A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
15-PGDH-IN-1 is a potent and orally active 15-PGDH inhibitior. 15-PGDH-IN-1 has inhibition activity against recombinant human 15-PGDH with an IC50 value of 3 nM. 15-PGDH-IN-1 can be used for the research of tissue repair and regeneration[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2241676-74-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151807.
Involved in histidine biosynthesis. Group: Enzymes. Synonyms: N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase; phosphoribosyl formiminoaminophosphoribosyl imidazolecarboxamide isomerase; N-(phosphoribosylformimino) aminophosphoribosyl imidazolecarboxamide isomerase; 1- (5-phosphoribosyl) -5-[ (5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide ketol-isomerase; 1- (5-phosphoribosyl) -5-[ (5-phosphoribosyla. Enzyme Commission Number: EC 5.3.1.16. CAS No. 37318-43-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5457; 1- (5-phosphoribosyl) -5-[ (5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide isomerase; EC 5.3.1.16; 37318-43-7; N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase; phosphoribosyl formiminoaminophosphoribosyl imidazolecarboxamide isomerase; N-(phosphoribosylformimino) aminophosphoribosyl imidazolecarboxamide isomerase; 1- (5-phosphoribosyl) -5-[ (5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide ketol-isomerase; 1- (5-phosphoribosyl) -5-[ (5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide aldose-ketose-isomerase. Cat No: EXWM-5457.
15(R)-15-Methyl prostaglandin D2
15(R)-15-Methyl PGD2 is a selective, potent agonist for the CRTH2/DP2 receptor. Synonyms: 15(R)-15-methyl PGD2; 15(R)-15-methyl Prostaglandin D2. Grade: ≥95%. CAS No. 210978-26-0. Molecular formula: C21H34O5. Mole weight: 366.5.
15(R)-17-Phenyl trinor prostaglandin F2α
15(R)-17-Phenyl trinor prostaglandin F2α is an impurity of the antiglaucoma agent Bimatoprost. It is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor. Synonyms: 15-epi Bimatoprost; 15(R)-Bimatoprost; 15(R)-17-phenyl trinor PGF2α; (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid. Grade: ≥98%. CAS No. 41639-71-8. Molecular formula: C23H32O5. Mole weight: 388.5.
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 value for the free acid forms of 15(R)-17-phenyl trinor PGF2α wa determined to be 30 nM in a FP receptor binding assay using the cat iris sphincter muscle. Synonyms: 9α,11α,15R-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid, isopropyl ester; 15-epi Bimatoprost isopropylester; 15(R)-Bimatoprost isopropyl ester; 15(R)-17-phenyl trinor PGF2α isopropyl ester; Isopropyl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl}-5-heptenoate; 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)-. Grade: 98%. CAS No. 130273-87-9. Molecular formula: C26H38O5. Mole weight: 430.59.
15(R)-Carboprost
15(R)-Carboprost is the 15(R)-isomer of Carboprost (C177580) and was shown to have antifertility activity in hamsters. Group: Biochemicals. Grades: Highly Purified. CAS No. 35864-81-4. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C21H36O5, Molecular Weight: 368.51. US Biological Life Sciences.
Many of the effects of prostaglandin D2 (PGD2) are transduced via a traditional 7-transmembrane GPCR, the DP1 receptor. 15(R)-15-methyl PGD2 is a surprisingly potent agonist at the DP2 receptor. Synonyms: 15(R)-PGD2; (5Z,9a,13E,15R)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic acid. Grade: ≥98%. CAS No. 59894-05-2. Molecular formula: C20H32O5. Mole weight: 352.5.
15(R)-Prostaglandin E1
15(R)-PGE1 is the unnatural C-15 stereoisomer of PGE1. Synonyms: 15(R)-PGE1; 15-epi PGE1; 15-Epiprostaglandin E1. Grade: ≥95%. CAS No. 20897-91-0. Molecular formula: C20H34O5. Mole weight: 354.5.
15(R)-Prostaglandin F2α
15(R)-PGF2α is the C-15 epimer of the naturally occurring mammalian autacoid PGF2α. It has only 25% of the potency of PGF2α in hamster antifertility studies, which may be due to reduced affinity for FP receptors. Synonyms: 15-beta PGF2α; Prostaglandin F2α (15 beta epimer); 15-epi-PGF2alpha; 15R-Prostaglandin F2alpha. Grade: >99%. CAS No. 37658-84-7. Molecular formula: C20H34O5. Mole weight: 354.49.
15(R)-trans-Latanoprost (10.0 mg in 1. 0ml methyl acetate)
15(R)-trans-Latanoprost is a prostaglandin analog, exhibiting remarkable efficacy in the research of both glaucoma and ocular hypertension, reducing intraocular pressure and thereby averting the perils of vision deterioration. Grade: > 95%. Molecular formula: C26H40O5. Mole weight: 432.61.
15(S)-15-methyl Prostaglandin D2
15(S)-15-methyl Prostaglandin D2 is a synthetic analog of PGD2. Group: Biochemicals. Grades: Highly Purified. CAS No. 85280-90-6. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C21H34O5, Molecular Weight: 366.49. US Biological Life Sciences.
Worldwide
15(S)-Fluprostenol
15(S)-fluprostenol is less active as an FP agonist than 15(R)-fluprostenol. Synonyms: 16-(3-(Trifluoromethyl)phenoxy)-17,18,19,20-tetranor-2,3-cis-didehydro-pgf1-alpha; (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoic acid. Grade: ≥98%. CAS No. 54276-24-3. Molecular formula: C23H29F3O6. Mole weight: 458.5.
15(S)-HEDE
15(S)-HEDE has been identified in psoriatic skin scale extracts (undetermined 15-OH stereochemistry) and inhibits 5-LO (5-lipoxygenase) with an IC50 of 26 μM. Synonyms: (15S)-15-hydroxyicosa-11,13-dienoic acid. Grade: ≥98%. CAS No. 92693-04-4. Molecular formula: C20H36O3. Mole weight: 324.5.
15(S)-HEPE
15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid by 15-lipoxygenase (15-LO). Serum levels of 15(S)-HEPE are elevated in patients with asthma. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 15(S)-hydroxy-Eicosapentaenoic acid; 15(S)-hydroxy EPA. CAS No. 86282-92-0. Pack Sizes: 25 μg (314.02 μM * 250 μL in Ethanol); 50 μg (314.02 μM * 500 μL in Ethanol). Product ID: HY-130675A.
15(S)-HEPE
15(S)-HEPE is a polyunsaturated fatty acid that is a monohydroxy fatty acid synthesized from EPA by the action of 15-LO. Synonyms: 15S-hydroxy-5Z,8Z,11Z,13E,17Z-eicosapentaenoic acid. Grade: ≥95%. CAS No. 86282-92-0. Molecular formula: C20H30O3. Mole weight: 318.45.
15(S)-HETE
15(S)-HETE is an arachidonic acid metabolite with immunosuppressive activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 54845-95-3. Pack Sizes: 50ug, 100ug. Molecular Formula: C20H32O3, Molecular Weight: 320.47. US Biological Life Sciences.
Worldwide
15(S)-HETE-d8
15(S)-HETE-d8 is an internal standard for the quantification of 15(S)-HETE. Group: Biochemicals. Grades: Highly Purified. CAS No. 84807-87-4. Pack Sizes: 25ug, 50ug. Molecular Formula: C20H24D8O3, Molecular Weight: 328.52. US Biological Life Sciences.
Arachidonoyl ethanolamide (AEA) was the first endogenous cannabinoid (CB) to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as THC. 15(S)-HETE ethanolamide is less potent than AEA at the CB1 receptor (Ki of 600 versus 90 nM). 15(S)-HETE ethanolamide also inhibits fatty acid amide hydrolase. Synonyms: 15(S)-hydroxy-N-(2-hydroxyethyl)-5Z,8Z,11Z,13E-eicosatetraenamide; 15(S)-HAEA. Grade: >98%. CAS No. 161744-53-2. Molecular formula: C22H37NO3. Mole weight: 363.5.
15(S)-HETrE
15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of DGLA. It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 μM. Synonyms: (15S)-15-hydroxyicosa-8,11,13-trienoic acid. Grade: ≥98%. CAS No. 92693-02-2. Molecular formula: C20H34O3. Mole weight: 322.5.
15(S)-HpETE
15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. Synonyms: (S)-15-hpete; 15-Hydroperoxyicosatetraenoate; 15-Hydroperoxyeicosatetraenoate. Grade: ≥98%. CAS No. 70981-96-3. Molecular formula: C20H32O4. Mole weight: 336.5.
15(S)-HPETE
15(S)-HPETE is a primary metabolite of arachidonic acid shown to inhibit arachidonic acid induced platelet aggregation. Group: Biochemicals. Grades: Highly Purified. CAS No. 70981-96-3. Pack Sizes: 50ug, 100ug. Molecular Formula: C20H32O4, Molecular Weight: 336.47. US Biological Life Sciences.
Worldwide
15(S)-HPETE
15(S)-HPETE is a precursor of 15(S)-HETE (HY-113336). 15(S)-HPETE is a product of Arachidonic acid (HY-109590) in the 15-lipoxygenase pathway. 15(S)-HPETE reduces Bcl-2, Akt, and phosphorylated Akt protein levels. 15(S)-HPETE induces Apoptosis. 15(S)-HPETE antagonizes the angiogenic effects of 15(S)-HETE. 15(S)-HPETE exhibits antitumor effects against chronic myeloid leukemia. 15(S)-HPETE can be used in adipose tissue explant studies[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 70981-96-3. Pack Sizes: 25 μg (297.20 μM * 250 μL in Ethanol). Product ID: HY-113438.
15(S)-Latanoprost
An impurity of Latanoprost, a medication used to treat glaucoma and ocular hypertension. Synonyms: (15S)-Latanoprost; Latanoprost USP Related Compound B. Grade: > 95%. CAS No. 145773-22-4. Molecular formula: C26H40O5. Mole weight: 432.61.
1-[(5-Trimethylsilyl)oxy-2-pyrimidinyl]-4-piperidinepropanol is derived from 4- (3-Hydroxypropyl) piperidine (H952655), which is used in the synthesis of G-protein coupled receptor (GPR119) agonists based on a bicyclic amine scaffold. Also used in the synthesis and antimicrobial activities of novel quinoline derivatives. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C15H27N3O2Si, Molecular Weight: 309.48. US Biological Life Sciences.
16:0-18:1 PI(4)P Diammonium salt, a phosphatidylinositol, is a complex molecule embedded within the cell membrane. It has been closely associated with pathologies such as cancer, Alzheimer's, and diabetes, lending it to extensive biomedical research. The salt is particularly notable for its capacity to regulate specific cellular pathways in drug development. Understanding the complex implications of this molecule requires a multidisciplinary approach, involving the integration of biochemistry, pharmacology, and medical sciences. Synonyms: 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-myo-inositol-4'-phosphate) (ammonium salt); D-myo-Inositol, 4-(dihydrogen phosphate) 1-[(2R)-3-[(1-oxohexadecyl)oxy]-2-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propyl hydrogen phosphate], ammonium salt (1:2). Grade: >99%. CAS No. 2260795-75-1. Molecular formula: C43H88N2O16P2. Mole weight: 951.11.
16:0 Azido Coenzyme A Ammonium salt is a biochemical reagent mostly used in research related to lipid metabolism and protein modification studies. This product can also help to investigate possible new treatment approaches for metabolic disorders or diseases. Synonyms: 16-azidohexadecanoyl Coenzyme A (ammonium salt). Grade: >99%. CAS No. 2260670-37-7. Molecular formula: C37H74N13O17P3S. Mole weight: 1098.05.
16:0 Biotinyl PE (sodium salt)
16:0 Biotinyl PE (sodium salt) is a phospholipid conjugated with biotin, employed in lipid metabolism research and exploration of cellular signaling pathways. Its utility extends to drug delivery systems tailored for biotin deficiency or metabolic disorders, warranting attention in the realm of targeted therapies. Synonyms: 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl) (sodium salt); 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl) (sodium salt). Grade: >99%. CAS No. 384835-54-5. Molecular formula: C47H87N3O10PNaS. Mole weight: 940.24.
16:0 cholesteryl-d7 ester. Alternative Names: cholesteryl-d7 palmitate. CAS No. 1416275-32-5. Purity: >99%. Product ID: ALCFA1416275325. Molecular formula: C43H69D7O2. Mole weight: 632.105. Alfa Chemistry - ISO 9001:32057 Certified.
16:0(d4) Coenzyme A
16:0(d4) Coenzyme A. Alternative Names: palmitoyl(11,11,12,12-d4) Coenzyme A. CAS No. 2260670-64-0. Purity: >99%. Product ID: ALCFA2260670640. Molecular formula: C37H71D4N10O17P3S. Mole weight: 1061.07. Alfa Chemistry - ISO 9001:32057 Certified.
16:0 DAP
16:0 DAP is a cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 96326-74-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-144022.
1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of five different G protein-coupled receptors (GPCRs) to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Synonyms: 1-hexadecanoyl-sn-glycero-3-phosphate (sodium salt); PA(16:0/0:0); 1-Palmitoyl lysophosphatidic acid sodium salt. Grade: ≥98%. CAS No. 17618-08-5. Molecular formula: C19H38NaO7P. Mole weight: 454.45.
16:0 Lyso PE
16:0 Lyso PE is a naturally occurring lysophospholipid. 16:0 Lyso PE inhibits the growth of L. donovani promastigotes. It has been used to degranulate human eosinophils. Synonyms: 16:0 LPE; 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine; 1-Palmitoyl-2-hydroxy-sn-glycero-3-Phosphoethanolamine. Grade: ≥98%. CAS No. 53862-35-4. Molecular formula: C21H44NO7P. Mole weight: 453.55.
The molecular weight and exact mass are averages based on the polydispersity of PEG. Synonyms: 1,2-dipalmitoyl-sn-glycero-3-phospho((ethyl-1',2',3'-triazole)triethyleneglycolmannose) (ammonium salt); D-L-Mannopyranoside, 2-[2-[2-[4-[(7R)-4-hydroxy-4-oxido-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacos-1-yl]-1H-1,2,3-triazol-1-yl]ethoxy]ethoxy]ethyl, ammonium salt (1:1). Grade: >99%. CAS No. 2260670-46-8. Molecular formula: C51H99N4O16P (average MW due to polydispersity of PEG). Mole weight: 1055.32.
16:0 PA (sodium salt)
DPPA is a glycerophospholipid used in the characterization of polymer-stabilized liposome system. Synonyms: 1,2-DPPA; 1,2-dipalmitoyl-sn-glycero-3-phosphate (sodium salt); DPPA-Na. Grade: 99%. CAS No. 169051-60-9. Molecular formula: C35H68NaO8P. Mole weight: 670.87.