecan-[d5] | Topotecan-[d5] is the labelled analogue of Topotecan. Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. Uses: Labelled topotecan (t542500). a dna topoisomerase i inhibitor; semisynthetic analog of camptothecin. antineoplastic. Synonyms: Topotecan D5. Grade: 95% atom D. CAS No. 1133355-98-2. Molecular formula: C23H18D5N3O5. Mole weight: 426.48. | |
| Topotecan-d6 | Labelled Topotecan, a DNA topoisomerase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1044904-10-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Topotecan-[d6] | One isotopic labelled form of Topotecan, which is a topoisomerase I inhibitor and has been found to be an effective antineoplastic agent. Synonyms: (4S)-10-[(Dimethylamino-d6)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4',6-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; NSC-609669-d6; SKF-104864A-d6; Hycamtin-d6. Grade: 95% by HPLC; 98% atom D. CAS No. 1044904-10-0. Molecular formula: C23H17D6N3O5. Mole weight: 427.48. | |
| Topotecan HCl | Topotecan HCl. Group: Biochemicals. Alternative Names: (4S)-10-[ (Dimethylamino)methyl]-4-ethyl-4, 9-dihydroxy-1H-pyrano[3', 4', 6-7]indolizino[1, 2-b]quinoline-3, 14 (4H, 12H)-dione hydrochloride; NSC-609669; SKF-104864A. Grades: Highly Purified. CAS No. 119413-54-6. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C23H24ClN3O5. US Biological Life Sciences. | Worldwide |
| Topotecan hydrochloride | Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. Uses: Topoisomerase i inhibitors. Synonyms: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, hydrochloride (1:1), (4S)-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (4S)-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (S)-; (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[l,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride; Hycamtin; Nogitecan hydrochloride; NSC 609669; SKF 104864A; SKFS 104864A; Topotecan chlorohydrate; Xinze. Grade: >98%. CAS No. 119413-54-6. Molecular formula: C23H24ClN3O5. Mole weight: 457.91. | |
| Topotecan hydrochloride | Topotecan hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 119413-54-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Topotecan hydrochloride | Topotecan hydrochloride. Alternative Names: Topotecan hydrochloride. CAS No. 119413-54-4. Purity: 96%. Product ID: ACM119413544. Molecular formula: C23H24ClN3O5. Mole weight: 457.90700. IUPAC Name: Topotecan HCl. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Topotecan hydrochloride | Topotecan hydrochloride. Alternative Names: 1,4-Di[4-(3-phenoxypropoxy)-2-butynyl]piperazine. CAS No. 119413-54-6. Purity: 98%. Product ID: ACM119413546. Molecular formula: C23H24ClN3O5. Mole weight: 457.91. IUPAC Name: (19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Topotecan hydrochloride | Topotecan Hydrochloride (SKF 104864A Hydrochloride) is a Topoisomerase I inhibitor with potent antineoplastic activities. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKF 104864A hydrochloride; NSC 609669 hydrochloride. CAS No. 119413-54-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13768A. | |
| Topotecan Hydrochloride | Topotecan Hydrochloride. CAS No. 12948-87-8. Purity: 99.8%. Product ID: ACM12948878. Molecular formula: ClH. Mole weight: 36.46094;g/mol. IUPAC Name: chlorane. ECNumber: 231-595-7. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Topotecan Hydrochloride Liposome (PEGylated) | Topotecan Hydrochloride (TPT) is a semi-synthetic derivative of the plant alkaloid camptothecin (CPT) with cytotoxic properties. Like other drugs in the CPT family, TPT is a specific inhibitor of topoisomerase I, causing lethal DNA damage in the S phase of mitosis. Liposome preparation and anti-tumor activity research. This product is a pre-formulated liposome encapsulating Topotecan Hydrochloride. It is only for research purposes. Group: Drug-loaded liposome. |  |
| Topotecan Related Compound C | Topotecan Related Compound C. Uses: For analytical and research use. CAS No. 7689-3-4. Mole weight: 348.35. Catalog: AP7689034-A. | |
| Topotecan (SKF 104864A) | Topotecan(NSC609699,Nogitecan,SKFS 104864A) is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases. Group: Inhibitors. Alternative Names: NSC609699,Nogitecan,SKFS 104864A. CAS No. 123948-87-8. Pack Sizes: 25mg. Product ID: S9321. Formula: C23H23N3O5. Smiles: CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O. Storage Conditions: 3 years -20°C powder. |  United States; Europe |
| TOPS | TOPS is a chromogenic substrate. TOPS undergoes an oxidative coupling reaction with 4-aminoantipyrine in the presence of H2O2 and nanocrystalline cobalt selenide. TOPS is used in studies related to uric acid detection[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 40567-80-4. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-15933. | |
| Torachrysone | Torachrysone is a natural phenol isolated from the seeds of Cassia obtusifolia. Synonyms: 2-Acetyl-3-methyl-6-methoxynaphthalene-1,8-diol. Grade: >97%. CAS No. 22649-04-3. Molecular formula: C14H14O4. Mole weight: 246.3. | |
| Torachrysone | Torachrysone. Group: Biochemicals. Grades: Highly Purified. CAS No. 22649-04-3. Pack Sizes: 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| Torachrysone 8-O-glucoside | Torachrysone 8-O-glucoside is a natural compound found in the rhizoma of Rheum officinale L. For its inhibitory activities of alpha-glucosidase, it may be used for the treatment of type 2 diabetes. Uses: Anti-diabetes. Synonyms: 7-Acetyl-8-hydroxy-3-methoxy-6-methyl-1-naphthyl β-D-glucopyranos ide. Grade: >98%. CAS No. 64032-49-1. Molecular formula: C20H24O9. Mole weight: 408.40. | |
| Toralizumab | Toralizumab (IDEC-131) is a humanized monoclonal antibody (mAb) against CD40L (CD154) comprised of human gamma 1 heavy chains and human kappa light chains. Toralizumab binds specifically to human CD40L on T cells, thereby preventing CD40 signaling. Toralizumab is an immunosuppressive agent. Toralizumab can lead to increased thrombosis. Toralizumab can be studied in research for diseases such as multiple sclerosis, systemic lupus erythematosus (SLE), and Crohns disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IDEC-131; Anti-Human CD40 ligand Recombinant Antibody. CAS No. 252662-47-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99325. | |
| Torasemide | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C16H20N4O3S. CAS No. 56211-40-6. Prepack ID 86431125-1g. Molecular Weight 348.42. See USA prepack pricing. |  |
| Torasemide EP impurity B | Torasemide EP impurity B. Uses: For analytical and research use. CAS No. 72811-73-5. Molecular formula: C12H13N3O2S. Mole weight: 263.32. Catalog: APB72811735. | |
| Torasemi impurity 10 | Torasemi impurity 10. Uses: For analytical and research use. CAS No. 51498-37-4. Molecular formula: C5H5NO4S. Mole weight: 175.16. Catalog: APB51498374. | |
| Torasemi impurity 11 | Torasemi impurity 11. Uses: For analytical and research use. CAS No. 106944-62-1. Molecular formula: C16H20N4O3S. Mole weight: 348.42. Catalog: APB106944621. | |
| Torasemi impurity 12 | Torasemi impurity 12. Uses: For analytical and research use. CAS No. 106944-63-2. Molecular formula: C16H20N4O3S. Mole weight: 348.42. Catalog: APB106944632. | |
| Torasemi impurity 8 | Torasemi impurity 8. Uses: For analytical and research use. Molecular formula: C6H8N2O3S. Mole weight: 188.2. Catalog: APB09913. | |
| Torasemi impurity 9 | Torasemi impurity 9. Uses: For analytical and research use. Molecular formula: C6H7NO4S. Mole weight: 189.19. Catalog: APB09912. | |
| Torcetrapib | Cholesteryl ester transfer protein (CETP) inhibitor. Antilipemic; antiatherosclerotic. Group: Biochemicals. Alternative Names: (2R, 4S) -4-[[[3, 5-Bis (trifluoromethyl) phenyl]methyl] (methoxycarbonyl) amino]-2-ethyl-3, 4-dihydro-6- (trifluoromethyl) -. Grades: Highly Purified. CAS No. 262352-17-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Torcetrapib | Torcetrapib (CP-529414) is a selective, potent cholesteryl ester transfer protein (CETP) inhibitor. A typical inhibition curve for whole human plasma, having a CETP concentration of 37 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP-529414. CAS No. 262352-17-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12089. | |
| Toreforant | Toreforant is a potent and selective histamine H4 receptor (H4R) antagonist, with a Ki at the human receptor of 8.4 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JNJ-38518168. CAS No. 952494-46-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16756. | |
| Toremifene | Toremifene (Z-Toremifene) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.07 μM and 2.6 μM, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Z-Toremifene; NK 622 free base; FC-1157a free base. CAS No. 89778-26-7. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg. Product ID: HY-B0005A. | |
| Toremifene citrate | Toremifene citrate. Group: Biochemicals. Alternative Names: 2-[4-[(1Z)-4-Chloro-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine 2-hydroxy-1,2,3-propanetricarboxylate. Grades: Highly Purified. CAS No. 89778-27-8. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C32H36ClNO8. US Biological Life Sciences. | Worldwide |
| Toremifene citrate | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C32H36ClNO8. CAS No. 89778-27-8. Prepack ID 10914059-100mg. Molecular Weight 598.08. See USA prepack pricing. | |
| Toremifene citrate | Toremifene citrate (Z-Toremifene citrate) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.07 μM and 2.6 μM, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Z-Toremifene citrate; NK 622; FC-1157a. CAS No. 89778-27-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0005. | |
| Toremifene N-Oxide | Toremifene N-Oxide. Group: Biochemicals. Alternative Names: 2-[4-[(1Z)-4-Chloro-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine N-Oxide. Grades: Highly Purified. CAS No. 163130-29-8. Pack Sizes: 10mg. Molecular Formula: C26H28ClNO2, Molecular Weight: US Biological Life Sciences. | Worldwide |
| Toremifene N-Oxide-d6 | Toremifene N-Oxide-d6. Group: Biochemicals. Alternative Names: 2-[4-[(1Z)-4-Chloro-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine N-Oxide-d6. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C26H22D6ClNO2, Molecular Weight: 428. US Biological Life Sciences. | Worldwide |
| Torin 1 | Torin 1 is a potent and selective mTOR inhibitor (IC50 = 2-10nM for mTORC1 and mTORC2). Displays 200-fold selectivity for mTOR over DNA-PK, ATM and hVps34. Group: Biochemicals. Grades: Highly Purified. CAS No. 1222998-36-8. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C??H??F?N?O?. US Biological Life Sciences. | Worldwide |
| Torin 1 | Torin 1 is a potent inhibitor of mTORC1/2 with IC50 of 2 nM/10 nM in cell-free assays; exhibits 1000-fold selectivity for mTOR than PI3K. Group: Inhibitors. CAS No. 1222998-36-8. Pack Sizes: 10mg. Product ID: S2827. Formula: C35H28F3N5O2. Smiles: CCC(=O)N1CCN(CC1)C2=C(C=C(C=C2)N3C(=O)C=CC4=CN=C5C=CC(=CC5=C43)C6=CC7=CC=CC=C7N=C6)C(F)(F)F. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Torin 1 | Torin 1 is a potent inhibitor of mTOR with an IC50 of 3 nM. Torin 1 inhibits both mTORC1/2 complexes with IC50 values between 2 and 10 nM. Torin 1 is an effective inducer of autophagy. Uses: Scientific research. Category: Signaling pathways. CAS No. 1222998-36-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13003. | |
| Torin 1 | Torin 1 Inhibitor. Uses: Scientific use. Product Category: T6045. CAS No. 1222998-36-8. |  |
| Torin 2 | Torin 2 is an mTOR inhibitor with EC50 of 0.25 nM for inhibiting cellular mTOR activity, and exhibits 800-fold selectivity over PI3K (EC50: 200 nM). Torin 2 also inhibits DNA-PK with an IC50 of 0.5 nM in the cell free assay. Torin 2 can suppress both mTORC1 and mTORC2. Uses: Scientific research. Category: Signaling pathways. CAS No. 1223001-51-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13002. | |
| Torin 2 | Torin 2. Group: Biochemicals. Alternative Names: 9- (6-Amino-3-pyridinyl) -1-[3- (trifluoromethyl) phenyl]-benzo[h]-1, 6-naphthyridin-2 (1H) -one. Grades: Highly Purified. CAS No. 1223001-51-1. Pack Sizes: 5mg. Molecular Formula: C24H15F3N4O, Molecular Weight: 432.4. US Biological Life Sciences. | Worldwide |
| Toripalimab | Toripalimab is a selective, recombinant, humanized monoclonal antibody against PD-1. Toripalimab is able to bind to PD-1 and block the interaction with its ligands. Toripalimab has exhibited primary anti-tumor effects in tumors such as melanoma, lung cancer, digestive tract tumors, hepatobiliary and pancreatic tumors, neuroendocrine neoplasms, nasopharyngeal carcinoma and urothelial carcinoma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JS-001. CAS No. 1924598-82-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P9978. | |
| Torkinib | Torkinib (PP 242) is a selective and ATP-competitive mTOR inhibitor with an IC50 of 8 nM[1]. PP242 inhibits both mTORC1 and mTORC2 with IC50s of 30 nM and 58 nM, respectively[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PP 242. CAS No. 1092351-67-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10474. | |
| Tormentic acid | Tormentic acid is a terpenoid isolated from the herb of Potentilla tormentilla. It inhibits LPS-induced iNOS, COX-2, and TNF-α expression through inactivation of the nuclear factor-κb pathway in RAW 264.7 macrophages. Synonyms: Jacarandic acid; (1R,2R,4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-1,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid; 2α,19α-Dihydroxyursolic acid. Grade: >98%. CAS No. 13850-16-3. Molecular formula: C30H48O5. Mole weight: 488.709. | |
| Tormentic acid | Tormentic acid. Alternative Names: (2α,3β)-2,3,19-trihydroxy-urs-12-en-28-oic acid. CAS No. 13850-16-3. Purity: >95.0%. Product ID: FFC-AR-13850163. Molecular formula: C30H48O5. Mole weight: 488.7. IUPAC Name: (1R,2R,4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-1,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Tormentic acid | Tormentic acid. Group: Biochemicals. Grades: Plant Grade. CAS No. 13850-16-3. Pack Sizes: 5mg. Molecular Formula: C30H48O5, Molecular Weight: 488.7. US Biological Life Sciences. | Worldwide |
| Torreyanic acid | Torreyanic acid is a dimer quinone obtained from the endophytic bacterium Pestalotiopsis microspora. Torreyanic acid is cytotoxic to tumor cells and is 5-10 times more effective in cell lines sensitive to protein kinase C agonists. CAS No. 176260-42-7. Molecular formula: C38H44O12. Mole weight: 692.75. | |
| Torsemide | Torsemide is a high-ceiling loop diuretic with a longer duration of action and greater oral bioavailability compared to furosemide. The drug is a pyridine-sulfonylurea derivative that acts on the thick ascending limb of the loop of Henle. Applications: Torsemide is indicated for the treatment of edema associated with congestive heart failure, hepatic cirrhosis, and renal disease, as well as for hypertension. its superior bioavailability makes it more reliable in patients with edema-related gut wall edema. some studies suggest lower mortality and hospitalization rates when torsemide is used in heart failure compared to furosemide, though it is not yet universally preferred. Category: Active pharmaceutical ingredients. Synonyms: Luprac; Torasemida; Torasemidum; BM-02015; AC-4464; Torasemide anhydrous. CAS No. 56211-40-6. Product ID: API0231591. Molecular formula: C16H20N4O3S. Mole weight: 348.4. EINECS: 637-197-3. InChIKey: NGBFQHCMQULJNZ-UHFFFAOYSA-N. Appearance: White to off-white crystalline powder. |  |
| Torsemide | Torsemide. Group: Biochemicals. Alternative Names: N-[[ (1-Methylethyl) amino]carbonyl]-4-[ (3-methylphenyl) amino]-3-pyridinesulfonamide; AC-4464; BM-02015. Grades: Highly Purified. CAS No. 56211-40-6. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C16H20N4O3S. US Biological Life Sciences. | Worldwide |
| Torsemide | Torsemide (Torasemide) is an orally active loop diuretic. Torsemide has anti-aldosterone and vasodilatory effects. Torsemide also can be used for the research of heart failure, renal disease and hepatic cirrhosis[1][1][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Torasemide. CAS No. 56211-40-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0247. | |
| Torsemide-d7 | Torsemide-d7 is the deuterium labeled Torsemide. Torsemide (Torasemide) is an orally active loop diuretic. Torsemide has anti-aldosterone and vasodilatory effects. Torsemide also can be used for the research of heart failure, renal disease and hepatic cirrhosis[1][1][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Torasemide-d7. CAS No. 1189375-06-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-B0247S. | |
| Torsemide-[d7] | Torsemide-[d7] is the labelled analogue of Torsemide, an anilinopyridine sulfonylurea derivative and has been found to be used as an diuretic agent. Synonyms: Torsemide D7; N-[[(1-Methylethyl-d7)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide. Grade: 95% by HPLC; 98% atom D. CAS No. 1189375-06-1. Molecular formula: C16H13D7N4O3S. Mole weight: 355.46. | |
Our database is helping our users find suppliers everyday.
